Yuji Mishina - Publications

Affiliations: 
Biologic & Materials Sciences University of Michigan, Ann Arbor, Ann Arbor, MI 

239 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Yang R, Chu H, Yue H, Mishina Y, Zhang Z, Liu H, Li B. BMP signaling maintains auricular chondrocyte identity and prevents microtia development by inhibiting protein kinase A. Elife. 12. PMID 38690987 DOI: 10.7554/eLife.91883  0.361
2023 Yamaguchi H, Li M, Kitami M, Swaminathan S, Mishina Y, Komatsu Y. Enhanced BMP signaling in Cathepsin K-positive tendon progenitors induces heterotopic ossification. Biochemical and Biophysical Research Communications. 688: 149147. PMID 37948912 DOI: 10.1016/j.bbrc.2023.149147  0.363
2023 Kim JK, Villa-Diaz LG, Saunders TL, Saul RP, Timilsina S, Liu F, Mishina Y, Krebsbach PH. Selective Inhibition of mTORC1 Signaling Supports the Development and Maintenance of Pluripotency. Stem Cells (Dayton, Ohio). PMID 37931173 DOI: 10.1093/stmcls/sxad079  0.319
2023 Ishan M, Wang Z, Zhao P, Yao Y, Stice SL, Wells L, Mishina Y, Liu HX. Taste papilla cell differentiation requires the regulation of secretory protein production by ALK3-BMP signaling in the tongue mesenchyme. Development (Cambridge, England). 150. PMID 37680190 DOI: 10.1242/dev.201838  0.411
2023 Yamaguchi H, Swaminathan S, Mishina Y, Komatsu Y. Enhanced BMP signaling leads to enlarged nasal cartilage formation in mice. Biochemical and Biophysical Research Communications. 678: 173-178. PMID 37640003 DOI: 10.1016/j.bbrc.2023.08.053  0.368
2023 Ueharu H, Mishina Y. BMP signaling during craniofacial development: new insights into pathological mechanisms leading to craniofacial anomalies. Frontiers in Physiology. 14: 1170511. PMID 37275223 DOI: 10.3389/fphys.2023.1170511  0.41
2023 Ishan M, Wang Z, Zhao P, Yao Y, Stice S, Wells L, Mishina Y, Liu HX. Taste papilla cell differentiation requires tongue mesenchyme via ALK3-BMP signaling to regulate the production of secretory proteins. Biorxiv : the Preprint Server For Biology. PMID 37066397 DOI: 10.1101/2023.04.03.535414  0.406
2023 Ueharu H, Pan H, Liu X, Ishii M, Pongetti J, Kulkarni AK, Adegbenro FE, Wurn J, Maxson RE, Sun H, Komatsu Y, Zhang H, Yang J, Mishina Y. Augmentation of BMP Signaling in Cranial Neural Crest Cells Leads to Premature Cranial Sutures Fusion through Endochondral Ossification in Mice. Jbmr Plus. 7: e10716. PMID 37065628 DOI: 10.1002/jbm4.10716  0.391
2023 Omi M, Koneru T, Lyu Y, Haraguchi A, Kamiya N, Mishina Y. Increased BMP-Smad signaling does not affect net bone mass in long bones. Frontiers in Physiology. 14: 1145763. PMID 37064883 DOI: 10.3389/fphys.2023.1145763  0.316
2022 Zhang H, Chinoy A, Mousavi P, Beeler A, Louie K, Collier C, Mishina Y. Elevated WNT signaling and compromised Hedgehog signaling due to loss of function contribute to the abnormal molar patterning. Frontiers in Dental Medicine. 3. PMID 38606060 DOI: 10.3389/fdmed.2022.876015  0.334
2022 Yamaguchi H, Shen J, Little DR, Li M, Sozen S, Suzuki K, Mishina Y, Komatsu Y. Enhanced BMP signaling through ALK2 attenuates keratinocyte differentiation. Biochemical and Biophysical Research Communications. 629: 101-105. PMID 36116371 DOI: 10.1016/j.bbrc.2022.09.014  0.31
2022 Qi S, Wang Y, Wei X, Xie D, Mohsen R, Hsieh YL, Mishina Y, Liu F. Expression of Cre recombinase in chondrocytes causes abnormal craniofacial and skeletal development. Transgenic Research. PMID 35526258 DOI: 10.1007/s11248-022-00308-8  0.31
2021 Snider TN, Louie KW, Zuzo G, Ruellas ACO, Solem RC, Cevidanes LHS, Zhang H, Mishina Y. Quantification of three-dimensional morphology of craniofacial mineralized tissue defects in Tgfbr2/Osx-Cre mice. Oral Science International. 18: 193-202. PMID 34720652 DOI: 10.1002/OSI2.1099  0.387
2021 Hsieh YL, Wei X, Wang Y, Zhang H, Qi S, Xie D, Mishina Y, Mendonça D, Hatch N, Liu F. Chondrocyte Tsc1 controls cranial base bone development by restraining the premature differentiation of synchondroses. Bone. 116142. PMID 34365025 DOI: 10.1016/j.bone.2021.116142  0.382
2021 Tomayko MM, Karaaslan S, Lainez B, Conter LJ, Song E, Venkatesan S, Mishina Y, Shlomchik MJ. Roles of Bone Morphogenetic Protein Receptor 1A in Germinal Centers and Long-Lived Humoral Immunity. Immunohorizons. 5: 284-297. PMID 33975878 DOI: 10.4049/immunohorizons.2100019  0.307
2021 Gokhman D, Agoglia RM, Kinnebrew M, Gordon W, Sun D, Bajpai VK, Naqvi S, Chen C, Chan A, Chen C, Petrov DA, Ahituv N, Zhang H, Mishina Y, Wysocka J, et al. Human-chimpanzee fused cells reveal cis-regulatory divergence underlying skeletal evolution. Nature Genetics. PMID 33731941 DOI: 10.1038/s41588-021-00804-3  0.302
2021 Yang J, Kitami M, Pan H, Nakamura MT, Zhang H, Liu F, Zhu L, Komatsu Y, Mishina Y. Augmented BMP signaling commits cranial neural crest cells to a chondrogenic fate by suppressing autophagic β-catenin degradation. Science Signaling. 14. PMID 33436499 DOI: 10.1126/scisignal.aaz9368  0.409
2020 Hu Y, Hao X, Liu C, Ren C, Wang S, Yan G, Meng Y, Mishina Y, Shi C, Sun H. Acvr1 deletion in osteoblasts impaired mandibular bone mass through compromised osteoblast differentiation and enhanced sRANKL-induced osteoclastogenesis. Journal of Cellular Physiology. PMID 33251612 DOI: 10.1002/jcp.30183  0.324
2020 Strong AL, Spreadborough PJ, Pagani CA, Haskins RM, Dey D, Grimm PD, Kaneko K, Marini S, Huber AK, Hwang C, Westover K, Mishina Y, Bradley MJ, Levi B, Davis TA. Small molecule inhibition of non-canonical (TAK1-mediated) BMP signaling results in reduced chondrogenic ossification and heterotopic ossification in a rat model of blast-associated combat-related lower limb trauma. Bone. 115517. PMID 32622875 DOI: 10.1016/J.Bone.2020.115517  0.413
2020 Kamiya N, Atsawasuwan P, Joiner DM, Waldorff EI, Goldstein S, Yamauchi M, Mishina Y. Controversy of physiological vs. pharmacological effects of BMP signaling: Constitutive activation of BMP type IA receptor-dependent signaling in osteoblast lineage enhances bone formation and resorption, not affecting net bone mass. Bone. 115513. PMID 32603910 DOI: 10.1016/J.Bone.2020.115513  0.425
2020 Yang J, Ueharu H, Mishina Y. Energy metabolism: A newly emerging target of BMP signaling in bone homeostasis. Bone. 115467. PMID 32512164 DOI: 10.1016/J.Bone.2020.115467  0.399
2020 Zhang H, Zhang Y, Terajima M, Romanowicz G, Liu Y, Omi M, Bigelow E, Joiner DM, Waldorff EI, Zhu P, Raghavan M, Lynch M, Kamiya N, Zhang R, Jepsen KJ, ... Mishina Y, et al. Loss of BMP signaling mediated by BMPR1A in osteoblasts leads to differential bone phenotypes in mice depending on anatomical location of the bones. Bone. 115402. PMID 32360900 DOI: 10.1016/J.Bone.2020.115402  0.387
2020 Omi M, Kulkarni AK, Raichur A, Fox M, Uptergrove A, Zhang H, Mishina Y. BMP-Smad Signaling Regulates Postnatal Crown Dentinogenesis in Mouse Molar. Jbmr Plus. 4: e10249. PMID 32149267 DOI: 10.1002/jbm4.10249  0.43
2020 Sorkin M, Huber AK, Hwang C, Carson WF, Menon R, Li J, Vasquez K, Pagani C, Patel N, Li S, Visser ND, Niknafs Y, Loder S, Scola M, Nycz D, ... ... Mishina Y, et al. Regulation of heterotopic ossification by monocytes in a mouse model of aberrant wound healing. Nature Communications. 11: 722. PMID 32024825 DOI: 10.1038/S41467-019-14172-4  0.348
2019 Hwang C, Marini S, Huber AK, Stepien DM, Sorkin M, Loder S, Pagani CA, Li J, Visser ND, Vasquez K, Garada MA, Li S, Xu J, Hsu CY, Yu PB, ... ... Mishina Y, et al. Mesenchymal VEGFA induces aberrant differentiation in heterotopic ossification. Bone Research. 7: 36. PMID 31840004 DOI: 10.1038/S41413-019-0075-6  0.375
2019 Shafiquzzaman M, Biswas S, Li P, Mishina Y, Li B, Liu H. The non-canonical BMP signaling pathway plays an important role in club cell regeneration. Stem Cells (Dayton, Ohio). PMID 31758827 DOI: 10.1002/Stem.3125  0.405
2019 Omi M, Kaartinen V, Mishina Y. Activin A receptor type 1-mediated BMP signaling regulates RANKL-induced osteoclastogenesis via canonical SMAD signaling pathway. The Journal of Biological Chemistry. PMID 31619522 DOI: 10.1074/Jbc.Ra119.009521  0.534
2019 Ishan M, Chen G, Sun C, Chen SY, Komatsu Y, Mishina Y, Liu HX. Increased activity of mesenchymal ALK2-BMP signaling causes posteriorly truncated microglossia and disorganization of lingual tissues. Genesis (New York, N.Y. : 2000). e23337. PMID 31571391 DOI: 10.1002/Dvg.23337  0.523
2019 Valer JA, Sánchez-de-Diego C, Gámez B, Mishina Y, Rosa JL, Ventura F. Inhibition of phosphatidylinositol 3-kinase α (PI3Kα) prevents heterotopic ossification. Embo Molecular Medicine. e10567. PMID 31373426 DOI: 10.15252/Emmm.201910567  0.381
2019 Thomas N, Choi HK, Wei X, Wang L, Mishina Y, Guan JL, Liu F. Autophagy Regulates Craniofacial Bone Acquisition. Calcified Tissue International. PMID 31372669 DOI: 10.1007/S00223-019-00593-2  0.359
2019 Rajderkar S, Mann JM, Panaretos C, Yumoto K, Li HD, Mishina Y, Ralston B, Kaartinen V. Trim33 is required for appropriate development of pre-cardiogenic mesoderm. Developmental Biology. PMID 30940539 DOI: 10.1016/J.Ydbio.2019.03.018  0.386
2019 Sung Hsieh HH, Agarwal S, Cholok DJ, Loder SJ, Kaneko K, Huber A, Chung MT, Ranganathan K, Habbouche J, Li J, Butts J, Reimer J, Kaura A, Drake J, Breuler C, ... ... Mishina Y, et al. Coordinating Tissue Regeneration through TGF-β Activated Kinase 1 (TAK1) In-activation and Re-activation. Stem Cells (Dayton, Ohio). PMID 30786091 DOI: 10.1002/Stem.2991  0.356
2019 Yang J, Mishina Y. Phenotypic Analyses of Genetically Modified Mice for BMP Receptors. Methods in Molecular Biology (Clifton, N.J.). 1891: 179-189. PMID 30414133 DOI: 10.1007/978-1-4939-8904-1_13  0.476
2019 Yang J, Mishina Y. Generation and Identification of Genetically Modified Mice for BMP Receptors. Methods in Molecular Biology (Clifton, N.J.). 1891: 165-177. PMID 30414132 DOI: 10.1007/978-1-4939-8904-1_12  0.386
2018 Zhang X, Shi C, Zhao H, Zhou Y, Hu Y, Yan G, Liu C, Li D, Hao X, Mishina Y, Liu Q, Sun H. Distinctive role of ACVR1 in dentin formation: requirement for dentin thickness in molars and prevention of osteodentin formation in incisors of mice. Journal of Molecular Histology. PMID 30519900 DOI: 10.1007/S10735-018-9806-Z  0.524
2018 Kulkarni AK, Louie KW, Yatabe M, Ruellas ACO, Mochida Y, Cevidanes LHS, Mishina Y, Zhang H. A Ciliary Protein EVC2/LIMBIN Plays a Critical Role in the Skull Base for Mid-Facial Development. Frontiers in Physiology. 9: 1484. PMID 30410447 DOI: 10.3389/Fphys.2018.01484  0.366
2018 Gupte MJ, Swanson WB, Hu J, Jin X, Ma H, Zhang Z, Liu Z, Feng K, Feng G, Xiao G, Hatch N, Mishina Y, Ma PX. Pore Size Directs Bone Marrow Stromal Cell Fate and Tissue Regeneration in Nanofibrous Macroporous Scaffolds by Mediating Vascularization. Acta Biomaterialia. PMID 30321630 DOI: 10.1016/J.Actbio.2018.10.016  0.342
2018 Kramer K, Yang J, Swanson WB, Hayano S, Toda M, Pan H, Kim JK, Krebsbach PH, Mishina Y. Rapamycin rescues BMP mediated midline craniosynostosis phenotype through reduction of mTOR signaling in a mouse model. Genesis (New York, N.Y. : 2000). 56: e23220. PMID 30134066 DOI: 10.1002/Dvg.23220  0.492
2018 Zhang X, Liu Q, Zhao H, Hu Y, Liu C, Yan G, Li D, Mishina Y, Shi C, Sun H. ACVR1 is essential for periodontium development and promotes alveolar bone formation. Archives of Oral Biology. 95: 108-117. PMID 30098439 DOI: 10.1016/J.Archoralbio.2018.07.019  0.472
2018 Almehmadi A, Ohyama Y, Kaku M, Alamoudi A, Husein D, Katafuchi M, Mishina Y, Mochida Y. VWC2 Increases Bone Formation Through Inhibiting Activin Signaling. Calcified Tissue International. 103: 663-674. PMID 30074079 DOI: 10.1007/S00223-018-0462-9  0.443
2018 Biswas S, Li P, Wu H, Shafiquzzaman M, Murakami S, Schneider MD, Mishina Y, Li B, Li J. BMPRIA is required for osteogenic differentiation and RANKL expression in adult bone marrow mesenchymal stromal cells. Scientific Reports. 8: 8475. PMID 29855498 DOI: 10.1038/S41598-018-26820-8  0.438
2018 Wang X, Li F, Xie L, Crane J, Zhen G, Mishina Y, Deng R, Gao B, Chen H, Liu S, Yang P, Gao M, Tu M, Wang Y, Wan M, et al. Inhibition of overactive TGF-β attenuates progression of heterotopic ossification in mice. Nature Communications. 9: 551. PMID 29416028 DOI: 10.1038/S41467-018-02988-5  0.393
2018 Liu X, Hayano S, Pan H, Inagaki M, Ninomiya-Tsuji J, Sun H, Mishina Y. Compound mutations in Bmpr1a and Tak1 synergize facial deformities via increased cell death. Genesis (New York, N.Y. : 2000). PMID 29411501 DOI: 10.1002/Dvg.23093  0.408
2018 Patel N, Sorkin M, Hwang C, Li J, Ucer S, Kader S, Vasquez K, Li S, Kumar R, Mishina Y, Levi B. Abstract 86: Systemic Inhibition of Tgfβ Signaling Attenuates Trauma-induced Heterotopic Ossification Plastic and Reconstructive Surgery. Global Open. 6: 68-69. DOI: 10.1097/01.Gox.0000533951.61978.12  0.325
2018 Shi C, Mishina Y. The TGF‐β Superfamily in Bone Formation and Maintenance Primer On the Metabolic Bone Diseases and Disorders of Mineral Metabolism. 60-67. DOI: 10.1002/9781119266594.Ch8  0.335
2017 Shi C, Mandair GS, Zhang H, Vanrenterghem GG, Ridella R, Takahashi A, Zhang Y, Kohn DH, Morris MD, Mishina Y, Sun H. Bone morphogenetic protein signaling through ACVR1 and BMPR1A negatively regulates bone mass along with alterations in bone composition. Journal of Structural Biology. PMID 29175363 DOI: 10.1016/J.Jsb.2017.11.010  0.414
2017 Townsend KL, Madden C, Blaszkiewicz M, McDougall L, Tupone D, Lynes MD, Mishina Y, Yu P, Morrison S, Tseng YH. Re-Establishment of Energy Balance in a Male Mouse Model with POMC Neuron Deletion of BMPR1A. Endocrinology. PMID 29040444 DOI: 10.1210/En.2017-00212  0.396
2017 Cholok D, Chung MT, Ranganathan K, Ucer S, Day D, Davis TA, Mishina Y, Levi B. Heterotopic ossification and the elucidation of pathologic differentiation. Bone. PMID 28987285 DOI: 10.1016/J.Bone.2017.09.019  0.404
2017 Kwon EK, Louie K, Kulkarni A, Yatabe M, Ruellas ACO, Snider TN, Mochida Y, Cevidanes LHS, Mishina Y, Zhang H. The role of Ellis-van Creveld 2(EVC2) in mice during cranial bone development. Anatomical Record (Hoboken, N.J. : 2007). PMID 28950429 DOI: 10.1002/Ar.23692  0.398
2017 Saxon JG, Baer DR, Barton JA, Hawkins T, Wu B, Trusk TC, Harris SE, Zhou B, Mishina Y, Sugi Y. BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling. Developmental Biology. PMID 28790014 DOI: 10.1016/J.Ydbio.2017.08.008  0.418
2017 He Y, Sun X, Wang L, Mishina Y, Guan JL, Liu F. Male Germline Recombination of a Conditional Allele by the Widely Used Dermo1-Cre (Twist2-Cre) Transgene. Genesis (New York, N.Y. : 2000). PMID 28722198 DOI: 10.1002/Dvg.23048  0.375
2017 Agarwal S, Loder SJ, Breuler C, Li J, Cholok D, Brownley C, Peterson J, Hsieh HH, Drake J, Ranganathan K, Niknafs YS, Xiao W, Li S, Kumar R, Tompkins R, ... ... Mishina Y, et al. Strategic Targeting of Multiple BMP Receptors Prevents Trauma-Induced Heterotopic Ossification. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 28716575 DOI: 10.1016/J.Ymthe.2017.01.008  0.398
2017 Pan H, Zhang H, Abraham P, Komatsu Y, Lyons K, Kaartinen V, Mishina Y. BmpR1A is a major type 1 BMP receptor for BMP-Smad signaling during skull development. Developmental Biology. PMID 28641928 DOI: 10.1016/J.Ydbio.2017.06.020  0.519
2017 Sorkin M, Agarwal S, Ranganathan K, Loder S, Cholok D, Fireman D, Li J, Li S, Zhao B, Mishina Y, Cederna P, Levi B. Hair Follicle Specific ACVR1/ALK2 Critically Affects Skin Morphogenesis and Attenuates Wound Healing. Wound Repair and Regeneration : Official Publication of the Wound Healing Society [and] the European Tissue Repair Society. PMID 28513105 DOI: 10.1111/Wrr.12549  0.394
2017 Grafe I, Alexander S, Peterson JR, Snider TN, Levi B, Lee B, Mishina Y. TGF-β Family Signaling in Mesenchymal Differentiation. Cold Spring Harbor Perspectives in Biology. PMID 28507020 DOI: 10.1101/Cshperspect.A022202  0.409
2017 Kaucka M, Zikmund T, Tesarova M, Gyllborg D, Hellander A, Jaros J, Kaiser J, Petersen J, Szarowska B, Newton PT, Dyachuk V, Li L, Qian H, Johansson AS, Mishina Y, et al. Oriented clonal cell dynamics enables accurate growth and shaping of vertebrate cartilage. Elife. 6. PMID 28414273 DOI: 10.7554/Elife.25902  0.324
2017 Li A, Cong Q, Xia X, Leong WF, Yeh J, Miao D, Mishina Y, Liu H, Li B. Pharmacologic Calcitriol Inhibits Osteoclast Lineage Commitment via the BMP-Smad1- IκB-NF-κB Pathway. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 28370465 DOI: 10.1002/Jbmr.3146  0.388
2017 Agarwal S, Loder S, Cholok D, Breuler C, Chung M, Brownley C, Peterson J, Li J, Hsung HH, Ranganathan K, Priest C, Li S, Mishina Y, Levi B. Abstract 128: A Translational Strategy Targeting Type I BMP Receptors to Prevent Heterotopic Ossification. Plastic and Reconstructive Surgery. Global Open. 5: 94. DOI: 10.1097/01.Gox.0000516647.61459.C7  0.329
2017 Loder S, Agarwal S, Hsieh H, Cholok D, Chung M, Li J, Breuler C, Priest C, Ranganathan K, Habbouche J, Kaura A, Butts J, Li S, Mishina Y, Levi B. Abstract 123: Loss Of TGF-beta Activated Kinase (TAK1) Activity Induces Cellular Proliferation And Diminishes Differentiation During Bone Healing Plastic and Reconstructive Surgery. Global Open. 5: 90-91. DOI: 10.1097/01.Gox.0000516642.23341.82  0.36
2017 Cholok D, Chung M, Agarwal S, Loder S, Breuler C, Priest C, Habbouche J, Kaura A, Butts J, Reimer J, Li J, Hsung HH, Ranganathan K, Fireman D, Li S, ... Mishina Y, et al. Abstract 16: Inhibition of mTOR Signaling Reduces Mesenchymal Cell Migration To Sites Of Injury And Eliminates Heterotopic Ossification In A Mouse Model. Plastic and Reconstructive Surgery. Global Open. 5: 12-13. DOI: 10.1097/01.Gox.0000516537.35007.68  0.35
2017 Agarwal S, Chung MT, Loder S, Cholok D, Hsieh HH, Habbouche J, Breuler C, Butts J, Kaura A, Li J, Ranganathan K, Ucer S, Priest C, Li S, Reimer J, ... Mishina Y, et al. Abstract 46. Modulating TAK1 Signaling to Enhance Scaffold and Cell-Free Calvarial Healing. Plastic and Reconstructive Surgery. Global Open. 5: 45. DOI: 10.1097/01.Gox.0000513461.84739.4E  0.369
2016 Zhang H, Takeda H, Tsuji T, Kamiya N, Kunieda T, Mochida Y, Mishina Y. Loss of Function of Evc2 in Dental Mesenchyme Leads to Hypomorphic Enamel. Journal of Dental Research. 22034516683674. PMID 28081373 DOI: 10.1177/0022034516683674  0.4
2016 Zhang H, Kamiya N, Tsuji T, Takeda H, Scott G, Rajderkar S, Ray MK, Mochida Y, Allen B, Lefebvre V, Hung IH, Ornitz DM, Kunieda T, Mishina Y. Elevated Fibroblast Growth Factor Signaling Is Critical for the Pathogenesis of the Dwarfism in Evc2/Limbin Mutant Mice. Plos Genetics. 12: e1006510. PMID 28027321 DOI: 10.1371/Journal.Pgen.1006510  0.472
2016 Agarwal S, Cholok D, Loder S, Li J, Breuler C, Chung MT, Sung HH, Ranganathan K, Habbouche J, Drake J, Peterson J, Priest C, Li S, Mishina Y, Levi B. mTOR inhibition and BMP signaling act synergistically to reduce muscle fibrosis and improve myofiber regeneration. Jci Insight. 1: e89805. PMID 27942591 DOI: 10.1172/Jci.Insight.89805  0.384
2016 Agarwal S, Loder SJ, Cholok D, Peterson J, Li J, Breuler C, Cameron Brownley R, Hsin Sung H, Chung M, Kamiya N, Li S, Zhao B, Kaartinen V, Davis TA, Qureshi AT, ... ... Mishina Y, et al. Scleraxis-Lineage Cells Contribute to Ectopic Bone Formation in Muscle and Tendon. Stem Cells (Dayton, Ohio). PMID 27862618 DOI: 10.1002/Stem.2515  0.414
2016 Shi C, Zhang H, Louie K, Mishina Y, Sun H. BMP Signaling Mediated by BMPR1A in Osteoclasts Negatively Regulates Osteoblast Mineralization through Suppression of Cx43. Journal of Cellular Biochemistry. PMID 27649478 DOI: 10.1002/Jcb.25746  0.468
2016 Agarwal S, Drake J, Qureshi AT, Loder S, Li S, Shigemori K, Peterson J, Cholok D, Forsberg JA, Mishina Y, Davis TA, Levi B. Characterization of Cells Isolated from Genetic and Trauma-Induced Heterotopic Ossification. Plos One. 11: e0156253. PMID 27494521 DOI: 10.1371/Journal.Pone.0156253  0.388
2016 Wei X, Hu M, Mishina Y, Liu F. Developmental Regulation of the Growth Plate and Cranial Synchondrosis. Journal of Dental Research. PMID 27250655 DOI: 10.1177/0022034516651823  0.415
2016 Schulz TJ, Graja A, Huang TL, Xue R, An D, Poehle-Kronawitter S, Lynes MD, Tolkachov A, O'Sullivan LE, Hirshman MF, Schupp M, Goodyear LJ, Mishina Y, Tseng YH. Loss of BMP receptor type 1A in murine adipose tissue attenuates age-related onset of insulin resistance. Diabetologia. PMID 27209464 DOI: 10.1007/S00125-016-3990-8  0.353
2016 Luo Y, Chen H, Ren S, Li N, Mishina Y, Shi W. BMP signaling is essential in neonatal surfactant production during respiratory adaptation. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00391.2015. PMID 27190064 DOI: 10.1152/Ajplung.00391.2015  0.388
2016 Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Alamoudi A, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y. Expression of Evc2 in craniofacial tissues and craniofacial bone defects in Evc2 knockout mouse. Archives of Oral Biology. 68: 142-152. PMID 27164562 DOI: 10.1016/J.Archoralbio.2016.05.002  0.382
2016 Zhang Y, McNerny EG, Terajima M, Raghavan M, Romanowicz G, Zhang Z, Zhang H, Kamiya N, Tantillo M, Zhu P, Scott GJ, Ray MK, Lynch M, Ma PX, Morris MD, ... ... Mishina Y, et al. Loss of BMP signaling through BMPR1A in osteoblasts leads to greater collagen cross-link maturation and material-level mechanical properties in mouse femoral trabecular compartments. Bone. PMID 27113526 DOI: 10.1016/J.Bone.2016.04.022  0.393
2016 Badri MK, Zhang H, Ohyama Y, Venkitapathi S, Kamiya N, Takeda H, Ray M, Scott G, Tsuji T, Kunieda T, Mishina Y, Mochida Y. Ellis van Creveld2 is required for postnatal craniofacial bone development. Anatomical Record (Hoboken, N.J. : 2007). PMID 27090777 DOI: 10.1002/Ar.23353  0.378
2016 Agarwal S, Loder SJ, Sorkin M, Li S, Shrestha S, Zhao B, Mishina Y, James A, Levi B. Analysis of bone-cartilage-stromal progenitor populations in trauma induced and genetic models of heterotopic ossification. Stem Cells (Dayton, Ohio). PMID 27068890 DOI: 10.1002/Stem.2376  0.41
2016 Shi C, Iura A, Terajima M, Liu F, Lyons K, Pan H, Zhang H, Yamauchi M, Mishina Y, Sun H. Deletion of BMP receptor type IB decreased bone mass in association with compromised osteoblastic differentiation of bone marrow mesenchymal progenitors. Scientific Reports. 6: 24256. PMID 27048979 DOI: 10.1038/Srep24256  0.46
2016 Zhou X, Wang Y, Ongaro L, Boehm U, Kaartinen V, Mishina Y, Bernard DJ. Normal gonadotropin production and fertility in gonadotrope-specific BMPR1A knockout mice. The Journal of Endocrinology. PMID 27029473 DOI: 10.1530/Joe-16-0053  0.469
2016 Graf D, Malik Z, Hayano S, Mishina Y. Common mechanisms in development and disease: BMP signaling in craniofacial development. Cytokine & Growth Factor Reviews. 27: 129-39. PMID 26747371 DOI: 10.1016/J.Cytogfr.2015.11.004  0.483
2016 Boggs K, Venkatesan N, Mederacke I, Komatsu Y, Stice S, Schwabe RF, Mistretta CM, Mishina Y, Liu HX. Contribution of Underlying Connective Tissue Cells to Taste Buds in Mouse Tongue and Soft Palate. Plos One. 11: e0146475. PMID 26741369 DOI: 10.1371/Journal.Pone.0146475  0.351
2015 Shrivats AR, McDermott MC, Klimak M, Averick SE, Pan H, Matyjaszewski K, Mishina Y, Hollinger JO. Nanogel-Mediated RNAi Against Runx2 and Osx Inhibits Osteogenic Differentiation in Constitutively Active BMPR1A Osteoblasts. Acs Biomaterials Science & Engineering. 1: 1139-1150. PMID 26985455 DOI: 10.1021/Acsbiomaterials.5B00294  0.429
2015 Agarwal S, Loder S, Brownley C, Cholok D, Mangiavini L, Li J, Breuler C, Sung HH, Li S, Ranganathan K, Peterson J, Tompkins R, Herndon D, Xiao W, Jumlongras D, ... ... Mishina Y, et al. Inhibition of Hif1α prevents both trauma-induced and genetic heterotopic ossification. Proceedings of the National Academy of Sciences of the United States of America. PMID 26721400 DOI: 10.1073/Pnas.1515397113  0.48
2015 Brownley RC, Agarwal S, Loder S, Eboda O, Li J, Peterson J, Hwang C, Breuler C, Kaartinen V, Zhou B, Mishina Y, Levi B. Characterization of Heterotopic Ossification Using Radiographic Imaging: Evidence for a Paradigm Shift. Plos One. 10: e0141432. PMID 26544555 DOI: 10.1371/Journal.Pone.0141432  0.344
2015 Iura A, McNerny EG, Zhang Y, Kamiya N, Tantillo M, Lynch M, Kohn DH, Mishina Y. Mechanical Loading Synergistically Increases Trabecular Bone Volume and Improves Mechanical Properties in the Mouse when BMP Signaling Is Specifically Ablated in Osteoblasts. Plos One. 10: e0141345. PMID 26489086 DOI: 10.1371/Journal.Pone.0141345  0.385
2015 Peterson JR, Agarwal S, Brownley RC, Loder SJ, Ranganathan K, Cederna PS, Mishina Y, Wang SC, Levi B. Direct Mouse Trauma/Burn Model of Heterotopic Ossification. Journal of Visualized Experiments : Jove. PMID 26274052 DOI: 10.3791/52880  0.374
2015 Zhang H, Takeda H, Tsuji T, Kamiya N, Rajderkar S, Louie K, Collier C, Scott G, Ray M, Mochida Y, Kaartinen V, Kunieda T, Mishina Y. Generation of Evc2/Limbin global and conditional KO mice and its roles during mineralized tissue formation. Genesis (New York, N.Y. : 2000). PMID 26219237 DOI: 10.1002/Dvg.22879  0.434
2015 Jiang FX, Mishina Y, Baten A, Morahan G, Harrison LC. Transcriptome of pancreas-specific Bmpr1a-deleted islets links to TPH1-5-HT axis. Biology Open. 4: 1016-23. PMID 26187948 DOI: 10.1242/Bio.011858  0.37
2015 Noda K, Mishina Y, Komatsu Y. Constitutively active mutation of ACVR1 in oral epithelium causes submucous cleft palate in mice. Developmental Biology. PMID 26116174 DOI: 10.1016/J.Ydbio.2015.06.014  0.459
2015 Prideaux M, Dallas SL, Zhao N, Johnsrud ED, Veno PA, Guo D, Mishina Y, Harris SE, Bonewald LF. Parathyroid Hormone Induces Bone Cell Motility and Loss of Mature Osteocyte Phenotype through L-Calcium Channel Dependent and Independent Mechanisms. Plos One. 10: e0125731. PMID 25942444 DOI: 10.1371/Journal.Pone.0125731  0.412
2015 Hayano S, Komatsu Y, Pan H, Mishina Y. Augmented BMP signaling in the neural crest inhibits nasal cartilage morphogenesis by inducing p53-mediated apoptosis. Development (Cambridge, England). 142: 1357-67. PMID 25742798 DOI: 10.1242/Dev.118802  0.444
2015 Agarwal S, Loder SJ, Brownley C, Eboda O, Peterson JR, Hayano S, Wu B, Zhao B, Kaartinen V, Wong VC, Mishina Y, Levi B. BMP signaling mediated by constitutively active Activin type 1 receptor (ACVR1) results in ectopic bone formation localized to distal extremity joints. Developmental Biology. 400: 202-9. PMID 25722188 DOI: 10.1016/J.Ydbio.2015.02.011  0.485
2015 Lim J, Tu X, Choi K, Akiyama H, Mishina Y, Long F. BMP-Smad4 signaling is required for precartilaginous mesenchymal condensation independent of Sox9 in the mouse. Developmental Biology. 400: 132-8. PMID 25641697 DOI: 10.1016/J.Ydbio.2015.01.022  0.537
2015 Wang L, Mishina Y, Liu F. Osterix-Cre transgene causes craniofacial bone development defect. Calcified Tissue International. 96: 129-37. PMID 25550101 DOI: 10.1007/S00223-014-9945-5  0.412
2015 Lane J, Yumoto K, Azhar M, Ninomiya-Tsuji J, Inagaki M, Hu Y, Deng CX, Kim J, Mishina Y, Kaartinen V. Tak1, Smad4 and Trim33 redundantly mediate TGF-β3 signaling during palate development. Developmental Biology. 398: 231-41. PMID 25523394 DOI: 10.1016/J.Ydbio.2014.12.006  0.44
2015 Kajimoto H, Kai H, Aoki H, Uchiwa H, Aoki Y, Yasuoka S, Anegawa T, Mishina Y, Suzuki A, Fukumoto Y, Imaizumi T. BMP type I receptor inhibition attenuates endothelial dysfunction in mice with chronic kidney disease. Kidney International. 87: 128-36. PMID 24963916 DOI: 10.1038/Ki.2014.223  0.374
2015 Agarwal S, Loder SJ, Brownley C, Oluwatobi E, Peterson J, Mishina Y, Buchman SR, Levi B. Abstract P6: Using a Novel Transgenic Mouse to Identify Endochondral Ossification Precursor Cells and to Induce Bone Growth Plastic and Reconstructive Surgery. 135: 1212. DOI: 10.1097/01.Prs.0000463326.38300.13  0.389
2014 Levi B, Agarwal S, Peterson J, Oluwatobi E, Ranganathan K, Mishina Y, Wang SC, Buchman SR, Cederna PS. Abstract 148: use of bmp type I alk-3 knockout mice to develop novel treatment strategies for trauma-induced heterotopic ossification. Plastic and Reconstructive Surgery. 133: 162-3. PMID 25942258 DOI: 10.1097/01.Prs.0000444976.35528.B5  0.343
2014 Brownley C, Agarwal S, Peterson J, Oluwatobi E, Ranganathan K, Wang SC, Mishina Y, Buchman SR, Levi B. Abstract 89: Novel Targeting of the Alk-2 Receptor Using the Cre/lox System to Enhance Osseous Regeneration by Mesenchymal Stem Cells. Plastic and Reconstructive Surgery. 133: 103. PMID 25942200 DOI: 10.1097/01.Prs.0000445122.92738.19  0.348
2014 Li A, Xia X, Yeh J, Kua H, Liu H, Mishina Y, Hao A, Li B. PDGF-AA promotes osteogenic differentiation and migration of mesenchymal stem cell by down-regulating PDGFRα and derepressing BMP-Smad1/5/8 signaling. Plos One. 9: e113785. PMID 25470749 DOI: 10.1371/Journal.Pone.0113785  0.467
2014 Peterson JR, Eboda O, Agarwal S, Ranganathan K, Buchman SR, Lee M, Wang SC, Mishina Y, Levi B. Targeting of ALK2, a Receptor for Bone Morphogenetic Proteins, Using the Cre/lox System to Enhance Osseous Regeneration by Adipose-Derived Stem Cells. Stem Cells Translational Medicine. 3: 1375-80. PMID 25232183 DOI: 10.5966/Sctm.2014-0082  0.468
2014 Jing J, Hinton RJ, Mishina Y, Liu Y, Zhou X, Feng JQ. Critical role of Bmpr1a in mandibular condyle growth. Connective Tissue Research. 55: 73-8. PMID 25158185 DOI: 10.3109/03008207.2014.923858  0.44
2014 Thomas PS, Rajderkar S, Lane J, Mishina Y, Kaartinen V. AcvR1-mediated BMP signaling in second heart field is required for arterial pole development: implications for myocardial differentiation and regional identity. Developmental Biology. 390: 191-207. PMID 24680892 DOI: 10.1016/J.Ydbio.2014.03.008  0.408
2014 Qi H, Jin M, Duan Y, Du X, Zhang Y, Ren F, Wang Y, Tian Q, Wang X, Wang Q, Zhu Y, Xie Y, Liu C, Cao X, Mishina Y, et al. FGFR3 induces degradation of BMP type I receptor to regulate skeletal development. Biochimica Et Biophysica Acta. 1843: 1237-47. PMID 24657641 DOI: 10.1016/J.Bbamcr.2014.03.011  0.514
2014 Mishina Y, Snider TN. Neural crest cell signaling pathways critical to cranial bone development and pathology. Experimental Cell Research. 325: 138-47. PMID 24509233 DOI: 10.1016/J.Yexcr.2014.01.019  0.412
2014 Hager-Theodorides AL, Ross SE, Sahni H, Mishina Y, Furmanski AL, Crompton T. Direct BMP2/4 signaling through BMP receptor IA regulates fetal thymocyte progenitor homeostasis and differentiation to CD4+CD8+ double-positive cell. Cell Cycle (Georgetown, Tex.). 13: 324-33. PMID 24240189 DOI: 10.4161/Cc.27118  0.426
2013 Jing J, Ren Y, Zong Z, Liu C, Kamiya N, Mishina Y, Liu Y, Zhou X, Feng JQ. BMP receptor 1A determines the cell fate of the postnatal growth plate. International Journal of Biological Sciences. 9: 895-906. PMID 24163588 DOI: 10.7150/Ijbs.7508  0.456
2013 Majdazari A, Stubbusch J, Müller CM, Hennchen M, Weber M, Deng CX, Mishina Y, Schütz G, Deller T, Rohrer H. Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 15132-44. PMID 24048844 DOI: 10.1523/Jneurosci.4748-12.2013  0.326
2013 Howden R, Cooley I, Van Dodewaard C, Arthur S, Cividanes S, Leamy L, McCann Hartzell K, Gladwell W, Martin J, Scott G, Ray M, Mishina Y. Cardiac responses to 24 hrs hyperoxia in Bmp2 and Bmp4 heterozygous mice. Inhalation Toxicology. 25: 509-16. PMID 23876042 DOI: 10.3109/08958378.2013.808287  0.316
2013 Yang W, Guo D, Harris MA, Cui Y, Gluhak-Heinrich J, Wu J, Chen XD, Skinner C, Nyman JS, Edwards JR, Mundy GR, Lichtler A, Kream BE, Rowe DW, Kalajzic I, ... ... Mishina Y, et al. Bmp2 in osteoblasts of periosteum and trabecular bone links bone formation to vascularization and mesenchymal stem cells. Journal of Cell Science. 126: 4085-98. PMID 23843612 DOI: 10.1242/Jcs.118596  0.414
2013 Singh AP, Cummings CA, Mishina Y, Archer TK. SOX8 regulates permeability of the blood-testes barrier that affects adult male fertility in the mouse. Biology of Reproduction. 88: 133. PMID 23595903 DOI: 10.1095/Biolreprod.112.107284  0.334
2013 Bagarova J, Vonner AJ, Armstrong KA, Börgermann J, Lai CS, Deng DY, Beppu H, Alfano I, Filippakopoulos P, Morrell NW, Bullock AN, Knaus P, Mishina Y, Yu PB. Constitutively active ALK2 receptor mutants require type II receptor cooperation. Molecular and Cellular Biology. 33: 2413-24. PMID 23572558 DOI: 10.1128/Mcb.01595-12  0.455
2013 Yumoto K, Thomas PS, Lane J, Matsuzaki K, Inagaki M, Ninomiya-Tsuji J, Scott GJ, Ray MK, Ishii M, Maxson R, Mishina Y, Kaartinen V. TGF-β-activated kinase 1 (Tak1) mediates agonist-induced Smad activation and linker region phosphorylation in embryonic craniofacial neural crest-derived cells. The Journal of Biological Chemistry. 288: 13467-80. PMID 23546880 DOI: 10.1074/Jbc.M112.431775  0.381
2013 Schulz TJ, Huang P, Huang TL, Xue R, McDougall LE, Townsend KL, Cypess AM, Mishina Y, Gussoni E, Tseng YH. Brown-fat paucity due to impaired BMP signalling induces compensatory browning of white fat. Nature. 495: 379-83. PMID 23485971 DOI: 10.1038/Nature11943  0.342
2013 Hojo H, Ohba S, Taniguchi K, Shirai M, Yano F, Saito T, Ikeda T, Nakajima K, Komiyama Y, Nakagata N, Suzuki K, Mishina Y, Yamada M, Konno T, Takato T, et al. Hedgehog-Gli activators direct osteo-chondrogenic function of bone morphogenetic protein toward osteogenesis in the perichondrium. The Journal of Biological Chemistry. 288: 9924-32. PMID 23423383 DOI: 10.1074/Jbc.M112.409342  0.513
2013 Sakaguchi M, Sharmin S, Taguchi A, Ohmori T, Fujimura S, Abe T, Kiyonari H, Komatsu Y, Mishina Y, Asashima M, Araki E, Nishinakamura R. The phosphatase Dullard negatively regulates BMP signalling and is essential for nephron maintenance after birth. Nature Communications. 4: 1398. PMID 23360989 DOI: 10.1038/Ncomms2408  0.432
2013 Komatsu Y, Yu PB, Kamiya N, Pan H, Fukuda T, Scott GJ, Ray MK, Yamamura K, Mishina Y. Augmentation of Smad-dependent BMP signaling in neural crest cells causes craniosynostosis in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 1422-33. PMID 23281127 DOI: 10.1002/Jbmr.1857  0.53
2012 Takaesu G, Inagaki M, Takubo K, Mishina Y, Hess PR, Dean GA, Yoshimura A, Matsumoto K, Suda T, Ninomiya-Tsuji J. TAK1 (MAP3K7) signaling regulates hematopoietic stem cells through TNF-dependent and -independent mechanisms. Plos One. 7: e51073. PMID 23226465 DOI: 10.1371/Journal.Pone.0051073  0.405
2012 Morioka S, Inagaki M, Komatsu Y, Mishina Y, Matsumoto K, Ninomiya-Tsuji J. TAK1 kinase signaling regulates embryonic angiogenesis by modulating endothelial cell survival and migration. Blood. 120: 3846-57. PMID 22972987 DOI: 10.1182/Blood-2012-03-416198  0.408
2012 Kua HY, Liu H, Leong WF, Li L, Jia D, Ma G, Hu Y, Wang X, Chau JF, Chen YG, Mishina Y, Boast S, Yeh J, Xia L, Chen GQ, et al. c-Abl promotes osteoblast expansion by differentially regulating canonical and non-canonical BMP pathways and p16INK4a expression. Nature Cell Biology. 14: 727-37. PMID 22729085 DOI: 10.1038/Ncb2528  0.423
2012 Kaku M, Komatsu Y, Mochida Y, Yamauchi M, Mishina Y, Ko CC. Identification and characterization of neural crest-derived cells in adult periodontal ligament of mice. Archives of Oral Biology. 57: 1668-75. PMID 22704955 DOI: 10.1016/J.Archoralbio.2012.04.022  0.339
2012 Liu HX, Komatsu Y, Mishina Y, Mistretta CM. Neural crest contribution to lingual mesenchyme, epithelium and developing taste papillae and taste buds. Developmental Biology. 368: 294-303. PMID 22659543 DOI: 10.1016/J.Ydbio.2012.05.028  0.396
2012 Chau JF, Jia D, Wang Z, Liu Z, Hu Y, Zhang X, Jia H, Lai KP, Leong WF, Au BJ, Mishina Y, Chen YG, Biondi C, Robertson E, Xie D, et al. A crucial role for bone morphogenetic protein-Smad1 signalling in the DNA damage response. Nature Communications. 3: 836. PMID 22588298 DOI: 10.1038/Ncomms1832  0.391
2012 Omori E, Inagaki M, Mishina Y, Matsumoto K, Ninomiya-Tsuji J. Epithelial transforming growth factor β-activated kinase 1 (TAK1) is activated through two independent mechanisms and regulates reactive oxygen species. Proceedings of the National Academy of Sciences of the United States of America. 109: 3365-70. PMID 22331902 DOI: 10.1073/Pnas.1116188109  0.396
2012 McNeill B, Perez-Iratxeta C, Mazerolle C, Furimsky M, Mishina Y, Andrade-Navarro MA, Wallace VA. Comparative genomics identification of a novel set of temporally regulated hedgehog target genes in the retina. Molecular and Cellular Neurosciences. 49: 333-40. PMID 22281533 DOI: 10.1016/J.Mcn.2011.12.008  0.39
2012 Liu HX, Grosse AS, Iwatsuki K, Mishina Y, Gumucio DL, Mistretta CM. Separate and distinctive roles for Wnt5a in tongue, lingual tissue and taste papilla development. Developmental Biology. 361: 39-56. PMID 22024319 DOI: 10.1016/J.Ydbio.2011.10.009  0.482
2011 Wang SK, Komatsu Y, Mishina Y. Potential contribution of neural crest cells to dental enamel formation. Biochemical and Biophysical Research Communications. 415: 114-9. PMID 22020075 DOI: 10.1016/J.Bbrc.2011.10.026  0.41
2011 Shu B, Zhang M, Xie R, Wang M, Jin H, Hou W, Tang D, Harris SE, Mishina Y, O'Keefe RJ, Hilton MJ, Wang Y, Chen D. BMP2, but not BMP4, is crucial for chondrocyte proliferation and maturation during endochondral bone development. Journal of Cell Science. 124: 3428-40. PMID 21984813 DOI: 10.1242/Jcs.083659  0.506
2011 Miura S, Mishina Y. Hepatocyte growth factor-regulated tyrosine kinase substrate (Hgs) is involved in BMP signaling through phosphorylation of SMADS and TAK1 in early mouse embryo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 2474-81. PMID 21953618 DOI: 10.1002/Dvdy.22750  0.449
2011 Kamiya N, Kaartinen VM, Mishina Y. Loss-of-function of ACVR1 in osteoblasts increases bone mass and activates canonical Wnt signaling through suppression of Wnt inhibitors SOST and DKK1. Biochemical and Biophysical Research Communications. 414: 326-30. PMID 21945937 DOI: 10.1016/J.Bbrc.2011.09.060  0.496
2011 Arao Y, Hamilton KJ, Ray MK, Scott G, Mishina Y, Korach KS. Estrogen receptor α AF-2 mutation results in antagonist reversal and reveals tissue selective function of estrogen receptor modulators. Proceedings of the National Academy of Sciences of the United States of America. 108: 14986-91. PMID 21873215 DOI: 10.1073/Pnas.1109180108  0.385
2011 Komatsu Y, Kaartinen V, Mishina Y. Cell cycle arrest in node cells governs ciliogenesis at the node to break left-right symmetry. Development (Cambridge, England). 138: 3915-20. PMID 21831921 DOI: 10.1242/Dev.068833  0.349
2011 Okamoto M, Murai J, Imai Y, Ikegami D, Kamiya N, Kato S, Mishina Y, Yoshikawa H, Tsumaki N. Conditional deletion of Bmpr1a in differentiated osteoclasts increases osteoblastic bone formation, increasing volume of remodeling bone in mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 26: 2511-22. PMID 21786321 DOI: 10.1002/Jbmr.477  0.411
2011 Di Giovanni V, Alday A, Chi L, Mishina Y, Rosenblum ND. Alk3 controls nephron number and androgen production via lineage-specific effects in intermediate mesoderm. Development (Cambridge, England). 138: 2717-27. PMID 21613322 DOI: 10.1242/Dev.059030  0.502
2011 Kamiya N, Mishina Y. New insights on the roles of BMP signaling in bone-A review of recent mouse genetic studies. Biofactors (Oxford, England). 37: 75-82. PMID 21488130 DOI: 10.1002/Biof.139  0.445
2011 Shimono K, Tung WE, Macolino C, Chi AH, Didizian JH, Mundy C, Chandraratna RA, Mishina Y, Enomoto-Iwamoto M, Pacifici M, Iwamoto M. Potent inhibition of heterotopic ossification by nuclear retinoic acid receptor-γ agonists. Nature Medicine. 17: 454-60. PMID 21460849 DOI: 10.1038/Nm.2334  0.441
2011 Maloum F, Allaire JM, Gagné-Sansfaçon J, Roy E, Belleville K, Sarret P, Morisset J, Carrier JC, Mishina Y, Kaestner KH, Perreault N. Epithelial BMP signaling is required for proper specification of epithelial cell lineages and gastric endocrine cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G1065-79. PMID 21415412 DOI: 10.1152/Ajpgi.00176.2010  0.471
2011 Domyan ET, Ferretti E, Throckmorton K, Mishina Y, Nicolis SK, Sun X. Signaling through BMP receptors promotes respiratory identity in the foregut via repression of Sox2. Development (Cambridge, England). 138: 971-81. PMID 21303850 DOI: 10.1242/Dev.053694  0.428
2011 Baek JA, Lan Y, Liu H, Maltby KM, Mishina Y, Jiang R. Bmpr1a signaling plays critical roles in palatal shelf growth and palatal bone formation. Developmental Biology. 350: 520-31. PMID 21185278 DOI: 10.1016/J.Ydbio.2010.12.028  0.511
2011 Bauler TJ, Kamiya N, Lapinski PE, Langewisch E, Mishina Y, Wilkinson JE, Feng GS, King PD. Development of severe skeletal defects in induced SHP-2-deficient adult mice: a model of skeletal malformation in humans with SHP-2 mutations. Disease Models & Mechanisms. 4: 228-39. PMID 21068439 DOI: 10.1242/Dmm.006130  0.465
2011 Ho CC, Zhou X, Mishina Y, Bernard DJ. Mechanisms of bone morphogenetic protein 2 (BMP2) stimulated inhibitor of DNA binding 3 (Id3) transcription. Molecular and Cellular Endocrinology. 332: 242-52. PMID 21056086 DOI: 10.1016/J.Mce.2010.10.019  0.404
2011 Komatsu Y, Yu P, Kamiya N, Mishina Y. Augmentation of Smad-dependent BMP signaling in cranial neural crests causes craniosynostosis in mice Developmental Biology. 356: 162. DOI: 10.1016/J.Ydbio.2011.05.600  0.43
2010 Ohyama T, Basch ML, Mishina Y, Lyons KM, Segil N, Groves AK. BMP signaling is necessary for patterning the sensory and nonsensory regions of the developing mammalian cochlea. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 15044-51. PMID 21068310 DOI: 10.1523/Jneurosci.3547-10.2010  0.432
2010 Shim M, Foley J, Anna C, Mishina Y, Eling T. Embryonic expression of cyclooxygenase-2 causes malformations in axial skeleton. The Journal of Biological Chemistry. 285: 16206-17. PMID 20236942 DOI: 10.1074/Jbc.M109.078576  0.427
2010 Miura S, Singh AP, Mishina Y. Bmpr1a is required for proper migration of the AVE through regulation of Dkk1 expression in the pre-streak mouse embryo. Developmental Biology. 341: 246-54. PMID 20211162 DOI: 10.1016/J.Ydbio.2010.02.038  0.448
2010 Hwang CH, Guo D, Harris MA, Howard O, Mishina Y, Gan L, Harris SE, Wu DK. Role of bone morphogenetic proteins on cochlear hair cell formation: analyses of Noggin and Bmp2 mutant mice. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 239: 505-13. PMID 20063299 DOI: 10.1002/Dvdy.22200  0.439
2010 Gordon J, Patel SR, Mishina Y, Manley NR. Evidence for an early role for BMP4 signaling in thymus and parathyroid morphogenesis. Developmental Biology. 339: 141-54. PMID 20043899 DOI: 10.1016/J.Ydbio.2009.12.026  0.47
2010 Kamiya N, Kobayashi T, Mochida Y, Yu PB, Yamauchi M, Kronenberg HM, Mishina Y. Wnt inhibitors Dkk1 and Sost are downstream targets of BMP signaling through the type IA receptor (BMPRIA) in osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 200-10. PMID 19874086 DOI: 10.1359/Jbmr.090806  0.514
2010 Shim M, Foley J, Anna C, Mishina Y, Eling TE. Abstract LB-338: Increased apoptosis and p53 expression in sclerotome of COX-2 transgenic embryo Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Lb-338  0.409
2010 Domyan ET, Mishina Y, Sun X. Signaling through BMP receptors promotes respiratory identity in the foregut through repression of SOX2 Developmental Biology. 344: 504. DOI: 10.1016/J.Ydbio.2010.05.326  0.425
2010 Mishina Y, Kaartinen V. Program/Abstract # 167BMP signaling through ACVR1 is crucial for establishment of the left–right asymmetry via proper formation of node cilia in the mouse Developmental Biology. 344. DOI: 10.1016/J.Ydbio.2010.05.208  0.335
2009 Morikawa Y, Zehir A, Maska E, Deng C, Schneider MD, Mishina Y, Cserjesi P. BMP signaling regulates sympathetic nervous system development through Smad4-dependent and -independent pathways. Development (Cambridge, England). 136: 3575-84. PMID 19793887 DOI: 10.1242/Dev.038133  0.49
2009 Rajagopal R, Huang J, Dattilo LK, Kaartinen V, Mishina Y, Deng CX, Umans L, Zwijsen A, Roberts AB, Beebe DC. The type I BMP receptors, Bmpr1a and Acvr1, activate multiple signaling pathways to regulate lens formation. Developmental Biology. 335: 305-16. PMID 19733164 DOI: 10.1016/J.Ydbio.2009.08.027  0.524
2009 Nomura-Kitabayashi A, Phoon CK, Kishigami S, Rosenthal J, Yamauchi Y, Abe K, Yamamura K, Samtani R, Lo CW, Mishina Y. Outflow tract cushions perform a critical valve-like function in the early embryonic heart requiring BMPRIA-mediated signaling in cardiac neural crest. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1617-28. PMID 19717734 DOI: 10.1152/Ajpheart.00304.2009  0.396
2009 Uchimura T, Komatsu Y, Tanaka M, McCann KL, Mishina Y. Bmp2 and Bmp4 genetically interact to support multiple aspects of mouse development including functional heart development. Genesis (New York, N.Y. : 2000). 47: 374-84. PMID 19391114 DOI: 10.1002/Dvg.20511  0.411
2009 Huang J, Dattilo LK, Rajagopal R, Liu Y, Kaartinen V, Mishina Y, Deng CX, Umans L, Zwijsen A, Roberts AB, Beebe DC. FGF-regulated BMP signaling is required for eyelid closure and to specify conjunctival epithelial cell fate. Development (Cambridge, England). 136: 1741-50. PMID 19369394 DOI: 10.1242/Dev.034082  0.546
2009 Scott GJ, Ray MK, Ward T, McCann K, Peddada S, Jiang FX, Mishina Y. Abnormal glucose metabolism in heterozygous mutant mice for a type I receptor required for BMP signaling. Genesis (New York, N.Y. : 2000). 47: 385-91. PMID 19358156 DOI: 10.1002/Dvg.20513  0.315
2009 Singh AP, Harada S, Mishina Y. Downstream genes of Sox8 that would affect adult male fertility. Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation. 3: 16-25. PMID 19339814 DOI: 10.1159/000200078  0.384
2009 Castranio T, Mishina Y. Bmp2 is required for cephalic neural tube closure in the mouse. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 110-22. PMID 19097048 DOI: 10.1002/Dvdy.21829  0.414
2009 Morikawa Y, Zehir A, Maska E, Deng C, Mishina Y, Cserjesi P. The regulation of sympathetic nervous system development by Smad4-dependent and -independent BMP pathways Developmental Biology. 331: 488. DOI: 10.1016/J.Ydbio.2009.05.382  0.391
2009 Masahisa Y, Kitamura N, Sahara N, Takashima A, Inoue H, Takahashi R, Mishina Y. BMP signaling through BMPIRA regulate gliosis in the sub-acute phase Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.439  0.33
2008 Yu PB, Deng DY, Lai CS, Hong CC, Cuny GD, Bouxsein ML, Hong DW, McManus PM, Katagiri T, Sachidanandan C, Kamiya N, Fukuda T, Mishina Y, Peterson RT, Bloch KD. BMP type I receptor inhibition reduces heterotopic [corrected] ossification. Nature Medicine. 14: 1363-9. PMID 19029982 DOI: 10.1038/Nm.1888  0.476
2008 Kamiya N, Ye L, Kobayashi T, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y. BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway. Development (Cambridge, England). 135: 3801-11. PMID 18927151 DOI: 10.1242/Dev.025825  0.459
2008 Inagaki M, Omori E, Kim JY, Komatsu Y, Scott G, Ray MK, Yamada G, Matsumoto K, Mishina Y, Ninomiya-Tsuji J. TAK1-binding protein 1, TAB1, mediates osmotic stress-induced TAK1 activation but is dispensable for TAK1-mediated cytokine signaling. The Journal of Biological Chemistry. 283: 33080-6. PMID 18829460 DOI: 10.1074/Jbc.M807574200  0.37
2008 Singh AP, Castranio T, Scott G, Guo D, Harris MA, Ray M, Harris SE, Mishina Y. Influences of reduced expression of maternal bone morphogenetic protein 2 on mouse embryonic development. Sexual Development : Genetics, Molecular Biology, Evolution, Endocrinology, Embryology, and Pathology of Sex Determination and Differentiation. 2: 134-41. PMID 18769073 DOI: 10.1159/000143431  0.43
2008 Inagaki M, Komatsu Y, Scott G, Yamada G, Ray M, Ninomiya-Tsuji J, Mishina Y. Generation of a conditional mutant allele for Tab1 in mouse. Genesis (New York, N.Y. : 2000). 46: 431-9. PMID 18693278 DOI: 10.1002/Dvg.20418  0.423
2008 Kamiya N, Ye L, Kobayashi T, Lucas DJ, Mochida Y, Yamauchi M, Kronenberg HM, Feng JQ, Mishina Y. Disruption of BMP signaling in osteoblasts through type IA receptor (BMPRIA) increases bone mass. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 23: 2007-17. PMID 18684091 DOI: 10.1359/Jbmr.080809  0.396
2008 El-Bizri N, Guignabert C, Wang L, Cheng A, Stankunas K, Chang CP, Mishina Y, Rabinovitch M. SM22alpha-targeted deletion of bone morphogenetic protein receptor 1A in mice impairs cardiac and vascular development, and influences organogenesis. Development (Cambridge, England). 135: 2981-91. PMID 18667463 DOI: 10.1242/Dev.017863  0.35
2008 Araya R, Kudo M, Kawano M, Ishii K, Hashikawa T, Iwasato T, Itohara S, Terasaki T, Oohira A, Mishina Y, Yamada M. BMP signaling through BMPRIA in astrocytes is essential for proper cerebral angiogenesis and formation of the blood-brain-barrier. Molecular and Cellular Neurosciences. 38: 417-30. PMID 18501628 DOI: 10.1016/J.Mcn.2008.04.003  0.421
2008 O'Bryan MK, Takada S, Kennedy CL, Scott G, Harada S, Ray MK, Dai Q, Wilhelm D, de Kretser DM, Eddy EM, Koopman P, Mishina Y. Sox8 is a critical regulator of adult Sertoli cell function and male fertility. Developmental Biology. 316: 359-70. PMID 18342849 DOI: 10.1016/J.Ydbio.2008.01.042  0.426
2008 Orvis GD, Jamin SP, Kwan KM, Mishina Y, Kaartinen VM, Huang S, Roberts AB, Umans L, Huylebroeck D, Zwijsen A, Wang D, Martin JF, Behringer RR. Functional redundancy of TGF-beta family type I receptors and receptor-Smads in mediating anti-Mullerian hormone-induced Mullerian duct regression in the mouse. Biology of Reproduction. 78: 994-1001. PMID 18322278 DOI: 10.1095/Biolreprod.107.066605  0.773
2008 Sun J, Chen H, Chen C, Whitsett JA, Mishina Y, Bringas P, Ma JC, Warburton D, Shi W. Prenatal lung epithelial cell-specific abrogation of Alk3-bone morphogenetic protein signaling causes neonatal respiratory distress by disrupting distal airway formation. The American Journal of Pathology. 172: 571-82. PMID 18258849 DOI: 10.2353/Ajpath.2008.070286  0.393
2008 Feng JQ, Scott G, Guo D, Jiang B, Harris M, Ward T, Ray M, Bonewald LF, Harris SE, Mishina Y. Generation of a conditional null allele for Dmp1 in mouse. Genesis (New York, N.Y. : 2000). 46: 87-91. PMID 18257058 DOI: 10.1002/Dvg.20370  0.384
2008 Hartwig S, Bridgewater D, Di Giovanni V, Cain J, Mishina Y, Rosenblum ND. BMP receptor ALK3 controls collecting system development Journal of the American Society of Nephrology. 19: 117-124. PMID 18178801 DOI: 10.1681/Asn.2007010080  0.441
2008 Stroud DM, Yu C, Fishman GI, Morley GE, Gaussin V, Burch JBE, Mishina Y, Schneider MD. Response to letters regarding article, "abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor" Circulation. 118: e107. DOI: 10.1161/Circulationaha.108.773457  0.37
2008 Mishina Y, Kaartinen V, Komatsu Y. BMP signaling through ACVR1 is crucial for establishment of the left–right asymmetry via proper formation of node cilia in the mouse Developmental Biology. 319: 585. DOI: 10.1016/J.Ydbio.2008.05.418  0.368
2008 Underwood S, Williams T, Mishina Y, Lewandoski M. In limb development BMP and FGF signaling interact through Sproutys Developmental Biology. 319: 498. DOI: 10.1016/J.Ydbio.2008.05.111  0.389
2007 Stroud DM, Gaussin V, Burch JB, Yu C, Mishina Y, Schneider MD, Fishman GI, Morley GE. Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor. Circulation. 116: 2535-43. PMID 17998461 DOI: 10.1161/Circulationaha.107.696583  0.394
2007 Kennedy CL, Koopman P, Mishina Y, O'Bryan MK. Sox8 and Sertoli-cell function. Annals of the New York Academy of Sciences. 1120: 104-13. PMID 17905940 DOI: 10.1196/Annals.1411.007  0.361
2007 Di-Gregorio A, Sancho M, Stuckey DW, Crompton LA, Godwin J, Mishina Y, Rodriguez TA. BMP signalling inhibits premature neural differentiation in the mouse embryo. Development (Cambridge, England). 134: 3359-69. PMID 17699604 DOI: 10.1242/Dev.005967  0.452
2007 Auclair BA, Benoit YD, Rivard N, Mishina Y, Perreault N. Bone Morphogenetic Protein Signaling Is Essential for Terminal Differentiation of the Intestinal Secretory Cell Lineage Gastroenterology. 133: 887-896. PMID 17678919 DOI: 10.1053/J.Gastro.2007.06.066  0.525
2007 Samanta J, Burke GM, McGuire T, Pisarek AJ, Mukhopadhyay A, Mishina Y, Kessler JA. BMPR1a signaling determines numbers of oligodendrocytes and calbindin-expressing interneurons in the cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 7397-407. PMID 17626200 DOI: 10.1523/Jneurosci.1434-07.2007  0.473
2007 Sun J, Liu YH, Chen H, Nguyen MP, Mishina Y, Upperman JS, Ford HR, Shi W. Deficient Alk3-mediated BMP signaling causes prenatal omphalocele-like defect. Biochemical and Biophysical Research Communications. 360: 238-43. PMID 17588538 DOI: 10.1016/J.Bbrc.2007.06.049  0.519
2007 Pajni-Underwood S, Wilson CP, Elder C, Mishina Y, Lewandoski M. BMP signals control limb bud interdigital programmed cell death by regulating FGF signaling. Development (Cambridge, England). 134: 2359-68. PMID 17537800 DOI: 10.1242/Dev.001677  0.452
2007 Miura S, Mishina Y. The DVE changes distal epiblast fate from definitive endoderm to neurectoderm by antagonizing nodal signaling Developmental Dynamics. 236: 1602-1610. PMID 17471538 DOI: 10.1002/Dvdy.21166  0.375
2007 Goulley J, Dahl U, Baeza N, Mishina Y, Edlund H. BMP4-BMPR1A Signaling in β Cells Is Required for and Augments Glucose-Stimulated Insulin Secretion Cell Metabolism. 5: 207-219. PMID 17339028 DOI: 10.1016/J.Cmet.2007.01.009  0.377
2007 Khalil IA, Kogure K, Futaki S, Hama S, Akita H, Ueno M, Kishida H, Kudoh M, Mishina Y, Kataoka K, Yamada M, Harashima H. Octaarginine-modified multifunctional envelope-type nanoparticles for gene delivery Gene Therapy. 14: 682-689. PMID 17268535 DOI: 10.1038/Sj.Gt.3302910  0.313
2007 Komatsu Y, Scott G, Nagy A, Kaartinen V, Mishina Y. BMP type I receptor ALK2 is essential for proper patterning at late gastrulation during mouse embryogenesis Developmental Dynamics. 236: 512-517. PMID 17117439 DOI: 10.1002/Dvdy.21021  0.418
2007 Song L, Fässler R, Mishina Y, Jiao K, Baldwin HS. Essential functions of Alk3 during AV cushion morphogenesis in mouse embryonic hearts. Developmental Biology. 301: 276-86. PMID 16959237 DOI: 10.1016/J.Ydbio.2006.08.004  0.49
2007 Underwood S, Mishina Y, Grieshammer U, Martin G, Williams T, Lewamdoski M. Genetic analysis of BMP-mediated cell survival in the limb bud mesenchyme Developmental Biology. 306: 342. DOI: 10.1016/J.Ydbio.2007.03.191  0.319
2006 Baek SJ, Okazaki R, Lee SH, Martinez J, Kim JS, Yamaguchi K, Mishina Y, Martin DW, Shoieb A, Mcentee MF, Eling TE. Nonsteroidal Anti-Inflammatory Drug-Activated Gene-1 Over Expression in Transgenic Mice Suppresses Intestinal Neoplasia Gastroenterology. 131: 1553-1560. PMID 17101328 DOI: 10.1053/J.Gastro.2006.09.015  0.364
2006 Yoon BS, Pogue R, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM. BMPs regulate multiple aspects of growth-plate chondrogenesis through opposing actions on FGF pathways Development. 133: 4667-4678. PMID 17065231 DOI: 10.1242/Dev.02680  0.619
2006 Zhang J, He XC, Tong WG, Johnson T, Wiedemann LM, Mishina Y, Feng JQ, Li L. Bone morphogenetic protein signaling inhibits hair follicle anagen induction by restricting epithelial stem/progenitor cell activation and expansion Stem Cells. 24: 2826-2839. PMID 16960130 DOI: 10.1634/Stemcells.2005-0544  0.493
2006 Miura S, Davis S, Klingensmith J, Mishina Y. BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of the somites Development. 133: 3767-3775. PMID 16943278 DOI: 10.1242/Dev.02552  0.503
2006 Park C, Lavine K, Mishina Y, Deng CX, Ornitz DM, Choi K. Bone morphogenetic protein receptor 1A signaling is dispensable for hematopoietic development but essential for vessel and atrioventricular endocardial cushion formation. Development (Cambridge, England). 133: 3473-84. PMID 16887829 DOI: 10.1242/Dev.02499  0.482
2006 Ovchinnikov DA, Selever J, Wang Y, Chen YT, Mishina Y, Martin JF, Behringer RR. BMP receptor type IA in limb bud mesenchyme regulates distal outgrowth and patterning. Developmental Biology. 295: 103-15. PMID 16630606 DOI: 10.1016/J.Ydbio.2006.03.013  0.817
2006 Fukuda T, Scott G, Komatsu Y, Araya R, Kawano M, Ray MK, Yamada M, Mishina Y. Generation of a mouse with conditionally activated signaling through the BMP receptor, ALK2. Genesis (New York, N.Y. : 2000). 44: 159-67. PMID 16604518 DOI: 10.1002/Dvg.20201  0.431
2006 Israelsson C, Lewén A, Kylberg A, Usoskin D, Althini S, Lindeberg J, Deng CX, Fukuda T, Wang Y, Kaartinen V, Mishina Y, Hillered L, Ebendal T. Genetically modified bone morphogenetic protein signalling alters traumatic brain injury-induced gene expression responses in the adult mouse. Journal of Neuroscience Research. 84: 47-57. PMID 16583403 DOI: 10.1002/Jnr.20856  0.432
2006 Kishigami S, Komatsu Y, Takeda H, Nomura-Kitabayashi A, Yamauchi Y, Abe K, Yamamura KI, Mishina Y. Optimized β-galactosidase staining method for simultaneous detection of endogenous gene expression in early mouse embryos Genesis. 44: 57-65. PMID 16419090 DOI: 10.1002/Gene.20186  0.312
2006 Eblaghie MC, Reedy M, Oliver T, Mishina Y, Hogan BL. Evidence that autocrine signaling through Bmpr1a regulates the proliferation, survival and morphogenetic behavior of distal lung epithelial cells. Developmental Biology. 291: 67-82. PMID 16414041 DOI: 10.1016/J.Ydbio.2005.12.006  0.453
2006 Pajni-Underwood S, Mishina Y, Williams T, Lewandoski M. BMP signaling is required for limb bud mesenchyme survival Developmental Biology. 295: 462. DOI: 10.1016/J.Ydbio.2006.04.423  0.386
2006 Castranio T, Mishina Y. Cephalic neural tube closure requires BMP2 expression Developmental Biology. 295: 446-447. DOI: 10.1016/J.Ydbio.2006.04.376  0.315
2006 Miura S, Davis S, Klingensmith J, Mishina Y. BMP signaling in the epiblast is required for proper recruitment of the prospective paraxial mesoderm and development of somites Developmental Biology. 295: 446. DOI: 10.1016/J.Ydbio.2006.04.374  0.439
2006 Komatsu Y, Fukuda T, Scott G, Kamiya N, Yamamura K, Mishina Y. Enhanced BMP signaling through a type I BMP receptor ALK2 shows ectopic cartilage formation in mouse craniofacial portion Developmental Biology. 295: 399. DOI: 10.1016/J.Ydbio.2006.04.223  0.494
2005 Gaussin V, Morley GE, Cox L, Zwijsen A, Vance KM, Emile L, Tian Y, Liu J, Hong C, Myers D, Conway SJ, Depre C, Mishina Y, Behringer RR, Hanks MC, et al. Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus. Circulation Research. 97: 219-26. PMID 16037571 DOI: 10.1161/01.Res.0000177862.85474.63  0.57
2005 Fukuda T, Mishina Y, Walker MP, DiAugustine RP. Conditional transgenic system for mouse aurora a kinase: degradation by the ubiquitin proteasome pathway controls the level of the transgenic protein. Molecular and Cellular Biology. 25: 5270-81. PMID 15923640 DOI: 10.1128/Mcb.25.12.5270-5281.2005  0.359
2005 Kishigami S, Mishina Y. BMP signaling and early embryonic patterning Cytokine and Growth Factor Reviews. 16: 265-278. PMID 15871922 DOI: 10.1016/J.Cytogfr.2005.04.002  0.452
2005 Yoon BS, Ovchinnikov DA, Yoshii I, Mishina Y, Behringer RR, Lyons KM. Bmpr1a and Bmpr1b have overlapping functions and are essential for chondrogenesis in vivo Proceedings of the National Academy of Sciences of the United States of America. 102: 5062-5067. PMID 15781876 DOI: 10.1073/Pnas.0500031102  0.757
2005 Liu W, Sun X, Braut A, Mishina Y, Behringer RR, Mina M, Martin JF. Distinct functions for Bmp signaling in lip and palate fusion in mice Development. 132: 1453-1461. PMID 15716346 DOI: 10.1242/Dev.01676  0.622
2005 Murali D, Yoshikawa S, Corrigan RR, Plas DJ, Crair MC, Oliver G, Lyons KM, Mishina Y, Furuta Y. Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development (Cambridge, England). 132: 913-23. PMID 15673568 DOI: 10.1242/Dev.01673  0.463
2005 Ye L, Mishina Y, Chen D, Huang H, Dallas SL, Dallas MR, Sivakumar P, Kunieda T, Tsutsui TW, Boskey A, Bonewald LF, Feng JQ. Dmp1-deficient mice display severe defects in cartilage formation responsible for a chondrodysplasia-like phenotype. The Journal of Biological Chemistry. 280: 6197-203. PMID 15590631 DOI: 10.1074/Jbc.M412911200  0.466
2004 Kishigami S, Yoshikawa SI, Castranio T, Okazaki K, Furuta Y, Mishina Y. BMP signaling through ACVRI is required for left-right patterning in the early mouse embryo Developmental Biology. 276: 185-193. PMID 15531373 DOI: 10.1016/J.Ydbio.2004.08.042  0.442
2004 Hu J, Chen YX, Wang D, Qi X, Li TG, Hao J, Mishina Y, Garbers DL, Zhao GQ. Developmental expression and function of Bmp4 in spermatogenesis and in maintaining epididymal integrity. Developmental Biology. 276: 158-71. PMID 15531371 DOI: 10.1016/J.Ydbio.2004.08.034  0.433
2004 Rountree RB, Schoor M, Chen H, Marks ME, Harley V, Mishina Y, Kingsley DM. BMP receptor signaling is required for postnatal maintenance of articular cartilage. Plos Biology. 2: e355. PMID 15492776 DOI: 10.1371/Journal.Pbio.0020355  0.467
2004 Wine-Lee L, Ahn KJ, Richardson RD, Mishina Y, Lyons KM, Crenshaw EB. Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development (Cambridge, England). 131: 5393-403. PMID 15469980 DOI: 10.1242/Dev.01379  0.44
2004 He XC, Zhang J, Tong WG, Tawfik O, Ross J, Scoville DH, Tian Q, Zeng X, He X, Wiedemann LM, Mishina Y, Li L. BMP signaling inhibits intestinal stem cell self-renewal through suppression of Wnt-β-catenin signaling Nature Genetics. 36: 1117-1121. PMID 15378062 DOI: 10.1038/Ng1430  0.437
2004 Stumpo DJ, Byrd NA, Phillips RS, Ghosh S, Maronpot RR, Castranio T, Meyers EN, Mishina Y, Blackshear PJ. Chorioallantoic fusion defects and embryonic lethality resulting from disruption of Zfp36L1, a gene encoding a CCCH tandem zinc finger protein of the Tristetraprolin family. Molecular and Cellular Biology. 24: 6445-55. PMID 15226444 DOI: 10.1128/Mcb.24.14.6445-6455.2004  0.377
2004 Oh H, Chi X, Bradfute SB, Mishina Y, Pocius J, Michael LH, Behringer RR, Schwartz RJ, Entman ML, Schneider MD. Cardiac muscle plasticity in adult and embryo by heart-derived progenitor cells. Annals of the New York Academy of Sciences. 1015: 182-9. PMID 15201159 DOI: 10.1196/Annals.1302.015  0.507
2004 Davis S, Miura S, Hill C, Mishina Y, Klingensmith J. BMP receptor IA is required in the mammalian embryo for endodermal morphogenesis and ectodermal patterning Developmental Biology. 270: 47-63. PMID 15136140 DOI: 10.1016/J.Ydbio.2004.01.048  0.496
2004 Andl T, Ahn K, Kairo A, Chu EY, Wine-Lee L, Reddy ST, Croft NJ, Cebra-Thomas JA, Metzger D, Chambon P, Lyons KM, Mishina Y, Seykora JT, Crenshaw EB, Millar SE. Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development. Development (Cambridge, England). 131: 2257-68. PMID 15102710 DOI: 10.1242/Dev.01125  0.489
2004 Mishina Y, Starbuck MW, Gentile MA, Fukuda T, Kasparcova V, Seedor JG, Hanks MC, Amling M, Pinero GJ, Harada SI, Behringer RR. Bone morphogenetic protein type IA receptor signaling regulates postnatal osteoblast function and bone remodeling Journal of Biological Chemistry. 279: 27560-27566. PMID 15090551 DOI: 10.1074/Jbc.M404222200  0.575
2004 Yuhki M, Yamada M, Kawano M, Iwasato T, Itohara S, Yoshida H, Ogawa M, Mishina Y. BMPR1A signaling is necessary for hair follicle cycling and hair shaft differentiation in mice. Development (Cambridge, England). 131: 1825-33. PMID 15084466 DOI: 10.1242/Dev.01079  0.498
2004 Qi X, Li TG, Hao J, Hu J, Wang J, Simmons H, Miura S, Mishina Y, Zhao GQ. BMP4 supports self-renewal of embryonic stem cells by inhibiting mitogen-activated protein kinase pathways. Proceedings of the National Academy of Sciences of the United States of America. 101: 6027-32. PMID 15075392 DOI: 10.1073/Pnas.0401367101  0.419
2004 Stottmann RW, Choi M, Mishina Y, Meyers EN, Klingensmith J. BMP receptor IA is required in mammalian neural crest cells for development of the cardiac outflow tract and ventricular myocardium. Development (Cambridge, England). 131: 2205-18. PMID 15073157 DOI: 10.1242/Dev.01086  0.436
2004 Ye L, MacDougall M, Zhang S, Xie Y, Zhang J, Li Z, Lu Y, Mishina Y, Feng JQ. Deletion of dentin matrix protein-1 leads to a partial failure of maturation of predentin into dentin, hypomineralization, and expanded cavities of pulp and root canal during postnatal tooth development. The Journal of Biological Chemistry. 279: 19141-8. PMID 14966118 DOI: 10.1074/Jbc.M400490200  0.401
2003 Jamin SP, Arango NA, Mishina Y, Hanks MC, Behringer RR. Genetic studies of the AMH/MIS signaling pathway for Müllerian duct regression Molecular and Cellular Endocrinology. 211: 15-19. PMID 14656471 DOI: 10.1016/J.Mce.2003.09.006  0.79
2003 Suzuki K, Bachiller D, Chen YPP, Kamikawa M, Ogi H, Haraguchi R, Ogino Y, Minami Y, Mishina Y, Ahn K, Crenshaw EB, Yamada G. Regulation of outgrowth and apoptosis for the terminal appendage: External genitalia: Development by concerted actions of BMP signaling Development. 130: 6209-6220. PMID 14602679 DOI: 10.1242/Dev.00846  0.491
2003 Zhang J, Niu C, Ye L, Huang H, He X, Tong WG, Ross J, Haug J, Johnson T, Feng JQ, Harris S, Wiedemann LM, Mishina Y, Li L. Identification of the haematopoietic stem cell niche and control of the niche size Nature. 425: 836-841. PMID 14574412 DOI: 10.1038/Nature02041  0.471
2003 Oh H, Bradfute SB, Gallardo TD, Nakamura T, Gaussin V, Mishina Y, Pocius J, Michael LH, Behringer RR, Garry DJ, Entman ML, Schneider MD. Cardiac progenitor cells from adult myocardium: Homing, differentiation, and fusion after infarction Proceedings of the National Academy of Sciences of the United States of America. 100: 12313-12318. PMID 14530411 DOI: 10.1073/Pnas.2132126100  0.505
2003 Feng JQ, Huang H, Lu Y, Ye L, Xie Y, Tsutsui TW, Kunieda T, Castranio T, Scott G, Bonewald LB, Mishina Y. The dentin matrix protein 1 (Dmp1) is specifically expressed in mineralized, but not soft, tissues during development Journal of Dental Research. 82: 776-780. PMID 14514755 DOI: 10.1177/154405910308201003  0.425
2003 Soshnikova N, Zechner D, Huelsken J, Mishina Y, Behringer RR, Taketo MM, Crenshaw EB, Birchmeier W. Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb. Genes & Development. 17: 1963-8. PMID 12923052 DOI: 10.1101/Gad.263003  0.575
2003 Sora I, Ikeda K, Mishina Y. Receptor knock-out and gene targeting. Generation of knock-out mice Methods in Molecular Medicine. 84: 205-216. PMID 12703325 DOI: 10.1385/1-59259-379-8:205  0.339
2003 Mishina Y. Function of bone morphogenetic protein signaling during mouse development Frontiers in Bioscience. 8: d855-d869. PMID 12700086 DOI: 10.2741/1097  0.47
2003 Takeuchi A, Mishina Y, Miyaishi O, Kojima E, Hasegawa T, Isobe Ki. Heterozygosity with respect to Zfp148 causes complete loss of fetal germ cells during mouse embryogenesis Nature Genetics. 33: 172-176. PMID 12524542 DOI: 10.1038/Ng1072  0.385
2003 Martinez G, Mishina Y, Bertram JF. BMPs and BMP receptors in mouse metanephric development: in vivo and in vitro studies. The International Journal of Developmental Biology. 46: 525-33. PMID 12141440  0.35
2002 Jamin SP, Arango NA, Mishina Y, Hanks MC, Behringer RR. Requirement of Bmpr1a for Müllerian duct regression during male sexual development Nature Genetics. 32: 408-410. PMID 12368913 DOI: 10.1038/Ng1003  0.796
2002 Hébert JM, Mishina Y, McConnell SK. BMP signaling is required locally to pattern the dorsal telencephalic midline. Neuron. 35: 1029-41. PMID 12354394 DOI: 10.1016/S0896-6273(02)00900-5  0.441
2002 Takeda H, Takami M, Oguni T, Tsuji T, Yoneda K, Sato H, Ihara N, Itoh T, Kata SR, Mishina Y, Womack JE, Moritomo Y, Sugimoto Y, Kunieda T. Positional cloning of the gene LIMBIN responsible for bovine chondrodysplastic dwarfism. Proceedings of the National Academy of Sciences of the United States of America. 99: 10549-54. PMID 12136126 DOI: 10.1073/Pnas.152337899  0.345
2002 Jamin SP, Arango NA, Mishina Y, Behringer RR. Genetic studies of MIS signalling in sexual development Novartis Foundation Symposium. 244: 157-168. PMID 11990789 DOI: 10.1002/0470868732.Ch13  0.785
2002 Mishina Y, Hanks MC, Miura S, Tallquist MD, Behringer RR. Generation of Bmpr/Alk3 conditional knockout mice Genesis. 32: 69-72. PMID 11857780 DOI: 10.1002/Gene.10038  0.468
2002 Gaussin V, Van de Putte T, Mishina Y, Hanks MC, Zwijsen A, Huylebroeck D, Behringer RR, Schneider MD. Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3. Proceedings of the National Academy of Sciences of the United States of America. 99: 2878-83. PMID 11854453 DOI: 10.1073/Pnas.042390499  0.588
1999 Mishina Y, Crombie R, Bradley A, Behringer RR. Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis. Developmental Biology. 213: 314-26. PMID 10479450 DOI: 10.1006/Dbio.1999.9378  0.617
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