Year |
Citation |
Score |
2019 |
Chen S, Kapilashrami K, Senevirathne C, Wang Z, Wang J, Linscott JA, Luo M. Substrate-differentiated Transition States of SET7/9-catalyzed Lysine Methylation. Journal of the American Chemical Society. PMID 31034218 DOI: 10.1021/Jacs.9B02553 |
0.343 |
|
2016 |
Abeysinghe T, Hong B, Wang Z, Kohen A. Preserved hydride transfer mechanism in evolutionarily divergent thymidylate synthases. Current Topics in Biochemical Research. 17: 19-30. PMID 28018055 |
0.677 |
|
2016 |
Linscott JA, Kapilashrami K, Wang Z, Senevirathne C, Bothwell IR, Blum G, Luo M. Kinetic isotope effects reveal early transition state of protein lysine methyltransferase SET8. Proceedings of the National Academy of Sciences of the United States of America. PMID 27940912 DOI: 10.1073/Pnas.1609032114 |
0.327 |
|
2016 |
Wang Z, Chang EP, Schramm VL. "Triple Isotope Effects Support Concerted Hydride and Proton Transfer and Promoting Vibrations in Human Heart Lactate Dehydrogenase". Journal of the American Chemical Society. PMID 27766841 DOI: 10.1021/Jacs.6B09049 |
0.567 |
|
2016 |
Du Q, Wang Z, Schramm VL. Human DNMT1 transition state structure. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929335 DOI: 10.1073/Pnas.1522491113 |
0.512 |
|
2015 |
Wang Z, Antoniou D, Schwartz SD, Schramm VL. "Hydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects and Heavy Enzyme Studies". Biochemistry. PMID 26652185 DOI: 10.1021/Acs.Biochem.5B01241 |
0.59 |
|
2015 |
Hong B, Li C, Wang Z, Chen J, Li H, Lei X. Enantioselective Total Synthesis of (-)-Incarviatone A. Journal of the American Chemical Society. 137: 11946-9. PMID 26371964 DOI: 10.1021/Jacs.5B08551 |
0.497 |
|
2014 |
Wang Z, Singh P, Czekster CM, Kohen A, Schramm VL. Protein mass-modulated effects in the catalytic mechanism of dihydrofolate reductase: beyond promoting vibrations. Journal of the American Chemical Society. 136: 8333-41. PMID 24820793 DOI: 10.1021/Ja501936D |
0.665 |
|
2013 |
Wang Z, Sapienza PJ, Abeysinghe T, Luzum C, Lee AL, Finer-Moore JS, Stroud RM, Kohen A. Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. Journal of the American Chemical Society. 135: 7583-92. PMID 23611499 DOI: 10.1021/Ja400761X |
0.572 |
|
2013 |
Wang Z, Ferrer S, Moliner V, Kohen A. QM/MM calculations suggest a novel intermediate following the proton abstraction catalyzed by thymidylate synthase. Biochemistry. 52: 2348-58. PMID 23464672 DOI: 10.1021/Bi400267Q |
0.612 |
|
2012 |
Wang Z, Abeysinghe T, Finer-Moore JS, Stroud RM, Kohen A. A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase. Journal of the American Chemical Society. 134: 17722-30. PMID 23034004 DOI: 10.1021/Ja307859M |
0.602 |
|
2012 |
Wang Z, Roston D, Kohen A. Experimental and theoretical studies of enzyme-catalyzed hydrogen-transfer reactions. Advances in Protein Chemistry and Structural Biology. 87: 155-80. PMID 22607755 DOI: 10.1016/B978-0-12-398312-1.00006-8 |
0.702 |
|
2010 |
Wang Z, Kohen A. Thymidylate synthase catalyzed H-transfers: two chapters in one tale. Journal of the American Chemical Society. 132: 9820-5. PMID 20575541 DOI: 10.1021/Ja103010B |
0.608 |
|
2009 |
Wang Z, Chernyshev A, Koehn EM, Manuel TD, Lesley SA, Kohen A. Oxidase activity of a flavin-dependent thymidylate synthase. The Febs Journal. 276: 2801-10. PMID 19459936 DOI: 10.1111/J.1742-4658.2009.07003.X |
0.673 |
|
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