Zhen Wang - Publications

Albert Einstein College of Medicine, New York, New York, United States 
Enzyme Catalysis; Protein Dynamics; Transition State Analysis

12 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any innacuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Wang X, Du Q, Mao Z, Fan X, Hu B, Wang Z, Chen Z, Jiang X, Wang Z, Lei N, Wang H, Zhu Y. Combined treatment with artesunate and bromocriptine has synergistic anticancer effects in pituitary adenoma cell lines. Oncotarget. PMID 28501857 DOI: 10.18632/oncotarget.17437  0.56
2016 Abeysinghe T, Hong B, Wang Z, Kohen A. Preserved hydride transfer mechanism in evolutionarily divergent thymidylate synthases. Current Topics in Biochemical Research. 17: 19-30. PMID 28018055  1
2016 Wang Z, Chang EP, Schramm VL. "Triple Isotope Effects Support Concerted Hydride and Proton Transfer and Promoting Vibrations in Human Heart Lactate Dehydrogenase". Journal of the American Chemical Society. PMID 27766841 DOI: 10.1021/jacs.6b09049  0.56
2016 Du Q, Wang Z, Schramm VL. Human DNMT1 transition state structure. Proceedings of the National Academy of Sciences of the United States of America. PMID 26929335 DOI: 10.1073/pnas.1522491113  0.56
2015 Wang Z, Antoniou D, Schwartz SD, Schramm VL. "Hydride Transfer in DHFR by Transition Path Sampling, Kinetic Isotope Effects and Heavy Enzyme Studies". Biochemistry. PMID 26652185 DOI: 10.1021/acs.biochem.5b01241  0.52
2014 Wang Z, Singh P, Czekster CM, Kohen A, Schramm VL. Protein mass-modulated effects in the catalytic mechanism of dihydrofolate reductase: beyond promoting vibrations. Journal of the American Chemical Society. 136: 8333-41. PMID 24820793 DOI: 10.1021/ja501936d  0.52
2013 Wang Z, Sapienza PJ, Abeysinghe T, Luzum C, Lee AL, Finer-Moore JS, Stroud RM, Kohen A. Mg2+ binds to the surface of thymidylate synthase and affects hydride transfer at the interior active site. Journal of the American Chemical Society. 135: 7583-92. PMID 23611499 DOI: 10.1021/ja400761x  1
2013 Wang Z, Ferrer S, Moliner V, Kohen A. QM/MM calculations suggest a novel intermediate following the proton abstraction catalyzed by thymidylate synthase. Biochemistry. 52: 2348-58. PMID 23464672 DOI: 10.1021/bi400267q  1
2012 Wang Z, Abeysinghe T, Finer-Moore JS, Stroud RM, Kohen A. A remote mutation affects the hydride transfer by disrupting concerted protein motions in thymidylate synthase. Journal of the American Chemical Society. 134: 17722-30. PMID 23034004 DOI: 10.1021/ja307859m  1
2012 Wang Z, Roston D, Kohen A. Experimental and theoretical studies of enzyme-catalyzed hydrogen-transfer reactions. Advances in Protein Chemistry and Structural Biology. 87: 155-80. PMID 22607755 DOI: 10.1016/B978-0-12-398312-1.00006-8  1
2010 Wang Z, Kohen A. Thymidylate synthase catalyzed H-transfers: two chapters in one tale. Journal of the American Chemical Society. 132: 9820-5. PMID 20575541 DOI: 10.1021/ja103010b  1
2009 Wang Z, Chernyshev A, Koehn EM, Manuel TD, Lesley SA, Kohen A. Oxidase activity of a flavin-dependent thymidylate synthase. The Febs Journal. 276: 2801-10. PMID 19459936 DOI: 10.1111/j.1742-4658.2009.07003.x  1
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