| Year |
Citation |
Score |
| 2023 |
Zhang S, Zhang L, Greule A, Tailhades J, Marschall E, Prasongpholchai P, Leng DJ, Zhang J, Zhu J, Kaczmarski JA, Schittenhelm RB, Einsle O, Jackson CJ, Alberti F, Bechthold A, et al. P450-mediated dehydrotyrosine formation during WS9326 biosynthesis proceeds dehydrogenation of a specific acylated dipeptide substrate. Acta Pharmaceutica Sinica. B. 13: 3561-3574. PMID 37655329 DOI: 10.1016/j.apsb.2023.03.021 |
0.741 |
|
| 2023 |
Ho YTC, Kaczmarski JA, Tailhades J, Izoré T, Steer DL, Schittenhelm RB, Tosin M, Jackson CJ, Cryle MJ. Not always an innocent bystander: the impact of stabilised phosphopantetheine moieties when studying nonribosomal peptide biosynthesis. Chemical Communications (Cambridge, England). PMID 37310188 DOI: 10.1039/d3cc01578e |
0.749 |
|
| 2022 |
East NJ, Clifton BE, Jackson CJ, Kaczmarski JA. The role of oligomerization in the optimization of cyclohexadienyl dehydratase conformational dynamics and catalytic activity. Protein Science : a Publication of the Protein Society. e4510. PMID 36382881 DOI: 10.1002/pro.4510 |
0.761 |
|
| 2022 |
Joho Y, Vongsouthi V, Spence MA, Ton J, Gomez C, Tan LL, Kaczmarski JA, Caputo AT, Royan S, Jackson CJ, Ardevol A. Ancestral Sequence Reconstruction Identifies Structural Changes Underlying the Evolution of PETase and Variants with Improved Stability and Activity. Biochemistry. PMID 35951410 DOI: 10.1021/acs.biochem.2c00323 |
0.753 |
|
| 2022 |
Ergun Ayva C, Fiorito MM, Guo Z, Edwardraja S, Kaczmarski JA, Gagoski D, Walden P, Johnston WA, Jackson CJ, Nebl T, Alexandrov K. Exploring Performance Parameters of Artificial Allosteric Protein Switches. Journal of Molecular Biology. 167678. PMID 35709893 DOI: 10.1016/j.jmb.2022.167678 |
0.762 |
|
| 2021 |
Gade M, Tan LL, Damry AM, Sandhu M, Brock JS, Delaney A, Villar-Briones A, Jackson CJ, Laurino P. Substrate Dynamics Contribute to Enzymatic Specificity in Human and Bacterial Methionine Adenosyltransferases. Jacs Au. 1: 2349-2360. PMID 34977903 DOI: 10.1021/jacsau.1c00464 |
0.3 |
|
| 2021 |
Ford DJ, Duggan NM, Fry SE, Ripoll-Rozada J, Agten SM, Liu W, Corcilius L, Hackeng TM, van Oerle R, Spronk HMH, Ashhurst AS, Mini Sasi V, Kaczmarski JA, Jackson CJ, Pereira PJB, et al. Potent Cyclic Peptide Inhibitors of FXIIa Discovered by mRNA Display with Genetic Code Reprogramming. Journal of Medicinal Chemistry. PMID 34044534 DOI: 10.1021/acs.jmedchem.1c00651 |
0.733 |
|
| 2021 |
Spence MA, Kaczmarski JA, Saunders JW, Jackson CJ. Ancestral sequence reconstruction for protein engineers. Current Opinion in Structural Biology. 69: 131-141. PMID 34023793 DOI: 10.1016/j.sbi.2021.04.001 |
0.734 |
|
| 2021 |
Izoré T, Candace Ho YT, Kaczmarski JA, Gavriilidou A, Chow KH, Steer DL, Goode RJA, Schittenhelm RB, Tailhades J, Tosin M, Challis GL, Krenske EH, Ziemert N, Jackson CJ, Cryle MJ. Structures of a non-ribosomal peptide synthetase condensation domain suggest the basis of substrate selectivity. Nature Communications. 12: 2511. PMID 33947858 DOI: 10.1038/s41467-021-22623-0 |
0.764 |
|
| 2021 |
Damry AM, Jackson CJ. The evolution and engineering of enzyme activity through tuning conformational landscapes. Protein Engineering, Design & Selection : Peds. 34. PMID 33903911 DOI: 10.1093/protein/gzab009 |
0.33 |
|
| 2021 |
Chatterjee D, Lewis FJ, Sutton HJ, Kaczmarski JA, Gao X, Cai Y, McNamara HA, Jackson CJ, Cockburn IA. Avid binding by B cells to the Plasmodium circumsporozoite protein repeat suppresses responses to protective subdominant epitopes. Cell Reports. 35: 108996. PMID 33852850 DOI: 10.1016/j.celrep.2021.108996 |
0.726 |
|
| 2020 |
Kaczmarski JA, Mahawaththa MC, Feintuch A, Clifton BE, Adams LA, Goldfarb D, Otting G, Jackson CJ. Altered conformational sampling along an evolutionary trajectory changes the catalytic activity of an enzyme. Nature Communications. 11: 5945. PMID 33230119 DOI: 10.1038/s41467-020-19695-9 |
0.771 |
|
| 2020 |
Hendler A, Akiva E, Sandhu M, Goldberg D, Arbely E, Jackson CJ, Aharoni A. Human SIRT1 multi-specificity is modulated by active-site vicinity substitutions during natural evolution. Molecular Biology and Evolution. PMID 32956445 DOI: 10.1093/Molbev/Msaa244 |
0.444 |
|
| 2020 |
Esquirol L, Peat TS, Sugrue E, Balotra S, Rottet S, Warden AC, Wilding M, Hartley CJ, Jackson CJ, Newman J, Scott C. Bacterial catabolism of s-triazine herbicides: biochemistry, evolution and application. Advances in Microbial Physiology. 76: 129-186. PMID 32408946 DOI: 10.1016/Bs.Ampbs.2020.01.004 |
0.344 |
|
| 2020 |
Li D, Damry AM, Petrie JR, Vanhercke T, Singh S, Jackson CJ. Consensus mutagenesis and ancestral reconstruction provide insight into the substrate specificity and evolution of the front-end Δ6-desaturase family. Biochemistry. PMID 32208646 DOI: 10.1021/Acs.Biochem.0C00110 |
0.403 |
|
| 2020 |
Chandler PG, Broendum SS, Riley BT, Spence MA, Jackson CJ, McGowan S, Buckle AM. Strategies for Increasing Protein Stability. Methods in Molecular Biology (Clifton, N.J.). 2073: 163-181. PMID 31612442 DOI: 10.1007/978-1-4939-9869-2_10 |
0.355 |
|
| 2019 |
Rapson TD, Christley-Balcomb AM, Jackson CJ, Sutherland TD. Enhancement of metallomacrocycle-based oxygen reduction catalysis through immobilization in a tunable silk-protein scaffold. Journal of Inorganic Biochemistry. 204: 110960. PMID 31865257 DOI: 10.1016/J.Jinorgbio.2019.110960 |
0.303 |
|
| 2019 |
Kaczmarski JA, Hong N, Mukherjee B, Wey LT, Rourke L, Förster B, Peat TS, Price GD, Jackson CJ. Structural basis for the allosteric regulation of the SbtA bicarbonate transporter by the P-like protein, SbtB, from sp. PCC7001. Biochemistry. PMID 31746199 DOI: 10.1021/Acs.Biochem.9B00880 |
0.758 |
|
| 2019 |
Yang G, Anderson DW, Baier F, Dohmen E, Hong N, Carr PD, Kamerlin SCL, Jackson CJ, Bornberg-Bauer E, Tokuriki N. Higher-order epistasis shapes the fitness landscape of a xenobiotic-degrading enzyme. Nature Chemical Biology. 15: 1120-1128. PMID 31636435 DOI: 10.1038/S41589-019-0386-3 |
0.391 |
|
| 2019 |
Zhang W, Carter B, Day G, Govan N, Jackson CJ, Perriman AW. Sequential electrostatic assembly of a polymer surfactant corona increases activity of the phosphotriesterase arPTE. Bioconjugate Chemistry. PMID 31603664 DOI: 10.1021/Acs.Bioconjchem.9B00664 |
0.306 |
|
| 2019 |
Greule A, Izoré T, Iftime D, Tailhades J, Schoppet M, Zhao Y, Peschke M, Ahmed I, Kulik A, Adamek M, Goode RJA, Schittenhelm RB, Kaczmarski JA, Jackson CJ, Ziemert N, et al. Kistamicin biosynthesis reveals the biosynthetic requirements for production of highly crosslinked glycopeptide antibiotics. Nature Communications. 10: 2613. PMID 31197182 DOI: 10.1038/S41467-019-10384-W |
0.766 |
|
| 2019 |
Bashiri G, Antoney J, Jirgis ENM, Shah MV, Ney B, Copp J, Stuteley SM, Sreebhavan S, Palmer B, Middleditch M, Tokuriki N, Greening C, Scott C, Baker EN, Jackson CJ. A revised biosynthetic pathway for the cofactor F in prokaryotes. Nature Communications. 10: 1558. PMID 30952857 DOI: 10.1038/S41467-019-09534-X |
0.32 |
|
| 2019 |
Wilding M, Hong N, Spence M, Buckle AM, Jackson CJ. Protein engineering: the potential of remote mutations. Biochemical Society Transactions. PMID 30902926 DOI: 10.1042/Bst20180614 |
0.38 |
|
| 2019 |
Kaczmarski JA, Mitchell JA, Spence MA, Vongsouthi V, Jackson CJ. Structural and evolutionary approaches to the design and optimization of fluorescence-based small molecule biosensors. Current Opinion in Structural Biology. 57: 31-38. PMID 30825845 DOI: 10.1016/J.Sbi.2019.01.013 |
0.729 |
|
| 2019 |
Baier F, Hong N, Yang G, Pabis A, Miton CM, Barrozo A, Carr PD, Kamerlin SC, Jackson CJ, Tokuriki N. Cryptic genetic variation shapes the adaptive evolutionary potential of enzymes. Elife. 8. PMID 30719972 DOI: 10.7554/Elife.40789 |
0.363 |
|
| 2019 |
Izoré T, Tailhades J, Hansen MH, Kaczmarski JA, Jackson CJ, Cryle MJ. nonribosomal peptide synthetase Ebony encodes an atypical condensation domain. Proceedings of the National Academy of Sciences of the United States of America. PMID 30705105 DOI: 10.1073/Pnas.1811194116 |
0.764 |
|
| 2019 |
Hopkins DH, Rane RV, Younus F, Coppin CW, Pandey G, Jackson CJ, Oakeshott JG. The molecular basis for the neofunctionalization of the juvenile hormone esterase duplication in Drosophila. Insect Biochemistry and Molecular Biology. PMID 30611903 DOI: 10.1016/J.Ibmb.2019.01.001 |
0.399 |
|
| 2019 |
Shah MV, Antoney J, Kang SW, Warden AC, Hartley CJ, Nazem-Bokaee H, Jackson CJ, Scott C. Cofactor F420-dependent enzymes: An under-explored resource for asymmetric redox biocatalysis Catalysts. 9: 868. DOI: 10.3390/Catal9100868 |
0.308 |
|
| 2018 |
Harold LK, Antoney J, Ahmed FH, Hards K, Carr PD, Rapson T, Greening C, Jackson CJ, Cook GM. FAD-sequestering proteins protect mycobacteria against hypoxic and oxidative stress. The Journal of Biological Chemistry. PMID 30567740 DOI: 10.1074/Jbc.Ra118.006237 |
0.344 |
|
| 2018 |
Hong NS, Petrović D, Lee R, Gryn'ova G, Purg M, Saunders J, Bauer P, Carr PD, Lin CY, Mabbitt PD, Zhang W, Altamore T, Easton C, Coote ML, Kamerlin SCL, ... Jackson CJ, et al. The evolution of multiple active site configurations in a designed enzyme. Nature Communications. 9: 3900. PMID 30254369 DOI: 10.1038/S41467-018-06305-Y |
0.398 |
|
| 2018 |
Clifton BE, Kaczmarski JA, Carr PD, Gerth ML, Tokuriki N, Jackson CJ. Evolution of cyclohexadienyl dehydratase from an ancestral solute-binding protein. Nature Chemical Biology. PMID 29686357 DOI: 10.1038/S41589-018-0043-2 |
0.781 |
|
| 2017 |
Campbell EC, Correy GJ, Mabbitt PD, Buckle AM, Tokiriki N, Jackson CJ. Laboratory evolution of protein conformational dynamics. Current Opinion in Structural Biology. 50: 49-57. PMID 29120734 DOI: 10.1016/J.Sbi.2017.09.005 |
0.346 |
|
| 2017 |
Ney B, Carere CR, Sparling R, Jirapanjawat T, Stott MB, Jackson CJ, Oakeshott JG, Warden AC, Greening C. Cofactor Tail Length Modulates Catalysis of Bacterial F420-Dependent Oxidoreductases. Frontiers in Microbiology. 8: 1902. PMID 29021791 DOI: 10.3389/Fmicb.2017.01902 |
0.315 |
|
| 2017 |
Hopkins DH, Fraser NJ, Mabbitt PD, Carr PD, Oakeshott JG, Jackson CJ. The structure of an insecticide sequestering carboxylesterase from the disease vector Culex quinquefasciatus: what makes an enzyme a good insecticide sponge? Biochemistry. PMID 28929747 DOI: 10.1021/Acs.Biochem.7B00774 |
0.378 |
|
| 2017 |
Fisher CR, Sutton HJ, Kaczmarski JA, McNamara HA, Clifton B, Mitchell J, Cai Y, Dups JN, D'Arcy NJ, Singh M, Chuah A, Peat TS, Jackson CJ, Cockburn IA. T-dependent B cell responses to Plasmodium induce antibodies that form a high-avidity multivalent complex with the circumsporozoite protein. Plos Pathogens. 13: e1006469. PMID 28759640 DOI: 10.1371/Journal.Ppat.1006469 |
0.733 |
|
| 2017 |
Greening C, Jirapanjawat T, Afroze S, Ney B, Scott C, Pandey G, Lee BM, Russell RJ, Jackson CJ, Oakeshott JG, Taylor MC, Warden AC. Mycobacterial F420H2-Dependent Reductases Promiscuously Reduce Diverse Compounds through a Common Mechanism. Frontiers in Microbiology. 8: 1000. PMID 28620367 DOI: 10.3389/Fmicb.2017.01000 |
0.356 |
|
| 2017 |
Rouet R, Langley DB, Schofield P, Christie M, Roome B, Porebski BT, Buckle AM, Clifton BE, Jackson CJ, Stock D, Christ D. Structural reconstruction of protein ancestry. Proceedings of the National Academy of Sciences of the United States of America. PMID 28356519 DOI: 10.1073/Pnas.1613477114 |
0.367 |
|
| 2017 |
Mitchell JA, Zhang WH, Herde MK, Henneberger C, Janovjak H, O'Mara ML, Jackson CJ. Method for Developing Optical Sensors Using a Synthetic Dye-Fluorescent Protein FRET Pair and Computational Modeling and Assessment. Methods in Molecular Biology (Clifton, N.J.). 1596: 89-99. PMID 28293882 DOI: 10.1007/978-1-4939-6940-1_6 |
0.331 |
|
| 2017 |
Clifton BE, Whitfield JH, Sanchez-Romero I, Herde MK, Henneberger C, Janovjak H, Jackson CJ. Ancestral Protein Reconstruction and Circular Permutation for Improving the Stability and Dynamic Range of FRET Sensors. Methods in Molecular Biology (Clifton, N.J.). 1596: 71-87. PMID 28293881 DOI: 10.1007/978-1-4939-6940-1_5 |
0.312 |
|
| 2017 |
Sugrue E, Scott C, Jackson CJ. Constrained evolution of a bispecific enzyme: lessons for biocatalyst design. Organic & Biomolecular Chemistry. PMID 28054091 DOI: 10.1039/C6Ob02355J |
0.408 |
|
| 2016 |
Mohamed AE, Condic-Jurkic K, Ahmed FH, Yuan P, O'Mara ML, Jackson CJ, Coote ML. Hydrophobic Shielding Drives Catalysis of Hydride Transfer in a Family of F420H2-Dependent Enzymes. Biochemistry. 55: 6908-6918. PMID 27951661 DOI: 10.1021/Acs.Biochem.6B00683 |
0.372 |
|
| 2016 |
Sugrue E, Carr PD, Scott C, Jackson CJ. Active site desolvation and thermostability tradeoffs in the evolution of catalytically diverse triazine hydrolases. Biochemistry. PMID 27768291 DOI: 10.1021/Acs.Biochem.6B00731 |
0.416 |
|
| 2016 |
Li D, Moorman R, Vanhercke T, Petrie J, Singh S, Jackson CJ. Classification and substrate head-group specificity of membrane fatty acid desaturases. Computational and Structural Biotechnology Journal. 14: 341-349. PMID 27708750 DOI: 10.1016/J.Csbj.2016.08.003 |
0.33 |
|
| 2016 |
Purg M, Pabis A, Baier F, Tokuriki N, Jackson C, Kamerlin SC. Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase. Philosophical Transactions. Series a, Mathematical, Physical, and Engineering Sciences. 374. PMID 27698033 DOI: 10.1098/Rsta.2016.0150 |
0.329 |
|
| 2016 |
Campbell E, Kaltenbach M, Correy GJ, Carr PD, Porebski BT, Livingstone EK, Afriat-Jurnou L, Buckle AM, Weik M, Hollfelder F, Tokuriki N, Jackson CJ. The role of protein dynamics in the evolution of new enzyme function. Nature Chemical Biology. PMID 27618189 DOI: 10.1038/Nchembio.2175 |
0.428 |
|
| 2016 |
Yang G, Hong N, Baier F, Jackson CJ, Tokuriki N. Conformational tinkering drives evolution of a promiscuous activity through indirect mutational effects. Biochemistry. PMID 27444875 DOI: 10.1021/Acs.Biochem.6B00561 |
0.349 |
|
| 2016 |
Ahmed FH, Mohamed AE, Carr PD, Lee BM, Condic-Jurkic K, O'Mara ML, Jackson CJ. Rv2074 is a novel F420 H2 -dependent biliverdin reductase in Mycobacterium tuberculosis. Protein Science : a Publication of the Protein Society. PMID 27364382 DOI: 10.1002/Pro.2975 |
0.306 |
|
| 2016 |
Correy GJ, Carr PD, Meirelles T, Mabbitt PD, Fraser NJ, Weik M, Jackson CJ. Mapping the Accessible Conformational Landscape of an Insect Carboxylesterase Using Conformational Ensemble Analysis and Kinetic Crystallography. Structure (London, England : 1993). PMID 27210287 DOI: 10.1016/J.Str.2016.04.009 |
0.421 |
|
| 2016 |
Greening C, Ahmed FH, Mohamed AE, Lee BM, Pandey G, Warden AC, Scott C, Oakeshott JG, Taylor MC, Jackson CJ. Physiology, Biochemistry, and Applications of F420- and Fo-Dependent Redox Reactions. Microbiology and Molecular Biology Reviews : Mmbr. 80: 451-93. PMID 27122598 DOI: 10.1128/Mmbr.00070-15 |
0.315 |
|
| 2016 |
Fraser NJ, Liu JW, Mabbitt PD, Correy G, Coppin CW, Lethier M, Perugini MA, Murphy JM, Oakeshott JG, Weik M, Jackson CJ. Evolution of protein quaternary structure in response to selective pressure for increased thermostability. Journal of Molecular Biology. PMID 27016206 DOI: 10.1016/J.Jmb.2016.03.014 |
0.38 |
|
| 2016 |
Mabbitt PD, Correy GJ, Meirelles T, Fraser NJ, Coote ML, Jackson CJ. Conformational Disorganization within the Active Site of a Recently Evolved Organophosphate Hydrolase Limits Its Catalytic Efficiency Biochemistry. 55: 1408-1417. PMID 26881849 DOI: 10.1021/Acs.Biochem.5B01322 |
0.403 |
|
| 2016 |
Mohamed AE, Ahmed FH, Arulmozhiraja S, Lin CY, Taylor MC, Krausz ER, Jackson CJ, Coote ML. Protonation state of F420H2 in the prodrug-activating deazaflavin dependent nitroreductase (Ddn) from Mycobacterium tuberculosis. Molecular Biosystems. PMID 26876228 DOI: 10.1039/C6Mb00033A |
0.306 |
|
| 2016 |
Clifton BE, Jackson CJ. Ancestral Protein Reconstruction Yields Insights into Adaptive Evolution of Binding Specificity in Solute-Binding Proteins. Cell Chemical Biology. PMID 26853627 DOI: 10.1016/J.Chembiol.2015.12.010 |
0.375 |
|
| 2016 |
Sugrue E, Hartley CJ, Scott C, Jackson CJ. The Evolution of New Catalytic Mechanisms for Xenobiotic Hydrolysis in Bacterial Metalloenzymes Australian Journal of Chemistry. 69: 1383-1395. DOI: 10.1071/Ch16426 |
0.395 |
|
| 2015 |
Riley BT, Broendum SS, Reboul CF, Cowieson NP, Costa MG, Kass I, Jackson C, Perahia D, Buckle AM, McGowan S. Dynamic Motion and Communication in the Streptococcal C1 Phage Lysin, PlyC. Plos One. 10: e0140219. PMID 26470022 DOI: 10.1371/Journal.Pone.0140219 |
0.394 |
|
| 2015 |
Ahmed FH, Carr PD, Lee BM, Afriat-Jurnou L, Mohamed AE, Hong NS, Flanagan J, Taylor MC, Greening C, Jackson CJ. Sequence-Structure-Function Classification of a Catalytically Diverse Oxidoreductase Superfamily in Mycobacteria. Journal of Molecular Biology. PMID 26434506 DOI: 10.1016/J.Jmb.2015.09.021 |
0.4 |
|
| 2015 |
Kaltenbach M, Jackson CJ, Campbell EC, Hollfelder F, Tokuriki N. Reverse evolution leads to genotypic incompatibility despite functional and active-site convergence. Elife. 4. PMID 26274563 DOI: 10.7554/Elife.06492 |
0.406 |
|
| 2015 |
Whitfield JH, Zhang WH, Herde MK, Clifton BE, Radziejewski J, Janovjak H, Henneberger C, Jackson CJ. Construction of a robust and sensitive arginine biosensor through ancestral protein reconstruction. Protein Science : a Publication of the Protein Society. 24: 1412-22. PMID 26061224 DOI: 10.1002/Pro.2721 |
0.334 |
|
| 2015 |
Sugrue E, Fraser NJ, Hopkins DH, Carr PD, Khurana JL, Oakeshott JG, Scott C, Jackson CJ. Evolutionary expansion of the amidohydrolase superfamily in bacteria in response to the synthetic compounds molinate and diuron. Applied and Environmental Microbiology. 81: 2612-24. PMID 25636851 DOI: 10.1128/Aem.04016-14 |
0.41 |
|
| 2014 |
Tokuriki N, Jackson CJ. Enzyme dynamics and engineering: one step at a time. Chemistry & Biology. 21: 1259-60. PMID 25373342 DOI: 10.1016/J.Chembiol.2014.10.003 |
0.366 |
|
| 2014 |
Jackson CJ, Coppin CW, Carr PD, Aleksandrov A, Wilding M, Sugrue E, Ubels J, Paks M, Newman J, Peat TS, Russell RJ, Field M, Weik M, Oakeshott JG, Scott C. 300-Fold increase in production of the Zn2+-dependent dechlorinase TrzN in soluble form via apoenzyme stabilization. Applied and Environmental Microbiology. 80: 4003-11. PMID 24771025 DOI: 10.1128/Aem.00916-14 |
0.395 |
|
| 2014 |
Naqvi T, Warden AC, French N, Sugrue E, Carr PD, Jackson CJ, Scott C. A 5000-fold increase in the specificity of a bacterial phosphotriesterase for malathion through combinatorial active site mutagenesis. Plos One. 9: e94177. PMID 24721933 DOI: 10.1371/Journal.Pone.0094177 |
0.43 |
|
| 2013 |
Zhang WH, Otting G, Jackson CJ. Protein engineering with unnatural amino acids. Current Opinion in Structural Biology. 23: 581-7. PMID 23835227 DOI: 10.1016/J.Sbi.2013.06.009 |
0.339 |
|
| 2013 |
Jackson CJ, Liu JW, Carr PD, Younus F, Coppin C, Meirelles T, Lethier M, Pandey G, Ollis DL, Russell RJ, Weik M, Oakeshott JG. Structure and function of an insect α-carboxylesterase (αEsterase7) associated with insecticide resistance. Proceedings of the National Academy of Sciences of the United States of America. 110: 10177-82. PMID 23733941 DOI: 10.1073/Pnas.1304097110 |
0.345 |
|
| 2012 |
Tokuriki N, Jackson CJ, Afriat-Jurnou L, Wyganowski KT, Tang R, Tawfik DS. Diminishing returns and tradeoffs constrain the laboratory optimization of an enzyme. Nature Communications. 3: 1257. PMID 23212386 DOI: 10.1038/Ncomms2246 |
0.399 |
|
| 2012 |
Afriat-Jurnou L, Jackson CJ, Tawfik DS. Reconstructing a missing link in the evolution of a recently diverged phosphotriesterase by active-site loop remodeling. Biochemistry. 51: 6047-55. PMID 22809311 DOI: 10.1021/Bi300694T |
0.393 |
|
| 2012 |
Noor S, Taylor MC, Russell RJ, Jermiin LS, Jackson CJ, Oakeshott JG, Scott C. Intramolecular epistasis and the evolution of a new enzymatic function. Plos One. 7: e39822. PMID 22768133 DOI: 10.1371/Journal.Pone.0039822 |
0.386 |
|
| 2012 |
Coppin CW, Jackson CJ, Sutherland T, Hart PJ, Devonshire AL, Russell RJ, Oakeshott JG. Testing the evolvability of an insect carboxylesterase for the detoxification of synthetic pyrethroid insecticides. Insect Biochemistry and Molecular Biology. 42: 343-52. PMID 22300675 DOI: 10.1016/J.Ibmb.2012.01.004 |
0.362 |
|
| 2011 |
Russell RJ, Scott C, Jackson CJ, Pandey R, Pandey G, Taylor MC, Coppin CW, Liu JW, Oakeshott JG. The evolution of new enzyme function: lessons from xenobiotic metabolizing bacteria versus insecticide-resistant insects. Evolutionary Applications. 4: 225-48. PMID 25567970 DOI: 10.1111/J.1752-4571.2010.00175.X |
0.401 |
|
| 2011 |
Sharma P, Pandey R, Kumari K, Pandey G, Jackson CJ, Russell RJ, Oakeshott JG, Lal R. Kinetic and sequence-structure-function analysis of known LinA variants with different hexachlorocyclohexane isomers. Plos One. 6: e25128. PMID 21949868 DOI: 10.1371/Journal.Pone.0025128 |
0.395 |
|
| 2011 |
Fraser JS, Jackson CJ. Mining electron density for functionally relevant protein polysterism in crystal structures Cellular and Molecular Life Sciences. 68: 1829-1841. PMID 21190057 DOI: 10.1007/S00018-010-0611-4 |
0.347 |
|
| 2011 |
Ugwumba IN, Ozawa K, Xu ZQ, Ely F, Foo JL, Herlt AJ, Coppin C, Brown S, Taylor MC, Ollis DL, Mander LN, Schenk G, Dixon NE, Otting G, Oakeshott JG, ... Jackson CJ, et al. Improving a natural enzyme activity through incorporation of unnatural amino acids. Journal of the American Chemical Society. 133: 326-33. PMID 21162578 DOI: 10.1021/Ja106416G |
0.364 |
|
| 2010 |
Taylor MC, Jackson CJ, Tattersall DB, French N, Peat TS, Newman J, Briggs LJ, Lapalikar GV, Campbell PM, Scott C, Russell RJ, Oakeshott JG. Identification and characterization of two families of F420 H2-dependent reductases from Mycobacteria that catalyse aflatoxin degradation. Molecular Microbiology. 78: 561-75. PMID 20807200 DOI: 10.1111/J.1365-2958.2010.07356.X |
0.362 |
|
| 2010 |
Lal R, Pandey G, Sharma P, Kumari K, Malhotra S, Pandey R, Raina V, Kohler HP, Holliger C, Jackson C, Oakeshott JG. Biochemistry of microbial degradation of hexachlorocyclohexane and prospects for bioremediation. Microbiology and Molecular Biology Reviews : Mmbr. 74: 58-80. PMID 20197499 DOI: 10.1128/Mmbr.00029-09 |
0.334 |
|
| 2010 |
Khersonsky O, Röthlisberger D, Dym O, Albeck S, Jackson CJ, Baker D, Tawfik DS. Evolutionary optimization of computationally designed enzymes: Kemp eliminases of the KE07 series. Journal of Molecular Biology. 396: 1025-42. PMID 20036254 DOI: 10.1016/J.Jmb.2009.12.031 |
0.402 |
|
| 2009 |
Jackson CJ, Foo JL, Tokuriki N, Afriat L, Carr PD, Kim HK, Schenk G, Tawfik DS, Ollis DL. Conformational sampling, catalysis, and evolution of the bacterial phosphotriesterase. Proceedings of the National Academy of Sciences of the United States of America. 106: 21631-6. PMID 19966226 DOI: 10.1073/Pnas.0907548106 |
0.413 |
|
| 2009 |
Weston DP, Jackson CJ. Use of engineered enzymes to identify organophosphate and pyrethroid-related toxicity in toxicity identification evaluations. Environmental Science & Technology. 43: 5514-20. PMID 19708390 DOI: 10.1021/Es900434Z |
0.348 |
|
| 2009 |
Jackson CJ, Weir K, Herlt A, Khurana J, Sutherland TD, Horne I, Easton C, Russell RJ, Scott C, Oakeshott JG. Structure-based rational design of a phosphotriesterase. Applied and Environmental Microbiology. 75: 5153-6. PMID 19502439 DOI: 10.1128/Aem.00629-09 |
0.349 |
|
| 2009 |
Scott C, Jackson CJ, Coppin CW, Mourant RG, Hilton ME, Sutherland TD, Russell RJ, Oakeshott JG. Catalytic improvement and evolution of atrazine chlorohydrolase. Applied and Environmental Microbiology. 75: 2184-91. PMID 19201959 DOI: 10.1128/Aem.02634-08 |
0.402 |
|
| 2009 |
Khurana JL, Jackson CJ, Scott C, Pandey G, Horne I, Russell RJ, Herlt A, Easton CJ, Oakeshott JG. Characterization of the phenylurea hydrolases A and B: founding members of a novel amidohydrolase subgroup. The Biochemical Journal. 418: 431-41. PMID 19000034 DOI: 10.1042/Bj20081488 |
0.405 |
|
| 2008 |
Scott C, Pandey G, Hartley CJ, Jackson CJ, Cheesman MJ, Taylor MC, Pandey R, Khurana JL, Teese M, Coppin CW, Weir KM, Jain RK, Lal R, Russell RJ, Oakeshott JG. The enzymatic basis for pesticide bioremediation. Indian Journal of Microbiology. 48: 65-79. PMID 23100701 DOI: 10.1007/S12088-008-0007-4 |
0.397 |
|
| 2008 |
Hadler KS, Tanifum EA, Yip SH, Mitić N, Guddat LW, Jackson CJ, Gahan LR, Nguyen K, Carr PD, Ollis DL, Hengge AC, Larrabee JA, Schenk G. Substrate-promoted formation of a catalytically competent binuclear center and regulation of reactivity in a glycerophosphodiesterase from Enterobacter aerogenes. Journal of the American Chemical Society. 130: 14129-38. PMID 18831553 DOI: 10.1021/Ja803346W |
0.382 |
|
| 2008 |
Jackson CJ, Taylor MC, Tattersall DB, French NG, Carr PD, Ollis DL, Russell RJ, Oakeshott JG. Cloning, expression, purification, crystallization and preliminary X-ray studies of a pyridoxine 5'-phosphate oxidase from Mycobacterium smegmatis. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 64: 435-7. PMID 18453720 DOI: 10.1107/S1744309108011512 |
0.308 |
|
| 2008 |
Jackson CJ, Foo JL, Kim HK, Carr PD, Liu JW, Salem G, Ollis DL. In crystallo capture of a Michaelis complex and product-binding modes of a bacterial phosphotriesterase. Journal of Molecular Biology. 375: 1189-96. PMID 18082180 DOI: 10.1016/J.Jmb.2007.10.061 |
0.324 |
|
| 2007 |
Jackson CJ, Carr PD, Liu JW, Watt SJ, Beck JL, Ollis DL. The structure and function of a novel glycerophosphodiesterase from Enterobacter aerogenes. Journal of Molecular Biology. 367: 1047-62. PMID 17306828 DOI: 10.1016/J.Jmb.2007.01.032 |
0.351 |
|
| 2006 |
Jackson CJ, Carr PD, Kim HK, Liu JW, Ollis DL. The purification, crystallization and preliminary diffraction of a glycerophosphodiesterase from Enterobacter aerogenes. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 62: 659-61. PMID 16820687 DOI: 10.1107/S1744309106020021 |
0.329 |
|
| 2006 |
Jackson CJ, Carr PD, Kim HK, Liu JW, Herrald P, Mitić N, Schenk G, Smith CA, Ollis DL. Anomalous scattering analysis of Agrobacterium radiobacter phosphotriesterase: the prominent role of iron in the heterobinuclear active site. The Biochemical Journal. 397: 501-8. PMID 16686603 DOI: 10.1042/Bj20060276 |
0.314 |
|
| 2005 |
Jackson CJ, Liu JW, Coote ML, Ollis DL. The effects of substrate orientation on the mechanism of a phosphotriesterase. Organic & Biomolecular Chemistry. 3: 4343-50. PMID 16327895 DOI: 10.1039/B512399B |
0.371 |
|
| 2005 |
Jackson C, Kim H, Carr PD, Liu J, Ollis DL. The structure of an enzyme-product complex reveals the critical role of a terminal hydroxide nucleophile in the bacterial phosphotriesterase mechanism Biochimica Et Biophysica Acta. 1752: 56-64. PMID 16054447 DOI: 10.1016/J.Bbapap.2005.06.008 |
0.417 |
|
| 2005 |
McLoughlin SY, Jackson C, Liu J, Ollis D. Increased expression of a bacterial phosphotriesterase in Escherichia coli through directed evolution Protein Expression and Purification. 41: 433-440. PMID 15866732 DOI: 10.1016/J.Pep.2005.01.012 |
0.334 |
|
| 2004 |
McLoughlin SY, Jackson C, Liu J, Ollis DL. Growth of Escherichia coli coexpressing phosphotriesterase and glycerophosphodiester phosphodiesterase, using paraoxon as the sole phosphorus source. Applied and Environmental Microbiology. 70: 404-412. PMID 14711669 DOI: 10.1128/Aem.70.1.404-412.2004 |
0.316 |
|
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