Abhishek Sharma - Publications

Affiliations: 
Stevens Institute of Technology 
Area:
Organic Chemistry, Medicinal Chemistry, Chemical Biology
Website:
https://www.sharmalab.org/

38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Vyas H, Gangani AJ, Mini A, Lin S, Chu JM, Agee CO, Gabriel J, Williamson RT, Zhang Y, Sharma A. Generation and Application of Homoallylic α,α-Diboryl Radicals via Diboron-Promoted Ring-Opening of Vinyl Cyclopropanes: cis-Diastereoselective Borylative Cycloaddition. Chemistry (Weinheim An Der Bergstrasse, Germany). e202303175. PMID 37793067 DOI: 10.1002/chem.202303175  0.8
2022 Wang L, Sharma A. SERDs: a case study in targeted protein degradation. Chemical Society Reviews. PMID 36073297 DOI: 10.1039/d2cs00117a  0.771
2022 Wang L, Lin S, Santos E, Pralat J, Spotton K, Sharma A. Boron-Promoted Deprotonative Conjugate Addition: Geminal Diborons as Soft Pronucleophiles and Acyl Anion Equivalents. The Journal of Organic Chemistry. PMID 35819798 DOI: 10.1021/acs.joc.2c00914  0.719
2021 Lin S, Wang L, Sharma A. Acrylic boronate: a multifunctional C3 building block for catalytic synthesis of rare organoborons and chemoselective heterobifunctional ligations. Chemical Science. 12: 7924-7929. PMID 34168846 DOI: 10.1039/d1sc00905b  0.82
2021 Wang L, Lin S, Zhu Y, Ferrante D, Ishak T, Baba Y, Sharma A. α-Hydroxy boron-enabled regioselective access to bifunctional halo-boryl alicyclic ethers and α-halo borons. Chemical Communications (Cambridge, England). 57: 4564-4567. PMID 33955990 DOI: 10.1039/d1cc00336d  0.822
2020 Sharma A, Wang L. The Quest for Orally Bioavailable Selective Estrogen Receptor Degraders (SERDs). Chemmedchem. PMID 32916035 DOI: 10.1002/Cmdc.202000473  0.791
2019 Lin S, Wang L, Aminoleslami N, Lao Y, Yagel C, Sharma A. A modular and concise approach to MIDA acylboronates chemoselective oxidation of unsymmetrical geminal diborylalkanes: unlocking access to a novel class of acylborons. Chemical Science. 10: 4684-4691. PMID 31123579 DOI: 10.1039/C9Sc00378A  0.681
2018 Sharma A, Toy W, Guillen VS, Sharma N, Min J, Carlson KE, Mayne CG, Lin S, Sabio M, Greene G, Katzenellenbogen BS, Chandarlapaty S, Katzenellenbogen JA. Antagonists for Constitutively Active Mutant Estrogen Receptors: Insights into the Roles of Antiestrogen-Core and Side-Chain. Acs Chemical Biology. PMID 30404440 DOI: 10.1021/Acschembio.8B00877  0.759
2018 Wang L, Guillen VS, Sharma N, Flessa K, Min J, Carlson KE, Toy W, Braqi S, Katzenellenbogen BS, Katzenellenbogen JA, Chandarlapaty S, Sharma A. New Class of Selective Estrogen Receptor Degraders (SERDs): Expanding the Toolbox of PROTAC Degrons. Acs Medicinal Chemistry Letters. 9: 803-808. PMID 30128071 DOI: 10.1021/Acsmedchemlett.8B00106  0.711
2018 Lin S, Sharma A. Recent advances in the synthesis and synthetic applications of 1,2,3-triazoles (microreview) Chemistry of Heterocyclic Compounds. 54: 314-316. DOI: 10.1007/S10593-018-2265-3  0.436
2017 Katzenellenbogen BS, Zhao Y, Laws MJ, Sanabria Guillen V, Ziegler Y, Min J, Sharma A, Kim SH, Chu D, Park BH, Oesterreich S, Mao C, Shapiro DJ, Nettles KW, Katzenellenbogen JA. Structurally novel antiestrogens elicit differential responses from constitutively active mutant estrogen receptors in breast cancer cells and tumors. Cancer Research. PMID 28904064 DOI: 10.1158/0008-5472.Can-17-1265  0.466
2017 Min J, Guillen VS, Sharma A, Zhao Y, Ziegler Y, Gong P, Mayne CG, Srinivasan S, Kim SH, Carlson KE, Nettles KW, Katzenellenbogen BS, Katzenellenbogen JA. Adamantyl Antiestrogens with Novel Side Chains Reveal a Spectrum of Activities in Suppressing Estrogen Receptor (ER)-Mediated Activities in Breast Cancer Cells. Journal of Medicinal Chemistry. PMID 28657320 DOI: 10.1021/Acs.Jmedchem.7B00585  0.721
2016 Sharma N, Carlson KE, Nwachukwu JC, Srinivasan S, Sharma A, Nettles KW, Katzenellenbogen JA. Exploring the Structural Compliancy versus Specificity of the Estrogen Receptor Using Isomeric Three-Dimensional Ligands. Acs Chemical Biology. PMID 28032978 DOI: 10.1021/Acschembio.6B00918  0.479
2016 Sharma N, Mohanakrishnan D, Shard A, Sharma A, Sinha AK, Sahal D. Hydroxylated di- and tri-styrylbenzenes, a new class of antiplasmodial agents: discovery and mechanism of action Rsc Advances. 6: 49348-49357. DOI: 10.1039/C6Ra06059E  0.633
2015 Hao Y, Blair PM, Sharma A, Mitchell DA, Nair SK. Insights into methyltransferase specificity and bioactivity of derivatives of the antibiotic plantazolicin. Acs Chemical Biology. 10: 1209-16. PMID 25635336 DOI: 10.1021/Cb501042A  0.522
2015 Fanning SW, Mayne C, Toy W, Shen Y, Sharma A, Panchamukhi S, Nowak J, Nettles KW, Chandarlapaty S, Katzenellenbogen JA, Greene GL. Abstract P3-05-07: Determining the role of somatic ERα mutations in acquired hormone (or SERM) resistance Cancer Research. 75. DOI: 10.1158/1538-7445.Sabcs14-P3-05-07  0.702
2014 Liao ZQ, Dong C, Carlson KE, Srinivasan S, Nwachukwu JC, Chesnut RW, Sharma A, Nettles KW, Katzenellenbogen JA, Zhou HB. Triaryl-substituted Schiff bases are high-affinity subtype-selective ligands for the estrogen receptor. Journal of Medicinal Chemistry. 57: 3532-45. PMID 24708493 DOI: 10.1021/Jm500268J  0.496
2013 Sharma A, Blair PM, Mitchell DA. Synthesis of plantazolicin analogues enables dissection of ligand binding interactions of a highly selective methyltransferase. Organic Letters. 15: 5076-9. PMID 24063702 DOI: 10.1021/Ol402444A  0.545
2013 Vachhani DD, Sharma A, Van der Eycken E. Copper-catalyzed direct secondary and tertiary C-H alkylation of azoles through a heteroarene-amine-aldehyde/ketone coupling reaction. Angewandte Chemie (International Ed. in English). 52: 2547-50. PMID 23341157 DOI: 10.1002/Anie.201209312  0.796
2013 Sharma A, Vacchani D, Van der Eycken E. Developments in direct C-H arylation of (hetero)arenes under microwave irradiation. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 1158-68. PMID 23293098 DOI: 10.1002/Chem.201201868  0.696
2013 Vachhani D, Modha S, Sharma A, Eycken EVd. A facile diversity-oriented synthesis of imidazo[1,2-a]pyrazinones via gold-catalyzed regioselective heteroannulation of propynylaminopyrazinones Tetrahedron. 69: 359-365. DOI: 10.1016/J.Tet.2012.10.019  0.801
2012 Vachhani DD, Sharma A, Van der Eycken E. Pd/Cu-catalyzed C-H arylation of 1,3,4-thiadiazoles with (hetero)aryl iodides, bromides, and triflates. The Journal of Organic Chemistry. 77: 8768-74. PMID 22957511 DOI: 10.1021/Jo301401Q  0.778
2012 Sharma A, Vachhani D, Van der Eycken E. Direct heteroarylation of tautomerizable heterocycles into unsymmetrical and symmetrical biheterocycles via Pd/Cu-catalyzed phosphonium coupling. Organic Letters. 14: 1854-7. PMID 22416815 DOI: 10.1021/Ol300455E  0.771
2012 Sharma N, Mohanakrishnan D, Shard A, Sharma A, Saima, Sinha AK, Sahal D. Stilbene-chalcone hybrids: design, synthesis, and evaluation as a new class of antimalarial scaffolds that trigger cell death through stage specific apoptosis. Journal of Medicinal Chemistry. 55: 297-311. PMID 22098429 DOI: 10.1021/Jm201216Y  0.759
2012 Sharma A, Appukkuttan P, Van der Eycken E. Microwave-assisted synthesis of medium-sized heterocycles. Chemical Communications (Cambridge, England). 48: 1623-37. PMID 22031184 DOI: 10.1039/C1Cc15238F  0.731
2011 Sharma N, Sharma A, Shard A, Kumar R, Saima, Sinha AK. Pd-catalyzed orthogonal Knoevenagel/Perkin condensation-decarboxylation-Heck/Suzuki sequences: tandem transformations of benzaldehydes into hydroxy-functionalized antidiabetic stilbene-cinnamoyl hybrids and asymmetric distyrylbenzenes. Chemistry (Weinheim An Der Bergstrasse, Germany). 17: 10350-6. PMID 21812043 DOI: 10.1002/Chem.201101174  0.806
2011 Sharma A, Sharma N, Shard A, Kumar R, Mohanakrishnan D, Saima, Sinha AK, Sahal D. Tandem allylic oxidation-condensation/esterification catalyzed by silica gel: an expeditious approach towards antimalarial diaryldienones and enones from natural methoxylated phenylpropenes. Organic & Biomolecular Chemistry. 9: 5211-9. PMID 21625717 DOI: 10.1039/C1Ob05293D  0.795
2011 Kumar R, Sharma N, Sharma N, Sharma A, Sinha AK. Metal-free activation of H₂O₂ by synergic effect of ionic liquid and microwave: chemoselective oxidation of benzylic alcohols to carbonyls and unexpected formation of anthraquinone in aqueous condition. Molecular Diversity. 15: 687-95. PMID 21113797 DOI: 10.1007/S11030-010-9292-Z  0.637
2010 Kumar R, Mohanakrishnan D, Sharma A, Kaushik NK, Kalia K, Sinha AK, Sahal D. Reinvestigation of structure-activity relationship of methoxylated chalcones as antimalarials: synthesis and evaluation of 2,4,5-trimethoxy substituted patterns as lead candidates derived from abundantly available natural β-asarone. European Journal of Medicinal Chemistry. 45: 5292-301. PMID 20863599 DOI: 10.1016/J.Ejmech.2010.08.049  0.617
2010 Sharma A, Sharma N, Kumar R, Shard A, Sinha AK. Direct olefination of benzaldehydes into hydroxy functionalized oligo (p-phenylenevinylene)s via Pd-catalyzed heterodomino Knoevenagel-decarboxylation-Heck sequence and its application for fluoride sensing pi-conjugated units. Chemical Communications (Cambridge, England). 46: 3283-5. PMID 20442887 DOI: 10.1039/C001980A  0.783
2010 Sharma N, Sharma A, Kumar R, Shard A, Sinha AK. One‐Pot Two‐Step Oxidative Cleavage of 1,2‐Arylalkenes to Aryl Ketones Instead of Arylaldehydes in an Aqueous Medium: A Complementary Approach to Ozonolysis European Journal of Organic Chemistry. 2010: 6025-6032. DOI: 10.1002/Ejoc.201000672  0.422
2009 Sharma A, Sharma N, Kumar R, Sharma UK, Sinha AK. Water-promoted cascade synthesis of alpha-arylaldehydes from arylalkenes using N-halosuccinimides: an avenue for asymmetric oxidation using Cinchona organocatalysis. Chemical Communications (Cambridge, England). 5299-301. PMID 19707652 DOI: 10.1039/B908717F  0.587
2008 Sharma UK, Sharma K, Sharma N, Sharma A, Singh HP, Sinha AK. Microwave-assisted efficient extraction of different parts of Hippophae rhamnoides for the comparative evaluation of antioxidant activity and quantification of its phenolic constituents by reverse-phase high-performance liquid chromatography (RP-HPLC). Journal of Agricultural and Food Chemistry. 56: 374-9. PMID 18163559 DOI: 10.1021/Jf072510J  0.547
2008 Kumar R, Sharma A, Sharma N, Kumar V, Sinha AK. Neutral Ionic Liquid [hmim]Br as a Green Reagent and Solvent for the Mild and Efficient Dehydration of Benzyl Alcohols into (E)‐Arylalkenes Under Microwave Irradiation European Journal of Organic Chemistry. 2008: 5577-5582. DOI: 10.1002/Ejoc.200800657  0.579
2008 Sharma A, Kumar R, Sharma N, Kumar V, Sinha AK. Unique Versatility of Ionic Liquids as Clean Decarboxylation Catalyst Cum Solvent: A Metal‐ and Quinoline‐Free Paradigm towards Synthesis of Indoles, Styrenes, Stilbenes and Arene Derivatives under Microwave Irradiation in Aqueous Conditions Advanced Synthesis & Catalysis. 350: 2910-2920. DOI: 10.1002/Adsc.200800537  0.627
2007 Sinha AK, Kumar V, Sharma A, Sharma A, Kumar R. An unusual, mild and convenient one-pot two-step access to (E)-stilbenes from hydroxy-substituted benzaldehydes and phenylacetic acids under microwave activation: a new facet of the classical Perkin reaction Tetrahedron. 63: 11070-11077. DOI: 10.1016/J.Tet.2007.08.034  0.454
2007 Kumar V, Sharma A, Sharma M, Sharma UK, Sinha AK. DDQ catalyzed benzylic acetoxylation of arylalkanes: a case of exquisitely controlled oxidation under sonochemical activation ☆ Tetrahedron. 63: 9718-9723. DOI: 10.1016/J.Tet.2007.07.018  0.629
2007 Kumar V, Sharma A, Sharma A, Sinha AK. Remarkable synergism in methylimidazole-promoted decarboxylation of substituted cinnamic acid derivatives in basic water medium under microwave irradiation: a clean synthesis of hydroxylated (E)-stilbenes Tetrahedron. 63: 7640-7646. DOI: 10.1016/J.Tet.2007.05.046  0.641
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