Mehdi Mollapour - Publications

Affiliations: 
University College London, London, United Kingdom 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Buchner J, Alasady MJ, Backe SJ, Blagg BS, Carpenter RL, Colombo G, Gelis I, Gewirth DT, Gierasch LM, Houry WA, Johnson JL, Kang BH, Kao AW, LaPointe P, Mattoo S, ... ... Mollapour M, et al. 2 International Symposium on the Chaperone Code, 2023. Cell Stress & Chaperones. PMID 38316354 DOI: 10.1016/j.cstres.2024.01.003  0.552
2024 Bourboulia D, Blair LJ, Clark MS, Edkins AL, Hightower LE, Mollapour M, Prahlad V, Repasky EA, Truebano M, Truman AW, Truttmann MC, van Oosten-Hawle P, Woodford MR. Editorial: A new chapter for Cell Stress and Chaperones. Cell Stress & Chaperones. PMID 38309687 DOI: 10.1016/j.cstres.2024.01.007  0.591
2024 Backe SJ, Sager RA, Heritz JA, Wengert LA, Meluni KA, Aran-Guiu X, Panaretou B, Woodford MR, Prodromou C, Bourboulia D, Mollapour M. Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery. Cell Reports. 43: 113672. PMID 38180838 DOI: 10.1016/j.celrep.2023.113672  0.36
2023 Sager RA, Backe SJ, Neckers L, Woodford MR, Mollapour M. Detecting Posttranslational Modifications of Hsp90 Isoforms. Methods in Molecular Biology (Clifton, N.J.). 2693: 125-139. PMID 37540432 DOI: 10.1007/978-1-0716-3342-7_11  0.41
2023 Backe SJ, Sager RA, Heritz JA, Wengert LA, Meluni KA, Aran-Guiu X, Panaretou B, Woodford MR, Prodromou C, Bourboulia D, Mollapour M. Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery. Cell Reports. 42: 112807. PMID 37453059 DOI: 10.1016/j.celrep.2023.112807  0.418
2023 Backe SJ, Mollapour M, Woodford MR. Saccharomyces cerevisiae as a tool for deciphering Hsp90 molecular chaperone function. Essays in Biochemistry. PMID 36912239 DOI: 10.1042/EBC20220224  0.323
2023 van Oosten-Hawle P, Backe SJ, Ben-Zvi A, Bourboulia D, Brancaccio M, Brodsky J, Clark M, Colombo G, Cox MB, De Los Rios P, Echtenkamp F, Edkins A, Freeman B, Goloubinoff P, Houry W, ... ... Mollapour M, et al. Second Virtual International Symposium on Cellular and Organismal Stress Responses, September 8-9, 2022. Cell Stress & Chaperones. PMID 36602710 DOI: 10.1007/s12192-022-01318-5  0.585
2022 Backe SJ, Woodford MR, Ahanin E, Sager RA, Bourboulia D, Mollapour M. Impact of Co-chaperones and Posttranslational Modifications Toward Hsp90 Drug Sensitivity. Sub-Cellular Biochemistry. 101: 319-350. PMID 36520312 DOI: 10.1007/978-3-031-14740-1_11  0.394
2022 Sager RA, Khan F, Toneatto L, Votra SD, Backe SJ, Woodford MR, Mollapour M, Bourboulia D. Targeting extracellular Hsp90: A unique frontier against cancer. Frontiers in Molecular Biosciences. 9: 982593. PMID 36060252 DOI: 10.3389/fmolb.2022.982593  0.346
2022 Backe SJ, Sager RA, Meluni KA, Woodford MR, Bourboulia D, Mollapour M. Emerging Link between Tsc1 and FNIP Co-Chaperones of Hsp90 and Cancer. Biomolecules. 12. PMID 35883484 DOI: 10.3390/biom12070928  0.405
2022 Backe SJ, Sager RA, Regan BR, Sit J, Major LA, Bratslavsky G, Woodford MR, Bourboulia D, Mollapour M. A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand. Cell Reports. 40: 111039. PMID 35830801 DOI: 10.1016/j.celrep.2022.111039  0.321
2021 Woodford MR, Backe SJ, Wengert LA, Dunn DM, Bourboulia D, Mollapour M. Hsp90 chaperone code and the tumor suppressor VHL cooperatively regulate the mitotic checkpoint. Cell Stress & Chaperones. 26: 965-971. PMID 34586601 DOI: 10.1007/s12192-021-01240-2  0.388
2021 Truman AW, Bourboulia D, Mollapour M. Decrypting the chaperone code. The Journal of Biological Chemistry. 296: 100293. PMID 33837727 DOI: 10.1016/j.jbc.2021.100293  0.522
2021 van Oosten-Hawle P, Bergink S, Blagg B, Brodsky J, Edkins A, Freeman B, Genest O, Hendershot L, Kampinga H, Johnson J, De Maio A, Masison D, Morano K, Multhoff G, Prodromou C, ... ... Mollapour M, et al. First Virtual International Congress on Cellular and Organismal Stress Responses, November 5-6, 2020. Cell Stress & Chaperones. PMID 33559835 DOI: 10.1007/s12192-021-01192-7  0.59
2020 Backe SJ, Sager RA, Woodford MR, Makedon AM, Mollapour M. Post-translational modifications of Hsp90 and translating the chaperone code. The Journal of Biological Chemistry. PMID 32527727 DOI: 10.1074/jbc.REV120.011833  0.398
2020 Colombo G, Paladino A, Woodford MR, Backe SJ, Sager RA, Kancherla P, Daneshvar MA, Chen VZ, Ahanin EF, Bourboulia D, Prodromou C, Bergamaschi G, Strada A, Cretich M, Gori A, ... ... Mollapour M, et al. Chemical Perturbation of Oncogenic Protein Folding: from the Prediction of Locally Unstable Structures to the Design of Disruptors of Hsp90-Client Interactions. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32167602 DOI: 10.1002/Chem.202000615  0.342
2020 D'Annessa I, Hurwitz N, Pirota V, Beretta GL, Tinelli S, Woodford M, Freccero M, Mollapour M, Zaffaroni N, Wolfson H, Colombo G. Design of Disruptors of the Hsp90-Cdc37 Interface. Molecules (Basel, Switzerland). 25. PMID 31952296 DOI: 10.3390/molecules25020360  0.347
2019 Woodford MR, Hughes M, Sager RA, Backe SJ, Baker-Williams AJ, Bratslavsky MS, Jacob JM, Shapiro O, Wong M, Bratslavsky G, Bourboulia D, Mollapour M. Mutation of the co-chaperone Tsc1 in bladder cancer diminishes Hsp90 acetylation and reduces drug sensitivity and selectivity. Oncotarget. 10: 5824-5834. PMID 31645902 DOI: 10.18632/oncotarget.27217  0.329
2019 Sager RA, Woodford MR, Backe SJ, Makedon AM, Baker-Williams AJ, DiGregorio BT, Loiselle DR, Haystead TA, Zachara NE, Prodromou C, Bourboulia D, Schmidt LS, Linehan WM, Bratslavsky G, Mollapour M. Post-translational Regulation of FNIP1 Creates a Rheostat for the Molecular Chaperone Hsp90. Cell Reports. 26: 1344-1356.e5. PMID 30699359 DOI: 10.1016/J.Celrep.2019.01.018  0.398
2018 Cortes S, Baker-Williams AJ, Mollapour M, Bourboulia D. Detection and Analysis of Extracellular Hsp90 (eHsp90). Methods in Molecular Biology (Clifton, N.J.). 1709: 321-329. PMID 29177669 DOI: 10.1007/978-1-4939-7477-1_23  0.33
2018 Sager RA, Woodford MR, Neckers L, Mollapour M. Detecting Posttranslational Modifications of Hsp90. Methods in Molecular Biology (Clifton, N.J.). 1709: 209-219. PMID 29177662 DOI: 10.1007/978-1-4939-7477-1_16  0.411
2018 Dushukyan N, Daneshvar M, Sager R, Woodford M, Baker-Williams A, Chisholm J, Loiselle D, Truman A, Haystead T, Shapiro O, Bourboulia D, Bratslavsky G, Mollapour M. PD46-11 PHOSPHORYLATION AND UBIQUITINATION REGULATE PROTEIN PHOSPHATASE-5 ACTIVITY AND ITS PROSURVIVAL ROLE IN KIDNEY CANCER Journal of Urology. 199. DOI: 10.1016/J.Juro.2018.02.2159  0.579
2017 Dushukyan N, Dunn DM, Sager RA, Woodford MR, Loiselle DR, Daneshvar M, Baker-Williams AJ, Chisholm JD, Truman AW, Vaughan CK, Haystead TA, Bratslavsky G, Bourboulia D, Mollapour M. Phosphorylation and Ubiquitination Regulate Protein Phosphatase 5 Activity and Its Prosurvival Role in Kidney Cancer. Cell Reports. 21: 1883-1895. PMID 29141220 DOI: 10.1016/J.Celrep.2017.10.074  0.662
2017 Woodford MR, Sager RA, Marris E, Dunn DM, Blanden AR, Murphy RL, Rensing N, Shapiro O, Panaretou B, Prodromou C, Loh SN, Gutmann DH, Bourboulia D, Bratslavsky G, Wong M, ... Mollapour M, et al. Tumor suppressor Tsc1 is a new Hsp90 co-chaperone that facilitates folding of kinase and non-kinase clients. The Embo Journal. PMID 29127155 DOI: 10.15252/Embj.201796700  0.403
2016 Oberoi J, Dunn DM, Woodford MR, Mariotti L, Schulman J, Bourboulia D, Mollapour M, Vaughan CK. Structural and functional basis of protein phosphatase 5 substrate specificity. Proceedings of the National Academy of Sciences of the United States of America. PMID 27466404 DOI: 10.1073/pnas.1603059113  0.364
2016 Woodford MR, Dunn DM, Blanden AR, Capriotti D, Loiselle D, Prodromou C, Panaretou B, Hughes PF, Smith A, Ackerman W, Haystead TA, Loh SN, Bourboulia D, Schmidt LS, Marston Linehan W, ... ... Mollapour M, et al. The FNIP co-chaperones decelerate the Hsp90 chaperone cycle and enhance drug binding. Nature Communications. 7: 12037. PMID 27353360 DOI: 10.1038/Ncomms12037  0.392
2016 Woodford MR, Dunn DM, Ciciarelli JG, Beebe K, Neckers L, Mollapour M. Targeting Hsp90 in Non-Cancerous Maladies. Current Topics in Medicinal Chemistry. PMID 27072697  0.357
2016 Woodford MR, Dunn D, Miller JB, Jamal S, Neckers L, Mollapour M. Impact of Posttranslational Modifications on the Anticancer Activity of Hsp90 Inhibitors. Advances in Cancer Research. 129: 31-50. PMID 26916000 DOI: 10.1016/bs.acr.2015.09.002  0.405
2016 Woodford MR, Truman AW, Dunn DM, Jensen SM, Cotran R, Bullard R, Abouelleil M, Beebe K, Wolfgeher D, Wierzbicki S, Post DE, Caza T, Tsutsumi S, Panaretou B, Kron SJ, ... ... Mollapour M, et al. Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors. Cell Reports. 14: 872-84. PMID 26804907 DOI: 10.1016/J.Celrep.2015.12.084  0.686
2015 Wolfgeher D, Dunn DM, Woodford MR, Bourboulia D, Bratslavsky G, Mollapour M, Kron SJ, Truman AW. The dynamic interactome of human Aha1 upon Y223 phosphorylation. Data in Brief. 5: 752-5. PMID 26693507 DOI: 10.1016/J.Dib.2015.10.028  0.665
2015 Dunn DM, Woodford MR, Truman AW, Jensen SM, Schulman J, Caza T, Remillard TC, Loiselle D, Wolfgeher D, Blagg BS, Franco L, Haystead TA, Daturpalli S, Mayer MP, Trepel JB, ... ... Mollapour M, et al. c-Abl Mediated Tyrosine Phosphorylation of Aha1 Activates Its Co-chaperone Function in Cancer Cells. Cell Reports. 12: 1006-18. PMID 26235616 DOI: 10.1016/J.Celrep.2015.07.004  0.695
2015 Abouelleil M, Dunn D, Woodford M, Jensen S, Chehab M, Madala A, Caza T, Landas S, Stetler-Stevenson WG, Neckers L, Bourboulia D, Bratslavsky G, Mollapour M. MP39-02 OVEREXPRESSION OF MPS1 IN CLEAR CELL RENAL CELL CARCINOMA (CCRCC) CONFERS TUMOR SELECTIVITY ON HEAT SHOCK PROTEIN-90 (HSP90) INHIBITORS Journal of Urology. 193. DOI: 10.1016/J.Juro.2015.02.752  0.5
2014 Mollapour M, Bourboulia D, Beebe K, Woodford MR, Polier S, Hoang A, Chelluri R, Li Y, Guo A, Lee MJ, Fotooh-Abadi E, Khan S, Prince T, Miyajima N, Yoshida S, et al. Asymmetric Hsp90 N domain SUMOylation recruits Aha1 and ATP-competitive inhibitors. Molecular Cell. 53: 317-29. PMID 24462205 DOI: 10.1016/J.Molcel.2013.12.007  0.492
2013 Miyajima N, Tsutsumi S, Sourbier C, Beebe K, Mollapour M, Rivas C, Yoshida S, Trepel JB, Huang Y, Tatokoro M, Shinohara N, Nonomura K, Neckers L. The HSP90 inhibitor ganetespib synergizes with the MET kinase inhibitor crizotinib in both crizotinib-sensitive and -resistant MET-driven tumor models. Cancer Research. 73: 7022-33. PMID 24121490 DOI: 10.1158/0008-5472.CAN-13-1156  0.317
2013 Beebe K, Mollapour M, Scroggins B, Prodromou C, Xu W, Tokita M, Taldone T, Pullen L, Zierer BK, Lee MJ, Trepel J, Buchner J, Bolon D, Chiosis G, Neckers L. Posttranslational modification and conformational state of heat shock protein 90 differentially affect binding of chemically diverse small molecule inhibitors. Oncotarget. 4: 1065-74. PMID 23867252 DOI: 10.18632/Oncotarget.1099  0.451
2013 Walton-Diaz A, Khan S, Bourboulia D, Trepel JB, Neckers L, Mollapour M. Contributions of co-chaperones and post-translational modifications towards Hsp90 drug sensitivity. Future Medicinal Chemistry. 5: 1059-71. PMID 23734688 DOI: 10.4155/Fmc.13.88  0.472
2013 Alarcon SV, Mollapour M, Lee MJ, Tsutsumi S, Lee S, Kim YS, Prince T, Apolo AB, Giaccone G, Xu W, Neckers LM, Trepel JB. Tumor-intrinsic and tumor-extrinsic factors impacting hsp90- targeted therapy. Current Molecular Medicine. 12: 1125-41. PMID 22804236 DOI: 10.2174/156652412803306729  0.452
2012 Iwai A, Bourboulia D, Mollapour M, Jensen-Taubman S, Lee S, Donnelly AC, Yoshida S, Miyajima N, Tsutsumi S, Smith AK, Sun D, Wu X, Blagg BS, Trepel JB, Stetler-Stevenson WG, et al. Combined inhibition of Wee1 and Hsp90 activates intrinsic apoptosis in cancer cells. Cell Cycle (Georgetown, Tex.). 11: 3649-55. PMID 22935698 DOI: 10.4161/Cc.21926  0.481
2012 Xu W, Mollapour M, Prodromou C, Wang S, Scroggins BT, Palchick Z, Beebe K, Siderius M, Lee MJ, Couvillon A, Trepel JB, Miyata Y, Matts R, Neckers L. Dynamic tyrosine phosphorylation modulates cycling of the HSP90-P50(CDC37)-AHA1 chaperone machine. Molecular Cell. 47: 434-43. PMID 22727666 DOI: 10.1016/J.Molcel.2012.05.015  0.462
2012 Tsutsumi S, Mollapour M, Prodromou C, Lee CT, Panaretou B, Yoshida S, Mayer MP, Neckers LM. Charged linker sequence modulates eukaryotic heat shock protein 90 (Hsp90) chaperone activity. Proceedings of the National Academy of Sciences of the United States of America. 109: 2937-42. PMID 22315411 DOI: 10.1073/Pnas.1114414109  0.429
2012 Mollapour M, Piper PW. Activity of the yeast zinc-finger transcription factor War1 is lost with alanine mutation of two putative phosphorylation sites in the activation domain. Yeast (Chichester, England). 29: 39-44. PMID 22113732 DOI: 10.1002/Yea.1915  0.644
2012 Mollapour M, Neckers L. Post-translational modifications of Hsp90 and their contributions to chaperone regulation. Biochimica Et Biophysica Acta. 1823: 648-55. PMID 21856339 DOI: 10.1016/J.Bbamcr.2011.07.018  0.485
2011 Mollapour M, Neckers L. Detecting HSP90 phosphorylation. Methods in Molecular Biology (Clifton, N.J.). 787: 67-74. PMID 21898227 DOI: 10.1007/978-1-61779-295-3_5  0.506
2011 Mollapour M, Tsutsumi S, Kim YS, Trepel J, Neckers L. Casein kinase 2 phosphorylation of Hsp90 threonine 22 modulates chaperone function and drug sensitivity. Oncotarget. 2: 407-17. PMID 21576760 DOI: 10.18632/Oncotarget.272  0.496
2011 Mollapour M, Tsutsumi S, Truman AW, Xu W, Vaughan CK, Beebe K, Konstantinova A, Vourganti S, Panaretou B, Piper PW, Trepel JB, Prodromou C, Pearl LH, Neckers L. Threonine 22 phosphorylation attenuates Hsp90 interaction with cochaperones and affects its chaperone activity. Molecular Cell. 41: 672-81. PMID 21419342 DOI: 10.1016/J.Molcel.2011.02.011  0.758
2011 Matts RL, Brandt GE, Lu Y, Dixit A, Mollapour M, Wang S, Donnelly AC, Neckers L, Verkhivker G, Blagg BS. A systematic protocol for the characterization of Hsp90 modulators. Bioorganic & Medicinal Chemistry. 19: 684-92. PMID 21129982 DOI: 10.1016/J.Bmc.2010.10.029  0.367
2010 Trepel J, Mollapour M, Giaccone G, Neckers L. Targeting the dynamic HSP90 complex in cancer. Nature Reviews. Cancer. 10: 537-49. PMID 20651736 DOI: 10.1038/Nrc2887  0.444
2010 Mollapour M, Tsutsumi S, Neckers L. Hsp90 phosphorylation, Wee1 and the cell cycle. Cell Cycle (Georgetown, Tex.). 9: 2310-6. PMID 20519952 DOI: 10.4161/Cc.9.12.12054  0.522
2010 Mollapour M, Tsutsumi S, Donnelly AC, Beebe K, Tokita MJ, Lee MJ, Lee S, Morra G, Bourboulia D, Scroggins BT, Colombo G, Blagg BS, Panaretou B, Stetler-Stevenson WG, Trepel JB, et al. Swe1Wee1-dependent tyrosine phosphorylation of Hsp90 regulates distinct facets of chaperone function. Molecular Cell. 37: 333-43. PMID 20159553 DOI: 10.1016/J.Molcel.2010.01.005  0.701
2009 Tsutsumi S, Mollapour M, Graf C, Lee CT, Scroggins BT, Xu W, Haslerova L, Hessling M, Konstantinova AA, Trepel JB, Panaretou B, Buchner J, Mayer MP, Prodromou C, Neckers L. Hsp90 charged-linker truncation reverses the functional consequences of weakened hydrophobic contacts in the N domain. Nature Structural & Molecular Biology. 16: 1141-7. PMID 19838189 DOI: 10.1038/Nsmb.1682  0.428
2009 Mollapour M, Shepherd A, Piper PW. Presence of the Fps1p aquaglyceroporin channel is essential for Hog1p activation, but suppresses Slt2(Mpk1)p activation, with acetic acid stress of yeast. Microbiology (Reading, England). 155: 3304-11. PMID 19608606 DOI: 10.1099/Mic.0.030502-0  0.642
2009 Millson SH, Nuttall JM, Mollapour M, Piper PW. The Hsp90/Cdc37p chaperone system is a determinant of molybdate resistance in Saccharomyces cerevisiae. Yeast (Chichester, England). 26: 339-47. PMID 19399909 DOI: 10.1002/Yea.1670  0.677
2009 Neckers L, Mollapour M, Tsutsumi S. The complex dance of the molecular chaperone Hsp90. Trends in Biochemical Sciences. 34: 223-6. PMID 19359180 DOI: 10.1016/J.Tibs.2009.01.006  0.384
2008 Vaughan CK, Mollapour M, Smith JR, Truman A, Hu B, Good VM, Panaretou B, Neckers L, Clarke PA, Workman P, Piper PW, Prodromou C, Pearl LH. Hsp90-dependent activation of protein kinases is regulated by chaperone-targeted dephosphorylation of Cdc37. Molecular Cell. 31: 886-95. PMID 18922470 DOI: 10.1016/J.Molcel.2008.07.021  0.745
2008 Mollapour M, Shepherd A, Piper PW. Novel stress responses facilitate Saccharomyces cerevisiae growth in the presence of the monocarboxylate preservatives. Yeast (Chichester, England). 25: 169-77. PMID 18240334 DOI: 10.1002/Yea.1576  0.635
2007 Millson SH, Truman AW, Rácz A, Hu B, Panaretou B, Nuttall J, Mollapour M, Söti C, Piper PW. Expressed as the sole Hsp90 of yeast, the α and β isoforms of human Hsp90 differ with regard to their capacities for activation of certain client proteins, whereas only Hsp90β generates sensitivity to the Hsp90 inhibitor radicicol Febs Journal. 274: 4453-4463. PMID 17681020 DOI: 10.1111/J.1742-4658.2007.05974.X  0.773
2007 Mollapour M, Piper PW. Hog1 mitogen-activated protein kinase phosphorylation targets the yeast Fps1 aquaglyceroporin for endocytosis, thereby rendering cells resistant to acetic acid. Molecular and Cellular Biology. 27: 6446-56. PMID 17620418 DOI: 10.1128/Mcb.02205-06  0.655
2007 Truman AW, Millson SH, Nuttall JM, Mollapour M, Prodromou C, Piper PW. In the yeast heat shock response, Hsf1-directed induction of Hsp90 facilitates the activation of the Slt2 (Mpk1) mitogen-activated protein kinase required for cell integrity Eukaryotic Cell. 6: 744-752. PMID 17293484 DOI: 10.1128/Ec.00009-07  0.756
2006 Mollapour M, Piper PW. Hog1p mitogen-activated protein kinase determines acetic acid resistance in Saccharomyces cerevisiae. Fems Yeast Research. 6: 1274-80. PMID 17156024 DOI: 10.1111/J.1567-1364.2006.00118.X  0.626
2006 Truman AW, Millson SH, Nuttall JM, King V, Mollapour M, Prodromou C, Pearl LH, Piper PW. Expressed in the yeast Saccharomyces cerevisiae, human ERK5 is a client of the Hsp90 chaperone that complements loss of the Slt2p (Mpk1p) cell integrity stress-activated protein kinase Eukaryotic Cell. 5: 1914-1924. PMID 16950928 DOI: 10.1128/Ec.00263-06  0.76
2006 Mollapour M, Phelan JP, Millson SH, Piper PW, Cooke FT. Weak acid and alkali stress regulate phosphatidylinositol bisphosphate synthesis in Saccharomyces cerevisiae. The Biochemical Journal. 395: 73-80. PMID 16316315 DOI: 10.1042/Bj20051765  0.606
2005 Hu B, Liao C, Millson SH, Mollapour M, Prodromou C, Pearl LH, Piper PW, Panaretou B. Qri2/Nse4, a component of the essential Smc5/6 DNA repair complex. Molecular Microbiology. 55: 1735-50. PMID 15752197 DOI: 10.1111/J.1365-2958.2005.04531.X  0.577
2005 Harris N, Bachler M, Costa V, Mollapour M, Moradas-Ferreira P, Piper PW. Overexpressed Sod1p acts either to reduce or to increase the lifespans and stress resistance of yeast, depending on whether it is Cu(2+)-deficient or an active Cu,Zn-superoxide dismutase. Aging Cell. 4: 41-52. PMID 15659212 DOI: 10.1111/J.1474-9726.2005.00142.X  0.559
2004 Mollapour M, Fong D, Balakrishnan K, Harris N, Thompson S, Schüller C, Kuchler K, Piper PW. Screening the yeast deletant mutant collection for hypersensitivity and hyper-resistance to sorbate, a weak organic acid food preservative. Yeast (Chichester, England). 21: 927-46. PMID 15334557 DOI: 10.1002/Yea.1141  0.614
2004 Schüller C, Mamnun YM, Mollapour M, Krapf G, Schuster M, Bauer BE, Piper PW, Kuchler K. Global phenotypic analysis and transcriptional profiling defines the weak acid stress response regulon in Saccharomyces cerevisiae. Molecular Biology of the Cell. 15: 706-20. PMID 14617816 DOI: 10.1091/Mbc.E03-05-0322  0.622
2003 Piper PW, Millson SH, Mollapour M, Panaretou B, Siligardi G, Pearl LH, Prodromou C. Sensitivity to Hsp90-targeting drugs can arise with mutation to the Hsp90 chaperone, cochaperones and plasma membrane ATP binding cassette transporters of yeast. European Journal of Biochemistry. 270: 4689-95. PMID 14622256 DOI: 10.1046/J.1432-1033.2003.03866.X  0.66
2003 Bauer BE, Rossington D, Mollapour M, Mamnun Y, Kuchler K, Piper PW. Weak organic acid stress inhibits aromatic amino acid uptake by yeast, causing a strong influence of amino acid auxotrophies on the phenotypes of membrane transporter mutants. European Journal of Biochemistry. 270: 3189-95. PMID 12869194 DOI: 10.1046/J.1432-1033.2003.03701.X  0.608
2003 Harris N, Costa V, MacLean M, Mollapour M, Moradas-Ferreira P, Piper PW. Mnsod overexpression extends the yeast chronological (G(0)) life span but acts independently of Sir2p histone deacetylase to shorten the replicative life span of dividing cells. Free Radical Biology & Medicine. 34: 1599-606. PMID 12788479 DOI: 10.1016/S0891-5849(03)00210-7  0.587
2003 Hatzixanthis K, Mollapour M, Seymour I, Bauer BE, Krapf G, Schüller C, Kuchler K, Piper PW. Moderately lipophilic carboxylate compounds are the selective inducers of the Saccharomyces cerevisiae Pdr12p ATP-binding cassette transporter. Yeast (Chichester, England). 20: 575-85. PMID 12734796 DOI: 10.1002/Yea.981  0.612
2003 Kren A, Mamnun YM, Bauer BE, Schüller C, Wolfger H, Hatzixanthis K, Mollapour M, Gregori C, Piper P, Kuchler K. War1p, a novel transcription factor controlling weak acid stress response in yeast. Molecular and Cellular Biology. 23: 1775-85. PMID 12588995 DOI: 10.1128/Mcb.23.5.1775-1785.2003  0.647
2003 Piper PW, Panaretou B, Millson SH, Truman A, Mollapour M, Pearl LH, Prodromou C. Yeast is selectively hypersensitised to heat shock protein 90 (Hsp90)-targetting drugs with heterologous expression of the human Hsp90beta, a property that can be exploited in screens for new Hsp90 chaperone inhibitors. Gene. 302: 165-70. PMID 12527207 DOI: 10.1016/S0378-1119(02)01102-2  0.75
2002 Piper PW, Jones GW, Bringloe D, Harris N, MacLean M, Mollapour M. The shortened replicative life span of prohibitin mutants of yeast appears to be due to defective mitochondrial segregation in old mother cells. Aging Cell. 1: 149-57. PMID 12882345 DOI: 10.1046/J.1474-9728.2002.00018.X  0.583
2002 Panaretou B, Siligardi G, Meyer P, Maloney A, Sullivan JK, Singh S, Millson SH, Clarke PA, Naaby-Hansen S, Stein R, Cramer R, Mollapour M, Workman P, Piper PW, Pearl LH, et al. Activation of the ATPase activity of hsp90 by the stress-regulated cochaperone aha1. Molecular Cell. 10: 1307-18. PMID 12504007 DOI: 10.1016/S1097-2765(02)00785-2  0.69
2002 Mollapour M, Piper PW. The ZbYME2 gene from the food spoilage yeast Zygosaccharomyces bailii confers not only YME2 functions in Saccharomyces cerevisiae, but also the capacity for catabolism of sorbate and benzoate, two major weak organic acid preservatives. Molecular Microbiology. 42: 919-30. PMID 11737636 DOI: 10.1046/J.1365-2958.2001.02686.X  0.613
2001 Piper P, Calderon CO, Hatzixanthis K, Mollapour M. Weak acid adaptation: the stress response that confers yeasts with resistance to organic acid food preservatives. Microbiology (Reading, England). 147: 2635-2642. PMID 11577142 DOI: 10.1099/00221287-147-10-2635  0.593
2001 Mollapour M, Piper P. Targeted gene deletion in Zygosaccharomyces bailii. Yeast (Chichester, England). 18: 173-86. PMID 11169759 DOI: 10.1002/1097-0061(20010130)18:2<173::Aid-Yea663>3.0.Co;2-F  0.577
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