Susan T. Sharfstein - Publications

Affiliations: 
Chemical and Biological Engineering and Center for Biotechnology and Interdisciplinary Science Rensselaer Polytechnic Institute, Troy, NY, United States 

37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Tejwani V, Andersen MR, Nam JH, Sharfstein ST. Glycoengineering in CHO cells: Advances in systems biology. Biotechnology Journal. PMID 29316325 DOI: 10.1002/biot.201700234  0.44
2017 Terracina JJ, Sharfstein ST, Bergkvist M. In silico characterization of enantioselective molecularly imprinted binding sites. Journal of Molecular Recognition : Jmr. PMID 28120352 DOI: 10.1002/jmr.2612  0.32
2016 Torrejon KY, Papke EL, Halman JR, Bergkvist M, Danias J, Sharfstein ST, Xie Y. TGFβ2-induced outflow alterations in a bioengineered trabecular meshwork are offset by a rho-associated kinase inhibitor. Scientific Reports. 6: 38319. PMID 27924833 DOI: 10.1038/srep38319  0.32
2016 Oduah EI, Linhardt RJ, Sharfstein ST. Heparin: Past, Present, and Future. Pharmaceuticals (Basel, Switzerland). 9. PMID 27384570 DOI: 10.3390/ph9030038  1
2016 Sharfstein ST. Omics insights into production-scale bioreactors Biotechnology Journal. 11: 1124-1125. PMID 27351837 DOI: 10.1002/biot.201600338  1
2016 Terracina JJ, Bergkvist M, Sharfstein ST. Computational investigation of stoichiometric effects, binding site heterogeneities, and selectivities of molecularly imprinted polymers. Journal of Molecular Modeling. 22: 139. PMID 27207254 DOI: 10.1007/s00894-016-3005-1  1
2015 Torrejon KY, Papke EL, Halman JR, Stolwijk J, Dautriche CN, Bergkvist M, Danias J, Sharfstein ST, Xie Y. Bioengineered glaucomatous 3D human trabecular meshwork as an in vitro disease model. Biotechnology and Bioengineering. PMID 26615056 DOI: 10.1002/bit.25899  1
2015 Dautriche CN, Tian Y, Xie Y, Sharfstein ST. A Closer Look at Schlemm's Canal Cell Physiology: Implications for Biomimetics. Journal of Functional Biomaterials. 6: 963-85. PMID 26402712 DOI: 10.3390/jfb6030963  0.32
2015 Dautriche CN, Szymanski D, Kerr M, Torrejon KY, Bergkvist M, Xie Y, Danias J, Stamer WD, Sharfstein ST. A biomimetic Schlemm's canal inner wall: A model to study outflow physiology, glaucoma pathology and high-throughput drug screening. Biomaterials. 65: 86-92. PMID 26142779 DOI: 10.1016/j.biomaterials.2015.06.034  1
2015 Baik JY, Dahodwala H, Oduah E, Talman L, Gemmill TR, Gasimli L, Datta P, Yang B, Li G, Zhang F, Li L, Linhardt RJ, Campbell AM, Gorfien SF, Sharfstein ST. Optimization of bioprocess conditions improves production of a CHO cell-derived, bioengineered heparin. Biotechnology Journal. 10: 1067-81. PMID 26037948 DOI: 10.1002/biot.201400665  1
2015 Datta P, Yang B, Linhardt RJ, Sharfstein ST. Modulation of heparan sulfate biosynthesis by sodium butyrate in recombinant CHO cells. Cytotechnology. 67: 223-35. PMID 24468831 DOI: 10.1007/s10616-013-9677-9  1
2014 Dautriche CN, Xie Y, Sharfstein ST. Walking through trabecular meshwork biology: Toward engineering design of outflow physiology. Biotechnology Advances. 32: 971-83. PMID 24806891 DOI: 10.1016/j.biotechadv.2014.04.012  1
2014 Gasimli L, Glass CA, Datta P, Yang B, Li G, Gemmill TR, Baik JY, Sharfstein ST, Esko JD, Linhardt RJ. Bioengineering murine mastocytoma cells to produce anticoagulant heparin. Glycobiology. 24: 272-80. PMID 24326668 DOI: 10.1093/glycob/cwt108  1
2014 Datta P, Meli L, Li L, Migliore N, Schaefer E, Sharfstein ST, Dordick JS, Linhardt RJ. Microarray platform affords improved product analysis in mammalian cell growth studies. Biotechnology Journal. 9: 386-95. PMID 24227746 DOI: 10.1002/biot.201300288  1
2013 Datta P, Li G, Yang B, Zhao X, Baik JY, Gemmill TR, Sharfstein ST, Linhardt RJ. Bioengineered Chinese hamster ovary cells with Golgi-targeted 3-O-sulfotransferase-1 biosynthesize heparan sulfate with an antithrombin-binding site. The Journal of Biological Chemistry. 288: 37308-18. PMID 24247246 DOI: 10.1074/jbc.M113.519033  1
2013 Torrejon KY, Pu D, Bergkvist M, Danias J, Sharfstein ST, Xie Y. Recreating a human trabecular meshwork outflow system on microfabricated porous structures. Biotechnology and Bioengineering. 110: 3205-18. PMID 23775275 DOI: 10.1002/bit.24977  1
2013 Datta P, Linhardt RJ, Sharfstein ST. An 'omics approach towards CHO cell engineering. Biotechnology and Bioengineering. 110: 1255-71. PMID 23322664 DOI: 10.1002/bit.24841  1
2012 Zhang H, Lee MY, Hogg MG, Dordick JS, Sharfstein ST. High-throughput transfection of interfering RNA into a 3D cell-culture chip. Small (Weinheim An Der Bergstrasse, Germany). 8: 2091-8. PMID 22511323 DOI: 10.1002/smll.201102205  1
2012 Mason M, Sweeney B, Cain K, Stephens P, Sharfstein ST. Identifying bottlenecks in transient and stable production of recombinant monoclonal-antibody sequence variants in Chinese hamster ovary cells. Biotechnology Progress. 28: 846-55. PMID 22467228 DOI: 10.1002/btpr.1542  1
2012 Baik JY, Gasimli L, Yang B, Datta P, Zhang F, Glass CA, Esko JD, Linhardt RJ, Sharfstein ST. Metabolic engineering of Chinese hamster ovary cells: towards a bioengineered heparin. Metabolic Engineering. 14: 81-90. PMID 22326251 DOI: 10.1016/j.ymben.2012.01.008  1
2012 Dahodwala H, Nowey M, Mitina T, Sharfstein ST. Effects of clonal variation on growth, metabolism, and productivity in response to trophic factor stimulation: a study of Chinese hamster ovary cells producing a recombinant monoclonal antibody. Cytotechnology. 64: 27-41. PMID 21822681 DOI: 10.1007/s10616-011-9388-z  1
2011 Kiehl TR, Shen D, Khattak SF, Jian Li Z, Sharfstein ST. Observations of cell size dynamics under osmotic stress. Cytometry. Part a : the Journal of the International Society For Analytical Cytology. 79: 560-9. PMID 21656664 DOI: 10.1002/cyto.a.21076  1
2011 Baughman AC, Sharfstein ST, Martin LL. A flexible state-space approach for the modeling of metabolic networks I: development of mathematical methods. Metabolic Engineering. 13: 125-37. PMID 21163361 DOI: 10.1016/j.ymben.2010.12.002  1
2011 Baughman AC, Sharfstein ST, Martin LL. A flexible state-space approach for the modeling of metabolic networks II: advanced interrogation of hybridoma metabolism. Metabolic Engineering. 13: 138-49. PMID 21163360 DOI: 10.1016/j.ymben.2010.12.003  1
2010 Zhang H, Lee MY, Hogg MG, Dordick JS, Sharfstein ST. Gene delivery in three-dimensional cell cultures by superparamagnetic nanoparticles. Acs Nano. 4: 4733-43. PMID 20731451 DOI: 10.1021/nn9018812  1
2010 Shen D, Kiehl TR, Khattak SF, Li ZJ, He A, Kayne PS, Patel V, Neuhaus IM, Sharfstein ST. Transcriptomic responses to sodium chloride-induced osmotic stress: a study of industrial fed-batch CHO cell cultures. Biotechnology Progress. 26: 1104-15. PMID 20306541 DOI: 10.1002/btpr.398  1
2009 Nam JH, Ermonval M, Sharfstein ST. The effects of microcarrier culture on recombinant CHO cells under biphasic hypothermic culture conditions. Cytotechnology. 59: 81-91. PMID 19412658 DOI: 10.1007/s10616-009-9196-x  0.44
2009 Jiang Z, Sharfstein ST. Characterization of gene localization and accessibility in DHFR-amplified CHO cells. Biotechnology Progress. 25: 296-300. PMID 19224609 DOI: 10.1002/btpr.82  1
2009 Barua S, Joshi A, Banerjee A, Matthews D, Sharfstein ST, Cramer SM, Kane RS, Rege K. Parallel synthesis and screening of polymers for nonviral gene delivery. Molecular Pharmaceutics. 6: 86-97. PMID 19102694 DOI: 10.1021/mp800151j  1
2008 Nam JH, Zhang F, Ermonval M, Linhardt RJ, Sharfstein ST. The effects of culture conditions on the glycosylation of secreted human placental alkaline phosphatase produced in Chinese hamster ovary cells Biotechnology and Bioengineering. 100: 1178-1192. PMID 18553404 DOI: 10.1002/bit.21853  1
2008 Sharfstein ST. Advances in cell culture process development: Tools and techniques for improving cell line development and process optimization Biotechnology Progress. 24: 727-734. PMID 18426245 DOI: 10.1021/bp070471q  1
2008 Jiang Z, Sharfstein ST. Sodium butyrate stimulates monoclonal antibody over-expression in CHO cells by improving gene accessibility. Biotechnology and Bioengineering. 100: 189-94. PMID 18023047 DOI: 10.1002/bit.21726  1
2007 Jong HN, Ermonval M, Sharfstein ST. Cell attachment to microcarriers affects growth, metabolic activity, and culture productivity in bioreactor culture Biotechnology Progress. 23: 652-660. PMID 17500530 DOI: 10.1021/bp070007l  1
2006 Jiang Z, Huang Y, Sharfstein ST. Regulation of recombinant monoclonal antibody production in Chinese hamster ovary cells: A comparative study of gene copy number, mRNA level, and protein expression Biotechnology Progress. 22: 313-318. PMID 16454525 DOI: 10.1021/bp0501524  1
2006 Shen D, Sharfstein ST. Genome-wide analysis of the transcriptional response of murine hybridomas to osmotic shock Biotechnology and Bioengineering. 93: 132-145. PMID 16196057 DOI: 10.1002/bit.20691  1
2005 McNeeley KM, Sun Z, Sharfstein ST. Techniques for dual staining of DNA and intracellular immunoglobulins in murine hybridoma cells: applications to cell-cycle analysis of hyperosmotic cultures. Cytotechnology. 48: 15-26. PMID 19003029 DOI: 10.1007/s10616-005-2926-9  1
2004 Sun Z, Zhou R, Liang S, McNeeley KM, Sharfstein ST. Hyperosmotic stress in murine hybridoma cells: effects on antibody transcription, translation, posttranslational processing, and the cell cycle. Biotechnology Progress. 20: 576-89. PMID 15059005 DOI: 10.1021/bp0342203  1
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