| Year |
Citation |
Score |
| 2023 |
Dym O, Aggarwal N, Ashani Y, Leader H, Albeck S, Unger T, Hamer-Rogotner S, Silman I, Tawfik DS, Sussman JL. The impact of molecular variants, crystallization conditions and the space group on ligand-protein complexes: a case study on bacterial phosphotriesterase. Acta Crystallographica. Section D, Structural Biology. 79: 992-1009. PMID 37860961 DOI: 10.1107/S2059798323007672 |
0.73 |
|
| 2023 |
Liu J, Yuan R, Shao W, Wang J, Silman I, Sussman JL. Do "Newly Born" orphan proteins resemble "Never Born" proteins? A study using three deep learning algorithms. Proteins. PMID 37092778 DOI: 10.1002/prot.26496 |
0.515 |
|
| 2023 |
Pokorna S, Khersonsky O, Lipsh-Sokolik R, Goldenzweig A, Nielsen R, Ashani Y, Peleg Y, Unger T, Albeck S, Dym O, Tirosh A, Tarayra R, Hocquemiller M, Laufer R, Ben-Dor S, ... ... Sussman JL, et al. Design of a stable human acid-β-glucosidase: towards improved Gaucher disease therapy and mutation classification. The Febs Journal. PMID 36808692 DOI: 10.1111/febs.16758 |
0.682 |
|
| 2021 |
Silman I, Shnyrov VL, Ashani Y, Roth E, Nicolas A, Sussman JL, Weiner L. Torpedo californica acetylcholinesterase is stabilized by binding of a divalent metal ion to a novel and versatile 4D motif. Protein Science : a Publication of the Protein Society. PMID 33686648 DOI: 10.1002/pro.4061 |
0.479 |
|
| 2021 |
Daniel E, Maksimainen MM, Smith N, Ratas V, Biterova E, Murthy SN, Rahman MT, Kiema TR, Sridhar S, Cordara G, Dalwani S, Venkatesan R, Prilusky J, Dym O, Lehtiö L, ... ... Sussman JL, et al. IceBear: an intuitive and versatile web application for research-data tracking from crystallization experiment to PDB deposition. Acta Crystallographica. Section D, Structural Biology. 77: 151-163. PMID 33559605 DOI: 10.1107/S2059798320015223 |
0.627 |
|
| 2020 |
Sussman JL, Silman I. Computational studies on cholinesterases: Strengthening our understanding of the integration of structure, dynamics and function. Neuropharmacology. 179: 108265. PMID 32795461 DOI: 10.1016/J.Neuropharm.2020.108265 |
0.56 |
|
| 2020 |
Orengo C, Velankar S, Wodak S, Zoete V, Bonvin AMJJ, Elofsson A, Feenstra KA, Gerloff DL, Hamelryck T, Hancock JM, Helmer-Citterich M, Hospital A, Orozco M, Perrakis A, Rarey M, ... ... Sussman JL, et al. A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community). F1000research. 9. PMID 32566135 DOI: 10.12688/F1000Research.20559.1 |
0.579 |
|
| 2020 |
Nachon F, Rosenberry TL, Silman I, Sussman JL. A Second Look at the Crystal Structures of Acetylcholinesterase in Complex with Tacrine Derivatives Provides Insights Concerning Catalytic Intermediates and the Design of Specific Insecticides. Molecules (Basel, Switzerland). 25. PMID 32155891 DOI: 10.3390/Molecules25051198 |
0.608 |
|
| 2020 |
Suzumoto Y, Dim O, Roviello GN, Worek F, Sussman JL, Manco G. Structural and Functional Characterization of New SsoPox Variant Points to the Dimer Interface as a Driver for the Increase in Promiscuous Paraoxonase Activity. International Journal of Molecular Sciences. 21. PMID 32121487 DOI: 10.3390/Ijms21051683 |
0.374 |
|
| 2020 |
Toker L, Silman I, Zeev-Ben-Mordehai T, Sussman JL, Schopfer LM, Lockridge O. Polyproline-rich peptides associated with Torpedo californica acetylcholinesterase tetramers. Chemico-Biological Interactions. 109007. PMID 32087110 DOI: 10.1016/J.Cbi.2020.109007 |
0.483 |
|
| 2020 |
Orengo C, Velankar S, Wodak S, Zoete V, Bonvin AM, Elofsson A, Feenstra KA, Gerloff DL, Hamelryck T, Hancock JM, Helmer-Citterich M, Hospital A, Orozco M, Perrakis A, Rarey M, ... ... Sussman JL, et al. A community proposal to integrate structural bioinformatics activities in ELIXIR (3D-Bioinfo Community) F1000research. 9: 278. DOI: 10.12688/f1000research.20559.1 |
0.53 |
|
| 2019 |
Ben-David M, Soskine M, Dubovetskyi A, Cherukuri KP, Dym O, Sussman JL, Liao Q, Szeler K, Kamerlin SCL, Tawfik DS. Enzyme neo- versus re-functionalization - an epistatic ratchet versus a smooth reversible transition. Molecular Biology and Evolution. PMID 31873734 DOI: 10.1093/Molbev/Msz298 |
0.667 |
|
| 2019 |
Chandar NB, Efremenko I, Silman I, Martin JML, Sussman JL. Molecular dynamics simulations of the interaction of Mouse and Torpedo acetylcholinesterase with covalent inhibitors explain their differential reactivity: Implications for drug design. Chemico-Biological Interactions. PMID 31226285 DOI: 10.1016/J.Cbi.2019.06.028 |
0.565 |
|
| 2019 |
Novichkova DA, Lushchekina SV, Dym O, Masson P, Silman I, Sussman JL. The four-helix bundle in cholinesterase dimers: Structural and energetic determinants of stability. Chemico-Biological Interactions. PMID 31202688 DOI: 10.1016/J.Cbi.2019.06.012 |
0.74 |
|
| 2019 |
Oukoloff K, Coquelle N, Bartolini M, Naldi M, Le Guevel R, Bach S, Josselin B, Ruchaud S, Catto M, Pisani L, Denora N, Iacobazzi RM, Silman I, Sussman JL, Buron F, et al. Design, biological evaluation and X-ray crystallography of nanomolar multifunctional ligands targeting simultaneously acetylcholinesterase and glycogen synthase kinase-3. European Journal of Medicinal Chemistry. 168: 58-77. PMID 30798053 DOI: 10.1016/J.Ejmech.2018.12.063 |
0.523 |
|
| 2018 |
Leung MR, van Bezouwen LS, Schopfer LM, Sussman JL, Silman I, Lockridge O, Zeev-Ben-Mordehai T. Cryo-EM structure of the native butyrylcholinesterase tetramer reveals a dimer of dimers stabilized by a superhelical assembly. Proceedings of the National Academy of Sciences of the United States of America. PMID 30538207 DOI: 10.1073/Pnas.1817009115 |
0.582 |
|
| 2018 |
Lalut J, Santoni G, Karila D, Lecoutey C, Davis A, Nachon F, Silman I, Sussman J, Weik M, Maurice T, Dallemagne P, Rochais C. Novel multitarget-directed ligands targeting acetylcholinesterase and σ receptors as lead compounds for treatment of Alzheimer's disease: Synthesis, evaluation, and structural characterization of their complexes with acetylcholinesterase. European Journal of Medicinal Chemistry. 162: 234-248. PMID 30447434 DOI: 10.1016/J.Ejmech.2018.10.064 |
0.537 |
|
| 2018 |
Santoni G, de Sousa J, De la Mora E, Dias J, Jean L, Sussman JL, Silman I, Renard PY, Brown RCD, Weik M, Baati R, Nachon F. Structure-based optimization of non-quaternary reactivators of acetylcholinesterase inhibited by organophosphorus nerve agents. Journal of Medicinal Chemistry. PMID 30125110 DOI: 10.1021/Acs.Jmedchem.8B00592 |
0.561 |
|
| 2018 |
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, et al. Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Molecular Cell. 70: 380. PMID 29677494 DOI: 10.1016/j.molcel.2018.03.035 |
0.701 |
|
| 2018 |
Zorbaz T, Braïki A, Marakovic N, Renou J, de la Mora E, Marek Hrvat N, Katalinic M, Silman I, Sussman JL, Mercey G, Gomez C, Mougeot R, Perez B, Baati R, Nachon F, et al. Potent 3-hydroxy-2-pyridine aldoxime reactivators of organophosphate-inhibited cholinesterases with predicted blood-brain barrier penetration. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29672968 DOI: 10.1002/Chem.201801394 |
0.531 |
|
| 2018 |
Schneider B, Orengo C, Schwede T, Sussman JL, Thornton JM, Velankar S, Wodak S. Coordination of structural bioinformatics activities across Europe Acta Crystallographica Section a Foundations and Advances. 74: e231-e231. DOI: 10.7490/F1000Research.1115607.1 |
0.597 |
|
| 2017 |
Xu Y, Cheng S, Sussman JL, Silman I, Jiang H. Computational Studies on Acetylcholinesterases. Molecules (Basel, Switzerland). 22. PMID 28796192 DOI: 10.3390/Molecules22081324 |
0.571 |
|
| 2017 |
Faraggi E, Dunker K, Sussman J, Kloczkowski A. Comparing NMR and X-ray protein structure: Lindemann-like parameters and NMR disorder. Journal of Biomolecular Structure & Dynamics. 1-34. PMID 28714803 DOI: 10.1080/07391102.2017.1352539 |
0.326 |
|
| 2017 |
Silman I, Sussman JL. Recent developments in structural studies on acetylcholinesterase. Journal of Neurochemistry. PMID 28503857 DOI: 10.1111/Jnc.13992 |
0.615 |
|
| 2017 |
Sussman JL, Silman I. Recent breakthroughs in the structure/function studies of acetylcholinesterase Acta Crystallographica Section a Foundations and Advances. 73: C275-C275. DOI: 10.1107/S2053273317092981 |
0.554 |
|
| 2016 |
Goldenzweig A, Goldsmith M, Hill SE, Gertman O, Laurino P, Ashani Y, Dym O, Unger T, Albeck S, Prilusky J, Lieberman RL, Aharoni A, Silman I, Sussman JL, Tawfik DS, et al. Automated Structure- and Sequence-Based Design of Proteins for High Bacterial Expression and Stability. Molecular Cell. PMID 27425410 DOI: 10.1016/J.Molcel.2016.06.012 |
0.737 |
|
| 2016 |
Ashani Y, Leader H, Aggarwal N, Silman I, Worek F, Sussman JL, Goldsmith M. In vitro evaluation of the catalytic activity of paraoxonases and phosphotriesterases predicts the enzyme circulatory levels required for in vivo protection against organophosphate intoxications. Chemico-Biological Interactions. PMID 27163850 DOI: 10.1016/J.Cbi.2016.04.039 |
0.517 |
|
| 2016 |
Dym O, Song W, Felder C, Roth E, Shnyrov V, Ashani Y, Xu Y, Joosten RP, Weiner L, Sussman JL, Silman I. The Impact of Crystallization Conditions on Structure-Based Drug Design: A Case Study on the Methylene Blue/Acetylcholinesterase Complex. Protein Science : a Publication of the Protein Society. PMID 26990888 DOI: 10.1002/Pro.2923 |
0.749 |
|
| 2015 |
Ben-David M, Sussman JL, Maxwell CI, Szeler K, Kamerlin SC, Tawfik DS. Catalytic stimulation by restrained active-site floppiness--the case of high density lipoprotein-bound serum paraoxonase-1. Journal of Molecular Biology. 427: 1359-74. PMID 25644661 DOI: 10.1016/J.Jmb.2015.01.013 |
0.343 |
|
| 2015 |
Sussman JL, Prilusky J. Proteopedia- a scientific 'Wiki' bridging the rift between 3D structure and function of biomacromolecules Acta Crystallographica Section a Foundations and Advances. 71: s41-s41. DOI: 10.1107/S2053273315099350 |
0.31 |
|
| 2014 |
Varadi M, Kosol S, Lebrun P, Valentini E, Blackledge M, Dunker AK, Felli IC, Forman-Kay JD, Kriwacki RW, Pierattelli R, Sussman J, Svergun DI, Uversky VN, Vendruscolo M, Wishart D, et al. pE-DB: a database of structural ensembles of intrinsically disordered and of unfolded proteins. Nucleic Acids Research. 42: D326-35. PMID 24174539 DOI: 10.1093/Nar/Gkt960 |
0.375 |
|
| 2014 |
Sussman J, Prilusky J. Proteopedia: Bridging the Rift Between 3D Structure & Function of Biomacromolecules Acta Crystallographica Section a Foundations and Advances. 70: C1388-C1388. DOI: 10.1107/S2053273314086112 |
0.332 |
|
| 2013 |
Ben-David M, Wieczorek G, Elias M, Silman I, Sussman JL, Tawfik DS. Catalytic metal ion rearrangements underline promiscuity and evolvability of a metalloenzyme. Journal of Molecular Biology. 425: 1028-38. PMID 23318950 DOI: 10.1016/J.Jmb.2013.01.009 |
0.552 |
|
| 2013 |
Silman I, Roth E, Paz A, Triquigneaux MM, Ehrenshaft M, Xu Y, Shnyrov VL, Sussman JL, Deterding LJ, Ashani Y, Mason RP, Weiner L. The specific interaction of the photosensitizer methylene blue with acetylcholinesterase provides a model system for studying the molecular consequences of photodynamic therapy. Chemico-Biological Interactions. 203: 63-6. PMID 23159732 DOI: 10.1016/J.Cbi.2012.10.021 |
0.551 |
|
| 2013 |
Offman MN, Silman I, Sussman JL, Futerman AH. Crystal structure of the enzyme acid b-glucosidase Advances in Gaucher Disease: Basic and Clinical Perspectives. 125-138. DOI: 10.2217/EBO.12.215 |
0.504 |
|
| 2013 |
Celniker G, Nimrod G, Ashkenazy H, Glaser F, Martz E, Mayrose I, Pupko T, Ben-Tal N, Hanson RM, Prilusky J, Renjian Z, Nakane T, Sussman JL. Cover Picture: ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function / JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied toProteopedia(Isr. J. Chem. 3-4/2013) Israel Journal of Chemistry. 53: 137-137. DOI: 10.1002/Ijch.201390002 |
0.341 |
|
| 2013 |
Prilusky J, Sussman JL. Guest editorial: Databases and bioinformatics tools Israel Journal of Chemistry. 53: 143. DOI: 10.1002/Ijch.201310004 |
0.344 |
|
| 2012 |
Paz A, Roth E, Ashani Y, Xu Y, Shnyrov VL, Sussman JL, Silman I, Weiner L. Structural and functional characterization of the interaction of the photosensitizing probe methylene blue with Torpedo californica acetylcholinesterase. Protein Science : a Publication of the Protein Society. 21: 1138-52. PMID 22674800 DOI: 10.1002/Pro.2101 |
0.566 |
|
| 2012 |
Goldsmith M, Ashani Y, Simo Y, Ben-David M, Leader H, Silman I, Sussman JL, Tawfik DS. Evolved stereoselective hydrolases for broad-spectrum G-type nerve agent detoxification. Chemistry & Biology. 19: 456-66. PMID 22520752 DOI: 10.1016/J.Chembiol.2012.01.017 |
0.497 |
|
| 2012 |
Greenblatt HM, Otto TC, Kirkpatrick MG, Kovaleva E, Brown S, Buchman G, Cerasoli DM, Sussman JL. Structure of recombinant human carboxylesterase 1 isolated from whole cabbage looper larvae. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 269-72. PMID 22442219 DOI: 10.1107/S1744309112003326 |
0.356 |
|
| 2012 |
Ben-David M, Elias M, Filippi JJ, Duñach E, Silman I, Sussman JL, Tawfik DS. Catalytic versatility and backups in enzyme active sites: the case of serum paraoxonase 1. Journal of Molecular Biology. 418: 181-96. PMID 22387469 DOI: 10.1016/J.Jmb.2012.02.042 |
0.576 |
|
| 2012 |
Khare SD, Kipnis Y, Greisen P, Takeuchi R, Ashani Y, Goldsmith M, Song Y, Gallaher JL, Silman I, Leader H, Sussman JL, Stoddard BL, Tawfik DS, Baker D. Computational redesign of a mononuclear zinc metalloenzyme for organophosphate hydrolysis. Nature Chemical Biology. 8: 294-300. PMID 22306579 DOI: 10.1038/Nchembio.777 |
0.559 |
|
| 2012 |
Xu Y, Li MJ, Greenblatt H, Chen W, Paz A, Dym O, Peleg Y, Chen T, Shen X, He J, Jiang H, Silman I, Sussman JL. Flexibility of the flap in the active site of BACE1 as revealed by crystal structures and molecular dynamics simulations. Acta Crystallographica. Section D, Biological Crystallography. 68: 13-25. PMID 22194329 DOI: 10.1107/S0907444911047251 |
0.771 |
|
| 2012 |
Wood K, Paz A, Dijkstra K, Scheek RM, Otten R, Silman I, Sussman JL, Mulder FA. Backbone and side chain NMR assignments for the intrinsically disordered cytoplasmic domain of human neuroligin-3. Biomolecular Nmr Assignments. 6: 15-8. PMID 21647611 DOI: 10.1007/S12104-011-9315-4 |
0.493 |
|
| 2011 |
Ashani Y, Goldsmith M, Leader H, Silman I, Sussman JL, Tawfik DS. In vitro detoxification of cyclosarin in human blood pre-incubated ex vivo with recombinant serum paraoxonases. Toxicology Letters. 206: 24-8. PMID 21807078 DOI: 10.1016/J.Toxlet.2011.07.017 |
0.492 |
|
| 2011 |
Offman MN, Krol M, Rost B, Silman I, Sussman JL, Futerman AH. Comparison of a molecular dynamics model with the X-ray structure of the N370S acid-beta-glucosidase mutant that causes Gaucher disease. Protein Engineering, Design & Selection : Peds. 24: 773-5. PMID 21724649 DOI: 10.1093/Protein/Gzr032 |
0.561 |
|
| 2011 |
Perrakis A, Daenke S, Stuart DI, Sussman JL. From SPINE to SPINE-2 complexes and beyond Journal of Structural Biology. 175: 105. PMID 21619933 DOI: 10.1016/J.Jsb.2011.05.013 |
0.32 |
|
| 2011 |
Sanson B, Colletier JP, Xu Y, Lang PT, Jiang H, Silman I, Sussman JL, Weik M. Backdoor opening mechanism in acetylcholinesterase based on X-ray crystallography and molecular dynamics simulations Protein Science. 20: 1114-1118. PMID 21594947 DOI: 10.1002/Pro.661 |
0.589 |
|
| 2011 |
Suskiewicz MJ, Sussman JL, Silman I, Shaul Y. Context-dependent resistance to proteolysis of intrinsically disordered proteins Protein Science. 20: 1285-1297. PMID 21574196 DOI: 10.1002/Pro.657 |
0.528 |
|
| 2011 |
Prilusky J, Hodis E, Canner D, Decatur WA, Oberholser K, Martz E, Berchanski A, Harel M, Sussman JL. Proteopedia: A status report on the collaborative, 3D web-encyclopedia of proteins and other biomolecules Journal of Structural Biology. 175: 244-252. PMID 21536137 DOI: 10.1016/J.Jsb.2011.04.011 |
0.341 |
|
| 2011 |
Brumshtein B, Aguilar-Moncayo M, Benito JM, García Fernandez JM, Silman I, Shaaltiel Y, Aviezer D, Sussman JL, Futerman AH, Ortiz Mellet C. Cyclodextrin-mediated crystallization of acid β-glucosidase in complex with amphiphilic bicyclic nojirimycin analogues Organic and Biomolecular Chemistry. 9: 4160-4167. PMID 21483943 DOI: 10.1039/C1Ob05200D |
0.538 |
|
| 2011 |
Li MJ, Greenblatt HM, Dym O, Albeck S, Pais A, Gunanathan C, Milstein D, Degani H, Sussman JL. Structure of estradiol metal chelate and estrogen receptor complex: the basis for designing a new class of selective estrogen receptor modulators. Journal of Medicinal Chemistry. 54: 3575-80. PMID 21473635 DOI: 10.1021/Jm200192Y |
0.636 |
|
| 2011 |
Busso D, Peleg Y, Heidebrecht T, Romier C, Jacobovitch Y, Dantes A, Salim L, Troesch E, Schuetz A, Heinemann U, Folkers GE, Geerlof A, Wilmanns M, Polewacz A, Quedenau C, ... ... Sussman JL, et al. Expression of protein complexes using multiple Escherichia coli protein co-expression systems: a benchmarking study. Journal of Structural Biology. 175: 159-70. PMID 21382497 DOI: 10.1016/J.Jsb.2011.03.004 |
0.315 |
|
| 2011 |
Gupta RD, Goldsmith M, Ashani Y, Simo Y, Mullokandov G, Bar H, Ben-David M, Leader H, Margalit R, Silman I, Sussman JL, Tawfik DS. Directed evolution of hydrolases for prevention of G-type nerve agent intoxication. Nature Chemical Biology. 7: 120-5. PMID 21217689 DOI: 10.1038/Nchembio.510 |
0.504 |
|
| 2010 |
Hodis E, Prilusky J, Sussman JL. Proteopedia: A collaborative, virtual 3D web-resource for protein and biomolecule structure and function. Biochemistry and Molecular Biology Education : a Bimonthly Publication of the International Union of Biochemistry and Molecular Biology. 38: 341-2. PMID 21567857 DOI: 10.1002/Bmb.20431 |
0.368 |
|
| 2010 |
Xu Y, Colletier JP, Weik M, Qin G, Jiang H, Silman I, Sussman JL. Long route or shortcut? A molecular dynamics study of traffic of thiocholine within the active-site gorge of acetylcholinesterase Biophysical Journal. 99: 4003-4011. PMID 21156143 DOI: 10.1016/J.Bpj.2010.10.047 |
0.544 |
|
| 2010 |
Offman MN, Krol M, Silman I, Sussman JL, Futerman AH. Molecular basis of reduced glucosylceramidase activity in the most common Gaucher disease mutant, N370S Journal of Biological Chemistry. 285: 42105-42114. PMID 20980259 DOI: 10.1074/Jbc.M110.172098 |
0.593 |
|
| 2010 |
Ashani Y, Gupta RD, Goldsmith M, Silman I, Sussman JL, Tawfik DS, Leader H. Stereo-specific synthesis of analogs of nerve agents and their utilization for selection and characterization of paraoxonase (PON1) catalytic scavengers. Chemico-Biological Interactions. 187: 362-9. PMID 20303930 DOI: 10.1016/J.Cbi.2010.02.039 |
0.496 |
|
| 2010 |
Dvir H, Silman I, Harel M, Rosenberry TL, Sussman JL. Acetylcholinesterase: From 3D structure to function Chemico-Biological Interactions. 187: 10-22. PMID 20138030 DOI: 10.1016/J.Cbi.2010.01.042 |
0.61 |
|
| 2010 |
Brumshtein B, Salinas P, Peterson B, Chan V, Silman I, Sussman JL, Savickas PJ, Robinson GS, Futerman AH. Characterization of gene-activated human acid-β-glucosidase: Crystal structure, glycan composition, and internalization into macrophages Glycobiology. 20: 24-32. PMID 19741058 DOI: 10.1093/Glycob/Cwp138 |
0.59 |
|
| 2010 |
Paz A, Zeev-Ben-Mordehai T, Sussman JL, Silman I. Purification of Intrinsically Disordered Proteins Instrumental Analysis of Intrinsically Disordered Proteins: Assessing Structure and Conformation. 695-704. DOI: 10.1002/9780470602614.ch24 |
0.422 |
|
| 2009 |
Zeev-Ben-Mordehai T, Mylonas E, Paz A, Peleg Y, Toker L, Silman I, Svergun DI, Sussman JL. The quaternary structure of amalgam, a Drosophila neuronal adhesion protein, explains its dual adhesion properties. Biophysical Journal. 97: 2316-26. PMID 19843464 DOI: 10.1016/J.Bpj.2009.07.045 |
0.559 |
|
| 2009 |
Ben-David M, Noivirt-Brik O, Paz A, Prilusky J, Sussman JL, Levy Y. Assessment of CASP8 structure predictions for template free targets. Proteins. 77: 50-65. PMID 19774550 DOI: 10.1002/Prot.22591 |
0.319 |
|
| 2009 |
Sharabi O, Peleg Y, Mashiach E, Vardy E, Ashani Y, Simian I, Sussman JL, Shifman JM. Design, expression and characterization of mutants of fasciculin optimized for interaction with its target, acetylcholinesterase Protein Engineering, Design and Selection. 22: 641-648. PMID 19643977 DOI: 10.1093/Protein/Gzp045 |
0.345 |
|
| 2009 |
Sanson B, Nachon F, Colletier JP, Froment MT, Toker L, Greenblatt HM, Sussman JL, Ashani Y, Masson P, Silman I, Weik M. Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime Journal of Medicinal Chemistry. 52: 7593-7603. PMID 19642642 DOI: 10.1021/Jm900433T |
0.564 |
|
| 2009 |
Khersonsky O, Rosenblat M, Toker L, Yacobson S, Hugenmatter A, Silman I, Sussman JL, Aviram M, Tawfik DS. Directed evolution of serum paraoxonase PON3 by family shuffling and ancestor/consensus mutagenesis, and its biochemical characterization Biochemistry. 48: 6644-6654. PMID 19492856 DOI: 10.1021/Bi900583Y |
0.527 |
|
| 2009 |
Brumshtein B, Aguilar-Moncayo M, García-Moreno IM, Mellet CO, Fernández JGM, Silman I, Shaaltiel Y, Aviezer D, Sussman JL, Futerman AH. 6-Amino-6-deoxy-5,6-di-N-(N′-octyliminomethylidene) nojirimycin: Synthesis, biological evaluation, and crystal structure in complex with acid β-glucosidase Chembiochem. 10: 1480-1485. PMID 19437524 DOI: 10.1002/Cbic.200900142 |
0.528 |
|
| 2009 |
Paz A, Xie Q, Greenblatt HM, Fu W, Tang Y, Silman I, Qiu Z, Sussman JL. The crystal structure of a complex of acetylcholinesterase with a bis-(-)-nor-meptazinol derivative reveals disruption of the catalytic triad. Journal of Medicinal Chemistry. 52: 2543-9. PMID 19326912 DOI: 10.1021/Jm801657V |
0.628 |
|
| 2009 |
Zeev-Ben-Mordehai T, Paz A, Peleg Y, Toker L, Wolf SG, Rydberg EH, Sussman JL, Silman I. Amalgam, an axon guidance Drosophila adhesion protein belonging to the immunoglobulin superfamily: over-expression, purification and biophysical characterization. Protein Expression and Purification. 63: 147-57. PMID 18938249 DOI: 10.1016/J.Pep.2008.09.019 |
0.536 |
|
| 2009 |
Sussman JL, Hodis E, Silman I, Moult J, Martz E, Prilusky J. Proteopedia: scientific wiki bridging 3D structure-function Acta Crystallographica Section a Foundations of Crystallography. 65: s39-s39. DOI: 10.1107/S0108767309099255 |
0.529 |
|
| 2008 |
Brumshtein B, Greenblatt HM, Futerman AH, Silman I, Sussman JL. Control of the rate of evaporation in protein crystallization by the 'microbatch under oil' method. Journal of Applied Crystallography. 41: 969-971. PMID 19461852 DOI: 10.1107/S0021889808024667 |
0.507 |
|
| 2008 |
Dunker AK, Silman I, Uversky VN, Sussman JL. Function and structure of inherently disordered proteins Current Opinion in Structural Biology. 18: 756-764. PMID 18952168 DOI: 10.1016/J.Sbi.2008.10.002 |
0.59 |
|
| 2008 |
Kacher Y, Brumshtein B, Boldin-Adamsky S, Toker L, Shainskaya A, Silman I, Sussman JL, Futerman AH. Acid β-glucosidase: Insights from structural analysis and relevance to Gaucher disease therapy Biological Chemistry. 389: 1361-1369. PMID 18783340 DOI: 10.1515/Bc.2008.163 |
0.552 |
|
| 2008 |
Colletier JP, Bourgeois D, Sanson B, Fournier D, Sussman JL, Silman I, Weik M. Shoot-and-trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography Proceedings of the National Academy of Sciences of the United States of America. 105: 11742-11747. PMID 18701720 DOI: 10.1073/Pnas.0804828105 |
0.586 |
|
| 2008 |
Hodis E, Prilusky J, Martz E, Silman I, Moult J, Sussman JL. Proteopedia - A scientific 'wiki' bridging the rift between three-dimensional structure and function of biomacromolecules Genome Biology. 9. PMID 18673581 DOI: 10.1186/Gb-2008-9-8-R121 |
0.56 |
|
| 2008 |
Silman I, Sussman JL. Acetylcholinesterase: How is structure related to function? Chemico-Biological Interactions. 175: 3-10. PMID 18586019 DOI: 10.1016/J.Cbi.2008.05.035 |
0.59 |
|
| 2008 |
Meged R, Dym O, Sussman JL. High throughput pH optimization of protein crystallization. Methods in Molecular Biology (Clifton, N.J.). 426: 411-418. PMID 18542880 DOI: 10.1007/978-1-60327-058-8_27 |
0.656 |
|
| 2008 |
Harel M, Sonoda LK, Silman I, Sussman JL, Rosenberry TL. Crystal structure of thioflavin T bound to the peripheral site of Torpedo californica acetylcholinesterase reveals how thioflavin T acts as a sensitive fluorescent reporter of ligand binding to the acylation site Journal of the American Chemical Society. 130: 7856-7861. PMID 18512913 DOI: 10.1021/Ja7109822 |
0.566 |
|
| 2008 |
Xu Y, Colletier JP, Weik M, Jiang H, Moult J, Silman I, Sussman JL. Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics Biophysical Journal. 95: 2500-2511. PMID 18502801 DOI: 10.1529/Biophysj.108.129601 |
0.591 |
|
| 2008 |
Paz A, Zeev-Ben-Mordehai T, Lundqvist M, Sherman E, Mylonas E, Weiner L, Haran G, Svergun DI, Mulder FA, Sussman JL, Silman I. Biophysical characterization of the unstructured cytoplasmic domain of the human neuronal adhesion protein neuroligin 3. Biophysical Journal. 95: 1928-44. PMID 18456828 DOI: 10.1529/Biophysj.107.126995 |
0.521 |
|
| 2008 |
Manicka S, Peleg Y, Unger T, Albeck S, Dym O, Greenblatt HM, Bourenkov G, Lamzin V, Krishnaswamy S, Sussman JL. Crystal structure of YagE, a putative DHDPS-like protein from Escherichia coli K12. Proteins. 71: 2102-8. PMID 18361457 DOI: 10.1002/Prot.22023 |
0.671 |
|
| 2008 |
Xu Y, Colletier JP, Jiang H, Silman I, Sussman JL, Weik M. Induced-fit or preexisting equilibrium dynamics? Lessons from protein crystallography and MD simulations on acetylcholinesterase and implications for structure-based drug design Protein Science. 17: 601-605. PMID 18359854 DOI: 10.1110/Ps.083453808 |
0.569 |
|
| 2008 |
Gräslund S, Nordlund P, Weigelt J, Hallberg BM, Bray J, Gileadi O, Knapp S, Oppermann U, Arrowsmith C, Hui R, Ming J, dhe-Paganon S, ... ... Sussman JL, et al. Protein production and purification. Nature Methods. 5: 135-46. PMID 18235434 DOI: 10.1038/Nmeth.F.202 |
0.706 |
|
| 2008 |
Tompa P, Prilusky J, Silman I, Sussman JL. Structural disorder serves as a weak signal for intracellular protein degradation Proteins: Structure, Function and Genetics. 71: 903-909. PMID 18004785 DOI: 10.1002/Prot.21773 |
0.535 |
|
| 2008 |
Tsvetkov P, Asher G, Paz A, Reuven N, Sussman JL, Silman I, Shaul Y. Operational definition of intrinsically unstructured protein sequences based on susceptibility to the 20S proteasome Proteins: Structure, Function and Genetics. 70: 1357-1366. PMID 17879262 DOI: 10.1002/Prot.21614 |
0.546 |
|
| 2008 |
Brumshtein B, Greenblatt HM, Futerman AH, Silman I, Sussman JL. Control of the rate of evaporation in protein crystallization by the 'microbatch under oil' method Journal of Applied Crystallography. 41: 969-971. DOI: 10.1107/S0021889808024667 |
0.435 |
|
| 2007 |
Colletier JP, Royant A, Specht A, Sanson B, Nachon F, Masson P, Zaccai G, Sussman JL, Goeldner M, Silman I, Bourgeois D, Weik M. Use of a 'caged' analogue to study the traffic of choline within acetylcholinesterase by kinetic crystallography. Acta Crystallographica. Section D, Biological Crystallography. 63: 1115-28. PMID 18007027 DOI: 10.1107/S0907444907044472 |
0.579 |
|
| 2007 |
Banci L, Baumeister W, Heinemann U, Schneider G, Silman I, Stuart DI, Sussman JL. An idea whose time has come. Genome Biology. 8: 408. PMID 18001498 DOI: 10.1186/Gb-2007-8-11-408 |
0.601 |
|
| 2007 |
Harel M, Brumshtein B, Meged R, Dvir H, Ravelli RBG, McCarthy A, Toker L, Silman I, Sussman JL. 3-D structure of serum paraoxonase 1 sheds light on its activity, stability, solubility and crystallizability Arhiv Za Higijenu Rada I Toksikologiju. 58: 347-353. PMID 17913690 DOI: 10.2478/V10004-007-0028-0 |
0.577 |
|
| 2007 |
Brumshtein B, Greenblatt HM, Butters TD, Shaaltiel Y, Aviezer D, Silman I, Futerman AH, Sussman JL. Crystal structures of complexes of N-butyl- and N-nonyl-deoxynojirimycin bound to acid β-glucosidase: Insights into the mechanism of chemical chaperone action in Gaucher disease Journal of Biological Chemistry. 282: 29052-29058. PMID 17666401 DOI: 10.1074/Jbc.M705005200 |
0.601 |
|
| 2007 |
Felder CE, Prilusky J, Silman I, Sussman JL. A server and database for dipole moments of proteins. Nucleic Acids Research. 35: W512-21. PMID 17526523 DOI: 10.1093/Nar/Gkm307 |
0.543 |
|
| 2007 |
Shaaltiel Y, Bartfeld D, Hashmueli S, Baum G, Brill-Almon E, Galili G, Dym O, Boldin-Adamsky SA, Silman I, Sussman JL, Futerman AH, Aviezer D. Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system. Plant Biotechnology Journal. 5: 579-90. PMID 17524049 DOI: 10.1111/J.1467-7652.2007.00263.X |
0.724 |
|
| 2007 |
Haviv H, Wong DM, Silman I, Sussman JL. Bivalent ligands derived from Huperzine A as acetylcholinesterase inhibitors Current Topics in Medicinal Chemistry. 7: 375-387. PMID 17305579 DOI: 10.2174/156802607779941215 |
0.575 |
|
| 2007 |
Banci L, Baumeister W, Enfedaque J, Heinemann U, Schneider G, Silman I, Sussman JL. Structural proteomics: from the molecule to the system. Nature Structural & Molecular Biology. 14: 3-4. PMID 17203065 DOI: 10.1038/Nsmb0107-3 |
0.571 |
|
| 2007 |
Shaaltiel Y, Bartfeld D, Hashmueli S, Baum G, Brill-Almon E, Galili G, Dym O, Boldin-Adamsky SA, Silman I, Sussman JL, Futerman AH, Aviezer D. Production of glucocerebrosidase with terminal mannose glycans for enzyme replacement therapy of Gaucher's disease using a plant cell system Plant Biotechnology Journal. 5: 579-590. DOI: 10.1111/j.1467-7652.2007.00263.x |
0.429 |
|
| 2007 |
Sanson B, Nachon F, Colletier J, Silman I, Sussman JL, Masson P, Weik M. Crystal structures of conjugates of soman withTcAChE Acta Crystallographica Section a Foundations of Crystallography. 63: s122-s123. DOI: 10.1107/S0108767307097334 |
0.517 |
|
| 2007 |
Felder CE, Prilusky J, Silman I, Sussman JL. A server and database for dipole moments of proteins Nucleic Acids Research. 35: W512-W521. DOI: 10.1093/nar/gkm307 |
0.444 |
|
| 2006 |
Brumshtein B, Wormald MR, Silman I, Futerman AH, Sussman JL. Structural comparison of differently glycosylated forms of acid-β-glucosidase, the defective enzyme in Gaucher disease Acta Crystallographica Section D: Biological Crystallography. 62: 1458-1465. PMID 17139081 DOI: 10.1107/S0907444906038303 |
0.602 |
|
| 2006 |
Esnouf RM, Hamer R, Sussman JL, Silman I, Trudgian D, Yang ZR, Prilusky J. Honing the in silico toolkit for detecting protein disorder Acta Crystallographica Section D: Biological Crystallography. 62: 1260-1266. PMID 17001103 DOI: 10.1107/S0907444906033580 |
0.535 |
|
| 2006 |
Romier C, Ben Jelloul M, Albeck S, Buchwald G, Busso D, Celie PH, Christodoulou E, De Marco V, van Gerwen S, Knipscheer P, Lebbink JH, Notenboom V, Poterszman A, Rochel N, Cohen SX, ... ... Sussman JL, et al. Co-expression of protein complexes in prokaryotic and eukaryotic hosts: experimental procedures, database tracking and case studies. Acta Crystallographica. Section D, Biological Crystallography. 62: 1232-42. PMID 17001100 DOI: 10.1107/S0907444906031003 |
0.312 |
|
| 2006 |
Banci L, Bertini I, Cusack S, de Jong RN, Heinemann U, Jones EY, Kozielski F, Maskos K, Messerschmidt A, Owens R, Perrakis A, Poterszman A, Schneider G, Siebold C, Silman I, ... ... Sussman JL, et al. First steps towards effective methods in exploiting high-throughput technologies for the determination of human protein structures of high biomedical value. Acta Crystallographica. Section D, Biological Crystallography. 62: 1208-17. PMID 17001097 DOI: 10.1107/S0907444906029350 |
0.576 |
|
| 2006 |
Albeck S, Alzari P, Andreini C, Banci L, Berry IM, Bertini I, Cambillau C, Canard B, Carter L, Cohen SX, Diprose JM, Dym O, Esnouf RM, Felder C, Ferron F, ... ... Sussman JL, et al. SPINE bioinformatics and data-management aspects of high-throughput structural biology. Acta Crystallographica. Section D, Biological Crystallography. 62: 1184-95. PMID 17001095 DOI: 10.1107/S090744490602991X |
0.524 |
|
| 2006 |
Berry IM, Dym O, Esnouf RM, Harlos K, Meged R, Perrakis A, Sussman JL, Walter TS, Wilson J, Messerschmidt A. SPINE high-throughput crystallization, crystal imaging and recognition techniques: Current state, performance analysis, new technologies and future aspects Acta Crystallographica Section D: Biological Crystallography. 62: 1137-1149. PMID 17001091 DOI: 10.1107/S090744490602943X |
0.316 |
|
| 2006 |
Aricescu AR, Assenberg R, Bill RM, Busso D, Chang VT, Davis SJ, Dubrovsky A, Gustafsson L, Hedfalk K, Heinemann U, Jones IM, Ksiazek D, Lang C, Maskos K, Messerschmidt A, ... ... Sussman JL, et al. Eukaryotic expression: developments for structural proteomics. Acta Crystallographica. Section D, Biological Crystallography. 62: 1114-24. PMID 17001089 DOI: 10.1107/S0907444906029805 |
0.307 |
|
| 2006 |
Rydberg EH, Brumshtein B, Greenblatt HM, Wong DM, Shaya D, Williams LD, Carlier PR, Pang YP, Silman I, Sussman JL. Complexes of alkylene-linked tacrine dimers with Torpedo californica acetylcholinesterase: Binding of Bis5-tacrine produces a dramatic rearrangement in the active-site gorge. Journal of Medicinal Chemistry. 49: 5491-500. PMID 16942022 DOI: 10.1021/Jm060164B |
0.597 |
|
| 2006 |
Colletier JP, Fournier D, Greenblatt HM, Stojan J, Sussman JL, Zaccai G, Silman I, Weik M. Structural insights into substrate traffic and inhibition in acetylcholinesterase Embo Journal. 25: 2746-2756. PMID 16763558 DOI: 10.1038/Sj.Emboj.7601175 |
0.58 |
|
| 2006 |
Sussman JL, Silman I. Shedding UV Light on the Phase Problem Structure. 14: 629-630. PMID 16615902 DOI: 10.1016/J.Str.2006.03.004 |
0.496 |
|
| 2006 |
Peleg Y, Albeck S, Burstein Y, Dym O, Jacobovitch Y, Levy N, Meged R, Michael Y, Prilusky J, Schreiber G, Silman I, Unger T, Sussman JL. Microbial Cell Factories. 5: P40. DOI: 10.1186/1475-2859-5-S1-P40 |
0.569 |
|
| 2006 |
Sussman JL, Lin D, Jiang J-, Manning NO, Prilusky J, Abola EE. The Protein Data Bank at Brookhaven International Tables For Crystallography. 649-656. DOI: 10.1107/97809553602060000718 |
0.559 |
|
| 2006 |
Sussman J, Aharoni A, Harel M, Gaidukov L, Brumshtein B, Khersonsky O, Yagur S, Toker L, Silman I, Tawfik D. 3D structure of mammalian paraoxonase at 2.2Å resolution Toxicology Letters. 164: S9. DOI: 10.1016/J.Toxlet.2006.06.024 |
0.541 |
|
| 2005 |
Niu C, Xu Y, Xu Y, Luo X, Duan W, Silman I, Sussman JL, Zhu W, Chen K, Shen J, Jiang H. Dynamic mechanism of E2020 binding to acetylcholinesterase: a steered molecular dynamics simulation. The Journal of Physical Chemistry. B. 109: 23730-8. PMID 16375354 DOI: 10.1021/Jp0552877 |
0.524 |
|
| 2005 |
Harel M, Hyatt JL, Brumshtein B, Morton CL, Wadkins RM, Silman I, Sussman JL, Potter PM. The 3D structure of the anticancer prodrug CPT-11 with Torpedo californica acetylcholinesterase rationalizes its inhibitory action on AChE and its hydrolysis by butyrylcholinesterase and carboxylesterase Chemico-Biological Interactions. 157: 153-157. PMID 16289500 DOI: 10.1016/J.Cbi.2005.10.016 |
0.603 |
|
| 2005 |
Hyatt JL, Tsurkan L, Morton CL, Yoon KJ, Harel M, Brumshtein B, Silman I, Sussman JL, Wadkins RM, Potter PM. Inhibition of acetylcholinesterase by the anticancer prodrug CPT-11. Chemico-Biological Interactions. 157: 247-52. PMID 16257398 DOI: 10.1016/J.Cbi.2005.10.033 |
0.531 |
|
| 2005 |
Albeck S, Burstein Y, Dym O, Jacobovitch Y, Levi N, Meged R, Michael Y, Peleg Y, Prilusky J, Schreiber G, Silman I, Unger T, Sussman JL. Three-dimensional structure determination of proteins related to human health in their functional context at the Israel Structural Proteomics Center (ISPC) Acta Crystallographica Section D: Biological Crystallography. 61: 1364-1372. PMID 16204888 DOI: 10.1107/S0907444905023565 |
0.74 |
|
| 2005 |
Haviv H, Wong DM, Greenblatt HM, Carlier PR, Pang YP, Silman I, Sussman JL. Crystal packing mediates enantioselective ligand recognition at the peripheral site of acetylcholinesterase Journal of the American Chemical Society. 127: 11029-11036. PMID 16076210 DOI: 10.1021/Ja051765F |
0.604 |
|
| 2005 |
Hasin Y, Avidan N, Bercovich D, Korczyn AD, Silman I, Beckmann JS, Sussman JL. Analysis of genetic polymorphisms in acetylcholinesterase as reflected in different populations. Current Alzheimer Research. 2: 207-18. PMID 15974920 DOI: 10.2174/1567205053585909 |
0.509 |
|
| 2005 |
Prilusky J, Felder CE, Zeev-Ben-Mordehai T, Rydberg EH, Man O, Beckmann JS, Silman I, Sussman JL. FoldIndex©: A simple tool to predict whether a given protein sequence is intrinsically unfolded Bioinformatics. 21: 3435-3438. PMID 15955783 DOI: 10.1093/Bioinformatics/Bti537 |
0.521 |
|
| 2005 |
Prilusky J, Oueillet E, Ulryck N, Pajon A, Bernauer J, Krimm I, Quevillon-Cheruel S, Leulliot N, Graille M, Liger D, Trésaugues L, Sussman JL, Janin J, van Tilbeurgh H, Poupon A. HalX: an open-source LIMS (Laboratory Information Management System) for small- to large-scale laboratories. Acta Crystallographica. Section D, Biological Crystallography. 61: 671-8. PMID 15930618 DOI: 10.1107/S0907444905001290 |
0.368 |
|
| 2005 |
Silman I, Sussman JL. Acetylcholinesterase: 'Classical' and 'non-classical' functions and pharmacology Current Opinion in Pharmacology. 5: 293-302. PMID 15907917 DOI: 10.1016/J.Coph.2005.01.014 |
0.544 |
|
| 2005 |
Premkumar L, Greenblatt HM, Bageshwar UK, Savchenko T, Gokhman I, Sussman JL, Zamir A. Three-dimensional structure of a halotolerant algal carbonic anhydrase predicts halotolerance of a mammalian homolog. Proceedings of the National Academy of Sciences of the United States of America. 102: 7493-8. PMID 15894606 DOI: 10.1073/Pnas.0502829102 |
0.322 |
|
| 2005 |
Premkumar L, Sawkar AR, Boldin-Adamsky S, Toker L, Silman I, Kelly JW, Futerman AH, Sussman JL. X-ray structure of human acid-beta-glucosidase covalently bound to conduritol-B-epoxide. Implications for Gaucher disease. The Journal of Biological Chemistry. 280: 23815-9. PMID 15817452 DOI: 10.1074/Jbc.M502799200 |
0.584 |
|
| 2005 |
Jaakola VP, Prilusky J, Sussman JL, Goldman A. G protein-coupled receptors show unusual patterns of intrinsic unfolding. Protein Engineering, Design & Selection : Peds. 18: 103-10. PMID 15790574 DOI: 10.1093/Protein/Gzi004 |
0.33 |
|
| 2005 |
Harel M, Hyatt JL, Brumshtein B, Morton CL, Yoon KJ, Wadkins RM, Silman I, Sussman JL, Potter PM. The crystal structure of the complex of the anticancer prodrug 7-ethyl-10-[4-(1-piperidino)-1-piperidino]-carbonyloxycamptothecin (CPT-11) with Torpedo californica acetylcholinesterase provides a molecular explanation for its cholinergic action. Molecular Pharmacology. 67: 1874-81. PMID 15772291 DOI: 10.1124/Mol.104.009944 |
0.591 |
|
| 2005 |
Niu C, Xu Y, Luo X, Duan W, Silman I, Sussman JL, Zhu W, Chen K, Shen J, Jiang H. Dynamic mechanism of E2020 binding to acetylcholinesterase: A steered molecular dynamics simulation Journal of Physical Chemistry B. 109: 23730-23738. DOI: 10.1021/jp0552877 |
0.418 |
|
| 2004 |
Greenblatt HM, Guillou C, Guénard D, Argaman A, Botti S, Badet B, Thal C, Silman I, Sussman JL. The complex of a bivalent derivative of galanthamine with torpedo acetylcholinesterase displays drastic deformation of the active-site gorge: implications for structure-based drug design. Journal of the American Chemical Society. 126: 15405-11. PMID 15563167 DOI: 10.1021/Ja0466154 |
0.617 |
|
| 2004 |
Dvir H, Harel M, Bon S, Liu WQ, Vidal M, Garbay C, Sussman JL, Massoulié J, Silman I. The synaptic acetylcholinesterase tetramer assembles around a polyproline II helix. The Embo Journal. 23: 4394-405. PMID 15526038 DOI: 10.1038/Sj.Emboj.7600425 |
0.561 |
|
| 2004 |
Hasin Y, Avidan N, Bercovich D, Korczyn A, Silman I, Beckmann JS, Sussman JL. A paradigm for single nucleotide polymorphism analysis: the case of the acetylcholinesterase gene. Human Mutation. 24: 408-16. PMID 15459952 DOI: 10.1002/Humu.20106 |
0.501 |
|
| 2004 |
Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RB, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes. Nature Structural & Molecular Biology. 11: 412-9. PMID 15098021 DOI: 10.1038/Nsmb767 |
0.551 |
|
| 2004 |
Bageshwar UK, Premkumar L, Gokhman I, Savchenko T, Sussman JL, Zamir A. Natural protein engineering: a uniquely salt-tolerant, but not halophilic, alpha-type carbonic anhydrase from algae proliferating in low- to hyper-saline environments. Protein Engineering, Design & Selection : Peds. 17: 191-200. PMID 15047915 DOI: 10.1093/Protein/Gzh022 |
0.305 |
|
| 2004 |
Futerman AH, Sussman JL, Horowitz M, Silman I, Zimran A. New directions in the treatment of Gaucher disease. Trends in Pharmacological Sciences. 25: 147-51. PMID 15019270 DOI: 10.1016/J.Tips.2004.01.004 |
0.506 |
|
| 2004 |
Pe'er I, Felder CE, Man O, Silman I, Sussman JL, Beckmann JS. Proteomic signatures: amino acid and oligopeptide compositions differentiate among phyla. Proteins. 54: 20-40. PMID 14705021 DOI: 10.1002/Prot.10559 |
0.478 |
|
| 2004 |
Colletier JP, Royant A, Specht A, Nachon F, Zaccai G, Goeldner M, Sussman JL, Silman I, Bourgeois D, Weik M. Kinetic crystallography on cholinesterases Acta Crystallographica Section a Foundations of Crystallography. 60: s122-s122. DOI: 10.1107/S0108767304097594 |
0.501 |
|
| 2004 |
Harel M, Aharoni A, Gaidukov L, Brumshtein B, Khersonsky O, Meged R, Dvir H, Ravelli RBG, McCarthy A, Toker L, Silman I, Sussman JL, Tawfik DS. Erratum: Corrigendum: Structure and evolution of the serum paraoxonase family of detoxifying and anti-atherosclerotic enzymes Nature Structural & Molecular Biology. 11: 1253-1253. DOI: 10.1038/Nsmb1204-1253A |
0.56 |
|
| 2004 |
Liu T, Zhu W, Gu J, Shen J, Luo X, Chen G, Puah CM, Silman I, Chen K, Sussman JL, Jiang H. Additivity of cation-π interactions: An ab initio computational study on π- Cation-π sandwich complexes Journal of Physical Chemistry A. 108: 9400-9405. DOI: 10.1021/Jp0476850 |
0.445 |
|
| 2003 |
Xu Y, Shen J, Luo X, Silman I, Sussman JL, Chen K, Jiang H. How does huperzine A enter and leave the binding gorge of acetylcholinesterase? Steered molecular dynamics simulations. Journal of the American Chemical Society. 125: 11340-9. PMID 16220957 DOI: 10.1021/Ja029775T |
0.544 |
|
| 2003 |
Fuchs S, Kasher R, Balass M, Scherf T, Harel M, Fridkin M, Sussman JL, Katchalski-Katzir E. The binding site of acetylcholine receptor: from synthetic peptides to solution and crystal structure. Annals of the New York Academy of Sciences. 998: 93-100. PMID 14592866 DOI: 10.1196/Annals.1254.011 |
0.307 |
|
| 2003 |
Zeev-Ben-Mordehai T, Rydberg EH, Solomon A, Toker L, Auld VJ, Silman I, Botti S, Sussman JL. The intracellular domain of the Drosophila cholinesterase-like neural adhesion protein, gliotactin, is natively unfolded. Proteins. 53: 758-67. PMID 14579366 DOI: 10.1002/Prot.10471 |
0.539 |
|
| 2003 |
Greenblatt HM, Dvir H, Silman I, Sussman JL. Acetylcholinesterase: a multifaceted target for structure-based drug design of anticholinesterase agents for the treatment of Alzheimer's disease. Journal of Molecular Neuroscience : Mn. 20: 369-83. PMID 14501022 DOI: 10.1385/Jmn:20:3:369 |
0.572 |
|
| 2003 |
Dvir H, Harel M, McCarthy AA, Toker L, Silman I, Futerman AH, Sussman JL. X-ray structure of human acid-beta-glucosidase, the defective enzyme in Gaucher disease. Embo Reports. 4: 704-9. PMID 12792654 DOI: 10.1038/Sj.Embor.Embor873 |
0.554 |
|
| 2003 |
Premkumar L, Greenblatt HM, Bageshwar UK, Savchenko T, Gokhman I, Zamir A, Sussman JL. Identification, cDNA cloning, expression, crystallization and preliminary X-ray analysis of an exceptionally halotolerant carbonic anhydrase from Dunaliella salina. Acta Crystallographica. Section D, Biological Crystallography. 59: 1084-6. PMID 12777782 DOI: 10.1107/S0907444903007066 |
0.333 |
|
| 2003 |
Premkumar L, Bageshwar UK, Gokhman I, Zamir A, Sussman JL. An unusual halotolerant alpha-type carbonic anhydrase from the alga Dunaliella salina functionally expressed in Escherichia coli. Protein Expression and Purification. 28: 151-7. PMID 12651119 DOI: 10.1016/S1046-5928(02)00683-6 |
0.358 |
|
| 2003 |
Katchalski-Katzir E, Kasher R, Balass M, Scherf T, Harel M, Fridkin M, Sussman JL, Fuchs S. Design and synthesis of peptides that bind alpha-bungarotoxin with high affinity and mimic the three-dimensional structure of the binding-site of acetylcholine receptor. Biophysical Chemistry. 100: 293-305. PMID 12646372 DOI: 10.1016/S0301-4622(02)00287-9 |
0.301 |
|
| 2003 |
Zeev-Ben-Mordehai T, Silman I, Sussman JL. Acetylcholinesterase in motion: Visualizing conformational changes in crystal structures by a morphing procedure Biopolymers. 68: 395-406. PMID 12601798 DOI: 10.1002/Bip.10287 |
0.569 |
|
| 2003 |
Wong DM, Greenblatt HM, Dvir H, Carlier PR, Han YF, Pang YP, Silman I, Sussman JL. Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity. Journal of the American Chemical Society. 125: 363-73. PMID 12517147 DOI: 10.1021/Ja021111W |
0.578 |
|
| 2002 |
Weik M, Bergès J, Raves ML, Gros P, McSweeney S, Silman I, Sussman JL, Houée-Levin C, Ravelli RB. Evidence for the formation of disulfide radicals in protein crystals upon X-ray irradiation. Journal of Synchrotron Radiation. 9: 342-6. PMID 12409620 DOI: 10.1107/S0909049502014589 |
0.551 |
|
| 2002 |
Felder CE, Harel M, Silman I, Sussman JL. Structure of a complex of the potent and specific inhibitor BW284C51 with Torpedo californica acetylcholinesterase. Acta Crystallographica. Section D, Biological Crystallography. 58: 1765-71. PMID 12351819 DOI: 10.1107/S0907444902011642 |
0.571 |
|
| 2002 |
Dvir H, Jiang HL, Wong DM, Harel M, Chetrit M, He XC, Jin GY, Yu GL, Tang XC, Silman I, Bai DL, Sussman JL. X-ray structures of Torpedo californica acetylcholinesterase complexed with (+)-huperzine A and (-)-huperzine B: structural evidence for an active site rearrangement. Biochemistry. 41: 10810-8. PMID 12196020 DOI: 10.1021/Bi020151+ |
0.592 |
|
| 2002 |
Koellner G, Steiner T, Millard CB, Silman I, Sussman JL. A neutral molecule in a cation-binding site: specific binding of a PEG-SH to acetylcholinesterase from Torpedo californica. Journal of Molecular Biology. 320: 721-5. PMID 12095250 DOI: 10.1016/S0022-2836(02)00475-8 |
0.587 |
|
| 2002 |
Bar-On P, Millard CB, Harel M, Dvir H, Enz A, Sussman JL, Silman I. Kinetic and structural studies on the interaction of cholinesterases with the anti-Alzheimer drug rivastigmine Biochemistry. 41: 3555-3564. PMID 11888271 DOI: 10.1021/Bi020016X |
0.571 |
|
| 2002 |
Dvir H, Wong DM, Harel M, Barril X, Orozco M, Luque FJ, Muñoz-Torrero D, Camps P, Rosenberry TL, Silman I, Sussman JL. 3D structure of Torpedo californica acetylcholinesterase complexed with huprine X at 2.1 A resolution: kinetic and molecular dynamic correlates. Biochemistry. 41: 2970-81. PMID 11863435 DOI: 10.1021/Bi011652I |
0.582 |
|
| 2002 |
LUO X, FENG C, TAN X, TAN C, ZHU D, SHEN J, HUANG X, LIU T, CHEN K, JIANG H, ZHU W, PUAH CM, DVIR H, HAREL M, SUSSMAN JL, et al. STRUCTURAL FEATURE OF AChE INHIBITOR HUPERZINE B IN NATURE AND IN THE BINDING SITE OF AChE: DENSITY FUNCTIONAL THEORY STUDY COMBINED WITH IR DETERMINATION Journal of Theoretical and Computational Chemistry. 1: 81-92. DOI: 10.1142/S0219633602000063 |
0.39 |
|
| 2002 |
Premkumar L, Greenblatt HM, Sussman JL, Bageshwar U, Savchenko T, Gokhman I, Zamir A. The first crystal structure of a halotolerant protein: carbonic anhydrase fromD. salinaat 1.86 Å resolution Acta Crystallographica Section a Foundations of Crystallography. 58: c307-c307. DOI: 10.1107/S010876730209726X |
0.345 |
|
| 2002 |
Harel M, Kasher R, Nicholas A, Guss JM, Smit AB, Brejc K, Sixma T, Katchalski-Katzir E, Sussman JL, Fuchs S. The structure of the binding site of acetylcholine receptor as visualized in the X-ray structure of a complex between α-bungarotoxin and a high affinity mimotope peptide Acta Crystallographica Section a Foundations of Crystallography. 58: c306-c306. DOI: 10.1107/S0108767302097234 |
0.337 |
|
| 2002 |
Weik M, Ravelli RBG, Silman I, Sussman JL, Gros P, Kroon J. Radiation damage to proteins studied by temperature-controlled cryo-crystallography Acta Crystallographica Section a Foundations of Crystallography. 58: c202-c202. DOI: 10.1107/S0108767302093078 |
0.482 |
|
| 2002 |
Dvir H, Wong DM, Harel M, Jiang HL, Rosenberry TL, Luque FJ, Camps P, Silman I, Sussman JL. 3D structures of Acetylcholinesterase complexes with potential drugs for the treatment of Alzheimer's disease Acta Crystallographica Section a Foundations of Crystallography. 58: c138-c138. DOI: 10.1107/S0108767302090542 |
0.525 |
|
| 2002 |
Jiang H, Shen J, Luo X, Liu H, Chen F, Tan X, Shen J, Chen K, Silman I, Sussman JL. Structure-based high throughput virtual screening for drug discovery Acta Crystallographica Section a Foundations of Crystallography. 58: c67-c67. DOI: 10.1107/S0108767302087706 |
0.509 |
|
| 2002 |
Liu T, Sussman JL, Gu J, Tan XJ, Zhu WL, Luo XM, Jiang HL, Ji RY, Chen KX, Silman I. The relationship between binding models of TMA with furan and imidazole and the molecular electrostatic potentials: DFT and MP2 computational studies Journal of Physical Chemistry A. 106: 157-164. DOI: 10.1021/Jp0113275 |
0.544 |
|
| 2001 |
Harel M, Kasher R, Nicolas A, Guss JM, Balass M, Fridkin M, Smit AB, Brejc K, Sixma TK, Katchalski-Katzir E, Sussman JL, Fuchs S. The binding site of acetylcholine receptor as visualized in the X-Ray structure of a complex between alpha-bungarotoxin and a mimotope peptide. Neuron. 32: 265-75. PMID 11683996 DOI: 10.1016/S0896-6273(01)00461-5 |
0.33 |
|
| 2001 |
Weik M, Ravelli RB, Silman I, Sussman JL, Gros P, Kroon J. Specific protein dynamics near the solvent glass transition assayed by radiation-induced structural changes. Protein Science : a Publication of the Protein Society. 10: 1953-61. PMID 11567086 DOI: 10.1110/Ps.09801 |
0.548 |
|
| 2001 |
Doucet-Personeni C, Bentley PD, Fletcher RJ, Kinkaid A, Kryger G, Pirard B, Taylor A, Taylor R, Taylor J, Viner R, Silman I, Sussman JL, Greenblatt HM, Lewis T. A structure-based design approach to the development of novel, reversible AChE inhibitors Journal of Medicinal Chemistry. 44: 3203-3215. PMID 11563919 DOI: 10.1021/Jm010826R |
0.572 |
|
| 2001 |
Nicolas A, Ferron F, Toker L, Sussman JL, Silman I. Histochemical method for characterization of enzyme crystals: application to crystals of Torpedo californica acetylcholinesterase. Acta Crystallographica. Section D, Biological Crystallography. 57: 1348-50. PMID 11526341 DOI: 10.1107/S0907444901010411 |
0.549 |
|
| 2001 |
Weik M, Kryger G, Schreurs AM, Bouma B, Silman I, Sussman JL, Gros P, Kroon J. Solvent behaviour in flash-cooled protein crystals at cryogenic temperatures. Acta Crystallographica. Section D, Biological Crystallography. 57: 566-73. PMID 11264586 DOI: 10.1107/S0907444901001196 |
0.525 |
|
| 2001 |
Liu T, Gu J, Tan XJ, Zhu WL, Luo XM, Jiang HL, Ji RY, Chen KX, Silman I, Sussman JL. Theoretical insight into the interactions of TMA-benzene and TMA-pyrrole with B3LYP Density-Functional Theory (DFT) and ab initio second order Møller-Plesset perturbation theory (MP2) calculations Journal of Physical Chemistry A. 105: 5431-5437. DOI: 10.1021/Jp003098C |
0.519 |
|
| 2001 |
Liu T, Gu J, Tan X, Zhu W, Luo X, Jiang H, Ji R, Chen K, Silman I, Sussman JL. Theoretical Insight into the Interactions of TMA-Benzene and TMA-Pyrrole with B3LYP Density-Functional Theory (DFT) and ab Initio Second Order Møller−Plesset Perturbation Theory (MP2) Calculations The Journal of Physical Chemistry A. 105: 5431-5437. DOI: 10.1021/JP003098C |
0.397 |
|
| 2001 |
Felder C, Jiang HL, Zhu WL, Chen KX, Silman I, Bottijt SA, Sussman JL. Quantum/classical mechanical comparison of cation-π interactions between tetramethylammonium and benzene Journal of Physical Chemistry A. 105: 1326-1333. DOI: 10.1021/Jp002933N |
0.502 |
|
| 2001 |
Felder C, Jiang H, Zhu W, Chen K, Silman I, Botti SA, Sussman JL. Quantum/Classical Mechanical Comparison of Cation−π Interactions between Tetramethylammonium and Benzene The Journal of Physical Chemistry A. 105: 1326-1333. DOI: 10.1021/JP002933N |
0.391 |
|
| 2001 |
Jian Tan X, Liang Zhu W, Cui M, Min Luo X, De Gu J, Silman I, Sussman JL, Liang Jiang H, Yun Ji R, Xian Chen K. Noncovalent interaction or chemical bonding between alkaline earth cations and benzene? a quantum chemistry study using MP2 and density-functional theory methods Chemical Physics Letters. 349: 113-122. DOI: 10.1016/S0009-2614(01)01176-9 |
0.503 |
|
| 2000 |
Kryger G, Harel M, Giles K, Toker L, Velan B, Lazar A, Kronman C, Barak D, Ariel N, Shafferman A, Silman I, Sussman JL. Structures of recombinant native and E202Q mutant human acetylcholinesterase complexed with the snake-venom toxin fasciculin-II Acta Crystallographica Section D: Biological Crystallography. 56: 1385-1394. PMID 11053835 DOI: 10.1107/S0907444900010659 |
0.595 |
|
| 2000 |
Lin D, Manning NO, Jiang J, Abola EE, Stampf D, Prilusky J, Sussman JL. AutoDep: A web-based system for deposition and validation of macromolecular structural Acta Crystallographica Section D: Biological Crystallography. 56: 828-841. PMID 10930830 DOI: 10.1107/S0907444900005655 |
0.556 |
|
| 2000 |
Harel M, Kryger G, Rosenberry TL, Mallender WD, Lewis T, Fletcher RJ, Guss JM, Silman I, Sussman JL. Three-dimensional structures of Drosophila melanogaster acetylcholinesterase and of its complexes with two potent inhibitors Protein Science. 9: 1063-1072. PMID 10892800 DOI: 10.1110/Ps.9.6.1063 |
0.615 |
|
| 2000 |
Koellner G, Kryger G, Millard CB, Silman I, Sussman JL, Steiner T. Active-site gorge and buried water molecules in crystal structures of acetylcholinesterase from Torpedo californica Journal of Molecular Biology. 296: 713-735. PMID 10669619 DOI: 10.1006/Jmbi.1999.3468 |
0.55 |
|
| 2000 |
Weik M, Ravelli RBG, Kryger G, McSweeney S, Raves ML, Harel M, Gros P, Silman I, Kroon J, Sussman JL. Specific chemical and structural damage to proteins produced by synchrotron radiation Proceedings of the National Academy of Sciences of the United States of America. 97: 623-628. PMID 10639129 DOI: 10.1073/Pnas.97.2.623 |
0.564 |
|
| 2000 |
Weik M, Gros P, Kroon J, Ursby T, Bourgeois D, Ravelli R, McSweeney S, Peng L, Specht A, Goeldner M, Kryger G, Silman I, Sussman J. Temperature-controlled crystallographic experiments on acetylcholinesterase Acta Crystallographica Section a Foundations of Crystallography. 56: s255-s255. DOI: 10.1107/S0108767300025472 |
0.455 |
|
| 2000 |
Zhu WL, Tan XJ, Puah CM, Gu JD, Jiang HL, Chen KX, Felder CE, Silman I, Sussman JL. How does ammonium interact with aromatic groups? A density functional theory (DFT/B3LYP) investigation Journal of Physical Chemistry A. 104: 9573-9580. DOI: 10.1021/Jp001306V |
0.519 |
|
| 2000 |
Greenblatt HM, Silman I, Sussman JL. Structural studies on vertebrate and invertebrate acetylcholinesterases and their complexes with functional ligands Drug Development Research. 50: 573-583. DOI: 10.1002/1098-2299(200007/08)50:3/4<573::Aid-Ddr41>3.0.Co;2-7 |
0.597 |
|
| 2000 |
Greenblatt HM, Silman I, Sussman JL. Structural studies on vertebrate and invertebrate acetylcholinesterases and their complexes with functional ligands Drug Development Research. 50: 573-583. DOI: 10.1002/1098-2299(200007/08)50:3/4<573::AID-DDR41>3.0.CO;2-7 |
0.485 |
|
| 1999 |
Sussman JL, Abola EE, Lin D, Jiang J, Manning NO, Prilusky J. The protein data bank: Bridging the gap between the sequence and 3D structure world Genetica. 106: 149-158. PMID 10710721 DOI: 10.1023/A:1003753517358 |
0.525 |
|
| 1999 |
Greenblatt HM, Kryger G, Lewis T, Silman I, Sussman JL. Structure of acetylcholinesterase complexed with (-)-galanthamine at 2.3 Å resolution Febs Letters. 463: 321-326. PMID 10606746 DOI: 10.1016/S0014-5793(99)01637-3 |
0.581 |
|
| 1999 |
Botti SA, Felder CE, Lifson S, Sussman JL, Silman I. A modular treatment of molecular traffic through the active site of cholinesterase. Biophysical Journal. 77: 2430-50. PMID 10545346 DOI: 10.1016/S0006-3495(99)77080-3 |
0.54 |
|
| 1999 |
Silman I, Millard CB, Ordentlich A, Greenblatt HM, Harel M, Barak D, Shafferman A, Sussman JL. A preliminary comparison of structural models for catalytic intermediates of acetylcholinesterase Chemico-Biological Interactions. 119: 43-52. PMID 10421437 DOI: 10.1016/S0009-2797(99)00012-5 |
0.623 |
|
| 1999 |
Kryger G, Silman I, Sussman JL. Structure of acetylcholinesterase complexed with E2020 (Ariceptρ): Implications for the design of new anti-Alzheimer drugs Structure. 7: 297-307. PMID 10368299 DOI: 10.1016/S0969-2126(99)80040-9 |
0.549 |
|
| 1999 |
Millard CB, Kryger G, Ordentlich A, Greenblatt HM, Harel M, Raves ML, Segall Y, Barak D, Shafferman A, Silman I, Sussman JL. Crystal structures of aged phosphonylated acetylcholinesterase: Nerve agent reaction products at the atomic level Biochemistry. 38: 7032-7039. PMID 10353814 DOI: 10.1021/Bi982678L |
0.592 |
|
| 1999 |
Morel N, Bon S, Greenblatt HM, Van Belle D, Wodak SJ, Sussman JL, Massoulié J, Silman I. Effect of mutations within the peripheral anionic site on the stability of acetylcholinesterase. Molecular Pharmacology. 55: 982-92. PMID 10347238 DOI: 10.1124/mol.55.6.982 |
0.658 |
|
| 1999 |
Jiang J, Abola E, Sussman JL. Deposition of structure factors at the Protein Data Bank [2] Acta Crystallographica Section D: Biological Crystallography. 55: 4. PMID 10089388 DOI: 10.1107/S0907444998016631 |
0.374 |
|
| 1999 |
Millard CB, Koellner G, Ordentlich A, Shafferman A, Silman I, Sussman JL. Reaction products of acetylcholinesterase and VX reveal a mobile histidine in the catalytic triad [7] Journal of the American Chemical Society. 121: 9883-9884. DOI: 10.1021/Ja992704I |
0.569 |
|
| 1999 |
Sussman JL, Abola EE, Lin D, Jiang J, Manning NO, Prilusky J. The protein data bank Genetica. 106: 441-441. DOI: 10.1007/978-1-4899-0375-4_26 |
0.557 |
|
| 1998 |
Ravelli RBG, Raves ML, Ren Z, Bourgeois D, Roth M, Kroon J, Silman I, Sussman JL. Static Laue diffraction studies on acetylcholinesterase Acta Crystallographica Section D: Biological Crystallography. 54: 1359-1366. PMID 10089512 DOI: 10.1107/S0907444998005277 |
0.591 |
|
| 1998 |
Sussman JL, Lin D, Jiang J, Manning NO, Prilusky J, Ritter O, Abola EE. Protein Data Bank (PDB): Database of three-dimensional structural information of biological macromolecules Acta Crystallographica Section D: Biological Crystallography. 54: 1078-1084. PMID 10089483 DOI: 10.1107/S0907444998009378 |
0.584 |
|
| 1998 |
Kryger G, Silman I, Sussman JL. Three-dimensional structure of a complex of E2020 with acetylcholinesterase from Torpedo californica Journal of Physiology Paris. 92: 191-194. PMID 9789806 DOI: 10.1016/S0928-4257(98)80008-9 |
0.591 |
|
| 1998 |
Botti SA, Felder CE, Sussman JL, Silman I. Electrotactins: A class of adhesion proteins with conserved electrostatic and structural motifs Protein Engineering. 11: 415-420. PMID 9725619 DOI: 10.1093/Protein/11.6.415 |
0.564 |
|
| 1998 |
Botti S, Felder C, Sussman J, Silman I. Electrostatic homology modelling of a set of ChE-like neural adhesion proteins identifies a shared ‘annular’ motif with ChEs. Structural implications for a cell-recognition role of ChEs Journal of Physiology-Paris. 92: 414-416. DOI: 10.1016/S0928-4257(99)80027-8 |
0.543 |
|
| 1998 |
Bar-On P, Harel M, Millard C, Enz A, Sussman J, Silman I. Kinetic and structural studies on the interaction of the anti-Alzheimer drug, ENA-713, with Torpedo californica acetylcholinesterase Journal of Physiology-Paris. 92: 406-407. DOI: 10.1016/S0928-4257(99)80019-9 |
0.534 |
|
| 1997 |
Felder CE, Botti SA, Lifson S, Silman I, Sussman JL. External and internal electrostatic potentials of cholinesterase models. Journal of Molecular Graphics & Modelling. 15: 318-27, 335-7. PMID 9640563 DOI: 10.1016/S1093-3263(98)00005-9 |
0.575 |
|
| 1997 |
Abola EE, Sussman JL, Prilusky J, Manning NO. Protein data bank archives of three-dimensional macromolecular structures Methods in Enzymology. 277: 556-571. PMID 9379928 DOI: 10.1016/S0076-6879(97)77031-9 |
0.372 |
|
| 1997 |
Raves ML, Harel M, Pang YP, Silman I, Kozikowski AP, Sussman JL. Structure of acetylcholinesterase complexed with the nootropic alkaloid, (-)-huperzine A Nature Structural Biology. 4: 57-63. PMID 8989325 DOI: 10.1038/Nsb0197-57 |
0.621 |
|
| 1997 |
Giles K, Silman I, Sussman J. Human acetylcholinesterase II: In vivo expression and tissue distribution via est analyses Neuroscience Letters. 237: S19-S20. DOI: 10.1016/S0304-3940(97)90079-3 |
0.457 |
|
| 1997 |
Giles K, Sussman J, Silman I. Human acetylcholinesterase I: In vitro assembly of subunits Neuroscience Letters. 237: S19. DOI: 10.1016/S0304-3940(97)90078-1 |
0.474 |
|
| 1997 |
Botti S, Felder C, Lifson S, Silman I, Sussman J. An integrated model for the molecular traffic through the active site of cholinesterases Neuroscience Letters. 237: S11. DOI: 10.1016/S0304-3940(97)90044-6 |
0.533 |
|
| 1997 |
Botti S, Felder C, Sussman J, Silman I. The conjuction of a conserved electrostatic motif and a common cholinesterase fold defines a class of adhesion proteins Neuroscience Letters. 237: S11. DOI: 10.1016/S0304-3940(97)90043-4 |
0.576 |
|
| 1997 |
Bar-On P, Millard C, Enz A, Sussman J, Silman I. Evidence that the anti-Alzheimer drug, ENA-713, inhibits acetylcholinesterase by more than one mechanism Neuroscience Letters. 237: S6. DOI: 10.1016/S0304-3940(97)90026-4 |
0.474 |
|
| 1996 |
Abola EE, Manning NO, Prilusky J, Stampf DR, Sussman JL. The Protein Data Bank: Current Status and Future Challenges. Journal of Research of the National Institute of Standards and Technology. 101: 231-241. PMID 27805161 DOI: 10.6028/Jres.101.025 |
0.342 |
|
| 1996 |
Marchot P, Ravelli RBG, Raves ML, Bourne Y, Vellom DC, Kanter J, Camp S, Sussman JL, Taylor P. Soluble monomeric acetylcholinesterase from mouse: Expression, purification, and crystallization in complex with fasciculin Protein Science. 5: 672-679. PMID 8845756 DOI: 10.1002/Pro.5560050411 |
0.354 |
|
| 1996 |
Baker EN, Blundell TL, Dodson E, Dodson G, Gilliland GL, Sussman JL, Vijayan M. Diffraction data deposition Structure (London, England : 1993). 4: 217. PMID 8805528 DOI: 10.1016/S0969-2126(96)00024-X |
0.35 |
|
| 1996 |
Porschke D, Créminon C, Cousin X, Bon C, Sussman J, Silman I. Electrooptical measurements demonstrate a large permanent dipole moment associated with acetylcholinesterase. Biophysical Journal. 70: 1603-8. PMID 8785319 DOI: 10.1016/S0006-3495(96)79759-X |
0.54 |
|
| 1996 |
Peng L, Silman I, Sussman J, Goeldner M. Biochemical evaluation of photolabile precursors of choline and of carbamylcholine for potential time-resolved crystallographic studies on cholinesterases. Biochemistry. 35: 10854-61. PMID 8718877 DOI: 10.1021/Bi9529014 |
0.56 |
|
| 1996 |
Wlodek ST, Antosiewicz J, McCammon JA, Straatsma TP, Gilson MK, Briggs JM, Humblet C, Sussman JL. Binding of tacrine and 6-chlorotacrine by acetylcholinesterase. Biopolymers. 38: 109-17. PMID 8679940 DOI: 10.1002/(SICI)1097-0282(199601)38:1<109::AID-BIP9>3.0.CO;2-# |
0.309 |
|
| 1996 |
Faerman C, Ripoll D, Bon S, Le Feuvre Y, Morel N, Massoulié J, Sussman JL, Silman I. Site-directed mutants designed to test back-door hypotheses of acetylcholinesterase function. Febs Letters. 386: 65-71. PMID 8635606 DOI: 10.1016/0014-5793(96)00374-2 |
0.574 |
|
| 1996 |
Frolow F, Harel M, Sussman JL, Mevarech M, Shoham M. Insights into protein adaptation to a saturated salt environment from the crystal structure of a halophilic 2Fe-2S ferredoxin. Nature Structural Biology. 3: 452-8. PMID 8612076 DOI: 10.1038/Nsb0596-452 |
0.363 |
|
| 1996 |
Baker EN, Bluntell TL, Vijayan M, Dodson E, Dodson G, Gilliland GL, Sussman JL. Publication of macromolecular crystal structures Febs Letters. 380: 301. PMID 8601446 DOI: 10.1016/0014-5793(96)83096-1 |
0.345 |
|
| 1996 |
Raves ML, Ravelli RBG, Kroon J, Roth M, Bourgeois D, Peng L, Goeldner M, Silman I, Sussman JL. Laue studies on acetylcholinesterase Acta Crystallographica Section a Foundations of Crystallography. 52: C50-C50. DOI: 10.1107/S0108767396097048 |
0.488 |
|
| 1996 |
Harel M, Kleywegt GJ, Ravelli RBG, Silman I, Sussman JL. Structure and interactions of a complex of snake venom toxin and acetylcholinesterase Acta Crystallographica Section a Foundations of Crystallography. 52: C121-C121. DOI: 10.1107/S0108767396094329 |
0.556 |
|
| 1996 |
Abola EE, Prilusky J, Manning NO, Sussman JL. 3DBase – a macromolecular structure database Acta Crystallographica Section a Foundations of Crystallography. 52: C586-C586. DOI: 10.1107/S0108767396076180 |
0.342 |
|
| 1996 |
Harel M, Quinn DM, Nair HK, Silman I, Sussman JL. The X-ray structure of a transition state analog complex reveals the molecular origins of the catalytic power and substrate specificity of acetylcholinesterase Journal of the American Chemical Society. 118: 2340-2346. DOI: 10.1021/Ja952232H |
0.569 |
|
| 1995 |
Sussman JL, Berman HM. New guidelines for deposition of nucleic acid structures Structure. 3: 1426. PMID 8747467 DOI: 10.1016/S0969-2126(01)00278-7 |
0.326 |
|
| 1995 |
Harel M, Kleywegt GJ, Ravelli RB, Silman I, Sussman JL. Crystal structure of an acetylcholinesterase-fasciculin complex: interaction of a three-fingered toxin from snake venom with its target. Structure (London, England : 1993). 3: 1355-66. PMID 8747462 DOI: 10.1016/S0969-2126(01)00273-8 |
0.578 |
|
| 1995 |
Stampf DR, Felder CE, Sussman JL. PDBbrowse--a graphics interface to the Brookhaven Protein Data Bank Nature. 374: 572-574. PMID 7700388 DOI: 10.1038/374572A0 |
0.33 |
|
| 1995 |
Alon RN, Mirny L, Sussman JL, Gutnick DL. Detection of α/β-hydrolase fold in the cell surface esterases of Acinetobacter species using an analysis of 3D profiles Febs Letters. 371: 231-235. PMID 7556598 DOI: 10.1016/0014-5793(95)00861-3 |
0.332 |
|
| 1995 |
Dym O, Mevarech M, Sussman JL. Structural features that stabilize halophilic malate dehydrogenase from an archaebacterium Science. 267: 1344-1346. DOI: 10.1126/Science.267.5202.1344 |
0.346 |
|
| 1994 |
Gilson MK, Straatsma TP, McCammon JA, Ripoll DR, Faerman CH, Axelsen PH, Silman I, Sussman JL. Open 'back door' in a molecular dynamics simulation of acetylcholinesterase Science. 263: 1276-1278. PMID 8122110 DOI: 10.1126/science.8122110 |
0.501 |
|
| 1994 |
Axelsen PH, Harel M, Silman I, Sussman JL. Structure and dynamics of the active site gorge of acetylcholinesterase: Synergistic use of molecular dynamics simulation and X-ray crystallography Protein Science. 3: 188-197. PMID 8003956 DOI: 10.1002/Pro.5560030204 |
0.594 |
|
| 1994 |
Kreimer DI, Dolginova EA, Raves M, Sussman JL, Silman I, Weiner L. A metastable state of Torpedo californica acetylcholinesterase generated by modification with organomercurials. Biochemistry. 33: 14407-18. PMID 7981200 DOI: 10.1021/Bi00252A006 |
0.527 |
|
| 1994 |
Silman I, Harel M, Axelsen P, Raves M, Sussman JL. Three-dimensional structures of acetylcholinesterase and of its complexes with anticholinesterase agents Biochemical Society Transactions. 22: 745-749. PMID 7821677 DOI: 10.1042/Bst0220745 |
0.544 |
|
| 1993 |
Ripoll DR, Faerman CH, Axelsen PH, Silman I, Sussman JL. An electrostatic mechanism for substrate guidance down the aromatic gorge of acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America. 90: 5128-32. PMID 8506359 DOI: 10.1073/Pnas.90.11.5128 |
0.57 |
|
| 1993 |
Livnah O, Bayer EA, Wilchek M, Sussman JL. Three-dimensional structures of avidin and the avidin-biotin complex Proceedings of the National Academy of Sciences of the United States of America. 90: 5076-5080. PMID 8506353 DOI: 10.1073/Pnas.90.11.5076 |
0.397 |
|
| 1993 |
Wagner UG, Pattridge KA, Ludwig ML, Stallings WC, Werber MM, Oefner C, Frolow F, Sussman JL. Comparison of the crystal structures of genetically engineered human manganese superoxide dismutase and manganese superoxide dismutase from Thermus thermophilus: differences in dimer-dimer interaction. Protein Science : a Publication of the Protein Society. 2: 814-25. PMID 8495200 DOI: 10.1002/Pro.5560020511 |
0.397 |
|
| 1993 |
Cygler M, Schrag JD, Sussman JL, Harel M, Silman I, Gentry MK, Doctor BP. Relationship between sequence conservation and three-dimensional structure in a large family of esterases, lipases, and related proteins. Protein Science : a Publication of the Protein Society. 2: 366-82. PMID 8453375 DOI: 10.1002/Pro.5560020309 |
0.595 |
|
| 1993 |
Harel M, Schalk I, Ehret-Sabatier L, Bouet F, Goeldner M, Hirth C, Axelsen PH, Silman I, Sussman JL. Quaternary ligand binding to aromatic residues in the active-site gorge of acetylcholinesterase. Proceedings of the National Academy of Sciences of the United States of America. 90: 9031-5. PMID 8415649 DOI: 10.1073/Pnas.90.19.9031 |
0.568 |
|
| 1993 |
Livnah O, Bayer EA, Wilchek M, Sussman JL. The structure of the complex between avidin and the dye, 2-(4'-hydroxyazobenzene) benzoic acid (HABA) Febs Letters. 328: 165-168. PMID 8344421 DOI: 10.1016/0014-5793(93)80986-5 |
0.383 |
|
| 1993 |
Sussman JL, Harel M, Silman I. Three-dimensional structure of acetylcholinesterase and of its complexes with anticholinesterase drugs Chemico-Biological Interactions. 87: 187-197. PMID 8343975 DOI: 10.1016/0009-2797(93)90042-W |
0.625 |
|
| 1993 |
Massoulié J, Sussman J, Bon S, Silman I. Structure and functions of acetylcholinesterase and butyrylcholinesterase. Progress in Brain Research. 98: 139-46. PMID 8248501 DOI: 10.1016/S0079-6123(08)62391-2 |
0.583 |
|
| 1993 |
Unger R, Sussman JL. The importance of short structural motifs in protein structure analysis Journal of Computer-Aided Molecular Design. 7: 457-472. PMID 8229095 DOI: 10.1007/Bf02337561 |
0.394 |
|
| 1993 |
Harel M, Silman I, Sussman JL. Conversion of the three-dimensional structure of acetylcholinesterase to butyrylcholine-sterase: modeling and mutagenesis Acta Crystallographica Section a Foundations of Crystallography. 49: c99-c100. DOI: 10.1107/S0108767378097160 |
0.55 |
|
| 1993 |
Harel M, Silman I, Sussman JL. Quaternary ligand binding sites of acetylcholinesterase as revealed by X-ray crystallography Acta Crystallographica Section a Foundations of Crystallography. 49: c157-c157. DOI: 10.1107/S0108767378095501 |
0.519 |
|
| 1993 |
Joshua-Tor L, Sussman JL. The coming of age of DMA crystallography Current Opinion in Structural Biology. 3: 323-335. DOI: 10.1016/S0959-440X(05)80102-2 |
0.617 |
|
| 1992 |
Joshua-Tor L, Frolow F, Appella E, Hope H, Rabinovich D, Sussman JL. Three-dimensional structures of bulge-containing DNA fragments. Journal of Molecular Biology. 225: 397-431. PMID 1593627 DOI: 10.1016/0022-2836(92)90929-E |
0.652 |
|
| 1992 |
Berman HM, Sussman JL, Joshua-Tor L, Revich GG, Ripley LS. A structural model for sequence-specific proflavin-dna interactions during in vitro frameshift mutagenesis Journal of Biomolecular Structure and Dynamics. 10: 317-331. PMID 1466812 DOI: 10.1080/07391102.1992.10508650 |
0.631 |
|
| 1992 |
Harel M, Sussman JL, Krejci E, Bon S, Chanal P, Massoulié J, Silman I. Conversion of acetylcholinesterase to butyrylcholinesterase: modeling and mutagenesis. Proceedings of the National Academy of Sciences of the United States of America. 89: 10827-31. PMID 1438284 DOI: 10.1073/Pnas.89.22.10827 |
0.583 |
|
| 1992 |
Duval N, Bon S, Silman I, Sussman J, Massoulié J. Site-directed mutagenesis of active-site-related residues in Torpedo acetylcholinesterase. Presence of a glutamic acid in the catalytic triad. Febs Letters. 309: 421-3. PMID 1355448 DOI: 10.1016/0014-5793(92)80821-W |
0.576 |
|
| 1992 |
Sussman JL, Silman I. Acetylcholinesterase: structure and use as a model for specific cation—protein interactions Current Opinion in Structural Biology. 2: 721-729. DOI: 10.1016/0960-9822(92)90176-B |
0.544 |
|
| 1992 |
Sussman JL, Silman I. Acetylcholinesterase: Structure and use as a model for specific cation-protein interactions Current Biology. 2: 612. DOI: 10.1016/0960-9822(92)90176-B |
0.513 |
|
| 1991 |
Harel M, Su CT, Frolow F, Silman I, Sussman JL. Gamma-chymotrypsin is a complex of alpha-chymotrypsin with its own autolysis products. Biochemistry. 30: 5217-25. PMID 2036388 DOI: 10.1021/Bi00235A015 |
0.588 |
|
| 1991 |
Harel M, Su CT, Frolow F, Ashani Y, Silman I, Sussman JL. Refined crystal structures of "aged" and "non-aged" organophosphoryl conjugates of gamma-chymotrypsin. Journal of Molecular Biology. 221: 909-18. PMID 1942036 DOI: 10.1016/0022-2836(91)80183-U |
0.517 |
|
| 1991 |
Sussman JL, Harel M, Frolow F, Oefner C, Goldman A, Toker L, Silman I. Atomic structure of acetylcholinesterase from Torpedo californica: a prototypic acetylcholine-binding protein. Science (New York, N.Y.). 253: 872-9. PMID 1678899 DOI: 10.1126/Science.1678899 |
0.606 |
|
| 1990 |
Livnah O, Sussman JL. Crystal forms of avidin. Methods in Enzymology. 184: 90-3. PMID 2388599 DOI: 10.1016/0076-6879(90)84263-G |
0.325 |
|
| 1990 |
Unger R, Harel D, Wherland S, Sussman JL. Analysis of dihedral angles distribution: The doublets distribution determines polypeptides conformations Biopolymers. 30: 499-508. DOI: 10.1002/Bip.360300503 |
0.309 |
|
| 1989 |
Unger R, Harel D, Wherland S, Sussman JL. A 3D building blocks approach to analyzing and predicting structure of proteins. Proteins. 5: 355-73. PMID 2798411 DOI: 10.1002/Prot.340050410 |
0.367 |
|
| 1988 |
Abad-Zapatero C, Griffith JP, Sussman JL, Rossmann MG. Refined crystal structure of dogfish M4 apo-lactate dehydrogenase. Journal of Molecular Biology. 198: 445-67. PMID 3430615 DOI: 10.1016/0022-2836(87)90293-2 |
0.4 |
|
| 1988 |
Miller M, Harrison RW, Wlodawer A, Appella E, Sussman JL. Crystal structure of 15-mer DNA duplex containing unpaired bases. Nature. 334: 85-6. PMID 3386752 DOI: 10.1038/334085A0 |
0.36 |
|
| 1988 |
Joshua-Tor L, Rabinovich D, Hope H, Frolow F, Appella E, Sussman JL. The three-dimensional structure of a DNA duplex containing looped-out bases. Nature. 334: 82-4. PMID 3386751 DOI: 10.1038/334082A0 |
0.624 |
|
| 1988 |
Sussman JL, Harel M, Frolow F, Varon L, Toker L, Futerman AH, Silman I. Purification and crystallization of a dimeric form of acetylcholinesterase from Torpedo californica subsequent to solubilization with phosphatidylinositol-specific phospholipase C. Journal of Molecular Biology. 203: 821-3. PMID 2850366 DOI: 10.1016/0022-2836(88)90213-6 |
0.535 |
|
| 1987 |
Miller M, Wlodawer A, Appella E, Sussman JL. Crystallization of a DNA duplex 15-mer containing unpaired bases: d(CGCGAAATTTACGCG). Journal of Molecular Biology. 195: 967-8. PMID 3656440 DOI: 10.1016/0022-2836(87)90503-1 |
0.312 |
|
| 1986 |
Roy S, Weinstein S, Borah B, Nickol J, Appella E, Sussman JL, Miller M, Shindo H, Cohen JS. Mechanism of oligonucleotide loop formation in solution. Biochemistry. 25: 7417-23. PMID 3801420 DOI: 10.1021/Bi00371A025 |
0.302 |
|
| 1986 |
Sussman JL. Constrained-restrained least-squares (CORELS) refinement of proteins and nucleic acids. Methods in Enzymology. 115: 271-303. PMID 2417093 DOI: 10.1016/0076-6879(85)15022-6 |
0.322 |
|
| 1986 |
Werber MM, Sussman J, Eisenberg H. Molecular basis for the special properties of proteins and enzymes fromHalobacterium marismortui Fems Microbiology Letters. 39: 129-135. DOI: 10.1111/J.1574-6968.1986.Tb01853.X |
0.361 |
|
| 1984 |
Sussman JL, Shoham M, Harel M, Yonath A. The three-dimensional structure of a 'salt-loving' ferredoxin from halobacterium of the Dead Sea Acta Crystallographica Section a Foundations of Crystallography. 40: C40-C40. DOI: 10.1107/S0108767384098585 |
0.335 |
|
| 1981 |
Holbrook SR, Sussman JL, Kim SH. Absence of correlation between base-pair sequence and RNA conformation. Science (New York, N.Y.). 212: 1275-7. PMID 6165084 DOI: 10.1126/Science.6165084 |
0.532 |
|
| 1979 |
Shoham M, Yonath A, Sussman JL, Moult J, Traub W, Kalb AJ. Crystal structure of demetallized concanavalin A: the metal-binding region. Journal of Molecular Biology. 131: 137-55. PMID 490645 DOI: 10.1016/0022-2836(79)90070-6 |
0.38 |
|
| 1979 |
Schevitz RW, Podjarny AD, Krishnamachari N, Hughes JJ, Sigler PB, Sussman JL. Crystal structure of a eukaryotic initiator tRNA. Nature. 278: 188-90. PMID 368656 DOI: 10.1038/278188A0 |
0.393 |
|
| 1978 |
Shoham M, Sussman JL, Yonath A, Moult J, Traub W, Kalb(Gilboa) AJ. The effect of binding of metal ions on the three-dimensional structure of demetallized concanavalin A. Febs Letters. 95: 54-6. PMID 720606 DOI: 10.1016/0014-5793(78)80050-7 |
0.318 |
|
| 1978 |
Holbrook SR, Sussman JL, Warrant RW, Kim SH. Crystal structure of yeast phenylalanine transfer RNA. II. Structural features and functional implications. Journal of Molecular Biology. 123: 631-60. PMID 357743 DOI: 10.1016/0022-2836(78)90210-3 |
0.6 |
|
| 1978 |
Sussman JL, Holbrook SR, Warrant RW, Church GM, Kim SH. Crystal structure of yeast phenylalanine transfer RNA. I. Crystallographic refinement. Journal of Molecular Biology. 123: 607-30. PMID 357742 DOI: 10.1016/0022-2836(78)90209-7 |
0.367 |
|
| 1977 |
Holbrook SR, Sussman JL, Warrant RW, Church GM, Kim SH. RNA-ligant interactions. (I) Magnesium binding sites in yeast tRNAPhe. Nucleic Acids Research. 4: 2811-20. PMID 333395 DOI: 10.1093/Nar/4.8.2811 |
0.55 |
|
| 1977 |
Robillard GT, Tarr CE, Vosman F, Sussman JL. An NMR approach to tRNA tertiary structure in solution Biophysical Chemistry. 6: 291-298. PMID 328065 DOI: 10.1016/0301-4622(77)85010-2 |
0.363 |
|
| 1977 |
Church GM, Sussman JL, Kim SH. Secondary structural complementarity between DNA and proteins. Proceedings of the National Academy of Sciences of the United States of America. 74: 1458-62. PMID 266187 DOI: 10.1073/Pnas.74.4.1458 |
0.528 |
|
| 1977 |
Sussman JL, Holbrook SR, Church GM, Kim S. A structure-factor least-squares refinement procedure for macromolecular structures using constrainedandrestrained parameters Acta Crystallographica Section A. 33: 800-804. DOI: 10.1107/S0567739477001958 |
0.318 |
|
| 1976 |
Sussman JL, Kim SH. Idealized atomic coordinates of yeast phenylalanine transfer RNA. Biochemical and Biophysical Research Communications. 68: 89-96. PMID 1108880 DOI: 10.1016/0006-291X(76)90014-0 |
0.536 |
|
| 1976 |
Sussman JL, Kim S. Three-dimensional structure of a transfer rna in two crystal forms. Science (New York, N.Y.). 192: 853-8. PMID 775636 DOI: 10.1126/Science.775636 |
0.553 |
|
| 1976 |
Kim SH, Sussman JL. pi turn is a conformational pattern in RNA loops and bends. Nature. 260: 645-6. PMID 772447 DOI: 10.1038/260645A0 |
0.495 |
|
| 1975 |
Quigley GJ, Wang AH, Seeman NC, Suddath FL, Rich A, Sussman JL, Kim SH. Hydrogen bonding in yeast phenylalanine transfer RNA. Proceedings of the National Academy of Sciences of the United States of America. 72: 4866-70. PMID 1108007 DOI: 10.1073/Pnas.72.12.4866 |
0.471 |
|
| 1974 |
Kim SH, Sussman JL, Suddath FL, Quigley GJ, McPherson A, Wang AH, Seeman NC, RICH A. The general structure of transfer RNA molecules. Proceedings of the National Academy of Sciences of the United States of America. 71: 4970-4. PMID 4612535 DOI: 10.1073/Pnas.71.12.4970 |
0.547 |
|
| 1974 |
Kim SH, Suddath FL, Quigley GJ, McPherson A, Sussman JL, Wang AH, Seeman NC, Rich A. Three-dimensional tertiary structure of yeast phenylalanine transfer RNA. Science (New York, N.Y.). 185: 435-40. PMID 4601792 DOI: 10.1126/Science.185.4149.435 |
0.53 |
|
| 1973 |
Sussman JL, Wodak SJ. The crystal structure of fulvine: a pyrrolizidine alkaloid Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 29: 2918-2926. DOI: 10.1107/S0567740873007740 |
0.59 |
|
| 1972 |
Sussman JL, Seeman NC, Kim SH, Berman HM. Crystal structure of a naturally occurring dinucleoside phoaphate: uridylyl 3',5'-adenosine phosphate model for RNA chain folding. Journal of Molecular Biology. 66: 403-21. PMID 5037021 DOI: 10.1016/0022-2836(72)90423-8 |
0.567 |
|
| 1972 |
Seeman NC, Sussman JL, Berman HM, Kim S. Solution of UpA Structure Science. 177: 294-294. DOI: 10.1126/Science.177.4046.294-A |
0.502 |
|
| 1971 |
Seeman NC, Sussman JL, Berman HN, Kim SH. Nucleic acid conformation: crystal structure of a naturally occurring dinucleoside phosphate (UpA). Nature: New Biology. 233: 90-2. PMID 5287004 DOI: 10.1038/Newbio233090A0 |
0.59 |
|
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