Jianzhong Chen, Ph.D. - Publications

Optometry & Vision Science University of Alabama, Birmingham, Birmingham, AL, United States 
Chemistry, Mass Spectrometry, HPLC, Lipidomics, Proteomics, tear film

144 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Wang M, Zhang L, Huo X, Zhang Z, Yuan Q, Li P, Chen J, Zou Y, Wu Z, Zhang W. Catalytic Asymmetric Synthesis of the Anti-COVID-19 Drug Remdesivir. Angewandte Chemie (International Ed. in English). PMID 32870563 DOI: 10.1002/Anie.202011527  0.601
2020 Wang X, Cheng Y, Cai S, Chen J, Xu P, Chen Y, Yu H, Xu T, Zhang S, Li X. Resonant-Cantilever Detected Kinetic/Thermodynamic Parameters for Aptamer-Ligand Binding on Liquid-Solid Interface. Analytical Chemistry. PMID 32551574 DOI: 10.1021/acs.analchem.0c01142  0.62
2020 Ziemanski JF, Chen J, Nichols KK. Evaluation of Cell Harvesting Techniques to Optimize Lipidomic Analysis from Human Meibomian Gland Epithelial Cells in Culture. International Journal of Molecular Sciences. 21. PMID 32384602 DOI: 10.3390/Ijms21093277  0.724
2020 Hu Y, Chen J, Li B, Zhang Z, Gridnev ID, Zhang W. Nickel-Catalyzed Asymmetric Hydrogenation of 2-Amidoacrylates. Angewandte Chemie (International Ed. in English). PMID 31958203 DOI: 10.1002/anie.201916534  0.607
2019 Chen J, Yin B, Pang L, Wang W, Zhang JZH, Zhu T. Binding modes and conformational changes of FK506-binding protein 51 induced by inhibitor bindings: insight into molecular mechanisms based on multiple simulation technologies. Journal of Biomolecular Structure & Dynamics. 1-15. PMID 31198099 DOI: 10.1080/07391102.2019.1624616  0.648
2019 Zhu Z, Chen J, Wang G, Elsherbini A, Zhong L, Jiang X, Qin H, Tripathi P, Zhi W, Spassieva SD, Morris AJ, Bieberich E. Ceramide regulates interaction of Hsd17b4 with Pex5 and function of peroxisomes. Biochimica Et Biophysica Acta. Molecular and Cell Biology of Lipids. PMID 31176039 DOI: 10.1016/J.Bbalip.2019.05.017  0.615
2019 Chen J, Wang X, Pang L, Zhang JZH, Zhu T. Effect of mutations on binding of ligands to guanine riboswitch probed by free energy perturbation and molecular dynamics simulations. Nucleic Acids Research. PMID 31173143 DOI: 10.1093/Nar/Gkz499  0.631
2019 Xie L, Li T, Chen J, Yin D, Wang W, Xie Z. Cone-beam CT assessment of implant-related anatomy landmarks of the anterior mandible in a Chinese population. Surgical and Radiologic Anatomy : Sra. PMID 31069446 DOI: 10.1007/s00276-019-02250-7  0.554
2019 Chen J, Shiyanov P, Green KB. Top-down Mass Spectrometry of Intact Phosphorylated β-casein: Correlation between The Precursor Charge State and Internal Fragments. Journal of Mass Spectrometry : Jms. PMID 30997701 DOI: 10.1002/Jms.4364  0.637
2019 Li B, Chen J, Zhang Z, Gridnev ID, Zhang W. Ni-Catalyzed Asymmetric Hydrogenation of N-Sulfonyl Imines. Angewandte Chemie (International Ed. in English). PMID 30920711 DOI: 10.1002/anie.201902576  0.603
2019 Chen J, Pang L, Wang W, Wang L, Zhang JZH, Zhu T. Decoding molecular mechanism of inhibitor bindings to CDK2 using molecular dynamics simulations and binding free energy calculations. Journal of Biomolecular Structure & Dynamics. 1-23. PMID 30843759 DOI: 10.1080/07391102.2019.1591304  0.638
2019 Chen J, Nichols KK, Wilson L, Barnes S, Nichols JJ. Untargeted lipidomic analysis of human tears: A new approach for quantification of O-acyl-omega hydroxy fatty acids. The Ocular Surface. PMID 30818035 DOI: 10.1016/J.Jtos.2019.02.004  0.762
2019 Chen J, Panthi S. Lipidomic Analysis of Meibomian Gland Secretions from the Tree Shrew: Identification of Candidate Tear Lipids Critical for Reducing Evaporation. Chemistry and Physics of Lipids. PMID 30660743 DOI: 10.1016/J.Chemphyslip.2019.01.003  0.632
2019 Zhou M, He E, Zhang L, Chen J, Zhang Z, Liu Y, Zhang W. Development of a new bicyclic imidazole nucleophilic organocatalyst for direct enantioselective C-acylation Organic Chemistry Frontiers. 6: 3969-3972. DOI: 10.1039/c9qo01025d  0.39
2019 Li G, Pan Y, Liu Y, Xu H, Chen J. Ni/NHC-catalyzed cross-coupling of methyl sulfinates and amines for direct access to sulfinamides Tetrahedron Letters. 60: 151260. DOI: 10.1016/j.tetlet.2019.151260  0.364
2019 Nie Y, Chen J, Zhang W. Rh(I)-catalyzed ring-opening of cyclobutanols via C–C bond activation: Synthesis of cis-olefin with a remote aldehyde Tetrahedron. 75: 130563. DOI: 10.1016/j.tet.2019.130563  0.378
2019 Chen J, Butt NA, Zhang W. The application of the chiral ligand DTBM-SegPHOS in asymmetric hydrogenation Research On Chemical Intermediates. 45: 5959-5974. DOI: 10.1007/s11164-019-04013-w  0.401
2019 Li B, Chen J, Zhang Z, Gridnev ID, Zhang W. Inside Back Cover: Nickel‐Catalyzed Asymmetric Hydrogenation of N ‐Sulfonyl Imines (Angew. Chem. Int. Ed. 22/2019) Angewandte Chemie International Edition. 58: 7495-7495. DOI: 10.1002/ANIE.201905441  0.382
2018 Chen F, Zhang Z, Chen J. Infective endocarditis caused by Lactococcus lactis subsp. lactis and Pediococcus pentosaceus: A case report and literature review. Medicine. 97: e13658. PMID 30558065 DOI: 10.1097/MD.0000000000013658  0.561
2018 Chen J, Zhang Z, Li B, Li F, Wang Y, Zhao M, Gridnev ID, Imamoto T, Zhang W. Pd(OAc)-catalyzed asymmetric hydrogenation of sterically hindered N-tosylimines. Nature Communications. 9: 5000. PMID 30479338 DOI: 10.1038/s41467-018-07462-w  0.6
2018 Panthi S, Chen J, Wilson L, Nichols JJ. Detection of Lipid Mediators of Inflammation in the Human Tear Film. Eye & Contact Lens. PMID 30303825 DOI: 10.1097/Icl.0000000000000551  0.711
2018 Chen J, Nichols KK. Comprehensive Shotgun Lipidomics of Human Meibomian Gland Secretions Using MS/MS with Successive Switching between Acquisition Polarity Modes. Journal of Lipid Research. PMID 30279222 DOI: 10.1194/Jlr.D088138  0.72
2018 Chen J, Peng C, Wang J, Zhu W. Exploring Molecular Mechanism of Allosteric Inhibitor to Relieve Drug Resistance of Multiple Mutations in HIV-1 Protease by Enhanced Conformational Sampling. Proteins. PMID 30260044 DOI: 10.1002/prot.25610  0.633
2018 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. Insight into Selective Mechanism of class of I-BRD9 Inhibitors toward BRD9 Based on Molecular Dynamics Simulations. Chemical Biology & Drug Design. PMID 30225973 DOI: 10.1111/cbdd.13398  0.641
2018 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Electrostatic Interaction-Mediated Conformational Changes of Adipocyte Fatty Acid Binding Protein Probed by Molecular Dynamics Simulation. Journal of Biomolecular Structure & Dynamics. 1-32. PMID 30193557 DOI: 10.1080/07391102.2018.1520648  0.642
2018 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Molecular Dynamics Exploration of Selectivity of Dual Inhibitors 5M7, 65X, and 65Z toward Fatty Acid Binding Proteins 4 and 5. International Journal of Molecular Sciences. 19. PMID 30142969 DOI: 10.3390/ijms19092496  0.649
2018 Ngo W, Chen J, Panthi S, Nichols KK, Nichols JJ. Comparison of Collection Methods for the Measure of Human Meibum and Tear Film-Derived Lipids Using Mass Spectrometry. Current Eye Research. 1-9. PMID 30081661 DOI: 10.1080/02713683.2018.1501803  0.759
2018 Wen K, Wu Z, Chen B, Chen J, Zhang W. Pd(ii)-Catalyzed aerobic 1,2-difunctionalization of conjugated dienes: efficient synthesis of morpholines and 2-morpholones. Organic & Biomolecular Chemistry. PMID 30027979 DOI: 10.1039/c8ob01291a  0.589
2018 Chen J, Wang J, Pang L, Zhu W. Inhibiting mechanism of small molecule toward the p53-MDM2 interaction: A Molecular Dynamics Exploration. Chemical Biology & Drug Design. PMID 29877036 DOI: 10.1111/cbdd.13345  0.635
2018 Sun A, Zhang H, Pang F, Niu G, Chen J, Chen F, Zhang J. Essential genes of the macrophage response to exposure. Cellular & Molecular Biology Letters. 23: 25. PMID 29849669 DOI: 10.1186/s11658-018-0090-4  0.571
2018 Zhang J, Liu C, Wang X, Chen J, Zhang Z, Zhang W. Rhodium-catalyzed asymmetric hydrogenation of β-branched enamides for the synthesis of β-stereogenic amines. Chemical Communications (Cambridge, England). PMID 29796543 DOI: 10.1039/C8Cc02798F  0.591
2018 Ding K, Zhou Z, Hou S, Yuan Y, Zhou S, Zheng X, Chen J, Loftin C, Zheng F, Zhan CG. Structure-based discovery of mPGES-1 inhibitors suitable for preclinical testing in wild-type mice as a new generation of anti-inflammatory drugs. Scientific Reports. 8: 5205. PMID 29581541 DOI: 10.1038/S41598-018-23482-4  0.605
2018 Chen W, Cheng Y, Chen J, Chen J, Jiang K, Zhou Y, Jia L. Pharmacokinetic differences of mifepristone between sexes in animals. Journal of Pharmaceutical and Biomedical Analysis. 154: 108-115. PMID 29544105 DOI: 10.1016/j.jpba.2018.03.008  0.597
2018 Tao P, Poddar S, Sun Z, Hage DS, Chen J. Analysis of Solute-Protein Interactions and Solute-Solute Competition by Zonal Elution Affinity Chromatography. Methods (San Diego, Calif.). PMID 29409783 DOI: 10.1016/J.Ymeth.2018.01.020  0.716
2018 Chen J, Wang X, Zhang JZH, Zhu T. Effect of Substituents in Different Positions of Aminothiazole Hinge-Binding Scaffolds on Inhibitor–CDK2 Association Probed by Interaction Entropy Method Acs Omega. 3: 18052-18064. DOI: 10.1021/ACSOMEGA.8B02354  0.617
2018 Shao Q, Wu L, Chen J, Gridnev ID, Yang G, Xie F, Zhang W. Copper (II)/RuPHOX-Catalyzed Enantioselective Mannich-Type Reaction of Glycine Schiff Bases with Cyclic Ketimines Advanced Synthesis & Catalysis. 360: 4625-4633. DOI: 10.1002/adsc.201800850  0.369
2017 Huo X, Fu J, He X, Chen J, Xie F, Zhang W. Pd/Cu dual catalysis: highly enantioselective access to α-substituted α-amino acids and α-amino amides. Chemical Communications (Cambridge, England). PMID 29256570 DOI: 10.1039/C7Cc08732B  0.586
2017 Chen W, Xiao Y, Chen J, Liu J, Shao J, Li T, Zhu Y, Ma J, Gao Y, Wang J, Xu J, Lu Y, Jia L. Sex-related pharmacokinetic differences and mechanisms of metapristone (RU486 metabolite). Scientific Reports. 7: 17190. PMID 29215040 DOI: 10.1038/s41598-017-17225-0  0.59
2017 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. A Theoretical Insight into Selectivity of Inhibitors toward two Domains of Bromodomain-Containing Protein 4 Using Molecular Dynamics Simulations. Chemical Biology & Drug Design. PMID 29139214 DOI: 10.1111/cbdd.13148  0.643
2017 Chen J, Wang J, Zhu W. Mutation L1196M-induced conformational changes and the drug resistant mechanism of anaplastic lymphoma kinase studied by free energy perturbation and umbrella sampling. Physical Chemistry Chemical Physics : Pccp. PMID 29109998 DOI: 10.1039/c7cp05418a  0.62
2017 Yan F, Liu X, Zhang S, Su J, Zhang Q, Chen J. Computational revelation of Binding Mechanisms of Inhibitors to Endocellular Protein Tyrosine Phosphatase 1B Using Molecular Dynamics Simulations. Journal of Biomolecular Structure & Dynamics. 1-36. PMID 29048995 DOI: 10.1080/07391102.2017.1394221  0.646
2017 Chen J, Tao F, Zhang B, Chen Q, Qiu Y, Luo Q, Gen Y, Meng J, Zhang J, Lu H. Elevated Squamous Cell Carcinoma Antigen, Cytokeratin 19 Fragment, and Carcinoembryonic Antigen Levels in Diabetic Nephropathy. International Journal of Endocrinology. 2017: 5304391. PMID 28744310 DOI: 10.1155/2017/5304391  0.56
2017 Jiang Z, Qian J, Dong H, Yang J, Yu X, Chen J, Chen H, Shi Q, Jia L. The traditional Chinese medicine Achyranthes bidentata and our de novo conception of its metastatic chemoprevention: from phytochemistry to pharmacology. Scientific Reports. 7: 3888. PMID 28634392 DOI: 10.1038/s41598-017-02054-y  0.59
2017 Zhai Y, Chai L, Chen J. The relationship between the expressions of tumor associated fibroblasts Cav-1 and MCT4 and the prognosis of papillary carcinoma of breast. Pakistan Journal of Pharmaceutical Sciences. 30: 263-272. PMID 28625953  0.578
2017 Su J, Liu X, Zhang S, Yan F, Zhang Q, Chen J. A computational insight into binding modes of inhibitors XD29, XD35, and XD28 to bromodomain-containing protein 4 based on molecular dynamics simulations. Journal of Biomolecular Structure & Dynamics. 1-13. PMID 28466681 DOI: 10.1080/07391102.2017.1317666  0.652
2017 Chen J, Keirsey JK, Green KB, Nichols KK. Expression Profiling of Nonpolar Lipids in Meibum From Patients With Dry Eye: A Pilot Study. Investigative Ophthalmology & Visual Science. 58: 2266-2274. PMID 28426869 DOI: 10.1167/Iovs.16-20902  0.697
2017 Chen J, Wang J, Zhu W. Zinc ion-induced conformational changes in new Delphi metallo-β-lactamase 1 probed by molecular dynamics simulations and umbrella sampling. Physical Chemistry Chemical Physics : Pccp. PMID 28079218 DOI: 10.1039/c6cp08105c  0.622
2017 Xu C, Wu Z, Chen J, Xie F, Zhang W. Palladium(II)-catalyzed aerobic intramolecular allylic C H activation for the synthesis of indolines Tetrahedron. 73: 1904-1910. DOI: 10.1016/j.tet.2017.02.040  0.377
2016 Zhang H, Wu F, Li Y, Yang X, Huang J, Lv T, Zhang Y, Chen J, Chen H, Gao Y, Liu G, Jia L. Chitosan-based nanoparticles for improved anticancer efficacy and bioavailability of mifepristone. Beilstein Journal of Nanotechnology. 7: 1861-1870. PMID 28144535 DOI: 10.3762/bjnano.7.178  0.604
2016 Chen J. Functional Roles of Magnesium Binding to Extracellular Signal-Regulated Kinase 2 explored by Molecular Dynamics Simulations and Principal Component Analysis. Journal of Biomolecular Structure & Dynamics. 1-31. PMID 28030988 DOI: 10.1080/07391102.2016.1277783  0.638
2016 Chen X, Chen J, Li B, Yang X, Zeng R, Liu Y, Li T, Ho RJ, Shao J. PLGA-PEG-PLGA triblock copolymeric micelles as oral drug delivery system: In vitro drug release and in vivo pharmacokinetics assessment. Journal of Colloid and Interface Science. 490: 542-552. PMID 27923139 DOI: 10.1016/j.jcis.2016.11.089  0.608
2016 Chen J, Wang J, Zhu W. Molecular Mechanism and Energy Basis of Conformational Diversity of Antibody SPE7 Revealed by Molecular Dynamics Simulation and Principal Component Analysis. Scientific Reports. 6: 36900. PMID 27830740 DOI: 10.1038/srep36900  0.609
2016 Ye C, Zhang W, Wang S, Jiang S, Yu Y, Chen E, Xue D, Chen J, He R. Icariin Promotes Tendon-Bone Healing during Repair of Rotator Cuff Tears: A Biomechanical and Histological Study. International Journal of Molecular Sciences. 17. PMID 27792147 DOI: 10.3390/ijms17111780  0.569
2016 Chen J. Clarifying Binding Difference of ATP and ADP to Extracellular Signal-regulated Kinase 2 by Using Molecular Dynamics Simulations. Chemical Biology & Drug Design. PMID 27696674 DOI: 10.1111/cbdd.12877  0.633
2016 Qian H, Chen J, Pan Y, Chen J. Molecular Modeling Studies of 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors through Receptor-Based 3D-QSAR and Molecular Dynamics Simulations. Molecules (Basel, Switzerland). 21. PMID 27657020 DOI: 10.3390/molecules21091222  0.64
2016 Chen J, Green KB, Nichols KK. Compositional Analysis of Wax Esters in Human Meibomian Gland Secretions by Direct Infusion Electrospray Ionization Mass Spectrometry. Lipids. PMID 27571784 DOI: 10.1007/S11745-016-4183-4  0.723
2016 Liu Y, Chen J, Zhang Z, Qin J, Zhao M, Zhang W. One-pot sequential asymmetric hydrogenation of β-aryl-β-aryloxy acroleins. Organic & Biomolecular Chemistry. 14: 7099-7102. PMID 27439010 DOI: 10.1039/c6ob00871b  0.59
2016 Chen J, Zhang Z, Liu D, Zhang W. Palladium-Catalyzed Chemo- and Enantioselective C-O Bond Cleavage of α-Acyloxy Ketones by Hydrogenolysis. Angewandte Chemie (International Ed. in English). PMID 27312573 DOI: 10.1002/anie.201603590  0.595
2016 Hong Y, Chen J, Zhang Z, Liu Y, Zhang W. Ru-Catalyzed Asymmetric Hydrogenative/Transfer Hydrogenative Desymmetrization of Meso-Epoxy Diketones. Organic Letters. PMID 27213501 DOI: 10.1021/acs.orglett.6b01073  0.594
2016 Guo F, Sun Y, Yang X, Chen X, Zhao B, Zhuang N, Chen J. Growth, Faraday and inverse Faraday characteristics of Tb2Ti2O7 crystal. Optics Express. 24: 5734-5743. PMID 27136771  0.578
2016 Hu Q, Chen J, Zhang Z, Liu Y, Zhang W. Rh-Catalyzed One-Pot Sequential Asymmetric Hydrogenation of α-Dehydroamino Ketones for the Synthesis of Chiral Cyclic trans-β-Amino Alcohols. Organic Letters. 18: 1290-3. PMID 26987883 DOI: 10.1021/acs.orglett.6b00212  0.599
2016 Wang J, Chen J, Zhu Y, Zheng N, Liu J, Xiao Y, Lu Y, Dong H, Xie J, Yu S, Shao J, Jia L. In vitro and in vivo efficacy and safety evaluation of metapristone and mifepristone as cancer metastatic chemopreventive agents. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 78: 291-300. PMID 26898454 DOI: 10.1016/j.biopha.2016.01.017  0.594
2016 Song XR, Yu SX, Jin GX, Wang X, Chen J, Li J, Liu G, Yang HH. Plant Polyphenol-Assisted Green Synthesis of Hollow CoPt Alloy Nanoparticles for Dual-Modality Imaging Guided Photothermal Therapy. Small (Weinheim An Der Bergstrasse, Germany). PMID 26763187 DOI: 10.1002/smll.201503250  0.568
2016 Liu Y, Chen J, Zhang Z, Qin J, Zhao M, Zhang W. ChemInform Abstract: One-Pot Sequential Asymmetric Hydrogenation of β-Aryl-β-aryloxy Acroleins. Cheminform. 47. DOI: 10.1002/CHIN.201649027  0.382
2015 Chen J, Wang J, Zhang Q, Chen K, Zhu W. Probing Origin of Binding Difference of inhibitors to MDM2 and MDMX by Polarizable Molecular Dynamics Simulation and QM/MM-GBSA Calculation. Scientific Reports. 5: 17421. PMID 26616018 DOI: 10.1038/srep17421  0.641
2015 Zhang Z, Hu Q, Wang Y, Chen J, Zhang W. Rh-Catalyzed Asymmetric Hydrogenation of Cyclic α-Dehydroamino Ketones. Organic Letters. PMID 26497221 DOI: 10.1021/acs.orglett.5b02733  0.594
2015 Chen J, Wang X, Zhu T, Zhang Q, Zhang JZ. A Comparative Insight into Amprenavir Resistance of Mutations V32I, G48V, I50V, I54V and I84V in HIV-1 Protease Based on Thermodynamic Integration and MM-PBSA Methods. Journal of Chemical Information and Modeling. PMID 26317593 DOI: 10.1021/Acs.Jcim.5B00173  0.613
2015 Zhu Z, Wu X, Lv B, Wu G, Wang J, Jiang W, Li P, He J, Chen J, Chen M, Bao D, Zhang J, Tan Q, Tang X. A new approach for breeding low-temperature resistant Volvariella volvacea strains: Genome shuffling in edible fungi. Biotechnology and Applied Biochemistry. PMID 26234394 DOI: 10.1002/bab.1420  0.569
2015 Chen J, Green KB, Nichols KK. Characterization of Wax Esters by Electrospray Ionization Tandem Mass Spectrometry: Double Bond Effect and Unusual Product Ions. Lipids. 50: 821-36. PMID 26178197 DOI: 10.1007/S11745-015-4044-6  0.724
2015 Yang J, Lyu B, Zhu W, Chen J, He J, Tang S. [A retrospective cohort comparison of esophageal carcinoma between thoracoscopic and laparoscopic esophagectomy and open esophagectomy]. Zhonghua Wai Ke Za Zhi [Chinese Journal of Surgery]. 53: 378-81. PMID 26082255  0.561
2015 Tang R, Gao L, Kawatani M, Chen J, Cao X, Osada H, Xiang L, Qi J. Neuritogenic Activity of Tetradecyl 2,3-Dihydroxybenzoate Is Mediated through the Insulin-Like Growth Factor 1 Receptor/Phosphatidylinositol 3 Kinase/Mitogen-Activated Protein Kinase Signaling Pathway. Molecular Pharmacology. 88: 326-34. PMID 26013540 DOI: 10.1124/mol.115.097758  0.589
2015 Xiang L, Chi T, Tang Q, Yang X, Ou M, Chen X, Yu X, Chen J, Ho RJ, Shao J, Jia L. A pentacyclic triterpene natural product, ursolic acid and its prodrug US597 inhibit targets within cell adhesion pathway and prevent cancer metastasis. Oncotarget. 6: 9295-312. PMID 25823660  0.597
2015 Miao C, Zhou G, Qin M, Chen J, Li C, He H. [Pulchinenoside inhibits the fibroblast-like synoviocytes apoptosis in adjuvant arthritis rats]. Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences. 40: 144-9. PMID 25769322 DOI: 10.11817/j.issn.1672-7347.2015.02.005  0.565
2015 Pan L, Hu H, Wang X, Yu L, Jiang H, Chen J, Lou Y, Zeng S. Inhibitory effects of neochamaejasmin B on P-glycoprotein in MDCK-hMDR1 cells and molecular docking of NCB binding in P-glycoprotein. Molecules (Basel, Switzerland). 20: 2931-48. PMID 25679052 DOI: 10.3390/molecules20022931  0.602
2015 Gao Y, Li Z, Xie X, Wang C, You J, Mo F, Jin B, Chen J, Shao J, Chen H, Jia L. Dendrimeric anticancer prodrugs for targeted delivery of ursolic acid to folate receptor-expressing cancer cells: synthesis and biological evaluation. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 70: 55-63. PMID 25638419 DOI: 10.1016/j.ejps.2015.01.007  0.605
2015 Chen J, Wang J, Zhang Q, Chen K, Zhu W. A comparative study of trypsin specificity based on QM/MM molecular dynamics simulation and QM/MM GBSA calculation. Journal of Biomolecular Structure & Dynamics. 33: 2606-18. PMID 25562613 DOI: 10.1080/07391102.2014.1003146  0.637
2015 Dong H, Yang X, Xie J, Xiang L, Li Y, Ou M, Chi T, Liu Z, Yu S, Gao Y, Chen J, Shao J, Jia L. UP12, a novel ursolic acid derivative with potential for targeting multiple signaling pathways in hepatocellular carcinoma. Biochemical Pharmacology. 93: 151-62. PMID 25522955 DOI: 10.1016/j.bcp.2014.11.014  0.608
2015 Jiang W, Yao F, He J, Lv B, Fang W, Zhu W, He G, Chen J, He J. Downregulation of VGLL4 in the progression of esophageal squamous cell carcinoma. Tumour Biology : the Journal of the International Society For Oncodevelopmental Biology and Medicine. 36: 1289-97. PMID 25352025 DOI: 10.1007/s13277-014-2701-7  0.58
2015 Chen J, Pitchai K, Birla S, Jones D, Subbiah J, Gonzalez R. Development of a multi-temperature calibration method for measuring dielectric properties of food Ieee Transactions On Dielectrics and Electrical Insulation. 22: 626-634. DOI: 10.1109/Tdei.2014.004182  0.359
2015 Liu S, Chen J. Reaction Mechanism and Kinetics of Methanol Produced to Dimethyl Ether Energy Sources, Part a: Recovery, Utilization, and Environmental Effects. 37: 1591-1596. DOI: 10.1080/15567036.2011.642061  0.37
2014 Chen J, Liang Z, Wang W, Yi C, Zhang S, Zhang Q. Revealing origin of decrease in potency of darunavir and amprenavir against HIV-2 relative to HIV-1 protease by molecular dynamics simulations. Scientific Reports. 4: 6872. PMID 25362963 DOI: 10.1038/srep06872  0.627
2014 Wang R, Wang C, Cao Y, Zhu Z, Yang C, Chen J, Qing FL, Tan W. Trifluoromethylated Nucleic Acid Analogues Capable of Self-Assembly through Hydrophobic Interactions. Chemical Science (Royal Society of Chemistry : 2010). 5: 4076-4081. PMID 25285193 DOI: 10.1039/C4Sc01162G  0.598
2014 Guo M, Pan Y, Zhang R, Cao Y, Chen J, Pan Y. The specific cleavage of lactone linkage to open-loop in cyclic lipopeptide during negative ESI tandem mass spectrometry: the hydrogen bond interaction effect of 4-ethyl guaiacol. Plos One. 9: e104835. PMID 25144459 DOI: 10.1371/journal.pone.0104835  0.623
2014 Chen J, Wang J, Zhu W. Binding modes of three inhibitors 8CA, F8A and I4A to A-FABP studied based on molecular dynamics simulation. Plos One. 9: e99862. PMID 24918907 DOI: 10.1371/journal.pone.0099862  0.648
2014 Lan J, Xu W, Wan Q, Zhang X, Lin J, Chen J, Chen J. Colorimetric determination of sarcosine in urine samples of prostatic carcinoma by mimic enzyme palladium nanoparticles. Analytica Chimica Acta. 825: 63-8. PMID 24767152 DOI: 10.1016/j.aca.2014.03.040  0.589
2014 Chen J, Wang J, Shao J, Gao Y, Xu J, Yu S, Liu Z, Jia L. The unique pharmacological characteristics of mifepristone (RU486): from terminating pregnancy to preventing cancer metastasis. Medicinal Research Reviews. 34: 979-1000. PMID 24585714 DOI: 10.1002/med.21311  0.598
2014 Yu L, Pu J, Zuo M, Zhang X, Cao Y, Chen S, Lou Y, Zhou Q, Hu H, Jiang H, Chen J, Zeng S. Hepatic glucuronidation of isoneochamaejasmin a from the traditional Chinese medicine Stellera chamaejasme L. Root. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 42: 735-43. PMID 24452863 DOI: 10.1124/dmd.113.055962  0.599
2014 Wang J, Chen J, Wan L, Shao J, Lu Y, Zhu Y, Ou M, Yu S, Chen H, Jia L. Synthesis, spectral characterization, and in vitro cellular activities of metapristone, a potential cancer metastatic chemopreventive agent derived from mifepristone (RU486). The Aaps Journal. 16: 289-98. PMID 24442753 DOI: 10.1208/s12248-013-9559-2  0.588
2014 Gao Y, Shao J, Jiang Z, Chen J, Gu S, Yu S, Zheng K, Jia L. Drug enterohepatic circulation and disposition: constituents of systems pharmacokinetics. Drug Discovery Today. 19: 326-40. PMID 24295642 DOI: 10.1016/j.drudis.2013.11.020  0.594
2014 Kang J, Ruan M, Chen X, Liu C, Liu W, Guo F, Chen J. Growth and magneto-optical characteristic of Dy2Ti2O7 crystal Optical Materials. 36: 1266-1269. DOI: 10.1016/J.OPTMAT.2014.03.013  0.356
2014 Kang J, Xu W, Zhang W, Chen X, Liu W, Guo F, Wu S, Chen J. Growth and magneto-optical characteristic of Ho2Ti2O7 crystal Journal of Crystal Growth. 395: 104-108. DOI: 10.1016/j.jcrysgro.2014.03.019  0.356
2014 Kang J, Fang Z, Chen X, Liu W, Guo F, Wu S, Zhang Y, Chen J. Effect of oxygen vacancy concentration on the absorption spectra of Dy2Ti2O7 crystal Journal of Alloys and Compounds. 599: 170-174. DOI: 10.1016/J.JALLCOM.2014.02.081  0.356
2014 Chen J, Liu D, Fan D, Liu Y, Zhang W. ChemInform Abstract: Synthesis of Axially Chiral C10-BridgePHOS Oxides and Their Use as Organocatalysts in Enantioselective Allylations of Aldehydes. Cheminform. 45: no-no. DOI: 10.1002/CHIN.201403024  0.379
2013 Chen J, Wang J, Zhu W, Li G. A computational analysis of binding modes and conformation changes of MDM2 induced by p53 and inhibitor bindings. Journal of Computer-Aided Molecular Design. 27: 965-74. PMID 24264557 DOI: 10.1007/S10822-013-9693-Z  0.635
2013 Chen J, Liu D, Butt N, Li C, Fan D, Liu Y, Zhang W. Palladium-catalyzed asymmetric hydrogenation of α-acyloxy-1-arylethanones. Angewandte Chemie (International Ed. in English). 52: 11632-6. PMID 24038964 DOI: 10.1002/Anie.201306231  0.601
2013 Tang L, Zhao L, Hong L, Yang F, Sheng R, Chen J, Shi Y, Zhou N, Hu Y. Design and synthesis of novel 3-substituted-indole derivatives as selective H3 receptor antagonists and potent free radical scavengers. Bioorganic & Medicinal Chemistry. 21: 5936-44. PMID 23978359 DOI: 10.1016/j.bmc.2013.07.051  0.593
2013 Zhuang N, Liu C, Jia L, Wei L, Cai J, Guo Y, Zhang Y, Hu X, Chen J, Chen X, Tang Y. Clean unzipping by steam etching to synthesize graphene nanoribbons. Nanotechnology. 24: 325604. PMID 23867357 DOI: 10.1088/0957-4484/24/32/325604  0.565
2013 Chen J, Green KB, Nichols KK. Quantitative profiling of major neutral lipid classes in human meibum by direct infusion electrospray ionization mass spectrometry. Investigative Ophthalmology & Visual Science. 54: 5730-53. PMID 23847307 DOI: 10.1167/Iovs.12-10317  0.716
2013 Xie J, Shao J, Lu Y, Chen J, Wang J, Yu S, Jia L. Separation of ginseng active ingredients and their roles in cancer metastasis supplementary therapy. Current Drug Metabolism. 14: 616-23. PMID 23701161  0.59
2013 Dong X, Zhao Y, Huang X, Lin K, Chen J, Wei E, Liu T, Hu Y. Structure-based drug design using GPCR homology modeling: toward the discovery of novel selective CysLT2 antagonists. European Journal of Medicinal Chemistry. 62: 754-63. PMID 23455026 DOI: 10.1016/j.ejmech.2013.01.041  0.606
2013 Li C, Chen J, Fu G, Liu D, Liu Y, Zhang W. ChemInform Abstract: Highly Enantioselective Hydrogenation of N-Unprotected Indoles Using (S)-C10-BridgePHOS as the Chiral Ligand. Cheminform. 44: no-no. DOI: 10.1002/CHIN.201349130  0.406
2012 Fu T, Min H, Xu Y, Chen J, Li G. Molecular dynamic simulation insights into the normal state and restoration of p53 function. International Journal of Molecular Sciences. 13: 9709-40. PMID 22949826 DOI: 10.3390/Ijms13089709  0.617
2012 Han Z, Liao L, Wu Y, Pan H, Shen S, Chen J. Synthesis and photocatalytic application of oriented hierarchical ZnO flower-rod architectures. Journal of Hazardous Materials. 217: 100-6. PMID 22459971 DOI: 10.1016/j.jhazmat.2012.02.074  0.574
2012 Liu D, Sui Y, Wang T, Huang C, Chen J, You X. Two isomorphous Mn(II) and Co(II) 5-amino-tetrazolate coordination polymers with magnetic Δ-chains: crystal structures and magnetic properties. Dalton Transactions (Cambridge, England : 2003). 41: 5301-6. PMID 22411404 DOI: 10.1039/c2dt12495e  0.566
2012 Chen J, Zhang D, Zhang Y, Li G. Computational studies of difference in binding modes of peptide and non-peptide inhibitors to MDM2/MDMX based on molecular dynamics simulations. International Journal of Molecular Sciences. 13: 2176-95. PMID 22408446 DOI: 10.3390/ijms13022176  0.627
2012 Chen J, Shiyanov P, Schlager JJ, Green KB. A pseudo MS3 approach for identification of disulfide-bonded proteins: uncommon product ions and database search. Journal of the American Society For Mass Spectrometry. 23: 225-43. PMID 22170466 DOI: 10.1007/S13361-011-0294-6  0.639
2011 Dong X, Zhou X, Jing H, Chen J, Liu T, Yang B, He Q, Hu Y. Pharmacophore identification, virtual screening and biological evaluation of prenylated flavonoids derivatives as PKB/Akt1 inhibitors. European Journal of Medicinal Chemistry. 46: 5949-58. PMID 22027102 DOI: 10.1016/j.ejmech.2011.10.006  0.592
2011 Chen J, Wang J, Xu B, Zhu W, Li G. Insight into mechanism of small molecule inhibitors of the MDM2-p53 interaction: molecular dynamics simulation and free energy analysis. Journal of Molecular Graphics & Modelling. 30: 46-53. PMID 21764342 DOI: 10.1016/J.Jmgm.2011.06.003  0.642
2011 Ou L, Han S, Ding W, Jia P, Yang B, Medina-Franco JL, Giulianotti MA, Chen JZ, Yu Y. Parallel synthesis of novel antitumor agents: 1,2,3-triazoles bearing biologically active sulfonamide moiety and their 3D-QSAR. Molecular Diversity. 15: 927-46. PMID 21744258 DOI: 10.1007/s11030-011-9324-3  0.389
2011 Chen J, Green-Church KB, Nichols KK. Author response: On the presence of (O-acyl)-omega-hydroxy fatty acids and their esters in human meibomian gland secretions. Investigative Ophthalmology & Visual Science. 52: 1894-5. PMID 21450923 DOI: 10.1167/Iovs.11-7359  0.736
2011 Lu J, Fu C, Chen J. Structure, growth, and optical properties of TbAl3(BO3)4 single crystal. Applied Optics. 50: 116-9. PMID 21221169  0.578
2011 Ou L, Han S, Ding W, Chen Z, Ye Z, Yang H, Zhang G, Lou Y, Chen JZ, Yu Y. Design, synthesis and 3D-QSAR study of cytotoxic flavonoid derivatives. Molecular Diversity. 15: 665-75. PMID 21080070 DOI: 10.1007/s11030-010-9289-7  0.394
2011 Mei M, Cao L, He Y, Zhang R, Guo F, Zhuang N, Chen J. Growth and magneto-optical properties of CaTbAlO4 crystal Advanced Materials Research. 306: 1722-1727. DOI: 10.4028/www.scientific.net/AMR.306-307.1722  0.373
2011 Lu J, Guo F, Chen J. Growth and characteristic of Sr3Tb(BO3)3 crystal Journal of Crystal Growth. 314: 157-162. DOI: 10.1016/j.jcrysgro.2010.12.018  0.357
2011 He Y, Cao L, Zhang R, Wu X, Chen J. Growth and Magneto-Optical Properties of Li2MoO4·1.8Tb2(MoO4)3 Crystal Journal of Inorganic and Organometallic Polymers and Materials. 22: 1-5. DOI: 10.1007/s10904-011-9618-z  0.357
2010 Chen J, Green-Church KB, Nichols KK. Shotgun lipidomic analysis of human meibomian gland secretions with electrospray ionization tandem mass spectrometry. Investigative Ophthalmology & Visual Science. 51: 6220-31. PMID 20671273 DOI: 10.1167/Iovs.10-5687  0.72
2010 Hou J, Pan B, Niu X, Chen J, Xing B. Sulfamethoxazole sorption by sediment fractions in comparison to pyrene and bisphenol A. Environmental Pollution (Barking, Essex : 1987). 158: 2826-32. PMID 20609505 DOI: 10.1016/J.Envpol.2010.06.023  0.573
2010 Chen J, Shiyanov P, Zhang L, Schlager JJ, Green-Church KB. Top-down characterization of a native highly intralinked protein: concurrent cleavages of disulfide and protein backbone bonds. Analytical Chemistry. 82: 6079-89. PMID 20560528 DOI: 10.1021/Ac1006766  0.637
2010 Chen JZ, Chou GX, Wang CH, Yang L, Bligh SW, Wang ZT. Characterization of new metabolites from in vivo biotransformation of norisoboldine by liquid chromatography/mass spectrometry and NMR spectroscopy. Journal of Pharmaceutical and Biomedical Analysis. 52: 687-93. PMID 20223612 DOI: 10.1016/j.jpba.2010.02.008  0.423
2010 Chen J, Dai J, Zhang H, Wang C, Zhou G, Han Z, Liu Z. Bioaccumulation of microcystin and its oxidative stress in the apple (Malus pumila). Ecotoxicology (London, England). 19: 796-803. PMID 20052542 DOI: 10.1007/s10646-009-0456-5  0.575
2010 Chen J, Zhang S, Liu X, Zhang Q. Insights into drug resistance of mutations D30N and I50V to HIV-1 protease inhibitor TMC-114: free energy calculation and molecular dynamic simulation. Journal of Molecular Modeling. 16: 459-68. PMID 19629548 DOI: 10.1007/s00894-009-0553-7  0.624
2010 Chen J, Green-Church KB, Nichols KK. Re-on the presence and role of polar lipids in meibum Investigative Ophthalmology and Visual Science. 51: 6910-6911. DOI: 10.1167/Iovs.10-6547  0.715
2009 Chen J, Chou G, Yang L, Wang C, Wang Z. [Determination of norisoboldine in Radix Lindera by RP-HPLC]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. 34: 2774-6. PMID 20209913  0.582
2009 Chen J, Schiel JE, Hage DS. Noncompetitive peak decay analysis of drug-protein dissociation by high-performance affinity chromatography. Journal of Separation Science. 32: 1632-41. PMID 19472288 DOI: 10.1002/Jssc.200900074  0.781
2009 Chen J, Yang M, Hu G, Shi S, Yi C, Zhang Q. Insights into the functional role of protonation states in the HIV-1 protease-BEA369 complex: molecular dynamics simulations and free energy calculations. Journal of Molecular Modeling. 15: 1245-52. PMID 19294437 DOI: 10.1007/s00894-009-0452-y  0.637
2009 GAO L, LIN S, SUN X, CHEN J. Growth and characterization of Nd:Sr0.95Ba0.05WO4 single crystal Journal of Rare Earths. 27: 71-75. DOI: 10.1016/S1002-0721(08)60194-5  0.36
2008 Chen J, Muggleton S, Santos J. Learning Probabilistic Logic Models from Probabilistic Examples. Machine Learning. 73: 55-85. PMID 19888348 DOI: 10.1007/s10994-008-5076-4  0.55
2008 Mao S, Probst D, Werner S, Chen J, Xie X, Brummond KM. Diverging Rh(I)-catalyzed carbocylization strategy to prepare a library of unique cyclic ethers. Journal of Combinatorial Chemistry. 10: 235-46. PMID 18271514 DOI: 10.1021/Cc7001843  0.602
2007 Chen J, Anderson M, Misek DE, Simeone DM, Lubman DM. Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry. Journal of Chromatography. A. 1162: 117-25. PMID 17434173 DOI: 10.1016/J.Chroma.2007.03.096  0.7
2007 Zhu J, Zhong F, Zhuang N, Chen J. Effect of Calcium on Nd:GdVO4 single crystal Materials Letters. 61: 374-379. DOI: 10.1016/j.matlet.2006.04.065  0.365
2007 Zhang W, Guo F, Chen J. Growth and characterization of Tb3Ga5−xAlxO12 single crystal Journal of Crystal Growth. 306: 195-199. DOI: 10.1016/j.jcrysgro.2007.04.039  0.36
2006 Chen J, Hage DS. Quantitative studies of allosteric effects by biointeraction chromatography: analysis of protein binding for low-solubility drugs. Analytical Chemistry. 78: 2672-83. PMID 16615779 DOI: 10.1021/Ac052017B  0.733
2006 Chen J, Fitos I, Hage DS. Chromatographic analysis of allosteric effects between ibuprofen and benzodiazepines on human serum albumin. Chirality. 18: 24-36. PMID 16278829 DOI: 10.1002/Chir.20216  0.724
2006 Gao S, Chen W, Wang G, Chen J. Synthesis, crystal growth and characterization of organic NLO material: N-(4-nitrophenyl)-N-methyl-2-aminoacetonitrile (NPAN) Journal of Crystal Growth. 297: 361-365. DOI: 10.1016/j.jcrysgro.2006.09.047  0.359
2005 Lin XS, Chen JL, Zhuang NF, Zhao B, Chen JZ. Growth and characterization of Yb:BaWO4 single crystal Journal of Crystal Growth. 277: 223-227. DOI: 10.1016/j.jcrysgro.2004.12.158  0.375
2004 Chen J, Hage DS. Quantitative analysis of allosteric drug-protein binding by biointeraction chromatography. Nature Biotechnology. 22: 1445-8. PMID 15502818 DOI: 10.1038/Nbt1022  0.734
2004 Chen J, Ohnmacht C, Hage DS. Studies of phenytoin binding to human serum albumin by high-performance affinity chromatography. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 809: 137-45. PMID 15282104 DOI: 10.1016/J.Jchromb.2004.06.012  0.775
2004 Chen J, Ohnmacht CM, Hage DS. Characterization of drug interactions with soluble beta-cyclodextrin by high-performance affinity chromatography. Journal of Chromatography. A. 1033: 115-26. PMID 15072296 DOI: 10.1016/J.Chroma.2004.01.032  0.755
2003 Lin S, Li L, Chen J, Chen Y. Solution growth of an ultrasoft X-ray spectroscopy organic crystal hexadecyl hydrogen maleate (HHM) Journal of Crystal Growth. 249: 341-344. DOI: 10.1016/S0022-0248(02)02106-1  0.374
2001 Chen J, Smith DL. Amide hydrogen exchange shows that malate dehydrogenase is a folded monomer at pH 5. Protein Science : a Publication of the Protein Society. 10: 1079-83. PMID 11316888 DOI: 10.1110/Ps.53201  0.39
2000 Chen J, Smith DL. Unfolding and disassembly of the chaperonin GroEL occurs via a tetradecameric intermediate with a folded equatorial domain. Biochemistry. 39: 4250-8. PMID 10757973  0.393
2000 Jiang HL, Huang XQ, Rong SB, Luo XM, Chen JZ, Tang Y, Chen KX, Zhu YC, Jin WQ, Chi ZQ, Ji RY, Cao Y. Theoretical studies on opioid receptors and ligands. I. Molecular modeling and QSAR studies on the interaction mechanism of fentanyl analogs binding to ?-opioid receptor International Journal of Quantum Chemistry. 78: 285-293. DOI: 10.1002/(SICI)1097-461X(2000)78:4<285::AID-QUA11>3.0.CO;2-I  0.394
1998 Chen J, Smith DL, Griep MA. The role of the 6 lysines and the terminal amine of Escherichia coli single-strand binding protein in its binding of single-stranded DNA. Protein Science : a Publication of the Protein Society. 7: 1781-8. PMID 10082375 DOI: 10.1002/Pro.5560070813  0.448
1998 Wang Q, Jiang H, Chen J, Chen K, Ji R. On the possible reaction pathway for the acylation of AChE-catalyzed hydrolysis of ACh: Semiempirical quantum chemical study International Journal of Quantum Chemistry. 70: 515-525. DOI: 10.1002/(SICI)1097-461X(1998)70:3<515::AID-QUA7>3.0.CO;2-X  0.368
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