Akshay Kulkarni - Related publications

2019- CSIR-National Chemical Laboratory, Pune, India 
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50 most relevant papers in past 60 days:
Year Citation  Score
2021 Broichhagen J, Kilian N. Chemical biology tools to investigate malaria parasites. Chembiochem : a European Journal of Chemical Biology. PMID 33570245 DOI: 10.1002/cbic.202000882   
2021 Miguel-Blanco C, Murithi JM, Benavente ED, Angrisano F, Sala KA, van Schalkwyk DA, Vanaerschot M, Schwach F, Fuchter MJ, Billker O, Sutherland CJ, Campino SG, Clark TG, Blagborough AM, Fidock DA, et al. The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. Scientific Reports. 11: 1888. PMID 33479319 DOI: 10.1038/s41598-021-81343-z   
2021 Adderley J, Williamson T, Doerig C. Parasite and Host Erythrocyte Kinomics of Plasmodium Infection. Trends in Parasitology. PMID 33593681 DOI: 10.1016/j.pt.2021.01.002   
2021 Burgert L, Zaloumis S, Dini S, Marquart L, Cao P, Cherkaoui M, Gobeau N, McCarthy J, Simpson JA, Möhrle JJ, Penny MA. Parasite-host dynamics throughout antimalarial drug development stages complicate the translation of parasite clearance. Antimicrobial Agents and Chemotherapy. PMID 33526486 DOI: 10.1128/AAC.01539-20   
2021 Oberstaller J, Otto TD, Rayner JC, Adams JH. Essential Genes of the Parasitic Apicomplexa. Trends in Parasitology. PMID 33419671 DOI: 10.1016/j.pt.2020.11.007   
2021 Singh MK, Tessarin-Almeida G, Dias BKM, Pereira PS, Costa F, Przyborski JM, Garcia CRS. A nuclear protein, PfMORC confers melatonin dependent synchrony of the human malaria parasite P. falciparum in the asexual stage. Scientific Reports. 11: 2057. PMID 33479315 DOI: 10.1038/s41598-021-81235-2   
2021 Brian JI, Aldridge DC. Abundance data applied to a novel model invertebrate host shed new light on parasite community assembly in nature. The Journal of Animal Ecology. PMID 33522596 DOI: 10.1111/1365-2656.13436   
2021 Bansal P, Antil N, Kumar M, Yamaryo-Botté Y, Rawat RS, Pinto S, Datta KK, Katris NJ, Botté CY, Prasad TSK, Sharma P. Protein kinase TgCDPK7 regulates vesicular trafficking and phospholipid synthesis in Toxoplasma gondii. Plos Pathogens. 17: e1009325. PMID 33635921 DOI: 10.1371/journal.ppat.1009325   
2021 Vanheer LN, Kafsack BFC. Activity Comparison of Epigenetic Modulators against the Hemoprotozoan Parasites and . Acs Infectious Diseases. PMID 33599488 DOI: 10.1021/acsinfecdis.0c00853   
2021 Moreno Y, Geary TG, Tritten L. When Secretomes Meet Anthelmintics: Lessons for Therapeutic Interventions. Trends in Parasitology. PMID 33563557 DOI: 10.1016/j.pt.2021.01.007   
2021 Milne K, Ivens A, Reid AJ, Lotkowska ME, O'Toole A, Sankaranarayanan G, Munoz Sandoval D, Nahrendorf W, Regnault C, Edwards NJ, Silk SE, Payne RO, Minassian AM, Venkatraman N, Sanders MJ, et al. Mapping immune variation and gene switching in naive hosts infected with . Elife. 10. PMID 33648633 DOI: 10.7554/eLife.62800   
2021 Tiwari S, Sharma N, Sharma GP, Mishra N. Redox interactome in malaria parasite Plasmodium falciparum. Parasitology Research. PMID 33459846 DOI: 10.1007/s00436-021-07051-9   
2021 Hamada S, Pionneau C, Parizot C, Silvie O, Chardonnet S, Marinach C. In-depth proteomic analysis of Plasmodium berghei sporozoites using trapped ion mobility spectrometry with parallel accumulation-serial fragmentation. Proteomics. e2000305. PMID 33452840 DOI: 10.1002/pmic.202000305   
2021 Molgora BM, Rai AK, Sweredoski MJ, Moradian A, Hess S, Johnson PJ. A Novel Trichomonas vaginalis Surface Protein Modulates Parasite Attachment via Protein:Host Cell Proteoglycan Interaction. Mbio. 12. PMID 33563826 DOI: 10.1128/mBio.03374-20   
2021 Mills B, Isaac RE, Foster R. Metalloaminopeptidases of the Protozoan Parasite as Targets for the Discovery of Novel Antimalarial Drugs. Journal of Medicinal Chemistry. PMID 33534577 DOI: 10.1021/acs.jmedchem.0c01721   
2021 Bui HTN, Passecker A, Brancucci NMB, Voss TS. Investigation of Heterochromatin Protein 1 Function in the Malaria Parasite Plasmodium falciparum Using a Conditional Domain Deletion and Swapping Approach. Msphere. 6. PMID 33536327 DOI: 10.1128/mSphere.01220-20   
2021 Oboh MA, Ndiaye T, Diongue K, Ndiaye YD, Sy M, Deme AB, Diallo MA, Yade MS, Volkman SK, Badiane AS, Amambua-Ngwa A, Ndiaye D. Allelic diversity of MSP1 and MSP2 repeat loci correlate with levels of malaria endemicity in Senegal and Nigerian populations. Malaria Journal. 20: 38. PMID 33436004 DOI: 10.1186/s12936-020-03563-4   
2021 Gagne RB, Crooks K, Craft ME, Chiu ES, Fountain-Jones NM, Malmberg JL, Carver S, Funk WC, VandeWoude S. Parasites as conservation tools. Conservation Biology : the Journal of the Society For Conservation Biology. PMID 33586245 DOI: 10.1111/cobi.13719   
2021 Mitchell RM, Zhou Z, Sheth M, Sergent S, Frace M, Nayak V, Hu B, Gimnig J, Ter Kuile F, Lindblade K, Slutsker L, Hamel MJ, Desai M, Otieno K, Kariuki S, et al. Development of a new barcode-based, multiplex-PCR, next-generation-sequencing assay and data processing and analytical pipeline for multiplicity of infection detection of Plasmodium falciparum. Malaria Journal. 20: 92. PMID 33593329 DOI: 10.1186/s12936-021-03624-2   
2021 Nguyen W, Dans MG, Ngo A, Gancheva MR, Romeo O, Duffy S, de Koning-Ward TF, Lowes KN, Sabroux HJ, Avery VM, Wilson DW, Gilson PR, Sleebs BE. Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion. European Journal of Medicinal Chemistry. 214: 113253. PMID 33610028 DOI: 10.1016/j.ejmech.2021.113253   
2021 Quinn J, Lee S, Greeley D, Gehman A, Kuris AM, Wood CL. Long-term change in the parasite burden of shore crabs ( and ) on the northwestern Pacific coast of North America. Proceedings. Biological Sciences. 288: 20203036. PMID 33622132 DOI: 10.1098/rspb.2020.3036   
2021 Lauringson M, Nousiainen I, Kahar S, Burimski O, Gross R, Kaart T, Vasemägi A. Climate change-driven disease in sympatric hosts: Temporal dynamics of parasite burden and proliferative kidney disease in wild brown trout and Atlantic salmon. Journal of Fish Diseases. PMID 33428789 DOI: 10.1111/jfd.13330   
2021 Cassiano GC, Tavella TA, Nascimento MN, Rodrigues DA, Cravo PVL, Andrade CH, Costa FTM. Targeting malaria protein kinases. Advances in Protein Chemistry and Structural Biology. 124: 225-274. PMID 33632466 DOI: 10.1016/bs.apcsb.2020.10.004   
2021 Nørgaard LS, Zilio G, Saade C, Gougat-Barbera C, Hall MD, Fronhofer EA, Kaltz O. An evolutionary trade-off between parasite virulence and dispersal at experimental invasion fronts. Ecology Letters. PMID 33583087 DOI: 10.1111/ele.13692   
2021 Martinez-Peinado N, Martori C, Cortes-Serra N, Sherman J, Rodriguez A, Gascon J, Alberola J, Pinazo MJ, Rodriguez-Cortes A, Alonso-Padilla J. Anti- Activity of Metabolism Modifier Compounds. International Journal of Molecular Sciences. 22. PMID 33445756 DOI: 10.3390/ijms22020688   
2021 Simwela NV, Hughes KR, Rennie MT, Barrett MP, Waters AP. Mammalian Deubiquitinating Enzyme Inhibitors Display and Activity against Malaria Parasites and Potentiate Artemisinin Action. Acs Infectious Diseases. PMID 33400499 DOI: 10.1021/acsinfecdis.0c00580   
2021 Rashidi S, Mansouri R, Ali-Hassanzadeh M, Mojtahedi Z, Shafiei R, Savardashtaki A, Hamidizadeh N, Karimazar M, Nguewa P, Manzano-Román R. The host mTOR pathway and parasitic diseases pathogenesis. Parasitology Research. PMID 33534053 DOI: 10.1007/s00436-021-07070-6   
2021 Tewari SG, Rajaram K, Swift RP, Reifman J, Prigge ST, Wallqvist A. Metabolic survival adaptations of exposed to sub-lethal doses of fosmidomycin. Antimicrobial Agents and Chemotherapy. PMID 33495219 DOI: 10.1128/AAC.02392-20   
2021 E B, Y PR, K B K. A review on Development and Characterization of a Cost-Effective Targeted Quality-Driven Antimalarial Product with an Emphasis on Phytosomes. Current Drug Targets. PMID 33563191 DOI: 10.2174/1389450122666210204203132   
2021 Chen J, Wang FK, He ZX, Bai Y. Progress in the Study of Epidemiologic Characteristics and Influencing Factors of Asymptomatic Malaria Infection in Africa. Alternative Therapies in Health and Medicine. PMID 33620333   
2021 Dekel E, Yaffe D, Rosenhek-Goldian I, Ben-Nissan G, Ofir-Birin Y, Morandi MI, Ziv T, Sisquella X, Pimentel MA, Nebl T, Kapp E, Ohana Daniel Y, Karam PA, Alfandari D, Rotkopf R, et al. 20S proteasomes secreted by the malaria parasite promote its growth. Nature Communications. 12: 1172. PMID 33608523 DOI: 10.1038/s41467-021-21344-8   
2021 Chakrabarti M, Joshi N, Kumari G, Singh P, Shoaib R, Munjal A, Kumar V, Behl A, Abid M, Garg S, Gupta S, Singh S. Interaction of Plasmodium falciparum apicortin with α- and β-tubulin is critical for parasite growth and survival. Scientific Reports. 11: 4688. PMID 33633135 DOI: 10.1038/s41598-021-83513-5   
2021 Li R, Ling D, Tang T, Huang Z, Wang M, Ding Y, Liu T, Wei H, Xu W, Mao F, Zhu J, Li X, Jiang L, Li J. Discovery of Novel HDAC1 Inhibitors with Dual-Stage Antimalarial Potency and Improved Safety Based on the Clinical Anticancer Drug Candidate Quisinostat. Journal of Medicinal Chemistry. PMID 33541085 DOI: 10.1021/acs.jmedchem.0c02104   
2021 Zhang K, Jiang N, Chen H, Zhang N, Sang X, Feng Y, Chen R, Chen Q. TatD DNases of African trypanosomes confer resistance to host neutrophil extracellular traps. Science China. Life Sciences. PMID 33420923 DOI: 10.1007/s11427-020-1854-2   
2021 Li MI, Mailepessov D, Vythilingam I, Lee V, Lam P, Ng LC, Tan CH. Prevalence of simian malaria parasites in macaques of Singapore. Plos Neglected Tropical Diseases. 15: e0009110. PMID 33493205 DOI: 10.1371/journal.pntd.0009110   
2021 Lawong A, Gahalawat S, Okombo J, Striepen J, Yeo T, Mok S, Deni I, Bridgford JL, Niederstrasser H, Zhou A, Posner B, Wittlin S, Gamo FJ, Crespo B, Churchyard A, et al. Novel Antimalarial Tetrazoles and Amides Active against the Hemoglobin Degradation Pathway in . Journal of Medicinal Chemistry. PMID 33620219 DOI: 10.1021/acs.jmedchem.0c02022   
2021 Sánchez CA, Ragonese IG, de Roode JC, Altizer S. Thermal tolerance and environmental persistence of a protozoan parasite in monarch butterflies. Journal of Invertebrate Pathology. 107544. PMID 33582107 DOI: 10.1016/j.jip.2021.107544   
2021 Gibson AK, Nguyen AE. Does genetic diversity protect host populations from parasites? A meta-analysis across natural and agricultural systems. Evolution Letters. 5: 16-32. PMID 33552533 DOI: 10.1002/evl3.206   
2021 McGovern OL, Rivera-Cuevas Y, Carruthers VB. Emerging Mechanisms of Endocytosis in . Life (Basel, Switzerland). 11. PMID 33503859 DOI: 10.3390/life11020084   
2021 Ribbiso KA, Heller LE, Taye A, Julian E, Willems AV, Roepe PD. Artemisinin - Based Drugs Target the heme-detoxification pathway. Antimicrobial Agents and Chemotherapy. PMID 33495226 DOI: 10.1128/AAC.02137-20   
2021 Dorjsuren D, Eastman RT, Wicht KJ, Jansen D, Talley DC, Sigmon BA, Zakharov AV, Roncal N, Girvin AT, Antonova-Koch Y, Will PM, Shah P, Sun H, Klumpp-Thomas C, Mok S, et al. Chemoprotective antimalarials identified through quantitative high-throughput screening of Plasmodium blood and liver stage parasites. Scientific Reports. 11: 2121. PMID 33483532 DOI: 10.1038/s41598-021-81486-z   
2021 Corbett Y, Parapini S, Perego F, Messina V, Delbue S, Misiano P, Falchi M, Silvestrini F, Taramelli D, Basilico N, D'Alessandro S. Phagocytosis and activation of bone marrow-derived macrophages by Plasmodium falciparum gametocytes. Malaria Journal. 20: 81. PMID 33568138 DOI: 10.1186/s12936-021-03589-2   
2021 Fabbri C, Trindade AO, Andrade FS, Souza MF, Ríos-Velásquez CM, Lacerda MVG, Monteiro WM, Costa FTM, Amino R, Lopes SCP. Transmission-blocking compound candidates against Plasmodium vivax using P. berghei as an initial screening. Memorias Do Instituto Oswaldo Cruz. 116: e200513. PMID 33566952 DOI: 10.1590/0074-02760200513   
2021 Ouji M, Nguyen M, Mustière R, Jimenez T, Augereau JM, Benoit-Vical F, Deraeve C. Novel molecule combinations and corresponding hybrids targeting artemisinin-resistant Plasmodium falciparum parasites. Bioorganic & Medicinal Chemistry Letters. 127884. PMID 33636304 DOI: 10.1016/j.bmcl.2021.127884   
2021 Walsh B, Hill KL. Right place, right time: Environmental sensing and signal transduction directs cellular differentiation and motility in Trypanosoma brucei. Molecular Microbiology. PMID 33434370 DOI: 10.1111/mmi.14682   
2021 Ben Khalaf N, Pham S, Romeo G, Abdelghany S, Intagliata S, Sedillo P, Salerno L, Gonzales J, Fathallah DM, Perkins DJ, Hurwitz I, Pittalà V. A computer-aided approach to identify novel Leishmania major protein disulfide isomerase inhibitors for treatment of leishmaniasis. Journal of Computer-Aided Molecular Design. PMID 33615401 DOI: 10.1007/s10822-021-00374-w   
2021 Wang Y, Wu X, Wang Z, Chen T, Zhou S, Chen J, Pang L, Ye X, Shi M, Huang J, Chen X. Symbiotic bracovirus of a parasite manipulates host lipid metabolism via tachykinin signaling. Plos Pathogens. 17: e1009365. PMID 33647060 DOI: 10.1371/journal.ppat.1009365   
2021 Tajiri M. Phage Display Screening for Alba Superfamily Proteins from the Human Malaria Parasite, Plasmodium falciparum Reveals a High Level of Association with Protein Modification Pathways and Hints at New Drug Targets. Acta Parasitologica. PMID 33559027 DOI: 10.1007/s11686-021-00339-x   
2021 Lizarraga A, Muñoz D, Strobl-Mazzulla PH, de Miguel N. Toward incorporating epigenetics into regulation of gene expression in the parasite Trichomonas vaginalis. Molecular Microbiology. PMID 33599017 DOI: 10.1111/mmi.14704   
2021 Reader J, van der Watt ME, Taylor D, Le Manach C, Mittal N, Ottilie S, Theron A, Moyo P, Erlank E, Nardini L, Venter N, Lauterbach S, Bezuidenhout B, Horatscheck A, van Heerden A, et al. Multistage and transmission-blocking targeted antimalarials discovered from the open-source MMV Pandemic Response Box. Nature Communications. 12: 269. PMID 33431834 DOI: 10.1038/s41467-020-20629-8