Robert K Ernst - Publications

Affiliations: 
Microbial Pathogenesis University of Maryland Dental School, Baltimore, MD, United States 

83 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Sengyee S, Yoon SH, West TE, Ernst RK, Chantratita N. Lipopolysaccharides of different species with different lipid A structures induce TLR4 activation and react with melioidosis patient sera. Infection and Immunity. PMID 31548320 DOI: 10.1128/IAI.00692-19  0.72
2019 Barker W, Nemeth A, Brackett S, Basak A, Chandler CE, Jania L, Zuercher W, Melander RJ, Koller B, Ernst RK, Melander C. Repurposing Eukaryotic Kinase Inhibitors as Colistin Adjuvants in Gram-negative Bacteria. Acs Infectious Diseases. PMID 31434474 DOI: 10.1021/acsinfecdis.9b00212  0.72
2019 Ryu SY, Wendt GA, Chandler CE, Ernst RK, Goodlett DR. Model-based Spectral Library Approach for Bacterial Identification via Membrane Glycolipids. Analytical Chemistry. PMID 31369253 DOI: 10.1021/acs.analchem.9b03340  0.84
2019 Martin S, Melander RJ, Brackett C, Scott AJ, Chandler CE, Nguyen C, Minrovic B, Harrill S, Ernst RK, Manoil C, Melander C. Small Molecule Potentiation of Gram-positive Selective Antibiotics Against Acinetobacter baumannii. Acs Infectious Diseases. PMID 31002491 DOI: 10.1021/acsinfecdis.9b00067  0.84
2019 Kutschera A, Dawid C, Gisch N, Schmid C, Raasch L, Gerster T, Schäffer M, Smakowska-Luzan E, Belkhadir Y, Vlot AC, Chandler CE, Schellenberger R, Schwudke D, Ernst RK, Dorey S, et al. Bacterial medium-chain 3-hydroxy fatty acid metabolites trigger immunity in plants. Science (New York, N.Y.). 364: 178-181. PMID 30975887 DOI: 10.1126/science.aau1279  0.72
2019 Barker WT, Chandler CE, Melander RJ, Ernst RK, Melander C. Tryptamine derivatives disarm colistin resistance in polymyxin-resistant gram-negative bacteria. Bioorganic & Medicinal Chemistry. PMID 30898435 DOI: 10.1016/j.bmc.2019.03.019  0.72
2019 Khan MM, Chattagul S, Tran BQ, Freiberg JA, Nita-Lazar A, Shirtliff ME, Sermswan RW, Ernst RK, Goodlett DR. Temporal proteomic profiling reveals changes that support Burkholderia biofilms. Pathogens and Disease. PMID 30759239 DOI: 10.1093/femspd/ftz005  0.84
2018 Liang T, Leung LM, Opene B, Fondrie WE, Lee YI, Chandler CE, Yoon SH, Doi Y, Ernst RK, Goodlett DR. Rapid microbial identification and antibiotic resistance detection by mass spectrometric analysis of membrane lipids. Analytical Chemistry. PMID 30571097 DOI: 10.1021/acs.analchem.8b02611  0.84
2018 Leung LM, McElheny CL, Gardner FM, Chandler CE, Bowler SL, Mettus RT, Spychala CN, Fowler EL, Opene BNA, Myers RA, Goodlett DR, Doi Y, Ernst RK. A Prospective Study of Complex Isolates and Colistin Susceptibility Monitoring by Mass Spectrometry of Microbial Membrane Glycolipids. Journal of Clinical Microbiology. PMID 30567747 DOI: 10.1128/JCM.01100-18  0.84
2018 Chandler CE, Horspool AM, Hill PJ, Wozniak DJ, Schertzer JW, Rasko DA, Ernst RK. Genomic and phenotypic diversity among ten laboratory isolates of PAO1. Journal of Bacteriology. PMID 30530517 DOI: 10.1128/JB.00595-18  0.72
2018 Fondrie WE, Liang T, Oyler BL, Leung LM, Ernst RK, Strickland DK, Goodlett DR. Pathogen Identification Direct From Polymicrobial Specimens Using Membrane Glycolipids. Scientific Reports. 8: 15857. PMID 30367087 DOI: 10.1038/s41598-018-33681-8  0.84
2018 Mustapha MM, Li B, Pacey MP, Mettus RT, McElheny CL, Marshall CW, Ernst RK, Cooper VS, Doi Y. Phylogenomics of colistin-susceptible and resistant XDR Acinetobacter baumannii. The Journal of Antimicrobial Chemotherapy. PMID 30124845 DOI: 10.1093/jac/dky290  0.72
2018 Guillotte ML, Gillespie JJ, Chandler CE, Rahman MS, Ernst RK, Azad AF. Lipid A biosynthesis utilizes the late acyltransferase LpxJ for secondary fatty acid addition. Journal of Bacteriology. PMID 30012728 DOI: 10.1128/JB.00334-18  0.72
2018 Chandler CE, Harberts EM, Laemmermann T, Zeng Q, Opene BN, Germain RN, Jewell C, Scott AJ, Ernst RK. intradermal delivery of bacteria using microneedle arrays. Infection and Immunity. PMID 29986891 DOI: 10.1128/IAI.00406-18  0.84
2018 Khan MM, Ernst O, Sun J, Fraser IDC, Ernst RK, Goodlett DR, Nita-Lazar A. Mass spectrometry based structural analysis and systems immunoproteomics strategies for deciphering the host response to endotoxin. Journal of Molecular Biology. PMID 29949751 DOI: 10.1016/j.jmb.2018.06.032  0.84
2018 Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR. Correction to: Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate. Journal of the American Society For Mass Spectrometry. PMID 29687418 DOI: 10.1007/s13361-018-1960-8  0.84
2018 Sengyee S, Yoon SH, Paksanont S, Yimthin T, Wuthiekanun V, Limmathurotsakul D, West TE, Ernst RK, Chantratita N. Comprehensive analysis of clinical Burkholderia pseudomallei isolates demonstrates conservation of unique lipid A structure and TLR4-dependent innate immune activation. Plos Neglected Tropical Diseases. 12: e0006287. PMID 29474381 DOI: 10.1371/journal.pntd.0006287  0.72
2018 Oyler BL, Khan MM, Smith DF, Harberts EM, Kilgour DPA, Ernst RK, Cross AS, Goodlett DR. Top Down Tandem Mass Spectrometric Analysis of a Chemically Modified Rough-Type Lipopolysaccharide Vaccine Candidate. Journal of the American Society For Mass Spectrometry. PMID 29464544 DOI: 10.1007/s13361-018-1897-y  0.84
2017 Crawford MA, Fisher DJ, Leung LM, Lomonaco S, Lascols C, Cannatelli A, Giani T, Rossolini GM, Doi Y, Goodlett DR, Allard MW, Sharma SK, Khan E, Ernst RK, Hughes MA. CXC Chemokines Exhibit Bactericidal Activity against Multidrug-Resistant Gram-Negative Pathogens. Mbio. 8. PMID 29138303 DOI: 10.1128/mBio.01549-17  0.84
2017 Scott AJ, Post JM, Lerner R, Ellis SR, Lieberman J, Shirey KA, Heeren RMA, Bindila L, Ernst RK. Host-based lipid inflammation drives pathogenesis in Francisella infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 29109289 DOI: 10.1073/pnas.1712887114  0.84
2017 Zhang YF, Han K, Chandler CE, Tjaden B, Ernst RK, Lory S. Probing the sRNA regulatory landscape of P. aeruginosa: post-transcriptional control of determinants of pathogenicity and antibiotic susceptibility. Molecular Microbiology. PMID 28976035 DOI: 10.1111/mmi.13857  0.72
2017 Leung LM, Cooper VS, Rasko DA, Guo Q, Pacey MP, McElheny CL, Mettus RT, Yoon SH, Goodlett DR, Ernst RK, Doi Y. Structural modification of LPS in colistin-resistant, KPC-producing Klebsiella pneumoniae. The Journal of Antimicrobial Chemotherapy. PMID 28961916 DOI: 10.1093/jac/dkx234  0.84
2017 Barker WT, Martin SE, Chandler CE, Nguyen TV, Harris TL, Goodell C, Melander RJ, Doi Y, Ernst RK, Melander C. Small molecule adjuvants that suppress both chromosomal and mcr-1 encoded colistin-resistance and amplify colistin efficacy in polymyxin-susceptible bacteria. Bioorganic & Medicinal Chemistry. PMID 28958847 DOI: 10.1016/j.bmc.2017.08.055  0.72
2017 Mi W, Li Y, Yoon SH, Ernst RK, Walz T, Liao M. Structural basis of MsbA-mediated lipopolysaccharide transport. Nature. PMID 28869968 DOI: 10.1038/nature23649  0.72
2017 Chandler CE, Ernst RK. Bacterial lipids: powerful modifiers of the innate immune response. F1000research. 6. PMID 28868130 DOI: 10.12688/f1000research.11388.1  0.72
2017 Liu YY, Chandler CE, Leung LM, McElheny CL, Mettus RT, Shanks RM, Liu JH, Goodlett DR, Ernst RK, Doi Y. Structural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens. Antimicrobial Agents and Chemotherapy. PMID 28373195 DOI: 10.1128/AAC.00580-17  0.84
2017 Shaw DK, Wang X, Brown LJ, Chávez AS, Reif KE, Smith AA, Scott AJ, McClure EE, Boradia VM, Hammond HL, Sundberg EJ, Snyder GA, Liu L, DePonte K, Villar M, ... ... Ernst RK, et al. Infection-derived lipids elicit an immune deficiency circuit in arthropods. Nature Communications. 8: 14401. PMID 28195158 DOI: 10.1038/ncomms14401  0.84
2017 Scott AJ, Oyler BL, Goodlett DR, Ernst RK. Lipid A structural modifications in extreme conditions and identification of unique modifying enzymes to define the Toll-like receptor 4 structure-activity relationship. Biochimica Et Biophysica Acta. PMID 28108356 DOI: 10.1016/j.bbalip.2017.01.004  0.84
2016 Freiberg JA, Le Breton Y, Tran BQ, Scott AJ, Harro JM, Ernst RK, Goo YA, Mongodin EF, Goodlett DR, McIver KS, Shirtliff ME. Global Analysis and Comparison of the Transcriptomes and Proteomes of Group A Streptococcus Biofilms. Msystems. 1. PMID 27933318 DOI: 10.1128/mSystems.00149-16  0.84
2016 Kilgour DP, Hughes S, Kilgour SL, Mackay CL, Palmblad M, Tran BQ, Goo YA, Ernst RK, Clarke DJ, Goodlett DR. Autopiquer - a Robust and Reliable Peak Detection Algorithm for Mass Spectrometry. Journal of the American Society For Mass Spectrometry. PMID 27924495 DOI: 10.1007/s13361-016-1549-z  0.84
2016 Corey BW, Thompson MG, Hittle LE, Jacobs AC, Asafo-Adjei EA, Huggins W, Melander RJ, Melander C, Ernst RK, Zurawski DV. 1, 2, 4 -Triazolidine-3-thiones have specific activity against Acinetobacter baumannii amongst common nosocomial pathogens. Acs Infectious Diseases. PMID 27764938 DOI: 10.1021/acsinfecdis.6b00133  0.4
2016 Scott AJ, Flinders B, Cappell J, Liang T, Pelc RS, Tran B, Kilgour DP, Heeren RM, Goodlett DR, Ernst RK. Norharmane Matrix Enhances Detection of Endotoxin by MALDI-MS for Simultaneous Profiling of Pathogen, Host, and Vector Systems. Pathogens and Disease. PMID 27650574 DOI: 10.1093/femspd/ftw097  0.84
2016 Yoon SH, Liang T, Schneider T, Oyler BL, Chandler CE, Ernst RK, Yen GS, Huang Y, Nilsson E, Goodlett DR. Rapid Lipid A Structure Determination via Surface Acoustic Wave Nebulization and Hierarchical Tandem Mass Spectrometry Algorithm. Rapid Communications in Mass Spectrometry : Rcm. PMID 27582344 DOI: 10.1002/rcm.7728  0.84
2016 SenGupta S, Hittle LE, Ernst RK, Uriarte SM, Mitchell TC. A Pseudomonas aeruginosa hepta-acylated lipid A variant associated with cystic fibrosis selectively activates human neutrophils. Journal of Leukocyte Biology. PMID 27538572 DOI: 10.1189/jlb.4VMA0316-101R  0.4
2016 Li Y, Yoon SH, Wang X, Ernst RK, Goodlett DR. Structural Derivation of lipid A from Cronobacter sakazakii using Tandem Mass Spectrometry. Rapid Communications in Mass Spectrometry : Rcm. PMID 27502448 DOI: 10.1002/rcm.7712  0.4
2016 Brackett CM, Furlani RE, Anderson RG, Krishnamurthy A, Melander RJ, Moskowitz SM, Ernst RK, Melander C. Second Generation Modifiers of Colistin Resistance Show Enhanced Activity and Lower Inherent Toxicity. Tetrahedron. 72: 3549-3553. PMID 27429479 DOI: 10.1016/j.tet.2015.09.019  0.4
2016 Maldarelli GA, Piepenbrink KH, Scott AJ, Freiberg JA, Song Y, Achermann Y, Ernst RK, Shirtliff ME, Sundberg EJ, Donnenberg MS, von Rosenvinge EC. Type IV pili promote early biofilm formation by Clostridium difficile. Pathogens and Disease. PMID 27369898 DOI: 10.1093/femspd/ftw061  0.84
2016 Stephens MD, Hubble VB, Ernst RK, van Hoek ML, Melander RJ, Cavanagh J, Melander C. Potentiation of Francisella Resistance to Conventional Antibiotics through Small Molecule Adjuvants. Medchemcomm. 7: 128-131. PMID 26877862 DOI: 10.1039/C5MD00353A  0.4
2015 Renzi F, Zähringer U, Chandler CE, Ernst RK, Cornelis GR, Ittig SJ. Modification of the 1-phosphate group during biosynthesis of Capnocytophaga canimorsus lipid A. Infection and Immunity. PMID 26644381 DOI: 10.1128/IAI.01006-15  0.76
2015 Varga JJ, Barbier M, Mulet X, Bielecki P, Bartell JA, Owings JP, Martinez-Ramos I, Hittle LE, Davis MR, Damron FH, Liechti GW, Puchałka J, Dos Santos VA, Ernst RK, Papin JA, et al. Genotypic and phenotypic analyses of a Pseudomonas aeruginosa chronic bronchiectasis isolate reveal differences from cystic fibrosis and laboratory strains. Bmc Genomics. 16: 883. PMID 26519161 DOI: 10.1186/s12864-015-2069-0  0.76
2015 Chin CY, Gregg KA, Napier BA, Ernst RK, Weiss DS. A PmrB-regulated Deacetylase Required for Lipid A Modification and Polymyxin Resistance in Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. PMID 26459891 DOI: 10.1128/AAC.00515-15  0.76
2015 Hittle LE, Powell DA, Jones JW, Tofigh M, Goodlett DR, Moskowitz SM, Ernst RK. Site-specific activity of the acyltransferases HtrB1 and HtrB2 in Pseudomonas aeruginosa lipid A biosynthesis. Pathogens and Disease. PMID 26223882 DOI: 10.1093/femspd/ftv053  0.84
2015 Qureshi ZA, Hittle LE, O'Hara JA, Rivera JI, Syed A, Shields RK, Pasculle AW, Ernst RK, Doi Y. Colistin-resistant Acinetobacter baumannii: beyond carbapenem resistance. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 60: 1295-303. PMID 25632010 DOI: 10.1093/cid/civ048  0.76
2015 Reinhart AA, Powell DA, Nguyen AT, O'Neill M, Djapgne L, Wilks A, Ernst RK, Oglesby-Sherrouse AG. The prrF-encoded small regulatory RNAs are required for iron homeostasis and virulence of Pseudomonas aeruginosa. Infection and Immunity. 83: 863-75. PMID 25510881 DOI: 10.1128/IAI.02707-14  0.76
2014 Chirakul S, Bartpho T, Wongsurawat T, Taweechaisupapong S, Karoonutaisiri N, Talaat AM, Wongratanacheewin S, Ernst RK, Sermswan RW. Characterization of BPSS1521 (bprD), a regulator of Burkholderia pseudomallei virulence gene expression in the mouse model Plos One. 9. PMID 25111708 DOI: 10.1371/journal.pone.0104313  0.4
2014 Rolin O, Muse SJ, Safi C, Elahi S, Gerdts V, Hittle LE, Ernst RK, Harvill ET, Preston A. Enzymatic modification of lipid A by ArnT protects Bordetella bronchiseptica against cationic peptides and is required for transmission. Infection and Immunity. 82: 491-9. PMID 24478065 DOI: 10.1128/IAI.01260-12  0.76
2014 Richard K, Mann BJ, Stocker L, Barry EM, Qin A, Cole LE, Hurley MT, Ernst RK, Michalek SM, Stein DC, Deshong P, Vogel SN. Novel catanionic surfactant vesicle vaccines protect against Francisella tularensis LVS and confer significant partial protection against F. tularensis Schu S4 strain. Clinical and Vaccine Immunology : Cvi. 21: 212-26. PMID 24351755 DOI: 10.1128/CVI.00738-13  0.76
2014 Thaipisuttikul I, Hittle LE, Chandra R, Zangari D, Dixon CL, Garrett TA, Rasko DA, Dasgupta N, Moskowitz SM, Malmström L, Goodlett DR, Miller SI, Bishop RE, Ernst RK. A divergent Pseudomonas aeruginosa palmitoyltransferase essential for cystic fibrosis-specific lipid A. Molecular Microbiology. 91: 158-74. PMID 24283944 DOI: 10.1111/mmi.12451  0.76
2014 Scott AJ, Jones JW, Orschell CM, Macvittie TJ, Kane MA, Ernst RK. Mass spectrometry imaging enriches biomarker discovery approaches with Candidate mapping Health Physics. 106: 120-128. PMID 24276555 DOI: 10.1097/HP.0b013e3182a4ec2f  0.76
2014 Jones JW, Scott AJ, Tudor G, Xu PT, Jackson IL, Vujaskovic Z, Booth C, Macvittie TJ, Ernst RK, Kane MA. Identification and quantitation of biomarkers for radiation-induced injury via mass spectrometry Health Physics. 106: 106-119. PMID 24276554 DOI: 10.1097/HP.0b013e3182a4ed3b  0.76
2014 Harris TL, Worthington RJ, Hittle LE, Zurawski DV, Ernst RK, Melander C. Small molecule downregulation of PmrAB reverses lipid a modification and breaks colistin resistance Acs Chemical Biology. 9: 122-127. PMID 24131198 DOI: 10.1021/cb400490k  0.76
2013 Chantratita N, Tandhavanant S, Myers ND, Seal S, Arayawichanont A, Kliangsa-Ad A, Hittle LE, Ernst RK, Emond MJ, Wurfel MM, Day NP, Peacock SJ, West TE. Survey of innate immune responses to Burkholderia pseudomallei in human blood identifies a central role for lipopolysaccharide. Plos One. 8: e81617. PMID 24303060 DOI: 10.1371/journal.pone.0081617  0.76
2013 Li Y, Wang Z, Chen J, Ernst RK, Wang X. Influence of lipid A acylation pattern on membrane permeability and innate immune stimulation. Marine Drugs. 11: 3197-208. PMID 24065161 DOI: 10.3390/md11093197  0.64
2013 Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: implications in TLR4-independent endotoxic shock. Science (New York, N.Y.). 341: 1250-3. PMID 24031018 DOI: 10.1126/science.1240988  0.76
2013 Pelletier MR, Casella LG, Jones JW, Adams MD, Zurawski DV, Hazlett KR, Doi Y, Ernst RK. Unique structural modifications are present in the lipopolysaccharide from colistin-resistant strains of Acinetobacter baumannii. Antimicrobial Agents and Chemotherapy. 57: 4831-40. PMID 23877686 DOI: 10.1128/AAC.00865-13  0.76
2013 Nchoutmboube JA, Viktorova EG, Scott AJ, Ford LA, Pei Z, Watkins PA, Ernst RK, Belov GA. Increased long chain acyl-Coa synthetase activity and fatty acid import is linked to membrane synthesis for development of picornavirus replication organelles. Plos Pathogens. 9: e1003401. PMID 23762027 DOI: 10.1371/journal.ppat.1003401  0.76
2013 Shirey KA, Lai W, Scott AJ, Lipsky M, Mistry P, Pletneva LM, Karp CL, McAlees J, Gioannini TL, Weiss J, Chen WH, Ernst RK, Rossignol DP, Gusovsky F, Blanco JC, et al. The TLR4 antagonist Eritoran protects mice from lethal influenza infection. Nature. 497: 498-502. PMID 23636320 DOI: 10.1038/nature12118  0.76
2013 Rebeil R, Jarrett CO, Driver JD, Ernst RK, Oyston PC, Hinnebusch BJ. Induction of the Yersinia pestis PhoP-PhoQ regulatory system in the flea and its role in producing a transmissible infection. Journal of Bacteriology. 195: 1920-30. PMID 23435973 DOI: 10.1128/JB.02000-12  0.76
2013 O'Hara JA, Ambe LA, Casella LG, Townsend BM, Pelletier MR, Ernst RK, Shanks RM, Doi Y. Activities of vancomycin-containing regimens against colistin-resistant Acinetobacter baumannii clinical strains. Antimicrobial Agents and Chemotherapy. 57: 2103-8. PMID 23422916 DOI: 10.1128/AAC.02501-12  0.76
2012 Powell DA, Li Y, Ernst RK. Turning up Francisella pathogenesis: the LPS thermostat. Virulence. 3: 594-6. PMID 23154289 DOI: 10.4161/viru.22496  0.76
2012 Hajjar AM, Ernst RK, Fortuno ES, Brasfield AS, Yam CS, Newlon LA, Kollmann TR, Miller SI, Wilson CB. Humanized TLR4/MD-2 mice reveal LPS recognition differentially impacts susceptibility to Yersinia pestis and Salmonella enterica. Plos Pathogens. 8: e1002963. PMID 23071439 DOI: 10.1371/journal.ppat.1002963  0.76
2012 Yoon SH, Huang Y, Edgar JS, Ting YS, Heron SR, Kao Y, Li Y, Masselon CD, Ernst RK, Goodlett DR. Surface acoustic wave nebulization facilitating lipid mass spectrometric analysis. Analytical Chemistry. 84: 6530-7. PMID 22742654 DOI: 10.1021/ac300807p  0.76
2012 Li Y, Powell DA, Shaffer SA, Rasko DA, Pelletier MR, Leszyk JD, Scott AJ, Masoudi A, Goodlett DR, Wang X, Raetz CR, Ernst RK. LPS remodeling is an evolved survival strategy for bacteria. Proceedings of the National Academy of Sciences of the United States of America. 109: 8716-21. PMID 22586119 DOI: 10.1073/pnas.1202908109  0.76
2012 Kanistanon D, Powell DA, Hajjar AM, Pelletier MR, Cohen IE, Way SS, Skerrett SJ, Wang X, Raetz CR, Ernst RK. Role of Francisella lipid A phosphate modification in virulence and long-term protective immune responses. Infection and Immunity. 80: 943-51. PMID 22215738 DOI: 10.1128/IAI.06109-11  0.76
2011 Li Y, Wang X, Ernst RK. A rapid one-step method for the characterization of membrane lipid remodeling in Francisella using matrix-assisted laser desorption ionization time-of-flight tandem mass spectrometry. Rapid Communications in Mass Spectrometry : Rcm. 25: 2641-8. PMID 23657959 DOI: 10.1002/rcm.5168  0.64
2011 Simon R, Tennant SM, Wang JY, Schmidlein PJ, Lees A, Ernst RK, Pasetti MF, Galen JE, Levine MM. Salmonella enterica serovar enteritidis core O polysaccharide conjugated to H:g,m flagellin as a candidate vaccine for protection against invasive infection with S. enteritidis. Infection and Immunity. 79: 4240-9. PMID 21807909 DOI: 10.1128/IAI.05484-11  0.76
2011 Ting YS, Shaffer SA, Jones JW, Ng WV, Ernst RK, Goodlett DR. Automated lipid A structure assignment from hierarchical tandem mass spectrometry data. Journal of the American Society For Mass Spectrometry. 22: 856-66. PMID 21472520 DOI: 10.1007/s13361-010-0055-y  0.76
2011 Jassem AN, Zlosnik JE, Henry DA, Hancock RE, Ernst RK, Speert DP. In vitro susceptibility of Burkholderia vietnamiensis to aminoglycosides. Antimicrobial Agents and Chemotherapy. 55: 2256-64. PMID 21321142 DOI: 10.1128/AAC.01434-10  0.76
2010 Lai XH, Shirley RL, Crosa L, Kanistanon D, Tempel R, Ernst RK, Gallagher LA, Manoil C, Heffron F. Mutations of Francisella novicida that alter the mechanism of its phagocytosis by murine macrophages. Plos One. 5: e11857. PMID 20686600 DOI: 10.1371/journal.pone.0011857  0.76
2010 Moskowitz SM, Ernst RK. The role of Pseudomonas lipopolysaccharide in cystic fibrosis airway infection. Sub-Cellular Biochemistry. 53: 241-53. PMID 20593270 DOI: 10.1007/978-90-481-9078-2_11  0.76
2010 Jones JW, Cohen IE, Tureĉek F, Goodlett DR, Ernst RK. Comprehensive structure characterization of lipid A extracted from Yersinia pestis for determination of its phosphorylation configuration. Journal of the American Society For Mass Spectrometry. 21: 785-99. PMID 20185334 DOI: 10.1016/j.jasms.2010.01.008  0.76
2009 Pilonieta MC, Erickson KD, Ernst RK, Detweiler CS. A protein important for antimicrobial peptide resistance, YdeI/OmdA, is in the periplasm and interacts with OmpD/NmpC. Journal of Bacteriology. 191: 7243-52. PMID 19767429 DOI: 10.1128/JB.00688-09  0.76
2009 Coats SR, Jones JW, Do CT, Braham PH, Bainbridge BW, To TT, Goodlett DR, Ernst RK, Darveau RP. Human Toll-like receptor 4 responses to P. gingivalis are regulated by lipid A 1- and 4'-phosphatase activities. Cellular Microbiology. 11: 1587-99. PMID 19552698 DOI: 10.1111/j.1462-5822.2009.01349.x  0.76
2009 Berezow AB, Ernst RK, Coats SR, Braham PH, Karimi-Naser LM, Darveau RP. The structurally similar, penta-acylated lipopolysaccharides of Porphyromonas gingivalis and Bacteroides elicit strikingly different innate immune responses. Microbial Pathogenesis. 47: 68-77. PMID 19460428 DOI: 10.1016/j.micpath.2009.04.015  0.76
2009 Kalhorn TF, Kiavand A, Cohen IE, Nelson AK, Ernst RK. A sensitive liquid chromatography/mass spectrometry-based assay for quantitation of amino-containing moieties in lipid A. Rapid Communications in Mass Spectrometry : Rcm. 23: 433-42. PMID 19130491 DOI: 10.1002/rcm.3900  0.76
2008 Jones JW, Shaffer SA, Ernst RK, Goodlett DR, Turecek F. Determination of pyrophosphorylated forms of lipid A in Gram-negative bacteria using a multivaried mass spectrometric approach. Proceedings of the National Academy of Sciences of the United States of America. 105: 12742-7. PMID 18753624 DOI: 10.1073/pnas.0800445105  0.76
2008 West TE, Ernst RK, Jansson-Hutson MJ, Skerrett SJ. Activation of Toll-like receptors by Burkholderia pseudomallei. Bmc Immunology. 9: 46. PMID 18691413 DOI: 10.1186/1471-2172-9-46  0.48
2008 Bainbridge BW, Karimi-Naser L, Reife R, Blethen F, Ernst RK, Darveau RP. Acyl chain specificity of the acyltransferases LpxA and LpxD and substrate availability contribute to lipid A fatty acid heterogeneity in Porphyromonas gingivalis. Journal of Bacteriology. 190: 4549-58. PMID 18456814 DOI: 10.1128/JB.00234-08  0.76
2008 Kanistanon D, Hajjar AM, Pelletier MR, Gallagher LA, Kalhorn T, Shaffer SA, Goodlett DR, Rohmer L, Brittnacher MJ, Skerrett SJ, Ernst RK. A Francisella mutant in lipid A carbohydrate modification elicits protective immunity. Plos Pathogens. 4: e24. PMID 18266468 DOI: 10.1371/journal.ppat.0040024  0.76
2007 Ernst RK, Moskowitz SM, Emerson JC, Kraig GM, Adams KN, Harvey MD, Ramsey B, Speert DP, Burns JL, Miller SI. Unique lipid a modifications in Pseudomonas aeruginosa isolated from the airways of patients with cystic fibrosis. The Journal of Infectious Diseases. 196: 1088-92. PMID 17763333 DOI: 10.1086/521367  0.76
2007 Rohmer L, Fong C, Abmayr S, Wasnick M, Larson Freeman TJ, Radey M, Guina T, Svensson K, Hayden HS, Jacobs M, Gallagher LA, Manoil C, Ernst RK, Drees B, Buckley D, et al. Comparison of Francisella tularensis genomes reveals evolutionary events associated with the emergence of human pathogenic strains. Genome Biology. 8: R102. PMID 17550600 DOI: 10.1186/gb-2007-8-6-r102  0.76
2007 D'Argenio DA, Wu M, Hoffman LR, Kulasekara HD, Déziel E, Smith EE, Nguyen H, Ernst RK, Larson Freeman TJ, Spencer DH, Brittnacher M, Hayden HS, Selgrade S, Klausen M, Goodlett DR, et al. Growth phenotypes of Pseudomonas aeruginosa lasR mutants adapted to the airways of cystic fibrosis patients. Molecular Microbiology. 64: 512-33. PMID 17493132 DOI: 10.1111/j.1365-2958.2007.05678.x  0.76
2007 Mohapatra NP, Soni S, Bell BL, Warren R, Ernst RK, Muszynski A, Carlson RW, Gunn JS. Identification of an orphan response regulator required for the virulence of Francisella spp. and transcription of pathogenicity island genes. Infection and Immunity. 75: 3305-14. PMID 17452468 DOI: 10.1128/IAI.00351-07  0.76
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