Keith S Learn - Publications

Affiliations: 
1979-1983 Drexel University, Philadelphia, PA, United States 

9/24 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Ott GR, Cheng M, Learn KS, Wagner J, Gingrich DE, Lisko JG, Curry M, Mesaros EF, Ghose AK, Quail MR, Wan W, Lu L, Dobrzanski P, Albom MS, Angeles TS, et al. Discovery of Clinical Candidate CEP-37440, a Selective Inhibitor of Focal Adhesion Kinase (FAK) and Anaplastic Lymphoma Kinase (ALK). Journal of Medicinal Chemistry. PMID 27527804 DOI: 10.1021/acs.jmedchem.6b00487  1
2012 Learn KS, Wagner JC, Albom MS, Angeles TS, Huang Z, Ghose AK, Wan W, Cheng M, Dorsey BD, Ott GR. Design of 7-amino-6-chloro-3H-imidazo[4,5-b]pyridine scaffold from 5-chloro-2,4-diaminopyrimidine pharmacophore: Identification of potent inhibitors of anaplastic lymphoma kinase Medchemcomm. 3: 1138-1142. DOI: 10.1039/c2md20061a  1
1990 Galemmo RA, Johnson WH, Learn KS, Lee TD, Huang FC, Campbell HF, Youssefyeh R, O'Rourke SV, Schuessler G, Sweeney DM. The development of a novel series of (quinolin-2-ylmethoxy)phenyl-containing compounds as high-affinity leukotriene receptor antagonists. 3. Structural variation of the acidic side chain to give antagonists of enhanced potency. Journal of Medicinal Chemistry. 33: 2828-41. PMID 2170649 DOI: 10.1021/JM00172A024  1
1986 Palmer JT, Learn KS, Fuchs PL. Synthesis and facile one-pot aldol/elimination/diels-alder reaction of β-keto-Z-dienylamides as cytochalasin C intermediates Synthetic Communications. 16: 1315-1333. DOI: 10.1080/00397918608056379  1
1986 Hensel MJ, Palmer JT, Learn KS, Fuchs PL. An intramolecular diels-alder reaction of A Z-diene. Generation of the chiral isoindolone nucleus of Cytochalasin C Synthetic Communications. 16: 1297-1314. DOI: 10.1080/00397918608056378  1
1984 Hutchins RO, Learn K, Nazer B, Pytlewski D, Pelter A. Amine boranes as selective reducing and hydroborating agents. A review Organic Preparations and Procedures International. 16: 335-372. DOI: 10.1002/Chin.198518362  1
1984 Hutchins RO, Learn K, El-Telbany F, Stercho YP. Aminoborohydrides as reducing agents. 1. Sodium (dimethylamino)- and (tert-butylamino)borohydrides as selective reducing agents Journal of Organic Chemistry. 49: 2438-2443. DOI: 10.1002/Chin.198450110  1
1982 Hutchins RO, Learn K. Regio- and stereoselective reductive replacement of allylic oxygen, sulfur, and selenium functional groups by hydride via catalytic activation by palladium(0) complexes Journal of Organic Chemistry. 47: 4380-4382. DOI: 10.1021/Jo00143A054  1
1980 Hutchins RO, Learn K, Fulton RP. Reductive displacement of allylic acetates by hydride transfer via catalytic activation by palladium(0) complexes Tetrahedron Letters. 21: 27-30. DOI: 10.1016/S0040-4039(00)93615-3  1
Low-probability matches
2002 Tripathy R, Learn KS, Reddy DR, Iqbal M, Singh J, Mallamo JP. Construction of a kinase inhibitor library via parallel synthesis Tetrahedron Letters. 43: 217-220. DOI: 10.1016/S0040-4039(01)02140-2  0.01
1995 Gleason MM, Rojas CJ, Learn KS, Perrone MH, Bilder GE. Characterization and inhibition of 15-lipoxygenase in human monocytes: comparison with soybean 15-lipoxygenase. The American Journal of Physiology. 268: C1301-7. PMID 7762624 DOI: 10.1152/AJPCELL.1995.268.5.C1301  0.01
1991 Huang FC, Galemmo RA, Poli GB, Learn KS, Morrissette MM, Johnson WH, Dankulich WP, Campbell HF, Carnathan GW, VanInwegen RG. Development of a novel series of (2-quinolinylmethoxy)phenyl-containing compounds as high-affinity leukotriene D4 receptor antagonists. 4. Addition of chromone moiety enhances leukotriene D4 receptor binding affinity. Journal of Medicinal Chemistry. 34: 1704-7. PMID 1851845 DOI: 10.1021/JM00109A025  0.01
1989 LEE VJ, CURRAN WV, FIELDS TF, LEARN K. ChemInform Abstract: 1,2,3-Thiadiazoles. Part 1. Synthesis of Sodium (or Potassium) 1,2,3-Thiadiazole-4-thiolates via Thiocarbazonate Esters and N-Acylthiohydrazonate Esters. Cheminform. 20. DOI: 10.1002/CHIN.198933154  0.01
1988 Paquette LA, Learn KS, Romine JL, Lin HS. Molecular recognition during 1,2-addition of chiral vinyl organometallics to chiral .beta.,.gamma.-unsaturated ketones. Case studies of three 7,7-disubstituted 2-norbornenones. Part 5 Journal of the American Chemical Society. 110: 879-890. DOI: 10.1021/Ja00211A031  0.01
1988 Lee VJ, Curran WV, Fields TF, Learn K. 1,2,3-thiadiazoles. I. Synthesis of sodium (or potassium) 1,2,3-thiadiazole-4-thiolatesviathiocarbazonate esters andN-acylthiohydrazonate esters Journal of Heterocyclic Chemistry. 25: 1873-1891. DOI: 10.1002/JHET.5570250651  0.01
1988 PAQUETTE LA, LEARN KS, ROMINE JL, LIN H. ChemInform Abstract: Molecular Recognition During 1,2-Addition of Chiral Vinyl Organometallics to Chiral β,γ-Unsaturated Ketones. Case Studies of Three 7,7-Disubstituted 2-Norbornenones. Part 5. Cheminform. 19. DOI: 10.1002/CHIN.198822102  0.01
1988 PAQUETTE LA, LEARN KS, ROMINE JL. ChemInform Abstract: Double Diastereoselection Operative During π-Facially Selective Addition of Chiral 1-Cyclopentenyllithium Reagents to (7R*)-7-Methyl-7-vinylbicyclo(3.2.0)hept-2-en-6-one. Cheminform. 19. DOI: 10.1002/CHIN.198810149  0.01
1987 Paquette LA, Learn KS, Romine JL. Double Diastereoselection Operative During π-Facially Selective Addition of Chiral 1-Cyclopentenyllithium Reagents to (7R)-7-Methyl-7-Vinylbicyclo[3.2.0]Hept-2-En-6-One Synthetic Communications. 17: 369-375. DOI: 10.1080/00397918708063913  0.01
1987 Paquette LA, Learn KS, Romine JL. Doubly diastereoselective nucleophilic additions to a bicyclic β,γ-unsaturated ketone possessing a conformationally mobile double bond Tetrahedron. 43: 4989-5002. DOI: 10.1016/S0040-4020(01)87678-X  0.01
1987 PAQUETTE LA, LEARN KS. ChemInform Abstract: π-Facially Controlled Nucleophilic Additions of Chiral Vinylorganometallics to Chiral β,γ-Unsaturated Ketones. Part 1. Double Diastereoselection Studies Involving 7,7-Dimethoxy-5-norbornen-2-one. Cheminform. 18. DOI: 10.1002/CHIN.198715081  0.01
1987 PALMER JT, LEARN KS, FUCHS PL. ChemInform Abstract: Cytolasin Report Studies. Part 8. Synthesis and Facile One-Pot Aldol/ Elimination/Diels-Alder Reaction of β-Keto-Z-dienylamides as Cytochalasin C Intermediates. Cheminform. 18. DOI: 10.1002/chin.198710216  0.01
1987 HENSEL MJ, PALMER JT, LEARN KS, FUCHS PL. ChemInform Abstract: Cytolasin Report Studies. Part 7. An Intramolecular Diels-Alder Reaction of a Z-Diene. Generation of the Chiral Isoindolonone Nucleus of Cytochalsasin C. Cheminform. 18. DOI: 10.1002/chin.198710215  0.01
1986 Paquette LA, Learn KS. .pi.-Facially controlled nucleophilic additions of chiral vinylorganometallics to chiral .beta.,.gamma.-unsaturated ketones. 1. Double diastereoselection studies involving 7,7-dimethoxy-5-norbornen-2-one Journal of the American Chemical Society. 108: 7873-7875. PMID 22283323 DOI: 10.1021/Ja00284A085  0.01
1984 Hutchins RO, Learn K, Nazer B, Pytlewski D, Pelter A. AMINE BORANES AS SELECTIVE REDUCING AND HYDROBORATING AGENTS. A REVIEW Organic Preparations and Procedures International. 16: 335-372. DOI: 10.1080/00304948409457891  0.01
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