Shilong Zheng - Publications

Affiliations: 
2007 Georgia State University, Atlanta, GA, United States 

47 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Chen G, Patanapongpibul M, Jiang Z, Zhang Q, Zheng S, Wang G, White JD, Chen QH. Synthesis and antiproliferative evaluation of new zampanolide mimics. Organic & Biomolecular Chemistry. PMID 30924817 DOI: 10.1039/c9ob00556k  0.52
2019 Rajaram P, Jiang Z, Chen G, Rivera A, Phasakda A, Zhang Q, Zheng S, Wang G, Chen QH. Nitrogen-containing derivatives of O-tetramethylquercetin: Synthesis and biological profiles in prostate cancer cell models. Bioorganic Chemistry. 87: 227-239. PMID 30904813 DOI: 10.1016/j.bioorg.2019.03.047  0.52
2019 Yang Z, Zhong Q, Zheng S, Wang G, He L. Synthesis and Antitumor Activity of a Series of Novel 1-Oxa-4-azaspiro[4,5]deca-6,9-diene-3,8-dione Derivatives. Molecules (Basel, Switzerland). 24. PMID 30866506 DOI: 10.3390/molecules24050936  0.52
2018 Vue B, Zhang S, Vignau A, Chen G, Zhang X, Diaz W, Zhang Q, Zheng S, Wang G, Chen QH. -Aminoalkyl--Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells. Molecules (Basel, Switzerland). 23. PMID 30501133 DOI: 10.3390/molecules23123142  0.52
2018 Li X, Zhang C, Guo S, Rajaram P, Lee M, Chen G, Fong R, Gonzalez A, Zhang Q, Zheng S, Wang G, Chen QH. Structure-activity relationship and pharmacokinetic studies of 3-O-substitutedflavonols as anti-prostate cancer agents. European Journal of Medicinal Chemistry. 157: 978-993. PMID 30165345 DOI: 10.1016/j.ejmech.2018.08.047  0.52
2018 Patanapongpibul M, Zhang C, Chen G, Guo S, Zhang Q, Zheng S, Wang G, Chen QH. Optimization of diarylpentadienones as chemotherapeutics for prostate cancer. Bioorganic & Medicinal Chemistry. PMID 30121214 DOI: 10.1016/j.bmc.2018.08.018  0.52
2018 Wu K, Yu X, Huang Z, Zhu D, Yi X, Wu YL, Hao Q, Kemp KT, Elshimali Y, Iyer R, Nguyen KT, Zheng S, Chen G, Chen QH, Wang G, et al. Targeting of PP2Cδ by a small molecule C23 inhibits high glucose-induced breast cancer progression in vivo. Antioxidants & Redox Signaling. PMID 29808718 DOI: 10.1089/ars.2017.7486  0.52
2018 Chen G, Wang R, Vue B, Patanapongpibul M, Zhang Q, Zheng S, Wang G, White JD, Chen QH. Optimized synthesis and antiproliferative activity of desTHPdactylolides. Bioorganic & Medicinal Chemistry. PMID 29784275 DOI: 10.1016/j.bmc.2018.05.026  0.52
2018 Guo S, Zhang C, Bratton M, Mottamal M, Liu J, Ma P, Zheng S, Zhong Q, Yang L, Wiese TE, Wu Y, Ellis MJ, Matossian M, Burow ME, Miele L, et al. ZB716, a steroidal selective estrogen receptor degrader (SERD), is orally efficacious in blocking tumor growth in mouse xenograft models. Oncotarget. 9: 6924-6937. PMID 29467940 DOI: 10.18632/oncotarget.24023  0.52
2018 Zheng S, Guo S, Zhong Q, Zhang C, Liu J, Yang L, Zhang Q, Wang G. Biocompatible Boron-Containing Prodrugs of Belinostat for the Potential Treatment of Solid Tumors. Acs Medicinal Chemistry Letters. 9: 149-154. PMID 29456804 DOI: 10.1021/acsmedchemlett.7b00504  0.52
2017 Gu L, Wang P, Zhong Q, Deng Y, Xie J, Liu F, Xiao F, Zheng S, Chen Y, Wang G, He L. Copper salt-catalyzed formation of a novel series of triazole-spirodienone conjugates with potent anticancer activity. Rsc Advances. 7: 9412-9416. PMID 30740218 DOI: 10.1039/C6RA24764D  0.52
2017 Zhang C, Guo S, Yang L, Liu J, Zheng S, Zhong Q, Zhang Q, Wang G. Metabolism, pharmacokinetics, and bioavailability of ZB716, a Steroidal Selective Estrogen Receptor Downregulator (SERD). Oncotarget. 8: 103874-103889. PMID 29262607 DOI: 10.18632/oncotarget.21808  0.52
2017 Li X, Lee M, Chen G, Zhang Q, Zheng S, Wang G, Chen QH. 3-O-Substituted-3',4',5'-trimethoxyflavonols: Synthesis and cell-based evaluation as anti-prostate cancer agents. Bioorganic & Medicinal Chemistry. PMID 28760528 DOI: 10.1016/j.bmc.2017.07.022  0.52
2017 Vue B, Zhang X, Lee T, Nair N, Zhang S, Chen G, Zhang Q, Zheng S, Wang G, Chen QH. 5- or/and 20-O-alkyl-2,3-dehydrosilybins: Synthesis and biological profiles on prostate cancer cell models. Bioorganic & Medicinal Chemistry. PMID 28756013 DOI: 10.1016/j.bmc.2017.07.035  0.52
2017 Zhang X, Guo S, Chen C, Perez GR, Zhang C, Patanapongpibul M, Subrahmanyam N, Wang R, Keith J, Chen G, Dong Y, Zhang Q, Zhong Q, Zheng S, Wang G, et al. Asymmetric 1,5-diarylpenta-1,4-dien-3-ones: Antiproliferative activity in prostate epithelial cell models and pharmacokinetic studies. European Journal of Medicinal Chemistry. 137: 263-279. PMID 28601720 DOI: 10.1016/j.ejmech.2017.05.062  0.52
2017 Wang R, Zhang X, Chen C, Chen G, Sarabia C, Zhang Q, Zheng S, Wang G, Chen QH. Structure-activity relationship studies of 1,7-diheteroarylhepta-1,4,6-trien-3-ones with two different terminal rings in prostate epithelial cell models. European Journal of Medicinal Chemistry. 133: 208-226. PMID 28388523 DOI: 10.1016/j.ejmech.2017.03.067  0.52
2017 Liu J, Zheng S, Guo S, Zhang C, Zhong Q, Zhang Q, Ma P, Skripnikova EV, Bratton MR, Wiese TE, Wang G. Rational Design of a Boron-Modified Triphenylethylene (GLL398) as an Oral Selective Estrogen Receptor Downregulator. Acs Medicinal Chemistry Letters. 8: 102-106. PMID 28105283 DOI: 10.1021/acsmedchemlett.6b00410  0.52
2017 Komati R, Spadoni D, Zheng S, Sridhar J, Riley KE, Wang G. Ligands of Therapeutic Utility for the Liver X Receptors. Molecules (Basel, Switzerland). 22. PMID 28067791 DOI: 10.3390/molecules22010088  0.52
2016 Zhang X, Wang R, Perez GR, Chen G, Zhang Q, Zheng S, Wang G, Chen QH. Design, synthesis, and biological evaluation of 1,9-diheteroarylnona-1,3,6,8-tetraen-5-ones as a new class of anti-prostate cancer agents. Bioorganic & Medicinal Chemistry. PMID 27543391 DOI: 10.1016/j.bmc.2016.08.006  0.44
2016 Liu J, Zheng S, Akerstrom VL, Yuan C, Ma Y, Zhong Q, Zhang C, Zhang Q, Guo S, Ma P, Skripnikova EV, Bratton MR, Pannuti A, Miele L, Wiese TE, et al. Fulvestrant-3 Boronic Acid (ZB716): An Orally Bioavailable Selective Estrogen Receptor Downregulator (SERD). Journal of Medicinal Chemistry. PMID 27529700 DOI: 10.1021/acs.jmedchem.6b00753  0.44
2016 Li X, Chen G, Zhang X, Zhang Q, Zheng S, Wang G, Chen QH. A new class of flavonol-based anti-prostate cancer agents: Design, synthesis, and evaluation in cell models. Bioorganic & Medicinal Chemistry Letters. PMID 27476422 DOI: 10.1016/j.bmcl.2016.07.050  0.52
2016 Li Y, Cao TT, Guo S, Zhong Q, Li CH, Li Y, Dong L, Zheng S, Wang G, Yin SF. Discovery of Novel Allopurinol Derivatives with Anticancer Activity and Attenuated Xanthine Oxidase Inhibition. Molecules (Basel, Switzerland). 21. PMID 27331805 DOI: 10.3390/molecules21060771  0.44
2016 Zhang S, Vue B, Huang M, Zhang X, Lee T, Chen G, Zhang Q, Zheng S, Wang G, Chen QH. 3-O-Alkyl-2,3-dehydrosilibinins: Two synthetic approaches and in vitro effects toward prostate cancer cells. Bioorganic & Medicinal Chemistry Letters. PMID 27261177 DOI: 10.1016/j.bmcl.2016.05.069  0.52
2016 Wang R, Zhang X, Chen C, Chen G, Zhong Q, Zhang Q, Zheng S, Wang G, Chen QH. Synthesis and evaluation of 1,7-diheteroarylhepta-1,4,6-trien-3-ones as curcumin-based anticancer agents. European Journal of Medicinal Chemistry. 110: 164-180. PMID 26827161 DOI: 10.1016/j.ejmech.2016.01.017  0.52
2015 Vue B, Zhang S, Zhang X, Parisis K, Zhang Q, Zheng S, Wang G, Chen QH. Silibinin derivatives as anti-prostate cancer agents: Synthesis and cell-based evaluations. European Journal of Medicinal Chemistry. 109: 36-46. PMID 26748997 DOI: 10.1016/j.ejmech.2015.12.041  0.52
2015 Zheng S, Liu J, Wu Y, Huang TL, Wang G. Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics. Future Medicinal Chemistry. 7: 2485-505. PMID 26670195 DOI: 10.4155/fmc.15.159  0.52
2015 Zhong Q, Zhang C, Zhang Q, Miele L, Zheng S, Wang G. Boronic prodrug of 4-hydroxytamoxifen is more efficacious than tamoxifen with enhanced bioavailability independent of CYP2D6 status. Bmc Cancer. 15: 625. PMID 26354796 DOI: 10.1186/s12885-015-1621-2  0.44
2015 Zhao LM, Ma FY, Jin HS, Zheng S, Zhong Q, Wang G. Design and synthesis of novel hydroxyanthraquinone nitrogen mustard derivatives as potential anticancer agents via a bioisostere approach. European Journal of Medicinal Chemistry. 102: 303-9. PMID 26291039 DOI: 10.1016/j.ejmech.2015.08.006  0.52
2015 Liu J, Pham PT, Skripnikova EV, Zheng S, Lovings LJ, Wang Y, Goyal N, Bellow SM, Mensah LM, Chatters AJ, Bratton MR, Wiese TE, Zhao M, Wang G, Foroozesh M. A Ligand-Based Drug Design, Discovery of 4-Trifluoromethyl-7,8-Pyranocoumarin as a Selective Inhibitor of Human Cytochrome P450 1A2. Journal of Medicinal Chemistry. PMID 26222195 DOI: 10.1021/acs.jmedchem.5b00494  0.52
2015 Zhang C, Zhong Q, Zhang Q, Zheng S, Miele L, Wang G. Boronic prodrug of endoxifen as an effective hormone therapy for breast cancer. Breast Cancer Research and Treatment. 152: 283-91. PMID 26071758 DOI: 10.1007/s10549-015-3461-9  0.44
2015 Xiong P, Wang R, Zhang X, DeLa Torre E, Leon F, Zhang Q, Zheng S, Wang G, Chen QH. Design, Synthesis, and Evaluation of Genistein Analogues as Anti-Cancer Agents. Anti-Cancer Agents in Medicinal Chemistry. PMID 25991428  0.52
2015 Wang R, Chen C, Zhang X, Zhang C, Zhong Q, Chen G, Zhang Q, Zheng S, Wang G, Chen QH. Structure-Activity Relationship and Pharmacokinetic Studies of 1,5-Diheteroarylpenta-1,4-dien-3-ones: A Class of Promising Curcumin-Based Anticancer Agents. Journal of Medicinal Chemistry. 58: 4713-26. PMID 25961334 DOI: 10.1021/acs.jmedchem.5b00470  0.52
2015 Mottamal M, Zheng S, Huang TL, Wang G. Histone deacetylase inhibitors in clinical studies as templates for new anticancer agents. Molecules (Basel, Switzerland). 20: 3898-941. PMID 25738536 DOI: 10.3390/molecules20033898  0.52
2014 Strong AL, Ohlstein JF, Jiang Q, Zhang Q, Zheng S, Boue SM, Elliott S, Gimble JM, Burow ME, Wang G, Bunnell BA. Novel daidzein analogs enhance osteogenic activity of bone marrow-derived mesenchymal stem cells and adipose-derived stromal/stem cells through estrogen receptor dependent and independent mechanisms. Stem Cell Research & Therapy. 5: 105. PMID 25168698 DOI: 10.1186/scrt493  0.44
2014 Zheng S, Zhong Q, Xi Y, Mottamal M, Zhang Q, Schroeder RL, Sridhar J, He L, McFerrin H, Wang G. Modification and biological evaluation of thiazole derivatives as novel inhibitors of metastatic cancer cell migration and invasion. Journal of Medicinal Chemistry. 57: 6653-67. PMID 25007006 DOI: 10.1021/jm500724x  0.44
2014 Strong AL, Jiang Q, Zhang Q, Zheng S, Boue SM, Elliott S, Burow ME, Bunnell BA, Wang G. Design, synthesis, and osteogenic activity of daidzein analogs on human mesenchymal stem cells. Acs Medicinal Chemistry Letters. 5: 143-8. PMID 24900787 DOI: 10.1021/ml400397k  0.44
2014 Zheng S, Zhong Q, Mottamal M, Zhang Q, Zhang C, Lemelle E, McFerrin H, Wang G. Design, synthesis, and biological evaluation of novel pyridine-bridged analogues of combretastatin-A4 as anticancer agents. Journal of Medicinal Chemistry. 57: 3369-81. PMID 24669888 DOI: 10.1021/jm500002k  0.52
2014 Samaan N, Zhong Q, Fernandez J, Chen G, Hussain AM, Zheng S, Wang G, Chen QH. Design, synthesis, and evaluation of novel heteroaromatic analogs of curcumin as anti-cancer agents. European Journal of Medicinal Chemistry. 75: 123-31. PMID 24531225 DOI: 10.1016/j.ejmech.2014.01.041  0.44
2013 Jiang Q, Zheng S, Wang G. Development of new estrogen receptor-targeting therapeutic agents for tamoxifen-resistant breast cancer. Future Medicinal Chemistry. 5: 1023-35. PMID 23734685 DOI: 10.4155/fmc.13.63  0.52
2013 Zheng S, Zhong Q, Jiang Q, Mottamal M, Zhang Q, Zhu N, Burow ME, Worthylake RA, Wang G. Discovery of a Series of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion. Acs Medicinal Chemistry Letters. 4: 191-196. PMID 23526571 DOI: 10.1021/ml300322n  0.52
2012 Jiang Q, Zhong Q, Zhang Q, Zheng S, Wang G. Boron-Based 4-Hydroxytamoxifen Bioisosteres for Treatment of de Novo Tamoxifen Resistant Breast Cancer. Acs Medicinal Chemistry Letters. 3: 392-396. PMID 23864928 DOI: 10.1021/ml3000287  0.52
2011 Cheng Y, Dai C, Peng H, Zheng S, Jin S, Wang B. Design, synthesis, and polymerase-catalyzed incorporation of click-modified boronic acid-TTP analogues. Chemistry, An Asian Journal. 6: 2747-52. PMID 21887745 DOI: 10.1002/asia.201100229  0.88
2010 Jiang Q, Payton-Stewart F, Elliott S, Driver J, Rhodes LV, Zhang Q, Zheng S, Bhatnagar D, Boue SM, Collins-Burow BM, Sridhar J, Stevens C, McLachlan JA, Wiese TE, Burow ME, et al. Effects of 7-O substitutions on estrogenic and anti-estrogenic activities of daidzein analogues in MCF-7 breast cancer cells. Journal of Medicinal Chemistry. 53: 6153-63. PMID 20669983 DOI: 10.1021/jm100610w  0.52
2010 King-Keller S, Li M, Smith A, Zheng S, Kaur G, Yang X, Wang B, Docampo R. Chemical validation of phosphodiesterase C as a chemotherapeutic target in Trypanosoma cruzi, the etiological agent of Chagas' disease. Antimicrobial Agents and Chemotherapy. 54: 3738-45. PMID 20625148 DOI: 10.1128/AAC.00313-10  0.52
2009 Kamio M, Ko KC, Zheng S, Wang B, Collins SL, Gadda G, Tai PC, Derby CD. The chemistry of escapin: identification and quantification of the components in the complex mixture generated by an L-amino acid oxidase in the defensive secretion of the sea snail Aplysia californica. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 1597-603. PMID 19130530 DOI: 10.1002/chem.200801696  0.52
2008 Du L, Li M, Zheng S, Wang B. Rational Design of a Fluorescent Hydrogen Peroxide Probe Based on the Umbelliferone Fluorophore. Tetrahedron Letters. 49: 3045-3048. PMID 19081820 DOI: 10.1016/j.tetlet.2008.03.063  0.88
2008 Zheng S, Kaur G, Wang H, Li M, Macnaughtan M, Yang X, Reid S, Prestegard J, Wang B, Ke H. Design, synthesis, and structure - Activity relationship, molecular modeling, and NMR studies of a series of phenyl alkyl ketones as highly potent and selective phosphodiesterase-4 inhibitors Journal of Medicinal Chemistry. 51: 7673-7688. PMID 19049349 DOI: 10.1021/jm701635j  0.52
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