Xin-Yuan Fu - Publications

Affiliations: 
Microbiology and Immunology Indiana University & Yale University 
Area:
Molecular biology and Signaling mechanisms
Website:
http://micro.medicine.iu.edu/faculty/primary-faculty/xin-yuan-fu-ph-d/

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Mu T, Xu L, Zhong Y, Liu X, Zhao Z, Huang C, Lan X, Lufei C, Zhou Y, Su Y, Xu L, Jiang M, Zhou H, Lin X, Wu L, ... ... Fu XY, et al. Embryonic liver developmental trajectory revealed by single-cell RNA sequencing in the Foxa2 mouse. Communications Biology. 3: 642. PMID 33144666 DOI: 10.1038/s42003-020-01364-8  0.555
2020 Ma Z, Sheng N, Liu X, Su Y, Zhou Y, Sun Y, Mu T, Xu J, Feng J, Zhao Z, Fu XY. Knockout of Stat5 in T cells ameliorates high cholesterol and high fat diet-induced hypercholesterolemia by influencing cholesterol metabolism in the liver. Cellular & Molecular Immunology. PMID 32139883 DOI: 10.1038/S41423-020-0389-8  0.517
2018 Wong YQ, Xu H, Wu Q, Liu X, Lufei C, Xu XQ, Fu XY. STAT3-Inducible Mouse ESCs: A Model to Study the Role of STAT3 in ESC Maintenance and Lineage Differentiation. Stem Cells International. 2018: 8632950. PMID 30254684 DOI: 10.1155/2018/8632950  0.332
2018 Gu H, Do DV, Liu X, Xu L, Su Y, Nah JM, Wong Y, Li Y, Sheng N, Tilaye GA, Yang H, Guo H, Yan J, Fu XY. The STAT3 Target Mettl8 Regulates Mouse ESC Differentiation via Inhibiting the JNK Pathway. Stem Cell Reports. PMID 29706498 DOI: 10.1016/J.Stemcr.2018.03.022  0.663
2015 Kumar A, Lualdi M, Lyozin GT, Sharma P, Loncarek J, Fu XY, Kuehn MR. Nodal signaling from the visceral endoderm is required to maintain Nodal gene expression in the epiblast and drive DVE/AVE migration. Developmental Biology. 400: 1-9. PMID 25536399 DOI: 10.1016/j.ydbio.2014.12.016  0.336
2014 Ow JR, Ma H, Jean A, Goh Z, Lee YH, Chong YM, Soong R, Fu XY, Yang H, Wu Q. Patz1 regulates embryonic stem cell identity. Stem Cells and Development. 23: 1062-73. PMID 24380431 DOI: 10.1089/scd.2013.0430  0.391
2013 Do DV, Ueda J, Messerschmidt DM, Lorthongpanich C, Zhou Y, Feng B, Guo G, Lin PJ, Hossain MZ, Zhang W, Moh A, Wu Q, Robson P, Ng HH, Poellinger L, ... ... Fu XY, et al. A genetic and developmental pathway from STAT3 to the OCT4-NANOG circuit is essential for maintenance of ICM lineages in vivo. Genes & Development. 27: 1378-90. PMID 23788624 DOI: 10.1101/Gad.221176.113  0.474
2012 Mantel C, Messina-Graham S, Moh A, Cooper S, Hangoc G, Fu XY, Broxmeyer HE. Mouse hematopoietic cell-targeted STAT3 deletion: stem/progenitor cell defects, mitochondrial dysfunction, ROS overproduction, and a rapid aging-like phenotype. Blood. 120: 2589-99. PMID 22665934 DOI: 10.1182/Blood-2012-01-404004  0.367
2011 Cai Z, Simons DL, Fu XY, Feng GS, Wu SM, Zhang X. Loss of Shp2-mediated mitogen-activated protein kinase signaling in Muller glial cells results in retinal degeneration. Molecular and Cellular Biology. 31: 2973-83. PMID 21576358 DOI: 10.1128/MCB.05054-11  0.36
2011 Ding J, Batista AL, Rodriguez-Rodriguez S, Wang L, Zhang W, Moh A, Fu X, Shou W, Carlesso N, Cardoso AA. STAT3 Is Required for Notch-Induced Leukemogenesis, and Functions As a Critical Survival Effector in T-Cell Leukemia Blood. 118: 920-920. DOI: 10.1182/Blood.V118.21.920.920  0.485
2010 Zhang SS, Li H, Huang P, Lou LX, Fu XY, Barnstable CJ. MAPK signaling during Müller glial cell development in retina explant cultures. Journal of Ocular Biology, Diseases, and Informatics. 3: 129-33. PMID 22888395 DOI: 10.1007/s12177-011-9064-8  0.706
2010 Li C, Li YP, Fu XY, Deng CX. Anterior visceral endoderm SMAD4 signaling specifies anterior embryonic patterning and head induction in mice. International Journal of Biological Sciences. 6: 569-83. PMID 20941375 DOI: 10.7150/Ijbs.6.569  0.395
2010 Mantel C, Messina-Graham S, Moh A, Fu X, Broxmeyer HE. STAT3 Deletion In Hematopoietic Tissue Causes Mitochondrial Dysfunction with Increased ROS Leading to LT-Repopulating Stem Cell Depletion, Erythroid Dysplasia, Peripheral Neutrophilia, and a Rapid Aging-Like Phenotype. Blood. 116: 2621-2621. DOI: 10.1182/Blood.V116.21.2621.2621  0.418
2009 Lafdil F, Wang H, Park O, Zhang W, Moritoki Y, Yin S, Fu XY, Gershwin ME, Lian ZX, Gao B. Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production. Gastroenterology. 137: 2125-35.e1-2. PMID 19686746 DOI: 10.1053/j.gastro.2009.08.004  0.301
2009 Zhang W, Chan RJ, Chen H, Yang Z, He Y, Zhang X, Luo Y, Yin F, Moh A, Miller LC, Payne RM, Zhang ZY, Fu XY, Shou W. Negative regulation of Stat3 by activating PTPN11 mutants contributes to the pathogenesis of Noonan syndrome and juvenile myelomonocytic leukemia. The Journal of Biological Chemistry. 284: 22353-63. PMID 19509418 DOI: 10.1074/Jbc.M109.020495  0.318
2009 Fukuda S, Singh P, Moh A, Abe M, Conway EM, Boswell HS, Yamaguchi S, Fu XY, Pelus LM. Survivin mediates aberrant hematopoietic progenitor cell proliferation and acute leukemia in mice induced by internal tandem duplication of Flt3. Blood. 114: 394-403. PMID 19411632 DOI: 10.1182/Blood-2008-11-188714  0.431
2009 Wegrzyn J, Potla R, Chwae YJ, Sepuri NB, Zhang Q, Koeck T, Derecka M, Szczepanek K, Szelag M, Gornicka A, Moh A, Moghaddas S, Chen Q, Bobbili S, Cichy J, ... ... Fu XY, et al. Function of mitochondrial Stat3 in cellular respiration. Science (New York, N.Y.). 323: 793-7. PMID 19131594 DOI: 10.1126/Science.1164551  0.345
2009 Mantel C, Messina-Graham S, Moh A, Fu X, Broxmeyer HE. The Earliest Stages of Loss of Stem Cell Self-Renewal in-Vivo Is Linked to Upregulated Biosynthesis of “Quiet” Mitochondria and Is Influenced by CXCR4 Activation and STAT3 Gene Deletion. Blood. 114: 2546-2546. DOI: 10.1182/Blood.V114.22.2546.2546  0.378
2008 Zhang C, Li H, Liu MG, Kawasaki A, Fu XY, Barnstable CJ, Shao-Min Zhang S. STAT3 activation protects retinal ganglion cell layer neurons in response to stress. Experimental Eye Research. 86: 991-7. PMID 18471811 DOI: 10.1016/J.Exer.2008.03.020  0.334
2008 Fu X, Zhang W, Cooper S, Hangoc G, Moh A, Broxmeyer HE. Potential roles of STAT3 in control of differentiation of hematopoietic and neuronal progenitors Cell Research. 18: S14-S14. DOI: 10.1038/Cr.2008.104  0.307
2008 Wegrzyn J, Potla R, Chwae Y, Zhang Q, Derecka M, Szczepanek K, Szelag M, Gornicka A, Moh A, Moghaddas S, Chen Q, Bobbili S, Fu X, Lesnefsky EJ. 372 A novel function of STAT3 in cellular respiration Cytokine. 43: 331. DOI: 10.1016/J.Cyto.2008.07.457  0.334
2007 Moh A, Iwamoto Y, Chai GX, Zhang SS, Kano A, Yang DD, Zhang W, Wang J, Jacoby JJ, Gao B, Flavell RA, Fu XY. Role of STAT3 in liver regeneration: survival, DNA synthesis, inflammatory reaction and liver mass recovery. Laboratory Investigation; a Journal of Technical Methods and Pathology. 87: 1018-28. PMID 17660847 DOI: 10.1038/Labinvest.3700630  0.486
2006 Zhang SS, Xu X, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY. A biphasic pattern of gene expression during mouse retina development. Bmc Developmental Biology. 6: 48. PMID 17044933 DOI: 10.1186/1471-213X-6-48  0.654
2006 Zhang X, Shan P, Jiang G, Zhang SS, Otterbein LE, Fu XY, Lee PJ. Endothelial STAT3 is essential for the protective effects of HO-1 in oxidant-induced lung injury. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 20: 2156-8. PMID 16971418 DOI: 10.1096/Fj.06-5668Fje  0.356
2006 Rong Y, Cheng L, Ning H, Zou J, Zhang Y, Xu F, Liu L, Chang Z, Fu XY. Wilms' tumor 1 and signal transducers and activators of transcription 3 synergistically promote cell proliferation: a possible mechanism in sporadic Wilms' tumor. Cancer Research. 66: 8049-57. PMID 16912181 DOI: 10.1158/0008-5472.CAN-06-1172  0.426
2006 Zhang X, He X, Fu XY, Chang Z. Varp is a Rab21 guanine nucleotide exchange factor and regulates endosome dynamics. Journal of Cell Science. 119: 1053-62. PMID 16525121 DOI: 10.1242/jcs.02810  0.356
2006 Li TS, Li XN, Chang ZJ, Fu XY, Liu L. Identification and functional characterization of a novel interleukin 17 receptor: a possible mitogenic activation through ras/mitogen-activated protein kinase signaling pathway. Cellular Signalling. 18: 1287-98. PMID 16310341 DOI: 10.1016/J.Cellsig.2005.10.010  0.541
2005 Zhang SS, Liu MG, Kano A, Zhang C, Fu XY, Barnstable CJ. STAT3 activation in response to growth factors or cytokines participates in retina precursor proliferation. Experimental Eye Research. 81: 103-15. PMID 15978261 DOI: 10.1016/j.exer.2005.01.016  0.704
2005 Xin H, Xu X, Li L, Ning H, Rong Y, Shang Y, Wang Y, Fu XY, Chang Z. CHIP controls the sensitivity of transforming growth factor-beta signaling by modulating the basal level of Smad3 through ubiquitin-mediated degradation. The Journal of Biological Chemistry. 280: 20842-50. PMID 15781469 DOI: 10.1074/jbc.M412275200  0.334
2005 Zhang SS, Xu X, Li J, Liu MG, Zhao H, Soares MB, Barnstable CJ, Fu XY. Comprehensive in silico functional specification of mouse retina transcripts. Bmc Genomics. 6: 40. PMID 15777472 DOI: 10.1186/1471-2164-6-40  0.664
2005 Zhang Z, Welte T, Troiano N, Maher SE, Fu XY, Bothwell AL. Osteoporosis with increased osteoclastogenesis in hematopoietic cell-specific STAT3-deficient mice. Biochemical and Biophysical Research Communications. 328: 800-7. PMID 15694417 DOI: 10.1016/j.bbrc.2005.01.019  0.416
2005 Broxmeyer HE, Cooper S, Hangoc G, Zhang W, Moh A, Welte T, Fu X. STAT3 Deletion after Birth Results in Marked Decreases in Absolute Numbers and Cell Cycling Status of Marrow and Spleen Myeloid Progenitor Cells, and STAT3 Is a Critical Molecule in Mediating Synergistically Stimulated Progenitor Cell Proliferation. Blood. 106: 1346-1346. DOI: 10.1182/Blood.V106.11.1346.1346  0.41
2004 Zhang SS, Wei J, Qin H, Zhang L, Xie B, Hui P, Deisseroth A, Barnstable CJ, Fu XY. STAT3-mediated signaling in the determination of rod photoreceptor cell fate in mouse retina. Investigative Ophthalmology & Visual Science. 45: 2407-12. PMID 15223824 DOI: 10.1167/iovs.04-0003  0.744
2004 Liu L, Yu XZ, Li TS, Song LX, Chen PL, Suo TL, Li YH, Wang SD, Chen Y, Ren YM, Zhang SP, Chang ZJ, Fu XY. A novel protein tyrosine kinase NOK that shares homology with platelet- derived growth factor/fibroblast growth factor receptors induces tumorigenesis and metastasis in nude mice. Cancer Research. 64: 3491-9. PMID 15150103 DOI: 10.1158/0008-5472.CAN-03-2106  0.542
2004 Gao Q, Hua J, Kimura R, Headd JJ, Fu XY, Chin YE. Identification of the linker-SH2 domain of STAT as the origin of the SH2 domain using two-dimensional structural alignment. Molecular & Cellular Proteomics : McP. 3: 704-14. PMID 15073273 DOI: 10.1074/Mcp.M300131-Mcp200  0.331
2004 Gao Q, Wolfgang MJ, Neschen S, Morino K, Horvath TL, Shulman GI, Fu XY. Disruption of neural signal transducer and activator of transcription 3 causes obesity, diabetes, infertility, and thermal dysregulation. Proceedings of the National Academy of Sciences of the United States of America. 101: 4661-6. PMID 15070774 DOI: 10.1073/Pnas.0303992101  0.624
2004 Li L, Xin H, Xu X, Huang M, Zhang X, Chen Y, Zhang S, Fu XY, Chang Z. CHIP mediates degradation of Smad proteins and potentially regulates Smad-induced transcription. Molecular and Cellular Biology. 24: 856-64. PMID 14701756 DOI: 10.1128/Mcb.24.2.856-864.2004  0.386
2003 Xiao C, Shim JH, Klüppel M, Zhang SS, Dong C, Flavell RA, Fu XY, Wrana JL, Hogan BL, Ghosh S. Ecsit is required for Bmp signaling and mesoderm formation during mouse embryogenesis. Genes & Development. 17: 2933-49. PMID 14633973 DOI: 10.1101/Gad.1145603  0.732
2003 Kano A, Wolfgang MJ, Gao Q, Jacoby J, Chai GX, Hansen W, Iwamoto Y, Pober JS, Flavell RA, Fu XY. Endothelial cells require STAT3 for protection against endotoxin-induced inflammation. The Journal of Experimental Medicine. 198: 1517-25. PMID 14623907 DOI: 10.1084/Jem.20030077  0.713
2003 Jacoby JJ, Kalinowski A, Liu MG, Zhang SS, Gao Q, Chai GX, Ji L, Iwamoto Y, Li E, Schneider M, Russell KS, Fu XY. Cardiomyocyte-restricted knockout of STAT3 results in higher sensitivity to inflammation, cardiac fibrosis, and heart failure with advanced age. Proceedings of the National Academy of Sciences of the United States of America. 100: 12929-34. PMID 14566054 DOI: 10.1073/Pnas.2134694100  0.716
2003 Zhang SS, Wei JY, Li C, Barnstable CJ, Fu XY. Expression and activation of STAT proteins during mouse retina development. Experimental Eye Research. 76: 421-31. PMID 12634107 DOI: 10.1016/S0014-4835(03)00002-2  0.717
2003 Welte T, Zhang SS, Wang T, Zhang Z, Hesslein DG, Yin Z, Kano A, Iwamoto Y, Li E, Craft JE, Bothwell AL, Fikrig E, Koni PA, Flavell RA, Fu XY. STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity. Proceedings of the National Academy of Sciences of the United States of America. 100: 1879-84. PMID 12571365 DOI: 10.1073/Pnas.0237137100  0.698
2002 Zhang SS, Fu XY, Barnstable CJ. Tissue culture studies of retinal development. Methods (San Diego, Calif.). 28: 439-47. PMID 12507462 DOI: 10.1016/S1046-2023(02)00263-3  0.656
2002 Zhang SS, Fu XY, Barnstable CJ. Molecular aspects of vertebrate retinal development. Molecular Neurobiology. 26: 137-52. PMID 12428752 DOI: 10.1385/MN:26:2-3:137  0.681
2001 al-Ramadi BK, Welte T, Fernandez-Cabezudo MJ, Galadari S, Dittel B, Fu XY, Bothwell AL. The Src-protein tyrosine kinase Lck is required for IL-1-mediated costimulatory signaling in Th2 cells. Journal of Immunology (Baltimore, Md. : 1950). 167: 6827-33. PMID 11739499 DOI: 10.4049/Jimmunol.167.12.6827  0.384
2001 Zhang SS, Welte T, Fu XY. Dysfunction of Stat4 leads to accelerated incidence of chemical-induced thymic lymphomas in mice. Experimental and Molecular Pathology. 70: 231-8. PMID 11418001 DOI: 10.1006/Exmp.2001.2360  0.683
2000 Ehrhard KN, Jacoby JJ, Fu XY, Jahn R, Dohlman HG. Use of G-protein fusions to monitor integral membrane protein-protein interactions in yeast. Nature Biotechnology. 18: 1075-9. PMID 11017046 DOI: 10.1038/80274  0.43
2000 Chang TL, Peng X, Fu XY. Interleukin-4 mediates cell growth inhibition through activation of Stat1. The Journal of Biological Chemistry. 275: 10212-7. PMID 10744706 DOI: 10.1074/Jbc.275.14.10212  0.399
2000 Asao H, Fu XY. Interferon-gamma has dual potentials in inhibiting or promoting cell proliferation. The Journal of Biological Chemistry. 275: 867-74. PMID 10625620 DOI: 10.1074/jbc.275.2.867  0.618
1999 Jones FE, Welte T, Fu XY, Stern DF. ErbB4 signaling in the mammary gland is required for lobuloalveolar development and Stat5 activation during lactation. The Journal of Cell Biology. 147: 77-88. PMID 10508857 DOI: 10.1083/Jcb.147.1.77  0.448
1999 Li C, Chen L, Iwata T, Kitagawa M, Fu XY, Deng CX. A Lys644Glu substitution in fibroblast growth factor receptor 3 (FGFR3) causes dwarfism in mice by activation of STATs and ink4 cell cycle inhibitors. Human Molecular Genetics. 8: 35-44. PMID 9887329 DOI: 10.1093/Hmg/8.1.35  0.551
1999 Welte T, Leitenberg D, Dittel BN, al-Ramadi BK, Xie B, Chin YE, Janeway CA, Bothwell AL, Bottomly K, Fu XY. STAT5 interaction with the T cell receptor complex and stimulation of T cell proliferation. Science (New York, N.Y.). 283: 222-5. PMID 9880255 DOI: 10.1126/Science.283.5399.222  0.568
1998 Iwamoto Y, Chin YE, Peng X, Fu XY. Identification of a membrane-associated inhibitor(s) of epidermal growth factor-induced signal transducer and activator of transcription activation. The Journal of Biological Chemistry. 273: 18198-204. PMID 9660781 DOI: 10.1074/jbc.273.29.18198  0.451
1997 Su WC, Kitagawa M, Xue N, Xie B, Garofalo S, Cho J, Deng C, Horton WA, Fu XY. Activation of Stat1 by mutant fibroblast growth-factor receptor in thanatophoric dysplasia type II dwarfism. Nature. 386: 288-92. PMID 9069288 DOI: 10.1038/386288A0  0.638
1993 Fu XY, Zhang JJ. Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter. Cell. 74: 1135-45. PMID 8402883 DOI: 10.1016/0092-8674(93)90734-8  0.372
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