Minhang Xin - Publications

Affiliations: 
2017 Georgia State University, Atlanta, GA, United States 

32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Feng Y, Duan W, Fan S, Zhang H, Zhang SQ, Xin M. Synthesis and biological evaluation of 4-(piperid-3-yl)amino substituted 6-pyridylquinazolines as potent PI3Kδ inhibitors. Bioorganic & Medicinal Chemistry. 115035. PMID 31434616 DOI: 10.1016/j.bmc.2019.07.051  0.84
2019 Hei YY, Zhang SQ, Feng Y, Wang J, Duan W, Zhang H, Mao S, Sun H, Xin M. Alkylsulfonamide-containing quinazoline derivatives as potent and orally bioavailable PI3Ks inhibitors. Bioorganic & Medicinal Chemistry. PMID 31176568 DOI: 10.1016/j.bmc.2019.05.043  0.84
2019 Liang C, Tian D, Liu Y, Li H, Zhu J, Li M, Xin M, Xia J. Review of the molecular mechanisms of Ganoderma lucidum triterpenoids: Ganoderic acids A, C2, D, F, DM, X and Y. European Journal of Medicinal Chemistry. 174: 130-141. PMID 31035236 DOI: 10.1016/j.ejmech.2019.04.039  0.72
2019 Wang Y, Huang W, Xin M, Chen P, Gui L, Zhao X, Zhu X, Luo H, Cong X, Wang J, Liu F. Discovery of potent anti-inflammatory 4-(4,5,6,7-tetrahydrofuro[3,2-c]pyridin-2-yl) pyrimidin-2-amines for use as Janus kinase inhibitors. Bioorganic & Medicinal Chemistry. PMID 30926315 DOI: 10.1016/j.bmc.2019.03.048  0.68
2019 Mao S, Luo K, Wang L, Zhao HY, Shergalis A, Xin M, Neamati N, Jin Y, Zhang SQ. Metal-Free C-2-H Alkylation of Quinazolin-4-ones with Alkanes via Cross-Dehydrogenative Coupling. Organic Letters. PMID 30907598 DOI: 10.1021/acs.orglett.9b00638  0.84
2018 Mao S, Chen Z, Wang L, Khadka DB, Xin M, Li P, Zhang SQ. Synthesis of Aryl Trimethylstannane via BF3·OEt2-mediated Cross-Coupling of Hexaalkyl Distannane Reagent with Aryl Triazene at Room Temperature. The Journal of Organic Chemistry. PMID 30540911 DOI: 10.1021/acs.joc.8b02766  0.84
2018 Wang HY, Shen Y, Zhang H, Hei YY, Zhao HY, Xin M, Lu SM, Zhang SQ. Discovery of 2-(aminopyrimidin-5-yl)-4-(morpholin-4-yl)-6- substituted triazine as PI3K and BRAF dual inhibitor. Future Medicinal Chemistry. PMID 30325235 DOI: 10.4155/fmc-2018-0145  0.84
2018 Zhang H, Wang J, Zhao HY, Yang XY, Lei H, Xin M, Cao YX, Zhang SQ. Synthesis and biological evaluation of irreversible EGFR tyrosine kinase inhibitors containing pyrido[3,4-d]pyrimidine scaffold. Bioorganic & Medicinal Chemistry. PMID 29853340 DOI: 10.1016/j.bmc.2018.05.039  0.84
2018 Liang C, Tian D, Ren X, Ding S, Jia M, Xin M, Thareja S. The development of Bruton's tyrosine kinase (BTK) inhibitors from 2012 to 2017: A mini-review. European Journal of Medicinal Chemistry. 151: 315-326. PMID 29631132 DOI: 10.1016/j.ejmech.2018.03.062  0.88
2018 Hei YY, Shen Y, Wang J, Zhang H, Zhao HY, Xin M, Cao YX, Li Y, Zhang SQ. Synthesis and evaluation of 2,9-disubstituted 8-phenylthio/phenylsulfinyl-9H-purine as new EGFR inhibitors. Bioorganic & Medicinal Chemistry. PMID 29576272 DOI: 10.1016/j.bmc.2018.03.025  0.84
2018 Xin M, Duan W, Feng Y, Hei YY, Zhang H, Shen Y, Zhao HY, Mao S, Zhang SQ. Introduction of pyrrolidineoxy or piperidineamino group at the 4-position of quinazoline leading to novel quinazoline-based phosphoinositide 3-kinase delta (PI3Kδ) inhibitors. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 651-656. PMID 29536777 DOI: 10.1080/14756366.2018.1444608  0.84
2018 Xin M, Duan W, Feng Y, Hei YY, Zhang H, Shen Y, Zhao HY, Mao S, Zhang SQ. Novel 6-aryl substituted 4-pyrrolidineaminoquinazoline derivatives as potent phosphoinositide 3-kinase delta (PI3Kδ) inhibitors. Bioorganic & Medicinal Chemistry. PMID 29534936 DOI: 10.1016/j.bmc.2018.03.002  0.84
2018 Zhang H, Wang J, Shen Y, Wang HY, Duan WM, Zhao HY, Hei YY, Xin M, Cao YX, Zhang SQ. Discovery of 2,4,6-trisubstitued pyrido[3,4-d]pyrimidine derivatives as new EGFR-TKIs. European Journal of Medicinal Chemistry. 148: 221-237. PMID 29466773 DOI: 10.1016/j.ejmech.2018.02.051  0.84
2018 Xin M, Ji X, De La Cruz LK, Thareja S, Wang B. Strategies to target the Hedgehog signaling pathway for cancer therapy. Medicinal Research Reviews. PMID 29315702 DOI: 10.1002/med.21482  0.88
2017 Zhao HY, Wang HY, Mao S, Xin M, Zhang H, Zhang SQ. Discovery of 2-(pyridin-2-yl)aniline as a directing group for the sp(2) C-H bond amination mediated by cupric acetate. Organic & Biomolecular Chemistry. PMID 28752166 DOI: 10.1039/c7ob01353a  0.84
2017 Xin M, Zhang L, Wen J, Shen H, Zhao X, Jin Q, Tang F. Introduction of fluorine to phenyl group of 4-(2-pyrimidinylamino)benzamides leading to a series of potent hedgehog signaling pathway inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28642101 DOI: 10.1016/j.bmcl.2017.06.030  0.6
2017 Xin M, Hei YY, Zhang H, Shen Y, Zhang SQ. Design and synthesis of novel 6-aryl substituted 4-anilinequinazoline derivatives as potential PI3Kδ inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 28325601 DOI: 10.1016/j.bmcl.2017.03.020  0.84
2016 Wang Y, Huang W, Xin M, Chen P, Gui L, Zhao X, Tang F, Wang J, Liu F. Identification of 4-(2-furanyl)pyrimidin-2-amines as Janus kinase 2 inhibitors. Bioorganic & Medicinal Chemistry. PMID 27771180 DOI: 10.1016/j.bmc.2016.10.011  0.68
2016 Hei YY, Xin M, Zhang H, Xie XX, Mao S, Zhang SQ. Synthesis and antitumor activity evaluation of 4,6-disubstituted quinazoline derivatives as novel PI3K inhibitors. Bioorganic & Medicinal Chemistry Letters. PMID 27544401 DOI: 10.1016/j.bmcl.2016.08.015  0.84
2016 Xin M, Zhang L, Wen J, Shen H, Liu Z, Zhao X, Jin Q, Wang M, Cheng L, Huang W, Tang F. Synthesis and pharmacological evaluation of trifluoromethyl containing 4-(2-pyrimidinylamino)benzamides as Hedgehog signaling pathway inhibitors. Bioorganic & Medicinal Chemistry. PMID 26827136 DOI: 10.1016/j.bmc.2016.01.034  0.56
2016 Xin M, Zhang L, Jin Q, Tang F, Wen J, Gu L, Cheng L, Zhao Y. Discovery of novel 4-(2-pyrimidinylamino)benzamide derivatives as highly potent and orally available hedgehog signaling pathway inhibitors. European Journal of Medicinal Chemistry. 110: 115-125. PMID 26820554 DOI: 10.1016/j.ejmech.2016.01.018  0.56
2015 Xin M, Zhao X, Huang W, Jin Q, Wu G, Wang Y, Tang F, Xiang H. Synthesis and biological evaluation of novel 7-substituted 3-(4-phenoxyphenyl)thieno[3,2-c]pyridin-4-amines as potent Bruton's tyrosine kinase (BTK) inhibitors. Bioorganic & Medicinal Chemistry. 23: 6250-7. PMID 26344595 DOI: 10.1016/j.bmc.2015.08.039  0.6
2015 Zhao X, Xin M, Wang Y, Huang W, Jin Q, Tang F, Wu G, Zhao Y, Xiang H. Discovery of thieno[3,2-c]pyridin-4-amines as novel Bruton's tyrosine kinase (BTK) inhibitors. Bioorganic & Medicinal Chemistry. PMID 26277759 DOI: 10.1016/j.bmc.2015.05.043  0.56
2015 Zhao X, Huang W, Wang Y, Xin M, Jin Q, Cai J, Tang F, Zhao Y, Xiang H. Pyrrolo[2,3-b]pyridine derivatives as potent Bruton's tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry. 23: 4344-4353. PMID 26169764 DOI: 10.1016/j.bmc.2015.06.023  0.56
2015 Xin M. Hedgehog inhibitors: a patent review (2013 - present). Expert Opinion On Therapeutic Patents. 25: 549-65. PMID 25726713 DOI: 10.1517/13543776.2015.1019864  0.56
2015 Zhao X, Huang W, Wang Y, Xin M, Jin Q, Cai J, Tang F, Zhao Y, Xiang H. Discovery of novel Bruton's tyrosine kinase (BTK) inhibitors bearing a pyrrolo[2,3-d]pyrimidine scaffold. Bioorganic & Medicinal Chemistry. 23: 891-901. PMID 25596757 DOI: 10.1016/j.bmc.2014.10.043  0.56
2015 Zhao X, Xin M, Huang W, Ren Y, Jin Q, Tang F, Jiang H, Wang Y, Yang J, Mo S, Xiang H. Design, synthesis and evaluation of novel 5-phenylpyridin-2(1H)-one derivatives as potent reversible Bruton's tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry. 23: 348-64. PMID 25515957 DOI: 10.1016/j.bmc.2014.11.006  0.56
2014 Zhang L, Xin M, Shen H, Wen J, Tang F, Tu C, Zhao X, Wei P. Five-membered heteroaromatic ring fused-pyrimidine derivatives: design, synthesis, and hedgehog signaling pathway inhibition study. Bioorganic & Medicinal Chemistry Letters. 24: 3486-92. PMID 24923765 DOI: 10.1016/j.bmcl.2014.05.066  0.56
2014 Xin M, Zhang L, Tang F, Tu C, Wen J, Zhao X, Liu Z, Cheng L, Shen H. Design, synthesis, and evaluation of pyrrolo[2,1-f][1,2,4]triazine derivatives as novel hedgehog signaling pathway inhibitors. Bioorganic & Medicinal Chemistry. 22: 1429-40. PMID 24486203 DOI: 10.1016/j.bmc.2013.12.055  0.56
2014 Xin M, Wen J, Tang F, Tu C, Huang W, Shen H, Zhao X, Cheng L, Wang M, Zhang L. Synthesis and evaluation of 4-(2-pyrimidinylamino) benzamides inhibitors of hedgehog signaling pathway. Bioorganic & Medicinal Chemistry Letters. 24: 983-8. PMID 24405704 DOI: 10.1016/j.bmcl.2013.12.050  0.56
2013 Xin M, Wen J, Tang F, Tu C, Shen H, Zhao X. The discovery of novel N-(2-pyrimidinylamino) benzamide derivatives as potent hedgehog signaling pathway inhibitors. Bioorganic & Medicinal Chemistry Letters. 23: 6777-83. PMID 24176396 DOI: 10.1016/j.bmcl.2013.10.022  0.6
2010 Xin M, You Q, Xiang H. An efficient, practical synthesis of 2-methoxyestradiol. Steroids. 75: 53-6. PMID 19835898 DOI: 10.1016/j.steroids.2009.09.013  0.56
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