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Clifford D. Mol - Publications

Affiliations: 
Scripps Research Institute, La Jolla, La Jolla, CA, United States 
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2013 Tsutakawa SE, Shin DS, Mol CD, Izumi T, Arvai AS, Mantha AK, Szczesny B, Ivanov IN, Hosfield DJ, Maiti B, Pique ME, Frankel KA, Hitomi K, Cunningham RP, Mitra S, et al. Conserved structural chemistry for incision activity in structurally non-homologous apurinic/apyrimidinic endonuclease APE1 and endonuclease IV DNA repair enzymes. The Journal of Biological Chemistry. 288: 8445-55. PMID 23355472 DOI: 10.1074/Jbc.M112.422774  0.802
2009 Mol CD, Okada K, Hosfield DJ. Protein Kinase Structural Biology: Methods and Strategies for Targeted Drug Discovery Kinase Inhibitor Drugs. 485-500. DOI: 10.1002/9780470524961.ch19  0.631
2008 Hosfield DJ, Mol CD. Targeting inactive kinases: Structure as foundation for cancer drug discovery Cancer Drug Design and Discovery. 229-252. DOI: 10.1016/B978-012369448-5.50013-6  0.628
2004 Mol CD, Fabbro D, Hosfield DJ. Structural insights into the conformational selectivity of STI-571 and related kinase inhibitors. Current Opinion in Drug Discovery & Development. 7: 639-48. PMID 15503866  0.639
2004 Mol CD, Dougan DR, Schneider TR, Skene RJ, Kraus ML, Scheibe DN, Snell GP, Zou H, Sang BC, Wilson KP. Structural basis for the autoinhibition and STI-571 inhibition of c-Kit tyrosine kinase. The Journal of Biological Chemistry. 279: 31655-63. PMID 15123710 DOI: 10.1074/Jbc.M403319200  0.306
2003 Mol CD, Brooun A, Dougan DR, Hilgers MT, Tari LW, Wijnands RA, Knuth MW, McRee DE, Swanson RV. Crystal structures of active fully assembled substrate- and product-bound complexes of UDP-N-acetylmuramic acid:L-alanine ligase (MurC) from Haemophilus influenzae. Journal of Bacteriology. 185: 4152-62. PMID 12837790 DOI: 10.1128/Jb.185.14.4152-4162.2003  0.357
2003 Mol CD, Lim KB, Sridhar V, Zou H, Chien EY, Sang BC, Nowakowski J, Kassel DB, Cronin CN, McRee DE. Structure of a c-kit product complex reveals the basis for kinase transactivation. The Journal of Biological Chemistry. 278: 31461-4. PMID 12824176 DOI: 10.1074/Jbc.C300186200  0.309
2002 Mol CD, Arvai AS, Begley TJ, Cunningham RP, Tainer JA. Structure and activity of a thermostable thymine-DNA glycosylase: evidence for base twisting to remove mismatched normal DNA bases. Journal of Molecular Biology. 315: 373-84. PMID 11786018 DOI: 10.1006/Jmbi.2001.5264  0.802
2001 Hosfield DJ, Daniels DS, Mol CD, Putnam CD, Parikh SS, Tainer JA. DNA damage recognition and repair pathway coordination revealed by the structural biochemistry of DNA repair enzymes. Progress in Nucleic Acid Research and Molecular Biology. 68: 315-47. PMID 11554309 DOI: 10.1016/S0079-6603(01)68110-8  0.806
2000 Mol CD, Hosfield DJ, Tainer JA. Abasic site recognition by two apurinic/apyrimidinic endonuclease families in DNA base excision repair: the 3' ends justify the means. Mutation Research. 460: 211-29. PMID 10946230 DOI: 10.1016/S0921-8777(00)00028-8  0.852
2000 Daniels DS, Mol CD, Arvai AS, Kanugula S, Pegg AE, Tainer JA. Active and alkylated human AGT structures: a novel zinc site, inhibitor and extrahelical base binding. The Embo Journal. 19: 1719-30. PMID 10747039 DOI: 10.1093/Emboj/19.7.1719  0.822
2000 Mol CD, Izumi T, Mitra S, Tainer JA. DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination [corrected]. Nature. 403: 451-6. PMID 10667800 DOI: 10.1038/35000249  0.811
2000 Mol CD, Izumi T, Mitra S, Tainer JA. Erratum: DNA-bound structures and mutants reveal abasic DNA binding by APE1 and DNA repair coordination Nature. 404: 525-525. DOI: 10.1038/35006693  0.762
1999 Mol CD, Parikh SS, Putnam CD, Lo TP, Tainer JA. DNA repair mechanisms for the recognition and removal of damaged DNA bases. Annual Review of Biophysics and Biomolecular Structure. 28: 101-28. PMID 10410797 DOI: 10.1146/Annurev.Biophys.28.1.101  0.827
1999 Putnam CD, Shroyer MJ, Lundquist AJ, Mol CD, Arvai AS, Mosbaugh DW, Tainer JA. Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase. Journal of Molecular Biology. 287: 331-46. PMID 10080896 DOI: 10.1006/Jmbi.1999.2605  0.844
1999 Parikh SS, Mol CD, Hosfield DJ, Tainer JA. Envisioning the molecular choreography of DNA base excision repair. Current Opinion in Structural Biology. 9: 37-47. PMID 10047578 DOI: 10.1016/S0959-440X(99)80006-2  0.857
1998 Guan Y, Manuel RC, Arvai AS, Parikh SS, Mol CD, Miller JH, Lloyd S, Tainer JA. MutY catalytic core, mutant and bound adenine structures define specificity for DNA repair enzyme superfamily. Nature Structural Biology. 5: 1058-64. PMID 9846876 DOI: 10.1038/4168  0.835
1998 Hosfield DJ, Mol CD, Shen B, Tainer JA. Structure of the DNA repair and replication endonuclease and exonuclease FEN-1: coupling DNA and PCNA binding to FEN-1 activity. Cell. 95: 135-46. PMID 9778254 DOI: 10.1016/S0092-8674(00)81789-4  0.858
1998 Parikh SS, Mol CD, Slupphaug G, Bharati S, Krokan HE, Tainer JA. Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA. The Embo Journal. 17: 5214-26. PMID 9724657 DOI: 10.1093/Emboj/17.17.5214  0.853
1997 Parikh SS, Mol CD, Tainer JA. Base excision repair enzyme family portrait: integrating the structure and chemistry of an entire DNA repair pathway. Structure (London, England : 1993). 5: 1543-50. PMID 9438868 DOI: 10.1016/S0969-2126(97)00303-1  0.839
1997 Gorman MA, Morera S, Rothwell DG, de La Fortelle E, Mol CD, Tainer JA, Hickson ID, Freemont PS. The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra-helical deoxyribose at DNA abasic sites. The Embo Journal. 16: 6548-58. PMID 9351835 DOI: 10.1093/Emboj/16.21.6548  0.727
1996 Slupphaug G, Mol CD, Kavli B, Arvai AS, Krokan HE, Tainer JA. A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA. Nature. 384: 87-92. PMID 8900285 DOI: 10.1038/384087A0  0.86
1996 Mol CD, Harris JM, McIntosh EM, Tainer JA. Human dUTP pyrophosphatase: uracil recognition by a beta hairpin and active sites formed by three separate subunits. Structure (London, England : 1993). 4: 1077-92. PMID 8805593 DOI: 10.1016/S0969-2126(96)00114-1  0.735
1996 Mol CD, Slupphaug G, Arvai AS, Tainer JA, Kavli B, Krokan HE. Structural basis for the removal and exclusion of uracil from DNA Acta Crystallographica Section a Foundations of Crystallography. 52: C157-C158. DOI: 10.1107/S010876739609294X  0.827
1996 Kavli B, Slupphaug G, Mol CD, Arvai AS, Peterson SB, Tainer JA, Krokan HE. Excision of cytosine and thymine from DNA by mutants of human uracil-DNA glycosylase. The Embo Journal. 15: 3442-3447. DOI: 10.1002/J.1460-2075.1996.Tb00710.X  0.831
1995 Mol CD, Kuo CF, Thayer MM, Cunningham RP, Tainer JA. Structure and function of the multifunctional DNA-repair enzyme exonuclease III. Nature. 374: 381-6. PMID 7885481 DOI: 10.1038/374381A0  0.73
1995 Mol CD, Arvai AS, Slupphaug G, Kavli B, Alseth I, Krokan HE, Tainer JA. Crystal structure and mutational analysis of human uracil-DNA glycosylase: structural basis for specificity and catalysis. Cell. 80: 869-78. PMID 7697717 DOI: 10.1016/0092-8674(95)90290-2  0.822
1995 Mol CD, Arvai AS, Sanderson RJ, Slupphaug G, Kavli B, Krokan HE, Mosbaugh DW, Tainer JA. Crystal structure of human uracil-DNA glycosylase in complex with a protein inhibitor: protein mimicry of DNA. Cell. 82: 701-8. PMID 7671300 DOI: 10.1016/0092-8674(95)90467-0  0.834
1995 Barzilay G, Mol CD, Robson CN, Walker LJ, Cunningham RP, Tainer JA, Hickson ID. Identification of critical active-site residues in the multifunctional human DNA repair enzyme HAP1. Nature Structural Biology. 2: 561-8. PMID 7664124 DOI: 10.1038/Nsb0795-561  0.703
1994 Kuo CF, Mol CD, Thayer MM, Cunningham RP, Tainer JA. Structure and function of the DNA repair enzyme exonuclease III from E. coli. Annals of the New York Academy of Sciences. 726: 223-34; discussion 2. PMID 8092679 DOI: 10.1111/J.1749-6632.1994.Tb52820.X  0.615
1988 Anderson WF, Boodhoo A, Mol CD. The importance of purity in the crystallization of DNA binding immunoglobulin Fab fragments Journal of Crystal Growth. 90: 153-159. DOI: 10.1016/0022-0248(88)90310-7  0.468
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