Paul Jackson - Publications

Affiliations: 
2012-2014 King's College London, London, UK 

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Pysz I, Jackson PJM, Barlow DJ, Rahman KM, Thurston DE. UPLC-based assay to assess the hydrophobicity of Antibody-Drug Conjugate (ADC) payloads. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1146: 122075. PMID 32361467 DOI: 10.1016/J.Jchromb.2020.122075  1
2020 Hoffmann RM, Crescioli S, Mele S, Sachouli E, Cheung A, Chui CK, Andriollo P, Jackson PJM, Lacy KE, Spicer JF, Thurston DE, Karagiannis SN. A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma. Cancers. 12. PMID 32331483 DOI: 10.3390/Cancers12041029  1
2018 Jackson PJM, Kay S, Pysz I, Thurston DE. Use of pyrrolobenzodiazepines and related covalent-binding DNA-interactive molecules as ADC payloads: Is mechanism related to systemic toxicity? Drug Discovery Today. Technologies. 30: 71-83. PMID 30553523 DOI: 10.1016/J.Ddtec.2018.10.004  1
2018 Islam MK, Jackson PJM, Thurston DE, Rahman KM. Methylene-linked bis-phenylbenzimidazoles - a new scaffold to target telomeric DNA/RNA hybrid duplex. Organic & Biomolecular Chemistry. PMID 29498732 DOI: 10.1039/C7Ob02709E  1
2017 Basher MA, Rahman KM, Jackson PJM, Thurston DE, Fox KR. Sequence-selective binding of C8-conjugated pyrrolobenzodiazepines (PBDs) to DNA. Biophysical Chemistry. PMID 28941814 DOI: 10.1016/J.Bpc.2017.08.006  1
2016 Jackson PJ, Rahman KM, Thurston DE. The use of molecular dynamics simulations to evaluate the DNA sequence-selectivity of G-A cross-linking PBD-duocarmycin dimers. Bioorganic & Medicinal Chemistry Letters. PMID 27889454 DOI: 10.1016/J.Bmcl.2016.10.022  0.76
2016 Mantaj J, Jackson PJ, Rahman KM, Thurston DE. From Anthramycin to Pyrrolobenzodiazepine (PBD)-Containing Antibody-Drug Conjugates (ADCs). Angewandte Chemie (International Ed. in English). PMID 27862776 DOI: 10.1002/Anie.201510610  0.76
2016 Islam MK, M Jackson PJ, Rahman KM, Thurston DE. Recent advances in targeting the telomeric G-quadruplex DNA sequence with small molecules as a strategy for anticancer therapies. Future Medicinal Chemistry. PMID 27442231 DOI: 10.4155/Fmc-2015-0017  0.6
2016 Mantaj J, Jackson PJ, Karu K, Rahman KM, Thurston DE. Covalent Bonding of Pyrrolobenzodiazepines (PBDs) to Terminal Guanine Residues within Duplex and Hairpin DNA Fragments. Plos One. 11: e0152303. PMID 27055050 DOI: 10.1371/Journal.Pone.0152303  0.76
2015 Thurston DE, Vassoler H, Jackson PJ, James CH, Rahman KM. Effect of hairpin loop structure on reactivity, sequence preference and adduct orientation of a DNA-interactive pyrrolo[2,1-c][1,4]benzodiazepine (PBD) antitumour agent. Organic & Biomolecular Chemistry. 13: 4031-40. PMID 25733051 DOI: 10.1039/C4Ob02405B  0.72
2015 Mantaj J, Rahman SM, Bokshi B, Hasan CM, Jackson PJ, Parsons RB, Rahman KM. Crispene E, a cis-clerodane diterpene inhibits STAT3 dimerization in breast cancer cells. Organic & Biomolecular Chemistry. 13: 3882-6. PMID 25721973 DOI: 10.1039/C5Ob00052A  0.72
2014 Rahman KM, Corcoran DB, Bui TT, Jackson PJ, Thurston DE. Pyrrolobenzodiazepines (PBDs) do not bind to DNA G-quadruplexes. Plos One. 9: e105021. PMID 25133504 DOI: 10.1371/Journal.Pone.0105021  0.76
2014 Jackson PJ, James CH, Jenkins TC, Rahman KM, Thurston DE. Computational studies support the role of the C7-sibirosamine sugar of the pyrrolobenzodiazepine (PBD) sibiromycin in transcription factor inhibition. Acs Chemical Biology. 9: 2432-40. PMID 25111266 DOI: 10.1021/Cb5002203  0.48
2013 Be NA, Thissen JB, Gardner SN, McLoughlin KS, Fofanov VY, Koshinsky H, Ellingson SR, Brettin TS, Jackson PJ, Jaing CJ. Detection of Bacillus anthracis DNA in complex soil and air samples using next-generation sequencing. Plos One. 8: e73455. PMID 24039948 DOI: 10.1371/Journal.Pone.0073455  0.48
2013 Brucoli F, Hawkins RM, James CH, Jackson PJ, Wells G, Jenkins TC, Ellis T, Kotecha M, Hochhauser D, Hartley JA, Howard PW, Thurston DE. An extended pyrrolobenzodiazepine-polyamide conjugate with selectivity for a DNA sequence containing the ICB2 transcription factor binding site. Journal of Medicinal Chemistry. 56: 6339-51. PMID 23889553 DOI: 10.1021/Jm4001852  0.72
2013 Heidelberger S, Zinzalla G, Antonow D, Essex S, Basu BP, Palmer J, Husby J, Jackson PJ, Rahman KM, Wilderspin AF, Zloh M, Thurston DE. Investigation of the protein alkylation sites of the STAT3:STAT3 inhibitor Stattic by mass spectrometry. Bioorganic & Medicinal Chemistry Letters. 23: 4719-22. PMID 23810499 DOI: 10.1016/J.Bmcl.2013.05.066  0.76
2013 Rahman KM, Jackson PJ, James CH, Basu BP, Hartley JA, de la Fuente M, Schatzlein A, Robson M, Pedley RB, Pepper C, Fox KR, Howard PW, Thurston DE. GC-targeted C8-linked pyrrolobenzodiazepine-biaryl conjugates with femtomolar in vitro cytotoxicity and in vivo antitumor activity in mouse models. Journal of Medicinal Chemistry. 56: 2911-35. PMID 23514599 DOI: 10.1021/Jm301882A  0.48
2012 Bourguet FA, Souza BE, Hinz AK, Coleman MA, Jackson PJ. Characterization of a novel lytic protein encoded by the Bacillus cereus E33L gene ampD as a Bacillus anthracis antimicrobial protein. Applied and Environmental Microbiology. 78: 3025-7. PMID 22344637 DOI: 10.1128/AEM.06906-11  0.48
2010 Foster JT, Allan GJ, Chan AP, Rabinowicz PD, Ravel J, Jackson PJ, Keim P. Single nucleotide polymorphisms for assessing genetic diversity in castor bean (Ricinus communis). Bmc Plant Biology. 10: 13. PMID 20082707 DOI: 10.1186/1471-2229-10-13  0.48
2010 Jackson PJ. The Use of MLVA and SNP Analysis to Study the Population Genetics of Pathogenic Bacteria Bacterial Population Genetics in Infectious Disease. 153-165. DOI: 10.1002/9780470600122.ch8  0.48
2008 Budowle B, Schutzer SE, Morse SA, Martinez KF, Chakraborty R, Marrone BL, Messenger SL, Murch RS, Jackson PJ, Williamson P, Harmon R, Velsko SP. Criteria for validation of methods in microbial forensics. Applied and Environmental Microbiology. 74: 5599-607. PMID 18658281 DOI: 10.1128/Aem.00966-08  0.48
2008 Okinaka RT, Henrie M, Hill KK, Lowery KS, Van Ert M, Pearson T, Schupp J, Kenefic L, Beaudry J, Hofstadler SA, Jackson PJ, Keim P. Single nucleotide polymorphism typing of Bacillus anthracis from Sverdlovsk tissue. Emerging Infectious Diseases. 14: 653-6. PMID 18394287 DOI: 10.3201/Eid1404.070984  0.48
2008 Macdonald TE, Helma CH, Ticknor LO, Jackson PJ, Okinaka RT, Smith LA, Smith TJ, Hill KK. Differentiation of Clostridium botulinum serotype A strains by multiple-locus variable-number tandem-repeat analysis. Applied and Environmental Microbiology. 74: 875-82. PMID 18083878 DOI: 10.1128/AEM.01539-07  0.48
2008 Druar C, Yu F, Barnes JL, Okinaka RT, Chantratita N, Beg S, Stratilo CW, Olive AJ, Soltes G, Russell ML, Limmathurotsakul D, Norton RE, Ni SX, Picking WD, Jackson PJ, et al. Evaluating Burkholderia pseudomallei Bip proteins as vaccines and Bip antibodies as detection agents. Fems Immunology and Medical Microbiology. 52: 78-87. PMID 17995960 DOI: 10.1111/J.1574-695X.2007.00345.X  0.48
2008 Turnbull PCB, Jackson PJ, Hill KK, Keim P, Kolstø AB, Beecher DJ. Longstanding Taxonomic Enigmas within the 'Bacillus cereus group' are on the Verge of being Resolved by Far-reaching Molecular Developments: forecasts on the possible outcome by an ad hoc team Applications and Systematics of Bacillus and Relatives. 23-36. DOI: 10.1002/9780470696743.ch3  0.48
2007 Challacombe JF, Altherr MR, Xie G, Bhotika SS, Brown N, Bruce D, Campbell CS, Campbell ML, Chen J, Chertkov O, Cleland C, Dimitrijevic M, Doggett NA, Fawcett JJ, Glavina T, ... ... Jackson PJ, et al. The complete genome sequence of Bacillus thuringiensis Al Hakam. Journal of Bacteriology. 189: 3680-1. PMID 17337577 DOI: 10.1128/Jb.00241-07  0.48
2007 Avashia SB, Riggins WS, Lindley C, Hoffmaster A, Drumgoole R, Nekomoto T, Jackson PJ, Hill KK, Williams K, Lehman L, Libal MC, Wilkins PP, Alexander J, Tvaryanas A, Betz T. Fatal pneumonia among metalworkers due to inhalation exposure to Bacillus cereus Containing Bacillus anthracis toxin genes. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 44: 414-6. PMID 17205450 DOI: 10.1086/510429  0.48
2007 Hill KK, Smith TJ, Helma CH, Ticknor LO, Foley BT, Svensson RT, Brown JL, Johnson EA, Smith LA, Okinaka RT, Jackson PJ, Marks JD. Genetic diversity among Botulinum Neurotoxin-producing clostridial strains. Journal of Bacteriology. 189: 818-32. PMID 17114256 DOI: 10.1128/JB.01180-06  0.48
2006 Hoffmaster AR, Hill KK, Gee JE, Marston CK, De BK, Popovic T, Sue D, Wilkins PP, Avashia SB, Drumgoole R, Helma CH, Ticknor LO, Okinaka RT, Jackson PJ. Characterization of Bacillus cereus isolates associated with fatal pneumonias: strains are closely related to Bacillus anthracis and harbor B. anthracis virulence genes. Journal of Clinical Microbiology. 44: 3352-60. PMID 16954272 DOI: 10.1128/JCM.00561-06  0.48
2006 Han CS, Xie G, Challacombe JF, Altherr MR, Bhotika SS, Brown N, Bruce D, Campbell CS, Campbell ML, Chen J, Chertkov O, Cleland C, Dimitrijevic M, Doggett NA, Fawcett JJ, ... ... Jackson PJ, et al. Pathogenomic sequence analysis of Bacillus cereus and Bacillus thuringiensis isolates closely related to Bacillus anthracis. Journal of Bacteriology. 188: 3382-90. PMID 16621833 DOI: 10.1128/Jb.188.9.3382-3390.2006  0.48
2005 Loberg RD, Neeley CK, Adam-Day LL, Fridman Y, St John LN, Nixdorf S, Jackson P, Kalikin LM, Pienta KJ. Differential expression analysis of MIM (MTSS1) splice variants and a functional role of MIM in prostate cancer cell biology International Journal of Oncology. 26: 1699-1705. PMID 15870888 DOI: 10.3892/Ijo.26.6.1699  0.48
2005 Jackson P, Marreiros A, Russell PJ. KAI1 tetraspanin and metastasis suppressor. The International Journal of Biochemistry & Cell Biology. 37: 530-4. PMID 15618009 DOI: 10.1016/j.biocel.2004.08.009  0.48
2004 Hill KK, Ticknor LO, Okinaka RT, Asay M, Blair H, Bliss KA, Laker M, Pardington PE, Richardson AP, Tonks M, Beecher DJ, Kemp JD, Kolstø AB, Wong AC, Keim P, ... Jackson PJ, et al. Fluorescent amplified fragment length polymorphism analysis of Bacillus anthracis, Bacillus cereus, and Bacillus thuringiensis isolates. Applied and Environmental Microbiology. 70: 1068-80. PMID 14766590 DOI: 10.1128/Aem.70.2.1068-1080.2004  0.48
2003 Downing SR, Russell PJ, Jackson P. Alterations of p53 are common in early stage prostate cancer. The Canadian Journal of Urology. 10: 1924-33. PMID 14503938  0.48
2003 Radnedge L, Agron PG, Hill KK, Jackson PJ, Ticknor LO, Keim P, Andersen GL. Genome differences that distinguish Bacillus anthracis from Bacillus cereus and Bacillus thuringiensis. Applied and Environmental Microbiology. 69: 2755-64. PMID 12732546 DOI: 10.1128/Aem.69.5.2755-2764.2003  0.48
2002 Huber BS, Allred DV, Carmen JC, Frame DD, Whiting DG, Cryan JR, Olson TR, Jackson PJ, Hill K, Laker MT, Robison RA. Random amplified polymorphic DNA and amplified fragment length polymorphism analyses of Pasteurella multocida isolates from fatal fowl cholera infections. Journal of Clinical Microbiology. 40: 2163-8. PMID 12037081 DOI: 10.1128/Jcm.40.6.2163-2168.2002  0.48
2002 Olivares JA, Stark PC, Jackson P. Liquid core waveguide for full imaging of electrophoretic separations. Analytical Chemistry. 74: 2008-13. PMID 12033300 DOI: 10.1021/ac0110808  0.48
2001 Ticknor LO, Kolstø AB, Hill KK, Keim P, Laker MT, Tonks M, Jackson PJ. Fluorescent Amplified Fragment Length Polymorphism Analysis of Norwegian Bacillus cereus and Bacillus thuringiensis Soil Isolates. Applied and Environmental Microbiology. 67: 4863-73. PMID 11571195 DOI: 10.1128/AEM.67.10.4863-4873.2001  0.48
2000 Keim P, Price LB, Klevytska AM, Smith KL, Schupp JM, Okinaka R, Jackson PJ, Hugh-Jones ME. Multiple-locus variable-number tandem repeat analysis reveals genetic relationships within Bacillus anthracis. Journal of Bacteriology. 182: 2928-36. PMID 10781564 DOI: 10.1128/Jb.182.10.2928-2936.2000  0.48
2000 Adair DM, Worsham PL, Hill KK, Klevytska AM, Jackson PJ, Friedlander AM, Keim P. Diversity in a variable-number tandem repeat from Yersinia pestis. Journal of Clinical Microbiology. 38: 1516-9. PMID 10747136  0.48
1999 Jackson PJ, Hill KK, Laker MT, Ticknor LO, Keim P. Genetic comparison of Bacillus anthracis and its close relatives using amplified fragment length polymorphism and polymerase chain reaction analysis. Journal of Applied Microbiology. 87: 263-9. PMID 10475963 DOI: 10.1046/J.1365-2672.1999.00884.X  0.48
1999 Keim P, Klevytska AM, Price LB, Schupp JM, Zinser G, Smith KL, Hugh-Jones ME, Okinaka R, Hill KK, Jackson PJ. Molecular diversity in Bacillus anthracis. Journal of Applied Microbiology. 87: 215-7. PMID 10475952 DOI: 10.1046/J.1365-2672.1999.00873.X  0.48
1999 Cirino NM, Sblattero D, Allen D, Peterson SR, Marks JD, Jackson PJ, Bradbury A, Lehnert BE. Disruption of anthrax toxin binding with the use of human antibodies and competitive inhibitors. Infection and Immunity. 67: 2957-63. PMID 10338505 DOI: 10.1128/IAI.67.6.2957-2963.1999  0.48
1999 Price LB, Hugh-Jones M, Jackson PJ, Keim P. Genetic diversity in the protective antigen gene of Bacillus anthracis. Journal of Bacteriology. 181: 2358-62. PMID 10197996 DOI: 10.1128/Jb.181.8.2358-2362.1999  0.48
1999 Rayson GD, Drake LR, Xia H, Lin S, Jackson PJ. Biologically Generated Materials for Metal-Ion Binding: Answers to Some Fundamental Chemical Questions Acs Symposium Series. 716: 260-278.  0.48
1998 Kuske CR, Banton KL, Adorada DL, Stark PC, Hill KK, Jackson PJ. Small-Scale DNA Sample Preparation Method for Field PCR Detection of Microbial Cells and Spores in Soil. Applied and Environmental Microbiology. 64: 2463-72. PMID 9647816 DOI: 10.1128/AEM.64.7.2463-2472.1998  0.48
1998 Willardson BM, Wilkins JF, Rand TA, Schupp JM, Hill KK, Keim P, Jackson PJ. Development and testing of a bacterial biosensor for toluene-based environmental contaminants. Applied and Environmental Microbiology. 64: 1006-12. PMID 9501440 DOI: 10.1128/Aem.64.3.1006-1012.1998  0.48
1998 Jackson PJ, Hugh-Jones ME, Adair DM, Green G, Hill KK, Kuske CR, Grinberg LM, Abramova FA, Keim P. PCR analysis of tissue samples from the 1979 Sverdlovsk anthrax victims: the presence of multiple Bacillus anthracis strains in different victims. Proceedings of the National Academy of Sciences of the United States of America. 95: 1224-9. PMID 9448313 DOI: 10.1073/Pnas.95.3.1224  0.48
1997 Jackson PJ, Walthers EA, Kalif AS, Richmond KL, Adair DM, Hill KK, Kuske CR, Andersen GL, Wilson KH, Hugh-Jones M, Keim P. Characterization of the variable-number tandem repeats in vrrA from different Bacillus anthracis isolates. Applied and Environmental Microbiology. 63: 1400-5. PMID 9097438 DOI: 10.1128/Aem.63.4.1400-1405.1997  0.48
1997 Keim P, Kalif A, Schupp J, Hill K, Travis SE, Richmond K, Adair DM, Hugh-Jones M, Kuske CR, Jackson P. Molecular evolution and diversity in Bacillus anthracis as detected by amplified fragment length polymorphism markers. Journal of Bacteriology. 179: 818-24. PMID 9006038 DOI: 10.1128/Jb.179.3.818-824.1997  0.48
1997 Drake LR, Hensman CE, Lin S, Rayson GD, Jackson PJ. Characterization of metal ion binding sites on Datura innoxia by using lanthanide ion probe spectroscopy Applied Spectroscopy. 51: 1476-1483. DOI: 10.1366/0003702971939253  0.48
1996 Kuske CR, Hill KK, Guzman E, Jackson PJ. Subcellular Location of O-Acetylserine Sulfhydrylase Isoenzymes in Cell Cultures and Plant Tissues of Datura innoxia Mill. Plant Physiology. 112: 659-667. PMID 12226419  0.48
1996 Drake LR, Lin S, Rayson GD, Jackson PJ. Chemical modification and metal binding studies of Datura innoxia Environmental Science and Technology. 30: 110-114. DOI: 10.1021/Es950131D  0.48
1993 Ke HYD, Rayson GD, Jackson PJ. Luminescence study of Eu3+ binding to immobilized Datura innoxia biomaterial Environmental Science and Technology. 27: 2466-2471. DOI: 10.1021/Es00048A024  0.48
1993 Jackson PJ, Anderson WL, DeWitt JG, Ke HYD, Kuske CR, Moncrief RM, Rayson GD. Accumulation of toxic metal ions on cell walls of Datura innoxia suspension cell cultures In Vitro Cellular &Amp; Developmental Biology - Plant. 29: 220-226. DOI: 10.1007/Bf02632038  0.48
1992 Ke HYD, Birnbaum ER, Darnall DW, Rayson GD, Jackson PJ. Characterization of the carboxylate groups on Datura Innoxia using Eu(III) luminescence Environmental Science and Technology. 26: 782-788.  0.48
1989 Berger JM, Jackson PJ, Robinson NJ, Lujan LD, Delhaize E. Precursor-product relationships of Poly(γ-glutamylcysteinyl)glycine biosynthesis in Datura innoxia. Plant Cell Reports. 7: 632-5. PMID 24240448 DOI: 10.1007/BF00272047  0.48
1987 Jackson PJ, Unkefer CJ, Doolen JA, Watt K, Robinson NJ. Poly(gamma-glutamylcysteinyl)glycine: its role in cadmium resistance in plant cells. Proceedings of the National Academy of Sciences of the United States of America. 84: 6619-23. PMID 3477793 DOI: 10.1073/PNAS.84.19.6619  0.48
1987 Robinson NJ, Barton K, Naranjo CM, Sillerud LO, Trewhella J, Watt K, Jackson PJ. Characterization of metal binding peptides from cadmium resistant plant cells. Experientia. Supplementum. 52: 323-7. PMID 2889614 DOI: 10.1007/978-3-0348-6784-9_29  0.48
1986 Van Dilla MA, Deaven LL, Albright KL, Allen NA, Aubuchon MR, Bartholdi MF, Brown NC, Campbell EW, Carrano AV, Clark LM, Cram LS, Crawford BD, Fuscoe JC, Gray JW, Hildebrand CE, ... Jackson PJ, et al. Human chromosome–specific DNA libraries: Construction and availability Bio/Technology. 4: 537-552. DOI: 10.1038/Nbt0686-537  0.48
1984 Griffith JK, Cram LS, Crawford BD, Jackson PJ, Schilling J, Schimke RT, Walters RA, Wilder ME, Jett JH. Construction and analysis of DNA sequence libraries from flow-sorted chromosomes: practical and theoretical considerations. Nucleic Acids Research. 12: 4019-34. PMID 6587323 DOI: 10.1093/Nar/12.9.4019  0.48
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