Barry V. L. Potter, MA DPhil DSc FRSB FRSC MAE FMedSci - Publications

Affiliations: 
Max-Planck-Institute for Experimental Medicine, Göttingen, Germany 
 1984-1990 Biological Chemistry University of Leicester, Leicester, England, United Kingdom 
 1990- Medicine & Biological Chemistry University of Bath, Bath, England, United Kingdom 
 1998-2010 Sterix Ltd. 
 2015- Pharmacology University of Oxford, Oxford, United Kingdom 
Area:
medicinal chemistry, drug discovery, pharmacology
Website:
https://pharm.ox.ac.uk/research/potter-group-medicinal-biological-chemistry-drug-discovery

271 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Nel M, Joubert AM, Dohle W, Potter BV, Theron AE. Modes of cell death induced by tetrahydroisoquinoline-based analogs in MDA-MB-231 breast and A549 lung cancer cell lines. Drug Design, Development and Therapy. 12: 1881-1904. PMID 29983544 DOI: 10.2147/Dddt.S152718  0.634
2017 Fliegert R, Watt JM, Schöbel A, Rozewitz MD, Moreau C, Kirchberger T, Thomas MP, Sick W, Araujo AC, Harneit A, Potter BV, Guse AH. Ligand induced activation of human TRPM2 requires the terminal ribose of ADPR and involves Arg 1433 and Tyr 1349. The Biochemical Journal. PMID 28515263 DOI: 10.1042/Bcj20170091  0.791
2016 Thomas MP, Erneux C, Potter BV. SHIP2: Structure, Function and Inhibition. Chembiochem : a European Journal of Chemical Biology. PMID 27907247 DOI: 10.1002/Cbic.201600541  0.319
2016 Raimondi C, Calleja V, Ferro R, Fantin A, Riley AM, Potter BV, Brennan CH, Maffucci T, Larijani B, Falasca M. A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion. Scientific Reports. 6: 26142. PMID 27199173 DOI: 10.1038/Srep26142  0.615
2016 El-Gamal MI, Semreen MH, Foster PA, Potter BV. Design, synthesis, and biological evaluation of new arylamide derivatives possessing sulfonate or sulfamate moieties as steroid sulfatase enzyme inhibitors. Bioorganic & Medicinal Chemistry. PMID 27143133 DOI: 10.1016/J.Bmc.2016.04.040  0.363
2016 Watson PJ, Millard CJ, Riley AM, Robertson NS, Wright LC, Godage HY, Cowley SM, Jamieson AG, Potter BV, Schwabe JW. Insights into the activation mechanism of class I HDAC complexes by inositol phosphates. Nature Communications. 7: 11262. PMID 27109927 DOI: 10.1038/Ncomms11262  0.607
2016 Mills SJ, Silvander C, Cozier GE, Tresaugues L, Nordlund P, Potter BV. Crystal Structures of Type-II Inositol Polyphosphate 5-Phosphatase INPP5B with Synthetic Inositol Polyphosphate Surrogates Reveal New Mechanistic Insights for the Inositol 5-Phosphatase Family. Biochemistry. PMID 26854536 DOI: 10.1021/Acs.Biochem.5B00838  0.641
2015 Thomas MP, Mills SJ, Potter BV. The "Other" Inositols and Their Phosphates: Synthesis, Biology, and Medicine (with Recent Advances in myo-Inositol Chemistry). Angewandte Chemie (International Ed. in English). PMID 26694856 DOI: 10.1002/Anie.201502227  0.583
2015 Shen YC, Upadhyayula R, Cevallos S, Messick RJ, Hsia T, Leese MP, Jewett DM, Ferrer-Torres D, Roth TM, Dohle W, Potter BV, Barald KF. Targeted NF1 cancer therapeutics with multiple modes of action: small molecule hormone-like agents resembling the natural anticancer metabolite, 2-methoxyoestradiol. British Journal of Cancer. 113: 1158-67. PMID 26461061 DOI: 10.1038/Bjc.2015.345  0.63
2015 Thomas MP, Potter BV. Estrogen O-sulfamates and their analogues: Clinical steroid sulfatase inhibitors with broad potential. The Journal of Steroid Biochemistry and Molecular Biology. PMID 25843211 DOI: 10.1016/J.Jsbmb.2015.03.012  0.337
2014 Tsuzuki T, Takano S, Sakaguchi N, Kudoh T, Murayama T, Sakurai T, Hashii M, Higashida H, Weber K, Guse AH, Kameda T, Hirokawa T, Kumaki Y, Arisawa M, Potter BV, et al. Design, Synthesis, and Chemical and Biological Properties of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose. Messenger (Los Angeles, Calif. : Print). 3: 35-51. PMID 27200225 DOI: 10.1166/Msr.2014.1035  0.32
2014 Swarbrick JM, Graeff R, Zhang H, Thomas MP, Hao Q, Potter BV. Cyclic adenosine 5'-diphosphate ribose analogs without a "southern" ribose inhibit ADP-ribosyl cyclase-hydrolase CD38. Journal of Medicinal Chemistry. 57: 8517-29. PMID 25226087 DOI: 10.1021/Jm501037U  0.311
2014 Stengel C, Newman SP, Day JM, Chander SK, Jourdan FL, Leese MP, Ferrandis E, Regis-Lydi S, Potter BV, Reed MJ, Purohit A, Foster PA. In vivo and in vitro properties of STX2484: a novel non-steroidal anti-cancer compound active in taxane-resistant breast cancer. British Journal of Cancer. 111: 300-8. PMID 24960406 DOI: 10.1038/Bjc.2014.188  0.306
2014 Dohle W, Leese MP, Jourdan FL, Chapman CJ, Hamel E, Ferrandis E, Potter BV. Optimisation of tetrahydroisoquinoline-based chimeric microtubule disruptors. Chemmedchem. 9: 1783-93. PMID 24819406 DOI: 10.1002/Cmdc.201402025  0.673
2014 Wang H, Godage HY, Riley AM, Weaver JD, Shears SB, Potter BV. Synthetic inositol phosphate analogs reveal that PPIP5K2 has a surface-mounted substrate capture site that is a target for drug discovery. Chemistry & Biology. 21: 689-99. PMID 24768307 DOI: 10.1016/J.Chembiol.2014.03.009  0.597
2014 Leese MP, Jourdan FL, Major MR, Dohle W, Thomas MP, Hamel E, Ferrandis E, Mahon MF, Newman SP, Purohit A, Potter BV. Synthesis, anti-tubulin and antiproliferative SAR of steroidomimetic dihydroisoquinolinones. Chemmedchem. 9: 798-812. PMID 24596315 DOI: 10.1002/Cmdc.201400017  0.665
2014 Pulloor NK, Nair S, Kostic AD, Bist P, Weaver JD, Riley AM, Tyagi R, Uchil PD, York JD, Snyder SH, García-Sastre A, Potter BV, Lin R, Shears SB, Xavier RJ, et al. Human genome-wide RNAi screen identifies an essential role for inositol pyrophosphates in Type-I interferon response. Plos Pathogens. 10: e1003981. PMID 24586175 DOI: 10.1371/Journal.Ppat.1003981  0.588
2014 Swarbrick JM, Graeff R, Garnham C, Thomas MP, Galione A, Potter BV. 'Click cyclic ADP-ribose': a neutral second messenger mimic. Chemical Communications (Cambridge, England). 50: 2458-61. PMID 24452494 DOI: 10.1039/C3Cc49249D  0.344
2014 Dohle W, Leese MP, Jourdan FL, Major MR, Bai R, Hamel E, Ferrandis E, Kasprzyk PG, Fiore A, Newman SP, Purohit A, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of C3/C1-substituted tetrahydroisoquinolines. Chemmedchem. 9: 350-70. PMID 24436228 DOI: 10.1002/Cmdc.201300412  0.673
2014 Riley AM, Windhorst S, Lin HY, Potter BV. Cellular internalisation of an inositol phosphate visualised by using fluorescent InsP5. Chembiochem : a European Journal of Chemical Biology. 15: 57-67. PMID 24311195 DOI: 10.1002/Cbic.201300583  0.589
2014 Thomas MP, Potter BV. The enzymes of human diphosphoinositol polyphosphate metabolism. The Febs Journal. 281: 14-33. PMID 24152294 DOI: 10.1111/Febs.12575  0.303
2014 Leese MP, Jourdan FL, Major MR, Dohle W, Hamel E, Ferrandis E, Fiore A, Kasprzyk PG, Potter BV. Tetrahydroisoquinolinone-based steroidomimetic and chimeric microtubule disruptors. Chemmedchem. 9: 85-108, 1. PMID 24124095 DOI: 10.1002/Cmdc.201300261  0.676
2013 Moreau C, Kirchberger T, Swarbrick JM, Bartlett SJ, Fliegert R, Yorgan T, Bauche A, Harneit A, Guse AH, Potter BV. Structure-activity relationship of adenosine 5'-diphosphoribose at the transient receptor potential melastatin 2 (TRPM2) channel: rational design of antagonists. Journal of Medicinal Chemistry. 56: 10079-102. PMID 24304219 DOI: 10.1021/Jm401497A  0.392
2013 Moreau C, Liu Q, Graeff R, Wagner GK, Thomas MP, Swarbrick JM, Shuto S, Lee HC, Hao Q, Potter BV. CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5'-Diphosphate Ribose Template. Plos One. 8: e66247. PMID 23840430 DOI: 10.1371/Journal.Pone.0066247  0.581
2013 Tsuzuki T, Sakaguchi N, Kudoh T, Takano S, Uehara M, Murayama T, Sakurai T, Hashii M, Higashida H, Weber K, Guse AH, Kameda T, Hirokawa T, Kumaki Y, Potter BV, et al. Design and synthesis of cyclic ADP-4-thioribose as a stable equivalent of cyclic ADP-ribose, a calcium ion-mobilizing second messenger. Angewandte Chemie (International Ed. in English). 52: 6633-7. PMID 23670921 DOI: 10.1002/Anie.201302098  0.315
2013 Nebel M, Schwoerer AP, Warszta D, Siebrands CC, Limbrock AC, Swarbrick JM, Fliegert R, Weber K, Bruhn S, Hohenegger M, Geisler A, Herich L, Schlegel S, Carrier L, Eschenhagen T, ... Potter BV, et al. Nicotinic acid adenine dinucleotide phosphate (NAADP)-mediated calcium signaling and arrhythmias in the heart evoked by β-adrenergic stimulation. The Journal of Biological Chemistry. 288: 16017-30. PMID 23564460 DOI: 10.1074/Jbc.M112.441246  0.321
2013 Woo LW, Wood PM, Bubert C, Thomas MP, Purohit A, Potter BV. Synthesis and structure-activity relationship studies of derivatives of the dual aromatase-sulfatase inhibitor 4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl sulfamate. Chemmedchem. 8: 779-99. PMID 23495205 DOI: 10.1002/Cmdc.201300015  0.355
2013 Saleem H, Tovey SC, Riley AM, Potter BV, Taylor CW. Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by adenophostin A and its analogues. Plos One. 8: e58027. PMID 23469136 DOI: 10.1371/Journal.Pone.0058027  0.636
2013 Godage HY, Riley AM, Woodman TJ, Thomas MP, Mahon MF, Potter BV. Regioselective opening of myo-inositol orthoesters: mechanism and synthetic utility. The Journal of Organic Chemistry. 78: 2275-88. PMID 23438216 DOI: 10.1021/Jo3027774  0.595
2013 Saleem H, Tovey SC, Rahman T, Riley AM, Potter BV, Taylor CW. Stimulation of inositol 1,4,5-trisphosphate (IP3) receptor subtypes by analogues of IP3. Plos One. 8: e54877. PMID 23372785 DOI: 10.1371/Journal.Pone.0054877  0.603
2013 Khan SA, Rossi AM, Riley AM, Potter BV, Taylor CW. Subtype-selective regulation of IP(3) receptors by thimerosal via cysteine residues within the IP(3)-binding core and suppressor domain. The Biochemical Journal. 451: 177-84. PMID 23282150 DOI: 10.1042/Bj20121600  0.596
2013 Veiga N, Torres J, Macho I, Gómez K, Godage HY, Riley AM, Potter BV, González G, Kremer C. Inframolecular acid-base and coordination properties towards Na(+) and Mg(2+) of myo-inositol 1,3,4,5,6-pentakisphosphate: a structural approach to biologically relevant species. Dalton Transactions (Cambridge, England : 2003). 42: 6021-32. PMID 23183928 DOI: 10.1039/C2Dt31807E  0.594
2012 Mills SJ, Luyten T, Erneux C, Parys JB, Potter BV. Multivalent benzene polyphosphate derivatives are non-Ca(2+)-mobilizing Ins(1,4,5)P3 receptor antagonists. Messenger (Los Angeles, Calif. : Print). 1: 167-181. PMID 24749014 DOI: 10.1166/Msr.2012.1016  0.656
2012 Grint T, Riley AM, Mills SJ, Potter BV, Safrany ST. Fibrinogen - a possible extracellular target for inositol phosphates. Messenger (Los Angeles, Calif. : Print). 1: 160-166. PMID 24749013 DOI: 10.1166/Msr.2012.1014  0.72
2012 Su X, Halem HA, Thomas MP, Moutrille C, Culler MD, Vicker N, Potter BV. Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors. Bioorganic & Medicinal Chemistry. 20: 6394-402. PMID 23040895 DOI: 10.1016/J.Bmc.2012.08.056  0.695
2012 Riley AM, Wang H, Weaver JD, Shears SB, Potter BV. First synthetic analogues of diphosphoinositol polyphosphates: interaction with PP-InsP5 kinase. Chemical Communications (Cambridge, England). 48: 11292-4. PMID 23032903 DOI: 10.1039/C2Cc36044F  0.597
2012 Turner BL, Cheesman AW, Godage HY, Riley AM, Potter BV. Determination of neo- and D-chiro-inositol hexakisphosphate in soils by solution 31P NMR spectroscopy. Environmental Science & Technology. 46: 4994-5002. PMID 22489788 DOI: 10.1021/Es204446Z  0.581
2012 Mills SJ, Persson C, Cozier G, Thomas MP, Trésaugues L, Erneux C, Riley AM, Nordlund P, Potter BV. A synthetic polyphosphoinositide headgroup surrogate in complex with SHIP2 provides a rationale for drug discovery. Acs Chemical Biology. 7: 822-8. PMID 22330088 DOI: 10.1021/Cb200494D  0.723
2012 Swarbrick JM, Potter BV. Total synthesis of a cyclic adenosine 5'-diphosphate ribose receptor agonist. The Journal of Organic Chemistry. 77: 4191-7. PMID 22283398 DOI: 10.1021/Jo202319F  0.365
2012 Moreau C, Kirchberger T, Zhang B, Thomas MP, Weber K, Guse AH, Potter BV. Aberrant cyclization affords a C-6 modified cyclic adenosine 5'-diphosphoribose analogue with biological activity in Jurkat T cells. Journal of Medicinal Chemistry. 55: 1478-89. PMID 22248391 DOI: 10.1021/Jm201127Y  0.32
2012 Sureshan KM, Riley AM, Thomas MP, Tovey SC, Taylor CW, Potter BV. Contribution of phosphates and adenine to the potency of adenophostins at the IP₃ receptor: synthesis of all possible bisphosphates of adenophostin A. Journal of Medicinal Chemistry. 55: 1706-20. PMID 22248345 DOI: 10.1021/Jm201571P  0.737
2012 Leese MP, Jourdan F, Dohle W, Kimberley MR, Thomas MP, Bai R, Hamel E, Ferrandis E, Potter BV. Steroidomimetic Tetrahydroisoquinolines for the Design of New Microtubule Disruptors. Acs Medicinal Chemistry Letters. 3: 5-9. PMID 22247790 DOI: 10.1021/Ml200232C  0.66
2012 Liu C, Potter BV. Synthesis of 3-Position-Modified Analogues of myo-Inositol 1,4,5-Trisphosphate, Tools for Investigation of the Polyphosphoinositide Pathway of Cellular Signaling. The Journal of Organic Chemistry. 62: 8335-40. PMID 11671970 DOI: 10.1021/Jo970926Y  0.302
2011 Woo LW, Bubert C, Purohit A, Potter BV. Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity. Acs Medicinal Chemistry Letters. 2: 243-7. PMID 24900302 DOI: 10.1021/Ml100273K  0.345
2011 Woo LW, Ganeshapillai D, Thomas MP, Sutcliffe OB, Malini B, Mahon MF, Purohit A, Potter BV. Structure-activity relationship for the first-in-class clinical steroid sulfatase inhibitor Irosustat (STX64, BN83495). Chemmedchem. 6: 2019-34. PMID 21990014 DOI: 10.1002/Cmdc.201100288  0.369
2011 Su X, Pradaux-Caggiano F, Vicker N, Thomas MP, Halem H, Culler MD, Potter BV. Adamantyl ethanone pyridyl derivatives: potent and selective inhibitors of human 11β-hydroxysteroid dehydrogenase type 1. Chemmedchem. 6: 1616-29. PMID 21714097 DOI: 10.1002/Cmdc.201100182  0.681
2011 Purohit A, Woo LW, Potter BV. Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism. Molecular and Cellular Endocrinology. 340: 154-60. PMID 21693170 DOI: 10.1016/J.Mce.2011.06.012  0.316
2011 Wood PM, Woo LW, Thomas MP, Mahon MF, Purohit A, Potter BV. Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates. Chemmedchem. 6: 1423-38. PMID 21608133 DOI: 10.1002/Cmdc.201100145  0.388
2011 Su X, Vicker N, Thomas MP, Pradaux-Caggiano F, Halem H, Culler MD, Potter BV. Discovery of adamantyl heterocyclic ketones as potent 11β-hydroxysteroid dehydrogenase type 1 inhibitors. Chemmedchem. 6: 1439-51. PMID 21608132 DOI: 10.1002/Cmdc.201100144  0.679
2011 Jourdan F, Leese MP, Dohle W, Ferrandis E, Newman SP, Chander S, Purohit A, Potter BV. Structure-activity relationships of C-17-substituted estratriene-3-O-sulfamates as anticancer agents. Journal of Medicinal Chemistry. 54: 4863-79. PMID 21604672 DOI: 10.1021/Jm200483X  0.679
2011 Woo LW, Purohit A, Potter BV. Development of steroid sulfatase inhibitors. Molecular and Cellular Endocrinology. 340: 175-85. PMID 21238537 DOI: 10.1016/J.Mce.2010.12.035  0.317
2011 Moreau C, Ashamu GA, Bailey VC, Galione A, Guse AH, Potter BV. Synthesis of cyclic adenosine 5'-diphosphate ribose analogues: a C2'endo/syn "southern" ribose conformation underlies activity at the sea urchin cADPR receptor. Organic & Biomolecular Chemistry. 9: 278-90. PMID 20976353 DOI: 10.1039/C0Ob00396D  0.366
2010 Rossi AM, Riley AM, Potter BV, Taylor CW. Adenophostins: High-Affinity Agonists of IP(3) Receptors. Current Topics in Membranes. 66: 209-33. PMID 22353482 DOI: 10.1016/S1063-5823(10)66010-3  0.61
2010 Wood PM, Woo LW, Labrosse JR, Thomas MP, Mahon MF, Chander SK, Purohit A, Reed MJ, Potter BV. Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{[(4-cyanophenyl)(4h-1,2,4-triazol-4-yl)amino]methyl}phenylsulfamate: synthesis, SAR, crystal structure, and in vitro and in vivo activities. Chemmedchem. 5: 1577-93. PMID 20632362 DOI: 10.1002/Cmdc.201000203  0.366
2010 Su X, Pradaux-Caggiano F, Thomas MP, Szeto MW, Halem HA, Culler MD, Vicker N, Potter BV. Discovery of adamantyl ethanone derivatives as potent 11beta-hydroxysteroid dehydrogenase type 1 (11beta-HSD1) inhibitors. Chemmedchem. 5: 1026-44. PMID 20486152 DOI: 10.1002/Cmdc.201000081  0.7
2010 Cozier GE, Leese MP, Lloyd MD, Baker MD, Thiyagarajan N, Acharya KR, Potter BV. Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors. Biochemistry. 49: 3464-76. PMID 20297840 DOI: 10.1021/Bi902178W  0.376
2010 Jourdan F, Leese MP, Dohle W, Hamel E, Ferrandis E, Newman SP, Purohit A, Reed MJ, Potter BV. Synthesis, antitubulin, and antiproliferative SAR of analogues of 2-methoxyestradiol-3,17-O,O-bis-sulfamate. Journal of Medicinal Chemistry. 53: 2942-51. PMID 20225862 DOI: 10.1021/Jm9018806  0.677
2010 Ding Z, Rossi AM, Riley AM, Rahman T, Potter BV, Taylor CW. Binding of inositol 1,4,5-trisphosphate (IP3) and adenophostin A to the N-terminal region of the IP3 receptor: thermodynamic analysis using fluorescence polarization with a novel IP3 receptor ligand. Molecular Pharmacology. 77: 995-1004. PMID 20215561 DOI: 10.1124/Mol.109.062596  0.604
2010 Woo LW, Jackson T, Putey A, Cozier G, Leonard P, Acharya KR, Chander SK, Purohit A, Reed MJ, Potter BV. Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template. Journal of Medicinal Chemistry. 53: 2155-70. PMID 20148564 DOI: 10.1021/Jm901705H  0.358
2009 Rossi AM, Riley AM, Tovey SC, Rahman T, Dellis O, Taylor EJ, Veresov VG, Potter BV, Taylor CW. Synthetic partial agonists reveal key steps in IP3 receptor activation. Nature Chemical Biology. 5: 631-9. PMID 19668195 DOI: 10.1038/Nchembio.195  0.62
2009 Dammermann W, Zhang B, Nebel M, Cordiglieri C, Odoardi F, Kirchberger T, Kawakami N, Dowden J, Schmid F, Dornmair K, Hohenegger M, Flügel A, Guse AH, Potter BV. NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist. Proceedings of the National Academy of Sciences of the United States of America. 106: 10678-83. PMID 19541638 DOI: 10.1073/Pnas.0809997106  0.329
2009 Kirchberger T, Moreau C, Wagner GK, Fliegert R, Siebrands CC, Nebel M, Schmid F, Harneit A, Odoardi F, Flügel A, Potter BV, Guse AH. 8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist. The Biochemical Journal. 422: 139-49. PMID 19492987 DOI: 10.1042/Bj20082308  0.577
2009 Veiga N, Torres J, Godage HY, Riley AM, Domínguez S, Potter BV, Díaz A, Kremer C. The behaviour of inositol 1,3,4,5,6-pentakisphosphate in the presence of the major biological metal cations. Journal of Biological Inorganic Chemistry : Jbic : a Publication of the Society of Biological Inorganic Chemistry. 14: 1001-13. PMID 19415348 DOI: 10.1007/S00775-009-0510-Z  0.6
2009 Day JM, Purohit A, Tutill HJ, Foster PA, Woo LW, Potter BV, Reed MJ. The development of steroid sulfatase inhibitors for hormone-dependent cancer therapy. Annals of the New York Academy of Sciences. 1155: 80-7. PMID 19250195 DOI: 10.1111/J.1749-6632.2008.03677.X  0.313
2009 Sureshan KM, Riley AM, Rossi AM, Tovey SC, Dedos SG, Taylor CW, Potter BV. Activation of IP(3) receptors by synthetic bisphosphate ligands. Chemical Communications (Cambridge, England). 1204-6. PMID 19240874 DOI: 10.1039/B819328B  0.742
2009 Day JM, Tutill HJ, Foster PA, Bailey HV, Heaton WB, Sharland CM, Vicker N, Potter BV, Purohit A, Reed MJ. Development of hormone-dependent prostate cancer models for the evaluation of inhibitors of 17beta-hydroxysteroid dehydrogenase type 3. Molecular and Cellular Endocrinology. 301: 251-8. PMID 18786604 DOI: 10.1016/J.Mce.2008.08.014  0.32
2009 Su X, Vicker N, Trusselle M, Halem H, Culler MD, Potter BV. Discovery of novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology. 301: 169-73. PMID 18775471 DOI: 10.1016/J.Mce.2008.08.006  0.692
2009 Vicker N, Sharland CM, Heaton WB, Gonzalez AM, Bailey HV, Smith A, Springall JS, Day JM, Tutill HJ, Reed MJ, Purohit A, Potter BV. The design of novel 17beta-hydroxysteroid dehydrogenase type 3 inhibitors. Molecular and Cellular Endocrinology. 301: 259-65. PMID 18775469 DOI: 10.1016/J.Mce.2008.08.005  0.34
2009 Rossi AM, Riley A, Tovey SC, Dellis O, Potter BV, Taylor CW. Analysis of IP3 Receptor Activation Using Novel Partial Agonists Biophysical Journal. 96: 486a. DOI: 10.1016/J.Bpj.2008.12.2509  0.619
2008 Tagg SL, Foster PA, Leese MP, Potter BV, Reed MJ, Purohit A, Newman SP. 2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer. British Journal of Cancer. 99: 1842-8. PMID 18985042 DOI: 10.1038/Sj.Bjc.6604752  0.337
2008 Jourdan F, Bubert C, Leese MP, Smith A, Ferrandis E, Regis-Lydi S, Newman SP, Purohit A, Reed MJ, Potter BV. Effects of C-17 heterocyclic substituents on the anticancer activity of 2-ethylestra-1,3,5(10)-triene-3-O-sulfamates: synthesis, in vitro evaluation and computational modelling. Organic & Biomolecular Chemistry. 6: 4108-19. PMID 18972041 DOI: 10.1039/B810300C  0.39
2008 Foster PA, Chander SK, Newman SP, Woo LW, Sutcliffe OB, Bubert C, Zhou D, Chen S, Potter BV, Reed MJ, Purohit A. A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 6469-77. PMID 18927286 DOI: 10.1158/1078-0432.Ccr-08-1027  0.317
2008 Parsons MF, Foster PA, Chander SK, Jhalli R, Newman SP, Leese MP, Potter BV, Purohit A, Reed MJ. The in vivo properties of STX243: a potent angiogenesis inhibitor in breast cancer. British Journal of Cancer. 99: 1433-41. PMID 18841154 DOI: 10.1038/Sj.Bjc.6604707  0.336
2008 Woo LW, Fischer DS, Sharland CM, Trusselle M, Foster PA, Chander SK, Di Fiore A, Supuran CT, De Simone G, Purohit A, Reed MJ, Potter BV. Anticancer steroid sulfatase inhibitors: synthesis of a potent fluorinated second-generation agent, in vitro and in vivo activities, molecular modeling, and protein crystallography. Molecular Cancer Therapeutics. 7: 2435-44. PMID 18723489 DOI: 10.1158/1535-7163.Mct-08-0195  0.397
2008 Wood PM, Woo LW, Labrosse JR, Trusselle MN, Abbate S, Longhi G, Castiglioni E, Lebon F, Purohit A, Reed MJ, Potter BV. Chiral aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole template: synthesis, absolute configuration, and in vitro activity. Journal of Medicinal Chemistry. 51: 4226-38. PMID 18590272 DOI: 10.1021/Jm800168S  0.364
2008 Su X, Vicker N, Potter BV. Inhibitors of 11beta-hydroxysteroid dehydrogenase type 1. Progress in Medicinal Chemistry. 46: 29-130. PMID 18381124 DOI: 10.1016/S0079-6468(07)00002-1  0.639
2008 Allan GM, Vicker N, Lawrence HR, Tutill HJ, Day JM, Huchet M, Ferrandis E, Reed MJ, Purohit A, Potter BV. Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: templates for design. Bioorganic & Medicinal Chemistry. 16: 4438-56. PMID 18329273 DOI: 10.1016/J.Bmc.2008.02.059  0.336
2008 Zhang B, Wagner GK, Weber K, Garnham C, Morgan AJ, Galione A, Guse AH, Potter BV. 2'-deoxy cyclic adenosine 5'-diphosphate ribose derivatives: importance of the 2'-hydroxyl motif for the antagonistic activity of 8-substituted cADPR derivatives. Journal of Medicinal Chemistry. 51: 1623-36. PMID 18303825 DOI: 10.1021/Jm7010386  0.626
2008 Leese MP, Jourdan FL, Gaukroger K, Mahon MF, Newman SP, Foster PA, Stengel C, Regis-Lydi S, Ferrandis E, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. Structure-activity relationships of C-17 cyano-substituted estratrienes as anticancer agents. Journal of Medicinal Chemistry. 51: 1295-308. PMID 18260615 DOI: 10.1021/Jm701319C  0.377
2008 Sureshan KM, Trusselle M, Tovey SC, Taylor CW, Potter BV. 2-Position base-modified analogues of adenophostin A as high-affinity agonists of the D-myo-inositol trisphosphate receptor: in vitro evaluation and molecular modeling. The Journal of Organic Chemistry. 73: 1682-92. PMID 18247493 DOI: 10.1021/Jo702617C  0.653
2008 Zhang B, Bailey VC, Potter BV. Chemoenzymatic synthesis of 7-deaza cyclic adenosine 5'-diphosphate ribose analogues, membrane-permeant modulators of intracellular calcium release. The Journal of Organic Chemistry. 73: 1693-703. PMID 18229937 DOI: 10.1021/Jo071236P  0.345
2008 Day JM, Foster PA, Tutill HJ, Parsons MF, Newman SP, Chander SK, Allan GM, Lawrence HR, Vicker N, Potter BV, Reed MJ, Purohit A. 17beta-hydroxysteroid dehydrogenase Type 1, and not Type 12, is a target for endocrine therapy of hormone-dependent breast cancer. International Journal of Cancer. Journal International Du Cancer. 122: 1931-40. PMID 18183589 DOI: 10.1002/Ijc.23350  0.302
2008 Foster PA, Ho YT, Newman SP, Kasprzyk PG, Leese MP, Potter BV, Reed MJ, Purohit A. 2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique. Breast Cancer Research and Treatment. 111: 251-60. PMID 17957467 DOI: 10.1007/S10549-007-9791-5  0.309
2008 Foster PA, Chander SK, Parsons MF, Newman SP, Woo LW, Potter BV, Reed MJ, Purohit A. Efficacy of three potent steroid sulfatase inhibitors: pre-clinical investigations for their use in the treatment of hormone-dependent breast cancer. Breast Cancer Research and Treatment. 111: 129-38. PMID 17914670 DOI: 10.1007/S10549-007-9769-3  0.311
2007 Woo LW, Bubert C, Sutcliffe OB, Smith A, Chander SK, Mahon MF, Purohit A, Reed MJ, Potter BV. Dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry. 50: 3540-60. PMID 17580845 DOI: 10.1021/Jm061462B  0.338
2007 Su X, Vicker N, Lawrence H, Smith A, Purohit A, Reed MJ, Potter BV. Inhibition of human and rat 11beta-hydroxysteroid dehydrogenase type 1 by 18beta-glycyrrhetinic acid derivatives. The Journal of Steroid Biochemistry and Molecular Biology. 104: 312-20. PMID 17493801 DOI: 10.1016/J.Jsbmb.2007.03.019  0.674
2007 Vicker N, Su X, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. The Journal of Steroid Biochemistry and Molecular Biology. 104: 123-9. PMID 17482805 DOI: 10.1016/J.Jsbmb.2007.03.023  0.681
2007 Zhang B, Muller-Steffner H, Schuber F, Potter BV. Nicotinamide 2-fluoroadenine dinucleotide unmasks the NAD+ glycohydrolase activity of Aplysia californica adenosine 5'-diphosphate ribosyl cyclase. Biochemistry. 46: 4100-9. PMID 17341094 DOI: 10.1021/Bi061933W  0.357
2007 Vandeput F, Combettes L, Mills SJ, Backers K, Wohlkönig A, Parys JB, De Smedt H, Missiaen L, Dupont G, Potter BV, Erneux C. Biphenyl 2,3',4,5',6-pentakisphosphate, a novel inositol polyphosphate surrogate, modulates Ca2+ responses in rat hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 21: 1481-91. PMID 17264160 DOI: 10.1096/Fj.06-7691Com  0.649
2007 Sureshan KM, Riley AM, Potter BV. Rapid and efficient routes to phosphatidylinositol 3,4,5-trisphosphates via myo-inositol orthobenzoate Tetrahedron Letters. 48: 1923-1926. DOI: 10.1016/J.Tetlet.2007.01.095  0.717
2006 Leese MP, Leblond B, Smith A, Newman SP, Di Fiore A, De Simone G, Supuran CT, Purohit A, Reed MJ, Potter BV. 2-substituted estradiol bis-sulfamates, multitargeted antitumor agents: synthesis, in vitro SAR, protein crystallography, and in vivo activity. Journal of Medicinal Chemistry. 49: 7683-96. PMID 17181151 DOI: 10.1021/Jm060705X  0.36
2006 Foster PA, Newman SP, Chander SK, Stengel C, Jhalli R, Woo LL, Potter BV, Reed MJ, Purohit A. In vivo efficacy of STX213, a second-generation steroid sulfatase inhibitor, for hormone-dependent breast cancer therapy. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 5543-9. PMID 17000691 DOI: 10.1158/1078-0432.Ccr-06-0632  0.768
2006 Mochizuki T, Kondo Y, Abe H, Tovey SC, Dedos SG, Taylor CW, Paul M, Potter BV, Matsuda A, Shuto S. Synthesis of adenophostin A analogues conjugating an aromatic group at the 5'-position as potent IP3 receptor ligands. Journal of Medicinal Chemistry. 49: 5750-8. PMID 16970399 DOI: 10.1021/Jm060310D  0.374
2006 Kirchberger T, Wagner G, Xu J, Cordiglieri C, Wang P, Gasser A, Fliegert R, Bruhn S, Flügel A, Lund FE, Zhang LH, Potter BV, Guse AH. Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives. British Journal of Pharmacology. 149: 337-44. PMID 16967053 DOI: 10.1038/Sj.Bjp.0706869  0.566
2006 Mills SJ, Dozol H, Vandeput F, Backers K, Woodman T, Erneux C, Spiess B, Potter BV. 3-hydroxybenzene 1,2,4-trisphosphate, a novel second messenger mimic and unusual substrate for type-I myo-inositol 1,4,5-trisphosphate 5-phosphatase: Synthesis and physicochemistry. Chembiochem : a European Journal of Chemical Biology. 7: 1696-706. PMID 16964627 DOI: 10.1002/Cbic.200600125  0.599
2006 Moreau C, Wagner GK, Weber K, Guse AH, Potter BV. Structural determinants for N1/N7 cyclization of nicotinamide hypoxanthine 5'-dinucleotide (NHD+) derivatives by ADP-ribosyl cyclase from aplysia californica: Ca2+-mobilizing activity of 8-substituted cyclic inosine 5'-diphosphoribose analogues in T-lymphocytes. Journal of Medicinal Chemistry. 49: 5162-76. PMID 16913705 DOI: 10.1021/Jm060275A  0.591
2006 Vicker N, Lawrence HR, Allan GM, Bubert C, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Focused libraries of 16-substituted estrone derivatives and modified e-ring steroids: inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. Chemmedchem. 1: 464-81. PMID 16892382 DOI: 10.1002/Cmdc.200500087  0.377
2006 Godage HY, Riley AM, Woodman TJ, Potter BV. Regioselective hydrolysis of myo-inositol 1,3,5-orthobenzoate via a 1,2-bridged 2'-phenyl-1',3'-dioxolan-2'-ylium ion provides a rapid route to the anticancer agent Ins(1,3,4,5,6)P5. Chemical Communications (Cambridge, England). 2989-91. PMID 16832513 DOI: 10.1039/B605392K  0.59
2006 Dowden J, Berridge G, Moreau C, Yamasaki M, Churchill GC, Potter BV, Galione A. Cell-permeant small-molecule modulators of NAADP-mediated Ca2+ release. Chemistry & Biology. 13: 659-65. PMID 16793523 DOI: 10.1016/J.Chembiol.2006.05.005  0.365
2006 Sureshan KM, Trusselle M, Tovey SC, Taylor CW, Potter BV. Guanophostin A: Synthesis and evaluation of a high affinity agonist of the D-myo-inositol 1,4,5-trisphosphate receptor. Chemical Communications (Cambridge, England). 2015-7. PMID 16767260 DOI: 10.1039/B517911D  0.627
2006 Riley AM, Trusselle M, Kuad P, Borkovec M, Cho J, Choi JH, Qian X, Shears SB, Spiess B, Potter BV. scyllo-inositol pentakisphosphate as an analogue of myo-inositol 1,3,4,5,6-pentakisphosphate: chemical synthesis, physicochemistry and biological applications. Chembiochem : a European Journal of Chemical Biology. 7: 1114-22. PMID 16755629 DOI: 10.1002/Cbic.200600037  0.62
2006 Mochizuki T, Kondo Y, Abe H, Taylor CW, Potter BV, Matsuda A, Shuto S. Design and synthesis of 5'-deoxy-5'-phenyladenophostin A, a highly potent IP3 receptor ligand. Organic Letters. 8: 1455-8. PMID 16562915 DOI: 10.1021/Ol0602710  0.34
2006 Terauchi M, Abe H, Tovey SC, Dedos SG, Taylor CW, Paul M, Trusselle M, Potter BV, Matsuda A, Shuto S. A systematic study of C-glucoside trisphosphates as myo-inositol trisphosphate receptor ligands. Synthesis of beta-C-glucoside trisphosphates based on the conformational restriction strategy. Journal of Medicinal Chemistry. 49: 1900-9. PMID 16539376 DOI: 10.1021/Jm051039N  0.314
2006 Stanway SJ, Purohit A, Woo LW, Sufi S, Vigushin D, Ward R, Wilson RH, Stanczyk FZ, Dobbs N, Kulinskaya E, Elliott M, Potter BV, Reed MJ, Coombes RC. Phase I study of STX 64 (667 Coumate) in breast cancer patients: the first study of a steroid sulfatase inhibitor. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 1585-92. PMID 16533785 DOI: 10.1158/1078-0432.Ccr-05-1996  0.3
2006 Allan GM, Lawrence HR, Cornet J, Bubert C, Fischer DS, Vicker N, Smith A, Tutill HJ, Purohit A, Day JM, Mahon MF, Reed MJ, Potter BV. Modification of estrone at the 6, 16, and 17 positions: novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. Journal of Medicinal Chemistry. 49: 1325-45. PMID 16480268 DOI: 10.1021/Jm050830T  0.336
2006 Purohit A, Tutill HJ, Day JM, Chander SK, Lawrence HR, Allan GM, Fischer DS, Vicker N, Newman SP, Potter BV, Reed MJ. The regulation and inhibition of 17beta-hydroxysteroid dehydrogenase in breast cancer. Molecular and Cellular Endocrinology. 248: 199-203. PMID 16414180 DOI: 10.1016/J.Mce.2005.12.003  0.309
2006 Newman SP, Ireson CR, Tutill HJ, Day JM, Parsons MF, Leese MP, Potter BV, Reed MJ, Purohit A. The role of 17beta-hydroxysteroid dehydrogenases in modulating the activity of 2-methoxyestradiol in breast cancer cells. Cancer Research. 66: 324-30. PMID 16397246 DOI: 10.1158/0008-5472.Can-05-2391  0.321
2006 Riley AM, Deleu S, Qian X, Mitchell J, Chung SK, Adelt S, Vogel G, Potter BV, Shears SB. On the contribution of stereochemistry to human ITPK1 specificity: Ins(1,4,5,6)P4 is not a physiologic substrate. Febs Letters. 580: 324-30. PMID 16376887 DOI: 10.1016/J.Febslet.2005.12.016  0.615
2006 Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Reed MJ, Potter BV. Novel, potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology. 248: 204-7. PMID 16337736 DOI: 10.1016/J.Mce.2005.10.021  0.36
2006 Su X, Vicker N, Ganeshapillai D, Smith A, Purohit A, Reed MJ, Potter BV. Benzothiazole derivatives as novel inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. Molecular and Cellular Endocrinology. 248: 214-7. PMID 16325333 DOI: 10.1016/J.Mce.2005.10.022  0.692
2006 Riley AM, Godage HY, Mahon MF, Potter BV. Chiral desymmetrisation of myo-inositol 1,3,5-orthobenzoate gives rapid access to precursors for second messenger analogues Tetrahedron: Asymmetry. 17: 171-174. DOI: 10.1016/J.Tetasy.2005.12.008  0.592
2005 Dowden J, Brown RS, Moreau C, Galione A, Potter BV. Chemical synthesis of the novel Ca2+ messenger NAADP. Nucleosides, Nucleotides & Nucleic Acids. 24: 513-8. PMID 16247981 DOI: 10.1081/Ncn-200061786  0.36
2005 Maffucci T, Piccolo E, Cumashi A, Iezzi M, Riley AM, Saiardi A, Godage HY, Rossi C, Broggini M, Iacobelli S, Potter BV, Innocenti P, Falasca M. Inhibition of the phosphatidylinositol 3-kinase/Akt pathway by inositol pentakisphosphate results in antiangiogenic and antitumor effects. Cancer Research. 65: 8339-49. PMID 16166311 DOI: 10.1158/0008-5472.Can-05-0121  0.613
2005 Fischer DS, Allan GM, Bubert C, Vicker N, Smith A, Tutill HJ, Purohit A, Wood L, Packham G, Mahon MF, Reed MJ, Potter BV. E-ring modified steroids as novel potent inhibitors of 17beta-hydroxysteroid dehydrogenase type 1. Journal of Medicinal Chemistry. 48: 5749-70. PMID 16134943 DOI: 10.1021/Jm050348A  0.384
2005 Leese MP, Hejaz HA, Mahon MF, Newman SP, Purohit A, Reed MJ, Potter BV. A-ring-substituted estrogen-3-O-sulfamates: potent multitargeted anticancer agents. Journal of Medicinal Chemistry. 48: 5243-56. PMID 16078843 DOI: 10.1021/Jm050066A  0.381
2005 Poinas A, Backers K, Riley AM, Mills SJ, Moreau C, Potter BV, Erneux C. Interaction of the catalytic domain of inositol 1,4,5-trisphosphate 3-kinase A with inositol phosphate analogues. Chembiochem : a European Journal of Chemical Biology. 6: 1449-57. PMID 15997461 DOI: 10.1002/Cbic.200400443  0.732
2005 Laude AJ, Tovey SC, Dedos SG, Potter BV, Lummis SC, Taylor CW. Rapid functional assays of recombinant IP3 receptors. Cell Calcium. 38: 45-51. PMID 15963563 DOI: 10.1016/J.Ceca.2005.04.001  0.318
2005 Kudoh T, Fukuoka M, Ichikawa S, Murayama T, Ogawa Y, Hashii M, Higashida H, Kunerth S, Weber K, Guse AH, Potter BV, Matsuda A, Shuto S. Synthesis of stable and cell-type selective analogues of cyclic ADP-ribose, a Ca(2+)-mobilizing second messenger. Structure--activity relationship of the N1-ribose moiety. Journal of the American Chemical Society. 127: 8846-55. PMID 15954793 DOI: 10.1021/Ja050732X  0.372
2005 Wagner GK, Guse AH, Potter BV. Rapid synthetic route toward structurally modified derivatives of cyclic adenosine 5'-diphosphate ribose. The Journal of Organic Chemistry. 70: 4810-9. PMID 15932322 DOI: 10.1021/Jo050085S  0.578
2005 Raobaikady B, Reed MJ, Leese MP, Potter BV, Purohit A. Inhibition of MDA-MB-231 cell cycle progression and cell proliferation by C-2-substituted oestradiol mono- and bis-3-O-sulphamates. International Journal of Cancer. 117: 150-9. PMID 15880363 DOI: 10.1002/Ijc.21066  0.339
2005 Lloyd MD, Thiyagarajan N, Ho YT, Woo LW, Sutcliffe OB, Purohit A, Reed MJ, Acharya KR, Potter BV. First crystal structures of human carbonic anhydrase II in complex with dual aromatase-steroid sulfatase inhibitors. Biochemistry. 44: 6858-66. PMID 15865431 DOI: 10.1021/Bi047692E  0.382
2005 Leese MP, Leblond B, Newman SP, Purohit A, Reed MJ, Potter BV. Anti-cancer activities of novel D-ring modified 2-substituted estrogen-3-O-sulfamates. The Journal of Steroid Biochemistry and Molecular Biology. 94: 239-51. PMID 15862971 DOI: 10.1016/J.Jsbmb.2005.01.005  0.387
2005 Raobaikady B, Day JM, Purohit A, Potter BV, Reed MJ. The nature of inhibition of steroid sulphatase activity by tibolone and its metabolites. The Journal of Steroid Biochemistry and Molecular Biology. 94: 229-37. PMID 15862970 DOI: 10.1016/J.Jsbmb.2005.01.021  0.366
2005 Utsumi T, Leese MP, Chander SK, Gaukroger K, Purohit A, Newman SP, Potter BV, Reed MJ. The effects of 2-methoxyoestrogen sulphamates on the in vitro and in vivo proliferation of breast cancer cells. The Journal of Steroid Biochemistry and Molecular Biology. 94: 219-27. PMID 15862969 DOI: 10.1016/J.Jsbmb.2005.01.022  0.354
2005 Purohit A, Ghilchik MW, Leese MP, Potter BV, Reed MJ. Regulation of aromatase activity by cytokines, PGE2 and 2-methoxyoestrone-3-O-sulphamate in fibroblasts derived from normal and malignant breast tissues. The Journal of Steroid Biochemistry and Molecular Biology. 94: 167-72. PMID 15862962 DOI: 10.1016/J.Jsbmb.2005.01.015  0.344
2005 Wood PM, Woo LW, Humphreys A, Chander SK, Purohit A, Reed MJ, Potter BV. A letrozole-based dual aromatase-sulphatase inhibitor with in vivo activity. The Journal of Steroid Biochemistry and Molecular Biology. 94: 123-30. PMID 15862957 DOI: 10.1016/J.Jsbmb.2004.12.028  0.353
2005 Lawrence HR, Vicker N, Allan GM, Smith A, Mahon MF, Tutill HJ, Purohit A, Reed MJ, Potter BV. Novel and potent 17beta-hydroxysteroid dehydrogenase type 1 inhibitors. Journal of Medicinal Chemistry. 48: 2759-62. PMID 15828812 DOI: 10.1021/Jm049045R  0.315
2005 Borissow CN, Black SJ, Paul M, Tovey SC, Dedos SG, Taylor CW, Potter BV. Adenophostin A and analogues modified at the adenine moiety: synthesis, conformational analysis and biological activity. Organic & Biomolecular Chemistry. 3: 245-52. PMID 15632966 DOI: 10.1039/B415229H  0.401
2005 Reed MJ, Purohit A, Woo LW, Newman SP, Potter BV. Steroid sulfatase: molecular biology, regulation, and inhibition. Endocrine Reviews. 26: 171-202. PMID 15561802 DOI: 10.1210/Er.2004-0003  0.33
2005 Lloyd MD, Pederick RL, Natesh R, Woo LW, Purohit A, Reed MJ, Acharya KR, Potter BV. Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agent. The Biochemical Journal. 385: 715-20. PMID 15453828 DOI: 10.1042/Bj20041037  0.368
2005 Terauchi M, Yahiro Y, Abe H, Ichikawa S, Tovey SC, Dedos SG, Taylor CW, Potter BV, Matsuda A, Shuto S. Synthesis of 4,8-anhydro-d-glycero-d-ido-nonanitol 1,6,7-trisphosphate as a novel IP3 receptor ligand using a stereoselective radical cyclization reaction based on a conformational restriction strategy Tetrahedron. 61: 3697-3707. DOI: 10.1016/J.Tet.2005.02.025  0.35
2004 Ireson CR, Chander SK, Purohit A, Parish DC, Woo LW, Potter BV, Reed MJ. Pharmacokinetics of the nonsteroidal steroid sulphatase inhibitor 667 COUMATE and its sequestration into red blood cells in rats. British Journal of Cancer. 91: 1399-404. PMID 15328524 DOI: 10.1038/Sj.Bjc.6602130  0.327
2004 Chander SK, Purohit A, Woo LW, Potter BV, Reed MJ. The role of steroid sulphatase in regulating the oestrogenicity of oestrogen sulphamates. Biochemical and Biophysical Research Communications. 322: 217-22. PMID 15313194 DOI: 10.1016/J.Bbrc.2004.07.108  0.309
2004 Solyakov L, Cain K, Tracey BM, Jukes R, Riley AM, Potter BV, Tobin AB. Regulation of casein kinase-2 (CK2) activity by inositol phosphates. The Journal of Biological Chemistry. 279: 43403-10. PMID 15297462 DOI: 10.1074/Jbc.M403239200  0.587
2004 Su X, Lawrence H, Ganeshapillai D, Cruttenden A, Purohit A, Reed MJ, Vicker N, Potter BV. Novel 18beta-glycyrrhetinic acid analogues as potent and selective inhibitors of 11beta-hydroxysteroid dehydrogenases. Bioorganic & Medicinal Chemistry. 12: 4439-57. PMID 15265495 DOI: 10.1016/J.Bmc.2004.06.008  0.673
2004 Horne G, Maechling C, Fleig A, Hirata M, Penner R, Spiess B, Potter BV. D-6-Deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, a mimic of d-myo-inositol 1,3,4,5-tetrakisphosphate: biological activity and pH-dependent conformational properties. Biochemical and Biophysical Research Communications. 320: 1262-70. PMID 15249226 DOI: 10.1016/J.Bbrc.2004.06.079  0.371
2004 Gregory RB, Hughes R, Riley AM, Potter BV, Wilcox RA, Barritt GJ. Inositol trisphosphate analogues selective for types I and II inositol trisphosphate receptors exert differential effects on vasopressin-stimulated Ca2+ inflow and Ca2+ release from intracellular stores in rat hepatocytes. The Biochemical Journal. 381: 519-26. PMID 15169542 DOI: 10.1042/Bj20040637  0.628
2004 Vicker N, Su X, Lawrence H, Cruttenden A, Purohit A, Reed MJ, Potter BV. A novel 18 beta-glycyrrhetinic acid analogue as a potent and selective inhibitor of 11 beta-hydroxysteroid dehydrogenase 2. Bioorganic & Medicinal Chemistry Letters. 14: 3263-7. PMID 15149687 DOI: 10.1016/J.Bmcl.2004.03.107  0.675
2004 Leese MP, Newman SP, Purohit A, Reed MJ, Potter BV. 2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents. Bioorganic & Medicinal Chemistry Letters. 14: 3135-8. PMID 15149660 DOI: 10.1016/J.Bmcl.2004.04.027  0.335
2004 Riley AM, Dozol H, Spiess B, Potter BV. 2-O-(2-Aminoethyl)-myo-inositol 1,4,5-trisphosphate as a novel ligand for conjugation: physicochemical properties and synthesis of a new Ins(1,4,5)P(3) affinity matrix. Biochemical and Biophysical Research Communications. 318: 444-52. PMID 15120621 DOI: 10.1016/J.Bbrc.2004.04.051  0.644
2004 Hejaz HA, Woo LW, Purohit A, Reed MJ, Potter BV. Synthesis, in vitro and in vivo activity of benzophenone-based inhibitors of steroid sulfatase. Bioorganic & Medicinal Chemistry. 12: 2759-72. PMID 15110857 DOI: 10.1016/J.Bmc.2004.02.040  0.415
2004 Potter BV, Walseth TF. Medicinal chemistry and pharmacology of cyclic ADP-ribose. Current Molecular Medicine. 4: 303-11. PMID 15101687 DOI: 10.2174/1566524043360744  0.354
2004 Kunerth S, Langhorst MF, Schwarzmann N, Gu X, Huang L, Yang Z, Zhang L, Mills SJ, Zhang LH, Potter BV, Guse AH. Amplification and propagation of pacemaker Ca2+ signals by cyclic ADP-ribose and the type 3 ryanodine receptor in T cells. Journal of Cell Science. 117: 2141-9. PMID 15054112 DOI: 10.1242/Jcs.01063  0.59
2004 Reed JE, Woo LW, Robinson JJ, Leblond B, Leese MP, Purohit A, Reed MJ, Potter BV. 2-difluoromethyloestrone 3-O-sulphamate, a highly potent steroid sulphatase inhibitor. Biochemical and Biophysical Research Communications. 317: 169-75. PMID 15047163 DOI: 10.1016/J.Bbrc.2004.03.023  0.392
2004 Riley AM, Laude AJ, Taylor CW, Potter BV. Dimers of D-myo-inositol 1,4,5-trisphosphate: design, synthesis, and interaction with Ins(1,4,5)P3 receptors. Bioconjugate Chemistry. 15: 278-89. PMID 15025523 DOI: 10.1021/Bc034214S  0.649
2004 Newman SP, Leese MP, Purohit A, James DR, Rennie CE, Potter BV, Reed MJ. Inhibition of in vitro angiogenesis by 2-methoxy- and 2-ethyl-estrogen sulfamates. International Journal of Cancer. Journal International Du Cancer. 109: 533-40. PMID 14991574 DOI: 10.1002/Ijc.20045  0.339
2004 Piccolo E, Vignati S, Maffucci T, Innominato PF, Riley AM, Potter BV, Pandolfi PP, Broggini M, Iacobelli S, Innocenti P, Falasca M. Inositol pentakisphosphate promotes apoptosis through the PI 3-K/Akt pathway. Oncogene. 23: 1754-65. PMID 14755253 DOI: 10.1038/Sj.Onc.1207296  0.611
2004 Mort CJ, Migaud ME, Galione A, Potter BV. Aplysia californica mediated cyclisation of novel 3'-modified NAD+ analogues: a role for hydrogen bonding in the recognition of cyclic adenosine 5'-diphosphate ribose. Bioorganic & Medicinal Chemistry. 12: 475-87. PMID 14723966 DOI: 10.1016/J.Bmc.2003.10.012  0.592
2004 Abbate F, Winum JY, Potter BV, Casini A, Montero JL, Scozzafava A, Supuran CT. Carbonic anhydrase inhibitors: X-ray crystallographic structure of the adduct of human isozyme II with EMATE, a dual inhibitor of carbonic anhydrases and steroid sulfatase. Bioorganic & Medicinal Chemistry Letters. 14: 231-4. PMID 14684333 DOI: 10.1016/J.Bmcl.2003.09.064  0.352
2004 Horne G, Mills SJ, Potter BV. First derivatives of myo-inositol 1,4,6-trisphosphate modified at positions 2 and 3: structural analogues of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research. 339: 51-65. PMID 14659671 DOI: 10.1016/J.Carres.2003.09.008  0.587
2003 Mills SJ, Riley AM, Liu C, Mahon MF, Potter BV. A definitive synthesis of D-myo-inositol 1,4,5,6-tetrakisphosphate and its enantiomer D-myo-inositol 3,4,5,6-tetrakisphosphate from a novel butane-2,3-diacetal-protected inositol. Chemistry (Weinheim An Der Bergstrasse, Germany). 9: 6207-14. PMID 14679531 DOI: 10.1002/CHIN.200413165  0.703
2003 Purohit A, Woo LW, Chander SK, Newman SP, Ireson C, Ho Y, Grasso A, Leese MP, Potter BV, Reed MJ. Steroid sulphatase inhibitors for breast cancer therapy. The Journal of Steroid Biochemistry and Molecular Biology. 86: 423-32. PMID 14623540 DOI: 10.1016/S0960-0760(03)00353-4  0.392
2003 Mills SJ, Backers K, Erneux C, Potter BV. Synthesis of D- and L-myo-inositol 1,2,4,6-tetrakisphosphate, regioisomers of myo-inositol 1,3,4,5 tetrakisphosphate: activity against Ins(1,4,5)P3 binding proteins. Organic & Biomolecular Chemistry. 1: 3546-56. PMID 14599016 DOI: 10.1039/B302986G  0.634
2003 Rosenberg HJ, Riley AM, Laude AJ, Taylor CW, Potter BV. Synthesis and Ca2+-mobilizing activity of purine-modified mimics of adenophostin A: a model for the adenophostin-Ins(1,4,5)P3 receptor interaction. Journal of Medicinal Chemistry. 46: 4860-71. PMID 14584937 DOI: 10.1021/Jm030883F  0.658
2003 Shuto S, Fukuoka M, Kudoh T, Garnham C, Galione A, Potter BV, Matsuda A. Convergent synthesis and unexpected Ca(2+)-mobilizing activity of 8-substituted analogues of cyclic ADP-carbocyclic-ribose, a stable mimic of the Ca(2+)-mobilizing second messenger cyclic ADP-ribose. Journal of Medicinal Chemistry. 46: 4741-9. PMID 14561093 DOI: 10.1021/Jm030227F  0.403
2003 Wagner GK, Riley AM, Rosenberg HJ, Taylor CW, Guse AH, Potter BV. Analogues of cyclic adenosine 5'-diphosphate ribose and adenophostin A, nucleotides in cellular signal transduction. Nucleic Acids Research. Supplement (2001). 1-2. PMID 14510350  0.723
2003 Mills SJ, Potter BV. Synthesis of potent Ins(1,4,5)P3 5-phosphatase inhibitors by modification of myo-inositol 1,3,4,6-tetrakisphosphate. Bioorganic & Medicinal Chemistry. 11: 4245-53. PMID 12951155 DOI: 10.1016/S0968-0896(03)00347-X  0.659
2003 Wagner GK, Black S, Guse AH, Potter BV. First enzymatic synthesis of an N1-cyclised cADPR (cyclic-ADP ribose) analogue with a hypoxanthine partial structure: discovery of a membrane permeant cADPR agonist. Chemical Communications (Cambridge, England). 1944-5. PMID 12932045 DOI: 10.1039/B305660K  0.567
2003 Whitley P, Reaves BJ, Hashimoto M, Riley AM, Potter BV, Holman GD. Identification of mammalian Vps24p as an effector of phosphatidylinositol 3,5-bisphosphate-dependent endosome compartmentalization. The Journal of Biological Chemistry. 278: 38786-95. PMID 12878588 DOI: 10.1074/Jbc.M306864200  0.564
2003 Woo LW, Sutcliffe OB, Bubert C, Grasso A, Chander SK, Purohit A, Reed MJ, Potter BV. First dual aromatase-steroid sulfatase inhibitors. Journal of Medicinal Chemistry. 46: 3193-6. PMID 12852749 DOI: 10.1021/Jm034033B  0.34
2003 Ho YT, Purohit A, Vicker N, Newman SP, Robinson JJ, Leese MP, Ganeshapillai D, Woo LW, Potter BV, Reed MJ. Inhibition of carbonic anhydrase II by steroidal and non-steroidal sulphamates. Biochemical and Biophysical Research Communications. 305: 909-14. PMID 12767917 DOI: 10.1016/S0006-291X(03)00865-9  0.39
2003 Raobaikady B, Purohit A, Chander SK, Woo LW, Leese MP, Potter BV, Reed MJ. Inhibition of MCF-7 breast cancer cell proliferation and in vivo steroid sulphatase activity by 2-methoxyoestradiol-bis-sulphamate. The Journal of Steroid Biochemistry and Molecular Biology. 84: 351-8. PMID 12711022 DOI: 10.1016/S0960-0760(03)00049-9  0.358
2003 Fischer DS, Chander SK, Woo LW, Fenton JC, Purohit A, Reed MJ, Potter BV. Novel D-ring modified steroid derivatives as potent, non-estrogenic, steroid sulfatase inhibitors with in vivo activity. The Journal of Steroid Biochemistry and Molecular Biology. 84: 343-9. PMID 12711021 DOI: 10.1016/S0960-0760(03)00048-7  0.402
2003 Fischer DS, Woo LW, Mahon MF, Purohit A, Reed MJ, Potter BV. D-ring modified estrone derivatives as novel potent inhibitors of steroid sulfatase. Bioorganic & Medicinal Chemistry. 11: 1685-700. PMID 12659755 DOI: 10.1016/S0968-0896(03)00042-7  0.357
2003 Vicker N, Ho Y, Robinson J, Woo LL, Purohit A, Reed MJ, Potter BV. Docking studies of sulphamate inhibitors of estrone sulphatase in human carbonic anhydrase II. Bioorganic & Medicinal Chemistry Letters. 13: 863-5. PMID 12617909 DOI: 10.1016/S0960-894X(03)00009-X  0.765
2002 Howarth NM, Purohit A, Robinson JJ, Vicker N, Reed MJ, Potter BV. Estrone 3-sulfate mimics, inhibitors of estrone sulfatase activity: homology model construction and docking studies. Biochemistry. 41: 14801-14. PMID 12475228 DOI: 10.1021/Bi020543G  0.802
2002 Mills SJ, Liu C, Potter BV. Synthesis of D- and L-myo-inositol 2,4,5-trisphosphate and trisphosphorothioate: structural analogues of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research. 337: 1795-801. PMID 12431881 DOI: 10.1016/S0008-6215(02)00289-6  0.587
2002 Riley AM, Morris SA, Nerou EP, Correa V, Potter BV, Taylor CW. Interactions of inositol 1,4,5-trisphosphate (IP(3)) receptors with synthetic poly(ethylene glycol)-linked dimers of IP(3) suggest close spacing of the IP(3)-binding sites. The Journal of Biological Chemistry. 277: 40290-5. PMID 12183463 DOI: 10.1074/jbc.M206925200  0.564
2002 Morris SA, Nerou EP, Riley AM, Potter BV, Taylor CW. Determinants of adenophostin A binding to inositol trisphosphate receptors. The Biochemical Journal. 367: 113-20. PMID 12088506 DOI: 10.1042/Bj20020675  0.605
2002 Guse AH, Cakir-Kiefer C, Fukuoka M, Shuto S, Weber K, Bailey VC, Matsuda A, Mayr GW, Oppenheimer N, Schuber F, Potter BV. Novel hydrolysis-resistant analogues of cyclic ADP-ribose: modification of the "northern" ribose and calcium release activity. Biochemistry. 41: 6744-51. PMID 12022878 DOI: 10.1021/Bi020171B  0.385
2002 Ho MW, Yang X, Carew MA, Zhang T, Hua L, Kwon YU, Chung SK, Adelt S, Vogel G, Riley AM, Potter BV, Shears SB. Regulation of Ins(3,4,5,6)P(4) signaling by a reversible kinase/phosphatase. Current Biology : Cb. 12: 477-82. PMID 11909533 DOI: 10.1016/S0960-9822(02)00713-3  0.623
2002 Shuto S, Horne G, Marwood RD, Potter BV. Total synthesis of nucleobase-modified adenophostin A mimics. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 4937-46. PMID 11763462 DOI: 10.1002/1521-3765(20011119)7:22<4937::Aid-Chem4937>3.0.Co;2-G  0.429
2002 Parekh AB, Riley AM, Potter BV. Adenophostin A and ribophostin, but not inositol 1,4,5-trisphosphate or manno-adenophostin, activate the Ca2+ release-activated Ca2+ current, I(CRAC), in weak intracellular Ca2+ buffer. The Biochemical Journal. 361: 133-41. PMID 11742538 DOI: 10.1042/0264-6021:3610133  0.623
2001 Riley AM, Correa V, Mahon MF, Taylor CW, Potter BV. Bicyclic analogues of D-myo-inositol 1,4,5-trisphosphate related to adenophostin A: synthesis and biological activity. Journal of Medicinal Chemistry. 44: 2108-17. PMID 11405648 DOI: 10.1021/Jm0005499  0.647
2001 Correa V, Riley AM, Shuto S, Horne G, Nerou EP, Marwood RD, Potter BV, Taylor CW. Structural determinants of adenophostin A activity at inositol trisphosphate receptors. Molecular Pharmacology. 59: 1206-15. PMID 11306705 DOI: 10.1124/Mol.59.5.1206  0.64
2001 Ukhanov K, Mills SJ, Potter BV, Walz B. InsP(3)-induced Ca(2+) release in permeabilized invertebrate photoreceptors: a link between phototransduction and Ca(2+) stores. Cell Calcium. 29: 335-45. PMID 11292390 DOI: 10.1054/Ceca.2001.0195  0.603
2001 Horne G, Potter BV. Synthesis of the enantiomers of 6-deoxy-myo-inositol 1,3,4,5-tetrakisphosphate, structural analogues of myo-inositol 1,3,4,5-tetrakisphosphate. Chemistry (Weinheim An Der Bergstrasse, Germany). 7: 80-7. PMID 11205029 DOI: 10.1002/1521-3765(20010105)7:1<80::Aid-Chem80>3.0.Co;2-B  0.416
2001 Purohit A, Woo LW, Barrow D, Hejaz HA, Nicholson RI, Potter BV, Reed MJ. Non-steroidal and steroidal sulfamates: new drugs for cancer therapy. Molecular and Cellular Endocrinology. 171: 129-35. PMID 11165021 DOI: 10.1016/S0303-7207(00)00428-7  0.345
2001 Rosenberg HJ, Riley AM, Correa V, Taylor CW, Potter BV. C-glycoside based mimics of D-myo-inositol 1,4,5-trisphosphate. Carbohydrate Research. 329: 7-16. PMID 11086681 DOI: 10.1016/S0008-6215(00)00175-0  0.605
2000 Malini B, Purohit A, Ganeshapillai D, Woo LW, Potter BV, Reed MJ. Inhibition of steroid sulphatase activity by tricyclic coumarin sulphamates. The Journal of Steroid Biochemistry and Molecular Biology. 75: 253-8. PMID 11282279 DOI: 10.1016/S0960-0760(00)00178-3  0.38
2000 Hermosura MC, Takeuchi H, Fleig A, Riley AM, Potter BV, Hirata M, Penner R. InsP4 facilitates store-operated calcium influx by inhibition of InsP3 5-phosphatase. Nature. 408: 735-40. PMID 11130077 DOI: 10.1038/35047115  0.623
2000 Marwood RD, Jenkins DJ, Correa V, Taylor CW, Potter BV. Contribution of the adenine base to the activity of adenophostin A investigated using a base replacement strategy. Journal of Medicinal Chemistry. 43: 4278-87. PMID 11063623 DOI: 10.1021/Jm000265O  0.336
2000 Woo LL, Purohit A, Malini B, Reed MJ, Potter BV. Potent active site-directed inhibition of steroid sulphatase by tricyclic coumarin-based sulphamates. Chemistry & Biology. 7: 773-91. PMID 11033081 DOI: 10.1016/S1074-5521(00)00023-5  0.792
2000 de Kort M, Correa V, Valentijn AR, van der Marel GA, Potter BV, Taylor CW, van Boom JH. Synthesis of potent agonists of the D-myo-inositol 1,4, 5-trisphosphate receptor based on clustered disaccharide polyphosphate analogues of adenophostin A. Journal of Medicinal Chemistry. 43: 3295-303. PMID 10966748 DOI: 10.1021/Jm000957C  0.391
2000 Purohit A, Hejaz HA, Walden L, MacCarthy-Morrogh L, Packham G, Potter BV, Reed MJ. The effect of 2-methoxyoestrone-3-O-sulphamate on the growth of breast cancer cells and induced mammary tumours. International Journal of Cancer. 85: 584-9. PMID 10699934 DOI: 10.1002/(Sici)1097-0215(20000215)85:4<584::Aid-Ijc22>3.0.Co;2-Q  0.308
2000 Murphy CT, Riley AM, Mills SJ, Lindley CJ, Potter BV, Westwick J. myo-inositol 1,4,6-trisphosphorothioate and myo-inositol 1,3, 6-trisphosphorothioate: partial agonists with very low intrinsic activity at the platelet myo-inositol 1,4,5-trisphosphate receptor. Molecular Pharmacology. 57: 595-601. PMID 10692501 DOI: 10.1124/Mol.57.3.595  0.733
1999 Reyes-Harde M, Potter BV, Galione A, Stanton PK. Induction of hippocampal LTD requires nitric-oxide-stimulated PKG activity and Ca2+ release from cyclic ADP-ribose-sensitive stores. Journal of Neurophysiology. 82: 1569-76. PMID 10482770 DOI: 10.1152/Jn.1999.82.3.1569  0.387
1999 Hejaz HA, Purohit A, Mahon MF, Reed MJ, Potter BV. Synthesis and biological activity of the superestrogen (E)-17-oximino-3-O-sulfamoyl-1,3,5(10)-estratriene: x-ray crystal structure of (E)-17-oximino-3-hydroxy-1,3,5(10)-estratriene. Journal of Medicinal Chemistry. 42: 3188-92. PMID 10447965 DOI: 10.1021/Jm980717L  0.361
1999 Purohit A, Hejaz HA, Woo LW, van Strien AE, Potter BV, Reed MJ. Recent advances in the development of steroid sulphatase inhibitors. The Journal of Steroid Biochemistry and Molecular Biology. 69: 227-38. PMID 10418996 DOI: 10.1016/S0960-0760(99)00039-4  0.395
1999 Migaud ME, Pederick RL, Bailey VC, Potter BV. Probing Aplysia californica adenosine 5'-diphosphate ribosyl cyclase for substrate binding requirements: design of potent inhibitors. Biochemistry. 38: 9105-14. PMID 10413485 DOI: 10.1021/Bi9903392  0.637
1999 Yang X, Rudolf M, Carew MA, Yoshida M, Nerreter V, Riley AM, Chung SK, Bruzik KS, Potter BV, Schultz C, Shears SB. Inositol 1,3,4-trisphosphate acts in vivo as a specific regulator of cellular signaling by inositol 3,4,5,6-tetrakisphosphate. The Journal of Biological Chemistry. 274: 18973-80. PMID 10383396 DOI: 10.1074/Jbc.274.27.18973  0.64
1999 Liu C, Davis RJ, Nahorski SR, Ballereau S, Spiess B, Potter BV. Synthesis, calcium mobilizing, and physicochemical properties of D-chiro-inositol 1,3,4,6-tetrakisphosphate, a novel and potent ligand at the D-myo-inositol 1,4,5-trisphosphate receptor. Journal of Medicinal Chemistry. 42: 1991-8. PMID 10354407 DOI: 10.1021/Jm980733I  0.357
1999 Hirst PH, Riley AM, Mills SJ, Spiers ID, Poyner DR, Freeman S, Potter BV, Smith AW. Inositol polyphosphate-mediated iron transport in Pseudomonas aeruginosa. Journal of Applied Microbiology. 86: 537-43. PMID 10196759 DOI: 10.1046/J.1365-2672.1999.00697.X  0.654
1999 Baraldi E, Djinovic Carugo K, Hyvönen M, Surdo PL, Riley AM, Potter BV, O'Brien R, Ladbury JE, Saraste M. Structure of the PH domain from Bruton's tyrosine kinase in complex with inositol 1,3,4,5-tetrakisphosphate. Structure (London, England : 1993). 7: 449-60. PMID 10196129 DOI: 10.1016/S0969-2126(99)80057-4  0.574
1999 Reyes-Harde M, Empson R, Potter BV, Galione A, Stanton PK. Evidence of a role for cyclic ADP-ribose in long-term synaptic depression in hippocampus. Proceedings of the National Academy of Sciences of the United States of America. 96: 4061-6. PMID 10097163 DOI: 10.1073/Pnas.96.7.4061  0.31
1999 Marwood RD, Riley AM, Correa V, Taylor CW, Potter BV. Simplification of adenophostin A defines a minimal structure for potent glucopyranoside-based mimics of D-myo-inositol 1,4,5-trisphosphate. Bioorganic & Medicinal Chemistry Letters. 9: 453-8. PMID 10091701 DOI: 10.1016/S0960-894X(99)00006-2  0.641
1999 Beecroft MD, Marchant JS, Riley AM, Van Straten NC, Van der Marel GA, Van Boom JH, Potter BV, Taylor CW. Acyclophostin: a ribose-modified analog of adenophostin A with high affinity for inositol 1,4,5-trisphosphate receptors and pH-dependent efficacy. Molecular Pharmacology. 55: 109-17. PMID 9882704 DOI: 10.1124/Mol.55.1.109  0.592
1999 Riley AM, Potter BV. Bicyclic analogues of inositol 1,4,5-trisphosphate based upon adenophostin A Tetrahedron Letters. 40: 2213-2216. DOI: 10.1016/S0040-4039(99)00174-4  0.6
1999 Felemez M, Schlewer G, Jenkins DJ, Correa V, Taylor CW, Potter BV, Spiess B. Inframolecular studies of the protonation of 1d-1,2,4/3,5-cyclopentanepentaol 1,3,4-trisphosphate, a ring-contracted analogue of 1d-myo-inositol 1,4,5-trisphosphate Carbohydrate Research. 322: 95-101. DOI: 10.1016/S0008-6215(99)00193-7  0.372
1999 Felemez M, Marwood RD, Potter BV, Spiess B. Inframolecular Studies of the Protonation of Adenophostin A: Comparison with 1-d-myo-Inositol 1,4,5-Trisphosphate Biochemical and Biophysical Research Communications. 266: 334-340. DOI: 10.1006/Bbrc.1999.1832  0.305
1998 Purohit A, Vernon KA, Hummelinck AE, Woo LW, Hejaz HA, Potter BV, Reed MJ. The development of A-ring modified analogues of oestrone-3-O-sulphamate as potent steroid sulphatase inhibitors with reduced oestrogenicity. The Journal of Steroid Biochemistry and Molecular Biology. 64: 269-75. PMID 9618028 DOI: 10.1016/S0960-0760(97)00196-9  0.404
1998 Purohit A, Potter BV, Parker MG, Reed MJ. Steroid sulphatase: expression, isolation and inhibition for active-site identification studies. Chemico-Biological Interactions. 109: 183-93. PMID 9566745 DOI: 10.1016/S0009-2797(97)00132-4  0.351
1998 Woo LW, Howarth NM, Purohit A, Hejaz HA, Reed MJ, Potter BV. Steroidal and nonsteroidal sulfamates as potent inhibitors of steroid sulfatase. Journal of Medicinal Chemistry. 41: 1068-83. PMID 9544207 DOI: 10.1021/Jm970527V  0.402
1998 Riley AM, Potter BV. l-α-Phosphatidyl-d-myo-inositol 3,5-bisphosphate: total synthesis of a new inositol phospholipid via myo-inositol orthoacetate Tetrahedron Letters. 39: 6769-6772. DOI: 10.1016/S0040-4039(98)01422-1  0.61
1997 Hirata M, Takeuchi H, Riley AM, Mills SJ, Watanabe Y, Potter BV. Inositol 1,4,5-trisphosphate receptor subtypes differentially recognize regioisomers of D-myo-inositol 1,4,5-trisphosphate. The Biochemical Journal. 328: 93-8. PMID 9359838  0.707
1997 Marchant JS, Beecroft MD, Riley AM, Jenkins DJ, Marwood RD, Taylor CW, Potter BV. Disaccharide polyphosphates based upon adenophostin A activate hepatic D-myo-inositol 1,4,5-trisphosphate receptors. Biochemistry. 36: 12780-90. PMID 9335535 DOI: 10.1021/Bi971397V  0.634
1997 Ashamu GA, Sethi JK, Galione A, Potter BV. Roles for adenosine ribose hydroxyl groups in cyclic adenosine 5'-diphosphate ribose-mediated Ca2+ release. Biochemistry. 36: 9509-17. PMID 9235996 DOI: 10.1021/Bi9705671  0.402
1997 Sethi JK, Empson RM, Bailey VC, Potter BV, Galione A. 7-Deaza-8-bromo-cyclic ADP-ribose, the first membrane-permeant, hydrolysis-resistant cyclic ADP-ribose antagonist. The Journal of Biological Chemistry. 272: 16358-63. PMID 9195942 DOI: 10.1074/Jbc.272.26.16358  0.362
1997 DeLisle S, Marksberry EW, Bonnett C, Jenkins DJ, Potter BV, Takahashi M, Tanzawa K. Adenophostin A can stimulate Ca2+ influx without depleting the inositol 1,4,5-trisphosphate-sensitive Ca2+ stores in the Xenopus oocyte. The Journal of Biological Chemistry. 272: 9956-61. PMID 9092535 DOI: 10.1074/Jbc.272.15.9956  0.344
1997 Howarth NM, Purohit A, Reed MJ, Potter BV. Estrone sulfonates as inhibitors of estrone sulfatase. Steroids. 62: 346-50. PMID 9090794 DOI: 10.1016/S0039-128X(96)00243-7  0.413
1997 Bailey VC, Sethi JK, Fortt SM, Galione A, Potter BV. 7-Deaza cyclic adenosine 5'-diphosphate ribose: first example of a Ca(2+)-mobilizing partial agonist related to cyclic adenosine 5'-diphosphate ribose. Chemistry & Biology. 4: 51-61. PMID 9070427 DOI: 10.1016/S1074-5521(97)90236-2  0.341
1997 Woo L, Purohit A, Reed MJ, Potter BV. Oestrone 3-O-(N-acetyl)sulphamate, a potential molecular probe of the active site of oestrone sulphatase Bioorganic & Medicinal Chemistry Letters. 7: 3075-3080. DOI: 10.1016/S0960-894X(97)10167-6  0.333
1996 Mills SJ, Potter BV. Synthesis of D- and L-myo-Inositol 1,4,6-Trisphosphate, Regioisomers of a Ubiquitous Second Messenger. The Journal of Organic Chemistry. 61: 8980-8987. PMID 11667881 DOI: 10.1021/Jo961280X  0.626
1996 Coates PA, Blagbrough IS, Rowan MG, Pearson DP, Lewis T, Potter BV. Preliminary synthetic studies of methyllycaconitine, a potent nicotinic acetylcholine receptor antagonist: rapid syntheses of AE-bicyclic analogues. The Journal of Pharmacy and Pharmacology. 48: 210-3. PMID 8935174 DOI: 10.1111/J.2042-7158.1996.Tb07125.X  0.313
1996 Woo LW, Purohit A, Reed MJ, Potter BV. Active site directed inhibition of estrone sulfatase by nonsteroidal coumarin sulfamates. Journal of Medicinal Chemistry. 39: 1349-51. PMID 8691463 DOI: 10.1021/Jm950931Z  0.304
1996 Woo LW, Lightowler M, Purohit A, Reed MJ, Potter BV. Heteroatom-substituted analogues of the active-site directed inhibitor estra-1,3,5(10)-trien-17-one-3-sulphamate inhibit estrone sulphatase by a different mechanism. The Journal of Steroid Biochemistry and Molecular Biology. 57: 79-88. PMID 8645620 DOI: 10.1016/0960-0760(95)00244-8  0.364
1996 Bailey VC, Fortt SM, Summerhill RJ, Galione A, Potter BV. Cyclic aristeromycin diphosphate ribose: a potent and poorly hydrolysable Ca(2+)-mobilising mimic of cyclic adenosine diphosphate ribose. Febs Letters. 379: 227-30. PMID 8603694 DOI: 10.1016/0014-5793(95)01515-9  0.352
1996 Riley A, Jenkins D, Potter B. Synthesis of Novel Polyphosphate Analogues of Inositol 1,4,5-Trisphosphate Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 73-73. DOI: 10.1080/10426509608054702  0.6
1996 Mills S, Potter B. The Synthesis of Chiral Myo-Inositol Trisphosphate Analogues Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 72-72. DOI: 10.1080/10426509608054701  0.602
1996 Riley A, Mills S, Potter B. Long-Range 31P-31P Spin Coupling Constants in the 31P NMR Spectra of Phosphite Triesters Phosphorus, Sulfur, and Silicon and the Related Elements. 111: 71-71. DOI: 10.1080/10426509608054700  0.675
1995 Van Dijken P, Lammers AA, Ozaki S, Potter BV, Erneux C, Van Haastert PJ. Phosphorylation of inositol 1,4,5-trisphosphate analogues by 3-kinase and dephosphorylation of inositol 1,3,4,5-tetrakisphosphate analogues by 5-phosphatase. European Journal of Biochemistry. 226: 561-6. PMID 8001571 DOI: 10.1111/J.1432-1033.1994.Tb20081.X  0.369
1995 Ward SG, Mills SJ, Liu C, Westwick J, Potter BV. D-myo-inositol 1,4,5-trisphosphate analogues modified at the 3-position inhibit phosphatidylinositol 3-kinase. The Journal of Biological Chemistry. 270: 12075-84. PMID 7744856 DOI: 10.1074/Jbc.270.20.12075  0.631
1995 Reed MJ, Purohit A, Duncan LJ, Singh A, Roberts CJ, Williams GJ, Potter BV. The role of cytokines and sulphatase inhibitors in regulating oestrogen synthesis in breast tumours. The Journal of Steroid Biochemistry and Molecular Biology. 53: 413-20. PMID 7626490 DOI: 10.1016/0960-0760(95)00087-G  0.33
1995 Purohit A, Williams GJ, Roberts CJ, Potter BV, Reed MJ. In vivo inhibition of oestrone sulphatase and dehydroepiandrosterone sulphatase by oestrone-3-O-sulphamate. International Journal of Cancer. 63: 106-11. PMID 7558436 DOI: 10.1002/Ijc.2910630119  0.35
1995 Purohit A, Williams GJ, Howarth NM, Potter BV, Reed MJ. Inactivation of steroid sulfatase by an active site-directed inhibitor, estrone-3-O-sulfamate. Biochemistry. 34: 11508-14. PMID 7547880 DOI: 10.1021/Bi00036A025  0.388
1995 Mills SJ, Riley AM, Murphy CT, Bullock AJ, Westwick J, Potter BV. Myo-inositol 1,4,6-trisphosphorothioate and myo-inositol 1,3,4-trisphosphorothioate: New synthetic Ca2+-mobilising partial agonists at the inositol 1,4,5-trisphosphate receptor Bioorganic and Medicinal Chemistry Letters. 5: 203-208. DOI: 10.1016/0960-894X(95)00012-I  0.732
1994 Hansbro PM, Foster PS, Liu C, Potter BV, Denborough MA. Kinetic analysis of novel inhibitors of inositol polyphosphate metabolism. Biochemical and Biophysical Research Communications. 200: 8-15. PMID 8166746 DOI: 10.1006/Bbrc.1994.1407  0.357
1994 Lampe D, Liu C, Potter BV. Synthesis of selective non-Ca(2+)-mobilizing inhibitors of D-myo-inositol 1,4,5-trisphosphate 5-phosphatase. Journal of Medicinal Chemistry. 37: 907-12. PMID 8151617 DOI: 10.1021/Jm00033A007  0.358
1994 Hodgkin M, Craxton A, Parry JB, Hughes PJ, Potter BV, Michell RH, Kirk CJ. Bovine testis and human erythrocytes contain different subtypes of membrane-associated Ins(1,4,5)P3/Ins(1,3,4,5)P4 5-phosphomonoesterases. The Biochemical Journal. 297: 637-45. PMID 8110204 DOI: 10.1042/Bj2970637  0.347
1994 Safrany ST, Mills SJ, Liu C, Lampe D, Noble NJ, Nahorski SR, Potter BV. Design of potent and selective inhibitors of myo-inositol 1,4,5-trisphosphate 5-phosphatase. Biochemistry. 33: 10763-9. PMID 8075077 DOI: 10.1021/Bi00201A025  0.638
1994 Wilcox RA, Safrany ST, Lampe D, Mills SJ, Nahorski SR, Potter BV. Modification at C2 of myo-inositol 1,4,5-trisphosphate produces inositol trisphosphates and tetrakisphosphates with potent biological activities. European Journal of Biochemistry / Febs. 223: 115-24. PMID 8033885 DOI: 10.1111/J.1432-1033.1994.Tb18972.X  0.638
1994 Foster PS, Hogan SP, Hansbro PM, O'Brien R, Potter BV, Ozaki S, Denborough MA. The metabolism of D-myo-inositol 1,4,5-trisphosphate and D-myo-inositol 1,3,4,5-tetrakisphosphate by porcine skeletal muscle. European Journal of Biochemistry / Febs. 222: 955-64. PMID 8026506 DOI: 10.1111/J.1432-1033.1994.Tb18946.X  0.369
1994 Ward SG, Lampe D, Liu C, Potter BV, Westwick J. Calcium release activity and metabolism of inositol 1,4,5-trisphosphate in T cells. Modulation by novel inositol 1,4,5-trisphosphate 5-phosphatase inhibitors. European Journal of Biochemistry. 222: 515-23. PMID 8020489 DOI: 10.1111/J.1432-1033.1994.Tb18893.X  0.405
1994 Liu C, Al-Hafidh J, Westwick J, Potter BV. Synthesis of 1L-chiro-inositol 2,3,5-trisphosphorothioate, the first partial agonist at the platelet myo-inositol 1,4,5-trisphosphate receptor Bioorganic & Medicinal Chemistry. 2: 253-257. DOI: 10.1016/S0968-0896(00)82168-9  0.352
1993 Wilcox RA, Challiss RA, Baudin G, Vasella A, Potter BV, Nahorski SR. Stereoselectivity of Ins(1,3,4,5)P4 recognition sites: implications for the mechanism of the Ins(1,3,4,5)P4-induced Ca2+ mobilization. The Biochemical Journal. 294: 191-4. PMID 8363572 DOI: 10.1042/Bj2940191  0.381
1993 Wilcox RA, Whitham EM, Liu C, Potter BV, Nahorski SR. Myo-inositol 1,3,4,5-tetrakisphosphate can independently mobilise intracellular calcium, via the inositol 1,4,5-trisphosphate receptor: studies with myo-inositol 1,4,5-trisphosphate-3-phosphorothioate and myo-inositol hexakisphosphate. Febs Letters. 336: 267-71. PMID 8262243 DOI: 10.1016/0014-5793(93)80817-E  0.373
1993 Mills SJ, Safrany ST, Wilcox RA, Nahorski SR, Potter BV. Synthesis of myo-inositol 1,2,4,5-tetrakisphosphate, a Ca2+-mobilising tetrakisphosphate with a potency similar to myo-inositol 1,4,5-trisphosphate Bioorganic and Medicinal Chemistry Letters. 3: 1505-1510. DOI: 10.1016/S0960-894X(00)80007-4  0.622
1992 Wilcox RA, Nahorski SR, Sawyer DA, Liu C, Potter BV. The role of the 2- and 3-hydroxyl groups of 1D-myo-inositol 1,4,5-trisphosphate in the mobilisation of calcium from permeabilised human 1321N1 astrocytoma cells. Carbohydrate Research. 234: 237-46. PMID 1334801 DOI: 10.1016/0008-6215(92)85051-Z  0.378
1992 Safrany ST, Sawyer DA, Nahorski SR, Potter BV. Synthetic D- and L-enantiomers of 2,2-difluoro-2-deoxy-myo-inositol 1,4,5-trisphosphate interact differently with myo-inositol 1,4,5-trisphosphate binding proteins: identification of a potent small molecule 3-kinase inhibitor. Chirality. 4: 415-22. PMID 1334423 DOI: 10.1002/Chir.530040703  0.389
1992 Safrany ST, Wilcox RA, Liu C, Potter BV, Nahorski SR. 3-position modification of myo-inositol 1,4,5-trisphosphate: consequences for intracellular Ca2+ mobilisation and enzyme recognition. European Journal of Pharmacology. 226: 265-72. PMID 1330634 DOI: 10.1016/0922-4106(92)90071-3  0.376
1992 Potter BV, Nahorski SR. Synthesis and biology of inositol polyphosphate analogues. Biochemical Society Transactions. 20: 434-42. PMID 1327920 DOI: 10.1042/Bst0200434  0.304
1992 Liu C, Safrany ST, Nahorski SR, Potter BV. Synthesis of L-chiro-inositol 1,4,6-trisphosphorothioate, a potent and selective inhibitor of myo-inositol 1,4,5-trisphosphate 5-phosphatase Bioorganic & Medicinal Chemistry Letters. 2: 1523-1528. DOI: 10.1016/S0960-894X(00)80421-7  0.319
1991 Challiss RA, Willcocks AL, Mulloy B, Potter BV, Nahorski SR. Characterization of inositol 1,4,5-trisphosphate- and inositol 1,3,4,5-tetrakisphosphate-binding sites in rat cerebellum. The Biochemical Journal. 274: 861-7. PMID 2012613 DOI: 10.1042/Bj2740861  0.345
1991 Petersen CC, Toescu EC, Potter BV, Petersen OH. Inositol triphosphate produces different patterns of cytoplasmic Ca2+ spiking depending on its concentration. Febs Letters. 293: 179-82. PMID 1959657 DOI: 10.1016/0014-5793(91)81181-7  0.305
1991 Gawler DJ, Potter BV, Gigg R, Nahorski SR. Interactions between inositol tris- and tetrakis-phosphates. Effects on intracellular Ca2+ mobilization in SH-SY5Y cells. The Biochemical Journal. 276: 163-7. PMID 1645528 DOI: 10.1042/Bj2760163  0.375
1991 Sawyer DA, Potter BV. Total synthesis of L-2,2-difluoro-2-deoxy-MYO-inositol 1,4,5-trisphosphate, a potent inhibitor of the enzymes of d-MYO-inositol 1,4,5-trisphosphate metabolism Bioorganic & Medicinal Chemistry Letters. 1: 705-710. DOI: 10.1016/S0960-894X(01)81052-0  0.35
1990 Gawler DJ, Potter BV, Nahorski SR. Inositol 1,3,4,5-tetrakisphosphate-induced release of intracellular Ca2+ in SH-SY5Y neuroblastoma cells. The Biochemical Journal. 272: 519-24. PMID 2176465 DOI: 10.1042/Bj2720519  0.378
1990 Safrany ST, Sawyer D, Wojcikiewicz RJ, Nahorski SR, Potter BV. Ca2(+)-mobilising properties of synthetic fluoro-analogues of myo-inositol 1,4,5-trisphosphate and their interaction with myo-inositol 1,4,5-trisphosphate 3-kinase and 5-phosphatase. Febs Letters. 276: 91-4. PMID 2176165 DOI: 10.1016/0014-5793(90)80515-K  0.4
1990 Chilvers ER, Challiss RA, Willcocks AL, Potter BV, Barnes PJ, Nahorski SR. Characterisation of stereospecific binding sites for inositol 1,4,5-trisphosphate in airway smooth muscle. British Journal of Pharmacology. 99: 297-302. PMID 2158373 DOI: 10.1111/J.1476-5381.1990.Tb14698.X  0.34
1990 Nunn DL, Potter BV, Taylor CW. Molecular target sizes of inositol 1,4,5-trisphosphate receptors in liver and cerebellum. The Biochemical Journal. 265: 393-8. PMID 2154187 DOI: 10.1042/Bj2650393  0.38
1990 Berridge MJ, Potter BV. Inositol trisphosphate analogues induce different oscillatory patterns in Xenopus oocytes. Cell Regulation. 1: 675-81. PMID 1706629 DOI: 10.1091/Mbc.1.9.675  0.305
1989 Changya L, Gallacher DV, Irvine RF, Potter BV, Petersen OH. Inositol 1,3,4,5-tetrakisphosphate is essential for sustained activation of the Ca2+-dependent K+ current in single internally perfused mouse lacrimal acinar cells. The Journal of Membrane Biology. 109: 85-93. PMID 2788744 DOI: 10.1007/Bf01870793  0.355
1989 Taylor CW, Berridge MJ, Cooke AM, Potter BV. Inositol 1,4,5-trisphosphorothioate, a stable analogue of inositol trisphosphate which mobilizes intracellular calcium. The Biochemical Journal. 259: 645-50. PMID 2786414 DOI: 10.1042/Bj2590645  0.39
1989 Nahorski SR, Potter BV. Molecular recognition of inositol polyphosphates by intracellular receptors and metabolic enzymes. Trends in Pharmacological Sciences. 10: 139-44. PMID 2546303 DOI: 10.1016/0165-6147(89)90165-X  0.351
1989 Thévenod F, Dehlinger-Kremer M, Kemmer TP, Christian AL, Potter BV, Schulz I. Characterization of inositol 1,4,5-trisphosphate-sensitive (IsCaP) and -insensitive (IisCaP) nonmitochondrial Ca2+ pools in rat pancreatic acinar cells. The Journal of Membrane Biology. 109: 173-86. PMID 2527996 DOI: 10.1007/Bf01870856  0.306
1989 McCarren M, Potter BV, Miller RJ. A metabolically stable analog of 1,4,5-inositol trisphosphate activates a novel K+ conductance in pyramidal cells of the rat hippocampal slice. Neuron. 3: 461-71. PMID 2518371 DOI: 10.1016/0896-6273(89)90205-5  0.305
1989 Wakui M, Potter BV, Petersen OH. Pulsatile intracellular calcium release does not depend on fluctuations in inositol trisphosphate concentration. Nature. 339: 317-20. PMID 2498663 DOI: 10.1038/339317A0  0.309
1988 Taylor CW, Berridge MJ, Brown KD, Cooke AM, Potter BV. DL-myo-inositol 1,4,5-trisphosphorothioate mobilizes intracellular calcium in Swiss 3T3 cells and Xenopus oocytes. Biochemical and Biophysical Research Communications. 150: 626-32. PMID 3342041 DOI: 10.1016/0006-291X(88)90438-X  0.327
1988 Willcocks AL, Potter BV, Cooke AM, Nahorski SR. Myo-inositol(1,4,5)trisphosphorothioate binds to specific [3H]inositol(1,4,5)trisphosphate sites in rat cerebellum and is resistant to 5-phosphatase. European Journal of Pharmacology. 155: 181-3. PMID 2854071 DOI: 10.1016/0014-2999(88)90420-7  0.345
1987 Hamblin MR, Flora JS, Potter BV. myo-Inositol phosphorothioates, phosphatase-resistant analogues of myo-inositol phosphates. Synthesis of DL-myo-inositol 1,4-bisphosphate and DL-myo-inositol 1,4-bisphosphorothioate. The Biochemical Journal. 246: 771-4. PMID 3689330 DOI: 10.1042/Bj2460771  0.325
1987 Willcocks AL, Cooke AM, Potter BV, Nahorski SR. Stereospecific recognition sites for [3H]inositol(1,4,5)-triphosphate in particulate preparations of rat cerebellum. Biochemical and Biophysical Research Communications. 146: 1071-8. PMID 3039991 DOI: 10.1016/0006-291X(87)90756-X  0.378
1984 Potter BV, Eckstein F. Cleavage of phosphorothioate-substituted DNA by restriction endonucleases. The Journal of Biological Chemistry. 259: 14243-8. PMID 6094546  0.347
1983 Potter BV, Eckstein F, Uznański B. A stereospecifically 18O-labelled deoxydinucleoside phosphate block for incorporation into an oligonucleotide. Nucleic Acids Research. 11: 7087-103. PMID 6634410 DOI: 10.1093/Nar/11.20.7087  0.407
1983 Potter BV, Romaniuk PJ, Eckstein F. Stereochemical course of DNA hydrolysis by nuclease S1 Journal of Biological Chemistry. 258: 1758-1760. PMID 6296110  0.409
1982 Pollard-Knight D, Potter BV, Cullis PM, Lowe G, Cornish-Bowden A. The stereochemical course of phosphoryl transfer catalysed by glucokinase. The Biochemical Journal. 201: 421-3. PMID 6896275 DOI: 10.1042/Bj2010421  0.488
1982 Lowe G, Potter BV. The stereochemical course of phosphoryl transfer catalysed by glucose 6-phosphatase. The Biochemical Journal. 201: 665-8. PMID 6284126 DOI: 10.1042/Bj2010665  0.485
1981 Lowe G, Potter BV. The stereochemical course of yeast hexokinase-catalysed phosphoryl transfer by using adenosine 5'[gamma(S)-16O,17O,18O]triphosphate as substrate. The Biochemical Journal. 199: 227-33. PMID 7039616 DOI: 10.1042/Bj1990227  0.49
1981 Lowe G, Potter BV. A stereochemical investigation of phosphoryl transfer catalysed by phosphoglucomutase by the use of alpha-D-glucose 1-[(S)-16O,17O,18O]phosphate. The Biochemical Journal. 199: 693-8. PMID 6462135 DOI: 10.1042/Bj1990693  0.488
1981 Jarvest RL, Lowe G, Potter BV. The stereochemical course of phosphoryl transfer catalysed by Bacillus stearothermophilus and rabbit skeletal-muscle phosphofructokinase with a chiral [16O,17O,18O]phosphate ester. The Biochemical Journal. 199: 427-32. PMID 6462132 DOI: 10.1042/Bj1990427  0.47
1981 Lowe G, Cullis PM, Jarvest RL, Potter BV, Sproat BS. Stereochemistry of phosphoryl transfer. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 293: 75-92. PMID 6115426 DOI: 10.1098/Rstb.1981.0062  0.492
1980 Jones VT, Lowe G, Potter BV. Evidence against a step-wise mechanism for the fumarase-catalysed dehydration of (2S)-malate. European Journal of Biochemistry. 108: 433-7. PMID 7408860 DOI: 10.1111/J.1432-1033.1980.Tb04739.X  0.464
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