K Ravi Acharya - Publications

Bath University 

119 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Grozdanovic MM, Doyle CB, Liu L, Maybruck B, Kwatia MA, Thiyagarajan N, Acharya KR, Ackerman SJ. Charcot-Leyden Crystal Protein/Galectin-10 Interacts with Cationic Ribonucleases and is Required for Eosinophil Granulogenesis. The Journal of Allergy and Clinical Immunology. PMID 31982451 DOI: 10.1016/J.Jaci.2020.01.013  0.6
2017 Bradshaw WJ, Rehman S, Pham TT, Thiyagarajan N, Lee RL, Subramanian V, Acharya KR. Structural insights into human angiogenin variants implicated in Parkinson's disease and Amyotrophic Lateral Sclerosis. Scientific Reports. 7: 41996. PMID 28176817 DOI: 10.1038/Srep41996  0.6
2016 Larmuth KM, Masuyer G, Douglas RG, Schwager SL, Acharya KR, Sturrock ED. Kinetic and structural characterization of amyloid-β peptide hydrolysis by human angiotensin-1-converting enzyme. The Febs Journal. 283: 1060-76. PMID 26748546 DOI: 10.1111/Febs.13647  1
2016 Liang S, Acharya KR. Structural basis of substrate specificity in porcine RNase 4. The Febs Journal. PMID 26748441 DOI: 10.1111/Febs.13646  1
2016 Schmidt A, Hammerbacher AS, Bastian M, Nieken KJ, Klockgether J, Merighi M, Lapouge K, Poschgan C, Kölle J, Acharya KR, Ulrich M, Tümmler B, Unden G, Kaever V, Lory S, et al. Oxygen-dependent regulation of c-di-GMP synthesis by SadC controls alginate production in Pseudomonas aeruginosa. Environmental Microbiology. PMID 26743546 DOI: 10.1111/1462-2920.13208  0.01
2015 Harrison C, Acharya KR. A new high-resolution crystal structure of the Drosophila melanogaster angiotensin converting enzyme homologue, AnCE. Febs Open Bio. 5: 661-7. PMID 26380810 DOI: 10.1016/J.Fob.2015.08.004  1
2015 Masuyer G, Davies JR, Moore K, Chaddock JA, Ravi Acharya K. Structural analysis of Clostridium botulinum neurotoxin type D as a platform for the development of targeted secretion inhibitors. Scientific Reports. 5: 13397. PMID 26324071 DOI: 10.1038/Srep13397  1
2015 Iyer S, La-Borde PJ, Payne KA, Parsons MR, Turner AJ, Isaac RE, Acharya KR. Crystal structure of X-prolyl aminopeptidase from Caenorhabditis elegans: A cytosolic enzyme with a di-nuclear active site. Febs Open Bio. 5: 292-302. PMID 25905034 DOI: 10.1016/J.Fob.2015.03.013  1
2015 Bradshaw WJ, Davies AH, Chambers CJ, Roberts AK, Shone CC, Acharya KR. Molecular features of the sortase enzyme family. The Febs Journal. 282: 2097-114. PMID 25845800 DOI: 10.1111/Febs.13288  1
2015 Chambers CJ, Roberts AK, Shone CC, Acharya KR. Structure and function of a Clostridium difficile sortase enzyme. Scientific Reports. 5: 9449. PMID 25801974 DOI: 10.1038/Srep09449  1
2015 Ramaswamy S, Sleiman MH, Masuyer G, Arbez-Gindre C, Micha-Screttas M, Calogeropoulou T, Steele BR, Acharya KR. Structural basis of multivalent galactose-based dendrimer recognition by human galectin-7. The Febs Journal. 282: 372-87. PMID 25367374 DOI: 10.1111/Febs.13140  1
2014 Masuyer G, Yates CJ, Sturrock ED, Acharya KR. Angiotensin-I converting enzyme (ACE): structure, biological roles, and molecular basis for chloride ion dependence. Biological Chemistry. 395: 1135-49. PMID 25205727 DOI: 10.1515/Hsz-2014-0157  1
2014 Harrison C, Acharya KR. ACE for all - a molecular perspective. Journal of Cell Communication and Signaling. 8: 195-210. PMID 25027949 DOI: 10.1007/S12079-014-0236-8  1
2014 Kramer GJ, Mohd A, Schwager SL, Masuyer G, Acharya KR, Sturrock ED, Bachmann BO. Interkingdom pharmacology of Angiotensin-I converting enzyme inhibitor phosphonates produced by actinomycetes. Acs Medicinal Chemistry Letters. 5: 346-51. PMID 24900839 DOI: 10.1021/Ml4004588  1
2014 Acharya KR, Ackerman SJ. Eosinophil granule proteins: form and function. The Journal of Biological Chemistry. 289: 17406-15. PMID 24802755 DOI: 10.1074/Jbc.R113.546218  1
2014 Yates CJ, Masuyer G, Schwager SL, Akif M, Sturrock ED, Acharya KR. Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE). The Journal of Biological Chemistry. 289: 1798-814. PMID 24297181 DOI: 10.1074/Jbc.M113.512335  1
2014 Masuyer G, Akif M, Czarny B, Beau F, Schwager SL, Sturrock ED, Isaac RE, Dive V, Acharya KR. Crystal structures of highly specific phosphinic tripeptide enantiomers in complex with the angiotensin-I converting enzyme. The Febs Journal. 281: 943-56. PMID 24289879 DOI: 10.1111/Febs.12660  1
2014 Michaud A, Acharya KR, Masuyer G, Quenech'du N, Gribouval O, Morinière V, Gubler MC, Corvol P. Absence of cell surface expression of human ACE leads to perinatal death. Human Molecular Genetics. 23: 1479-91. PMID 24163131 DOI: 10.1093/Hmg/Ddt535  1
2014 Douglas RG, Sharma RK, Masuyer G, Lubbe L, Zamora I, Acharya KR, Chibale K, Sturrock ED. Fragment-based design for the development of N-domain-selective angiotensin-1-converting enzyme inhibitors. Clinical Science (London, England : 1979). 126: 305-13. PMID 24015848 DOI: 10.1042/Cs20130403  1
2013 Thiyagarajan N, Acharya KR. Crystal structure of human angiogenin with an engineered loop exhibits conformational flexibility at the functional regions of the molecule. Febs Open Bio. 3: 65-70. PMID 23772376 DOI: 10.1016/J.Fob.2012.12.003  1
2013 Iyer S, Holloway DE, Acharya KR. Crystal structures of murine angiogenin-2 and -3-probing 'structure--function' relationships amongst angiogenin homologues. The Febs Journal. 280: 302-18. PMID 23170778 DOI: 10.1111/Febs.12071  1
2012 Walker NJ, Clark EA, Ford DC, Bullifent HL, McAlister EV, Duffield ML, Acharya KR, Oyston PC. Structure and function of cytidine monophosphate kinase from Yersinia pseudotuberculosis, essential for virulence but not for survival. Open Biology. 2: 120142. PMID 23271832 DOI: 10.1098/Rsob.120142  1
2012 Thiyagarajan N, Pham TT, Stinson B, Sundriyal A, Tumbale P, Lizotte-Waniewski M, Brew K, Acharya KR. Structure of a metal-independent bacterial glycosyltransferase that catalyzes the synthesis of histo-blood group A antigen. Scientific Reports. 2: 940. PMID 23230506 DOI: 10.1038/Srep00940  1
2012 Akif M, Masuyer G, Bingham RJ, Sturrock ED, Isaac RE, Acharya KR. Structural basis of peptide recognition by the angiotensin-1 converting enzyme homologue AnCE from Drosophila melanogaster. The Febs Journal. 279: 4525-34. PMID 23082758 DOI: 10.1111/Febs.12038  1
2012 Masuyer G, Schwager SL, Sturrock ED, Isaac RE, Acharya KR. Molecular recognition and regulation of human angiotensin-I converting enzyme (ACE) activity by natural inhibitory peptides. Scientific Reports. 2: 717. PMID 23056909 DOI: 10.1038/Srep00717  1
2012 Stancombe PR, Masuyer G, Birch-Machin I, Beard M, Foster KA, Chaddock JA, Acharya KR. Engineering botulinum neurotoxin domains for activation by toxin light chain. The Febs Journal. 279: 515-23. PMID 22141396 DOI: 10.1111/J.1742-4658.2011.08444.X  1
2012 Masuyer G, Jabeen T, Öberg CT, Leffler H, Nilsson UJ, Acharya KR. Inhibition mechanism of human galectin-7 by a novel galactose-benzylphosphate inhibitor. The Febs Journal. 279: 193-202. PMID 22059385 DOI: 10.1111/J.1742-4658.2011.08414.X  1
2011 Masuyer G, Stancombe P, Chaddock JA, Acharya KR. Structures of engineered Clostridium botulinum neurotoxin derivatives. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 1466-72. PMID 22139146 DOI: 10.1107/S1744309111034671  1
2011 Acharya KR. Special issue: engineering toxins for 21st-century therapies: introduction. The Febs Journal. 278: 4453. PMID 21973050 DOI: 10.1111/J.1742-4658.2011.08384.X  1
2011 Iyer S, Acharya KR. Tying the knot: the cystine signature and molecular-recognition processes of the vascular endothelial growth factor family of angiogenic cytokines. The Febs Journal. 278: 4304-22. PMID 21917115 DOI: 10.1111/J.1742-4658.2011.08350.X  1
2011 Holloway DE, Singh UP, Shogen K, Acharya KR. Crystal structure of Onconase at 1.1 Å resolution--insights into substrate binding and collective motion. The Febs Journal. 278: 4136-49. PMID 21895975 DOI: 10.1111/J.1742-4658.2011.08320.X  1
2011 Akif M, Masuyer G, Schwager SL, Bhuyan BJ, Mugesh G, Isaac RE, Sturrock ED, Acharya KR. Structural characterization of angiotensin I-converting enzyme in complex with a selenium analogue of captopril. The Febs Journal. 278: 3644-50. PMID 21810173 DOI: 10.1111/J.1742-4658.2011.08276.X  1
2011 Davies AH, Roberts AK, Shone CC, Acharya KR. Super toxins from a super bug: structure and function of Clostridium difficile toxins. The Biochemical Journal. 436: 517-26. PMID 21615333 DOI: 10.1042/Bj20110106  1
2011 Holbourn KP, Malfois M, Acharya KR. First structural glimpse of CCN3 and CCN5 multifunctional signaling regulators elucidated by small angle x-ray scattering. The Journal of Biological Chemistry. 286: 22243-9. PMID 21543320 DOI: 10.1074/Jbc.M111.225755  1
2011 Clark EA, Walker N, Ford DC, Cooper IA, Oyston PC, Acharya KR. Molecular recognition of chymotrypsin by the serine protease inhibitor ecotin from Yersinia pestis. The Journal of Biological Chemistry. 286: 24015-22. PMID 21531711 DOI: 10.1074/Jbc.M111.225730  1
2011 Holbourn KP, Lloyd MD, Thompson AS, Threadgill MD, Acharya KR. Cloning, purification, crystallization and preliminary crystallographic analysis of the human histone deacetylase sirtuin 1 Acta Crystallographica Section F: Structural Biology and Crystallization Communications. 67: 461-463. PMID 21505241 DOI: 10.1107/S1744309111003277  1
2011 Holbourn KP, Acharya KR. Cloning, expression and purification of the CCN family of proteins in Escherichia coli. Biochemical and Biophysical Research Communications. 407: 837-41. PMID 21458411 DOI: 10.1016/J.Bbrc.2011.03.122  1
2011 Chaddock JA, Acharya KR. Engineering toxins for 21st century therapies. The Febs Journal. 278: 899-904. PMID 21382174 DOI: 10.1111/J.1742-4658.2011.08013.X  1
2011 Akif M, Schwager SL, Anthony CS, Czarny B, Beau F, Dive V, Sturrock ED, Acharya KR. Novel mechanism of inhibition of human angiotensin-I-converting enzyme (ACE) by a highly specific phosphinic tripeptide. The Biochemical Journal. 436: 53-9. PMID 21352096 DOI: 10.1042/Bj20102123  1
2011 Thiyagarajan N, Smith BD, Raines RT, Acharya KR. Functional and structural analyses of N-acylsulfonamide-linked dinucleoside inhibitors of RNase A. The Febs Journal. 278: 541-9. PMID 21205197 DOI: 10.1111/J.1742-4658.2010.07976.X  1
2011 Masuyer G, Beard M, Cadd VA, Chaddock JA, Acharya KR. Structure and activity of a functional derivative of Clostridium botulinum neurotoxin B. Journal of Structural Biology. 174: 52-7. PMID 21078393 DOI: 10.1016/J.Jsb.2010.11.010  1
2010 Brew K, Tumbale P, Acharya KR. Family 6 glycosyltransferases in vertebrates and bacteria: inactivation and horizontal gene transfer may enhance mutualism between vertebrates and bacteria. The Journal of Biological Chemistry. 285: 37121-7. PMID 20870714 DOI: 10.1074/Jbc.R110.176248  1
2010 Anthony CS, Corradi HR, Schwager SLU, Redelinghuys P, Georgiadis D, Dive V, Acharya KR, Sturrock ED. The N domain of human angiotensin-I-converting enzyme: The role of N-glycosylation and the crystal structure in complex with an N domain-specific phosphinic inhibitor, RXP407 Journal of Biological Chemistry. 285: 35685-35693. PMID 20826823 DOI: 10.1074/Jbc.M110.167866  1
2010 Akif M, Ntai I, Sturrock ED, Isaac RE, Bachmann BO, Acharya KR. Crystal structure of a phosphonotripeptide K-26 in complex with angiotensin converting enzyme homologue (AnCE) from Drosophila melanogaster. Biochemical and Biophysical Research Communications. 398: 532-6. PMID 20599761 DOI: 10.1016/J.Bbrc.2010.06.113  1
2010 Iyer S, Darley PI, Acharya KR. Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1(D2): recognition and specificity. The Journal of Biological Chemistry. 285: 23779-89. PMID 20501651 DOI: 10.1074/Jbc.M110.130658  1
2010 Akif M, Georgiadis D, Mahajan A, Dive V, Sturrock ED, Isaac RE, Acharya KR. High-resolution crystal structures of Drosophila melanogaster angiotensin-converting enzyme in complex with novel inhibitors and antihypertensive drugs. Journal of Molecular Biology. 400: 502-17. PMID 20488190 DOI: 10.1016/J.Jmb.2010.05.024  1
2010 Sundriyal A, Roberts AK, Ling R, McGlashan J, Shone CC, Acharya KR. Expression, purification and cell cytotoxicity of actin-modifying binary toxin from Clostridium difficile. Protein Expression and Purification. 74: 42-8. PMID 20433927 DOI: 10.1016/J.Pep.2010.04.014  1
2010 Leese MP, Jourdan F, Kimberley MR, Cozier GE, Thiyagarajan N, Stengel C, Regis-Lydi S, Foster PA, Newman SP, Acharya KR, Ferrandis E, Purohit A, Reed MJ, Potter BV. Chimeric microtubule disruptors. Chemical Communications (Cambridge, England). 46: 2907-9. PMID 20386818 DOI: 10.1039/C002558E  1
2010 Cozier GE, Leese MP, Lloyd MD, Baker MD, Thiyagarajan N, Acharya KR, Potter BV. Structures of human carbonic anhydrase II/inhibitor complexes reveal a second binding site for steroidal and nonsteroidal inhibitors. Biochemistry. 49: 3464-76. PMID 20297840 DOI: 10.1021/Bi902178W  1
2009 Kirby JM, Ahern H, Roberts AK, Kumar V, Freeman Z, Acharya KR, Shone CC. Cwp84, a surface-associated cysteine protease, plays a role in the maturation of the surface layer of Clostridium difficile. The Journal of Biological Chemistry. 284: 34666-73. PMID 19808679 DOI: 10.1074/Jbc.M109.051177  1
2009 Jamaluddin H, Tumbale P, Ferns TA, Thiyagarajan N, Brew K, Acharya KR. Crystal structure of alpha-1,3-galactosyltransferase (alpha3GT) in a complex with p-nitrophenyl-beta-galactoside (pNPbetaGal). Biochemical and Biophysical Research Communications. 385: 601-4. PMID 19486884 DOI: 10.1016/J.Bbrc.2009.05.111  1
2009 Masuyer G, Thiyagarajan N, James PL, Marks PM, Chaddock JA, Acharya KR. Crystal structure of a catalytically active, non-toxic endopeptidase derivative of Clostridium botulinum toxin A. Biochemical and Biophysical Research Communications. 381: 50-3. PMID 19351593 DOI: 10.1016/J.Bbrc.2009.02.003  1
2009 Holloway DE, Chavali GB, Leonidas DD, Baker MD, Acharya KR. Influence of naturally-occurring 5'-pyrophosphate-linked substituents on the binding of adenylic inhibitors to ribonuclease a: an X-ray crystallographic study. Biopolymers. 91: 995-1008. PMID 19191310 DOI: 10.1002/Bip.21158  1
2008 Leonard P, Scotney PD, Jabeen T, Iyer S, Fabri LJ, Nash AD, Acharya KR. Crystal structure of vascular endothelial growth factor-B in complex with a neutralising antibody Fab fragment. Journal of Molecular Biology. 384: 1203-17. PMID 18930733 DOI: 10.1016/J.Jmb.2008.09.076  1
2008 Holbourn KP, Acharya KR, Perbal B. The CCN family of proteins: structure-function relationships. Trends in Biochemical Sciences. 33: 461-73. PMID 18789696 DOI: 10.1016/J.Tibs.2008.07.006  1
2008 Tumbale P, Jamaluddin H, Thiyagarajan N, Acharya KR, Brew K. Screening a limited structure-based library identifies UDP-GalNAc-specific mutants of alpha-1,3-galactosyltransferase. Glycobiology. 18: 1036-43. PMID 18782853 DOI: 10.1093/Glycob/Cwn083  1
2008 Ulrich M, Petre A, Youhnovski N, Prömm F, Schirle M, Schumm M, Pero RS, Doyle A, Checkel J, Kita H, Thiyagarajan N, Acharya KR, Schmid-Grendelmeier P, Simon HU, Schwarz H, et al. Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase. The Journal of Biological Chemistry. 283: 28629-40. PMID 18694936 DOI: 10.1074/Jbc.M801196200  0.6
2008 Tumbale P, Jamaluddin H, Thiyagarajan N, Brew K, Acharya KR. Structural basis of UDP-galactose binding by alpha-1,3-galactosyltransferase (alpha3GT): role of negative charge on aspartic acid 316 in structure and activity. Biochemistry. 47: 8711-8. PMID 18651752 DOI: 10.1021/Bi800852A  1
2008 Jabeen T, Leonard P, Jamaluddin H, Acharya KR. Structure of mouse IP-10, a chemokine. Acta Crystallographica. Section D, Biological Crystallography. 64: 611-9. PMID 18560148 DOI: 10.1107/S0907444908007026  1
2008 Kazakou K, Holloway DE, Prior SH, Subramanian V, Acharya KR. Ribonuclease A homologues of the zebrafish: polymorphism, crystal structures of two representatives and their evolutionary implications. Journal of Molecular Biology. 380: 206-22. PMID 18508078 DOI: 10.1016/J.Jmb.2008.04.070  1
2008 Subramanian V, Crabtree B, Acharya KR. Human angiogenin is a neuroprotective factor and amyotrophic lateral sclerosis associated angiogenin variants affect neurite extension/pathfinding and survival of motor neurons. Human Molecular Genetics. 17: 130-49. PMID 17916583 DOI: 10.1093/Hmg/Ddm290  1
2008 Jamaluddin H, Tumbale P, Withers SG, Acharya KR, Brew K. Corrigendum to "Conformational Changes Induced by Binding of UDP-2F-galactose to α-1,3 Galactosyltransferase-Implications for Catalysis" [J. Mol. Biol. 369 (2007) 1270-1281] (DOI:10.1016/j.jmb.2007.04.012) Journal of Molecular Biology. 378: 295-296. DOI: 10.1016/J.Jmb.2008.02.030  1
2007 Crabtree B, Thiyagarajan N, Prior SH, Wilson P, Iyer S, Ferns T, Shapiro R, Brew K, Subramanian V, Acharya KR. Characterization of human angiogenin variants implicated in amyotrophic lateral sclerosis. Biochemistry. 46: 11810-8. PMID 17900154 DOI: 10.1021/Bi701333H  1
2007 Hamze AB, Wei S, Bahudhanapati H, Kota S, Acharya KR, Brew K. Constraining specificity in the N-domain of tissue inhibitor of metalloproteinases-1; gelatinase-selective inhibitors. Protein Science : a Publication of the Protein Society. 16: 1905-13. PMID 17660250 DOI: 10.1110/Ps.072978507  1
2007 Jamaluddin H, Tumbale P, Withers SG, Acharya KR, Brew K. Conformational Changes Induced by Binding UDP-2F-galactose to α-1,3 Galactosyltransferase- Implications for Catalysis Journal of Molecular Biology. 369: 1270-1281. PMID 17493636 DOI: 10.1016/J.Jmb.2007.04.012  1
2007 Corradi HR, Chitapi I, Sewell BT, Georgiadis D, Dive V, Sturrock ED, Acharya KR. The structure of testis angiotensin-converting enzyme in complex with the C domain-specific inhibitor RXPA380. Biochemistry. 46: 5473-8. PMID 17439247 DOI: 10.1021/Bi700275E  1
2007 Crabtree B, Holloway DE, Baker MD, Acharya KR, Subramanian V. Biological and structural features of murine angiogenin-4, an angiogenic protein. Biochemistry. 46: 2431-43. PMID 17279775 DOI: 10.1021/Bi062158N  1
2007 Rummel A, Eichner T, Weil T, Karnath T, Gutcaits A, Mahrhold S, Sandhoff K, Proia RL, Acharya KR, Bigalke H, Binz T. Identification of the protein receptor binding site of botulinum neurotoxins B and G proves the double-receptor concept. Proceedings of the National Academy of Sciences of the United States of America. 104: 359-64. PMID 17185412 DOI: 10.1073/Pnas.0609713104  1
2006 Corradi HR, Corrigall AV, Boix E, Mohan CG, Sturrock ED, Meissner PN, Acharya KR. Crystal structure of protoporphyrinogen oxidase from Myxococcus xanthus and its complex with the inhibitor acifluorfen. The Journal of Biological Chemistry. 281: 38625-33. PMID 17046834 DOI: 10.1074/Jbc.M606640200  1
2006 Mandron M, Ariès MF, Brehm RD, Tranter HS, Acharya KR, Charveron M, Davrinche C. Human dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarization. The Journal of Allergy and Clinical Immunology. 117: 1141-7. PMID 16675344 DOI: 10.1016/J.Jaci.2005.12.1360  1
2006 Greenway MJ, Andersen PM, Russ C, Ennis S, Cashman S, Donaghy C, Patterson V, Swingler R, Kieran D, Prehn J, Morrison KE, Green A, Acharya KR, Brown RH, Hardiman O. ANG mutations segregate with familial and 'sporadic' amyotrophic lateral sclerosis. Nature Genetics. 38: 411-3. PMID 16501576 DOI: 10.1038/Ng1742  1
2006 Corradi HR, Schwager SL, Nchinda AT, Sturrock ED, Acharya KR. Crystal structure of the N domain of human somatic angiotensin I-converting enzyme provides a structural basis for domain-specific inhibitor design. Journal of Molecular Biology. 357: 964-74. PMID 16476442 DOI: 10.1016/J.Jmb.2006.01.048  1
2006 Baker MD, Holloway DE, Swaminathan GJ, Acharya KR. Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5'-ATP, Ap3A, Ap4A, and Ap5A. Biochemistry. 45: 416-26. PMID 16401072 DOI: 10.1021/Bi0518592  1
2006 Baker MD, Holloway DE, Swaminathan GJ, Acharya KR. Erratum: Crystal structures of eosinophil-derived neurotoxin (EDN) in complex with the inhibitors 5′-ATP, Ap3A, Ap4A, and Ap5A (Biochemistry (January 17, 2006) 45, 2 (416-426)) Biochemistry. 45. DOI: 10.1021/Bi068008U  0.36
2005 Sundara Baalaji N, Acharya KR, Singh TP, Krishnaswamy S. High-resolution diffraction from crystals of a membrane-protein complex: bacterial outer membrane protein OmpC complexed with the antibacterial eukaryotic protein lactoferrin. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 61: 773-5. PMID 16511154 DOI: 10.1107/S1744309105022086  1
2005 Swaminathan GJ, Myszka DG, Katsamba PS, Ohnuki LE, Gleich GJ, Acharya KR. Eosinophil-granule major basic protein, a C-type lectin, binds heparin. Biochemistry. 44: 14152-8. PMID 16245931 DOI: 10.1021/Bi051112B  1
2005 Balyasnikova IV, Woodman ZL, Albrecht RF, Natesh R, Acharya KR, Sturrock ED, Danilov SM. Localization of an N-domain region of angiotensin-converting enzyme involved in the regulation of ectodomain shedding using monoclonal antibodies. Journal of Proteome Research. 4: 258-67. PMID 15822901 DOI: 10.1021/Pr049859W  1
2005 Acharya KR, Lloyd MD. The advantages and limitations of protein crystal structures. Trends in Pharmacological Sciences. 26: 10-4. PMID 15629199 DOI: 10.1016/J.Tips.2004.10.011  1
2005 Lloyd MD, Pederick RL, Natesh R, Woo LW, Purohit A, Reed MJ, Acharya KR, Potter BV. Crystal structure of human carbonic anhydrase II at 1.95 A resolution in complex with 667-coumate, a novel anti-cancer agent. The Biochemical Journal. 385: 715-20. PMID 15453828 DOI: 10.1042/Bj20041037  1
2004 Baker MD, Gendlina I, Collins CM, Acharya KR. Crystal structure of a dimeric form of streptococcal pyrogenic exotoxin A (SpeA1). Protein Science : a Publication of the Protein Society. 13: 2285-90. PMID 15295110 DOI: 10.1110/Ps.04826804  1
2004 Errico M, Riccioni T, Iyer S, Pisano C, Acharya KR, Persico MG, De Falco S. Identification of placenta growth factor determinants for binding and activation of Flt-1 receptor. The Journal of Biological Chemistry. 279: 43929-39. PMID 15272021 DOI: 10.1074/Jbc.M401418200  1
2004 Natesh R, Schwager SLU, Evans HR, Sturrock ED, Acharya KR. Structural details on the binding of antihypertensive drugs captopril and enalaprilat to human testicular angiotensin I-converting enzyme Biochemistry. 43: 8718-8724. PMID 15236580 DOI: 10.1021/Bi049480N  1
2004 Zhang Y, Deshpande A, Xie Z, Natesh R, Acharya KR, Brew K. Roles of active site tryptophans in substrate binding and catalysis by alpha-1,3 galactosyltransferase. Glycobiology. 14: 1295-302. PMID 15229192 DOI: 10.1093/Glycob/Cwh119  1
2004 Baker MD, Acharya KR. Superantigens: Structure-function relationships International Journal of Medical Microbiology. 293: 529-537. PMID 15149028 DOI: 10.1078/1438-4221-00298  1
2004 Papageorgiou AC, Baker MD, McLeod JD, Goda SK, Manzotti CN, Sansom DM, Tranter HS, Acharya KR. Identification of a secondary zinc-binding site in staphylococcal enterotoxin C2. Implications for superantigen recognition. The Journal of Biological Chemistry. 279: 1297-303. PMID 14559915 DOI: 10.1074/Jbc.M307333200  1
2003 Acharya KR, Sturrock ED, Riordan JF, Ehlers MR. Ace revisited: a new target for structure-based drug design. Nature Reviews. Drug Discovery. 2: 891-902. PMID 14668810 DOI: 10.1038/Nrd1227  1
2003 Zhang Y, Swaminathan GJ, Deshpande A, Boix E, Natesh R, Xie Z, Acharya KR, Brew K. Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity. Biochemistry. 42: 13512-21. PMID 14621997 DOI: 10.1021/Bi035430R  1
2003 Guy JL, Jackson RM, Acharya KR, Sturrock ED, Hooper NM, Turner AJ. Angiotensin-converting enzyme-2 (ACE2): comparative modeling of the active site, specificity requirements, and chloride dependence. Biochemistry. 42: 13185-92. PMID 14609329 DOI: 10.1021/Bi035268S  1
2003 Evans HR, Sutton JM, Holloway DE, Ayriss J, Shone CC, Acharya KR. The Crystal Structure of C3stau2 from Staphylococcus aureus and Its Complex with NAD Journal of Biological Chemistry. 278: 45924-45930. PMID 12933793 DOI: 10.1074/Jbc.M307719200  1
2003 Chavali GB, Papageorgiou AC, Olson KA, Fett JW, Hu GF, Shapiro R, Acharya KR. The crystal structure of human angiogenin in complex with an antitumor neutralizing antibody Structure. 11: 875-885. PMID 12842050 DOI: 10.1016/S0969-2126(03)00131-X  1
2003 Swaminathan GJ, Holloway DE, Colvin RA, Campanella GK, Papageorgiou AC, Luster AD, Acharya KR. Crystal structures of oligomeric forms of the IP-10/CXCL10 chemokine. Structure (London, England : 1993). 11: 521-32. PMID 12737818 DOI: 10.1016/S0969-2126(03)00070-4  1
2003 Gordon K, Redelinghuys P, Schwager SL, Ehlers MR, Papageorgiou AC, Natesh R, Acharya KR, Sturrock ED. Deglycosylation, processing and crystallization of human testis angiotensin-converting enzyme. The Biochemical Journal. 371: 437-42. PMID 12542396 DOI: 10.1042/Bj20021842  1
2002 Mohan CG, Boix E, Evans HR, Nikolovski Z, Nogués MV, Cuchillo CM, Acharya KR. The crystal structure of eosinophil cationic protein in complex with 2′,5′-ADP at 2.0 Å resolution reveals the details of the ribonucleolytic active site Biochemistry. 41: 12100-12106. PMID 12356310 DOI: 10.1021/Bi0264521  1
2002 Boix E, Zhang Y, Swaminathan GJ, Brew K, Acharya KR. Structural basis of ordered binding of donor and acceptor substrates to the retaining glycosyltransferase, alpha-1,3-galactosyltransferase. The Journal of Biological Chemistry. 277: 28310-8. PMID 12011052 DOI: 10.1074/Jbc.M202631200  0.72
2002 Iyer S, Acharya KR. Role of placenta growth factor in cardiovascular health Trends in Cardiovascular Medicine. 12: 128-134. PMID 12007738 DOI: 10.1016/S1050-1738(01)00164-5  1
2002 Ackerman SJ, Liu L, Kwatia MA, Savage MP, Leonidas DD, Swaminathan GJ, Acharya KR. Charcot-Leyden crystal protein (galectin-10) is not a dual function galectin with lysophospholipase activity but binds a lysophospholipase inhibitor in a novel structural fashion. The Journal of Biological Chemistry. 277: 14859-68. PMID 11834744 DOI: 10.1074/Jbc.M200221200  0.36
2001 Holloway DE, Hares MC, Shapiro R, Subramanian V, Acharya KR. High-level expression of three members of the murine angiogenin family in Escherichia coli and purification of the recombinant proteins Protein Expression and Purification. 22: 307-317. PMID 11437607 DOI: 10.1006/Prep.2001.1434  1
2001 Baker M, Gutman DM, Papageorgiou AC, Collins CM, Acharya KR. Structural features of a zinc binding site in the superantigen strepococcal pyrogenic exotoxin A (SpeA1): implications for MHC class II recognition. Protein Science : a Publication of the Protein Society. 10: 1268-73. PMID 11369867 DOI: 10.1110/Ps.330101  1
2000 Papageorgiou AC, Acharya KR. Microbial superantigens: From structure to function Trends in Microbiology. 8: 369-375. PMID 10920396 DOI: 10.1016/S0966-842X(00)01793-5  1
1999 Boix E, Leonidas DD, Nikolovski Z, Nogués MV, Cuchillo CM, Acharya KR. Crystal structure of eosinophil cationic protein at 2.4 A resolution Biochemistry. 38: 16794-16801. PMID 10606511 DOI: 10.1021/Bi9919145  1
1999 Swaminathan GJ, Leonidas DD, Savage MP, Ackerman SJ, Acharya KR. Selective recognition of mannose by the human eosinophil Charcot-Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution. Biochemistry. 38: 13837-43. PMID 10529229 DOI: 10.1021/Bi990756E  1
1999 Vatzaki EH, Allen SC, Leonidas DD, Trautwein-Fritz K, Stackhouse J, Benner SA, Acharya KR. Crystal structure of a hybrid between ribonuclease A and bovine seminal ribonuclease--the basic surface, at 2.0 A resolution. European Journal of Biochemistry / Febs. 260: 176-82. PMID 10091597 DOI: 10.1046/J.1432-1327.1999.00142.X  1
1999 Papageorgiou AC, Collins CM, Gutman DM, Kline JB, O'Brien SM, Tranter HS, Acharya KR. Structural basis for the recognition of superantigen streptococcal pyrogenic exotoxin A (SpeA1) by MHC class II molecules and T-cell receptors. The Embo Journal. 18: 9-21. PMID 9878045 DOI: 10.1093/Emboj/18.1.9  1
1998 Chandra N, Brew K, Acharya KR. Structural evidence for the presence of a secondary calcium binding site in human alpha-lactalbumin. Biochemistry. 37: 4767-72. PMID 9537992 DOI: 10.1021/Bi973000T  1
1997 Papageorgiou AC, Acharya KR. Superantigens as immunomodulators: Recent structural insights Structure. 5: 991-996. PMID 9309216 DOI: 10.1016/S0969-2126(97)00252-9  1
1997 Schad EM, Papageorgiou AC, Svensson LA, Acharya KR. A structural and functional comparison of staphylococcal enterotoxins A and C2 reveals remarkable similarity and dissimilarity Journal of Molecular Biology. 269: 270-280. PMID 9191070 DOI: 10.1006/Jmbi.1997.1023  1
1996 Papageorgiou AC, Quinn CP, Beer D, Brehm RD, Tranter HS, Bonventre PF, Acharya KR. Crystal structure of a biologically inactive mutant of toxic shock syndrome toxin-1 at 2.5 Å resolution Protein Science. 5: 1737-1741. PMID 8844860 DOI: 10.1002/Pro.5560050826  1
1996 Pike ACW, Brew K, Acharya KR. Crystal structures of guinea-pig, goat and bovine α-lactalbumin highlight the enhanced conformational flexibility of regions that are significant for its action in lactose synthase Structure. 4: 691-703. PMID 8805552 DOI: 10.1016/S0969-2126(96)00075-5  1
1996 Kontou M, Vatzaki EH, Kokla A, Acharya KR, Oikonomakos NG, Tzartos SJ. Characterisation, crystallisation and preliminary X-ray diffraction analysis of a Fab fragment of a rat monoclonal antibody with very high affinity for the human muscle acetylcholine receptor Febs Letters. 389: 195-198. PMID 8766828 DOI: 10.1016/0014-5793(96)00579-0  1
1995 Leonidas DD, Elbert BL, Zhou Z, Leffler H, Ackerman SJ, Acharya KR. Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. Structure (London, England : 1993). 3: 1379-93. PMID 8747464 DOI: 10.1016/S0969-2126(01)00275-1  1
1995 Papageorgiou AC, Acharya KR, Shapiro R, Passalacqua EF, Brehm RD, Tranter HS. Crystal structure of the superantigen enterotoxin C2 from Staphylococcus aureus reveals a zinc-binding site Structure. 3: 769-779. PMID 7582894 DOI: 10.1016/S0969-2126(01)00212-X  1
1994 Pike ACW, Acharya KR. A structural basis for the interaction of urea with lysozyme Protein Science. 3: 706-710. PMID 8003989 DOI: 10.1002/Pro.5560030419  1
1994 Acharya KR, Stuart DI, Phillips DC, McKenzie HA, Teahan CG. Models of the three-dimensional structures of echidna, horse, and pigeon lysozymes: calcium-binding lysozymes and their relationship with alpha-lactalbumins. Journal of Protein Chemistry. 13: 569-84. PMID 7832986 DOI: 10.1007/Bf01901539  1
1994 Allen SC, Acharya KR, Palmer KA, Shapiro R, Vallee BL, Scheraga HA. A comparison of the predicted and X-ray structures of angiogenin. Implications for further studies of model building of homologous proteins. Journal of Protein Chemistry. 13: 649-58. PMID 7702747 DOI: 10.1007/Bf01890464  1
1993 Passalacqua EF, Brehm RD, Acharya KR, Tranter HS. Crystallization and preliminary X-ray analysis of a microbial superantigen staphylococcal enterotoxin C2 Journal of Molecular Biology. 233: 170-172. PMID 8377185 DOI: 10.1006/Jmbi.1993.1493  1
1993 Vatzaki EH, Acharya KR, Oikonomakos NG, Tzartos SJ. Crystallization and preliminary crystallographic study of an Fab fragment of a pathogenic rat monoclonal antibody against the nicotinic acetylcholine receptor Protein Science. 2: 1770-1772. PMID 8251949 DOI: 10.1002/Pro.5560021021  1
1993 Robson KJ, Gamble Y, Acharya KR. Molecular modelling of malaria calmodulin suggests that it is not a suitable target for novel antimalarials Philosophical Transactions of the Royal Society of London. Series B: Biological Sciences. 340: 39-53. PMID 8099744 DOI: 10.1098/Rstb.1993.0047  1
1992 Acharya KR, Subramanian V, Shapiro R, Riordan JF, Vallee BL. Crystallization and preliminary X-ray analysis of human angiogenin Journal of Molecular Biology. 228: 1269-1270. PMID 1474591 DOI: 10.1016/0022-2836(92)90333-F  1
1992 Passalacqua EF, Brehm RD, Acharya KR, Tranter HS. Purification, crystallization and preliminary X-ray analysis of toxic shock syndrome toxin-1 from Staphylococcus aureus Journal of Molecular Biology. 228: 983-986. PMID 1469731 DOI: 10.1016/0022-2836(92)90882-K  1
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