| Year |
Citation |
Score |
| 2023 |
Xu Q, Streuer A, Jann JC, Altrock E, Schmitt N, Flach J, Sens-Albert C, Rapp F, Wolf J, Nowak V, Weimer N, Obländer J, Palme I, Kuzina M, Jawhar A, et al. Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies. Nature Communications. 14: 1497. PMID 36932114 DOI: 10.1038/s41467-023-37175-8 |
0.306 |
|
| 2021 |
Ho TT, Dellorusso PV, Verovskaya EV, Bakker ST, Flach J, Smith LK, Ventura PB, Lansinger OM, Hérault A, Zhang SY, Kang YA, Mitchell CA, Villeda SA, Passegué E. Aged hematopoietic stem cells are refractory to bloodborne systemic rejuvenation interventions. The Journal of Experimental Medicine. 218. PMID 34032859 DOI: 10.1084/jem.20210223 |
0.674 |
|
| 2020 |
Christopeit M, Badbaran A, Alawi M, Flach J, Fehse B, Kröger N. Clonal evolution after allogeneic stem cell transplantation: the case of myelofibrosis. Biology of Blood and Marrow Transplantation : Journal of the American Society For Blood and Marrow Transplantation. PMID 32147533 DOI: 10.1016/j.bbmt.2020.02.021 |
0.32 |
|
| 2019 |
Jann JC, Nolte F, Mossner M, Flach J, Altrock E, Schmitt N, Röhl H, Jawhar A, Neumann U, Nowak V, Danner J, Obländer J, Palme I, Hofmann WK, Nowak D. Comparative analysis of clonal hematopoiesis of multipotent stem cells in healthy elderly in blood and bone marrow. Leukemia Research. 82: 15-18. PMID 31132434 DOI: 10.1016/j.leukres.2019.05.005 |
0.384 |
|
| 2019 |
Altrock E, Sens-Albert C, Jann J, Flach J, Ryabov V, Schmitt N, Streuer A, Xu Q, Nowak V, Danner J, Obländer J, Draeger N, Palme I, Jawhar A, Weis C, et al. Comparison of Four Different Humanized Hematopoietic Niche Xenotransplantation Methods to Engraft Myelodysplastic Syndromes (MDS) Blood. 134: 4227-4227. DOI: 10.1182/blood-2019-128075 |
0.304 |
|
| 2018 |
Flach J, Milyavsky M. Replication stress in hematopoietic stem cells in mouse and man. Mutation Research. 808: 74-82. PMID 29079268 DOI: 10.1016/j.mrfmmm.2017.10.001 |
0.434 |
|
| 2017 |
Ho TT, Warr MR, Adelman ER, Lansinger OM, Flach J, Verovskaya EV, Figueroa ME, Passegué E. Autophagy maintains the metabolism and function of young and old stem cells. Nature. PMID 28241143 DOI: 10.1038/Nature21388 |
0.756 |
|
| 2016 |
Wang W, Org T, Montel-Hagen A, Pioli PD, Duan D, Israely E, Malkin D, Su T, Flach J, Kurdistani SK, Schiestl RH, Mikkola HK. MEF2C protects bone marrow B-lymphoid progenitors during stress haematopoiesis. Nature Communications. 7: 12376. PMID 27507714 DOI: 10.1038/Ncomms12376 |
0.384 |
|
| 2015 |
Alvarez S, Díaz M, Flach J, Rodriguez-Acebes S, López-Contreras AJ, Martínez D, Cañamero M, Fernández-Capetillo O, Isern J, Passegué E, Méndez J. Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. Nature Communications. 6: 8548. PMID 26456157 DOI: 10.1038/Ncomms9548 |
0.716 |
|
| 2015 |
Wong JC, Weinfurtner KM, Alzamora MD, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen SC, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, et al. Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis. Elife. 4. PMID 26193121 DOI: 10.7554/Elife.07839 |
0.768 |
|
| 2015 |
Buchner M, Park E, Geng H, Klemm L, Flach J, Passegué E, Schjerven H, Melnick A, Paietta E, Kopanja D, Raychaudhuri P, Müschen M. Identification of FOXM1 as a therapeutic target in B-cell lineage acute lymphoblastic leukaemia. Nature Communications. 6: 6471. PMID 25753524 DOI: 10.1038/Ncomms7471 |
0.63 |
|
| 2015 |
Wong JC, Weinfurtner KM, Alzamora Mdp, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen S, Ho TT, Flach J, Reynaud D, Passegué E, Downing JR, et al. Author response: Functional evidence implicating chromosome 7q22 haploinsufficiency in myelodysplastic syndrome pathogenesis Elife. DOI: 10.7554/Elife.07839.010 |
0.734 |
|
| 2014 |
Flach J, Bakker ST, Mohrin M, Conroy PC, Pietras EM, Reynaud D, Alvarez S, Diolaiti ME, Ugarte F, Forsberg EC, Le Beau MM, Stohr BA, Méndez J, Morrison CG, Passegué E. Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells. Nature. 512: 198-202. PMID 25079315 DOI: 10.1038/Nature13619 |
0.751 |
|
| 2014 |
Pietras EM, Lakshminarasimhan R, Techner JM, Fong S, Flach J, Binnewies M, Passegué E. Re-entry into quiescence protects hematopoietic stem cells from the killing effect of chronic exposure to type I interferons. The Journal of Experimental Medicine. 211: 245-62. PMID 24493802 DOI: 10.1084/Jem.20131043 |
0.764 |
|
| 2014 |
Wong JC, Weinfurtner K, Alzamora P, Kogan SC, Burgess MR, Zhang Y, Nakitandwe J, Ma J, Cheng J, Chen S, Flach J, Reynaud D, Passegue E, Downing JR, Shannon K. Aberrant Hematopoietic Stem Cell Function in Mice Haploinsufficient for a 2 Mb Deletion of Chromosome 5A3 Syntenic to a Region of Human 7q22 Frequently Deleted in Myelodysplastic Syndromes Blood. 124: 3247-3247. DOI: 10.1182/Blood.V124.21.3247.3247 |
0.806 |
|
| 2013 |
Schepers K, Pietras EM, Reynaud D, Flach J, Binnewies M, Garg T, Wagers AJ, Hsiao EC, Passegué E. Myeloproliferative neoplasia remodels the endosteal bone marrow niche into a self-reinforcing leukemic niche. Cell Stem Cell. 13: 285-99. PMID 23850243 DOI: 10.1016/J.Stem.2013.06.009 |
0.755 |
|
| 2013 |
Warr MR, Binnewies M, Flach J, Reynaud D, Garg T, Malhotra R, Debnath J, Passegué E. FOXO3A directs a protective autophagy program in haematopoietic stem cells. Nature. 494: 323-7. PMID 23389440 DOI: 10.1038/Nature11895 |
0.756 |
|
| 2012 |
Flach J, Bakker S, Conroy P, Reynaud D, Le Beau MM, Morrison C, Passegué E. Increased γH2AX Foci in Old Hematopoietic Stem Cells Are Independent of the DNA Damage Response and Linked to Inefficient DNA Replication/Transcription Blood. 120: 1207-1207. DOI: 10.1182/Blood.V120.21.1207.1207 |
0.773 |
|
| 2009 |
Flach J, Schindela S, Dicker F, Schnittger S, Kazak B, Kohlmann A, Kern W, Haferlach T, Haferlach C. An Accumulation of Cytogenetic and Molecular Genetic Events Characterizes the Progression From MDS to Secondary AML: An Analysis of Paired Samples in 38 Patients Analyzed by Cytogenetics, Mutation Analysis and SNP Microarrays. Blood. 114: 1748-1748. DOI: 10.1182/Blood.V114.22.1748.1748 |
0.309 |
|
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