Ka-Chun Wong - Publications

Affiliations: 
2011-2014 Computer Science University of Toronto, Toronto, ON, Canada 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yan S, Wong KC. Context awareness and embedding for biomedical event extraction. Bioinformatics (Oxford, England). PMID 31392318 DOI: 10.1093/bioinformatics/btz607  0.64
2019 Wong KC, Chen J, Zhang J, Lin J, Yan S, Zhang S, Li X, Liang C, Peng C, Lin Q, Kwong S, Yu J. Early Cancer Detection from Multianalyte Blood Test Results. Iscience. 15: 332-341. PMID 31103852 DOI: 10.1016/j.isci.2019.04.035  1
2019 Wang Y, Liu B, Ma Z, Wong KC, Li X. Nature-Inspired Multiobjective Cancer Subtype Diagnosis. Ieee Journal of Translational Engineering in Health and Medicine. 7: 4300112. PMID 30915261 DOI: 10.1109/JTEHM.2019.2891746  1
2019 Li X, Wong KC. Single-Cell RNA Sequencing Data Interpretation by Evolutionary Multiobjective Clustering. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 30908236 DOI: 10.1109/TCBB.2019.2906601  1
2019 Yan S, Wong KC. GESgnExt: Gene Expression Signature Extraction and Meta-analysis on Gene Expression Omnibus. Ieee Journal of Biomedical and Health Informatics. PMID 30714937 DOI: 10.1109/JBHI.2019.2896144  0.64
2018 Li X, Zhang S, Wong KC. Single-cell RNA-seq Interpretations using Evolutionary Multiobjective Ensemble Pruning. Bioinformatics (Oxford, England). PMID 30596898 DOI: 10.1093/bioinformatics/bty1056  1
2018 Wong KC, Lin J, Li X, Lin Q, Liang C, Song YQ. Heterodimeric DNA motif synthesis and validations. Nucleic Acids Research. PMID 30590725 DOI: 10.1093/nar/gky1297  1
2018 Liang C, Yu S, Wong KC, Luo J. A novel semi-supervised model for miRNA-disease association prediction based on [Formula: see text]-norm graph. Journal of Translational Medicine. 16: 357. PMID 30547813 DOI: 10.1186/s12967-018-1741-y  0.52
2018 Wong KC, Yan S, Lin Q, Li X, Peng C. Deleterious Non-Synonymous Single Nucleotide Polymorphism Predictions on Human Transcription Factors. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 30475727 DOI: 10.1109/TCBB.2018.2882548  1
2018 Lin J, Wong KC. Off-target predictions in CRISPR-Cas9 gene editing using deep learning. Bioinformatics (Oxford, England). 34: i656-i663. PMID 30423072 DOI: 10.1093/bioinformatics/bty554  0.48
2018 Zhang S, Li X, Lin Q, Wong KC. Synergizing CRISPR/Cas9 Off-Target Predictions for Ensemble Insights and Practical Applications. Bioinformatics (Oxford, England). PMID 30169558 DOI: 10.1093/bioinformatics/bty748  1
2018 Li X, Zhang S, Wong KC. Nature-Inspired Multiobjective Epistasis Elucidation from Genome-Wide Association Studies. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 29994485 DOI: 10.1109/TCBB.2018.2849759  1
2018 Zhang J, Kwong S, Liu G, Lin Q, Wong KC. PathEmb: Random Walk based Document Embedding for Global Pathway Similarity Search. Ieee Journal of Biomedical and Health Informatics. PMID 29993756 DOI: 10.1109/JBHI.2018.2830806  0.64
2018 Li X, Wong KC. Evolutionary Multiobjective Clustering and Its Applications to Patient Stratification. Ieee Transactions On Cybernetics. PMID 29993679 DOI: 10.1109/TCYB.2018.2817480  1
2018 Ho MX, Poon CC, Wong KC, Qiu ZC, Wong MS. Icariin, but Not Genistein, Exerts Osteogenic and Anti-apoptotic Effects in Osteoblastic Cells by Selective Activation of Non-genomic ERα Signaling. Frontiers in Pharmacology. 9: 474. PMID 29867480 DOI: 10.3389/fphar.2018.00474  0.56
2018 Cao L, Wang S, Zhang Y, Wong KC, Nakatsu G, Wang X, Wong S, Ji J, Yu J. Zinc-finger protein 471 suppresses gastric cancer through transcriptionally repressing downstream oncogenic PLS3 and TFAP2A. Oncogene. PMID 29610526 DOI: 10.1038/s41388-018-0220-5  0.44
2018 Cao S, Dong XL, Ho MX, Yu WX, Wong KC, Yao XS, Wong MS. Oleanolic Acid Exerts Osteoprotective Effects and Modulates Vitamin D Metabolism. Nutrients. 10. PMID 29470404 DOI: 10.3390/nu10020247  0.56
2018 Wei P, Ning Z, Ye S, Sun L, Yang F, Wong KC, Westerdahl D, Louie PKK. Impact Analysis of Temperature and Humidity Conditions on Electrochemical Sensor Response in Ambient Air Quality Monitoring. Sensors (Basel, Switzerland). 18. PMID 29360749 DOI: 10.3390/s18020059  0.68
2017 Li X, Wong KC. Elucidating Genome-Wide Protein-RNA Interactions using Differential Evolution. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 29990254 DOI: 10.1109/TCBB.2017.2776224  1
2017 Li X, Wong KC. Multiobjective Patient Stratification using Evolutionary Multiobjective Optimization. Ieee Journal of Biomedical and Health Informatics. PMID 29990162 DOI: 10.1109/JBHI.2017.2769711  1
2017 Zhang J, Kwong S, Wong KC. ToBio: Global Pathway Similarity Search based on Topological and Biological Features. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 29990160 DOI: 10.1109/TCBB.2017.2769642  0.64
2017 Sun W, Zhang Y, Wong KC, Liu K, Yang Y, Wu B, Tong JH, Chan AW, Chan HL, Yu J. Increased expression of GATA Zinc Finger Domain Containing 1 via gene amplification promotes liver cancer by directly inducing PRL3. Hepatology (Baltimore, Md.). PMID 29266303 DOI: 10.1002/hep.29750  0.44
2017 Lin Q, Jin G, Ma Y, Wong KC, Coello Coello CA, Li J, Chen J, Zhang J. A Diversity-Enhanced Resource Allocation Strategy for Decomposition-Based Multiobjective Evolutionary Algorithm. Ieee Transactions On Cybernetics. PMID 28885164 DOI: 10.1109/TCYB.2017.2739185  0.64
2017 Yan S, Wong KC. Elucidating high-dimensional cancer hallmark annotation via enriched ontology. Journal of Biomedical Informatics. PMID 28723579 DOI: 10.1016/j.jbi.2017.07.011  0.64
2017 Li X, Ma S, Wong KC. Evolving Spatial Clusters of Genomic Regions from High-Throughput Chromatin Conformation Capture data. Ieee Transactions On Nanobioscience. PMID 28708563 DOI: 10.1109/TNB.2017.2725991  1
2017 Zhu Q, Lin Q, Chen W, Wong KC, Coello Coello CA, Li J, Chen J, Zhang J. An External Archive-Guided Multiobjective Particle Swarm Optimization Algorithm. Ieee Transactions On Cybernetics. PMID 28613192 DOI: 10.1109/TCYB.2017.2710133  0.64
2017 Wong KC, Cao S, Dong X, Law MC, Chan TH, Wong MS. (-)-Epiafzelechin Protects against Ovariectomy-induced Bone Loss in Adult Mice and Modulate Osteoblastic and Osteoclastic Functions In Vitro. Nutrients. 9. PMID 28531166 DOI: 10.3390/nu9050530  0.56
2017 Li X, Wong KC. A Comparative Study for Identifying the Chromosome-Wide Spatial Clusters from High-Throughput Chromatin Conformation Capture data. Ieee/Acm Transactions On Computational Biology and Bioinformatics. PMID 28333638 DOI: 10.1109/TCBB.2017.2684800  1
2017 Zhang J, Kwong S, Jia Y, Wong KC. NSSRF: global network similarity search with subgraph signatures and its applications. Bioinformatics (Oxford, England). PMID 28158419 DOI: 10.1093/bioinformatics/btx051  0.64
2016 Qiu ZC, Dong XL, Dai Y, Xiao GK, Wang XL, Wong KC, Wong MS, Yao XS. Discovery of a New Class of Cathepsin K Inhibitors in Rhizoma Drynariae as Potential Candidates for the Treatment of Osteoporosis. International Journal of Molecular Sciences. 17. PMID 27999266 DOI: 10.3390/ijms17122116  0.56
2016 Wong KC, Peng C, Yan S, Liang C. Probabilistic Inference on Multiple Normalized Genome-Wide Signal Profiles with Model Regularization. Ieee Transactions On Nanobioscience. PMID 27893398 DOI: 10.1109/TNB.2016.2631406  0.8
2016 Wong KC, Li Y, Peng C, Wong HS. A Comparison Study for DNA Motif Modeling on Protein Binding Microarray. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 13: 261-271. PMID 27045826 DOI: 10.1109/TCBB.2015.2443782  0.8
2016 Wong KC, Peng C, Li Y. Evolving Transcription Factor Binding Site Models From Protein Binding Microarray Data. Ieee Transactions On Cybernetics. PMID 26887021 DOI: 10.1109/TCYB.2016.2519380  0.8
2016 Sun L, Wong KC, Wei P, Ye S, Huang H, Yang F, Westerdahl D, Louie PK, Luk CW, Ning Z. Development and Application of a Next Generation Air Sensor Network for the Hong Kong Marathon 2015 Air Quality Monitoring. Sensors (Basel, Switzerland). 16. PMID 26861336 DOI: 10.3390/s16020211  0.4
2015 Wong KC, Peng C, Li Y. Probabilistic Inference on Multiple Normalized Signal Profiles from Next Generation Sequencing: Transcription Factor Binding Sites. Ieee/Acm Transactions On Computational Biology and Bioinformatics / Ieee, Acm. 12: 1416-28. PMID 26671811 DOI: 10.1109/TCBB.2015.2424421  0.8
2015 Wong KC, Li Y, Peng C, Moses AM, Zhang Z. Computational learning on specificity-determining residue-nucleotide interactions. Nucleic Acids Research. PMID 26527718 DOI: 10.1093/nar/gkv1134  0.8
2015 Wong KC, Li Y, Peng C. Identification of Coupling DNA Motif Pairs on Long-Range Chromatin Interactions in Human K562 Cells. Bioinformatics (Oxford, England). PMID 26411866 DOI: 10.1093/bioinformatics/btv555  0.8
2015 Xiao HH, Gao QG, Ho MX, Zhang Y, Wong KC, Dai Y, Yao XS, Wong MS. An 8-O-4' norlignan exerts oestrogen-like actions in osteoblastic cells via rapid nongenomic ER signaling pathway. Journal of Ethnopharmacology. 170: 39-49. PMID 25978953 DOI: 10.1016/j.jep.2015.05.012  0.32
2015 Wong KC, Li Y, Peng C, Zhang Z. SignalSpider: probabilistic pattern discovery on multiple normalized ChIP-Seq signal profiles. Bioinformatics (Oxford, England). 31: 17-24. PMID 25192742 DOI: 10.1093/bioinformatics/btu604  0.8
2014 Cromar G, Wong KC, Loughran N, On T, Song H, Xiong X, Zhang Z, Parkinson J. New tricks for "old" domains: how novel architectures and promiscuous hubs contributed to the organization and evolution of the ECM. Genome Biology and Evolution. 6: 2897-917. PMID 25323955 DOI: 10.1093/gbe/evu228  0.8
2014 Wong KC, Law MC, Wong MS, Chan TH. Development of a UPLC-MS/MS bioanalytical method for the pharmacokinetic study of (-)-epiafzelechin, a flavan-3-ol with osteoprotective activity, in C57BL/6J mice. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 967: 162-7. PMID 25108364 DOI: 10.1016/j.jchromb.2014.07.028  0.56
2014 Li Y, Liang C, Wong KC, Luo J, Zhang Z. Mirsynergy: detecting synergistic miRNA regulatory modules by overlapping neighbourhood expansion. Bioinformatics (Oxford, England). 30: 2627-35. PMID 24894504 DOI: 10.1093/bioinformatics/btu373  0.8
2014 Wong KC, Lee KS, Luk HK, Wan HY, Ho CK, Zhang Y, Wong MS. Er-xian Decoction exerts estrogen-like osteoprotective effects in vivo and in vitro. The American Journal of Chinese Medicine. 42: 409-26. PMID 24707871 DOI: 10.1142/S0192415X1450027X  0.56
2014 Li Y, Liang C, Wong KC, Jin K, Zhang Z. Inferring probabilistic miRNA-mRNA interaction signatures in cancers: a role-switch approach. Nucleic Acids Research. 42: e76. PMID 24609385 DOI: 10.1093/nar/gku182  0.8
2014 Xiao HH, Fung CY, Mok SK, Wong KC, Ho MX, Wang XL, Yao XS, Wong MS. Flavonoids from Herba epimedii selectively activate estrogen receptor alpha (ERα) and stimulate ER-dependent osteoblastic functions in UMR-106 cells. The Journal of Steroid Biochemistry and Molecular Biology. 143: 141-51. PMID 24607839 DOI: 10.1016/j.jsbmb.2014.02.019  0.56
2014 Wong KC, Zhang Z. SNPdryad: predicting deleterious non-synonymous human SNPs using only orthologous protein sequences. Bioinformatics (Oxford, England). PMID 24389653 DOI: 10.1093/bioinformatics/btt769  0.8
2014 Li Y, Goldenberg A, Wong KC, Zhang Z. A probabilistic approach to explore human miRNA targetome by integrating miRNA-overexpression data and sequence information. Bioinformatics (Oxford, England). 30: 621-8. PMID 24135265 DOI: 10.1093/bioinformatics/btt599  0.8
2013 Wong KC, Chan TM, Peng C, Li Y, Zhang Z. DNA motif elucidation using belief propagation. Nucleic Acids Research. 41: e153. PMID 23814189 DOI: 10.1093/nar/gkt574  0.8
2013 Wong KC, Pang WY, Wang XL, Mok SK, Lai WP, Chow HK, Leung PC, Yao XS, Wong MS. Drynaria fortunei-derived total flavonoid fraction and isolated compounds exert oestrogen-like protective effects in bone. The British Journal of Nutrition. 110: 475-85. PMID 23302510 DOI: 10.1017/S0007114512005405  0.56
2012 Fan M, Wong KC, Ryu T, Ravasi T, Gao X. SECOM: a novel hash seed and community detection based-approach for genome-scale protein domain identification. Plos One. 7: e39475. PMID 22761802 DOI: 10.1371/journal.pone.0039475  0.8
2012 Peng C, Jin X, Wong KC, Shi M, Liò P. Collective human mobility pattern from taxi trips in urban area. Plos One. 7: e34487. PMID 22529917 DOI: 10.1371/journal.pone.0034487  0.8
2011 Chan TM, Wong KC, Lee KH, Wong MH, Lau CK, Tsui SK, Leung KS. Discovering approximate-associated sequence patterns for protein-DNA interactions. Bioinformatics (Oxford, England). 27: 471-8. PMID 21193520 DOI: 10.1093/bioinformatics/btq682  0.32
2010 Leung KS, Wong KC, Chan TM, Wong MH, Lee KH, Lau CK, Tsui SK. Discovering protein-DNA binding sequence patterns using association rule mining. Nucleic Acids Research. 38: 6324-37. PMID 20529874 DOI: 10.1093/nar/gkq500  0.32
2009 Zhao Y, Woo KS, Ma KH, van Hansselt CA, Wong KC, Cheng KF, Lam CW, Leung PC. Treatment of perennial allergic rhinitis using Shi-Bi-Lin, a Chinese herbal formula. Journal of Ethnopharmacology. 122: 100-5. PMID 19118617 DOI: 10.1016/j.jep.2008.12.005  0.56
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