Sumedha Gunewardena - Publications

2005-2008 University of Toronto, Toronto, ON, Canada 

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Schonfeld M, O'Neil M, Villar MT, Artigues A, Averilla J, Gunewardena S, Weinman SA, Tikhanovich I. A Western diet with alcohol in drinking water model recapitulates features of alcohol-associated liver disease in mice. Alcoholism, Clinical and Experimental Research. PMID 34523155 DOI: 10.1111/acer.14700  1
2021 Provance OK, Geanes ES, Lui AJ, Roy A, Holloran S, Gunewardena S, Hagan C, Weir S, Lewis-Wambi J. Disrupting interferon-alpha and NF-kappaB crosstalk suppresses IFITM1 expression attenuating triple-negative breast cancer progression. Cancer Letters. PMID 34022283 DOI: 10.1016/j.canlet.2021.05.006  0.01
2021 Das A, Haque I, Ray P, Ghosh A, Dutta D, Quadir M, De A, Gunewardena S, Chatterjee I, Banerjee S, Weir S, Banerjee SK. CCN5 activation by free or encapsulated EGCG is required to render triple-negative breast cancer cell viability and tumor progression. Pharmacology Research & Perspectives. 9: e00753. PMID 33745223 DOI: 10.1002/prp2.753  1
2021 Zhang X, Gunewardena S, Wang N. Nutrient restriction synergizes with retinoic acid to induce mammalian meiotic initiation in vitro. Nature Communications. 12: 1758. PMID 33741948 DOI: 10.1038/s41467-021-22021-6  0.56
2021 Sharma M, Yerrathota S, Thornton MM, Gunewardena S. Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice. Data in Brief. 35: 106873. PMID 33665264 DOI: 10.1016/j.dib.2021.106873  1
2021 Rafi SK, Goering JP, Olm-Shipman AJ, Hipp LA, Ernst NJ, Wilson NR, Hall EG, Gunewardena S, Saadi I. Anti-epileptic drug topiramate upregulates TGFβ1 and SOX9 expression in primary embryonic palatal mesenchyme cells: Implications for teratogenicity. Plos One. 16: e0246989. PMID 33577554 DOI: 10.1371/journal.pone.0246989  0.01
2021 Baldwin I, Shafer RL, Hossain WA, Gunewardena S, Veatch OJ, Mosconi MW, Butler MG. Genomic, Clinical, and Behavioral Characterization of 15q11.2 BP1-BP2 Deletion (Burnside-Butler) Syndrome in Five Families. International Journal of Molecular Sciences. 22. PMID 33562221 DOI: 10.3390/ijms22041660  1
2021 De A, Zhou J, Liu P, Huang M, Gunewardena S, Mathur SC, Christenson LK, Sharma M, Zhang Q, Bansal A. Forkhead box F1 induces columnar phenotype and epithelial-to-mesenchymal transition in esophageal squamous cells to initiate Barrett's like metaplasia. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 33495575 DOI: 10.1038/s41374-021-00534-4  1
2020 Wang Y, Gunewardena S, Li F, Matye DJ, Chen C, Chao X, Jung T, Zhang Y, Czerwiński M, Ni HM, Ding WX, Li T. An FGF15/19-TFEB regulatory loop controls hepatic cholesterol and bile acid homeostasis. Nature Communications. 11: 3612. PMID 32681035 DOI: 10.1038/s41467-020-17363-6  1
2020 Saha B, Ganguly A, Home P, Bhattacharya B, Ray S, Ghosh A, Rumi MAK, Marsh C, French VA, Gunewardena S, Paul S. TEAD4 ensures postimplantation development by promoting trophoblast self-renewal: An implication in early human pregnancy loss. Proceedings of the National Academy of Sciences of the United States of America. PMID 32669432 DOI: 10.1073/Pnas.2002449117  1
2020 Wu H, Reizel T, Wang YJ, Lapiro JL, Kren BT, Schug J, Rao S, Morgan A, Herman A, Shekels LL, Rassette MS, Lane AN, Cassel T, Fan TWM, Manivel JC, ... Gunewardena S, et al. A negative reciprocal regulatory axis between cyclin D1 and HNF4α modulates cell cycle progression and metabolism in the liver. Proceedings of the National Academy of Sciences of the United States of America. PMID 32631996 DOI: 10.1073/Pnas.2002898117  1
2020 Bhattacharya B, Home P, Ganguly A, Ray S, Ghosh A, Islam MR, French V, Marsh C, Gunewardena S, Okae H, Arima T, Paul S. Atypical protein kinase C iota (PKCλ/ι) ensures mammalian development by establishing the maternal-fetal exchange interface. Proceedings of the National Academy of Sciences of the United States of America. PMID 32513715 DOI: 10.1073/Pnas.1920201117  1
2020 Welleford AS, Quintero JE, Seblani NE, Blalock E, Gunewardena S, Shapiro SM, Riordan SM, Huettl P, Guduru Z, Stanford JA, van Horne CG, Gerhardt GA. RNA Sequencing of Human Peripheral Nerve in Response to Injury: Distinctive Analysis of the Nerve Repair Pathways. Cell Transplantation. 29: 963689720926157. PMID 32425114 DOI: 10.1177/0963689720926157  0.12
2020 Liu J, Gunewardena S, Yue Cui J, Klaassen CD, Chorley BN, Corton JC. Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice. Toxicology. 152409. PMID 32068019 DOI: 10.1016/J.Tox.2020.152409  1
2020 Bhushan B, Gunewardena S, Edwards G, Apte U. Comparison of liver regeneration after partial hepatectomy and acetaminophen-induced acute liver failure: A global picture based on transcriptome analysis. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111186. PMID 32045647 DOI: 10.1016/J.Fct.2020.111186  1
2020 Sayed A, Choudhury S, Subramaniam D, Gunewardena S, Ponnurangam S, Dandawate P, Umar S, Jensen R, Thomas S, Anant S. RNA Binding Protein RBM3 Modulates Novel LncRNAs to Increase Tumor Progression in Colon Cancer Cells The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.07588  1
2019 Dandawate P, Ghosh C, Palaniyandi K, Paul S, Rawal S, Pradhan R, Ali Sayed AA, Choudhury S, Standing D, Subramaniam D, Padhye S, Gunewardena S, Thomas SM, Neil MO, Tawfik O, et al. The Histone Demethylase KDM3A, Increased in Human Pancreatic Tumors, Regulates Expression of DCLK1 in and Promotes Tumorigenesis in Mice. Gastroenterology. PMID 31442435 DOI: 10.1053/J.Gastro.2019.08.018  1
2019 Brachova P, Alvarez NS, Hong X, Gunewardena S, Vincent KA, Latham KE, Christenson LK. Inosine RNA modifications are enriched at the codon wobble position in mouse oocytes and eggs. Biology of Reproduction. PMID 31346607 DOI: 10.1093/Biolre/Ioz130  1
2019 Chinnappan M, Gunewardena S, Chalise P, Dhillon NK. Analysis of lncRNA-miRNA-mRNA Interactions in Hyper-proliferative Human Pulmonary Arterial Smooth Muscle Cells. Scientific Reports. 9: 10533. PMID 31324852 DOI: 10.1038/s41598-019-46981-4  1
2019 New J, Subramaniam D, Ramalingam S, Enders J, Sayed AAA, Ponnurangam S, Standing D, Ramamoorthy P, O'Neil M, Dixon DA, Saha S, Umar S, Gunewardena S, Jensen RA, Thomas SM, et al. Pleotropic role of RNA binding protein CELF2 in autophagy induction. Molecular Carcinogenesis. PMID 31020708 DOI: 10.1002/Mc.23023  1
2019 Ghosh C, Paul S, Dandawate P, Gunewardena SS, Subramaniam D, West C, Anant S, Dhar A. Super-enhancers: novel target for pancreatic ductal adenocarcinoma. Oncotarget. 10: 1554-1571. PMID 30899425 DOI: 10.18632/oncotarget.26704  1
2019 Maity G, Ghosh A, Gupta VG, Haque I, Sarkar S, Das A, Dhar K, Bhavanasi S, Gunewardena S, Von Hoff DD, Mallik S, Kambhampati S, Banerjee SK, Banerjee S. Cyr61/CCN1 regulates dCK and CTGF and Causes Gemcitabine Resistant Phenotype in Pancreatic Ductal Adenocarcinoma. Molecular Cancer Therapeutics. PMID 30787177 DOI: 10.1158/1535-7163.Mct-18-0899  1
2019 Ramamoorthy P, Thomas SM, Kaushik G, Subramaniam D, Chastain KM, Dhar A, Tawfik O, Kasi A, Sun W, Ramalingam S, Gunewardena S, Umar S, Mammen JMV, Padhye SB, Weir SJ, et al. Metastatic Tumor-In-A-Dish, A Novel Multi-Cellular Organoid to Study Lung Colonization and Predict Therapeutic Response. Cancer Research. PMID 30674533 DOI: 10.1158/0008-5472.Can-18-2602  1
2019 Ghosh C, Palaniyandi K, Paul S, Dandawate P, Rawal S, Subramaniam D, Padhye S, Gunewardena S, Thomas S, O'Neil M, Jensen R, Welch D, Milisky S, Weir S, Iwakuma T, et al. Abstract 4398: KDM3A and DCLK1 interactions promote stemness and tumorigenesis in PDAC Cancer Research. DOI: 10.1158/1538-7445.Sabcs18-4398  1
2018 Huck I, Gunewardena S, Espanol-Suner R, Willenbring H, Apte U. Hepatocyte Nuclear Factor 4 alpha (HNF4α) Activation is Essential for Termination of Liver Regeneration. Hepatology (Baltimore, Md.). PMID 30520062 DOI: 10.1002/Hep.30405  1
2018 Woo I, Christenson LK, Gunewardena S, Ingles SA, Thomas S, Ahmady A, Chung K, Bendikson K, Paulson R, McGinnis LK. Micro-RNAs involved in cellular proliferation have altered expression profiles in granulosa of young women with diminished ovarian reserve. Journal of Assisted Reproduction and Genetics. PMID 29987422 DOI: 10.1007/S10815-018-1239-9  1
2018 Shew M, Warnecke A, Lenarz T, Schmitt H, Gunewardena S, Staecker H. Feasibility of microRNA profiling in human inner ear perilymph. Neuroreport. 29: 894-901. PMID 29781875 DOI: 10.1097/WNR.0000000000001049  0.01
2018 Sharma H, Chinnappan M, Agarwal S, Dalvi P, Gunewardena S, O'Brien-Ladner A, Dhillon NK. Macrophage-derived extracellular vesicles mediates smooth muscle hyperplasia: role of altered miRNA cargo in response to HIV-infection and substance abuse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201701558R. PMID 29672222 DOI: 10.1096/fj.201701558R  1
2018 Borude P, Bhushan B, Gunewardena S, Akakpo J, Jaeschke H, Apte U. Pleiotropic Role of p53 in Injury and Liver Regeneration after Acetaminophen Overdose. The American Journal of Pathology. PMID 29654721 DOI: 10.1016/j.ajpath.2018.03.006  1
2018 Jones JW, Usman S, New J, Holcomb A, Gunewardena S, Tawfik O, Hoover L, Bruegger D, Thomas SM. Differential Gene Expression and Pathway Analysis in Juvenile Nasopharyngeal Angiofibroma Using RNA Sequencing. Otolaryngology--Head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery. 194599818769879. PMID 29634432 DOI: 10.1177/0194599818769879  1
2018 Freitas N, Lukash T, Gunewardena S, Chappell B, Slagle BL, Gudima SO. Relative Abundance of Integrant-Derived Viral RNAs in Infected Tissues Harvested from Chronic Hepatitis B Virus Carriers. Journal of Virology. 92. PMID 29491161 DOI: 10.1128/JVI.02221-17  0.04
2018 Kumar D, Yalamanchali S, New J, Parsel S, New N, Holcomb A, Gunewardena S, Tawfik O, Lominska C, Kimler BF, Anant S, Kakarala K, Tsue T, Shnayder Y, Sykes K, et al. Development and Characterization of an In Vitro Model for Radiation-Induced Fibrosis. Radiation Research. PMID 29351058 DOI: 10.1667/RR14926.1  1
2018 De A, Zhou J, Sharma M, Gunewardena S, Christenson L, Bansal A. Sa1655 - Forkhead Box F1 (Foxf1) can not only Induce a Barrett's Esophagus Like Metaplastic Change but also Induce Malignant Behavior in Normal Esophageal Cells Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)31479-3  1
2018 Sayed AAA, Subramaniam D, Gunewardena S, Ponnurangam S, Choudhury S, Enders J, Jensen RA, Thomas SM, Umar S, Anant S. 520 - RBM3 Increases Tumor Progression by Increasing Stemness and Metastasis in Colon Cancer Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)30819-9  1
2017 Bhattacherjee A, Winter MK, Eggimann LS, Mu Y, Gunewardena S, Liao Z, Christianson JA, Smith PG. Motor, Somatosensory, Viscerosensory and Metabolic Impairments in a Heterozygous Female Rat Model of Rett Syndrome. International Journal of Molecular Sciences. 19. PMID 29286317 DOI: 10.3390/ijms19010097  1
2017 Bhattacherjee A, Mu Y, Winter MK, Knapp JR, Eggimann LS, Gunewardena SS, Kobayashi K, Kato S, Krizsan-Agbas D, Smith PG. Neuronal cytoskeletal gene dysregulation and mechanical hypersensitivity in a rat model of Rett syndrome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28760966 DOI: 10.1073/pnas.1618210114  1
2017 Pohler KG, Green JA, Moley LA, Gunewardena S, Hung WT, Payton RR, Hong X, Christenson LK, Geary TW, Smith MF. Circulating microRNA as candidates for early embryonic viability in cattle. Molecular Reproduction and Development. PMID 28643872 DOI: 10.1002/Mrd.22856  1
2017 Garimella R, Tadikonda P, Tawfik O, Gunewardena S, Rowe P, Van Veldhuizen P. Vitamin D Impacts the Expression of Runx2 Target Genes and Modulates Inflammation, Oxidative Stress and Membrane Vesicle Biogenesis Gene Networks in 143B Osteosarcoma Cells. International Journal of Molecular Sciences. 18. PMID 28300755 DOI: 10.3390/ijms18030642  1
2017 Home P, Kumar RP, Ganguly A, Saha B, Milano-Foster J, Bhattacharya B, Ray S, Gunewardena S, Paul A, Camper SA, Fields PE, Paul S. Genetic redundancy of GATA factors in extraembryonic trophoblast lineage ensures progression of both pre and postimplantation mammalian development. Development (Cambridge, England). PMID 28232602 DOI: 10.1242/Dev.145318  1
2017 Nwachokor J, Gunewardena S, De A, Sharma M, Sharma P, Christenson L, Bansal A. Cellular Pathways are Differentially Activated in Black Versus White Patients with Gastroesophageal Reflux Disease: Implications for Race-Based Disease Pathogenesis Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)32336-3  1
2017 Nwachokor J, Gunewardena S, Sharma M, De A, Sharma P, Christenson L, Bansal A. Use of Molecular Analysis to Inform Clinical Management of Black Patients with Barrett's Esophagus Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)31726-2  1
2016 Wilson C, Qiu L, Hong Y, Karnik T, Tadros G, Mau B, Ma T, Mu Y, New J, Louie RJ, Gunewardena S, Godwin AK, Tawfik OW, Chien J, Roby KF, et al. The histone demethylase KDM4B regulates peritoneal seeding of ovarian cancer. Oncogene. PMID 27869162 DOI: 10.1038/onc.2016.412  1
2016 Navakanitworakul R, Hung WT, Gunewardena S, Davis JS, Chotigeat W, Christenson LK. Characterization and Small RNA Content of Extracellular Vesicles in Follicular Fluid of Developing Bovine Antral Follicles. Scientific Reports. 6: 25486. PMID 27158133 DOI: 10.1038/Srep25486  1
2016 Beggs KM, McGreal SR, McCarthy A, Gunewardena S, Lampe JN, Lau C, Apte U. The role of hepatocyte nuclear factor 4-alpha in perfluorooctanoic acid- and perfluorooctanesulfonic acid-induced hepatocellular dysfunction. Toxicology and Applied Pharmacology. PMID 27153767 DOI: 10.1016/J.Taap.2016.05.001  1
2016 Sun L, Beggs K, Borude P, Edwards G, Bhushan B, Walesky C, Roy N, Manley MW, Gunewardena S, O'Neil M, Li H, Apte U. Bile Acids Promote Diethylnitrosamine-induced Hepatocellular Carcinoma via Increased Inflammatory Signaling. American Journal of Physiology. Gastrointestinal and Liver Physiology. ajpgi.00027.2015. PMID 27151938 DOI: 10.1152/Ajpgi.00027.2015  1
2015 Gunewardena SS, Yoo B, Peng L, Lu H, Zhong X, Klaassen CD, Cui JY. Deciphering the Developmental Dynamics of the Mouse Liver Transcriptome. Plos One. 10: e0141220. PMID 26496202 DOI: 10.1371/Journal.Pone.0141220  1
2015 Sharma N, Nanta R, Sharma J, Gunewardena S, Singh KP, Shankar S, Srivastava RK. PI3K/AKT/mTOR and sonic hedgehog pathways cooperate together to inhibit human pancreatic cancer stem cell characteristics and tumor growth. Oncotarget. PMID 26451606 DOI: 10.18632/oncotarget.5055  1
2015 Gunewardena S, Walesky C, Apte U. Global Gene Expression Changes in Liver Following Hepatocyte Nuclear Factor 4 alpha deletion in Adult Mice. Genomics Data. 5: 126-128. PMID 26120557 DOI: 10.1016/J.Gdata.2015.05.037  1
2015 Butler MG, Wang K, Marshall JD, Naggert JK, Rethmeyer JA, Gunewardena SS, Manzardo AM. Coding and noncoding expression patterns associated with rare obesity-related disorders: Prader-Willi and Alström syndromes. Advances in Genomics and Genetics. 2015: 53-75. PMID 25705109 DOI: 10.2147/AGG.S74598  1
2015 Chavan H, Li F, Tessman R, Mickey K, Dorko K, Schmitt T, Kumer S, Gunewardena S, Gaikwad N, Krishnamurthy P. Functional coupling of ATP-binding cassette transporter Abcb6 to cytochrome P450 expression and activity in liver. The Journal of Biological Chemistry. 290: 7871-86. PMID 25623066 DOI: 10.1074/jbc.M114.605386  1
2015 Wang H, Graham I, Hastings R, Gunewardena S, Brinkmeier ML, Conn PM, Camper SA, Kumar TR. Gonadotrope-specific deletion of Dicer results in severely suppressed gonadotropins and fertility defects. The Journal of Biological Chemistry. 290: 2699-714. PMID 25525274 DOI: 10.1074/jbc.M114.621565  1
2015 Kumaraswamy E, Wendt KL, Augustine LA, Stecklein SR, Sibala EC, Li D, Gunewardena S, Jensen RA. BRCA1 regulation of epidermal growth factor receptor (EGFR) expression in human breast cancer cells involves microRNA-146a and is critical for its tumor suppressor function. Oncogene. 34: 4333-46. PMID 25417703 DOI: 10.1038/Onc.2014.363  1
2014 Bansal A, Hong X, Lee IH, Krishnadath KK, Mathur SC, Gunewardena S, Rastogi A, Sharma P, Christenson LK. MicroRNA Expression can be a Promising Strategy for the Detection of Barrett's Esophagus: A Pilot Study. Clinical and Translational Gastroenterology. 5: e65. PMID 25502391 DOI: 10.1038/Ctg.2014.17  1
2014 Hendry WJ, Hariri HY, Alwis ID, Gunewardena SS, Hendry IR. Altered gene expression patterns during the initiation and promotion stages of neonatally diethylstilbestrol-induced hyperplasia/dysplasia/neoplasia in the hamster uterus. Reproductive Toxicology (Elmsford, N.Y.). 50: 68-86. PMID 25242112 DOI: 10.1016/j.reprotox.2014.09.002  0.01
2014 Manzardo AM, Gunewardena S, Wang K, Butler MG. Exon microarray analysis of human dorsolateral prefrontal cortex in alcoholism. Alcoholism, Clinical and Experimental Research. 38: 1594-601. PMID 24890784 DOI: 10.1111/acer.12429  1
2014 Paul A, Gunewardena S, Stecklein SR, Saha B, Parelkar N, Danley M, Rajendran G, Home P, Ray S, Jokar I, Vielhauer GA, Jensen RA, Tawfik O, Paul S. PKCλ/ι signaling promotes triple-negative breast cancer growth and metastasis. Cell Death and Differentiation. 21: 1469-81. PMID 24786829 DOI: 10.1038/Cdd.2014.62  1
2014 Fiskus W, Saba N, Shen M, Ghias M, Liu J, Gupta SD, Chauhan L, Rao R, Gunewardena S, Schorno K, Austin CP, Maddocks K, Byrd J, Melnick A, Huang P, et al. Auranofin induces lethal oxidative and endoplasmic reticulum stress and exerts potent preclinical activity against chronic lymphocytic leukemia. Cancer Research. 74: 2520-32. PMID 24599128 DOI: 10.1158/0008-5472.Can-13-2033  1
2013 Peng L, Cui JY, Yoo B, Gunewardena SS, Lu H, Klaassen CD, Zhong XB. RNA-sequencing quantification of hepatic ontogeny of phase-I enzymes in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 2175-86. PMID 24080161 DOI: 10.1124/Dmd.113.054635  1
2013 Surgucheva I, Gunewardena S, Rao HS, Surguchov A. Cell-specific post-transcriptional regulation of γ-synuclein gene by micro-RNAs. Plos One. 8: e73786. PMID 24040069 DOI: 10.1371/journal.pone.0073786  0.08
2013 Manzardo AM, Gunewardena S, Butler MG. Over-expression of the miRNA cluster at chromosome 14q32 in the alcoholic brain correlates with suppression of predicted target mRNA required for oligodendrocyte proliferation. Gene. 526: 356-63. PMID 23747354 DOI: 10.1016/j.gene.2013.05.052  1
2013 Christenson LK, Gunewardena S, Hong X, Spitschak M, Baufeld A, Vanselow J. Research resource: preovulatory LH surge effects on follicular theca and granulosa transcriptomes. Molecular Endocrinology (Baltimore, Md.). 27: 1153-71. PMID 23716604 DOI: 10.1210/Me.2013-1093  1
2013 Lu H, Gunewardena S, Cui JY, Yoo B, Zhong XB, Klaassen CD. RNA-sequencing quantification of hepatic ontogeny and tissue distribution of mRNAs of phase II enzymes in mice. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 41: 844-57. PMID 23382457 DOI: 10.1124/Dmd.112.050211  1
2013 Walesky C, Edwards G, Borude P, Gunewardena S, O'Neil M, Yoo B, Apte U. Hepatocyte nuclear factor 4 alpha deletion promotes diethylnitrosamine-induced hepatocellular carcinoma in rodents. Hepatology (Baltimore, Md.). 57: 2480-90. PMID 23315968 DOI: 10.1002/Hep.26251  1
2013 Varghese BV, Koohestani F, McWilliams M, Colvin A, Gunewardena S, Kinsey WH, Nowak RA, Nothnick WB, Chennathukuzhi VM. Loss of the repressor REST in uterine fibroids promotes aberrant G protein-coupled receptor 10 expression and activates mammalian target of rapamycin pathway. Proceedings of the National Academy of Sciences of the United States of America. 110: 2187-92. PMID 23284171 DOI: 10.1073/Pnas.1215759110  0.01
2013 Walesky C, Gunewardena S, Terwilliger EF, Edwards G, Borude P, Apte U. Hepatocyte-specific deletion of hepatocyte nuclear factor-4α in adult mice results in increased hepatocyte proliferation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 304: G26-37. PMID 23104559 DOI: 10.1152/Ajpgi.00064.2012  1
2013 Sethi G, Pathak H, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. Abstract A06: Integration of synthetic lethality and genomic data to identify significant molecular vulnerabilities in ovarian cancer Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Pms-A06  1
2012 Sethi G, Pathak HB, Zhang H, Zhou Y, Einarson MB, Vathipadiekal V, Gunewardena S, Birrer MJ, Godwin AK. An RNA interference lethality screen of the human druggable genome to identify molecular vulnerabilities in epithelial ovarian cancer. Plos One. 7: e47086. PMID 23056589 DOI: 10.1371/Journal.Pone.0047086  1
2012 Lu H, Cui JY, Gunewardena S, Yoo B, Zhong XB, Klaassen CD. Hepatic ontogeny and tissue distribution of mRNAs of epigenetic modifiers in mice using RNA-sequencing. Epigenetics. 7: 914-29. PMID 22772165 DOI: 10.4161/Epi.21113  1
2012 Home P, Saha B, Ray S, Dutta D, Gunewardena S, Yoo B, Pal A, Vivian JL, Larson M, Petroff M, Gallagher PG, Schulz VP, White KL, Golos TG, Behr B, et al. Altered subcellular localization of transcription factor TEAD4 regulates first mammalian cell lineage commitment Proceedings of the National Academy of Sciences of the United States of America. 109: 7362-7367. PMID 22529382 DOI: 10.1073/Pnas.1201595109  1
2012 Cui JY, Gunewardena SS, Yoo B, Liu J, Renaud HJ, Lu H, Zhong XB, Klaassen CD. RNA-Seq reveals different mRNA abundance of transporters and their alternative transcript isoforms during liver development. Toxicological Sciences : An Official Journal of the Society of Toxicology. 127: 592-608. PMID 22454430 DOI: 10.1093/Toxsci/Kfs107  1
2012 Peng L, Yoo B, Gunewardena SS, Lu H, Klaassen CD, Zhong XB. RNA sequencing reveals dynamic changes of mRNA abundance of cytochromes P450 and their alternative transcripts during mouse liver development. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 40: 1198-209. PMID 22434873 DOI: 10.1124/Dmd.112.045088  1
2012 Septer S, Edwards G, Gunewardena S, Wolfe A, Li H, Daniel J, Apte U. Yes-associated protein is involved in proliferation and differentiation during postnatal liver development. American Journal of Physiology. Gastrointestinal and Liver Physiology. 302: G493-503. PMID 22194415 DOI: 10.1152/Ajpgi.00056.2011  1
2010 Cui JY, Gunewardena SS, Rockwell CE, Klaassen CD. ChIPing the cistrome of PXR in mouse liver. Nucleic Acids Research. 38: 7943-63. PMID 20693526 DOI: 10.1093/Nar/Gkq654  1
2008 Gunewardena S, Zhang Z. A hybrid model for robust detection of transcription factor binding sites. Bioinformatics (Oxford, England). 24: 484-91. PMID 18184687 DOI: 10.1093/Bioinformatics/Btm629  1
2006 Gunewardena S, Zhang Z. Accounting for structural properties and nucleotide co-variations in the quantitative prediction of binding affinities of protein-DNA interactions. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 379-90. PMID 17094254  1
2006 Gunewardena S, Jeavons P, Zhang Z. Enhancing the prediction of transcription factor binding sites by incorporating structural properties and nucleotide covariations. Journal of Computational Biology : a Journal of Computational Molecular Cell Biology. 13: 929-45. PMID 16761919 DOI: 10.1089/Cmb.2006.13.929  1
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