Pawel Lorkiewicz - Publications

University of Louisville, Louisville 
stable isotope resolved metabolomics, mass spectrometry, tobacco products, metabolomics, method development

34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Jin L, Lorkiewicz P, Malovichko MV, Bhatnagar A, Srivastava S, Conklin DJ. Acetaldehyde Induces an Endothelium-Dependent Relaxation of Superior Mesenteric Artery: Potential Role in Postprandial Hyperemia. Frontiers in Physiology. 10: 1315. PMID 31695624 DOI: 10.3389/fphys.2019.01315  0.6
2019 Donde H, Ghare S, Joshi-Barve S, Zhang J, Vadhanam MV, Gobejishvili L, Lorkiewicz P, Srivastava S, McClain CJ, Barve S. Tributyrin inhibits ethanol-induced epigenetic repression of CPT-1A and attenuates hepatic steatosis and injury. Cellular and Molecular Gastroenterology and Hepatology. PMID 31654770 DOI: 10.1016/j.jcmgh.2019.10.005  0.52
2019 Lombardi AA, Gibb AA, Arif E, Kolmetzky DW, Tomar D, Luongo TS, Jadiya P, Murray EK, Lorkiewicz PK, Hajnóczky G, Murphy E, Arany ZP, Kelly DP, Margulies KB, Hill BG, et al. Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation. Nature Communications. 10: 4509. PMID 31586055 DOI: 10.1038/s41467-019-12103-x  0.36
2019 Lorkiewicz PK, Gibb AA, Rood BR, He L, Zheng Y, Clem BF, Zhang X, Hill BG. Integration of flux measurements and pharmacological controls to optimize stable isotope-resolved metabolomics workflows and interpretation. Scientific Reports. 9: 13705. PMID 31548575 DOI: 10.1038/s41598-019-50183-3  0.36
2019 Nystoriak MA, Kilfoil PJ, Lorkiewicz PK, Ramesh B, Kuehl PJ, McDonald J, Bhatnagar A, Conklin DJ. Comparative effects of parent and heated cinnamaldehyde on the function of human iPSC-derived cardiac myocytes. Toxicology in Vitro : An International Journal Published in Association With Bibra. 104648. PMID 31518667 DOI: 10.1016/j.tiv.2019.104648  0.6
2019 Keith RJ, Fetterman JL, Orimoloye OA, Dardari Z, Lorkiewicz P, Hamburg NM, DeFilippis AP, Blaha MJ, Bhatnagar A. Characterization of Volatile Organic Compound (VOC) metabolites in Cigarette smokers, Electronic Nicotine Device Users, Dual Users and Non- users of tobacco. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 30759242 DOI: 10.1093/ntr/ntz021  0.6
2018 Conklin DJ, Ogunwale MA, Chen Y, Theis WS, Nantz MH, Fu XA, Chen LC, Riggs DW, Lorkiewicz P, Bhatnagar A, Srivastava S. Electronic cigarette-generated aldehydes: The contribution of e-liquid components to their formation and the use of urinary aldehyde metabolites as biomarkers of exposure. Aerosol Science and Technology : the Journal of the American Association For Aerosol Research. 52: 1219-1232. PMID 31456604 DOI: 10.1080/02786826.2018.1500013  0.6
2018 Yeager R, Riggs DW, DeJarnett N, Tollerud DJ, Wilson J, Conklin DJ, O'Toole TE, McCracken J, Lorkiewicz P, Xie Z, Zafar N, Krishnasamy SS, Srivastava S, Finch J, Keith RJ, et al. Association Between Residential Greenness and Cardiovascular Disease Risk. Journal of the American Heart Association. 7: e009117. PMID 30561265 DOI: 10.1161/JAHA.118.009117  0.6
2018 Mehra P, Guo Y, Nong Y, Lorkiewicz P, Nasr M, Li Q, Muthusamy S, Bradley JA, Bhatnagar A, Wysoczynski M, Bolli R, Hill BG. Cardiac mesenchymal cells from diabetic mice are ineffective for cell therapy-mediated myocardial repair. Basic Research in Cardiology. 113: 46. PMID 30353243 DOI: 10.1007/s00395-018-0703-0  0.6
2018 Xie Z, Lorkiewicz P, Riggs DW, Bhatnagar A, Srivastava S. Comprehensive, robust, and sensitive UPLC-MS/MS analysis of free biogenic monoamines and their metabolites in urine. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1099: 83-91. PMID 30248561 DOI: 10.1016/j.jchromb.2018.09.012  0.6
2018 He L, Prodhan MAI, Yuan F, Yin X, Lorkiewicz PK, Wei X, Feng W, McClain C, Zhang X. Simultaneous quantification of straight-chain and branched-chain short chain fatty acids by gas chromatography mass spectrometry. Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences. 1092: 359-367. PMID 29936372 DOI: 10.1016/j.jchromb.2018.06.028  0.36
2018 Lorkiewicz P, Riggs DW, Keith RJ, Conklin DJ, Xie Z, Sutaria S, Lynch B, Srivastava S, Bhatnagar A. Comparison of Urinary Biomarkers of Exposure in Humans Using Electronic Cigarettes, Combustible Cigarettes, and Smokeless Tobacco. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 29868926 DOI: 10.1093/ntr/nty089  0.6
2018 Keith RJ, Fetterman JL, Riggs DW, O'Toole T, Nystoriak JL, Holbrook M, Lorkiewicz P, Bhatnagar A, DeFilippis AP, Hamburg NM. Protocol to assess the impact of tobacco-induced volatile organic compounds on cardiovascular risk in a cross- sectional cohort: Cardiovascular Injury due to Tobacco Use study. Bmj Open. 8: e019850. PMID 29602846 DOI: 10.1136/bmjopen-2017-019850  0.6
2017 Malovichko MV, Zeller I, Krivokhizhina TV, Xie Z, Lorkiewicz P, Agarwal A, Wickramasinghe N, Sithu SD, Shah J, O'Toole T, Rai SN, Bhatnagar A, Conklin DJ, Srivastava S. Systemic Toxicity of Smokeless Tobacco Products in Mice. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 30085294 DOI: 10.1093/ntr/ntx230  0.6
2017 Gibb AA, Lorkiewicz PK, Zheng YT, Zhang X, Bhatnagar A, Jones SP, Hill BG. Correction: Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes. The Biochemical Journal. 474: 4271-4272. PMID 29242383 DOI: 10.1042/BCJ20170474_COR  0.6
2017 Keith RJ, Riggs DW, Conklin DJ, Lorkiewicz P, Srivastava S, Bhatnagar A, DeFilippis AP. Nicotine Metabolism in Adults with Type 2 Diabetes. Nicotine & Tobacco Research : Official Journal of the Society For Research On Nicotine and Tobacco. PMID 29059414 DOI: 10.1093/ntr/ntx214  0.6
2017 Gibb AA, Lorkiewicz PK, Zheng YT, Zhang X, Bhatnagar A, Jones SP, Hill BG. Integration of flux measurements to resolve changes in anabolic and catabolic metabolism in cardiac myocytes. The Biochemical Journal. PMID 28706006 DOI: 10.1042/BCJ20170474  0.6
2017 Wei X, Shi B, Koo I, Yin X, Lorkiewicz P, Suhail H, Rattan R, Giri S, McClain CJ, Zhang X. Analysis of stable isotope assisted metabolomics data acquired by GC-MS. Analytica Chimica Acta. 980: 25-32. PMID 28622800 DOI: 10.1016/j.aca.2017.05.002  0.36
2017 Schick SF, Blount BC, Jacob P, Saliba NA, Bernert JT, El Hellani A, Jatlow P, Pappas RS, Wang L, Foulds J, Ghosh A, Hecht SS, Gomez JC, Martin JR, Mesaros C, ... ... Lorkiewicz PK, et al. Biomarkers of Exposure to New and Emerging Tobacco and Nicotine Delivery Products. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00343.2016. PMID 28522563 DOI: 10.1152/ajplung.00343.2016  0.6
2017 Conklin DJ, Malovichko MV, Zeller I, Das TP, Krivokhizhina TV, Lynch BH, Lorkiewicz P, Agarwal A, Wickramasinghe N, Haberzettl P, Sithu SD, Shah J, O'Toole TE, Rai SN, Bhatnagar A, et al. Biomarkers of Chronic Acrolein Inhalation Exposure in Mice: Implications for Tobacco Product-Induced Toxicity. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28482051 DOI: 10.1093/toxsci/kfx095  0.6
2016 Salabei JK, Lorkiewicz PK, Mehra P, Gibb AA, Haberzettl P, Hong KU, Wei X, Zhang X, Li Q, Wysoczynski M, Bolli R, Bhatnagar A, Hill BG. Type 2 Diabetes Dysregulates Glucose Metabolism in Cardiac Progenitor Cells. The Journal of Biological Chemistry. PMID 27151219 DOI: 10.1074/jbc.M116.722496  0.6
2016 Koo I, Kim S, Shi B, Lorkiewicz P, Song M, McClain C, Zhang X. EIder: A compound identification tool for gas chromatography mass spectrometry data. Journal of Chromatography. A. PMID 27131963 DOI: 10.1016/j.chroma.2016.04.064  0.36
2015 Salabei JK, Lorkiewicz PK, Holden CR, Li Q, Hong KU, Bolli R, Bhatnagar A, Hill BG. Glutamine Regulates Cardiac Progenitor Cell Metabolism and Proliferation. Stem Cells (Dayton, Ohio). 33: 2613-27. PMID 25917428 DOI: 10.1002/stem.2047  0.6
2015 Lane AN, Arumugam S, Lorkiewicz PK, Higashi RM, Laulhé S, Nantz MH, Moseley HN, Fan TW. Chemoselective detection and discrimination of carbonyl-containing compounds in metabolite mixtures by 1H-detected 15N nuclear magnetic resonance. Magnetic Resonance in Chemistry : Mrc. 53: 337-43. PMID 25616249 DOI: 10.1002/mrc.4199  0.6
2014 Higashi RM, Fan TW, Lorkiewicz PK, Moseley HN, Lane AN. Stable isotope-labeled tracers for metabolic pathway elucidation by GC-MS and FT-MS. Methods in Molecular Biology (Clifton, N.J.). 1198: 147-67. PMID 25270929 DOI: 10.1007/978-1-4939-1258-2_11  0.6
2014 Ren JG, Seth P, Clish CB, Lorkiewicz PK, Higashi RM, Lane AN, Fan TW, Sukhatme VP. Knockdown of malic enzyme 2 suppresses lung tumor growth, induces differentiation and impacts PI3K/AKT signaling. Scientific Reports. 4: 5414. PMID 24957098 DOI: 10.1038/srep05414  0.6
2014 Gori SS, Lorkiewicz P, Ehringer DS, Belshoff AC, Higashi RM, Fan TW, Nantz MH. Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry. Analytical and Bioanalytical Chemistry. 406: 4371-9. PMID 24858467 DOI: 10.1007/s00216-014-7810-z  0.6
2014 Xie H, Hanai J, Ren JG, Kats L, Burgess K, Bhargava P, Signoretti S, Billiard J, Duffy KJ, Grant A, Wang X, Lorkiewicz PK, Schatzman S, Bousamra M, Lane AN, et al. Targeting lactate dehydrogenase--a inhibits tumorigenesis and tumor progression in mouse models of lung cancer and impacts tumor-initiating cells. Cell Metabolism. 19: 795-809. PMID 24726384 DOI: 10.1016/j.cmet.2014.03.003  0.6
2014 Guin S, Pollard C, Ru Y, Ritterson Lew C, Duex JE, Dancik G, Owens C, Spencer A, Knight S, Holemon H, Gupta S, Hansel D, Hellerstein M, Lorkiewicz P, Lane AN, et al. Role in tumor growth of a glycogen debranching enzyme lost in glycogen storage disease. Journal of the National Cancer Institute. 106. PMID 24700805 DOI: 10.1093/jnci/dju062  0.6
2013 Dong C, Yuan T, Wu Y, Wang Y, Fan TW, Miriyala S, Lin Y, Yao J, Shi J, Kang T, Lorkiewicz P, St Clair D, Hung MC, Evers BM, Zhou BP. Loss of FBP1 by Snail-mediated repression provides metabolic advantages in basal-like breast cancer. Cancer Cell. 23: 316-31. PMID 23453623 DOI: 10.1016/j.ccr.2013.01.022  0.6
2012 Lorkiewicz P, Higashi RM, Lane AN, Fan TW. High information throughput analysis of nucleotides and their isotopically enriched isotopologues by direct-infusion FTICR-MS. Metabolomics : Official Journal of the Metabolomic Society. 8: 930-939. PMID 23101002 DOI: 10.1007/s11306-011-0388-y  0.6
2012 Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, Zhang H, Zimmerman LJ, Liebler DC, Slebos RJ, Lorkiewicz PK, Higashi RM, et al. Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells. Cell Metabolism. 15: 110-21. PMID 22225880 DOI: 10.1016/j.cmet.2011.12.009  0.6
2012 Fan TW, Lorkiewicz PK, Sellers K, Moseley HN, Higashi RM, Lane AN. Stable isotope-resolved metabolomics and applications for drug development. Pharmacology & Therapeutics. 133: 366-91. PMID 22212615 DOI: 10.1016/j.pharmthera.2011.12.007  0.6
2009 Lorkiewicz P, Yappert MC. Titania microparticles and nanoparticles as matrixes for in vitro and in situ analysis of small molecules by MALDI-MS. Analytical Chemistry. 81: 6596-603. PMID 20337373 DOI: 10.1021/ac9001113  0.68
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