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Bernard D Santarsiero - Publications

Affiliations: 
University of Illinois at Chicago, Chicago, IL, United States 
Area:
Crystallography, Structural Chemistry, Structural Biology, Drug Discovery
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63 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Hevener KE, Santarsiero BD, Lee H, Jones JA, Boci T, Johnson ME, Mehboob S. Structural characterization of Porphyromonas gingivalis enoyl-ACP reductase II (FabK). Acta Crystallographica. Section F, Structural Biology Communications. 74: 105-112. PMID 29400320 DOI: 10.1107/S2053230X18000262  0.346
2016 Rice AJ, Lei H, Santarsiero BD, Lee H, Johnson ME. Ca-asp bound X-ray structure and inhibition of Bacillus anthracis dihydroorotase (DHOase). Bioorganic & Medicinal Chemistry. PMID 27499369 DOI: 10.1016/J.Bmc.2016.07.055  0.32
2016 Guo B, Onakpa MM, Huang XJ, Santarsiero BD, Chen WL, Zhao M, Zhang XQ, Swanson SM, Burdette JE, Che CT. Di-nor- and 17-nor-pimaranes from Icacina trichantha. Journal of Natural Products. PMID 27340832 DOI: 10.1021/Acs.Jnatprod.6B00289  0.32
2016 Johnson OO, Zhao M, Gunn J, Santarsiero BD, Yin ZQ, Ayoola GA, Coker HA, Che CT. α-Glucosidase Inhibitory Prenylated Anthranols from Harungana madagascariensis. Journal of Natural Products. PMID 26727375 DOI: 10.1055/S-0036-1596491  0.307
2015 Zhao M, Onakpa MM, Santarsiero BD, Chen WL, Szymulanska-Ramamurthy KM, Swanson SM, Burdette JE, Che CT. (9βH)-Pimaranes and Derivatives from the Tuber of Icacina trichantha. Journal of Natural Products. PMID 26523419 DOI: 10.1021/Acs.Jnatprod.5B00688  0.305
2015 Zhao M, Onakpa MM, Santarsiero BD, Huang XJ, Zhang XQ, Chen J, Cheng JJ, Longnecker R, Che CT. Icacinlactone H and Icacintrichantholide from the Tuber of Icacina trichantha. Organic Letters. PMID 26183449 DOI: 10.1021/Acs.Orglett.5B01806  0.318
2015 McClay K, Mehboob S, Yu J, Santarsiero BD, Deng J, Cook JL, Jeong H, Johnson ME, Steffan RJ. Indole trimers with antibacterial activity against Gram-positive organisms produced using combinatorial biocatalysis. Amb Express. 5: 125. PMID 26112315 DOI: 10.1186/S13568-015-0125-4  0.304
2015 Mehboob S, Song J, Hevener KE, Su PC, Boci T, Brubaker L, Truong L, Mistry T, Deng J, Cook JL, Santarsiero BD, Ghosh AK, Johnson ME. Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI). Bioorganic & Medicinal Chemistry Letters. 25: 1292-6. PMID 25677657 DOI: 10.1016/J.Bmcl.2015.01.048  0.323
2014 Nomme J, Li Z, Gipson RM, Wang J, Armijo AL, Le T, Poddar S, Smith T, Santarsiero BD, Nguyen HA, Czernin J, Alexandrova AN, Jung ME, Radu CG, Lavie A. Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability. Journal of Medicinal Chemistry. 57: 9480-94. PMID 25341194 DOI: 10.1021/Jm501124J  0.325
2013 Simmler C, Fronczek FR, Pauli GF, Santarsiero BD. Absolute configuration of naturally occurring glabridin. Acta Crystallographica. Section C, Crystal Structure Communications. 69: 1212-6. PMID 24192160 DOI: 10.1107/S0108270113018842  0.319
2012 Hevener KE, Mehboob S, Boci T, Truong K, Santarsiero BD, Johnson ME. Expression, purification and characterization of enoyl-ACP reductase II, FabK, from Porphyromonas gingivalis. Protein Expression and Purification. 85: 100-8. PMID 22820244 DOI: 10.1016/J.Pep.2012.07.003  0.324
2012 Mehboob S, Hevener KE, Truong K, Boci T, Santarsiero BD, Johnson ME. Structural and enzymatic analyses reveal the binding mode of a novel series of Francisella tularensis enoyl reductase (FabI) inhibitors. Journal of Medicinal Chemistry. 55: 5933-41. PMID 22642319 DOI: 10.1021/Jm300489V  0.348
2011 Tuntland ML, Johnson ME, Fung LW, Santarsiero BD. Structure of N5-carboxyaminoimidazole ribonucleotide synthase (PurK) from Bacillus anthracis. Acta Crystallographica. Section D, Biological Crystallography. 67: 870-4. PMID 21931218 DOI: 10.1107/S0907444911029210  0.31
2010 Mehboob S, Truong K, Santarsiero BD, Johnson ME. Structure of the Francisella tularensis enoyl-acyl carrier protein reductase (FabI) in complex with NAD(+) and triclosan. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1436-40. PMID 21045289 DOI: 10.1107/S1744309110039862  0.344
2010 Mehboob S, Mulhearn DC, Truong K, Johnson ME, Santarsiero BD. Structure of dihydroorotase from Bacillus anthracis at 2.6 Å resolution. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1432-5. PMID 21045288 DOI: 10.1107/S1744309110037085  0.32
2010 Mehboob S, Song Y, Witek M, Long F, Santarsiero BD, Johnson ME, Fung LW. Crystal structure of the nonerythroid alpha-spectrin tetramerization site reveals differences between erythroid and nonerythroid spectrin tetramer formation. The Journal of Biological Chemistry. 285: 14572-84. PMID 20228407 DOI: 10.1074/Jbc.M109.080028  0.306
2009 Hawwa R, Aikens J, Turner RJ, Santarsiero BD, Mesecar AD. Structural basis for thermostability revealed through the identification and characterization of a highly thermostable phosphotriesterase-like lactonase from Geobacillus stearothermophilus. Archives of Biochemistry and Biophysics. 488: 109-20. PMID 19615330 DOI: 10.1016/J.Abb.2009.06.005  0.333
2009 Sershon VC, Santarsiero BD, Mesecar AD. Kinetic and X-ray structural evidence for negative cooperativity in substrate binding to nicotinate mononucleotide adenylyltransferase (NMAT) from Bacillus anthracis. Journal of Molecular Biology. 385: 867-88. PMID 18977360 DOI: 10.1016/J.Jmb.2008.10.037  0.339
2008 Tipparaju SK, Mulhearn DC, Klein GM, Chen Y, Tapadar S, Bishop MH, Yang S, Chen J, Ghassemi M, Santarsiero BD, Cook JL, Johlfs M, Mesecar AD, Johnson ME, Kozikowski AP. Design and synthesis of aryl ether inhibitors of the Bacillus anthracis enoyl-ACP reductase. Chemmedchem. 3: 1250-68. PMID 18663709 DOI: 10.1002/Cmdc.200800047  0.328
2008 Calamini B, Santarsiero BD, Boutin JA, Mesecar AD. Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2. The Biochemical Journal. 413: 81-91. PMID 18254726 DOI: 10.1042/Bj20071373  0.325
2007 May M, Mehboob S, Mulhearn DC, Wang Z, Yu H, Thatcher GR, Santarsiero BD, Johnson ME, Mesecar AD. Structural and functional analysis of two glutamate racemase isozymes from Bacillus anthracis and implications for inhibitor design. Journal of Molecular Biology. 371: 1219-37. PMID 17610893 DOI: 10.1016/J.Jmb.2007.05.093  0.307
2006 Ratia K, Saikatendu KS, Santarsiero BD, Barretto N, Baker SC, Stevens RC, Mesecar AD. Severe acute respiratory syndrome coronavirus papain-like protease: structure of a viral deubiquitinating enzyme. Proceedings of the National Academy of Sciences of the United States of America. 103: 5717-22. PMID 16581910 DOI: 10.1073/Pnas.0510851103  0.592
2006 Zhang HJ, Ma C, Nguyen VH, Nguyen MC, Tan GT, Santarsiero BD, Mesecar AD, Soejarto DD, Pezzuto JM, Fong HH. Miliusanes, a class of cytotoxic agents from Miliusa sinensis. Journal of Medicinal Chemistry. 49: 693-708. PMID 16420055 DOI: 10.1021/Jm0509492  0.316
2005 Larsen S, Ratia K, Santarsiero BD, Mesecar AD. Structural studies of a novel phosphotriesterase capable of degrading soman Acta Crystallographica Section a Foundations of Crystallography. 61: c255-c255. DOI: 10.1107/S0108767305089117  0.317
2003 Su BN, Park EJ, Nikolic D, Santarsiero BD, Mesecar AD, Vigo JS, Graham JG, Cabieses F, van Breemen RB, Fong HH, Farnsworth NR, Pezzuto JM, Kinghorn AD. Activity-guided isolation of novel norwithanolides from depreasubtriflora with potential cancer chemopreventive activity. The Journal of Organic Chemistry. 68: 2350-61. PMID 12636402 DOI: 10.1021/Jo020542U  0.312
2003 Park S, Hayes BL, Marankan F, Mulhearn DC, Wanna L, Mesecar AD, Santarsiero BD, Johnson ME, Venton DL. Regioselective covalent modification of hemoglobin in search of antisickling agents. Journal of Medicinal Chemistry. 46: 936-53. PMID 12620071 DOI: 10.1021/Jm020361K  0.314
2002 Jang DS, Park EJ, Hawthorne ME, Vigo JS, Graham JG, Cabieses F, Santarsiero BD, Mesecar AD, Fong HH, Mehta RG, Pezzuto JM, Kinghorn AD. Constituents of Musa x paradisiaca cultivar with the potential to induce the phase II enzyme, quinone reductase. Journal of Agricultural and Food Chemistry. 50: 6330-4. PMID 12381112 DOI: 10.1021/Jf0206670  0.335
2002 Su BN, Park EJ, Mbwambo ZH, Santarsiero BD, Mesecar AD, Fong HH, Pezzuto JM, Kinghorn AD. New chemical constituents of Euphorbia quinquecostata and absolute configuration assignment by a convenient Mosher ester procedure carried out in NMR tubes. Journal of Natural Products. 65: 1278-82. PMID 12350147 DOI: 10.1021/Np0202475  0.309
2002 Chen SN, Li W, Fabricant DS, Santarsiero BD, Mesecar A, Fitzloff JF, Fong HH, Farnsworth NR. Isolation, structure elucidation, and absolute configuration of 26-deoxyactein from Cimicifuga racemosa and clarification of nomenclature associated with 27-deoxyactein. Journal of Natural Products. 65: 601-5. PMID 11975513 DOI: 10.1021/Np010494T  0.349
2002 Santarsiero BD, Yegian DT, Lee CC, Spraggon G, Gu J, Scheibe D, Uber DC, Cornell EW, Nordmeyer RA, Kolbe WF, Jin J, Jones AL, Jaklevic JM, Schultz PG, Stevens RC. An approach to rapid protein crystallization using nanodroplets Journal of Applied Crystallography. 35: 278-281. DOI: 10.1107/S0021889802001474  0.633
1999 Kobe B, Jennings IG, House CM, Michell BJ, Goodwill KE, Santarsiero BD, Stevens RC, Cotton RG, Kemp BE. Structural basis of autoregulation of phenylalanine hydroxylase. Nature Structural Biology. 6: 442-8. PMID 10331871 DOI: 10.1038/8247  0.601
1998 Romesberg FE, Santarsiero BD, Spiller B, Yin J, Barnes D, Schultz PG, Stevens RC. Structural and kinetic evidence for strain in biological catalysis. Biochemistry. 37: 14404-9. PMID 9772166 DOI: 10.1021/Bi981578C  0.748
1997 Ulrich HD, Mundorff E, Santarsiero BD, Driggers EM, Stevens RC, Schultz PG. The interplay between binding energy and catalysis in the evolution of a catalytic antibody. Nature. 389: 271-5. PMID 9305839 DOI: 10.1038/38470  0.754
1996 Elia GR, Childs RF, Britten JF, Yang DS, Santarsiero BD. Structure and wavelength modification in retinylidene iminium salts Canadian Journal of Chemistry. 74: 591-601. DOI: 10.1139/V96-063  0.327
1996 Santarsiero BD, Hsieh-Wilson LC, Schultz PG, Stevens RC. A sulfide oxidation catalytic antibody Acta Crystallographica Section a Foundations of Crystallography. 52: C223-C224. DOI: 10.1107/S0108767396090435  0.726
1996 Spiller B, Santarsiero BD, Hsieh L, Stevens R. Crystal structure of an amino-acylation catalytic antibody Acta Crystallographica Section a Foundations of Crystallography. 52: C224-C224. DOI: 10.1107/S010876739609040X  0.629
1996 Goodwill KE, Granlund E, Santarsiero BD, Stevens RC. Design of an inverted spindle axis for frozen crystal screening and storage Journal of Applied Crystallography. 29: 738-740. DOI: 10.1107/S0021889896006188  0.572
1996 Stevens RC, Hsieh-Wilson LC, Santarsiero BD, Wedemayer GJ, Spiller B, Wang LH, Barnes D, Ulrich HD, Patten PA, Romesberg FE, Schultz PG. Structural Studies of Catalytic Antibodies Israel Journal of Chemistry. 36: 121-132. DOI: 10.1002/Ijch.199600018  0.719
1994 McPhalen CA, Sielecki AR, Santarsiero BD, James MN. Refined crystal structure of rat parvalbumin, a mammalian alpha-lineage parvalbumin, at 2.0 A resolution. Journal of Molecular Biology. 235: 718-32. PMID 8289291 DOI: 10.1006/Jmbi.1994.1023  0.432
1992 Sturge KC, Hunter AD, McDonald R, Santarsiero BD. One-dimensional materials. 2. Organometallic polymer and linear mono-, bi-, and trimetallic octafluoro-p,p'-biphenylene-bridged complexes of bis(methyldiphenylphosphine)nickel: x-ray crystal structures of Ni(PMePh2)2(4,4'-C12F8H)Br and Ni(PMePh2)2(4,4'-C12F8H)2 Organometallics. 11: 3056-3062. DOI: 10.1021/Om00045A020  0.303
1991 Chukwu R, Hunter AD, Santarsiero BD. Organometallic complexes with electronic bridges. 6. Novel organometallic complexes containing aromatic azines: synthesis and x-ray crystal structure of 4,6-bis[(.eta.5-cyclopentadienyl)dicarbonyliron] 2-(methylthio)pyrimidine Organometallics. 10: 2141-2152. DOI: 10.1021/Om00053A016  0.381
1990 Wang Q, Bennet AJ, Brown RS, Santarsiero B. Distorted amides as models for activated peptide N-C=O units. 2. The synthesis, hydrolytic profile, and molecular structure of 3,4-dihydro-2-oxo-1,4-propanoquinoline Canadian Journal of Chemistry. 68: 1732-1739. DOI: 10.1139/V90-269  0.331
1990 Stille JR, Santarsiero BD, Grubbs RH. Rearrangement of bicyclo[2.2.1]heptane ring systems by titanocene alkylidene complexes to bicyclo[3.2.0]heptane enol ethers. Total synthesis of (.+-.)-.DELTA.9(12)-capnellene The Journal of Organic Chemistry. 55: 843-862. DOI: 10.1021/Jo00290A013  0.311
1988 Anslyn EV, Santarsiero BD, Grubbs RH. Synthesis and structures of bimetallic titanium and chromium carbene complexes of the type Cp2Ti(Cl)O(CH3)CCr(CO)5 Organometallics. 7: 2137-2145. DOI: 10.1021/Om00100A009  0.305
1988 Hillhouse GL, Bulls AR, Santarsiero BD, Bercaw JE. Synthesis and molecular structure of (.eta.5-C5Me5)2Hf(H)(NHMe). Structural evidence for nitrogen-to-hafnium .pi.-donation Organometallics. 7: 1309-1312. DOI: 10.1021/Om00096A012  0.34
1987 Simmons CJ, Hathaway BJ, Santarsiero BD, Clearfield A. The first determination of the energy difference between solid-state conformers by X-ray diffraction. 1. The crystal structure of the pseudo-Jahn–Teller complex (nitrito)bis(2,2′-bipridyl)copper(II) nitrate at 20, 100, 165, and 296 K. 2. The possibility of using X-ray diffraction to characterize adiabatic potential energy surfaces and relative ligand strengths Acta Crystallographica Section a Foundations of Crystallography. 43: C66-C66. DOI: 10.1107/S0108767387083739  0.328
1987 Simmons CJ, Hathaway BJ, Amornjarusiri K, Santarsiero BD, Clearfield A. The first determination of the energy difference between solid-state conformers by x-ray diffraction. 1. The crystal structure of the pseudo-Jahn-Teller complex (nitrito)bis(2,2'-bipyridyl)copper(II) nitrate at 20, 100, 165 and 296 K and of its isostructural zinc(II) analog at 295 K. 2. The possibility of using x-ray diffraction to characterize adiabatic potential energy surfaces and relative ligand strengths Journal of the American Chemical Society. 109: 1947-1958. DOI: 10.1021/Ja00241A009  0.318
1984 Aruffo AA, Santarsiero BD, Schomaker V, Lingafelter EC. Bis(phenylmethanethiolato)(2,3,9,10-tetramethyl-1,4,8,11-tetraaza-1,3,8,10-cyclotetradecatetraene)iron(III) hexafluorophosphate, C28H38FeN4S2+.PF6− Acta Crystallographica Section C Crystal Structure Communications. 40: 1693-1695. DOI: 10.1107/S0108270184009185  0.725
1984 Christie JA, Collins TJ, Krafft TE, Santarsiero BD, Spies GH. Complexation of a tetradentate tetra-anionic ligand to osmium(IV): a step towards the development of multianionic chelating ligands for use in stabilizing oxidizing inorganic complexes Journal of the Chemical Society, Chemical Communications. 198-199. DOI: 10.1039/C39840000198  0.347
1984 Waymouth RM, Santarsiero BD, Grubbs RH. Trigonal-bipyramidal methyl group bridging two zirconocene-ketene centers Journal of the American Chemical Society. 106: 4050-4051. DOI: 10.1021/Ja00326A037  0.314
1984 Miskowski VM, Santarsiero BD, Schaefer WP, Ansok GE, Gray HB. Crystal structure and polarized electronic spectra of a (.mu.-superoxo)dicobalt(III) complex: [((NH3)5Co)2O2](NO3)2Cl3.2H2O Inorganic Chemistry. 23: 172-176. DOI: 10.1021/Ic00170A012  0.301
1984 Coolbaugh TS, Santarsiero BD, Grubbs RH. Synthesis, characterization, and equilibrium studies of Group VIB intramolecular metalloesters: crystal structure of trans-(.eta.5-C5H4)CH2CH2O2CW(CO)2PPh3 Journal of the American Chemical Society. 106: 6310-6318. DOI: 10.1002/Chin.198506288  0.316
1983 Collins TJ, Santarsiero BD, Spies GH. Complexation of secondary amides to chromium(III): the X-ray structure of a molecule with two modes of monodentate organic amide co-ordination Journal of the Chemical Society, Chemical Communications. 681-682. DOI: 10.1039/C39830000681  0.331
1983 El-Hinnawi MA, Aruffo AA, Santarsiero BD, McAlister DR, Schomaker V. Organometallic sulfur complexes. 1. Syntheses, structures, and characterizations of organoiron sulfane complexes (.mu.-Sx)[(.eta.5-C5H5)Fe(CO)2]2 (x = 1-4) Inorganic Chemistry. 22: 1585-1590. DOI: 10.1021/Ic00153A004  0.751
1983 Mayer JM, Wolczanski PT, Santarsiero BD, Olson WA, Bercaw JE. X-ray crystal structure determination of [.eta.5-C5(CH3)5]Ta[P(CH3)3]2H4 and high-field NMR studies of phosphine derivatives of (pentamethylcyclopentadienyl)tantalum(V) hydrides Inorganic Chemistry. 22: 1149-1155. DOI: 10.1021/Ic00150A001  0.322
1983 El-Hinnawi MA, Aruffo AA, Santarsiero BD, Mcalister DR, Schomaker V. ORGANOMETALLIC SULFUR COMPLEXES. 1. SYNTHESES, STRUCTURES, AND CHARACTERIZATIONS OF ORGANOIRON SULFANE COMPLEXES (μ-SX)((η5-C5H5)FE(CO)2)2 (X = 1-4) Cheminform. 14. DOI: 10.1002/Chin.198335308  0.75
1982 Elia AE, Santarsiero BD, Lingafelter EC, Schomaker V. (N-Methylimidazole)(2,3,9,10-tetramethyl-1,4,8,11-tetraazacyclotetradeca-1,3,8,10-tetraene)copper(II) hexafluorophosphate Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 38: 3020-3023. DOI: 10.1107/S0567740882010723  0.543
1981 Aruffo A, Lingafelter EC, Santarsiero BD, Schomaker V. The crystal structures of two cyclopentadienyl iron carbonyl sulfides Acta Crystallographica Section a Foundations of Crystallography. 37: C218-C218. DOI: 10.1107/S0108767381093070  0.594
1981 Santarsiero BD, Esmaili A, Schomaker V, Lingafelter EC. The crystal structure of tetrabutylammonium trisacetylacetonato-cobaltate(II) and -nickelate(II) Acta Crystallographica Section a Foundations of Crystallography. 37: C234-C234. DOI: 10.1107/S0108767381092635  0.583
1979 McCandlish LE, Santarsiero BD, Rose NJ, Lingafelter EC. Acetonitrile(carbonyl)(2,3,9,10-tetramethyl-1,4,8,11-tetraaza-1,3,8,10-cyclotetradecatetraene)iron(II) hexafluorophosphate Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry. 35: 3053-3056. DOI: 10.1107/S056774087901133X  0.511
1979 Valente EJ, Santarsiero BD, Schomaker V. Conformation of dihydropyran rings. Structures of two 3,4-dihydro-2H,5H-pyrano[3,2-c][1]benzopyran-5-ones Journal of Organic Chemistry. 44: 798-802. DOI: 10.1021/Jo01319A029  0.743
1979 Valente EJ, Santarsiero BD, Schomaker V. Conformation Of Dihydropyran Rings. Structures Of Two 3,4-Dihydro-2H,5H-Pyrano(3,2-C)(1)Benzopyran-5-Ones Cheminform. 10. DOI: 10.1002/Chin.197928252  0.743
1979 Valente EJ, Santarsiero BD, Schomaker V. Conformation of dihydropyran rings. Structures of two 3,4-dihydro-2H,5H-pyrano[3,2-c][1]benzopyran-5-ones Journal of Organic Chemistry. 44: 798-802.  0.501
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