Shao-En Ong - Publications

University of Washington, Seattle, Seattle, WA 
Quantitative Proteomics, Signaling

36/68 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Bao XR, Ong SE, Goldberger O, Peng J, Sharma R, Thompson DA, Vafai SB, Cox AG, Marutani E, Ichinose F, Goessling W, Regev A, Carr SA, Clish CB, Mootha VK. Mitochondrial dysfunction remodels one-carbon metabolism in human cells. Elife. 5. PMID 27307216 DOI: 10.7554/eLife.10575  0.6
2015 Golkowski M, Shimizu-Albergine M, Suh HW, Beavo JA, Ong SE. Studying mechanisms of cAMP and cyclic nucleotide phosphodiesterase signaling in Leydig cell function with phosphoproteomics. Cellular Signalling. PMID 26643407 DOI: 10.1016/j.cellsig.2015.11.014  0.6
2015 Daniels CM, Ong SE, Leung AK. The Promise of Proteomics for the Study of ADP-Ribosylation. Molecular Cell. 58: 911-24. PMID 26091340 DOI: 10.1016/j.molcel.2015.06.012  0.6
2014 Yao J, Ong SE, Bajjalieh S. Huntingtin is associated with cytomatrix proteins at the presynaptic terminal. Molecular and Cellular Neurosciences. 63: 96-100. PMID 25461618 DOI: 10.1016/j.mcn.2014.10.003  0.6
2014 Lau HT, Suh HW, Golkowski M, Ong SE. Comparing SILAC- and stable isotope dimethyl-labeling approaches for quantitative proteomics. Journal of Proteome Research. 13: 4164-74. PMID 25077673 DOI: 10.1021/pr500630a  0.6
2014 Lau HT, Lewis KA, Ong SE. Quantifying in vivo, site-specific changes in protein methylation with SILAC. Methods in Molecular Biology (Clifton, N.J.). 1188: 161-75. PMID 25059611 DOI: 10.1007/978-1-4939-1142-4_12  0.6
2014 Daniels CM, Ong SE, Leung AK. Phosphoproteomic approach to characterize protein mono- and poly(ADP-ribosyl)ation sites from cells. Journal of Proteome Research. 13: 3510-22. PMID 24920161 DOI: 10.1021/pr401032q  0.6
2013 Rensvold JW, Ong SE, Jeevananthan A, Carr SA, Mootha VK, Pagliarini DJ. Complementary RNA and protein profiling identifies iron as a key regulator of mitochondrial biogenesis. Cell Reports. 3: 237-45. PMID 23318259 DOI: 10.1016/j.celrep.2012.11.029  0.6
2013 Lee MN, Roy M, Ong SE, Mertins P, Villani AC, Li W, Dotiwala F, Sen J, Doench JG, Orzalli MH, Kramnik I, Knipe DM, Lieberman J, Carr SA, Hacohen N. Identification of regulators of the innate immune response to cytosolic DNA and retroviral infection by an integrative approach. Nature Immunology. 14: 179-85. PMID 23263557 DOI: 10.1038/ni.2509  0.6
2012 Ong SE. The expanding field of SILAC Analytical and Bioanalytical Chemistry. 404: 967-976. PMID 22526667 DOI: 10.1007/s00216-012-5998-3  0.6
2012 Wrann CD, Eguchi J, Bozec A, Xu Z, Mikkelsen T, Gimble J, Nave H, Wagner EF, Ong SE, Rosen ED. FOSL2 promotes leptin gene expression in human and mouse adipocytes. The Journal of Clinical Investigation. 122: 1010-21. PMID 22326952 DOI: 10.1172/JCI58431  0.6
2012 Mertins P, Udeshi ND, Clauser KR, Mani DR, Patel J, Ong SE, Jaffe JD, Carr SA. iTRAQ labeling is superior to mTRAQ for quantitative global proteomics and phosphoproteomics. Molecular & Cellular Proteomics : McP. 11: M111.014423. PMID 22210691 DOI: 10.1074/mcp.M111.014423  0.6
2012 Ong SE, Li X, Schenone M, Schreiber SL, Carr SA. Identifying cellular targets of small-molecule probes and drugs with biochemical enrichment and SILAC. Methods in Molecular Biology (Clifton, N.J.). 803: 129-40. PMID 22065222 DOI: 10.1007/978-1-61779-364-6_9  0.6
2011 Kuai L, Ong SE, Madison JM, Wang X, Duvall JR, Lewis TA, Luce CJ, Conner SD, Pearlman DA, Wood JL, Schreiber SL, Carr SA, Scolnick EM, Haggarty SJ. AAK1 identified as an inhibitor of neuregulin-1/ErbB4-dependent neurotrophic factor signaling using integrative chemical genomics and proteomics. Chemistry & Biology. 18: 891-906. PMID 21802010 DOI: 10.1016/j.chembiol.2011.03.017  0.6
2011 Liu H, Ong SE, Badu-Nkansah K, Schindler J, White FM, Hynes RO. CUB-domain-containing protein 1 (CDCP1) activates Src to promote melanoma metastasis. Proceedings of the National Academy of Sciences of the United States of America. 108: 1379-84. PMID 21220330 DOI: 10.1073/pnas.1017228108  0.6
2010 Reinhardt HC, Hasskamp P, Schmedding I, Morandell S, van Vugt MA, Wang X, Linding R, Ong SE, Weaver D, Carr SA, Yaffe MB. DNA damage activates a spatially distinct late cytoplasmic cell-cycle checkpoint network controlled by MK2-mediated RNA stabilization. Molecular Cell. 40: 34-49. PMID 20932473 DOI: 10.1016/j.molcel.2010.09.018  0.6
2010 van Vugt MA, Gardino AK, Linding R, Ostheimer GJ, Reinhardt HC, Ong SE, Tan CS, Miao H, Keezer SM, Li J, Pawson T, Lewis TA, Carr SA, Smerdon SJ, Brummelkamp TR, et al. A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint. Plos Biology. 8: e1000287. PMID 20126263 DOI: 10.1371/journal.pbio.1000287  0.6
2010 Mortensen P, Gouw JW, Olsen JV, Ong SE, Rigbolt KT, Bunkenborg J, Cox J, Foster LJ, Heck AJ, Blagoev B, Andersen JS, Mann M. MSQuant, an open source platform for mass spectrometry-based quantitative proteomics. Journal of Proteome Research. 9: 393-403. PMID 19888749 DOI: 10.1021/pr900721e  1
2009 Margolin AA, Ong SE, Schenone M, Gould R, Schreiber SL, Carr SA, Golub TR. Empirical Bayes analysis of quantitative proteomics experiments. Plos One. 4: e7454. PMID 19829701 DOI: 10.1371/journal.pone.0007454  0.6
2009 Ong SE, Schenone M, Margolin AA, Li X, Do K, Doud MK, Mani DR, Kuai L, Wang X, Wood JL, Tolliday NJ, Koehler AN, Marcaurelle LA, Golub TR, Gould RJ, et al. Identifying the proteins to which small-molecule probes and drugs bind in cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 4617-22. PMID 19255428 DOI: 10.1073/pnas.0900191106  0.6
2008 Pagliarini DJ, Calvo SE, Chang B, Sheth SA, Vafai SB, Ong SE, Walford GA, Sugiana C, Boneh A, Chen WK, Hill DE, Vidal M, Evans JG, Thorburn DR, Carr SA, et al. A mitochondrial protein compendium elucidates complex I disease biology. Cell. 134: 112-23. PMID 18614015 DOI: 10.1016/j.cell.2008.06.016  0.6
2007 Ong SE, Mann M. Stable isotope labeling by amino acids in cell culture for quantitative proteomics. Methods in Molecular Biology (Clifton, N.J.). 359: 37-52. PMID 17484109 DOI: 10.1007/978-1-59745-255-7_3  1
2007 Lowery DM, Clauser KR, Hjerrild M, Lim D, Alexander J, Kishi K, Ong SE, Gammeltoft S, Carr SA, Yaffe MB. Proteomic screen defines the Polo-box domain interactome and identifies Rock2 as a Plk1 substrate. The Embo Journal. 26: 2262-73. PMID 17446864 DOI: 10.1038/sj.emboj.7601683  0.6
2006 Ong SE, Mann M. Identifying and quantifying sites of protein methylation by heavy methyl SILAC. Current Protocols in Protein Science. Unit 14.9. PMID 18429299 DOI: 10.1002/0471140864.ps1409s46  1
2006 Ong SE, Mann M. A practical recipe for stable isotope labeling by amino acids in cell culture (SILAC). Nature Protocols. 1: 2650-60. PMID 17406521 DOI: 10.1038/nprot.2006.427  1
2005 Ong SE, Mann M. Mass spectrometry-based proteomics turns quantitative. Nature Chemical Biology. 1: 252-62. PMID 16408053 DOI: 10.1038/nchembio736  1
2005 Andersen JS, Lam YW, Leung AK, Ong SE, Lyon CE, Lamond AI, Mann M. Nucleolar proteome dynamics. Nature. 433: 77-83. PMID 15635413 DOI: 10.1038/nature03207  0.6
2004 Ong SE, Mittler G, Mann M. Identifying and quantifying in vivo methylation sites by heavy methyl SILAC. Nature Methods. 1: 119-26. PMID 15782174 DOI: 10.1038/nmeth715  1
2004 Blagoev B, Ong SE, Kratchmarova I, Mann M. Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics. Nature Biotechnology. 22: 1139-45. PMID 15314609 DOI: 10.1038/nbt1005  1
2004 Olsen JV, Ong SE, Mann M. Trypsin cleaves exclusively C-terminal to arginine and lysine residues. Molecular & Cellular Proteomics : McP. 3: 608-14. PMID 15034119 DOI: 10.1074/mcp.T400003-MCP200  1
2003 Ong SE, Kratchmarova I, Mann M. Properties of 13C-substituted arginine in stable isotope labeling by amino acids in cell culture (SILAC). Journal of Proteome Research. 2: 173-81. PMID 12716131 DOI: 10.1021/pr0255708  1
2003 Ong SE, Foster LJ, Mann M. Mass spectrometric-based approaches in quantitative proteomics Methods. 29: 124-130. PMID 12606218 DOI: 10.1016/S1046-2023(02)00303-1  0.6
2003 Blagoev B, Kratchmarova I, Ong SE, Nielsen M, Foster LJ, Mann M. A proteomics strategy to elucidate functional protein-protein interactions applied to EGF signaling Nature Biotechnology. 21: 315-318. PMID 12577067 DOI: 10.1038/nbt790  0.6
2002 Ong SE, Blagoev B, Kratchmarova I, Kristensen DB, Steen H, Pandey A, Mann M. Stable isotope labeling by amino acids in cell culture, SILAC, as a simple and accurate approach to expression proteomics. Molecular & Cellular Proteomics : McP. 1: 376-86. PMID 12118079  1
2002 Mann M, Ong SE, Grønborg M, Steen H, Jensen ON, Pandey A. Analysis of protein phosphorylation using mass spectrometry: deciphering the phosphoproteome. Trends in Biotechnology. 20: 261-8. PMID 12007495 DOI: 10.1016/S0167-7799(02)01944-3  1
2002 Dan I, Ong SE, Watanabe NM, Blagoev B, Nielsen MM, Kajikawa E, Kristiansen TZ, Mann M, Pandey A. Cloning of MASK, a novel member of the mammalian germinal center kinase III subfamily, with apoptosis-inducing properties. The Journal of Biological Chemistry. 277: 5929-39. PMID 11741893 DOI: 10.1074/jbc.M110882200  0.6
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2021 Dasovich M, Beckett MQ, Bailey S, Ong SE, Greenberg MM, Leung AKL. Identifying Poly(ADP-ribose)-Binding Proteins with Photoaffinity-Based Proteomics. Journal of the American Chemical Society. PMID 33596067 DOI: 10.1021/jacs.0c12246  0.16
2019 McPherson RL, Ong SE, Leung AKL. Ion-pairing with triethylammonium acetate improves solid-phase extraction of ADP-ribosylated peptides. Journal of Proteome Research. PMID 31859514 DOI: 10.1021/acs.jproteome.9b00696  0.16
2019 Ando Y, Elkayam E, McPherson RL, Dasovich M, Cheng SJ, Voorneveld J, Filippov DV, Ong SE, Joshua-Tor L, Leung AKL. ELTA: Enzymatic Labeling of Terminal ADP-Ribose. Molecular Cell. PMID 30712989 DOI: 10.1016/j.molcel.2018.12.022  0.16
2018 McPherson RL, Ong SE, Leung AKL. Quantitative Determination of MAR Hydrolase Residue Specificity In Vitro by Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1813: 271-283. PMID 30097875 DOI: 10.1007/978-1-4939-8588-3_19  0.16
2018 Zhang T, Wu YC, Mullane P, Ji YJ, Liu H, He L, Arora A, Hwang HY, Alessi AF, Niaki AG, Periz G, Guo L, Wang H, Elkayam E, Joshua-Tor L, ... ... Ong SE, et al. FUS Regulates Activity of MicroRNA-Mediated Gene Silencing. Molecular Cell. 69: 787-801.e8. PMID 29499134 DOI: 10.1016/j.molcel.2018.02.001  0.16
2017 Daniels CM, Ong SE, Leung AKL. ADP-Ribosylated Peptide Enrichment and Site Identification: The Phosphodiesterase-Based Method. Methods in Molecular Biology (Clifton, N.J.). 1608: 79-93. PMID 28695505 DOI: 10.1007/978-1-4939-6993-7_7  0.16
2015 Daniels CM, Thirawatananond P, Ong SE, Gabelli SB, Leung AK. Nudix hydrolases degrade protein-conjugated ADP-ribose. Scientific Reports. 5: 18271. PMID 26669448 DOI: 10.1038/srep18271  0.16
2018 Jin YN, Schlueter PJ, Jurisch-Yaksi N, Lam PY, Jin S, Hwang WY, Yeh JJ, Yoshigi M, Ong SE, Schenone M, Hartigan CR, Carr SA, Peterson RT. Noncanonical translation via deadenylated 3' UTRs maintains primordial germ cells. Nature Chemical Biology. PMID 29988067 DOI: 10.1038/s41589-018-0098-0  0.08
2021 Beavo JA, Golkowski M, Shimizu-Albergine M, Beltejar MC, Bornfeldt KE, Ong SE. Title: Phosphoproteomic Analysis as an Approach for Understanding Molecular Mechanisms of cAMP-dependent Actions. Molecular Pharmacology. PMID 33574048 DOI: 10.1124/molpharm.120.000197  0.01
2020 Golkowski M, Lau HT, Chan M, Kenerson H, Vidadala VN, Shoemaker A, Maly DJ, Yeung RS, Gujral TS, Ong SE. Pharmacoproteomics Identifies Kinase Pathways that Drive the Epithelial-Mesenchymal Transition and Drug Resistance in Hepatocellular Carcinoma. Cell Systems. PMID 32755597 DOI: 10.1016/j.cels.2020.07.006  0.01
2020 Potter ZE, Lau HT, Chakraborty S, Fang L, Guttman M, Ong SE, Fowler DM, Maly DJ. Parallel Chemoselective Profiling for Mapping Protein Structure. Cell Chemical Biology. PMID 32649906 DOI: 10.1016/j.chembiol.2020.06.014  0.01
2020 Gabrovsek L, Collins KB, Aggarwal S, Saunders LM, Lau HT, Suh D, Sancak Y, Trapnell C, Ong SE, Smith FD, Scott JD. A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. The Journal of Biological Chemistry. PMID 32482893 DOI: 10.1074/jbc.RA120.013454  0.01
2020 Janezic EM, Lauer SM, Williams RG, Chungyoun M, Lee KS, Navaluna E, Lau HT, Ong SE, Hague C. N-glycosylation of α-adrenergic receptor N-terminal domain is required for correct trafficking, function, and biogenesis. Scientific Reports. 10: 7209. PMID 32350295 DOI: 10.1038/s41598-020-64102-4  0.01
2020 Golkowski M, Vidadala VN, Lau HT, Shoemaker A, Shimizu-Albergine M, Beavo J, Maly DJ, Ong SE. Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. Journal of Proteome Research. PMID 32037842 DOI: 10.1021/acs.jproteome.9b00742  0.01
2019 Turnham RE, Smith FD, Kenerson HL, Omar MH, Golkowski M, Garcia I, Bauer R, Lau HT, Sullivan KM, Langeberg LK, Ong SE, Riehle KJ, Yeung RS, Scott JD. An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma. Elife. 8. PMID 31063128 DOI: 10.7554/eLife.44187  0.01
2019 Cherry AE, Vicente JJ, Xu C, Morrison RS, Ong SE, Wordeman L, Stella N. GPR124 regulates microtubule assembly, mitotic progression, and glioblastoma cell proliferation. Glia. PMID 31058365 DOI: 10.1002/glia.23628  0.01
2019 Liu Y, Gibson AW, Levinstein MR, Lesiak AJ, Ong SE, Neumaier J. 5-HT Receptor-Mediated Activation of ERK1/2 Requires Both Gα and β-Arrestin Proteins. Acs Chemical Neuroscience. PMID 30946562 DOI: 10.1021/acschemneuro.8b00596  0.01
2018 Aggarwal S, Gabrovsek L, Langeberg LK, Golkowski M, Ong SE, Smith FD, Scott JD. Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. The Journal of Biological Chemistry. PMID 30598507 DOI: 10.1074/jbc.RA118.006741  0.01
2018 Smith FD, Omar MH, Nygren PJ, Soughayer J, Hoshi N, Lau HT, Snyder CG, Branon TC, Ghosh D, Langeberg LK, Ting AY, Santana LF, Ong SE, Navedo MF, Scott JD. Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 30455320 DOI: 10.1073/pnas.1816614115  0.01
2018 Hsu PL, Li H, Lau HT, Leonen C, Dhall A, Ong SE, Chatterjee C, Zheng N. Crystal Structure of the COMPASS H3K4 Methyltransferase Catalytic Module. Cell. PMID 30100181 DOI: 10.1016/j.cell.2018.06.038  0.01
2018 Golkowski M, Perera GK, Vidadala VN, Ojo KK, Van Voorhis WC, Maly DJ, Ong SE. Kinome chemoproteomics characterization of pyrrolo[3,4-c]pyrazoles as potent and selective inhibitors of glycogen synthase kinase 3. Molecular Omics. 14: 26-36. PMID 29725679 DOI: 10.1039/c7mo00006e  0.01
2017 Schattauer SS, Land BB, Reichard KL, Abraham AD, Burgeno LM, Kuhar JR, Phillips PEM, Ong SE, Chavkin C. Peroxiredoxin 6 mediates Gαi protein-coupled receptor inactivation by cJun kinase. Nature Communications. 8: 743. PMID 28963507 DOI: 10.1038/s41467-017-00791-2  0.01
2017 Golkowski M, Maly DJ, Ong SE. Proteomic Profiling of Protein Kinase Inhibitor Targets by Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 1636: 105-117. PMID 28730476 DOI: 10.1007/978-1-4939-7154-1_8  0.01
2017 Beltejar MG, Lau HT, Golkowski MG, Ong SE, Beavo JA. Analyses of PDE-regulated phosphoproteomes reveal unique and specific cAMP-signaling modules in T cells. Proceedings of the National Academy of Sciences of the United States of America. PMID 28634298 DOI: 10.1073/pnas.1703939114  0.01
2017 McPherson RL, Abraham R, Sreekumar E, Ong SE, Cheng SJ, Baxter VK, Kistemaker HA, Filippov DV, Griffin DE, Leung AK. ADP-ribosylhydrolase activity of Chikungunya virus macrodomain is critical for virus replication and virulence. Proceedings of the National Academy of Sciences of the United States of America. PMID 28143925 DOI: 10.1073/pnas.1621485114  0.01
2017 Golkowski M, Vidadala RS, Lombard CK, Suh HW, Maly DJ, Ong SE. Kinobead and single-shot LC-MS profiling identifies selective PKD inhibitors. Journal of Proteome Research. PMID 28102076 DOI: 10.1021/acs.jproteome.6b00817  0.01
2016 Shimizu-Albergine M, Van Yserloo B, Golkowski MG, Ong SE, Beavo JA, Bornfeldt KE. SCAP/SREBP pathway is required for the full steroidogenic response to cyclic AMP. Proceedings of the National Academy of Sciences of the United States of America. PMID 27601673 DOI: 10.1073/pnas.1611424113  0.01
2016 Palazzo L, Daniels CM, Nettleship JE, Rahman N, McPherson RL, Ong SE, Kato K, Nureki O, Leung AK, Ahel I. ENPP1 processes protein ADP-ribosylation in vitro. The Febs Journal. PMID 27406238 DOI: 10.1111/febs.13811  0.01
2014 Lafranchi L, de Boer HR, de Vries EG, Ong SE, Sartori AA, van Vugt MA. APC/C(Cdh1) controls CtIP stability during the cell cycle and in response to DNA damage. The Embo Journal. 33: 2860-79. PMID 25349192 DOI: 10.15252/embj.201489017  0.01
2014 Golkowski M, Brigham JL, Perera GK, Romano GE, Maly DJ, Ong SE. Rapid profiling of protein kinase inhibitors by quantitative proteomics. Medchemcomm. 5: 363-369. PMID 24648882 DOI: 10.1039/C3MD00315A  0.01
2010 Ong SE. Whole proteomes as internal standards in quantitative proteomics. Genome Medicine. 2: 49. PMID 20678185 DOI: 10.1186/gm170  0.01
2010 Ong SE. Unbiased identification of protein-bait interactions using biochemical enrichment and quantitative proteomics. Cold Spring Harbor Protocols. 2010: pdb.prot5400. PMID 20194469 DOI: 10.1101/pdb.prot5400  0.01
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