Michael E. O'Donnell - Publications

Affiliations: 
1986-1996 Weill Cornell Medical College, New York, NY, United States 
 1996- Rockefeller University, New York, NY, United States 
Area:
DNA Replication
Website:
http://www.rockefeller.edu/research/faculty/labheads/MichaelDonnell/

138 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Yuan Z, Georgescu R, Santos RLA, Zhang D, Bai L, Yao NY, Zhao G, O'Donnell ME, Li H. Ctf4 organizes sister replisomes and Pol α into a replication factory. Elife. 8. PMID 31589141 DOI: 10.7554/eLife.47405  1
2019 Yao NY, O'Donnell ME. Getting ready for DNA duplication. Elife. 8. PMID 31560343 DOI: 10.7554/eLife.51291  0.6
2019 Langston LD, O'Donnell ME. An explanation for origin unwinding in eukaryotes. Elife. 8. PMID 31282859 DOI: 10.7554/eLife.46515  0.72
2018 Mayle R, Langston L, Molloy KR, Zhang D, Chait BT, O'Donnell ME. Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression. Proceedings of the National Academy of Sciences of the United States of America. PMID 30598452 DOI: 10.1073/pnas.1819107116  1
2017 Bai L, Yuan Z, Sun J, Georgescu R, O'Donnell ME, Li H. Architecture of the Saccharomyces cerevisiae Replisome. Advances in Experimental Medicine and Biology. 1042: 207-228. PMID 29357060 DOI: 10.1007/978-981-10-6955-0_10  1
2017 Lewis JS, Spenkelink LM, Schauer GD, Hill FR, Georgescu RE, O'Donnell ME, van Oijen AM. Single-molecule visualization of Saccharomyces cerevisiae leading-strand synthesis reveals dynamic interaction between MTC and the replisome. Proceedings of the National Academy of Sciences of the United States of America. PMID 28923950 DOI: 10.1073/pnas.1711291114  1
2017 Georgescu R, Yuan Z, Bai L, de Luna Almeida Santos R, Sun J, Zhang D, Yurieva O, Li H, O'Donnell ME. Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28096349 DOI: 10.1073/pnas.1620500114  1
2016 Bastia D, Srivastava P, Zaman S, Choudhury M, Mohanty BK, Bacal J, Langston LD, Pasero P, O'Donnell ME. Phosphorylation of CMG helicase and Tof1 is required for programmed fork arrest. Proceedings of the National Academy of Sciences of the United States of America. PMID 27298353 DOI: 10.1073/pnas.1607552113  1
2016 Yuan Z, Bai L, Sun J, Georgescu R, Liu J, O'Donnell ME, Li H. Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation. Nature Structural & Molecular Biology. PMID 26854665 DOI: 10.1038/nsmb.3170  1
2015 Sun J, Shi Y, Georgescu RE, Yuan Z, Chait BT, Li H, O'Donnell ME. The architecture of a eukaryotic replisome. Nature Structural & Molecular Biology. PMID 26524492 DOI: 10.1038/nsmb.3113  1
2015 Georgescu R, Langston L, O'Donnell M. A proposal: Evolution of PCNA's role as a marker of newly replicated DNA. Dna Repair. 29: 4-15. PMID 25704660 DOI: 10.1016/j.dnarep.2015.01.015  1
2014 Langston LD, Zhang D, Yurieva O, Georgescu RE, Finkelstein J, Yao NY, Indiani C, O'Donnell ME. CMG helicase and DNA polymerase ε form a functional 15-subunit holoenzyme for eukaryotic leading-strand DNA replication. Proceedings of the National Academy of Sciences of the United States of America. 111: 15390-5. PMID 25313033 DOI: 10.1073/pnas.1418334111  1
2014 Georgescu RE, Langston L, Yao NY, Yurieva O, Zhang D, Finkelstein J, Agarwal T, O'Donnell ME. Mechanism of asymmetric polymerase assembly at the eukaryotic replication fork. Nature Structural & Molecular Biology. 21: 664-70. PMID 24997598 DOI: 10.1038/nsmb.2851  1
2014 Georgescu RE, Yao N, Indiani C, Yurieva O, O'Donnell ME. Replisome mechanics: lagging strand events that influence speed and processivity. Nucleic Acids Research. 42: 6497-510. PMID 24829446 DOI: 10.1093/nar/gku257  1
2014 Marzahn MR, Hayner JN, Finkelstein J, O'Donnell M, Bloom LB. The ATP sites of AAA+ clamp loaders work together as a switch to assemble clamps on DNA. The Journal of Biological Chemistry. 289: 5537-48. PMID 24436332 DOI: 10.1074/jbc.M113.541466  1
2013 Chiraniya A, Finkelstein J, O'Donnell M, Bloom LB. A novel function for the conserved glutamate residue in the walker B motif of replication factor C. Genes. 4: 134-51. PMID 23946885 DOI: 10.3390/genes4020134  1
2013 Pomerantz RT, Goodman MF, O'Donnell ME. DNA polymerases are error-prone at RecA-mediated recombination intermediates. Cell Cycle (Georgetown, Tex.). 12: 2558-63. PMID 23907132 DOI: 10.4161/cc.25691  1
2013 Yao NY, Schroeder JW, Yurieva O, Simmons LA, O'Donnell ME. Cost of rNTP/dNTP pool imbalance at the replication fork. Proceedings of the National Academy of Sciences of the United States of America. 110: 12942-7. PMID 23882084 DOI: 10.1073/pnas.1309506110  1
2013 O'Donnell M, Langston L, Stillman B. Principles and concepts of DNA replication in bacteria, archaea, and eukarya Cold Spring Harbor Perspectives in Biology. 5. PMID 23818497 DOI: 10.1101/cshperspect.a010108  1
2013 Pomerantz RT, Kurth I, Goodman MF, O'Donnell ME. Preferential D-loop extension by a translesion DNA polymerase underlies error-prone recombination. Nature Structural & Molecular Biology. 20: 748-55. PMID 23686288 DOI: 10.1038/nsmb.2573  1
2013 Barros T, Guenther J, Kelch B, Anaya J, Prabhakar A, O'Donnell M, Kuriyan J, Lamers MH. A structural role for the PHP domain in E. coli DNA polymerase III Bmc Structural Biology. 13. PMID 23672456 DOI: 10.1186/1472-6807-13-8  1
2013 Kurth I, Georgescu RE, O'Donnell ME. A solution to release twisted DNA during chromosome replication by coupled DNA polymerases. Nature. 496: 119-22. PMID 23535600 DOI: 10.1038/nature11988  1
2013 Indiani C, Patel M, Goodman MF, O'Donnell ME. RecA acts as a switch to regulate polymerase occupancy in a moving replication fork. Proceedings of the National Academy of Sciences of the United States of America. 110: 5410-5. PMID 23509251 DOI: 10.1073/pnas.1303301110  1
2013 Indiani C, O'Donnell M. A proposal: Source of single strand DNA that elicits the SOS response. Frontiers in Bioscience (Landmark Edition). 18: 312-23. PMID 23276924 DOI: 10.2741/4102  1
2013 Kurth I, O'Donnell M. New insights into replisome fluidity during chromosome replication. Trends in Biochemical Sciences. 38: 195-203. PMID 23153958 DOI: 10.1016/j.tibs.2012.10.003  1
2012 Yao NY, O'Donnell M. The RFC clamp loader: structure and function. Sub-Cellular Biochemistry. 62: 259-79. PMID 22918590 DOI: 10.1007/978-94-007-4572-8_14  1
2012 Langston LD, O'Donnell M. Subunit sharing among high- and low-fidelity DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 109: 12268-9. PMID 22826240 DOI: 10.1073/pnas.1209533109  1
2012 Kelch BA, Makino DL, O'Donnell M, Kuriyan J. Clamp loader ATPases and the evolution of DNA replication machinery Bmc Biology. 10. PMID 22520345 DOI: 10.1186/1741-7007-10-34  1
2012 Firestone AJ, Weinger JS, Maldonado M, Barlan K, Langston LD, O'Donnell M, Gelfand VI, Kapoor TM, Chen JK. Small-molecule inhibitors of the AAA+ ATPase motor cytoplasmic dynein. Nature. 484: 125-9. PMID 22425997 DOI: 10.1038/nature10936  1
2012 Sakato M, O'Donnell M, Hingorani MM. A central swivel point in the RFC clamp loader controls PCNA opening and loading on DNA. Journal of Molecular Biology. 416: 163-75. PMID 22197374 DOI: 10.1016/j.jmb.2011.12.017  1
2012 Thompson JA, Marzahn MR, O'Donnell M, Bloom LB. Replication factor C is a more effective proliferating cell nuclear antigen (PCNA) opener than the checkpoint clamp loader, Rad24-RFC. The Journal of Biological Chemistry. 287: 2203-9. PMID 22115746 DOI: 10.1074/jbc.C111.318899  1
2012 Kelch B, Makino D, Simonetta K, O'Donnell M, Kuriyan J. Molecular mechanisms of DNA polymerase clamp loaders Nato Science For Peace and Security Series a: Chemistry and Biology. 103-114. DOI: 10.1007/978-94-007-2530-0_10  1
2011 Paschall CO, Thompson JA, Marzahn MR, Chiraniya A, Hayner JN, O'Donnell M, Robbins AH, McKenna R, Bloom LB. The Escherichia coli clamp loader can actively pry open the β-sliding clamp. The Journal of Biological Chemistry. 286: 42704-14. PMID 21971175 DOI: 10.1074/jbc.M111.268169  1
2011 Kelch BA, Makino DL, O'Donnell M, Kuriyan J. How a DNA polymerase clamp loader opens a sliding clamp Science. 334: 1675-1680. DOI: 10.1126/science.1211884  1
2010 Pomerantz RT, O'Donnell M. What happens when replication and transcription complexes collide? Cell Cycle (Georgetown, Tex.). 9: 2537-43. PMID 20581460 DOI: 10.4161/cc.9.13.12122  1
2010 Yao NY, O'Donnell M. SnapShot: The replisome. Cell. 141: 1088, 1088.e1. PMID 20550941 DOI: 10.1016/j.cell.2010.05.042  1
2010 Pomerantz RT, O'Donnell M. Direct restart of a replication fork stalled by a head-on RNA polymerase. Journal of Visualized Experiments : Jove. PMID 20436399 DOI: 10.3791/1919  1
2010 Georgescu RE, Yao NY, O'Donnell M. Single-molecule analysis of the Escherichia coli replisome and use of clamps to bypass replication barriers. Febs Letters. 584: 2596-605. PMID 20388515 DOI: 10.1016/j.febslet.2010.04.003  1
2010 Park AY, Jergic S, Politis A, Ruotolo BT, Hirshberg D, Jessop LL, Beck JL, Barsky D, O'Donnell M, Dixon NE, Robinson CV. A single subunit directs the assembly of the Escherichia coli DNA sliding clamp loader. Structure (London, England : 1993). 18: 285-92. PMID 20223211 DOI: 10.1016/j.str.2010.01.009  1
2010 McNally R, Bowman GD, Goedken ER, O'Donnell M, Kuriyan J. Analysis of the role of PCNA-DNA contacts during clamp loading. Bmc Structural Biology. 10: 3. PMID 20113510 DOI: 10.1186/1472-6807-10-3  1
2010 Pomerantz RT, O'Donnell M. Direct restart of a replication fork stalled by a head-on RNA polymerase. Science (New York, N.Y.). 327: 590-2. PMID 20110508 DOI: 10.1126/science.1179595  1
2009 Kurth I, O'Donnell M. Replisome Dynamics during Chromosome Duplication. Ecosal Plus. 3. PMID 26443767 DOI: 10.1128/ecosalplus.4.4.2  1
2009 Pluciennik A, Burdett V, Lukianova O, O'Donnell M, Modrich P. Involvement of the beta clamp in methyl-directed mismatch repair in vitro. The Journal of Biological Chemistry. 284: 32782-91. PMID 19783657 DOI: 10.1074/jbc.M109.054528  1
2009 Park MS, O'Donnell M. The clamp loader assembles the beta clamp onto either a 3' or 5' primer terminus: the underlying basis favoring 3' loading. The Journal of Biological Chemistry. 284: 31473-83. PMID 19759020 DOI: 10.1074/jbc.M109.050310  1
2009 Thompson JA, Paschall CO, O'Donnell M, Bloom LB. A slow ATP-induced conformational change limits the rate of DNA binding but not the rate of beta clamp binding by the escherichia coli gamma complex clamp loader. The Journal of Biological Chemistry. 284: 32147-57. PMID 19759003 DOI: 10.1074/jbc.M109.045997  1
2009 Georgescu RE, Kurth I, Yao NY, Stewart J, Yurieva O, O'Donnell M. Mechanism of polymerase collision release from sliding clamps on the lagging strand. The Embo Journal. 28: 2981-91. PMID 19696739 DOI: 10.1038/emboj.2009.233  1
2009 Yao NY, Georgescu RE, Finkelstein J, O'Donnell ME. Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression. Proceedings of the National Academy of Sciences of the United States of America. 106: 13236-41. PMID 19666586 DOI: 10.1073/pnas.0906157106  1
2009 Anderson SG, Thompson JA, Paschall CO, O'Donnell M, Bloom LB. Temporal correlation of DNA binding, ATP hydrolysis, and clamp release in the clamp loading reaction catalyzed by the Escherichia coli gamma complex. Biochemistry. 48: 8516-27. PMID 19663416 DOI: 10.1021/bi900912a  1
2009 Langston LD, Indiani C, O'Donnell M. Whither the replisome: emerging perspectives on the dynamic nature of the DNA replication machinery. Cell Cycle (Georgetown, Tex.). 8: 2686-91. PMID 19652539  1
2009 Simonetta KR, Kazmirski SL, Goedken ER, Cantor AJ, Kelch BA, McNally R, Seyedin SN, Makino DL, O'Donnell M, Kuriyan J. The mechanism of ATP-dependent primer-template recognition by a clamp loader complex. Cell. 137: 659-71. PMID 19450514 DOI: 10.1016/j.cell.2009.03.044  1
2009 Yao NY, O'Donnell M. Replisome structure and conformational dynamics underlie fork progression past obstacles. Current Opinion in Cell Biology. 21: 336-43. PMID 19375905 DOI: 10.1016/j.ceb.2009.02.008  1
2009 Indiani C, Langston LD, Yurieva O, Goodman MF, O'Donnell M. Translesion DNA polymerases remodel the replisome and alter the speed of the replicative helicase. Proceedings of the National Academy of Sciences of the United States of America. 106: 6031-8. PMID 19279203 DOI: 10.1073/pnas.0901403106  1
2008 Lamers MH, O'Donnell M. A consensus view of DNA binding by the C family of replicative DNA polymerases. Proceedings of the National Academy of Sciences of the United States of America. 105: 20565-6. PMID 19106294 DOI: 10.1073/pnas.0811279106  1
2008 Pomerantz RT, O'Donnell M. The replisome uses mRNA as a primer after colliding with RNA polymerase. Nature. 456: 762-6. PMID 19020502 DOI: 10.1038/nature07527  1
2008 Minko IG, Yamanaka K, Kozekov ID, Kozekova A, Indiani C, O'Donnell ME, Jiang Q, Goodman MF, Rizzo CJ, Lloyd RS. Replication bypass of the acrolein-mediated deoxyguanine DNA-peptide cross-links by DNA polymerases of the DinB family. Chemical Research in Toxicology. 21: 1983-90. PMID 18788757 DOI: 10.1021/tx800174a  1
2008 Georgescu RE, Yurieva O, Kim SS, Kuriyan J, Kong XP, O'Donnell M. Structure of a small-molecule inhibitor of a DNA polymerase sliding clamp Proceedings of the National Academy of Sciences of the United States of America. 105: 11116-11121. PMID 18678908 DOI: 10.1073/pnas.0804754105  1
2008 Langston LD, O'Donnell M. DNA polymerase delta is highly processive with proliferating cell nuclear antigen and undergoes collision release upon completing DNA. The Journal of Biological Chemistry. 283: 29522-31. PMID 18635534 DOI: 10.1074/jbc.M804488200  1
2008 Laurence TA, Kwon Y, Johnson A, Hollars CW, O'Donnell M, Camarero JA, Barsky D. Motion of a DNA sliding clamp observed by single molecule fluorescence spectroscopy. The Journal of Biological Chemistry. 283: 22895-906. PMID 18556658 DOI: 10.1074/jbc.M800174200  1
2008 Chen S, Coman MM, Sakato M, O'Donnell M, Hingorani MM. Conserved residues in the δ subunit help the E. coli clamp loader, γ complex, target primer-template DNA for clamp assembly Nucleic Acids Research. 36: 3274-3286. PMID 18424802 DOI: 10.1093/nar/gkn157  1
2008 Georgescu RE, Kim SS, Yurieva O, Kuriyan J, Kong XP, O'Donnell M. Structure of a Sliding Clamp on DNA Cell. 132: 43-54. PMID 18191219 DOI: 10.1016/j.cell.2007.11.045  1
2007 Kadyrov FA, Holmes SF, Arana ME, Lukianova OA, O'Donnell M, Kunkel TA, Modrich P. Saccharomyces cerevisiae MutLalpha is a mismatch repair endonuclease. The Journal of Biological Chemistry. 282: 37181-90. PMID 17951253 DOI: 10.1074/jbc.M707617200  1
2007 Georgescu RE, O'Donnell M. Structural biology. Getting DNA to unwind. Science (New York, N.Y.). 317: 1181-2. PMID 17761872 DOI: 10.1126/science.1147795  1
2007 McInerney P, Johnson A, Katz F, O'Donnell M. Characterization of a triple DNA polymerase replisome. Molecular Cell. 27: 527-38. PMID 17707226 DOI: 10.1016/j.molcel.2007.06.019  1
2007 McInerney P, O'Donnell M. Replisome fate upon encountering a leading strand block and clearance from DNA by recombination proteins. The Journal of Biological Chemistry. 282: 25903-16. PMID 17609212 DOI: 10.1074/jbc.M703777200  1
2007 Pomerantz RT, O'Donnell M. Replisome mechanics: insights into a twin DNA polymerase machine. Trends in Microbiology. 15: 156-64. PMID 17350265 DOI: 10.1016/j.tim.2007.02.007  1
2007 Anderson SG, Williams CR, O'donnell M, Bloom LB. A function for the psi subunit in loading the Escherichia coli DNA polymerase sliding clamp. The Journal of Biological Chemistry. 282: 7035-45. PMID 17210572 DOI: 10.1074/jbc.M610136200  1
2006 Johnson A, Yao NY, Bowman GD, Kuriyan J, O'Donnell M. The replication factor C clamp loader requires arginine finger sensors to drive DNA binding and proliferating cell nuclear antigen loading. The Journal of Biological Chemistry. 281: 35531-43. PMID 16980295 DOI: 10.1074/jbc.M606090200  1
2006 Lamers MH, Georgescu RE, Lee SG, O'Donnell M, Kuriyan J. Crystal Structure of the Catalytic α Subunit of E. coli Replicative DNA Polymerase III Cell. 126: 881-892. PMID 16959568 DOI: 10.1016/j.cell.2006.07.028  1
2006 Indiani C, O'Donnell M. The replication clamp-loading machine at work in the three domains of life. Nature Reviews. Molecular Cell Biology. 7: 751-61. PMID 16955075 DOI: 10.1038/nrm2022  1
2006 O'Donnell M, Jeruzalmi D. Helical proteins initiate replication of DNA helices. Nature Structural & Molecular Biology. 13: 665-7. PMID 16886004 DOI: 10.1038/nsmb0806-665  1
2006 Langston LD, O'Donnell M. DNA replication: keep moving and don't mind the gap. Molecular Cell. 23: 155-60. PMID 16857582 DOI: 10.1016/j.molcel.2006.05.034  1
2006 Yao NY, Johnson A, Bowman GD, Kuriyan J, O'Donnell M. Mechanism of proliferating cell nuclear antigen clamp opening by replication factor C. The Journal of Biological Chemistry. 281: 17528-39. PMID 16608854 DOI: 10.1074/jbc.M601273200  1
2006 López de Saro FJ, Marinus MG, Modrich P, O'Donnell M. The beta sliding clamp binds to multiple sites within MutL and MutS. The Journal of Biological Chemistry. 281: 14340-9. PMID 16546997 DOI: 10.1074/jbc.M601264200  1
2006 O'Donnell M. Replisome architecture and dynamics in Escherichia coli. The Journal of Biological Chemistry. 281: 10653-6. PMID 16421093 DOI: 10.1074/jbc.R500028200  1
2006 Argiriadi MA, Goedken ER, Bruck I, O'Donnell M, Kuriyan J. Crystal structure of a DNA polymerase sliding clamp from a Gram-positive bacterium. Bmc Structural Biology. 6: 2. PMID 16403212 DOI: 10.1186/1472-6807-6-2  1
2006 O'Donnell M, Kuriyan J. Clamp loaders and replication initiation Current Opinion in Structural Biology. 16: 35-41. PMID 16377178 DOI: 10.1016/j.sbi.2005.12.004  1
2006 Kaplan DL, O'Donnell M. RuvA is a sliding collar that protects Holliday junctions from unwinding while promoting branch migration. Journal of Molecular Biology. 355: 473-90. PMID 16324713 DOI: 10.1016/j.jmb.2005.10.075  1
2005 Kazmirski SL, Zhao Y, Bowman GD, O'Donnell M, Kuriyan J. Out-of-plane motions in open sliding clamps: Molecular dynamics simulations of eukaryotic and archaeal proliferating cell nuclear antigen Proceedings of the National Academy of Sciences of the United States of America. 102: 13801-13806. PMID 16169903 DOI: 10.1073/pnas.0506430102  1
2005 Indiani C, McInerney P, Georgescu R, Goodman MF, O'Donnell M. A sliding-clamp toolbelt binds high- and low-fidelity DNA polymerases simultaneously. Molecular Cell. 19: 805-15. PMID 16168375 DOI: 10.1016/j.molcel.2005.08.011  1
2005 Johnson A, O'Donnell M. Cellular DNA replicases: components and dynamics at the replication fork. Annual Review of Biochemistry. 74: 283-315. PMID 15952889 DOI: 10.1146/annurev.biochem.73.011303.073859  1
2005 Tackett AJ, Dilworth DJ, Davey MJ, O'Donnell M, Aitchison JD, Rout MP, Chait BT. Proteomic and genomic characterization of chromatin complexes at a boundary. The Journal of Cell Biology. 169: 35-47. PMID 15824130 DOI: 10.1083/jcb.200502104  1
2005 Johnson A, O'Donnell M. DNA ligase: getting a grip to seal the deal. Current Biology : Cb. 15: R90-2. PMID 15694297 DOI: 10.1016/j.cub.2005.01.025  1
2005 Bowman GD, Goedken ER, Kazmirski SL, O'Donnell M, Kuriyan J. DNA polymerase clamp loaders and DNA recognition. Febs Letters. 579: 863-7. PMID 15680964 DOI: 10.1016/j.febslet.2004.11.038  1
2005 Goedken ER, Kazmirski SL, Bowman GD, O'Donnell M, Kuriyan J. Mapping the interaction of DNA with the Escherichia coli DNA polymerase clamp loader complex. Nature Structural & Molecular Biology. 12: 183-90. PMID 15665871 DOI: 10.1038/nsmb889  1
2005 Bruck I, Georgescu RE, O'Donnell M. Conserved interactions in the Staphylococcus aureus DNA PolC chromosome replication machine. The Journal of Biological Chemistry. 280: 18152-62. PMID 15647255 DOI: 10.1074/jbc.M413595200  1
2004 Kazmirski SL, Podobnik M, Weitze TF, O'Donnell M, Kuriyan J. Structural analysis of the inactive state of the Escherichia coli DNA polymerase clamp-loader complex Proceedings of the National Academy of Sciences of the United States of America. 101: 16750-16755. PMID 15556993 DOI: 10.1073/pnas.0407904101  1
2004 Magdalena Coman M, Jin M, Ceapa R, Finkelstein J, O'Donnell M, Chait BT, Hingorani MM. Dual functions, clamp opening and primer-template recognition, define a key clamp loader subunit. Journal of Molecular Biology. 342: 1457-69. PMID 15364574 DOI: 10.1016/j.jmb.2004.07.097  1
2004 Kaplan DL, O'Donnell M. Twin DNA pumps of a hexameric helicase provide power to simultaneously melt two duplexes. Molecular Cell. 15: 453-65. PMID 15304224 DOI: 10.1016/j.molcel.2004.06.039  1
2004 Harrison SC, Alberts B, Ehrenfeld E, Enquist L, Fineberg H, McKnight SL, Moss B, O'Donnell M, Ploegh H, Schmid SL, Walter KP, Theriot J. Discovery of antivirals against smallpox. Proceedings of the National Academy of Sciences of the United States of America. 101: 11178-92. PMID 15249657 DOI: 10.1073/pnas.0403600101  1
2004 Bertram JG, Bloom LB, O'Donnell M, Goodman MF. Increased dNTP binding affinity reveals a nonprocessive role for Escherichia coli beta clamp with DNA polymerase IV. The Journal of Biological Chemistry. 279: 33047-50. PMID 15210708 DOI: 10.1074/jbc.C400265200  1
2004 Bowman GD, O'Donnell M, Kuriyan J. Structural analysis of a eukaryotic sliding DNA clamp-clamp loader complex Nature. 429: 724-730. PMID 15201901 DOI: 10.1038/nature02585  1
2004 López de Saro F, Georgescu RE, Leu F, O'Donnell M. Protein trafficking on sliding clamps. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 359: 25-30. PMID 15065653 DOI: 10.1098/rstb.2003.1361  1
2004 Goedken ER, Levitus M, Johnson A, Bustamante C, O'Donnell M, Kuriyan J. Fluorescence measurements on the E.coli DNA polymerase clamp loader: implications for conformational changes during ATP and clamp binding. Journal of Molecular Biology. 336: 1047-59. PMID 15037068 DOI: 10.1016/j.jmb.2003.12.074  1
2004 McInerney P, O'Donnell M. Functional uncoupling of twin polymerases: mechanism of polymerase dissociation from a lagging-strand block. The Journal of Biological Chemistry. 279: 21543-51. PMID 15014081 DOI: 10.1074/jbc.M401649200  1
2004 Gulbis JM, Kazmirski SL, Finkelstein J, Kelman Z, O'Donnell M, Kuriyan J. Crystal structure of the chi:psi subassembly of the Escherichia coli DNA polymerase clamp-loader complex European Journal of Biochemistry. 271: 439-449. PMID 14717711 DOI: 10.1046/j.1432-1033.2003.03944.x  1
2004 Snyder AK, Williams CR, Johnson A, O'Donnell M, Bloom LB. Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: II. Uncoupling the beta and DNA binding activities of the gamma complex. The Journal of Biological Chemistry. 279: 4386-93. PMID 14610068 DOI: 10.1074/jbc.M310430200  1
2004 Williams CR, Snyder AK, Kuzmic P, O'Donnell M, Bloom LB. Mechanism of loading the Escherichia coli DNA polymerase III sliding clamp: I. Two distinct activities for individual ATP sites in the gamma complex. The Journal of Biological Chemistry. 279: 4376-85. PMID 14610067 DOI: 10.1074/jbc.M310429200  1
2003 López de Saro FJ, Georgescu RE, Goodman MF, O'Donnell M. Competitive processivity-clamp usage by DNA polymerases during DNA replication and repair. The Embo Journal. 22: 6408-18. PMID 14633999 DOI: 10.1093/emboj/cdg603  1
2003 López de Saro FJ, Georgescu RE, O'Donnell M. A peptide switch regulates DNA polymerase processivity. Proceedings of the National Academy of Sciences of the United States of America. 100: 14689-94. PMID 14630952 DOI: 10.1073/pnas.2435454100  1
2003 Yao N, Coryell L, Zhang D, Georgescu RE, Finkelstein J, Coman MM, Hingorani MM, O'Donnell M. Replication factor C clamp loader subunit arrangement within the circular pentamer and its attachment points to proliferating cell nuclear antigen. The Journal of Biological Chemistry. 278: 50744-53. PMID 14530260 DOI: 10.1074/jbc.M309206200  1
2003 Kaplan DL, Davey MJ, O'Donnell M. Mcm4,6,7 uses a "pump in ring" mechanism to unwind DNA by steric exclusion and actively translocate along a duplex. The Journal of Biological Chemistry. 278: 49171-82. PMID 13679365 DOI: 10.1074/jbc.M308074200  1
2003 Kaplan DL, O'Donnell M. Rho factor: transcription termination in four steps. Current Biology : Cb. 13: R714-6. PMID 13678611 DOI: 10.1016/j.cub.2003.08.047  1
2003 Bruck I, Goodman MF, O'Donnell M. The essential C family DnaE polymerase is error-prone and efficient at lesion bypass. The Journal of Biological Chemistry. 278: 44361-8. PMID 12949067 DOI: 10.1074/jbc.M308307200  1
2003 Indiani C, O'Donnell M. Mechanism of the delta wrench in opening the beta sliding clamp. The Journal of Biological Chemistry. 278: 40272-81. PMID 12851392 DOI: 10.1074/jbc.M305828200  1
2003 Finkelstein J, Antony E, Hingorani MM, O'Donnell M. Overproduction and analysis of eukaryotic multiprotein complexes in Escherichia coli using a dual-vector strategy. Analytical Biochemistry. 319: 78-87. PMID 12842110 DOI: 10.1016/S0003-2697(03)00273-2  1
2003 Leu FP, Georgescu R, O'Donnell M. Mechanism of the E. coli tau processivity switch during lagging-strand synthesis. Molecular Cell. 11: 315-27. PMID 12620221 DOI: 10.1016/S1097-2765(03)00042-X  1
2003 Ason B, Handayani R, Williams CR, Bertram JG, Hingorani MM, O'Donnell M, Goodman MF, Bloom LB. Mechanism of loading the Escherichia coli DNA polymerase III beta sliding clamp on DNA. Bona fide primer/templates preferentially trigger the gamma complex to hydrolyze ATP and load the clamp. The Journal of Biological Chemistry. 278: 10033-40. PMID 12519754 DOI: 10.1074/jbc.M211741200  1
2001 Leu FP, O'Donnell M. Interplay of clamp loader subunits in opening the beta sliding clamp of Escherichia coli DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 276: 47185-94. PMID 11572866 DOI: 10.1074/jbc.M106780200  1
2001 Jeruzalmi D, Yurieva O, Zhao Y, Young M, Stewart J, Hingorani M, O'Donnell M, Kuriyan J. Mechanism of processivity clamp opening by the delta subunit wrench of the clamp loader complex of E. coli DNA polymerase III. Cell. 106: 417-28. PMID 11525728 DOI: 10.1016/S0092-8674(01)00462-7  1
2001 Stewart J, Hingorani MM, Kelman Z, O'Donnell M. Mechanism of beta clamp opening by the delta subunit of Escherichia coli DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 276: 19182-9. PMID 11279099 DOI: 10.1074/jbc.M100592200  1
2000 Hingorani MM, O'Donnell M. A tale of toroids in DNA metabolism. Nature Reviews. Molecular Cell Biology. 1: 22-30. PMID 11413486 DOI: 10.1038/35036044  1
2000 Leu FP, Hingorani MM, Turner J, O'Donnell M. The delta subunit of DNA polymerase III holoenzyme serves as a sliding clamp unloader in Escherichia coli. The Journal of Biological Chemistry. 275: 34609-18. PMID 10924523 DOI: 10.1074/jbc.M005495200  1
2000 Bertram JG, Bloom LB, Hingorani MM, Beechem JM, O'Donnell M, Goodman MF. Molecular mechanism and energetics of clamp assembly in Escherichia coli. The role of ATP hydrolysis when gamma complex loads beta on DNA. The Journal of Biological Chemistry. 275: 28413-20. PMID 10874049 DOI: 10.1074/jbc.M910441199  1
2000 Yao N, Leu FP, Anjelkovic J, Turner J, O'Donnell M. DNA structure requirements for the Escherichia coli gamma complex clamp loader and DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 275: 11440-50. PMID 10753961 DOI: 10.1074/jbc.275.15.11440  1
2000 Hingorani MM, O'Donnell M. Sliding clamps: a (tail)ored fit. Current Biology : Cb. 10: R25-9. PMID 10660290  1
2000 Ason B, Bertram JG, Hingorani MM, Beechem JM, O'Donnell M, Goodman MF, Bloom LB. A model for Escherichia coli DNA polymerase III holoenzyme assembly at primer/template ends. DNA triggers a change in binding specificity of the gamma complex clamp loader. The Journal of Biological Chemistry. 275: 3006-15. PMID 10644772 DOI: 10.1074/jbc.275.4.3006  1
1999 Hingorani MM, Bloom LB, Goodman MF, O'Donnell M. Division of labor--sequential ATP hydrolysis drives assembly of a DNA polymerase sliding clamp around DNA. The Embo Journal. 18: 5131-44. PMID 10487764 DOI: 10.1093/emboj/18.18.5131  1
1999 Turner J, Hingorani MM, Kelman Z, O'Donnell M. The internal workings of a DNA polymerase clamp-loading machine Embo Journal. 18: 771-783. PMID 9927437 DOI: 10.1093/emboj/18.3.771  1
1998 Hingorani MM, O'Donnell M. ATP binding to the Escherichia coli clamp loader powers opening of the ring-shaped clamp of DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 273: 24550-63. PMID 9733750  1
1998 Hingorani MM, O'Donnell M. Toroidal proteins: running rings around DNA. Current Biology : Cb. 8: R83-6. PMID 9443909  1
1996 Yao N, Turner J, Kelman Z, Todd Stukenberg P, Dean F, Shechter D, Pan ZQ, Hurwitz J, O'Donnell M. Clamp loading, unloading and intrinsic stability of the PCNA, β and gp45 sliding clamps of human, E. coli and T4 replicases Genes to Cells. 1: 101-113. PMID 9078370  1
1995 Stukenberg PT, O'Donnell M. Assembly of a chromosomal replication machine: two DNA polymerases, a clamp loader, and sliding clamps in one holoenzyme particle. V. Four different polymerase-clamp complexes on DNA. The Journal of Biological Chemistry. 270: 13384-91. PMID 7768940  1
1994 Stukenberg PT, Turner J, O'Donnell M. An explanation for lagging strand replication: polymerase hopping among DNA sliding clamps. Cell. 78: 877-87. PMID 8087854  1
1993 Blinkova A, Hervas C, Stukenberg PT, Onrust R, O'Donnell ME, Walker JR. The Escherichia coli DNA polymerase III holoenzyme contains both products of the dnaX gene, tau and gamma, but only tau is essential. Journal of Bacteriology. 175: 6018-27. PMID 8376347  1
1992 Bonner CA, Stukenberg PT, Rajagopalan M, Eritja R, O'Donnell M, McEntee K, Echols H, Goodman MF. Processive DNA synthesis by DNA polymerase II mediated by DNA polymerase III accessory proteins. The Journal of Biological Chemistry. 267: 11431-8. PMID 1534562  1
1992 O'Donnell M, Kuriyan J, Kong XP, Stukenberg PT, Onrust R. The sliding clamp of DNA polymerase III holoenzyme encircles DNA Molecular Biology of the Cell. 3: 953-957. PMID 1358275  1
1991 Stukenberg PT, Studwell-Vaughan PS, O'Donnell M. Mechanism of the sliding beta-clamp of DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 266: 11328-34. PMID 2040637  1
1991 Onrust R, Stukenberg PT, O'Donnell M. Analysis of the ATPase subassembly which initiates processive DNA synthesis by DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 266: 21681-6. PMID 1657977  1
1987 O'Donnell ME, Elias P, Funnell BE, Lehman IR. Interaction between the DNA polymerase and single-stranded DNA-binding protein (infected cell protein 8) of herpes simplex virus 1. The Journal of Biological Chemistry. 262: 4260-6. PMID 3031068  1
1987 O'Donnell ME, Elias P, Lehman IR. Processive replication of single-stranded DNA templates by the herpes simplex virus-induced DNA polymerase. The Journal of Biological Chemistry. 262: 4252-9. PMID 3031067  1
1986 Elias P, O'Donnell ME, Mocarski ES, Lehman IR. A DNA binding protein specific for an origin of replication of herpes simplex virus type 1. Proceedings of the National Academy of Sciences of the United States of America. 83: 6322-6. PMID 3018724  1
1985 O'Donnell ME, Williams CH. Reaction of both active site thiols of reduced thioredoxin reductase with N-ethylmaleimide. Biochemistry. 24: 7617-21. PMID 3912005  1
1985 O'Donnell ME, Kornberg A. Complete replication of templates by Escherichia coli DNA polymerase III holoenzyme. The Journal of Biological Chemistry. 260: 12884-9. PMID 2413036  1
1985 O'Donnell ME, Kornberg A. Dynamics of DNA polymerase III holoenzyme of Escherichia coli in replication of a multiprimed template. The Journal of Biological Chemistry. 260: 12875-83. PMID 2413035  1
1984 O'Donnell ME, Williams CH. Graphical analysis of interactions between oxidation-reduction sites in two site oxidation-reduction proteins. Analytical Biochemistry. 136: 235-46. PMID 6370035 DOI: 10.1016/0003-2697(84)90330-0  1
1984 O'Donnell ME, Williams CH. Reconstitution of Escherichia coli thioredoxin reductase with 1-deazaFAD. Evidence for 1-deazaFAD C-4a adduct formation linked to the ionization of an active site base. The Journal of Biological Chemistry. 259: 2243-51. PMID 6365906  1
1983 O'Donnell ME, Johnson FA, Williams CH. Proton nuclear magnetic resonance investigation of the mechanism of flavin C-4a adduct formation induced by oxidized nicotinamide adenine dinucleotide binding to monoalkylated pig heart lipoamide dehydrogenase. Biochemistry. 22: 3792-6. PMID 6688532  1
1983 O'Donnell ME, Williams CH. Proton stoichiometry in the reduction of the FAD and disulfide of Escherichia coli thioredoxin reductase. Evidence for a base at the active site. The Journal of Biological Chemistry. 258: 13795-805. PMID 6358211  1
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