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Duncan L. Browne - Publications

Affiliations: 
University College London, London, United Kingdom 
Area:
Organic Chemistry
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78 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Priestley I, Battilocchio C, Iosub A, Barreteau F, Bluck GW, Ling KB, Ingram K, Ciaccia M, Leitch JA, Browne DL. Correction to "Safety Considerations and Proposed Workflow for Laboratory Scale Chemical Synthesis by Ball Milling". Organic Process Research & Development. 27: 1154. PMID 37342801 DOI: 10.1021/acs.oprd.3c00155  0.613
2022 Del Vecchio A, Smallman HR, Morvan J, McBride T, Browne DL, Mauduit M. Challenges Arising from Continuous Flow Olefin Metathesis. Angewandte Chemie (International Ed. in English). PMID 36111496 DOI: 10.1002/anie.202209564  0.33
2022 Smallman HR, Brancaglion GA, Pastre JC, Browne DL. Continuous Flow Generation of Acylketene Intermediates via Nitrogen Extrusion. The Journal of Organic Chemistry. 87: 12297-12305. PMID 36047721 DOI: 10.1021/acs.joc.2c01486  0.358
2021 Nicholson W, Barreteau F, Leitch J, Payne R, Priestley I, Godineau E, Battilocchio C, Browne DL. Direct Amidation of Esters via Ball Milling. Angewandte Chemie (International Ed. in English). PMID 34357668 DOI: 10.1002/anie.202106412  0.683
2021 Morvan J, McBride T, Curbet I, Colombel-Rouen S, Roisnel T, Crévisy C, Browne DL, Mauduit M. Continuous Flow Z-stereoselective Olefin Metathesis: Development and Applications in the Synthesis of Pheromones and Macrocyclic Odorant Molecules. Angewandte Chemie (International Ed. in English). PMID 34184375 DOI: 10.1002/anie.202106410  0.316
2020 Jones AC, Nicholson WI, Smallman HR, Browne DL. A Robust Pd-Catalyzed C-S Cross-Coupling Process Enabled by Ball-Milling. Organic Letters. PMID 32941045 DOI: 10.1021/Acs.Orglett.0C02418  0.384
2020 Pastre JC, Murray PRD, Browne DL, Brancaglion GA, Galaverna RS, Pilli RA, Ley SV. Integrated Batch and Continuous Flow Process for the Synthesis of Goniothalamin. Acs Omega. 5: 18472-18483. PMID 32743225 DOI: 10.1021/acsomega.0c02390  0.521
2020 Yin J, Stark RT, Fallis IA, Browne DL. A Mechanochemical Zinc-Mediated Barbier-Type Allylation Reaction under Ball-Milling Conditions. The Journal of Organic Chemistry. PMID 31913623 DOI: 10.1021/Acs.Joc.9B02876  0.382
2019 Nicholson WI, Seastram AC, Iqbal SA, Reed-Berendt BG, Morrill LC, Browne DL. N-Heterocyclic Carbene Acyl Anion Organocatalysis by Ball-Milling. Chemsuschem. PMID 31774627 DOI: 10.1002/Cssc.201902346  0.365
2019 Allen BDW, Hareram MD, Seastram AC, McBride T, Wirth T, Browne DL, Morrill LC. Manganese-Catalyzed Electrochemical Deconstructive Chlorination of Cycloalkanols via Alkoxy Radicals. Organic Letters. PMID 31687826 DOI: 10.1021/Acs.Orglett.9B03652  0.375
2019 Cao Q, Stark R, Fallis I, Browne DL. A Ball-Milling Enabled Reformatsky Reaction. Chemsuschem. PMID 31033237 DOI: 10.1002/Cssc.201900886  0.381
2019 Laudadio G, Barmpoutsis E, Schotten C, Struik L, Govaerts S, Browne DL, Noël T. Sulfonamide Synthesis through Electrochemical Oxidative Coupling of Amines and Thiols. Journal of the American Chemical Society. PMID 30905146 DOI: 10.1021/Jacs.9B02266  0.4
2019 Carden JL, Gierlichs LJ, Wass DF, Browne DL, Melen RL. Unlocking the catalytic potential of tris(3,4,5-trifluorophenyl)borane with microwave irradiation. Chemical Communications (Cambridge, England). 55: 318-321. PMID 30534764 DOI: 10.1039/C8Cc09459D  0.355
2019 Galaverna R, McBride T, Pastre JC, Browne DL. Exploring the generation and use of acylketenes with continuous flow processes Reaction Chemistry and Engineering. 4: 1559-1564. DOI: 10.1039/C9Re00072K  0.441
2019 Galaverna R, Fernandes LP, Browne DL, Pastre JC. Continuous flow processing as a tool for the generation of terpene-derived monomer libraries Reaction Chemistry and Engineering. 4: 362-367. DOI: 10.1039/C8Re00237A  0.431
2018 Howard JL, Brand MC, Browne DL. Switching Chemoselectivity: Using Mechanochemistry to Alter Reaction Kinetics. Angewandte Chemie (International Ed. in English). PMID 30335216 DOI: 10.1002/Anie.201810141  0.358
2018 Cao Q, Nicholson WI, Jones AC, Browne DL. Robust Buchwald-Hartwig amination enabled by ball-milling. Organic & Biomolecular Chemistry. PMID 30226258 DOI: 10.1039/C8Ob01781F  0.304
2018 Cao Q, Howard JL, Wheatley E, Browne DL. Mechanochemical Activation of Zinc and Application to Negishi Cross-Coupling. Angewandte Chemie (International Ed. in English). PMID 30015403 DOI: 10.1002/Anie.201806480  0.352
2018 Howard JL, Cao Q, Browne DL. Mechanochemistry as an emerging tool for molecular synthesis: what can it offer? Chemical Science. 9: 3080-3094. PMID 29780455 DOI: 10.1039/C7Sc05371A  0.377
2018 Cao Q, Howard JL, Crawford DE, James SL, Browne DL. Translating solid state organic synthesis from a mixer mill to a continuous twin screw extruder Green Chemistry. 20: 4443-4447. DOI: 10.1039/C8Gc02036A  0.365
2018 Schotten C, Howard JL, Jenkins RL, Codina A, Browne DL. A continuous flow-batch hybrid reactor for commodity chemical synthesis enabled by inline NMR and temperature monitoring Tetrahedron. 74: 5503-5509. DOI: 10.1016/J.Tet.2018.05.070  0.391
2017 Howard JL, Nicholson W, Sagatov Y, Browne DL. One-pot multistep mechanochemical synthesis of fluorinated pyrazolones. Beilstein Journal of Organic Chemistry. 13: 1950-1956. PMID 29062413 DOI: 10.3762/Bjoc.13.189  0.44
2017 Pope SJ, Groves L, Schotten C, Beames J, Platts J, Browne D, Coles S, Horton P. From Ligand to Phosphor: Rapid, Machine-Assisted Syntheses of Substituted Iridium(III)-Pyrazolate Complexes with Tuneable Luminescence. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 28543913 DOI: 10.1002/Chem.201701551  0.322
2017 Howard JL, Schotten C, Browne DL. Continuous flow synthesis of antimalarials: opportunities for distributed autonomous chemical manufacturing Reaction Chemistry and Engineering. 2: 281-287. DOI: 10.1039/C7Re00034K  0.335
2017 Howard JL, Sagatov Y, Repusseau L, Schotten C, Browne DL. Controlling reactivity through liquid assisted grinding: the curious case of mechanochemical fluorination Green Chemistry. 19: 2798-2802. DOI: 10.1039/C6Gc03139K  0.348
2017 Howard JL, Sagatov Y, Browne DL. Mechanochemical electrophilic fluorination of liquid beta-ketoesters Tetrahedron. 74: 3118-3123. DOI: 10.1016/J.Tet.2017.11.066  0.351
2017 Wilkins LC, Howard JL, Burger S, Frentzel-Beyme L, Browne DL, Melen RL. Exploring Multistep Continuous-Flow Hydrosilylation Reactions Catalyzed by Tris(pentafluorophenyl)borane Advanced Synthesis & Catalysis. 359: 2580-2584. DOI: 10.1002/Adsc.201700349  0.464
2016 Poh JS, Browne DL, Ley SV. A multistep continuous flow synthesis machine for the preparation of pyrazoles via a metal-free amine-redox process. Reaction Chemistry & Engineering. 1: 101-105. PMID 27398231 DOI: 10.1039/C5Re00082C  0.521
2016 Howard JL, Schotten C, Alston ST, Browne DL. Preparation of difluoromethylthioethers through difluoromethylation of disulfides using TMS-CF2H. Chemical Communications (Cambridge, England). PMID 27306975 DOI: 10.1039/C6Cc02693A  0.312
2016 Poh JS, García-Ruiz C, Zúñiga A, Meroni F, Blakemore DC, Browne DL, Ley SV. Synthesis of trifluoromethylated isoxazoles and their elaboration through inter- and intra-molecular C-H arylation. Organic & Biomolecular Chemistry. PMID 27225313 DOI: 10.1039/C6Ob00970K  0.518
2016 Schotten C, Aldmairi AH, Sagatov Y, Shepherd M, Browne DL. Protected diazonium salts: A continuous-flow preparation of triazenes including the anticancer compounds dacarbazine and mitozolomide Journal of Flow Chemistry. 6: 218-225. DOI: 10.1556/1846.2016.00025  0.409
2016 Snieckus V, Miranzadeh M, Poh J-, García-Ruiz C, Zúñiga A, Meroni F, Blakemore DC, Browne DL, Ley SV. Synthesis of Trifluoromethylated Isoxazoles by [2+3] Cycloaddition Synfacts. 12: 900-900. DOI: 10.1055/S-0035-1562575  0.541
2015 Schotten C, Plaza D, Manzini S, Nolan SP, Ley SV, Browne DL, Lapkin A. Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride. Acs Sustainable Chemistry & Engineering. 3: 1453-1459. PMID 26322250 DOI: 10.1021/Acssuschemeng.5B00397  0.492
2015 Schotten C, Plaza D, Manzini S, Nolan SP, Ley SV, Browne DL, Lapkin A. Continuous Flow Metathesis for Direct Valorization of Food Waste: An Example of Cocoa Butter Triglyceride Acs Sustainable Chemistry and Engineering. 3: 1453-1459. DOI: 10.1021/acssuschemeng.5b00397  0.355
2015 Deadman BJ, Browne DL, Baxendale IR, Ley SV. Back pressure regulation of slurry-forming reactions in continuous flow Chemical Engineering and Technology. 38: 259-264. DOI: 10.1002/Ceat.201400445  0.502
2014 Kabeshov MA, Musio B, Murray PR, Browne DL, Ley SV. Expedient preparation of nazlinine and a small library of indole alkaloids using flow electrochemistry as an enabling technology. Organic Letters. 16: 4618-21. PMID 25147957 DOI: 10.1021/Ol502201D  0.502
2014 Browne DL. The trifluoromethylating Sandmeyer reaction: a method for transforming C-N into C-CF(3). Angewandte Chemie (International Ed. in English). 53: 1482-4. PMID 24376150 DOI: 10.1002/Anie.201308997  0.37
2014 Newby JA, Huck L, Blaylock DW, Witt PM, Ley SV, Browne DL. Investigation of a lithium-halogen exchange flow process for the preparation of boronates by using a cryo-flow reactor. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 263-71. PMID 24339222 DOI: 10.1002/Chem.201303736  0.547
2014 Newby JA, Blaylock DW, Witt PM, Turner RM, Heider PL, Harji BH, Browne DL, Ley SV. Reconfiguration of a continuous flow platform for extended operation: Application to a cryogenic fluorine-directed ortho-lithiation reaction Organic Process Research and Development. 18: 1221-1228. DOI: 10.1021/Op500221S  0.53
2014 Newby JA, Blaylock DW, Witt PM, Pastre JC, Zacharova MK, Ley SV, Browne DL. Design and application of a low-temperature continuous flow chemistry platform Organic Process Research and Development. 18: 1211-1220. DOI: 10.1021/Op500213J  0.526
2013 Pastre JC, Browne DL, Ley SV. Flow chemistry syntheses of natural products. Chemical Society Reviews. 42: 8849-69. PMID 23999700 DOI: 10.1039/C3Cs60246J  0.489
2013 Ley SV, Ingham RJ, O'Brien M, Browne DL. Camera-enabled techniques for organic synthesis. Beilstein Journal of Organic Chemistry. 9: 1051-72. PMID 23766820 DOI: 10.3762/Bjoc.9.118  0.473
2013 Nakayama K, Browne DL, Baxendale IR, Ley SV. Studies of a diastereoselective electrophilic fluorination reaction employing a cryo-flow reactor Synlett. 24: 1298-1302. DOI: 10.1055/S-0033-1338455  0.53
2013 Murray PRD, Browne DL, Pastre JC, Butters C, Guthrie D, Ley SV. Continuous flow-processing of organometallic reagents using an advanced peristaltic pumping system and the telescoped flow synthesis of (E/Z)-tamoxifen Organic Process Research and Development. 17: 1192-1208. DOI: 10.1021/Op4001548  0.55
2013 Pastre JC, Browne DL, O'Brien M, Ley SV. Scaling up of continuous flow processes with gases using a tube-in-tube reactor: Inline titrations and fanetizole synthesis with ammonia Organic Process Research and Development. 17: 1183-1191. DOI: 10.1021/Op400152R  0.499
2013 Browne DL, Harji BH, Ley SV. Continuous Cold without Cryogenic Consumables: Development of a Convenient Laboratory Tool for Low-Temperature Flow Processes Chemical Engineering and Technology. 36: 959-967. DOI: 10.1002/Ceat.201200581  0.534
2012 Tran G, Meier R, Harris L, Browne DL, Ley SV. Synthesis and use of a trifluoromethylated azomethine ylide precursor. The Journal of Organic Chemistry. 77: 11071-8. PMID 23176732 DOI: 10.1021/Jo302052M  0.485
2012 O'Brien M, Koos P, Browne DL, Ley SV. A prototype continuous-flow liquid-liquid extraction system using open-source technology. Organic & Biomolecular Chemistry. 10: 7031-6. PMID 22858870 DOI: 10.1039/C2Ob25912E  0.436
2012 Browne DL, Wright S, Deadman BJ, Dunnage S, Baxendale IR, Turner RM, Ley SV. Continuous flow reaction monitoring using an on-line miniature mass spectrometer. Rapid Communications in Mass Spectrometry : Rcm. 26: 1999-2010. PMID 22847699 DOI: 10.1002/Rcm.6312  0.506
2012 Cranwell PB, O'Brien M, Browne DL, Koos P, Polyzos A, Peña-López M, Ley SV. Flow synthesis using gaseous ammonia in a Teflon AF-2400 tube-in-tube reactor: Paal-Knorr pyrrole formation and gas concentration measurement by inline flow titration. Organic & Biomolecular Chemistry. 10: 5774-9. PMID 22532036 DOI: 10.1039/C2Ob25407G  0.704
2012 Koos P, Browne DL, Ley SV. Continuous stream processing: A prototype magnetic field induced flow mixer Green Processing and Synthesis. 1: 11-18. DOI: 10.1515/Greenps-2011-0501  0.449
2012 Ley SV, Browne DL. Total Synthesis and Reassignment of 11-Gorgiacerol and 11-Epigorgiacerol Synfacts. 8: 929-929. DOI: 10.1055/S-0032-1317037  0.517
2012 Ley SV, Browne DL. Total Synthesis of (±)−Agelastatin A Synfacts. 8: 946-946. DOI: 10.1055/S-0032-1317036  0.418
2012 Ley SV, Browne DL. Synthesis of (–)-Mersicarpine Synfacts. 8: 827-827. DOI: 10.1055/S-0032-1316647  0.491
2012 Ley SV, Browne DL. Synthesis of ent-Palmyrolide A Synfacts. 8: 708-708. DOI: 10.1055/S-0032-1289839  0.526
2012 Ley SV, Browne DL. Synthesis of (–)-Hanishin, (–)-Longamide B and (–)-Longamide B Methyl Ester Synfacts. 8: 696-696. DOI: 10.1055/S-0032-1289838  0.403
2012 Ley SV, Browne DL. Synthesis of (S)-Bisoranjidiol Synfacts. 8: 588-588. DOI: 10.1055/S-0031-1291049  0.462
2012 Browne D, O'Brien M, Koos P, Cranwell PB, Polyzos A, Ley SV. Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: Synthesis of thioureas and in-line titrations Synlett. 23: 1402-1406. DOI: 10.1055/S-0031-1290963  0.706
2012 Ley SV, Browne DL. Formal Synthesis of Aspergillide B Synfacts. 8: 471-471. DOI: 10.1055/S-0031-1290898  0.441
2012 Ley SV, Browne DL. Enantioselective Synthesis of Pumiliotoxin C and trans-195A Synfacts. 8: 469-469. DOI: 10.1055/S-0031-1290897  0.435
2012 Ley SV, Browne DL. Total Synthesis of (±)-γ-Lycorane Synfacts. 8: 131-131. DOI: 10.1055/S-0031-1290185  0.418
2012 Ley SV, Browne DL. Total Synthesis and Structural Revision of the Piperarborenines Synfacts. 8: 119-119. DOI: 10.1055/S-0031-1290180  0.456
2012 Ley SV, Browne DL. Synthesis of (±)-Hamayne Synfacts. 8: 13-13. DOI: 10.1055/S-0031-1289923  0.414
2012 Browne DL, O'Brien M, Koos P, Cranwell PB, Polyzos A, Ley SV. ChemInform Abstract: Continuous Flow Processing of Gaseous Ammonia Using a Teflon AF-2400 Tube-in-Tube Reactor: Synthesis of Thioureas and In-Line Titrations. Cheminform. 43: no-no. DOI: 10.1002/chin.201238069  0.666
2011 Browne DL, Baumann M, Harji BH, Baxendale IR, Ley SV. A new enabling technology for convenient laboratory scale continuous flow processing at low temperatures. Organic Letters. 13: 3312-5. PMID 21615126 DOI: 10.1021/Ol2010006  0.527
2011 Browne DL, Deadman BJ, Ashe R, Baxendale IR, Ley SV. Continuous flow processing of slurries: Evaluation of an agitated cell reactor Organic Process Research and Development. 15: 693-697. DOI: 10.1021/Op2000223  0.505
2011 Browne DL, Baxendale IR, Ley SV. Piecing together the puzzle: Understanding a mild, metal free reduction method for the large scale synthesis of hydrazines Tetrahedron. 67: 10296-10303. DOI: 10.1016/J.Tet.2011.09.146  0.47
2010 Crossley JA, Browne DL. An alkynyliodide cycloaddition strategy for the construction of iodoisoxazoles. The Journal of Organic Chemistry. 75: 5414-6. PMID 20608670 DOI: 10.1021/Jo1011174  0.345
2010 Browne DL, Taylor JB, Plant A, Harrity JP. Alkyne [3 + 2] cycloadditions of iodosydnones toward functionalized 1,3,5-trisubstituted pyrazoles. The Journal of Organic Chemistry. 75: 984-7. PMID 20030356 DOI: 10.1021/Jo902514V  0.626
2010 Crossley JA, Kirkham JD, Browne DL, Harrity JPA. On the use of 2-(trimethylsilyl)iodobenzene as a benzyne precursor Tetrahedron Letters. 51: 6608-6610. DOI: 10.1016/J.Tetlet.2010.10.052  0.368
2010 Crossley JA, Browne DL. Cycloaddition of benzynes and nitrile oxides: synthesis of benzisoxazoles Tetrahedron Letters. 51: 2271-2273. DOI: 10.1016/J.Tetlet.2010.02.103  0.403
2010 Browne DL, Harrity JPA. Recent developments in the chemistry of sydnones Tetrahedron. 66: 553-568. DOI: 10.1016/J.Tet.2009.10.085  0.392
2009 Foster RS, Huang J, Vivat JF, Browne DL, Harrity JP. A divergent strategy to the withasomnines. Organic & Biomolecular Chemistry. 7: 4052-6. PMID 19763310 DOI: 10.1039/B910632D  0.717
2009 Browne DL, Vivat JF, Plant A, Gomez-Bengoa E, Harrity JP. Investigation of the scope and regiochemistry of alkynylboronate cycloadditions with sydnones. Journal of the American Chemical Society. 131: 7762-9. PMID 19449876 DOI: 10.1021/Ja902460N  0.683
2009 Browne DL, Taylor JB, Plant A, Harrity JP. Cross coupling of bromo sydnones: development of a flexible route toward functionalized pyrazoles. The Journal of Organic Chemistry. 74: 396-400. PMID 19053608 DOI: 10.1021/Jo802240E  0.64
2008 Browne DL, Helm MD, Plant A, Harrity JPA. [2+3]-Cycloaddition Route to Pyrazole Boronic Esters from Sydnones and Alkynylboronates Synfacts. 2008: 137-137. DOI: 10.1055/S-2007-992465  0.371
2008 Delaney PM, Browne DL, Adams H, Plant A, Harrity JPA. A 2-pyrone cycloaddition route to functionalised aromatic boronic esters Tetrahedron. 64: 866-873. DOI: 10.1016/J.Tet.2007.08.118  0.39
2007 Browne DL, Helm MD, Plant A, Harrity JP. A sydnone cycloaddition route to pyrazole boronic esters. Angewandte Chemie (International Ed. in English). 46: 8656-8. PMID 17918173 DOI: 10.1002/Anie.200703767  0.652
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