Alan Verkman - Publications

Affiliations: 
Harvard Medical School, Boston, MA, United States 

209 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Smith AJ, Akdemir G, Wadhwa M, Song D, Verkman AS. Application of fluorescent dextrans to the brain surface under constant pressure reveals AQP4-independent solute uptake. The Journal of General Physiology. 153. PMID 34128962 DOI: 10.1085/jgp.202112898  0.32
2020 Nalle SC, Barreira da Silva R, Zhang H, Decker M, Chalouni C, Xu M, Posthuma G, de Mazière A, Klumperman J, Baz Morelli A, Fleire SJ, Verkman AS, Trombetta ES, Albert ML, Mellman I. Aquaporin-3 regulates endosome-to-cytosol transfer via lipid peroxidation for cross presentation. Plos One. 15: e0238484. PMID 33232321 DOI: 10.1371/journal.pone.0238484  0.36
2020 Pasricha ND, Smith AJ, Levin MH, Schallhorn JM, Verkman AS. Ocular Surface Potential Difference Measured in Human Subjects to Study Ocular Surface Ion Transport. Translational Vision Science & Technology. 9: 20. PMID 33117611 DOI: 10.1167/tvst.9.11.20  0.32
2019 Smith AJ, Verkman AS. CrossTalk opposing view: Going against the flow: interstitial solute transport in brain is diffusive and aquaporin-4 independent. The Journal of Physiology. PMID 31389038 DOI: 10.1113/JP277636  0.32
2019 Smith AJ, Verkman AS. Rebuttal from Alex J. Smith and Alan S. Verkman. The Journal of Physiology. PMID 31389015 DOI: 10.1113/JP278461  0.32
2019 Duan T, Smith AJ, Verkman AS. Complement-independent bystander injury in AQP4-IgG seropositive neuromyelitis optica produced by antibody-dependent cellular cytotoxicity. Acta Neuropathologica Communications. 7: 112. PMID 31296268 DOI: 10.1186/s40478-019-0766-7  0.32
2019 Smith AJ, Duan T, Verkman AS. Aquaporin-4 reduces neuropathology in a mouse model of Alzheimer's disease by remodeling peri-plaque astrocyte structure. Acta Neuropathologica Communications. 7: 74. PMID 31068220 DOI: 10.1186/s40478-019-0728-0  0.32
2018 Yao X, Adams MS, Jones PD, Diederich CJ, Verkman AS. Noninvasive, Targeted Creation of Neuromyelitis Optica Pathology in AQP4-IgG Seropositive Rats by Pulsed Focused Ultrasound. Journal of Neuropathology and Experimental Neurology. PMID 30500945 DOI: 10.1093/Jnen/Nly107  0.32
2018 Duan T, Smith AJ, Verkman AS. Complement-dependent bystander injury to neurons in AQP4-IgG seropositive neuromyelitis optica. Journal of Neuroinflammation. 15: 294. PMID 30348195 DOI: 10.1186/s12974-018-1333-z  0.32
2018 Jin BJ, Lee S, Verkman AS. Hollow Micropillar Array Method for High-Capacity Drug Screening on Filter-Grown Epithelial Cells. Analytical Chemistry. PMID 29779372 DOI: 10.1021/acs.analchem.8b01554  0.32
2018 Verkman AS, Yao X, Smith AJ. The evolving mystery of why skeletal muscle is spared in seropositive neuromyelitis optica. Journal of Cellular and Molecular Medicine. PMID 29363875 DOI: 10.1111/jcmm.13482  0.32
2017 Smith AJ, Verkman AS. The "glymphatic" mechanism for solute clearance in Alzheimer's disease: game changer or unproven speculation? Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 29101220 DOI: 10.1096/fj.201700999  0.32
2017 Verkman AS, Smith AJ, Phuan PW, Tradtrantip L, Anderson MO. The aquaporin-4 water channel as a potential drug target in neurological disorders. Expert Opinion On Therapeutic Targets. PMID 29072508 DOI: 10.1080/14728222.2017.1398236  0.32
2017 Smith AJ, Yao X, Dix JA, Jin BJ, Verkman AS. Test of the 'glymphatic' hypothesis demonstrates diffusive and aquaporin-4-independent solute transport in rodent brain parenchyma. Elife. 6. PMID 28826498 DOI: 10.7554/eLife.27679  1
2017 Yao X, Verkman AS. Complement regulator CD59 prevents peripheral organ injury in rats made seropositive for neuromyelitis optica immunoglobulin G. Acta Neuropathologica Communications. 5: 57. PMID 28750658 DOI: 10.1186/s40478-017-0462-4  0.32
2017 Tradtrantip L, Yao X, Su T, Smith AJ, Verkman AS. Bystander mechanism for complement-initiated early oligodendrocyte injury in neuromyelitis optica. Acta Neuropathologica. PMID 28567523 DOI: 10.1007/s00401-017-1734-6  0.32
2017 Tradtrantip L, Jin BJ, Yao X, Anderson MO, Verkman AS. Aquaporin-Targeted Therapeutics: State-of-the-Field. Advances in Experimental Medicine and Biology. 969: 239-250. PMID 28258578 DOI: 10.1007/978-94-024-1057-0_16  0.32
2017 Yao X, Verkman AS. Marked central nervous system pathology in CD59 knockout rats following passive transfer of Neuromyelitis optica immunoglobulin G. Acta Neuropathologica Communications. 5: 15. PMID 28212662 DOI: 10.1186/s40478-017-0417-9  0.32
2017 Jin BJ, Verkman AS. Microfluidic platform for rapid measurement of transepithelial water transport. Lab On a Chip. PMID 28184395 DOI: 10.1039/c6lc01456a  0.32
2016 Verkman AS, Tradtrantip L, Smith AJ, Yao X. Aquaporin Water Channels and Hydrocephalus. Pediatric Neurosurgery. PMID 27978530 DOI: 10.1159/000452168  0.32
2016 Jin BJ, Smith AJ, Verkman AS. Spatial model of convective solute transport in brain extracellular space does not support a "glymphatic" mechanism. The Journal of General Physiology. PMID 27836940 DOI: 10.1085/jgp.201611684  0.32
2016 Yao X, Su T, Verkman AS. Clobetasol promotes remyelination in a mouse model of neuromyelitis optica. Acta Neuropathologica Communications. 4: 42. PMID 27117475 DOI: 10.1186/s40478-016-0309-4  0.32
2016 Esteva-Font C, Jin BJ, Lee S, Phuan PW, Anderson MO, Verkman AS. Experimental evaluation of proposed small-molecule inhibitors of water channel aquaporin-1. Molecular Pharmacology. PMID 26993802 DOI: 10.1124/Mol.116.103929  1
2016 Haggie PM, Phuan PW, Tan JA, Zlock L, Finkbeiner WE, Verkman AS. Inhibitors of pendrin anion exchange identified in a small molecule screen increase airway surface liquid volume in cystic fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. PMID 26932931 DOI: 10.1096/fj.201600223R  1
2015 Smith AJ, Verkman AS. Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections. Biophysical Journal. 109: 2511-22. PMID 26682810 DOI: 10.1016/j.bpj.2015.10.047  0.32
2015 Phuan PW, Veit G, Tan JA, Finkbeiner WE, Lukacs GL, Verkman AS. Potentiators of Defective ΔF508-CFTR Gating that Do Not Interfere with Corrector Action. Molecular Pharmacology. 88: 791-9. PMID 26245207 DOI: 10.1124/mol.115.099689  1
2015 Kim Y, Anderson MO, Park J, Lee MG, Namkung W, Verkman AS. Benzopyrimido-pyrrolo-oxazine-dione (R)-BPO-27 Inhibits CFTR Chloride Channel Gating by Competition with ATP. Molecular Pharmacology. PMID 26174774 DOI: 10.1124/Mol.115.098368  1
2015 Jin BJ, Esteva-Font C, Verkman AS. Droplet-based microfluidic platform for measurement of rapid erythrocyte water transport. Lab On a Chip. 15: 3380-90. PMID 26159099 DOI: 10.1039/c5lc00688k  0.32
2015 Thiagarajah JR, Donowitz M, Verkman AS. Secretory diarrhoea: mechanisms and emerging therapies. Nature Reviews. Gastroenterology & Hepatology. 12: 446-57. PMID 26122478 DOI: 10.1038/Nrgastro.2015.111  1
2015 Hara-Chikuma M, Satooka H, Watanabe S, Honda T, Miyachi Y, Watanabe T, Verkman AS. Aquaporin-3-mediated hydrogen peroxide transport is required for NF-κB signalling in keratinocytes and development of psoriasis. Nature Communications. 6: 7454. PMID 26100668 DOI: 10.1038/ncomms8454  1
2015 Cil O, Esteva-Font C, Tas ST, Su T, Lee S, Anderson MO, Ertunc M, Verkman AS. Salt-sparing diuretic action of a water-soluble urea analog inhibitor of urea transporters UT-A and UT-B in rats. Kidney International. PMID 25993324 DOI: 10.1038/Ki.2015.138  1
2015 Smith AJ, Jin BJ, Verkman AS. Muddying the water in brain edema? Trends in Neurosciences. 38: 331-2. PMID 25980601 DOI: 10.1016/j.tins.2015.04.006  0.32
2015 Yao X, Smith AJ, Jin BJ, Zador Z, Manley GT, Verkman AS. Aquaporin-4 regulates the velocity and frequency of cortical spreading depression in mice. Glia. PMID 25944186 DOI: 10.1002/Glia.22853  0.32
2015 Owens GP, Ritchie A, Rossi A, Schaller K, Wemlinger S, Schumann H, Shearer A, Verkman AS, Bennett JL. Mutagenesis of the aquaporin 4 extracellular domains defines restricted binding patterns of pathogenic neuromyelitis optica IgG. The Journal of Biological Chemistry. 290: 12123-34. PMID 25792738 DOI: 10.1074/jbc.M115.647149  1
2015 Yao X, Uchida K, Papadopoulos MC, Zador Z, Manley GT, Verkman AS. Mildly Reduced Brain Swelling and Improved Neurological Outcome in Aquaporin-4 Knockout Mice Following Controlled Cortical Impact Brain Injury. Journal of Neurotrauma. PMID 25790314 DOI: 10.1089/Neu.2014.3675  0.32
2015 Esteva-Font C, Phuan PW, Lee S, Su T, Anderson MO, Verkman AS. Structure-activity analysis of thiourea analogs as inhibitors of UT-A and UT-B urea transporters. Biochimica Et Biophysica Acta. 1848: 1075-80. PMID 25613743 DOI: 10.1016/J.Bbamem.2015.01.004  1
2015 Wang W, Li F, Sun Y, Lei L, Zhou H, Lei T, Xia Y, Verkman AS, Yang B. Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1551-63. PMID 25573755 DOI: 10.1096/Fj.14-260828  1
2015 Esteva-Font C, Anderson MO, Verkman AS. Urea transporter proteins as targets for small-molecule diuretics. Nature Reviews. Nephrology. 11: 113-23. PMID 25488859 DOI: 10.1038/Nrneph.2014.219  1
2015 Yao X, Derugin N, Manley GT, Verkman AS. Reduced brain edema and infarct volume in aquaporin-4 deficient mice after transient focal cerebral ischemia. Neuroscience Letters. 584: 368-72. PMID 25449874 DOI: 10.1016/J.Neulet.2014.10.040  0.32
2015 Lee S, Esteva-Font C, Phuan PW, Anderson MO, Verkman AS. Discovery, synthesis and structure-activity analysis of symmetrical 2,7-disubstituted fluorenones as urea transporter inhibitors Medchemcomm. 6: 1278-1284. DOI: 10.1039/c5md00198f  1
2015 Cil O, Phuan PW, Lee S, Tan J, Haggie PM, Levin MH, Sun L, Thiagarajah JR, Ma T, Verkman AS. CFTR Activator Increases Intestinal Fluid Secretion and Normalizes Stool Output in a Mouse Model of Constipation Cmgh Cellular and Molecular Gastroenterology and Hepatology. DOI: 10.1016/j.jcmgh.2015.12.010  1
2015 Smith AJ, Verkman AS. Superresolution Imaging of Aquaporin-4 Cluster Size in Antibody-Stained Paraffin Brain Sections Biophysical Journal. 109: 2511-2522. DOI: 10.1016/j.bpj.2015.10.047  1
2014 Ye L, Hu B, El-Badri F, Hudson BM, Phuan PW, Verkman AS, Tantillo DJ, Kurth MJ. ΔF508-CFTR correctors: synthesis and evaluation of thiazole-tethered imidazolones, oxazoles, oxadiazoles, and thiadiazoles. Bioorganic & Medicinal Chemistry Letters. 24: 5840-4. PMID 25452003 DOI: 10.1016/J.Bmcl.2014.09.067  1
2014 Verkman AS, Esteva-Font C, Cil O, Anderson MO, Li F, Li M, Lei T, Ren H, Yang B. Small-molecule inhibitors of urea transporters. Sub-Cellular Biochemistry. 73: 165-77. PMID 25298345 DOI: 10.1007/978-94-017-9343-8_11  1
2014 Coffman KC, Nguyen HH, Phuan PW, Hudson BM, Yu GJ, Bagdasarian AL, Montgomery D, Lodewyk MW, Yang B, Yoo CL, Verkman AS, Tantillo DJ, Kurth MJ. Constrained bithiazoles: small molecule correctors of defective ΔF508-CFTR protein trafficking. Journal of Medicinal Chemistry. 57: 6729-38. PMID 25061695 DOI: 10.1021/Jm5007885  1
2014 Esteva-Font C, Cil O, Phuan PW, Su T, Lee S, Anderson MO, Verkman AS. Diuresis and reduced urinary osmolality in rats produced by small-molecule UT-A-selective urea transport inhibitors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 3878-90. PMID 24843071 DOI: 10.1096/Fj.14-253872  1
2014 Jin BJ, Battula S, Zachos N, Kovbasnjuk O, Fawlke-Abel J, In J, Donowitz M, Verkman AS. Microfluidics platform for measurement of volume changes in immobilized intestinal enteroids. Biomicrofluidics. 8: 024106. PMID 24738013 DOI: 10.1063/1.4870400  1
2014 Ratelade J, Smith AJ, Verkman AS. Human immunoglobulin G reduces the pathogenicity of aquaporin-4 autoantibodies in neuromyelitis optica. Experimental Neurology. 255: 145-53. PMID 24636863 DOI: 10.1016/j.expneurol.2014.03.004  0.32
2014 Verkman AS, Anderson MO, Papadopoulos MC. Aquaporins: important but elusive drug targets. Nature Reviews. Drug Discovery. 13: 259-77. PMID 24625825 DOI: 10.1038/Nrd4226  1
2014 Smith AJ, Jin BJ, Ratelade J, Verkman AS. Aggregation state determines the localization and function of M1- and M23-aquaporin-4 in astrocytes. The Journal of Cell Biology. 204: 559-73. PMID 24515349 DOI: 10.1083/jcb.201308118  0.32
2014 Thiagarajah JR, Ko EA, Tradtrantip L, Donowitz M, Verkman AS. Discovery and development of antisecretory drugs for treating diarrheal diseases. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 204-9. PMID 24316107 DOI: 10.1016/J.Cgh.2013.12.001  1
2014 Blanchard E, Zlock L, Lao A, Mika D, Namkung W, Xie M, Scheitrum C, Gruenert DC, Verkman AS, Finkbeiner WE, Conti M, Richter W. Anchored PDE4 regulates chloride conductance in wild-type and ΔF508-CFTR human airway epithelia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 791-801. PMID 24200884 DOI: 10.1096/Fj.13-240861  1
2014 Katada R, Akdemir G, Asavapanumas N, Ratelade J, Zhang H, Verkman AS. Greatly improved survival and neuroprotection in aquaporin-4-knockout mice following global cerebral ischemia. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 705-14. PMID 24186965 DOI: 10.1096/fj.13-231274  0.36
2014 Singh V, Yang J, Chen TE, Zachos NC, Kovbasnjuk O, Verkman AS, Donowitz M. Translating molecular physiology of intestinal transport into pharmacologic treatment of diarrhea: stimulation of Na+ absorption. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 12: 27-31. PMID 24184676 DOI: 10.1016/J.Cgh.2013.10.020  1
2014 Valentine CD, Zhang H, Phuan PW, Nguyen J, Verkman AS, Haggie PM. Small molecule screen yields inhibitors of Pseudomonas homoserine lactone-induced host responses. Cellular Microbiology. 16: 1-14. PMID 23910799 DOI: 10.1111/Cmi.12176  0.36
2013 Esteva-Font C, Phuan PW, Anderson MO, Verkman AS. A small molecule screen identifies selective inhibitors of urea transporter UT-A. Chemistry & Biology. 20: 1235-44. PMID 24055006 DOI: 10.1016/J.Chembiol.2013.08.005  1
2013 Snyder DS, Tradtrantip L, Battula S, Yao C, Phuan PW, Fettinger JC, Kurth MJ, Verkman AS. ABSOLUTE CONFIGURATION AND BIOLOGICAL PROPERTIES OF ENANTIOMERS OF CFTR INHIBITOR BPO-27. Acs Medicinal Chemistry Letters. 4: 456-459. PMID 23814642 DOI: 10.1021/Ml400069K  1
2013 Jin BJ, Zhang H, Binder DK, Verkman AS. Response to "When can AQP4 assist transporter-mediated K⁺ uptake?". The Journal of General Physiology. 142: 91-2. PMID 23752331 DOI: 10.1085/Jgp.201311010  1
2013 Phuan PW, Zhang H, Asavapanumas N, Leviten M, Rosenthal A, Tradtrantip L, Verkman AS. C1q-targeted monoclonal antibody prevents complement-dependent cytotoxicity and neuropathology in in vitro and mouse models of neuromyelitis optica. Acta Neuropathologica. 125: 829-40. PMID 23677375 DOI: 10.1007/s00401-013-1128-3  0.36
2013 Okiyoneda T, Veit G, Dekkers JF, Bagdany M, Soya N, Xu H, Roldan A, Verkman AS, Kurth M, Simon A, Hegedus T, Beekman JM, Lukacs GL. Mechanism-based corrector combination restores ΔF508-CFTR folding and function. Nature Chemical Biology. 9: 444-54. PMID 23666117 DOI: 10.1038/Nchembio.1253  1
2013 Liu Y, Esteva-Font C, Yao C, Phuan PW, Verkman AS, Anderson MO. 1,1-Difluoroethyl-substituted triazolothienopyrimidines as inhibitors of a human urea transport protein (UT-B): new analogs and binding model. Bioorganic & Medicinal Chemistry Letters. 23: 3338-41. PMID 23597791 DOI: 10.1016/J.Bmcl.2013.03.089  1
2013 Verkman AS, Synder D, Tradtrantip L, Thiagarajah JR, Anderson MO. CFTR inhibitors. Current Pharmaceutical Design. 19: 3529-41. PMID 23331030 DOI: 10.2174/13816128113199990321  1
2013 Jin BJ, Zhang H, Binder DK, Verkman AS. Aquaporin-4-dependent K(+) and water transport modeled in brain extracellular space following neuroexcitation. The Journal of General Physiology. 141: 119-32. PMID 23277478 DOI: 10.1085/Jgp.201210883  1
2013 Rowe SM, Verkman AS. Cystic fibrosis transmembrane regulator correctors and potentiators Cold Spring Harbor Perspectives in Biology. 5. DOI: 10.1101/cshperspect.a009761  1
2012 Saadoun S, Bridges LR, Verkman AS, Papadopoulos MC. Paucity of natural killer and cytotoxic T cells in human neuromyelitis optica lesions Neuroreport. 23: 1044-1047. PMID 23108041 DOI: 10.1097/WNR.0b013e32835ab480  1
2012 Phuan PW, Anderson MO, Tradtrantip L, Zhang H, Tan J, Lam C, Bennett JL, Verkman AS. A small-molecule screen yields idiotype-specific blockers of neuromyelitis optica immunoglobulin G binding to aquaporin-4. The Journal of Biological Chemistry. 287: 36837-44. PMID 22989877 DOI: 10.1074/Jbc.M112.408716  1
2012 Veit G, Bossard F, Goepp J, Verkman AS, Galietta LJ, Hanrahan JW, Lukacs GL. Proinflammatory cytokine secretion is suppressed by TMEM16A or CFTR channel activity in human cystic fibrosis bronchial epithelia. Molecular Biology of the Cell. 23: 4188-202. PMID 22973054 DOI: 10.1091/mbc.E12-06-0424  1
2012 Donald MB, Rodriguez KX, Shay H, Phuan PW, Verkman AS, Kurth MJ. Click-based synthesis of triazolobithiazole ΔF508-CFTR correctors for cystic fibrosis. Bioorganic & Medicinal Chemistry. 20: 5247-53. PMID 22841006 DOI: 10.1016/j.bmc.2012.06.046  1
2012 Kumar S, Namkung W, Verkman AS, Sharma PK. Novel 5-substituted benzyloxy-2-arylbenzofuran-3-carboxylic acids as calcium activated chloride channel inhibitors Bioorganic and Medicinal Chemistry. 20: 4237-4244. PMID 22739085 DOI: 10.1016/j.bmc.2012.05.074  1
2012 Anderson MO, Zhang J, Liu Y, Yao C, Phuan PW, Verkman AS. Nanomolar potency and metabolically stable inhibitors of kidney urea transporter UT-B. Journal of Medicinal Chemistry. 55: 5942-50. PMID 22694147 DOI: 10.1021/Jm300491Y  1
2012 Yao C, Anderson MO, Zhang J, Yang B, Phuan PW, Verkman AS. Triazolothienopyrimidine inhibitors of urea transporter UT-B reduce urine concentration. Journal of the American Society of Nephrology : Jasn. 23: 1210-20. PMID 22491419 DOI: 10.1681/ASN.2011070751  1
2012 Saadoun S, Waters P, MacDonald C, Bell BA, Vincent A, Verkman AS, Papadopoulos MC. Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain. Annals of Neurology. 71: 323-33. PMID 22374891 DOI: 10.1002/ana.22686  1
2012 Tradtrantip L, Zhang H, Anderson MO, Saadoun S, Phuan PW, Papadopoulos MC, Bennett JL, Verkman AS. Small-molecule inhibitors of NMO-IgG binding to aquaporin-4 reduce astrocyte cytotoxicity in neuromyelitis optica. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2197-208. PMID 22319008 DOI: 10.1096/fj.11-201608  1
2012 Davison HR, Solano DM, Phuan PW, Verkman AS, Kurth MJ. Fluorinated ΔF508-CFTR correctors and potentiators for PET imaging. Bioorganic & Medicinal Chemistry Letters. 22: 1602-5. PMID 22281185 DOI: 10.1016/J.Bmcl.2011.12.128  1
2012 Tradtrantip L, Zhang H, Saadoun S, Phuan PW, Lam C, Papadopoulos MC, Bennett JL, Verkman AS. Anti-aquaporin-4 monoclonal antibody blocker therapy for neuromyelitis optica. Annals of Neurology. 71: 314-22. PMID 22271321 DOI: 10.1002/ana.22657  0.36
2012 Verkman AS, Rossi A, Crane JM. Live-cell imaging of aquaporin-4 supramolecular assembly and diffusion. Methods in Enzymology. 504: 341-54. PMID 22264543 DOI: 10.1016/B978-0-12-391857-4.00017-3  1
2012 Knapp JM, Wood AB, Phuan PW, Lodewyk MW, Tantillo DJ, Verkman AS, Kurth MJ. Structure-activity relationships of cyanoquinolines with corrector-potentiator activity in ΔF508 cystic fibrosis transmembrane conductance regulator protein. Journal of Medicinal Chemistry. 55: 1242-51. PMID 22214395 DOI: 10.1021/Jm201372Q  1
2011 Carpenter RD, Verkman AS. Function-Oriented Synthesis of a Didesmethyl Triazacryptand Analogue for Fluorescent Potassium Ion Sensing. European Journal of Organic Chemistry. 2011: 1242-1248. PMID 23914138 DOI: 10.1002/ejoc.201001450  1
2011 Davison HR, Taylor S, Drake C, Phuan PW, Derichs N, Yao C, Jones EF, Sutcliffe J, Verkman AS, Kurth MJ. Functional fluorescently labeled bithiazole ΔF508-CFTR corrector imaged in whole body slices in mice. Bioconjugate Chemistry. 22: 2593-9. PMID 22034937 DOI: 10.1021/Bc2004457  1
2011 Phuan PW, Yang B, Knapp JM, Wood AB, Lukacs GL, Kurth MJ, Verkman AS. Cyanoquinolines with independent corrector and potentiator activities restore ΔPhe508-cystic fibrosis transmembrane conductance regulator chloride channel function in cystic fibrosis. Molecular Pharmacology. 80: 683-93. PMID 21730204 DOI: 10.1124/Mol.111.073056  1
2011 Snyder DS, Tradtrantip L, Yao C, Kurth MJ, Verkman AS. Potent, metabolically stable benzopyrimido-pyrrolo-oxazine-dione (BPO) CFTR inhibitors for polycystic kidney disease. Journal of Medicinal Chemistry. 54: 5468-77. PMID 21707078 DOI: 10.1021/Jm200505E  1
2011 Crane JM, Rossi A, Gupta T, Bennett JL, Verkman AS. Orthogonal array formation by human aquaporin-4: examination of neuromyelitis optica-associated aquaporin-4 polymorphisms. Journal of Neuroimmunology. 236: 93-8. PMID 21621278 DOI: 10.1016/J.Jneuroim.2011.05.001  1
2011 Verkman AS, Ratelade J, Rossi A, Zhang H, Tradtrantip L. Aquaporin-4: orthogonal array assembly, CNS functions, and role in neuromyelitis optica. Acta Pharmacologica Sinica. 32: 702-10. PMID 21552296 DOI: 10.1038/aps.2011.27  0.36
2011 Skucas VA, Mathews IB, Yang J, Cheng Q, Treister A, Duffy AM, Verkman AS, Hempstead BL, Wood MA, Binder DK, Scharfman HE. Impairment of select forms of spatial memory and neurotrophin-dependent synaptic plasticity by deletion of glial aquaporin-4. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 6392-7. PMID 21525279 DOI: 10.1523/Jneurosci.6249-10.2011  1
2011 Rossi A, Crane JM, Verkman AS. Aquaporin-4 Mz isoform: brain expression, supramolecular assembly and neuromyelitis optica antibody binding. Glia. 59: 1056-63. PMID 21491501 DOI: 10.1002/Glia.21177  1
2011 Crane JM, Lam C, Rossi A, Gupta T, Bennett JL, Verkman AS. Binding affinity and specificity of neuromyelitis optica autoantibodies to aquaporin-4 M1/M23 isoforms and orthogonal arrays. The Journal of Biological Chemistry. 286: 16516-24. PMID 21454592 DOI: 10.1074/Jbc.M111.227298  1
2010 Yu GJ, Yang B, Verkman AS, Kurth MJ. Isoxazolopyrimidines as Novel ΔF508-CFTR Correctors. Synlett : Accounts and Rapid Communications in Synthetic Organic Chemistry. 2010: 1063-1066. PMID 23710112 DOI: 10.1055/S-0029-1219781  1
2010 Kimura A, Hsu M, Seldin M, Verkman AS, Scharfman HE, Binder DK. Protective role of aquaporin-4 water channels after contusion spinal cord injury. Annals of Neurology. 67: 794-801. PMID 20517941 DOI: 10.1002/Ana.22023  1
2010 Ye L, Knapp JM, Sangwung P, Fettinger JC, Verkman AS, Kurth MJ. Pyrazolylthiazole as DeltaF508-cystic fibrosis transmembrane conductance regulator correctors with improved hydrophilicity compared to bithiazoles. Journal of Medicinal Chemistry. 53: 3772-81. PMID 20373765 DOI: 10.1021/Jm100235H  1
2010 Carpenter RD, Verkman AS. Synthesis of a sensitive and selective potassium-sensing fluoroionophore. Organic Letters. 12: 1160-3. PMID 20148571 DOI: 10.1021/ol902836c  1
2010 Tajima M, Crane JM, Verkman AS. Aquaporin-4 (AQP4) associations and array dynamics probed by photobleaching and single-molecule analysis of green fluorescent protein-AQP4 chimeras. The Journal of Biological Chemistry. 285: 8163-70. PMID 20071343 DOI: 10.1074/Jbc.M109.093948  1
2010 Saadoun S, Waters P, Bell BA, Vincent A, Verkman AS, Papadopoulos MC. Intra-cerebral injection of neuromyelitis optica immunoglobulin G and human complement produces neuromyelitis optica lesions in mice. Brain : a Journal of Neurology. 133: 349-61. PMID 20047900 DOI: 10.1093/brain/awp309  1
2010 Mills AD, Yoo C, Butler JD, Yang B, Verkman AS, Kurth MJ. Design and synthesis of a hybrid potentiator-corrector agonist of the cystic fibrosis mutant protein DeltaF508-CFTR. Bioorganic & Medicinal Chemistry Letters. 20: 87-91. PMID 19954980 DOI: 10.1016/J.Bmcl.2009.11.020  1
2010 Crane JM, Tajima M, Verkman AS. Live-cell imaging of aquaporin-4 diffusion and interactions in orthogonal arrays of particles. Neuroscience. 168: 892-902. PMID 19699275 DOI: 10.1016/J.Neuroscience.2009.08.034  1
2009 Crane JM, Haggie PM, Verkman AS. QUANTUM DOT SINGLE MOLECULE TRACKING REVEALS A WIDE RANGE OF DIFFUSIVE MOTIONS OF MEMBRANE TRANSPORT PROTEINS. Proceedings of Spie--the International Society For Optical Engineering. 7489. PMID 24386532 DOI: 10.1117/12.816900  1
2009 Crane JM, Verkman AS. Reversible, temperature-dependent supramolecular assembly of aquaporin-4 orthogonal arrays in live cell membranes. Biophysical Journal. 97: 3010-8. PMID 19948131 DOI: 10.1016/J.Bpj.2009.09.017  1
2009 Crane JM, Bennett JL, Verkman AS. Live cell analysis of aquaporin-4 m1/m23 interactions and regulated orthogonal array assembly in glial cells. The Journal of Biological Chemistry. 284: 35850-60. PMID 19843522 DOI: 10.1074/Jbc.M109.071670  1
2009 Song Y, Namkung W, Nielson DW, Lee JW, Finkbeiner WE, Verkman AS. Airway surface liquid depth measured in ex vivo fragments of pig and human trachea: dependence on Na+ and Cl- channel function. American Journal of Physiology. Lung Cellular and Molecular Physiology. 297: L1131-40. PMID 19820035 DOI: 10.1152/ajplung.00085.2009  1
2009 Tradtrantip L, Sonawane ND, Wan N, Verkman AS. Nanomolar potency pyrimido-pyrrolo-quinoxalinedione CFTR inhibitor reduces cyst size in a polycystic kidney disease model Journal of Medicinal Chemistry. 52: 6447-6455. PMID 19785436 DOI: 10.1021/jm9009873  1
2009 Li L, Zhang H, Verkman A. Greatly attenuated experimental autoimmune encephalomyelitis in aquaporin-4 knockout mice. Bmc Neuroscience. 10: 94-94. PMID 19660138 DOI: 10.1186/1471-2202-10-94  0.36
2009 Namkung W, Song Y, Mills AD, Padmawar P, Finkbeiner WE, Verkman AS. In situ measurement of airway surface liquid [K+] using a ratioable K+-sensitive fluorescent dye. The Journal of Biological Chemistry. 284: 15916-26. PMID 19364771 DOI: 10.1074/jbc.M808021200  1
2009 Magzoub M, Zhang H, Dix JA, Verkman AS. Extracellular space volume measured by two-color pulsed dye infusion with microfiberoptic fluorescence photodetection Biophysical Journal. 96: 2382-2390. PMID 19289063 DOI: 10.1016/j.bpj.2008.12.3916  1
2009 Crane JM, Verkman AS. Determinants of aquaporin-4 assembly in orthogonal arrays revealed by live-cell single-molecule fluorescence imaging. Journal of Cell Science. 122: 813-21. PMID 19240114 DOI: 10.1242/Jcs.042341  1
2008 Yu GJ, Yoo CL, Yang B, Lodewyk MW, Meng L, El-Idreesy TT, Fettinger JC, Tantillo DJ, Verkman AS, Kurth MJ. Potent s-cis-locked bithiazole correctors of DeltaF508 cystic fibrosis transmembrane conductance regulator cellular processing for cystic fibrosis therapy. Journal of Medicinal Chemistry. 51: 6044-54. PMID 18788728 DOI: 10.1021/Jm800533C  1
2008 Dix JA, Verkman AS. Crowding effects on diffusion in solutions and cells Annual Review of Biophysics. 37: 247-263. PMID 18573081 DOI: 10.1146/annurev.biophys.37.032807.125824  1
2008 Namkung W, Padmawar P, Mills AD, Verkman AS. Cell-based fluorescence screen for K+ channels and transporters using an extracellular triazacryptand-based K+ sensor. Journal of the American Chemical Society. 130: 7794-5. PMID 18512924 DOI: 10.1021/ja8014499  1
2008 Lu DC, Zhang H, Zador Z, Verkman AS. Impaired olfaction in mice lacking aquaporin-4 water channels. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 22: 3216-23. PMID 18511552 DOI: 10.1096/fj.07-104836  0.36
2008 Crane JM, Van Hoek AN, Skach WR, Verkman AS. Aquaporin-4 dynamics in orthogonal arrays in live cells visualized by quantum dot single particle tracking. Molecular Biology of the Cell. 19: 3369-78. PMID 18495865 DOI: 10.1091/Mbc.E08-03-0322  1
2008 Yoo CL, Yu GJ, Yang B, Robins LI, Verkman AS, Kurth MJ. 4'-Methyl-4,5'-bithiazole-based correctors of defective delta F508-CFTR cellular processing. Bioorganic & Medicinal Chemistry Letters. 18: 2610-4. PMID 18394886 DOI: 10.1016/J.Bmcl.2008.03.037  1
2008 Saadoun S, Bell BA, Verkman AS, Papadopoulos MC. Greatly improved neurological outcome after spinal cord compression injury in AQP4-deficient mice. Brain : a Journal of Neurology. 131: 1087-98. PMID 18267965 DOI: 10.1093/brain/awn014  1
2008 De La Fuente R, Namkung W, Mills A, Verkman AS. Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel. Molecular Pharmacology. 73: 758-68. PMID 18083779 DOI: 10.1124/mol.107.043208  1
2008 Crane JM, Verkman AS. Long-range nonanomalous diffusion of quantum dot-labeled aquaporin-1 water channels in the cell plasma membrane. Biophysical Journal. 94: 702-13. PMID 17890385 DOI: 10.1529/Biophysj.107.115121  1
2007 Yangthara B, Mills A, Chatsudthipong V, Tradtrantip L, Verkman AS. Small-molecule vasopressin-2 receptor antagonist identified by a g-protein coupled receptor "pathway" screen. Molecular Pharmacology. 72: 86-94. PMID 17435162 DOI: 10.1124/mol.107.034496  1
2007 Perez A, Issler AC, Cotton CU, Kelley TJ, Verkman AS, Davis PB. CFTR inhibition mimics the cystic fibrosis inflammatory profile. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L383-95. PMID 16920886 DOI: 10.1152/Ajplung.00403.2005  1
2006 Levin MH, Sullivan S, Nielson D, Yang B, Finkbeiner WE, Verkman AS. Hypertonic saline therapy in cystic fibrosis: Evidence against the proposed mechanism involving aquaporins. The Journal of Biological Chemistry. 281: 25803-12. PMID 16829520 DOI: 10.1074/Jbc.M604332200  1
2006 Ripoche P, Goossens D, Devuyst O, Gane P, Colin Y, Verkman AS, Cartron JP. Role of RhAG and AQP1 in NH3 and CO2 gas transport in red cell ghosts: a stopped-flow analysis Transfusion Clinique Et Biologique. 13: 117-122. PMID 16574458 DOI: 10.1016/j.tracli.2006.03.004  1
2006 Verkman AS, Binder DK, Bloch O, Auguste K, Papadopoulos MC. Three distinct roles of aquaporin-4 in brain function revealed by knockout mice. Biochimica Et Biophysica Acta. 1758: 1085-93. PMID 16564496 DOI: 10.1016/J.Bbamem.2006.02.018  1
2006 Thiagarajah JR, Kim JK, Magzoub M, Verkman AS. Slowed diffusion in tumors revealed by microfiberoptic epifluorescence photobleaching. Nature Methods. 3: 275-80. PMID 16554832 DOI: 10.1038/nmeth863  0.36
2006 Dix JA, Hom EF, Verkman AS. Fluorescence correlation spectroscopy simulations of photophysical phenomena and molecular interactions: a molecular dynamics/monte carlo approach. The Journal of Physical Chemistry. B. 110: 1896-906. PMID 16471761 DOI: 10.1021/jp055840k  1
2006 Binder DK, Yao X, Zador Z, Sick TJ, Verkman AS, Manley GT. Increased seizure duration and slowed potassium kinetics in mice lacking aquaporin-4 water channels. Glia. 53: 631-6. PMID 16470808 DOI: 10.1002/Glia.20318  1
2006 Suen YF, Robins L, Yang B, Verkman AS, Nantz MH, Kurth MJ. Sulfamoyl-4-oxoquinoline-3-carboxamides: novel potentiators of defective DeltaF508-cystic fibrosis transmembrane conductance regulator chloride channel gating. Bioorganic & Medicinal Chemistry Letters. 16: 537-40. PMID 16288863 DOI: 10.1016/J.Bmcl.2005.10.050  1
2006 Song Y, Salinas D, Nielson DW, Verkman AS. Hyperacidity of secreted fluid from submucosal glands in early cystic fibrosis. American Journal of Physiology. Cell Physiology. 290: C741-9. PMID 16207791 DOI: 10.1152/Ajpcell.00379.2005  1
2006 Magzoub M, Padmawar P, Dix JA, Verkman AS. Millisecond association kinetics of K+ with triazacryptand-based K+ indicators measured by fluorescence correlation spectroscopy Journal of Physical Chemistry B. 110: 21216-21221. DOI: 10.1021/jp0633392  1
2005 Padmawar P, Yao X, Bloch O, Manley GT, Verkman AS. K + waves in brain cortex visualized using a long-wavelength K + -sensing fluorescent indicator Nature Methods. 2: 825-827. PMID 16278651 DOI: 10.1038/Nmeth801  0.36
2005 Sohara E, Rai T, Miyazaki JI, Verkman AS, Sasaki S, Uchida S. Defective water and glycerol transport in the proximal tubules of AQP7 knockout mice American Journal of Physiology - Renal Physiology. 289. PMID 15998844 DOI: 10.1152/ajprenal.00133.2005  1
2005 Hara-Chikuma M, Wang Y, Guggino SE, Guggino WB, Verkman AS. Impaired acidification in early endosomes of ClC-5 deficient proximal tubule. Biochemical and Biophysical Research Communications. 329: 941-6. PMID 15752747 DOI: 10.1016/J.Bbrc.2005.02.060  1
2005 Pedemonte N, Sonawane ND, Taddei A, Hu J, Zegarra-Moran O, Suen YF, Robins LI, Dicus CW, Willenbring D, Nantz MH, Kurth MJ, Galietta LJ, Verkman AS. Phenylglycine and sulfonamide correctors of defective delta F508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating. Molecular Pharmacology. 67: 1797-807. PMID 15722457 DOI: 10.1124/Mol.105.010959  1
2005 Salinas D, Haggie PM, Thiagarajah JR, Song Y, Rosbe K, Finkbeiner WE, Nielson DW, Verkman AS. Submucosal gland dysfunction as a primary defect in cystic fibrosis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 431-3. PMID 15596485 DOI: 10.1096/Fj.04-2879Fje  1
2004 Salinas DB, Pedemonte N, Muanprasat C, Finkbeiner WF, Nielson DW, Verkman AS. CFTR involvement in nasal potential differences in mice and pigs studied using a thiazolidinone CFTR inhibitor. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L936-43. PMID 15246976 DOI: 10.1152/Ajplung.00354.2003  1
2004 Kuang K, Yiming M, Wen Q, Li Y, Ma L, Iserovich P, Verkman AS, Fischbarg J. Fluid transport across cultured layers of corneal endothelium from aquaporin-1 null mice. Experimental Eye Research. 78: 791-8. PMID 15037113 DOI: 10.1016/j.exer.2003.11.017  1
2003 Sonawane ND, Szoka FC, Verkman AS. Chloride accumulation and swelling in endosomes enhances DNA transfer by polyamine-DNA polyplexes. The Journal of Biological Chemistry. 278: 44826-31. PMID 12944394 DOI: 10.1074/jbc.M308643200  1
2003 Springsteel MF, Galietta LJ, Ma T, By K, Berger GO, Yang H, Dicus CW, Choung W, Quan C, Shelat AA, Guy RK, Verkman AS, Kurth MJ, Nantz MH. Benzoflavone activators of the cystic fibrosis transmembrane conductance regulator: towards a pharmacophore model for the nucleotide-binding domain. Bioorganic & Medicinal Chemistry. 11: 4113-20. PMID 12927873 DOI: 10.1016/S0968-0896(03)00435-8  1
2003 Sammelson RE, Ma T, Galietta LJ, Verkman AS, Kurth MJ. 3-(2-Benzyloxyphenyl)isoxazoles and isoxazolines: synthesis and evaluation as CFTR activators. Bioorganic & Medicinal Chemistry Letters. 13: 2509-12. PMID 12852954 DOI: 10.1016/S0960-894X(03)00482-7  1
2003 Yang H, Shelat AA, Guy RK, Gopinath VS, Ma T, Du K, Lukacs GL, Taddei A, Folli C, Pedemonte N, Galietta LJ, Verkman AS. Nanomolar affinity small molecule correctors of defective Delta F508-CFTR chloride channel gating. The Journal of Biological Chemistry. 278: 35079-85. PMID 12832418 DOI: 10.1074/jbc.M303098200  1
2003 Caci E, Folli C, Zegarra-Moran O, Ma T, Springsteel MF, Sammelson RE, Nantz MH, Kurth MJ, Verkman AS, Galietta LJ. CFTR activation in human bronchial epithelial cells by novel benzoflavone and benzimidazolone compounds. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L180-8. PMID 12651632 DOI: 10.1152/Ajplung.00351.2002  1
2003 Jiang J, Song Y, Bai C, Koller BH, Matthay MA, Verkman AS. Pleural surface fluorescence measurement of Na+ and Cl- transport across the air space-capillary barrier. Journal of Applied Physiology (Bethesda, Md. : 1985). 94: 343-52. PMID 12391048 DOI: 10.1152/Japplphysiol.00562.2002  1
2002 Mann SE, Ricke EA, Yang BA, Verkman AS, Taylor RN. Expression and localization of aquaporin 1 and 3 in human fetal membranes American Journal of Obstetrics and Gynecology. 187: 902-907. PMID 12388974 DOI: 10.1067/mob.2002.127168  1
2002 Yang B, Bankir L, Gillespie A, Epstein CJ, Verkman AS. Urea-selective concentrating defect in transgenic mice lacking urea transporter UT-B. The Journal of Biological Chemistry. 277: 10633-7. PMID 11792714 DOI: 10.1074/Jbc.M200207200  1
2001 Zhou Q, Clarke L, Nie R, Carnes K, Lai LW, Lien YHH, Verkman A, Lubahn D, Fisher JS, Katzenellenbogen BS, Hess RA. Estrogen action and male fertility: Roles of the sodium/hydrogen exchanger-3 and fluid reabsorption in reproductive tract function Proceedings of the National Academy of Sciences of the United States of America. 98: 14132-14137. PMID 11698654 DOI: 10.1073/Pnas.241245898  1
2001 Thiagarajah JR, Jayaraman S, Naftalin RJ, Verkman AS. In vivo fluorescence measurement of Na(+) concentration in the pericryptal space of mouse descending colon. American Journal of Physiology. Cell Physiology. 281: C1898-903. PMID 11698248 DOI: 10.1152/Ajpcell.2001.281.6.C1898  1
2001 Jayaraman S, Joo NS, Reitz B, Wine JJ, Verkman AS. Submucosal gland secretions in airways from cystic fibrosis patients have normal [Na(+)] and pH but elevated viscosity. Proceedings of the National Academy of Sciences of the United States of America. 98: 8119-23. PMID 11427704 DOI: 10.1073/pnas.131087598  1
2001 Galietta LJ, Springsteel MF, Eda M, Niedzinski EJ, By K, Haddadin MJ, Kurth MJ, Nantz MH, Verkman AS. Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds. The Journal of Biological Chemistry. 276: 19723-8. PMID 11262417 DOI: 10.1074/Jbc.M101892200  1
2001 Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus. The Journal of Biological Chemistry. 276: 2775-9. PMID 11035038 DOI: 10.1074/Jbc.M008216200  1
2001 Verkman AS, Yang B, Skach WR, Mitra A, Song Y, Manley GT, Ma T. Chapter 5 Genetic and biophysical approaches to study water channel biology Current Topics in Membranes. 51: 185-233.  1
2000 Lu Y, Turnbull IR, Bragin A, Carveth K, Verkman AS, Skach WR. Reorientation of aquaporin-1 topology during maturation in the endoplasmic reticulum. Molecular Biology of the Cell. 11: 2973-85. PMID 10982394  1
2000 Foster W, Helm A, Turnbull I, Gulati H, Yang B, Verkman AS, Skach WR. Identification of sequence determinants that direct different intracellular folding pathways for aquaporin-1 and aquaporin-4. The Journal of Biological Chemistry. 275: 34157-65. PMID 10944517 DOI: 10.1074/jbc.M000165200  1
2000 Wiener MC, Verkman AS, Stroud RM, van Hoek AN. Mesoscopic surfactant organization and membrane protein crystallization. Protein Science : a Publication of the Protein Society. 9: 1407-9. PMID 10933509 DOI: 10.1110/Ps.9.7.1407  1
2000 Ma T, Song Y, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Nephrogenic diabetes insipidus in mice lacking aquaporin-3 water channels. Proceedings of the National Academy of Sciences of the United States of America. 97: 4386-91. PMID 10737773 DOI: 10.1073/Pnas.080499597  1
2000 Jayaraman S, Haggie P, Wachter RM, Remington SJ, Verkman AS. Mechanism and cellular applications of a green fluorescent protein-based halide sensor Journal of Biological Chemistry. 275: 6047-6050. PMID 10692389 DOI: 10.1074/Jbc.275.9.6047  1
2000 Lukacs GL, Haggie P, Seksek O, Lechardeur D, Freedman N, Verkman AS. Size-dependent DNA mobility in cytoplasm and nucleus Journal of Biological Chemistry. 275: 1625-1629. PMID 10636854 DOI: 10.1074/Jbc.275.3.1625  1
1999 Ma T, Song Y, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Defective secretion of saliva in transgenic mice lacking aquaporin-5 water channels. The Journal of Biological Chemistry. 274: 20071-4. PMID 10400615 DOI: 10.1074/Jbc.274.29.20071  1
1999 Dayel MJ, Hom EF, Verkman AS. Diffusion of green fluorescent protein in the aqueous-phase lumen of endoplasmic reticulum. Biophysical Journal. 76: 2843-51. PMID 10233100 DOI: 10.1016/S0006-3495(99)77438-2  1
1998 Partikian A, Olveczky B, Swaminathan R, Li Y, Verkman AS. Rapid diffusion of green fluorescent protein in the mitochondrial matrix. The Journal of Cell Biology. 140: 821-9. PMID 9472034 DOI: 10.1083/Jcb.140.4.821  0.36
1998 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Severely impaired urinary concentrating ability in transgenic mice lacking aquaporin-1 water channels. The Journal of Biological Chemistry. 273: 4296-9. PMID 9468475 DOI: 10.1074/Jbc.273.8.4296  1
1997 Canfield MC, Tamarappoo BK, Moses AM, Verkman AS, Holtzman EJ. Identification and characterization of aquaporin-2 water channel mutations causing nephrogenic diabetes insipidus with partial vasopressin response. Human Molecular Genetics. 6: 1865-71. PMID 9302264 DOI: 10.1093/hmg/6.11.1865  1
1997 Ma T, Yang B, Gillespie A, Carlson EJ, Epstein CJ, Verkman AS. Generation and phenotype of a transgenic knockout mouse lacking the mercurial-insensitive water channel aquaporin-4. The Journal of Clinical Investigation. 100: 957-62. PMID 9276712 DOI: 10.1172/Jci231  1
1997 Swaminathan R, Hoang CP, Verkman AS. Photobleaching recovery and anisotropy decay of green fluorescent protein GFP-S65T in solution and cells: Cytoplasmic viscosity probed by green fluorescent protein translational and rotational diffusion Biophysical Journal. 72: 1900-1907. PMID 9083693 DOI: 10.1016/S0006-3495(97)78835-0  1
1997 Agre P, Lee MD, Devidas S, Guggino WB. Aquaporins and ion conductance. Science (New York, N.Y.). 275: 1490; author reply 1. PMID 9045617 DOI: 10.1126/science.275.5305.1490  1
1996 Verkman AS, van Hoek AN, Ma T, Frigeri A, Skach WR, Mitra A, Tamarappoo BK, Farinas J. Water transport across mammalian cell membranes. The American Journal of Physiology. 270: C12-30. PMID 8772426 DOI: 10.1152/Ajpcell.1996.270.1.C12  1
1995 Verkman AS, Shi LB, Frigeri A, Hasegawa H, Farinas J, Mitra A, Skach W, Brown D, Van Hoek AN, Ma T. Structure and function of kidney water channels. Kidney International. 48: 1069-81. PMID 8569068 DOI: 10.1038/Ki.1995.390  1
1995 Mitra AK, van Hoek AN, Wiener MC, Verkman AS, Yeager M. The CHIP28 water channel visualized in ice by electron crystallography. Nature Structural Biology. 2: 726-9. PMID 7552739 DOI: 10.1038/Nsb0995-726  1
1995 Katsura T, Verbavatz J, Farinas J, Ma T, Ausiello DA, Verkman AS, Brown D. Constitutive and regulated membrane expression of aquaporin 1 and aquaporin 2 water channels in stably transfected LLC-PK1 epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 7212-7216. PMID 7543677 DOI: 10.1073/Pnas.92.16.7212  0.36
1995 Frigeri A, Gropper MA, Turck CW, Verkman AS. Immunolocalization of the mercurial-insensitive water channel and glycerol intrinsic protein in epithelial cell plasma membranes Proceedings of the National Academy of Sciences of the United States of America. 92: 4328-4331. PMID 7538665  1
1995 van Hoek AN, Wiener MC, Verbavatz JM, Brown D, Lipniunas PH, Townsend RR, Verkman AS. Purification and structure-function analysis of native, PNGase F-treated, and endo-beta-galactosidase-treated CHIP28 water channels. Biochemistry. 34: 2212-9. PMID 7532004 DOI: 10.1021/Bi00007A015  1
1994 Valenti G, Verbavatz JM, Sabolic I, Ausiello DA, Verkman AS, Brown D. A basolateral CHIP28/MIP26-related protein (BLIP) in kidney principal cells and gastric parietal cells. American Journal of Physiology-Cell Physiology. 267. PMID 7524336 DOI: 10.1152/Ajpcell.1994.267.3.C812  0.36
1994 Skach WR, Shi LB, Calayag MC, Frigeri A, Lingappa VR, Verkman AS. Biogenesis and transmembrane topology of the CHIP28 water channel at the endoplasmic reticulum. The Journal of Cell Biology. 125: 803-15. PMID 7514605 DOI: 10.1083/Jcb.125.4.803  1
1994 Ma T, Hasegawa H, Skach WR, Frigeri A, Verkman AS. Expression, functional analysis, and in situ hybridization of a cloned rat kidney collecting duct water channel. The American Journal of Physiology. 266: C189-97. PMID 7508187  1
1993 Zhang R, Skach W, Hasegawa H, van Hoek AN, Verkman AS. Cloning, functional analysis and cell localization of a kidney proximal tubule water transporter homologous to CHIP28. The Journal of Cell Biology. 120: 359-69. PMID 8421053 DOI: 10.1083/Jcb.120.2.359  1
1993 Verbavatz J-, Brown D, Sabolic I, Valenti G, Ausiello DA, Hoek ANV, Ma T, Verkman AS. Tetrameric assembly of CHIP28 water channels in liposomes and cell membranes: a freeze-fracture study. Journal of Cell Biology. 123: 605-618. PMID 7693713 DOI: 10.1083/Jcb.123.3.605  0.36
1993 Ma T, Frigeri A, Skach W, Verkman AS. Cloning of a novel rat kidney cDNA homologous to CHIP28 and WCH-CD water channels. Biochemical and Biophysical Research Communications. 197: 654-9. PMID 7505572 DOI: 10.1006/Bbrc.1993.2529  1
1992 Periasamy N, Kao HP, Fushimi K, Verkman AS. Organic osmolytes increase cytoplasmic viscosity in kidney cells. The American Journal of Physiology. 263: C901-7. PMID 1415675 DOI: 10.1152/AJPCELL.1992.263.4.C901  0.4
1992 Sabolic I, Wuarin F, Shi LB, Verkman AS, Ausiello DA, Gluck S, Brown D. Apical Endosomes Isolated from Kidney Collecting Duct Principal Cells Lack Subunits of the Proton Pumping ATPase Journal of Cell Biology. 119: 111-122. PMID 1388176 DOI: 10.1083/Jcb.119.1.111  0.36
1992 Biwersi J, Farah N, Wang YX, Ketcham R, Verkman AS. Synthesis of cell-impermeable Cl-sensitive fluorescent indicators with improved sensitivity and optical properties. The American Journal of Physiology. 262: C242-50. PMID 1370743 DOI: 10.1152/ajpcell.1992.262.1.C243  1
1992 Sabolić I, Shi L, Brown D, Ausiello DA, Verkman AS. Proteinases inhibit H(+)-ATPase and Na+/H+ exchange but not water transport in apical and endosomal membranes from rat proximal tubule. Biochimica Et Biophysica Acta. 1103: 137-147. PMID 1309658 DOI: 10.1016/0005-2736(92)90067-V  0.36
1992 Sabolic I, Valenti G, Verbavatz JM, Hoek ANV, Verkman AS, Ausiello DA, Brown D. Localization of the CHIP28 water channel in rat kidney. American Journal of Physiology-Cell Physiology. 263. PMID 1282299 DOI: 10.1152/Ajpcell.1992.263.6.C1225  0.36
1992 Hasegawa H, Skach W, Baker O, Calayag MC, Lingappa V, Verkman AS. A multifunctional aqueous channel formed by CFTR. Science (New York, N.Y.). 258: 1477-9. PMID 1279809 DOI: 10.1126/Science.1279809  1
1991 Verkman AS, Armijo M, Fushimi K. Construction and evaluation of a frequency-domain epifluorescence microscope for lifetime and anisotropy decay measurements in subcellular domains Biophysical Chemistry. 40: 117-125. PMID 1873470 DOI: 10.1016/0301-4622(91)85036-P  1
1990 Roe JN, Szoka FC, Verkman AS. Fibre optic sensor for the detection of potassium using fluorescence energy transfer The Analyst. 115: 353-358. PMID 2363517 DOI: 10.1039/An9901500353  1
1990 Dix JA. Pyrene Eximer Mapping in Cultured Fibroblasts by Ratio Imaging and Time-Resolved Microscopy Biochemistry. 1949-1953. PMID 2331474 DOI: 10.1021/BI00459A041  1
1990 Fushimi K, Dix JA, Verkman AS. Cell membrane fluidity in the intact kidney proximal tubule measured by orientation-independent fluorescence anisotropy imaging Biophysical Journal. 57: 241-254. PMID 2317549 DOI: 10.1016/S0006-3495(90)82527-3  1
1990 Dix JA, Verkman AS. Mapping of fluorescence anisotropy in living cells by ratio imaging. Application to cytoplasmic viscosity Biophysical Journal. 57: 231-240. PMID 2317548 DOI: 10.1016/S0006-3495(90)82526-1  1
1990 Lencer WI, Brown D, Ausiello DA, Verkman AS. Endocytosis of water channels in rat kidney: cell specificity and correlation with in vivo antidiuresis. American Journal of Physiology-Cell Physiology. 259. PMID 1701969 DOI: 10.1152/Ajpcell.1990.259.6.C920  0.36
1990 Lencer WI, Verkman AS, Arnaout MA, Ausiello DA, Brown D. Endocytic vesicles from renal papilla which retrieve the vasopressin-sensitive water channel do not contain a functional H+ ATPase. Journal of Cell Biology. 111: 379-389. PMID 1696262 DOI: 10.1083/Jcb.111.2.379  0.36
1990 Lencer WI, Weyer P, Verkman AS, Ausiello DA, Brown D. FITC-dextran as a probe for endosome function and localization in kidney. American Journal of Physiology-Cell Physiology. 258. PMID 1689545 DOI: 10.1152/Ajpcell.1990.258.2.C309  0.36
1989 Roe JN, Szoka FC, Verkman AS. Optical measurement of aqueous potassium concentration by a hydrophobic indicator in lipid vesicles Biophysical Chemistry. 33: 295-302. PMID 2804247 DOI: 10.1016/0301-4622(89)80031-6  1
1989 Holmberg EG, Verkman AS, Dix JA. Mechanism of acridine orange interaction with phospholipids and proteins in renal microvillus vesicles Biophysical Chemistry. 33: 245-256. PMID 2804243 DOI: 10.1016/0301-4622(89)80026-2  1
1989 Calafut TM, Dix JA, Verkman AS. Fluorescence depolarization of cis- and trans-parinaric acids in artificial and red cell membranes resolved by a double hindered rotational model. Biochemistry. 28: 5051-8. PMID 2765524 DOI: 10.1021/BI00438A023  1
1989 Verkman AS, Takla R, Sefton B, Basbaum C, Widdicombe JH. Quantitative fluorescence measurement of chloride transport mechanisms in phospholipid vesicles. Biochemistry. 28: 4240-4. PMID 2765484 DOI: 10.1021/Bi00436A018  1
1989 Verkman AS, Sellers MC, Chao AC, Leung T, Ketcham R. Synthesis and characterization of improved chloride-sensitive fluorescent indicators for biological applications. Analytical Biochemistry. 178: 355-61. PMID 2751097 DOI: 10.1016/0003-2697(89)90652-0  1
1989 Ye R, Verkman AS. Simultaneous optical measurement of osmotic and diffusional water permeability in cells and liposomes Biochemistry. 28: 824-829. PMID 2540807 DOI: 10.1021/BI00428A062  1
1989 Chao AC, Dix JA, Sellers MC, Verkman AS. Fluorescence measurement of chloride transport in monolayer cultured cells. Mechanisms of chloride transport in fibroblasts Biophysical Journal. 56: 1071-1081. PMID 2482083 DOI: 10.1016/S0006-3495(89)82755-9  1
1989 Roe JN, Szoka FC, Verkman AS. Colorimetric detection of alkali metals by ion-pair extraction Applied Spectroscopy. 43: 656-661. DOI: 10.1366/0003702894202607  1
1986 Verkman AS, Fraser CL. Water and nonelectrolyte permeability in brain synaptosomes isolated from normal and uremic rats American Journal of Physiology - Regulatory Integrative and Comparative Physiology. 250. PMID 3946644 DOI: 10.1152/AJPREGU.1986.250.2.R306  1
1986 Dix JA, Verkman AS, Solomon AK. Binding of chloride and a disulfonic stilbene transport inhibitor to red cell band 3. The Journal of Membrane Biology. 89: 211-23. PMID 3701841 DOI: 10.1007/BF01870665  1
1986 Verkman AS, Lukacovic MF, Tinklepaugh MS, Dix JA. Quenching of red cell tryptophan fluorescence by mercurial compounds Molecular Membrane Biology. 6: 269-289. PMID 3574139 DOI: 10.3109/09687688609065453  1
1985 Forman SA, Verkman AS, Dix JA, Solomon AK. n-Alkanols and halothane inhibit red cell anion transport and increase band 3 conformational change rate. Biochemistry. 24: 4859-66. PMID 4074663  1
1985 Verkman AS, Dix JA, Seifter JL. Water and urea transport in renal microvillus membrane vesicles. The American Journal of Physiology. 248: F650-5. PMID 3993788 DOI: 10.1152/AJPRENAL.1985.248.5.F650  1
1985 Verkman AS, Dix JA, Seifter JL, Skorecki KL, Jung CY, Ausiello DA. Radiation inactivation studies of renal brush border water and urea transport. The American Journal of Physiology. 249: F806-12. PMID 3934983 DOI: 10.1152/AJPRENAL.1985.249.6.F806  1
1985 Dix JA, Ausiello DA, Jung CY, Verkman AS. Target analysis studies of red cell water and urea transport Bba - Biomembranes. 821: 243-252. PMID 2998469 DOI: 10.1016/0005-2736(85)90093-8  1
1984 Verkman AS, Dix JA. Effect of unstirred layers on binding and reaction kinetics at a membrane surface Analytical Biochemistry. 142: 109-116. PMID 6517306 DOI: 10.1016/0003-2697(84)90524-4  1
1984 Lukacovic MF, Verkman AS, Dix JA, Solomon AK. Specific interaction of the water transport inhibitor, pCMBS, with band 3 in red blood cell membranes. Biochimica Et Biophysica Acta. 778: 253-9. PMID 6093883 DOI: 10.1016/0005-2736(84)90366-3  1
1983 Verkman AS, Dix JA, Solomon AK. Anion transport inhibitor binding to band 3 in red blood cell membranes. The Journal of General Physiology. 81: 421-49. PMID 6842178  1
1983 Solomon AK, Chasan B, Dix JA, Lukacovic MF, Toon MR, Verkman AS. The aqueous pore in the red cell membrane: band 3 as a channel for anions, cations, nonelectrolytes, and water. Annals of the New York Academy of Sciences. 414: 97-124. PMID 6322657  0.44
1982 Verkman AS, Solomon AK. A stepwise mechanism for the permeation of phloretin through a lipid bilayer. The Journal of General Physiology. 80: 557-81. PMID 7142954  1
1982 Forman SA, Verkman AS, Dix JA, Solomon AK. Interaction of phloretin with the anion transport protein of the red blood cell membrane. Biochimica Et Biophysica Acta. 689: 531-8. PMID 7126563 DOI: 10.1016/0005-2736(82)90311-X  1
1981 Verkman AS, Dix JA, Pandiscio AA. A simple stopped-flow temperature-jump apparatus Analytical Biochemistry. 117: 164-169. PMID 7316188 DOI: 10.1016/0003-2697(81)90706-5  1
1980 Verkman AS, Solomon AK. Kinetics of phloretin binding to phosphatidylcholine vesicle membranes. The Journal of General Physiology. 75: 673-92. PMID 7391812  1
1980 Verkman AS, Pandiscio AA, Jennings M, Solomon AK. An improved temperature-jump apparatus. Analytical Biochemistry. 102: 189-95. PMID 7356153 DOI: 10.1016/0003-2697(80)90337-1  1
1979 Dix JA, Verkman AS, Solomon AK, Cantley LC. Human erythrocyte anion exchange site characterised using a fluorescent probe. Nature. 282: 520-2. PMID 503233 DOI: 10.1038/282520A0  1
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