Paul Talalay, M.D. - Publications

Affiliations: 
Molecular Pharmacology Johns Hopkins University, Baltimore, MD 
Area:
chemical protection against carcinogenesis
Website:
http://www.jhu.edu/jhumag/0408web/talalay.html

194 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2015 Fahey JW, Holtzclaw WD, Wehage SL, Wade KL, Stephenson KK, Talalay P. Sulforaphane Bioavailability from Glucoraphanin-Rich Broccoli: Control by Active Endogenous Myrosinase. Plos One. 10: e0140963. PMID 26524341 DOI: 10.1371/journal.pone.0140963  0.48
2015 Brown RH, Reynolds C, Brooker A, Talalay P, Fahey JW. Sulforaphane improves the bronchoprotective response in asthmatics through Nrf2-mediated gene pathways. Respiratory Research. 16: 106. PMID 26369337 DOI: 10.1186/s12931-015-0253-z  0.48
2015 Knatko EV, Ibbotson SH, Zhang Y, Higgins M, Fahey JW, Talalay P, Dawe RS, Ferguson J, Huang JT, Clarke R, Zheng S, Saito A, Kalra S, Benedict AL, Honda T, et al. Nrf2 Activation Protects against Solar-Simulated Ultraviolet Radiation in Mice and Humans. Cancer Prevention Research (Philadelphia, Pa.). 8: 475-86. PMID 25804610 DOI: 10.1158/1940-6207.CAPR-14-0362  0.48
2015 Talalay P, Zimmerman AW. Reply to Scahill: Behavioral outcome measures in autism Proceedings of the National Academy of Sciences of the United States of America. 112: E350. DOI: 10.1073/pnas.1422473112  0.48
2015 Wang J, Cao P, Liu C, Talalay PG. Comparison and analysis of subglacial bedrock core drilling technology in Polar Regions Polar Science. 9: 208-220. DOI: 10.1016/j.polar.2015.03.003  0.32
2015 Cao P, Yang C, Chen Y, Chen B, Talalay P. Experimental study of the drilling process in debris-rich ice Cold Regions Science and Technology. 120: 138-144. DOI: 10.1016/j.coldregions.2015.10.001  0.32
2015 Talalay P, Yang C, Cao P, Wang R, Zhang N, Fan X, Yang Y, Sun Y. Ice-core drilling problems and solutions Cold Regions Science and Technology. 120: 1-20. DOI: 10.1016/j.coldregions.2015.08.014  0.32
2015 Hong J, Fan X, Liu Y, Liu G, Liu B, Talalay P. Size distribution and shape characteristics of ice cuttings produced by an electromechanical auger drill Cold Regions Science and Technology. 119: 204-210. DOI: 10.1016/j.coldregions.2015.08.012  0.32
2015 Cao P, Chen B, Liu C, Yang C, Talalay P. Experimental investigation of cutting temperature in ice drilling Cold Regions Science and Technology. 116: 78-85. DOI: 10.1016/j.coldregions.2015.04.008  0.32
2014 Singh K, Connors SL, Macklin EA, Smith KD, Fahey JW, Talalay P, Zimmerman AW. Sulforaphane treatment of autism spectrum disorder (ASD). Proceedings of the National Academy of Sciences of the United States of America. 111: 15550-5. PMID 25313065 DOI: 10.1073/pnas.1416940111  0.48
2014 Egner PA, Chen JG, Zarth AT, Ng DK, Wang JB, Kensler KH, Jacobson LP, Muñoz A, Johnson JL, Groopman JD, Fahey JW, Talalay P, Zhu J, Chen TY, Qian GS, et al. Rapid and sustainable detoxication of airborne pollutants by broccoli sprout beverage: results of a randomized clinical trial in China. Cancer Prevention Research (Philadelphia, Pa.). 7: 813-23. PMID 24913818 DOI: 10.1158/1940-6207.CAPR-14-0103  0.48
2014 Talalay P, Fan X, Zheng Z, Xue J, Cao P, Zhang N, Wang R, Yu D, Yu C, Zhang Y, Zhang Q, Su K, Yang D, Zhan J. Anti-torque systems of electromechanical cable-suspended drills and test results Annals of Glaciology. 55: 207-218. DOI: 10.3189/2014AoG68A025  0.32
2014 Talalay PG. Perspectives for development of ice-core drilling technology: A discussion Annals of Glaciology. 55: 339-350. DOI: 10.3189/2014AoG68A007  0.32
2014 Zhang N, An C, Fan X, Shi G, Li C, Liu J, Hu Z, Talalay P, Sun Y, Li Y. Chinese First Deep Ice-Core Drilling Project DK-1 at Dome A, Antarctica (2011-2013): Progress and performance Annals of Glaciology. 55: 88-98. DOI: 10.3189/2014AoG68A006  0.32
2014 Xu H, Han L, Cao P, Guo M, Han J, Yu D, Talalay P. Low-molecular-weight, fatty-acid esters as potential low-temperature drilling fluids for ice coring Annals of Glaciology. 55: 39-43. DOI: 10.3189/2014AoG68A003  0.32
2014 Hong J, Talalay P, Sysoev M, Fan X. DEM modeling of ice cuttings transportation by electromechanical auger core drills Annals of Glaciology. 55: 65-71. DOI: 10.3189/2014AoG68A002  0.32
2014 Cao P, Yang C, Zheng Z, Wang R, Zhang N, Liu C, Hu Z, Talalay P. Low-load diamond drill bits for subglacial bedrock sampling Annals of Glaciology. 55: 124-130. DOI: 10.3189/2014AoG68A001  0.32
2014 Talalay P, Hu Z, Xu H, Yu D, Han L, Han J, Wang L. Environmental considerations of lowerature drilling fluids Annals of Glaciology. 55: 31-40. DOI: 10.3189/2014AoG65A226  0.32
2014 Talalay PG, Zagorodnov VS, Markov AN, Sysoev MA, Hong J. Recoverable autonomous sonde (RECAS) for environmental exploration of Antarctic subglacial lakes: General concept Annals of Glaciology. 55: 23-30. DOI: 10.3189/2014AoG65A003  0.32
2014 Talalay P, Fan X, Xu H, Yu D, Han L, Han J, Sun Y. Drilling fluid technology in ice sheets: Hydrostatic pressure and borehole closure considerations Cold Regions Science and Technology. 98: 47-54. DOI: 10.1016/j.coldregions.2013.10.012  0.32
2014 Talalay PG. Drill heads of the deep ice electromechanical drills Cold Regions Science and Technology. 97: 41-56. DOI: 10.1016/j.coldregions.2013.09.009  0.32
2013 Liu H, Talalay P. Relevance of anti-inflammatory and antioxidant activities of exemestane and synergism with sulforaphane for disease prevention Proceedings of the National Academy of Sciences of the United States of America. 110: 19065-19070. PMID 24191056 DOI: 10.1073/pnas.1318247110  0.48
2013 Ushida Y, Talalay P. Sulforaphane accelerates acetaldehyde metabolism by inducing aldehyde dehydrogenases: Relevance to ethanol intolerance Alcohol and Alcoholism. 48: 526-534. PMID 23825090 DOI: 10.1093/alcalc/agt063  0.48
2013 Fahey JW, Stephenson KK, Wade KL, Talalay P. Urease from Helicobacter pylori is inactivated by sulforaphane and other isothiocyanates. Biochemical and Biophysical Research Communications. 435: 1-7. PMID 23583386 DOI: 10.1016/j.bbrc.2013.03.126  0.48
2013 Kensler TW, Egner PA, Agyeman AS, Visvanathan K, Groopman JD, Chen JG, Chen TY, Fahey JW, Talalay P. Keap1-nrf2 signaling: a target for cancer prevention by sulforaphane. Topics in Current Chemistry. 329: 163-77. PMID 22752583 DOI: 10.1007/128_2012_339  0.48
2013 Talalay PG. Subglacial till and bedrock drilling Cold Regions Science and Technology. 86: 142-166. DOI: 10.1016/j.coldregions.2012.08.009  0.32
2012 Benedict AL, Mountney A, Hurtado A, Bryan KE, Schnaar RL, Dinkova-Kostova AT, Talalay P. Neuroprotective effects of sulforaphane after contusive spinal cord injury Journal of Neurotrauma. 29: 2576-2586. PMID 22853439 DOI: 10.1089/neu.2012.2474  0.48
2012 Fahey JW, Wehage SL, Holtzclaw WD, Kensler TW, Egner PA, Shapiro TA, Talalay P. Protection of humans by plant glucosinolates: Efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora Cancer Prevention Research. 5: 603-611. PMID 22318753 DOI: 10.1158/1940-6207.CAPR-11-0538  0.48
2012 Fahey JW, Talalay P, Kensler TW. Notes from the field: "Green" chemoprevention as frugal medicine Cancer Prevention Research. 5: 179-188. PMID 22307565 DOI: 10.1158/1940-6207.CAPR-11-0572  0.48
2012 Kensler TW, Ng D, Carmella SG, Chen M, Jacobson LP, Muñoz A, Egner PA, Chen JG, Qian GS, Chen TY, Fahey JW, Talalay P, Groopman JD, Yuan JM, Hecht SS. Modulation of the metabolism of airborne pollutants by glucoraphanin-rich and sulforaphane-rich broccoli sprout beverages in Qidong, China. Carcinogenesis. 33: 101-7. PMID 22045030 DOI: 10.1093/carcin/bgr229  0.48
2011 Healy ZR, Liu H, Holtzclaw WD, Talalay P. Inactivation of tautomerase activity of macrophage migration inhibitory factor by sulforaphane: A potential biomarker for anti-inflammatory intervention Cancer Epidemiology Biomarkers and Prevention. 20: 1516-1523. PMID 21602309 DOI: 10.1158/1055-9965.EPI-11-0279  0.48
2011 Egner PA, Chen JG, Wang JB, Wu Y, Sun Y, Lu JH, Zhu J, Zhang YH, Chen YS, Friesen MD, Jacobson LP, Muñoz A, Ng D, Qian GS, Zhu YR, ... ... Talalay P, et al. Bioavailability of Sulforaphane from two broccoli sprout beverages: results of a short-term, cross-over clinical trial in Qidong, China. Cancer Prevention Research (Philadelphia, Pa.). 4: 384-95. PMID 21372038 DOI: 10.1158/1940-6207.CAPR-10-0296  0.48
2011 Suganuma H, Fahey JW, Bryan KE, Healy ZR, Talalay P. Stimulation of phagocytosis by sulforaphane Biochemical and Biophysical Research Communications. 405: 146-151. PMID 21219867 DOI: 10.1016/j.bbrc.2011.01.025  0.48
2011 Vasiliev NI, Talalay PG. Twenty years of drilling the deepest hole in ice Scientific Drilling. 41-45. DOI: 10.2204/iodp.sd.11.05.2011  0.32
2010 Dinkova-Kostova AT, Talalay P, Sharkey J, Zhang Y, Holtzclaw WD, Wang XJ, David E, Schiavoni KH, Finlayson S, Mierke DF, Honda T. An exceptionally potent inducer of cytoprotective enzymes: elucidation of the structural features that determine inducer potency and reactivity with Keap1. The Journal of Biological Chemistry. 285: 33747-55. PMID 20801881 DOI: 10.1074/jbc.M110.163485  0.48
2010 Ahn YH, Hwang Y, Liu H, Wang XJ, Zhang Y, Stephenson KK, Boronina TN, Cole RN, Dinkova-Kostova AT, Talalay P, Cole PA. Electrophilic tuning of the chemoprotective natural product sulforaphane Proceedings of the National Academy of Sciences of the United States of America. 107: 9590-9595. PMID 20439747 DOI: 10.1073/pnas.1004104107  0.48
2010 Bensasson RV, Zoete V, Berthier G, Talalay P, Dinkova-Kostova AT. Potency ranking of triterpenoids as inducers of a cytoprotective enzyme and as inhibitors of a cellular inflammatory response via their electron affinity and their electrophilicity index. Chemico-Biological Interactions. 186: 118-26. PMID 20433811 DOI: 10.1016/j.cbi.2010.04.026  0.48
2010 Dinkova-Kostova AT, Talalay P. NAD(P)H:quinone acceptor oxidoreductase 1 (NQO1), a multifunctional antioxidant enzyme and exceptionally versatile cytoprotector Archives of Biochemistry and Biophysics. 501: 116-123. PMID 20361926 DOI: 10.1016/j.abb.2010.03.019  0.48
2010 Dinkova-Kostova AT, Fahey JW, Benedict AL, Jenkins SN, Ye L, Wehage SL, Talalay P. Dietary glucoraphanin-rich broccoli sprout extracts protect against UV radiation-induced skin carcinogenesis in SKH-1 hairless mice Photochemical and Photobiological Sciences. 9: 597-600. PMID 20354656 DOI: 10.1039/b9pp00130a  0.48
2009 Healy ZR, Dinkova-Kostova AT, Wehage SL, Thompson RE, Fahey JW, Talalay P. Precise determination of the erythema response of human skin to ultraviolet radiation and quantification of effects of protectors. Photodermatology, Photoimmunology & Photomedicine. 25: 45-50. PMID 19152516 DOI: 10.1111/j.1600-0781.2009.00404.x  0.48
2008 Dinkova-Kostova AT, Fahey JW, Jenkins SN, Wehage SL, Talalay P. Rapid body weight gain increases the risk of UV radiation-induced skin carcinogenesis in SKH-1 hairless mice Nutrition Research. 28: 539-543. PMID 19083457 DOI: 10.1016/j.nutres.2008.05.009  0.48
2008 Liu H, Dinkova-Kostova AT, Talalay P. Coordinate regulation of enzyme markers for inflammation and for protection against oxidants and electrophiles Proceedings of the National Academy of Sciences of the United States of America. 105: 15926-15931. PMID 18838692 DOI: 10.1073/pnas.0808346105  0.48
2008 Bensasson RV, Zoete V, Dinkova-Kostova AT, Talalay P. Two-step mechanism of induction of the gene expression of a prototypic cancer-protective enzyme by diphenols Chemical Research in Toxicology. 21: 805-812. PMID 18361512 DOI: 10.1021/tx7002883  0.48
2008 Dinkova-Kostova AT, Talalay P. Direct and indirect antioxidant properties of inducers of cytoprotective proteins Molecular Nutrition and Food Research. 52: S128-S138. PMID 18327872 DOI: 10.1002/mnfr.200700195  0.48
2008 Dinkova-Kostova AT, Jenkins SN, Wehage SL, Huso DL, Benedict AL, Stephenson KK, Fahey JW, Liu H, Liby KT, Honda T, Gribble GW, Sporn MB, Talalay P. A dicyanotriterpenoid induces cytoprotective enzymes and reduces multiplicity of skin tumors in UV-irradiated mice Biochemical and Biophysical Research Communications. 367: 859-865. PMID 18206646 DOI: 10.1016/j.bbrc.2008.01.026  0.48
2007 Talalay P, Fahey JW, Healy ZR, Wehage SL, Benedict AL, Min C, Dinkova-Kostova AT. Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation Proceedings of the National Academy of Sciences of the United States of America. 104: 17500-17505. PMID 17956979 DOI: 10.1073/pnas.0708710104  0.48
2007 Kerns ML, DePianto D, Dinkova-Kostova AT, Talalay P, Coulombe PA. Reprogramming of keratin biosynthesis by sulforaphane restores skin integrity in epidermolysis bullosa simplex Proceedings of the National Academy of Sciences of the United States of America. 104: 14460-14465. PMID 17724334 DOI: 10.1073/pnas.0706486104  0.48
2007 Liby K, Honda T, Williams CR, Risingsong R, Royce DB, Suh N, Dinkova-Kostova AT, Stephenson KK, Talalay P, Sundararajan C, Gribble GW, Sporn MB. Novel semisynthetic analogues of betulinic acid with diverse cytoprotective, antiproliferative, and proapoptotic activities Molecular Cancer Therapeutics. 6: 2113-2119. PMID 17620440 DOI: 10.1158/1535-7163.MCT-07-0180  0.48
2007 Dinkova-Kostova AT, Cheah J, Samouilov A, Zweier JL, Bozak RE, Hicks RJ, Talalay P. Phenolic Michael reaction acceptors: Combined direct and indirect antioxidant defenses against electrophiles and oxidants Medicinal Chemistry. 3: 261-268. PMID 17504197 DOI: 10.2174/157340607780620680  0.48
2007 Dinkova-Kostova AT, Fahey JW, Wade KL, Jenkins SN, Shapiro TA, Fuchs EJ, Kerns ML, Talalay P. Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 16: 847-51. PMID 17416783 DOI: 10.1158/1055-9965.EPI-06-0934  0.48
2007 Cornblatt BS, Ye L, Dinkova-Kostova AT, Erb M, Fahey JW, Singh NK, Chen MSA, Stierer T, Garrett-Mayer E, Argani P, Davidson NE, Talalay P, Kensler TW, Visvanathan K. Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast Carcinogenesis. 28: 1485-1490. PMID 17347138 DOI: 10.1093/carcin/bgm049  0.48
2007 Augustin LJ, Motoyama H, Wilhelms F, Johnsen SJ, Hansen SB, Talalay P, Vasiliev NI. Drilling comparison in 'warm ice' and drill design comparison Annals of Glaciology. 47: 73-78. DOI: 10.3189/172756407786857820  0.32
2007 Talalay PG, Hooke RL. Closure of deep boreholes in ice sheets: A discussion Annals of Glaciology. 47: 125-133. DOI: 10.3189/172756407786857794  0.32
2007 Talalay PG. Dimethyl siloxane oils as an alternative borehole fluid Annals of Glaciology. 47: 82-88. DOI: 10.3189/172756407786857785  0.32
2007 Vasiliev NI, Talalay PG, Bobin NE, Chistyakov VK, Zubkov VM, Krasilev AV, Dmitriev AN, Yankilevich SV, Lipenkov VY. Deep drilling at Vostok station, Antarctica: History and recent events Annals of Glaciology. 47: 10-23. DOI: 10.3189/172756407786857776  0.32
2007 Johnsen SJ, Hansen SB, Sheldon SG, Dahl-Jensen D, Steffensen JP, Augustin LJ, Journé P, Alemany O, Rufli H, Schwander J, Azuma N, Motoyama H, Popp T, Talalay PG, Thorsteinsson T, et al. The Hans Tausen drill: Design, performance, further developments and some lessons learned Annals of Glaciology. 47: 89-98. DOI: 10.3189/172756407786857686  0.32
2006 Shapiro TA, Fahey JW, Dinkova-Kostova AT, Holtzclaw WD, Stephenson KK, Wade KL, Ye L, Talalay P. Safety, tolerance, and metabolism of broccoli sprout glucosinolates and isothiocyanates: A clinical phase I study Nutrition and Cancer. 55: 53-62. PMID 16965241 DOI: 10.1207/s15327914nc5501_7  0.48
2006 Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P. Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts Cancer Letters. 240: 243-252. PMID 16271437 DOI: 10.1016/j.canlet.2005.09.012  0.48
2006 Talalay PG. Removal of cuttings in deep ice electromechanical drills Cold Regions Science and Technology. 44: 87-98. DOI: 10.1016/j.coldregions.2004.08.005  0.32
2005 Kensler TW, Chen JG, Egner PA, Fahey JW, Jacobson LP, Stephenson KK, Ye L, Coady JL, Wang JB, Wu Y, Sun Y, Zhang QN, Zhang BC, Zhu YR, Qian GS, ... ... Talalay P, et al. Effects of glucosinolate-rich broccoli sprouts on urinary levels of aflatoxin-DNA adducts and phenanthrene tetraols in a randomized clinical trial in He Zuo township, Qidong, People's Republic of China. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 14: 2605-13. PMID 16284385 DOI: 10.1158/1055-9965.EPI-05-0368  0.48
2005 Healy ZR, Lee NH, Gao X, Goldring MB, Talalay P, Kensler TW, Konstantopoulos K. Divergent responses of chondrocytes and endothelial cells to shear stress: Cross-talk among COX-2, the phase 2 response, and apoptosis Proceedings of the National Academy of Sciences of the United States of America. 102: 14010-14015. PMID 16172382 DOI: 10.1073/pnas.0506620102  0.48
2005 Talalay P. A fascination with enzymes: The journey not the arrival matters Journal of Biological Chemistry. 280: 28829-28847. PMID 15941714 DOI: 10.1074/jbc.X500004200  0.48
2005 Fahey JW, Stephenson KK, Dinkova-Kostova AT, Egner PA, Kensler TW, Talalay P. Chlorophyll, chlorophyllin and related tetrapyrroles are significant inducers of mammalian phase 2 cytoprotective genes Carcinogenesis. 26: 1247-1255. PMID 15774490 DOI: 10.1093/carcin/bgi068  0.48
2005 Dinkova-Kostova AT, Liby KT, Stephenson KK, Holtzclaw WD, Gao X, Suh N, Williams C, Risingsong R, Honda T, Gribble GW, Sporn MB, Talalay P. Extremely potent triterpenoid inducers of the phase 2 response: Correlations of protection against oxidant and inflammatory stress Proceedings of the National Academy of Sciences of the United States of America. 102: 4584-4589. PMID 15767573 DOI: 10.1073/pnas.0500815102  0.48
2005 Healy ZR, Lee N, Talalay P, Kensler T, Konstantopoulos K. Elucidation of intracellular signaling pathways in shear-activated chondrocytes: A role in arthritis Aiche Annual Meeting, Conference Proceedings. 8072.  0.48
2004 Holtzclaw WD, Dinkova-Kostova AT, Talalay P. Protection against electrophile and oxidative stress by induction of phase 2 genes: The quest for the elusive sensor that responds to inducers Advances in Enzyme Regulation. 44: 335-367. PMID 15581500 DOI: 10.1016/j.advenzreg.2003.11.013  0.48
2004 Fahey JW, Muñoz A, Matsuzaki Y, Suzuki H, Talalay P, Tauchi M, Zhang S, Hurt C, Yanaka A. Dietary amelioration of Helicobacter pylori infection: Design criteria for a clinical trial Cancer Epidemiology Biomarkers and Prevention. 13: 1610-1616. PMID 15466977  0.48
2004 Gao X, Talalay P. Induction of phase 2 genes by sulforaphane protects, retinal pigment epithelial cells against photooxidative damage Proceedings of the National Academy of Sciences of the United States of America. 101: 10446-10451. PMID 15229324 DOI: 10.1073/pnas.0403886101  0.48
2004 Zoete V, Rougée M, Dinkova-Kostova AT, Talalay P, Bensasson RV. Redox ranking of inducers of a cancer-protective enzyme via the energy of their highest occupied molecular orbital Free Radical Biology and Medicine. 36: 1418-1423. PMID 15135178 DOI: 10.1016/j.freeradbiomed.2004.03.008  0.48
2004 Dinkova-Kostova AT, Fahey JW, Talalay P. Chemical Structures of Inducers of Nicotinamide Quinone Oxidoreductase 1 (NQO1) Methods in Enzymology. 382: 423-448. PMID 15047115 DOI: 10.1016/S0076-6879(04)82023-8  0.48
2004 Talalay P, Dinkova-Kostova AT. Role of Nicotinamide Quinone Oxidoreductase 1 (NQO1) in Protection against Toxicity of Electrophiles and Reactive Oxygen Intermediates Methods in Enzymology. 382: 355-364. PMID 15047111 DOI: 10.1016/S0076-6879(04)82019-6  0.48
2004 Fahey JW, Dinkova-Kostova AT, Stephenson KK, Talalay P. The "Prochaska" Microtiter Plate Bioassay for Inducers of NQO1 Methods in Enzymology. 382: 243-258. PMID 15047106 DOI: 10.1016/S0076-6879(04)82014-7  0.48
2004 Wakabayashi N, Dinkova-Kostova AT, Holtzclaw WD, Kang MI, Kobayashi A, Yamamoto M, Kensler TW, Talalay P. Protection against electrophile and oxidant stress by induction of the phase 2 response: Fate of cysteines of the Keap1 sensor modified by inducers Proceedings of the National Academy of Sciences of the United States of America. 101: 2040-2045. PMID 14764894 DOI: 10.1073/pnas.0307301101  0.48
2003 Talalay P, Dinkova-Kostova AT, Holtzclaw WD. Importance of phase 2 gene regulation in protection against electrophile and reactive oxygen toxicity and carcinogenesis Advances in Enzyme Regulation. 43: 121-134. PMID 12791387 DOI: 10.1016/S0065-2571(02)00038-9  0.48
2003 Mambo E, Gao X, Cohen Y, Guo Z, Talalay P, Sidransky D. Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations Proceedings of the National Academy of Sciences of the United States of America. 100: 1838-1843. PMID 12578990 DOI: 10.1073/pnas.0437910100  0.48
2003 Talalay PG. Power consumption of deep ice electromechanical drills Cold Regions Science and Technology. 37: 69-79. DOI: 10.1016/S0165-232X(03)00036-3  0.32
2002 Talalay P. Harnessing the anticancer power of plants. The Johns Hopkins Medical Letter Health After 50. 14: 6. PMID 2002138834  0.48
2002 Dinkova-Kostova AT, Holtzclaw WD, Cole RN, Itoh K, Wakabayashi N, Katoh Y, Yamamoto M, Talalay P. Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants Proceedings of the National Academy of Sciences of the United States of America. 99: 11908-11913. PMID 12193649 DOI: 10.1073/pnas.172398899  0.48
2002 Fahey JW, Haristoy X, Dolan PM, Kensler TW, Scholtus I, Stephenson KK, Talalay P, Lozniewski A. Sulforaphane inhibits extracellular, intracellular, and antibiotic-resistant strains of Helicobacter pylori and prevents benzo[a]pyrene-induced stomach tumors Proceedings of the National Academy of Sciences of the United States of America. 99: 7610-7615. PMID 12032331 DOI: 10.1073/pnas.112203099  0.48
2002 Ye L, Dinkova-Kostova AT, Wade KL, Zhang Y, Shapiro TA, Talalay P. Quantitative determination of dithiocarbamates in human plasma, serum, erythrocytes and urine: Pharmacokinetics of broccoli sprout isothiocyanates in humans Clinica Chimica Acta. 316: 43-53. PMID 11750273 DOI: 10.1016/S0009-8981(01)00727-6  0.48
2001 Gao X, Dinkova-Kostova AT, Talalay P. Powerful and prolonged protection of human retinal pigment epithelial cells, keratinocytes, and mouse leukemia cells against oxidative damage: The indirect antioxidant effects of sulforaphane Proceedings of the National Academy of Sciences of the United States of America. 98: 15221-15226. PMID 11752465 DOI: 10.1073/pnas.261572998  0.48
2001 Talalay P, Fahey JW. Phytochemicals from cruciferous plants protect against cancer by modulating carcinogen metabolism Journal of Nutrition. 131: 3027S-3033S. PMID 11694642  0.48
2001 Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P. Chemoprotective glucosinolates and isothiocyanates of broccoli sprouts: Metabolism and excretion in humans Cancer Epidemiology Biomarkers and Prevention. 10: 501-508. PMID 11352861  0.48
2001 Ramos-Gomez M, Kwak MK, Dolan PM, Itoh K, Yamamoto M, Talalay P, Kensler TW. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 98: 3410-3415. PMID 11248092 DOI: 10.1073/pnas.051618798  0.48
2001 Dinkova-Kostova AT, Massiah MA, Bozak RE, Hicks RJ, Talalay P. Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups Proceedings of the National Academy of Sciences of the United States of America. 98: 3404-3409. PMID 11248091 DOI: 10.1073/pnas.051632198  0.48
2001 Fahey JW, Zalcmann AT, Talalay P. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants Phytochemistry. 56: 5-51. PMID 11198818 DOI: 10.1016/S0031-9422(00)00316-2  0.48
2000 Talalay P. Chemoprotection against cancer by induction of Phase 2 enzymes Biofactors. 12: 5-11. PMID 11216505  0.48
2000 Foster CE, Bianchet MA, Talalay P, Faig M, Amzel LM. Structures of mammalian cytosolic quinone reductases Free Radical Biology and Medicine. 29: 241-245. PMID 11035252 DOI: 10.1016/S0891-5849(00)00299-9  0.48
2000 Dinkova-Kostova AT, Talalay P. Persuasive evidence that quinone reductase type 1 (DT diaphorase) protects cells against the toxicity of electrophiles and reactive forms of oxygen Free Radical Biology and Medicine. 29: 231-240. PMID 11035251 DOI: 10.1016/S0891-5849(00)00300-2  0.48
2000 Faig M, Bianchet MA, Talalay P, Chen S, Winski S, Ross D, Amzel LM. Structures of recombinant human and mouse NAD(P)H:quinone oxidoreductases: Species comparison and structural changes with substrate binding and release Proceedings of the National Academy of Sciences of the United States of America. 97: 3177-3182. PMID 10706635 DOI: 10.1073/pnas.050585797  0.48
1999 Bianchet MA, Foster C, Faig M, Talalay P, Amzel LM. Structure and mechanism of cytosolic quinone reductases Biochemical Society Transactions. 27: 610-615. PMID 10917652  0.48
1999 Fahey JW, Talalay P. Antioxidant functions of sulforaphane: A potent inducer of phase II detoxication enzymes Food and Chemical Toxicology. 37: 973-979. PMID 10541453 DOI: 10.1016/S0278-6915(99)00082-4  0.48
1999 Foster CE, Bianchet MA, Talalay P, Zhao Q, Amzel LM. Crystal structure of human quinone reductase type 2, a metalloflavoprotein Biochemistry. 38: 9881-9886. PMID 10433694 DOI: 10.1021/bi990799v  0.48
1999 Shikita M, Fahey JW, Golden TR, Holtzclaw WD, Talalay P. An unusual case of 'uncompetitive activation' by ascorbic acid: Purification and kinetic properties of a myrosinase from Raphanus sativus seedlings Biochemical Journal. 341: 725-732. PMID 10417337 DOI: 10.1042/0264-6021:3410725  0.48
1999 Dinkova-Kostova AT, Talalay P. Relation of structure of curcumin analogs to their potencies as inducers of Phase 2 detoxification enzymes Carcinogenesis. 20: 911-914. PMID 10334211  0.48
1998 Shapiro TA, Fahey JW, Wade KL, Stephenson KK, Talalay P. Human metabolism and excretion of cancer chemoprotective glucosinolates and isothiocyanates of cruciferous vegetables Cancer Epidemiology Biomarkers and Prevention. 7: 1091-1100. PMID 9865427  0.48
1998 Dinkova-Kostova AT, Abeygunawardana C, Talalay P. Chemoprotective properties of phenylpropenoids, bis(benzylidene)cycloalkanones, and related Michael reaction acceptors: Correlation of potencies as phase 2 enzyme inducers and radical scavengers Journal of Medicinal Chemistry. 41: 5287-5296. PMID 9857096 DOI: 10.1021/jm980424s  0.48
1998 Zhang Y, Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes Cancer Research. 58: 4632-4639. PMID 9788615  0.48
1998 Fahey JW, Stephenson KK, Talalay P. Glucosinolates, Myrosinase, and Isothiocyanates: Three Reasons for Eating Brassica Vegetables Acs Symposium Series. 701: 16-22.  0.48
1997 Fahey JW, Zhang Y, Talalay P. Broccoli sprouts: An exceptionally rich source of inducers of enzymes that protect against chemical carcinogens Proceedings of the National Academy of Sciences of the United States of America. 94: 10367-10372. PMID 9294217 DOI: 10.1073/pnas.94.19.10367  0.48
1997 Zhao Q, Yang XL, Holtzclaw WD, Talalay P. Unexpected genetic and structural relationships of a long-forgotten flavoenzyme to NAD(P)H:quinone reductase (DT-diaphorase) Proceedings of the National Academy of Sciences of the United States of America. 94: 1669-1674. PMID 9050836 DOI: 10.1073/pnas.94.5.1669  0.48
1997 Van Houten KA, Zhao O, Talalay P. Kinetics, mechanism and inhibition of human quinone reductase type-2 (HQR2) Faseb Journal. 11: A898.  0.48
1996 Talalay P, Zhang Y. Chemoprotection against cancer by isothiocyanates and glucosinolates. Biochemical Society Transactions. 24: 806-10. PMID 8878852  0.48
1996 Prestera T, Fahey JW, Holtzclaw WD, Abeygunawardana C, Kachinski JL, Talalay P. Comprehensive chromatographic and spectroscopic methods for the separation and identification of intact glucosinolates. Analytical Biochemistry. 239: 168-79. PMID 8811902 DOI: 10.1006/abio.1996.0312  0.48
1996 Zhang Y, Wade KL, Prestera T, Talalay P. Quantitative determination of isothiocyanates, dithiocarbamates, carbon disulfide, and related thiocarbonyl compounds by cyclocondensation with 1,2-benzenedithiol. Analytical Biochemistry. 239: 160-7. PMID 8811900 DOI: 10.1006/abio.1996.0311  0.48
1996 Zhao Q, Abeygunawardana C, Talalay P, Mildvan AS. NMR evidence for the participation of a low-barrier hydrogen bond in the mechanism of delta 5-3-ketosteroid isomerase. Proceedings of the National Academy of Sciences of the United States of America. 93: 8220-4. PMID 8710850 DOI: 10.1073/pnas.93.16.8220  0.48
1995 Prestera T, Talalay P, Alam J, Ahn YI, Lee PJ, Choi AM. Parallel induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements (ARE). Molecular Medicine (Cambridge, Mass.). 1: 827-37. PMID 8612205  0.48
1995 Talalay P, Fahey JW, Holtzclaw WD, Prestera T, Zhang Y. Chemoprotection against cancer by phase 2 enzyme induction. Toxicology Letters. 82: 173-9. PMID 8597048 DOI: 10.1016/0378-4274(95)03553-2  0.48
1995 Zhang Y, Kolm RH, Mannervik B, Talalay P. Reversible conjugation of isothiocyanates with glutathione catalyzed by human glutathione transferases. Biochemical and Biophysical Research Communications. 206: 748-55. PMID 7826396 DOI: 10.1006/bbrc.1995.1106  0.48
1995 Zhao Q, Mildvan AS, Talalay P. Enzymatic and nonenzymatic polarizations of alpha,beta-unsaturated ketosteroids and phenolic steroids. Implications for the roles of hydrogen bonding in the catalytic mechanism of delta 5-3-ketosteroid isomerase. Biochemistry. 34: 426-34. PMID 7819234  0.48
1995 Zhao Q, Li YK, Mildvan AS, Talalay P. Ultraviolet spectroscopic evidence for decreased motion of the active site tyrosine residue of delta 5-3-ketosteroid isomerase by steroid binding. Biochemistry. 34: 6562-72. PMID 7756287  0.48
1995 Putzer RR, Zhang Y, Prestera T, Holtzclaw WD, Wade KL, Talalay P. Mercurials and dimercaptans: synergism in the induction of chemoprotective enzymes. Chemical Research in Toxicology. 8: 103-10. PMID 7703353  0.48
1995 Prestera T, Talalay P. Electrophile and antioxidant regulation of enzymes that detoxify carcinogens. Proceedings of the National Academy of Sciences of the United States of America. 92: 8965-9. PMID 7568053 DOI: 10.1073/pnas.92.19.8965  0.48
1995 Li R, Bianchet MA, Talalay P, Amzel LM. The three-dimensional structure of NAD(P)H:quinone reductase, a flavoprotein involved in cancer chemoprotection and chemotherapy: mechanism of the two-electron reduction. Proceedings of the National Academy of Sciences of the United States of America. 92: 8846-50. PMID 7568029  0.48
1995 Kolm RH, Danielson UH, Zhang Y, Talalay P, Mannervik B. Isothiocyanates as substrates for human glutathione transferases: structure-activity studies. The Biochemical Journal. 311: 453-9. PMID 7487881  0.48
1994 Egner PA, Kensler TW, Prestera T, Talalay P, Libby AH, Joyner HH, Curphey TJ. Regulation of phase 2 enzyme induction by oltipraz and other dithiolethiones. Carcinogenesis. 15: 177-81. PMID 8313505  0.48
1994 Posner GH, Cho CG, Green JV, Zhang Y, Talalay P. Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxication enzymes. Journal of Medicinal Chemistry. 37: 170-6. PMID 8289191  0.48
1994 Zhang Y, Kensler TW, Cho CG, Posner GH, Talalay P. Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates. Proceedings of the National Academy of Sciences of the United States of America. 91: 3147-50. PMID 8159717  0.48
1994 Zhang Y, Talalay P. Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms. Cancer Research. 54: 1976s-1981s. PMID 8137323  0.48
1994 Wu P, Li YK, Talalay P, Brand L. Characterization of the three tyrosine residues of delta 5-3-ketosteroid isomerase by time-resolved fluorescence and circular dichroism. Biochemistry. 33: 7415-22. PMID 8003507  0.48
1994 Chen S, Clarke PE, Martino PA, Deng PS, Yeh CH, Lee TD, Prochaska HJ, Talalay P. Mouse liver NAD(P)H:quinone acceptor oxidoreductase: protein sequence analysis by tandem mass spectrometry, cDNA cloning, expression in Escherichia coli, and enzyme activity analysis. Protein Science : a Publication of the Protein Society. 3: 1296-304. PMID 7527260 DOI: 10.1002/pro.5560030816  0.48
1993 Li YK, Kuliopulos A, Mildvan AS, Talalay P. Environments and mechanistic roles of the tyrosine residues of delta 5-3-ketosteroid isomerase. Biochemistry. 32: 1816-24. PMID 8439542  0.48
1993 Prestera T, Holtzclaw WD, Zhang Y, Talalay P. Chemical and molecular regulation of enzymes that detoxify carcinogens. Proceedings of the National Academy of Sciences of the United States of America. 90: 2965-9. PMID 8385353  0.48
1993 Prestera T, Zhang Y, Spencer SR, Wilczak CA, Talalay P. The electrophile counterattack response: protection against neoplasia and toxicity. Advances in Enzyme Regulation. 33: 281-96. PMID 8356913 DOI: 10.1016/0065-2571(93)90024-8  0.48
1993 Kensler TW, Davidson NE, Groopman JD, Roebuck BD, Prochaska HJ, Talalay P. Chemoprotection by inducers of electrophile detoxication enzymes. Basic Life Sciences. 61: 127-36. PMID 8304925  0.48
1992 Prestera T, Prochaska HJ, Talalay P. Inhibition of NAD(P)H:(quinone-acceptor) oxidoreductase by cibacron blue and related anthraquinone dyes: a structure-activity study. Biochemistry. 31: 824-33. PMID 1731940  0.48
1992 McClellan DA, Talalay P. M.D.-Ph.D. training at the Johns Hopkins University School of Medicine, 1962-1991. Academic Medicine : Journal of the Association of American Medical Colleges. 67: 36-41. PMID 1729993  0.48
1992 Zhang Y, Talalay P, Cho CG, Posner GH. A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure. Proceedings of the National Academy of Sciences of the United States of America. 89: 2399-403. PMID 1549603  0.48
1992 Prochaska HJ, Santamaria AB, Talalay P. Rapid detection of inducers of enzymes that protect against carcinogens. Proceedings of the National Academy of Sciences of the United States of America. 89: 2394-8. PMID 1549602  0.48
1992 Zhang Y, Cho CG, Posner GH, Talalay P. Spectroscopic quantitation of organic isothiocyanates by cyclocondensation with vicinal dithiols. Analytical Biochemistry. 205: 100-7. PMID 1443546 DOI: 10.1016/0003-2697(92)90585-U  0.48
1992 Murnaghan JH, Talalay P. H. H. Dale's account of the standardization of insulin. Bulletin of the History of Medicine. 66: 440-50. PMID 1392508  0.48
1992 Talalay P, McClellan DA. Questioning public funding of M.D.-Ph.D. programs Academic Medicine. 67: 316.  0.48
1991 Xue LA, Kuliopulos A, Mildvan AS, Talalay P. Catalytic mechanism of an active-site mutant (D38N) of delta 5-3-ketosteroid isomerase. Direct spectroscopic evidence for dienol intermediates. Biochemistry. 30: 4991-7. PMID 2036366  0.48
1991 Spencer SR, Xue LA, Klenz EM, Talalay P. The potency of inducers of NAD(P)H:(quinone-acceptor) oxidoreductase parallels their efficiency as substrates for glutathione transferases. Structural and electronic correlations. The Biochemical Journal. 273: 711-7. PMID 1900000  0.48
1990 Kuliopulos A, Talalay P, Mildvan AS. Combined effects of two mutations of catalytic residues on the ketosteroid isomerase reaction. Biochemistry. 29: 10271-80. PMID 2271654  0.48
1990 Talalay P, Prochaska HJ, Spencer SR. Regulation of enzymes that detoxify the electrophilic forms of chemical carcinogens. Princess Takamatsu Symposia. 21: 177-87. PMID 2134677  0.48
1990 Spencer SR, Wilczak CA, Talalay P. Induction of glutathione transferases and NAD(P)H:quinone reductase by fumaric acid derivatives in rodent cells and tissues. Cancer Research. 50: 7871-5. PMID 2123743  0.48
1989 Kuliopulos A, Mildvan AS, Shortle D, Talalay P. Kinetic and ultraviolet spectroscopic studies of active-site mutants of delta 5-3-ketosteroid isomerase. Biochemistry. 28: 149-59. PMID 2706241  0.48
1989 Talalay P. Mechanisms of induction of enzymes that protect against chemical carcinogenesis Advances in Enzyme Regulation. 28: 237-250. PMID 2696344 DOI: 10.1016/0065-2571(89)90074-5  0.48
1989 Shantz LM, Talalay P, Gordon GB. Mechanism of inhibition of growth of 3T3-L1 fibroblasts and their differentiation to adipocytes by dehydroepiandrosterone and related steroids: Role of glucose-6-phosphate dehydrogenase Proceedings of the National Academy of Sciences of the United States of America. 86: 3852-3856. PMID 2524835  0.48
1988 Prochaska HJ, Talalay P. Regulatory mechanisms of monofunctional and bifunctional anticarcinogenic enzyme inducers in murine liver Cancer Research. 48: 4776-4782. PMID 3409219  0.48
1988 Talalay P, De Long MJ, Prochaska HJ. Identification of a common chemical signal regulating the induction of enzymes that protect against chemical carcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 85: 8261-8265. PMID 3141925  0.48
1987 Kuliopulos A, Shortle D, Talalay P. Isolation and sequencing of the gene encoding delta 5-3-ketosteroid isomerase of Pseudomonas testosteroni: overexpression of the protein Proceedings of the National Academy of Sciences of the United States of America. 84: 8893-8897. PMID 3480517  0.48
1987 Gordon GB, Shantz LM, Talalay P. Modulation of growth, differentiation and carcinogenesis by dehydroepiandrosterone Advances in Enzyme Regulation. 26: 355-382. PMID 2960133 DOI: 10.1016/0065-2571(87)90023-9  0.48
1987 Kuliopulos A, Westbrook EM, Talalay P, Mildvan AS. Positioning of a spin-labeled substrate analogue into the structure of delta 5-3-ketosteroid isomerase by combined kinetic, magnetic resonance, and X-ray diffraction methods. Biochemistry. 26: 3927-37. PMID 2888482  0.48
1987 De Long MJ, Santamaria AB, Talalay P. Role of cytochrome P1 in the induction of NAD(P)H:quinone reductase in a murine hepatoma cell line and its mutants Carcinogenesis. 8: 1549-1553. PMID 2820604 DOI: 10.1093/carcin/8.10.1549  0.48
1987 Prochaska HJ, Talalay P, Sies H. Direct protective effect of NAD(P)H:quinone reductase against menadione-induced chemiluminescence of postmitochondrial fractions of mouse liver Journal of Biological Chemistry. 262: 1931-1934. PMID 2434474  0.48
1986 Shapiro TA, Were JB, Talalay P, Bueding E, Rocco L, Danso K, Massof R, Green R, Mellits ED, Lietman PS. Clinical evaluation of amoscanate in healthy male volunteers American Journal of Tropical Medicine and Hygiene. 35: 945-953. PMID 3766854  0.48
1986 Lane MD, Talalay P. Albert Lester Lehninger 1917-1986 The Journal of Membrane Biology. 91: 194-197. PMID 3528502  0.48
1986 Boutin JA, Shikita M, Talalay P. Rat liver microsomal 3α-hydroxysteroid dehydrogenase and dihydrodiol dehydrogenase: Solubilization, separation and partial purification Biochemical and Biophysical Research Communications. 135: 795-801. PMID 3516149 DOI: 10.1016/0006-291X(86)90998-8  0.48
1986 Payne DW, Talalay P. A one-step enzymatic assay for the measurement of 17β-hydroxy- and 17-oxo-steroid profiles in biological samples Journal of Steroid Biochemistry. 25: 403-410. PMID 3464808 DOI: 10.1016/0022-4731(86)90253-0  0.48
1986 De Long MJ, Prochaska HJ, Talalay P. Induction of NAD(P)H:quinone reductase in murine hepatoma cells by phenolic antioxidants, azo dyes, and other chemoprotectors: A model system for the study of anticarcinogens Proceedings of the National Academy of Sciences of the United States of America. 83: 787-791. PMID 3080750  0.48
1986 Amzel LM, Bryant SH, Prochaska HJ, Talalay P. Preliminary crystallographic X-ray data for an NAD(P)H:quinone reductase from mouse liver Journal of Biological Chemistry. 261: 1379. PMID 3080425  0.48
1986 Gordon GB, Newitt JA, Shantz LM, Weng DE, Talalay P. Inhibition of the conversion of 3T3 fibroblast clones to adipocytes by dehydroepiandrosterone and related anticarcinogenic steroids Cancer Research. 46: 3389-3395. PMID 2939944  0.48
1986 Prochaska HJ, Talalay P. Purification and characterization of two isofunctional forms of NAD(P)H:quinone reductase from mouse liver Journal of Biological Chemistry. 261: 1372-1378. PMID 2418014  0.48
1985 Prochaska HJ, Bregman HS, De Long MJ, Talalay P. Specificity of induction of cancer protective enzymes by analogues of tert-butyl-4-hydroxyanisole (BHA) Biochemical Pharmacology. 34: 3909-3914. PMID 4062966 DOI: 10.1016/0006-2952(85)90443-5  0.48
1985 Prochaska HJ, De Long MJ, Talalay P. On the mechanisms of induction of cancer-protective enzymes: A unifying proposal Proceedings of the National Academy of Sciences of the United States of America. 82: 8232-8236. PMID 3934671  0.48
1985 De Long MJ, Prochaska H, Talalay P. Tissue-specific induction patterns of cancer-protective enzymes in mice by tert-butyl-4-hydroxyanisole and related substituted phenols Cancer Research. 45: 546-551. PMID 3917849  0.48
1985 Payne DW, Talalay P. Isolation of novel microbial 3α-, 3β-, and 17β-hydroxysteroid dehydrogenases. Purification, characterization, and analytical applications of a 17β-hydroxysteroid dehydrogenase from an alcaligenes sp Journal of Biological Chemistry. 260: 13648-13655. PMID 2997177  0.48
1985 De Long MJ, Prochaska HJ, Talalay P. Anticarcinogenic azo dyes and phenolic antioxidants induce NAD(P)H: Quinone reductase (QR) in Hepa lclc7 murine hepatoma cells Federation Proceedings. 44: No. 518.  0.48
1984 Penning TM, Mukharji I, Barrows S, Talalay P. Purification and properties of a 3α-hydroxysteroid dehydrogenase of rat liver cytosol and its inhibition by anti-inflammatory drugs Biochemical Journal. 222: 601-611. PMID 6435601  0.48
1984 Chou TC, Talalay P. Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors Advances in Enzyme Regulation. 22: 27-55. PMID 6382953 DOI: 10.1016/0065-2571(84)90007-4  0.48
1984 Wefers H, Komai T, Talalay P, Sies H. Protection against reactive oxygen species by NAD(P)H:quinone reductase induced by the dietary antioxidant butylated hydroxyanisole (BHA). Decreased hepatic low-level chemiluminescence during quinone redox cycling Febs Letters. 169: 63-66. PMID 6201394 DOI: 10.1016/0014-5793(84)80290-2  0.48
1984 Prochaska HJ, De Long M, Bregman H, Talalay P. Induction of glutathione transferases (GT) and nad(P)H:quinone reductase (QR) in mouse tissues by substituted phenols Federation Proceedings. 43: no. 1619.  0.48
1984 Ting-Chao Chou, Chou J, Talalay P. Conservation of laboratory animals by improved experimental design, generalized equations and computer analysis Federation Proceedings. 43: no. 1699.  0.48
1983 Pearson WR, Windle JJ, Morrow JF, Benson AM, Talalay P. Increased synthesis of glutathione S-transferases in response to anticarcinogenic antioxidants. Cloning and measurement of messenger RNA Journal of Biological Chemistry. 258: 2052-2062. PMID 6822548  0.48
1983 Penning TM, Talalay P. Inhibition of a major NAD(P)-linked oxidoreductase from rat liver cytosol by steroidal and nonsteroidal anti-inflammatory agents and by prostaglandins Proceedings of the National Academy of Sciences of the United States of America. 80: 4504-4508. PMID 6410393  0.48
1983 Chou TC, Talalay P. Analysis of combined drug effects: a new look at a very old problem Trends in Pharmacological Sciences. 4: 450-454. DOI: 10.1016/0165-6147(83)90490-X  0.48
1982 Shapiro TA, Talalay P. Schistosoma mansoni: Mechanisms in regulation of glycolysis Experimental Parasitology. 54: 379-390. PMID 7151946 DOI: 10.1016/0014-4894(82)90047-9  0.48
1982 Penning TM, Heller DN, Balasubramanian TM, Fenselau CC, Talalay P. Mass spectrometric studies of a modified active-site tetrapeptide from Δ-5-3-ketosteroid isomerase of Pseudomonas testosteroni Journal of Biological Chemistry. 257: 12589-12593. PMID 7130168  0.48
1982 Shapiro TA, Talalay P. Schistosoma mansoni: Inhibition of glucosephosphate isomerase and glycolysis by sugar phosphates Experimental Parasitology. 54: 196-201. PMID 7128716 DOI: 10.1016/0014-4894(82)90127-8  0.48
1982 Talalay P, Shikita M, Renaud M. Effects of the administration of androgenic and estrogenic steroids on 3α-hydroxysteroid dehydrogenase levels of the intact and castrated dog prostate Journal of Steroid Biochemistry. 16: 599-606. PMID 6954334 DOI: 10.1016/0022-4731(82)90093-0  0.48
1982 Payne DW, Shikita M, Talalay P. Enzymatic estimation of steroids in subpicomole quantities by hydroxysteroid dehydrogenases and nicotinamide nucleotide cycling Journal of Biological Chemistry. 257: 633-642. PMID 6947978  0.48
1982 Talalay P, Benson AM. Elevation of quinone reductase activity by anticarcinogenic antioxidants Advances in Enzyme Regulation. 20: 287-300. PMID 6180607 DOI: 10.1016/0065-2571(82)90021-8  0.48
1981 Penning TM, Covey DF, Talalay P. Inactivation of delta 5-3-oxo steroid isomerase with active-site-directed acetylenic steroids Biochemical Journal. 193: 217-227. PMID 7305923  0.48
1981 Penning TM, Covey DF, Talalay P. Irreversible inactivation of Δ5-3-ketosteroid isomerase of Pseudomonas testosteroni by acetylenic suicide substrates. Mechanism of formation and properties of the steroid-enzyme adduct Journal of Biological Chemistry. 256: 6842-6850. PMID 7240247  0.48
1981 Chou TC, Talalay P. Generalized equations for the analysis of inhibitions of Michaelis-Menten and higher-order kinetic systems with two or more mutually exclusive and nonexclusive inhibitors European Journal of Biochemistry. 115: 207-216. PMID 7227366  0.48
1981 Penning TM, Talalay P. Linkage of an acetylenic secosteroid suicide substrate to the active site of delta 5-3-ketosteroid isomerase. Isolation and characterization of a tetrapeptide Journal of Biological Chemistry. 256: 6851-6858. PMID 7016878  0.48
1980 Penning TM, Westbrook EM, Talalay P. On the number of steroid-binding sites of delta 5-3-oxosteroid isomerase European Journal of Biochemistry. 105: 461-469. PMID 7371643  0.48
1980 Benson AM, Hunkeler MJ, Talalay P. Increase of NAD(P)H:quinone reductase by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity Proceedings of the National Academy of Sciences of the United States of America. 77: 5216-5220. PMID 6933553  0.48
1979 Shikita M, Talalay P. Preparation of highly purified 3α- and 3β-hydroxysteroid dehydrogenases from Pseudomonas sp Analytical Biochemistry. 95: 286-292. PMID 495965 DOI: 10.1016/0003-2697(79)90218-5  0.48
1979 Sufrin JR, Coulter AW, Talalay P. Structural and conformational analogues of L-methionine as inhibitors of the enzymatic synthesis of S-adenosyl-L-methionine. IV. Further mono-, bi- and tricyclic amino acids Molecular Pharmacology. 15: 661-677. PMID 492150  0.48
1979 Bertolino A, Benson AM, Talalay P. Activation of delta5-3-ketosteroid isomerase of bovine adrenal microsomes by serum albumins. Biochemical and Biophysical Research Communications. 88: 1158-66. PMID 465075 DOI: 10.1016/0006-291X(79)91530-4  0.48
1979 Benson AM, Cha YN, Bueding E, Heine HS, Talalay P. Elevation of extrahepatic glutathione S-transferase and epoxide hydratase activities by 2(3)-tert-butyl-4-hydroxyanisole Cancer Research. 39: 2971-2977. PMID 455282  0.48
1979 Talalay P, Batzinger RP, Benson AM, Bueding E, Cha YN. Biochemical studies on the mechanisms by which dietary antioxidants suppress mutagenic activity Advances in Enzyme Regulation. 17: 23-36. PMID 393090 DOI: 10.1016/0065-2571(79)90006-2  0.48
1979 DeKlerk DP, Coffey DS, Ewing LL, McDermott IR, Reiner WG, Robinson CH, Scott WW, Strandberg JD, Talalay P, Walsh PC, Wheaton LG, Zirkin BR. Comparison of spontaneous and experimentally induced canine prostatic hyperplasia. The Journal of Clinical Investigation. 64: 842-9. PMID 89121 DOI: 10.1172/JCI109532  0.48
1978 Teicher BA, Koizumi N, Koreeda M, Shikita M, Talalay P. Biosynthesis of pregnenolone from cholesterol by mitochondrial enzymes of bovine adrenal cortex. The question of the participation of the 20(22)-olefins and 20, 22-epoxides of cholesterol. European Journal of Biochemistry / Febs. 91: 11-9. PMID 720329  0.48
1978 Teicher BA, Shikita M, Talalay P. Effects of adrenal steroid activator protein on the conversion of various 20- and 22-hydroxycholesterols to pregnenolone by adrenal mitochondrial enzymes Biochemical and Biophysical Research Communications. 83: 1436-1441. PMID 697872 DOI: 10.1016/0006-291X(78)91381-5  0.48
1978 Bueding E, Batzinger RP, Cha YN, Talalay P, Molineaux CJ. Protection from mutagenic effects of antischistosomal and other drugs Pharmacological Reviews. 30: 547-554. PMID 392546  0.48
1978 Benson AM, Batzinger RP, Ou SYL, Bueding E, Cha YN, Talalay P. Elevation of hepatic glutathione S-transferase activities and protection against mutagenic metabolites of benzo(a)pyrene by dietary antioxidants Cancer Research. 38: 4486-4495. PMID 363262  0.48
1977 Cornforth JW, Reichard SA, Talalay P, Carrell HL, Glusker JP. Determination of the absolute configuration at the sulfonium center of S-adenosylmethionine. Correlation with the absolute configuration of the diastereomeric S-carboxymethyl-(S)-methionine salts. Journal of the American Chemical Society. 99: 7292-7300. PMID 915153  0.48
1977 Batzold FH, Benson AM, Covey DF, Robinson CH, Talalay P. [51] Irreversible inhibitors of Δ 5-3-ketosteroid isomerase: Acetylenic and allenic 3-oxo-5,10-secosteroids Methods in Enzymology. 46: 461-468. PMID 909438 DOI: 10.1016/S0076-6879(77)46055-5  0.48
1977 Chou TC, Talalay P. A simple generalized equation for the analysis of multiple inhibitions of Michaelis-Menten kinetic systems Journal of Biological Chemistry. 252: 6438-6442. PMID 893418  0.48
1977 Benson AM, Talalay P, Keen JH, Jakoby WB. Relationship between the soluble glutathione dependent Δ5 3 ketosteroid isomerase and the glutathione S transferases of the liver Proceedings of the National Academy of Sciences of the United States of America. 74: 158-162. PMID 264670  0.48
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