Salih J. Wakil - Publications

Affiliations: 
Biochemistry and Molecular Biology Baylor College of Medicine, Houston, TX 
Area:
fatty acid metabolism and the metabolic syndrome
Website:
https://www.bcm.edu/departments/biochemistry-and-molecular-biology/?PMID=3794

180 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2012 Jung D, Abu-Elheiga L, Ayuzawa R, Gu Z, Shirakawa T, Fujiki Y, Nakatsuji N, Wakil SJ, Uesugi M. Mislocalization and inhibition of acetyl-CoA carboxylase 1 by a synthetic small molecule. The Biochemical Journal. 448: 409-16. PMID 23067267 DOI: 10.1042/BJ20121158  1
2012 Abu-Elheiga L, Wu H, Gu Z, Bressler R, Wakil SJ. Acetyl-CoA carboxylase 2-/- mutant mice are protected against fatty liver under high-fat, high-carbohydrate dietary and de novo lipogenic conditions. The Journal of Biological Chemistry. 287: 12578-88. PMID 22362781 DOI: 10.1074/jbc.M111.309559  1
2012 Abu-Elheiga L, Wu H, Gu Z, Wakil SJ. Reply to Hoehn et al.: Phenotypic discrepancies in acetyl-CoA carboxylase 2-deficient mice Journal of Biological Chemistry. 287: 15802. DOI: 10.1074/jbc.O112.362939  1
2011 Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA. Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid. Proceedings of the National Academy of Sciences of the United States of America. 108: 15757-62. PMID 21908709 DOI: 10.1073/pnas.1112334108  1
2011 Kamisuki S, Shirakawa T, Kugimiya A, Abu-Elheiga L, Choo HY, Yamada K, Shimogawa H, Wakil SJ, Uesugi M. Synthesis and evaluation of diarylthiazole derivatives that inhibit activation of sterol regulatory element-binding proteins. Journal of Medicinal Chemistry. 54: 4923-7. PMID 21561152 DOI: 10.1021/jm200304y  1
2009 Dong B, Saha PK, Huang W, Chen W, Abu-Elheiga LA, Wakil SJ, Stevens RD, Ilkayeva O, Newgard CB, Chan L, Moore DD. Activation of nuclear receptor CAR ameliorates diabetes and fatty liver disease. Proceedings of the National Academy of Sciences of the United States of America. 106: 18831-6. PMID 19850873 DOI: 10.1073/pnas.0909731106  1
2009 Mao J, Yang T, Gu Z, Heird WC, Finegold MJ, Lee B, Wakil SJ. aP2-Cre-mediated inactivation of acetyl-CoA carboxylase 1 causes growth retardation and reduced lipid accumulation in adipose tissues. Proceedings of the National Academy of Sciences of the United States of America. 106: 17576-81. PMID 19805143 DOI: 10.1073/pnas.0909055106  1
2009 Kamisuki S, Mao Q, Abu-Elheiga L, Gu Z, Kugimiya A, Kwon Y, Shinohara T, Kawazoe Y, Sato S, Asakura K, Choo HY, Sakai J, Wakil SJ, Uesugi M. A small molecule that blocks fat synthesis by inhibiting the activation of SREBP. Chemistry & Biology. 16: 882-92. PMID 19716478 DOI: 10.1016/j.chembiol.2009.07.007  1
2009 Wakil SJ, Abu-Elheiga LA. Fatty acid metabolism: target for metabolic syndrome. Journal of Lipid Research. 50: S138-43. PMID 19047759 DOI: 10.1194/jlr.R800079-JLR200  1
2008 Essop MF, Camp HS, Choi CS, Sharma S, Fryer RM, Reinhart GA, Guthrie PH, Bentebibel A, Gu Z, Shulman GI, Taegtmeyer H, Wakil SJ, Abu-Elheiga L. Reduced heart size and increased myocardial fuel substrate oxidation in ACC2 mutant mice. American Journal of Physiology. Heart and Circulatory Physiology. 295: H256-65. PMID 18487439 DOI: 10.1152/ajpheart.91489.2007  1
2007 Choi CS, Savage DB, Abu-Elheiga L, Liu ZX, Kim S, Kulkarni A, Distefano A, Hwang YJ, Reznick RM, Codella R, Zhang D, Cline GW, Wakil SJ, Shulman GI. Continuous fat oxidation in acetyl-CoA carboxylase 2 knockout mice increases total energy expenditure, reduces fat mass, and improves insulin sensitivity. Proceedings of the National Academy of Sciences of the United States of America. 104: 16480-5. PMID 17923673 DOI: 10.1073/pnas.0706794104  1
2006 Mao J, DeMayo FJ, Li H, Abu-Elheiga L, Gu Z, Shaikenov TE, Kordari P, Chirala SS, Heird WC, Wakil SJ. Liver-specific deletion of acetyl-CoA carboxylase 1 reduces hepatic triglyceride accumulation without affecting glucose homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 103: 8552-7. PMID 16717184 DOI: 10.1073/pnas.0603115103  1
2005 Abu-Elheiga L, Matzuk MM, Kordari P, Oh W, Shaikenov T, Gu Z, Wakil SJ. Mutant mice lacking acetyl-CoA carboxylase 1 are embryonically lethal. Proceedings of the National Academy of Sciences of the United States of America. 102: 12011-6. PMID 16103361 DOI: 10.1073/pnas.0505714102  1
2005 Oh W, Abu-Elheiga L, Kordari P, Gu Z, Shaikenov T, Chirala SS, Wakil SJ. Glucose and fat metabolism in adipose tissue of acetyl-CoA carboxylase 2 knockout mice. Proceedings of the National Academy of Sciences of the United States of America. 102: 1384-9. PMID 15677334 DOI: 10.1073/pnas.0409451102  1
2004 Chirala SS, Wakil SJ. Structure and function of animal fatty acid synthase. Lipids. 39: 1045-53. PMID 15726818 DOI: 10.1007/s11745-004-1329-9  1
2004 Chakravarty B, Gu Z, Chirala SS, Wakil SJ, Quiocho FA. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proceedings of the National Academy of Sciences of the United States of America. 101: 15567-72. PMID 15507492 DOI: 10.1073/pnas.0406901101  1
2004 Beinert H, Stumpf PK, Wakil SJ. David Ezra Green. Biographical Memoirs. National Academy of Sciences (U.S.). 84: 112-44. PMID 15484418  1
2004 Brink J, Ludtke SJ, Kong Y, Wakil SJ, Ma J, Chiu W. Experimental verification of conformational variation of human fatty acid synthase as predicted by normal mode analysis. Structure (London, England : 1993). 12: 185-91. PMID 14962379 DOI: 10.1016/j.str.2004.01.015  1
2003 Abu-Elheiga L, Oh W, Kordari P, Wakil SJ. Acetyl-CoA carboxylase 2 mutant mice are protected against obesity and diabetes induced by high-fat/high-carbohydrate diets. Proceedings of the National Academy of Sciences of the United States of America. 100: 10207-12. PMID 12920182 DOI: 10.1073/pnas.1733877100  1
2003 Mao J, Chirala SS, Wakil SJ. Human acetyl-CoA carboxylase 1 gene: presence of three promoters and heterogeneity at the 5'-untranslated mRNA region. Proceedings of the National Academy of Sciences of the United States of America. 100: 7515-20. PMID 12810950 DOI: 10.1073/pnas.1332670100  1
2003 Chirala SS, Chang H, Matzuk M, Abu-Elheiga L, Mao J, Mahon K, Finegold M, Wakil SJ. Fatty acid synthesis is essential in embryonic development: fatty acid synthase null mutants and most of the heterozygotes die in utero. Proceedings of the National Academy of Sciences of the United States of America. 100: 6358-63. PMID 12738878 DOI: 10.1073/pnas.0931394100  1
2003 Al-Feel W, DeMar JC, Wakil SJ. A Saccharomyces cerevisiae mutant strain defective in acetyl-CoA carboxylase arrests at the G2/M phase of the cell cycle. Proceedings of the National Academy of Sciences of the United States of America. 100: 3095-100. PMID 12626751 DOI: 10.1073/pnas.0538069100  1
2002 Ming D, Kong Y, Wakil SJ, Brink J, Ma J. Domain movements in human fatty acid synthase by quantized elastic deformational model. Proceedings of the National Academy of Sciences of the United States of America. 99: 7895-9. PMID 12060737 DOI: 10.1073/pnas.112222299  1
2002 Brink J, Ludtke SJ, Yang CY, Gu ZW, Wakil SJ, Chiu W. Quaternary structure of human fatty acid synthase by electron cryomicroscopy. Proceedings of the National Academy of Sciences of the United States of America. 99: 138-43. PMID 11756679 DOI: 10.1073/pnas.012589499  1
2001 Abu-Elheiga L, Matzuk MM, Abo-Hashema KA, Wakil SJ. Continuous fatty acid oxidation and reduced fat storage in mice lacking acetyl-CoA carboxylase 2. Science (New York, N.Y.). 291: 2613-6. PMID 11283375 DOI: 10.1126/science.1056843  1
2001 Chirala SS, Jayakumar A, Gu ZW, Wakil SJ. Human fatty acid synthase: role of interdomain in the formation of catalytically active synthase dimer. Proceedings of the National Academy of Sciences of the United States of America. 98: 3104-8. PMID 11248039 DOI: 10.1073/pnas.051635998  1
2000 Xiong S, Chirala SS, Wakil SJ. Sterol regulation of human fatty acid synthase promoter I requires nuclear factor-Y- and Sp-1-binding sites. Proceedings of the National Academy of Sciences of the United States of America. 97: 3948-53. PMID 10759542 DOI: 10.1073/pnas.040574197  1
2000 Abu-Elheiga L, Brinkley WR, Zhong L, Chirala SS, Woldegiorgis G, Wakil SJ. The subcellular localization of acetyl-CoA carboxylase 2. Proceedings of the National Academy of Sciences of the United States of America. 97: 1444-9. PMID 10677481 DOI: 10.1073/pnas.97.4.1444  1
1998 Xiong S, Chirala SS, Hsu MH, Wakil SJ. Identification of thyroid hormone response elements in the human fatty acid synthase promoter. Proceedings of the National Academy of Sciences of the United States of America. 95: 12260-5. PMID 9770474 DOI: 10.1073/pnas.95.21.12260  1
1997 Jayakumar A, Chirala SS, Wakil SJ. Human fatty acid synthase: assembling recombinant halves of the fatty acid synthase subunit protein reconstitutes enzyme activity. Proceedings of the National Academy of Sciences of the United States of America. 94: 12326-30. PMID 9356448 DOI: 10.1073/pnas.94.23.12326  1
1997 Chirala SS, Huang WY, Jayakumar A, Sakai K, Wakil SJ. Animal fatty acid synthase: functional mapping and cloning and expression of the domain I constituent activities. Proceedings of the National Academy of Sciences of the United States of America. 94: 5588-93. PMID 9159116 DOI: 10.1073/pnas.94.11.5588  1
1997 Abu-Elheiga L, Almarza-Ortega DB, Baldini A, Wakil SJ. Human acetyl-CoA carboxylase 2. Molecular cloning, characterization, chromosomal mapping, and evidence for two isoforms. The Journal of Biological Chemistry. 272: 10669-77. PMID 9099716 DOI: 10.1074/jbc.272.16.10669  1
1997 Al-Feel W, Wakil SJ. Construction and characterization of two conditional-lethal haploid yeast acetyl- CoA carboxylase mutants Faseb Journal. 11: A1389.  1
1996 Jayakumar A, Huang WY, Raetz B, Chirala SS, Wakil SJ. Cloning and expression of the multifunctional human fatty acid synthase and its subdomains in Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 93: 14509-14. PMID 8962082  1
1996 Hsu MH, Chirala SS, Wakil SJ. Human fatty-acid synthase gene. Evidence for the presence of two promoters and their functional interaction. The Journal of Biological Chemistry. 271: 13584-92. PMID 8662758 DOI: 10.1074/jbc.271.23.13584  1
1996 Hsu MH, Chirala SS, Wakil SJ. Human fatty acid synthase gene: Evidence for the presence of two promoters and their interactions Faseb Journal. 10: A1381.  1
1995 Abu-Elheiga L, Jayakumar A, Baldini A, Chirala SS, Wakil SJ. Human acetyl-CoA carboxylase: characterization, molecular cloning, and evidence for two isoforms. Proceedings of the National Academy of Sciences of the United States of America. 92: 4011-5. PMID 7732023  1
1995 Jayakumar A, Tai MH, Huang WY, al-Feel W, Hsu M, Abu-Elheiga L, Chirala SS, Wakil SJ. Human fatty acid synthase: properties and molecular cloning. Proceedings of the National Academy of Sciences of the United States of America. 92: 8695-9. PMID 7567999 DOI: 10.1073/pnas.92.19.8695  1
1994 Huang WY, Chirala SS, Wakil SJ. Amino-terminal blocking group and sequence of the animal fatty acid synthase. Archives of Biochemistry and Biophysics. 314: 45-9. PMID 7944406 DOI: 10.1006/abbi.1994.1410  1
1994 Mohamed AH, Huang WY, Huang W, Venkatachalam KV, Wakil SJ. Isolation and characterization of a novel acetyl-CoA carboxylase kinase from rat liver. The Journal of Biological Chemistry. 269: 6859-65. PMID 7907095  1
1994 Jayakumar A, Chirala SS, Chinault AC, Baldini A, Abu-Elheiga L, Wakil SJ. Isolation and chromosomal mapping of genomic clones encoding the human fatty acid synthase gene. Genomics. 23: 420-4. PMID 7835891 DOI: 10.1006/geno.1994.1518  1
1993 Tai MH, Chirala SS, Wakil SJ. Roles of Ser101, Asp236, and His237 in catalysis of thioesterase II and of the C-terminal region of the enzyme in its interaction with fatty acid synthase. Proceedings of the National Academy of Sciences of the United States of America. 90: 1852-6. PMID 8446599  1
1992 Stoops JK, Kolodziej SJ, Schroeter JP, Bretaudiere JP, Wakil SJ. Structure-function relationships of the yeast fatty acid synthase: negative-stain, cryo-electron microscopy, and image analysis studies of the end views of the structure. Proceedings of the National Academy of Sciences of the United States of America. 89: 6585-9. PMID 1631160  1
1992 Al-Feel W, Chirala SS, Wakil SJ. Cloning of the yeast FAS3 gene and primary structure of yeast acetyl-CoA carboxylase. Proceedings of the National Academy of Sciences of the United States of America. 89: 4534-8. PMID 1350093 DOI: 10.1073/pnas.89.10.4534  1
1991 Pazirandeh M, Chirala SS, Wakil SJ. Site-directed mutagenesis studies on the recombinant thioesterase domain of chicken fatty acid synthase expressed in Escherichia coli. The Journal of Biological Chemistry. 266: 20946-52. PMID 1939144  1
1990 Stoops JK, Singh N, Wakil SJ. The yeast fatty acid synthase. Pathway for transfer of the acetyl group from coenzyme A to the Cys-SH of the condensation site. The Journal of Biological Chemistry. 265: 16971-7. PMID 2211602  1
1990 Mabrouk GM, Helmy IM, Thampy KG, Wakil SJ. Acute hormonal control of acetyl-CoA carboxylase. The roles of insulin, glucagon, and epinephrine. The Journal of Biological Chemistry. 265: 6330-8. PMID 1969410  1
1989 Chirala SS, Kasturi R, Pazirandeh M, Stolow DT, Huang WY, Wakil SJ. A novel cDNA extension procedure. Isolation of chicken fatty acid synthase cDNA clones. The Journal of Biological Chemistry. 264: 3750-7. PMID 2917973  1
1989 Pazirandeh M, Chirala SS, Huang WY, Wakil SJ. Characterization of recombinant thioesterase and acyl carrier protein domains of chicken fatty acid synthase expressed in Escherichia coli. The Journal of Biological Chemistry. 264: 18195-201. PMID 2681189  1
1989 Wakil SJ. Fatty acid synthase, a proficient multifunctional enzyme. Biochemistry. 28: 4523-30. PMID 2669958  1
1989 Huang WY, Stoops JK, Wakil SJ. Complete amino acid sequence of chicken liver acyl carrier protein derived from the fatty acid synthase. Archives of Biochemistry and Biophysics. 270: 92-8. PMID 2648999 DOI: 10.1016/0003-9861(89)90011-8  1
1988 Kasturi R, Chirala S, Pazirandeh M, Wakil SJ. Characterization of a genomic and cDNA clone coding for the thioesterase domain and 3' noncoding region of the chicken liver fatty acid synthase gene. Biochemistry. 27: 7778-85. PMID 3207710  1
1988 Yang CY, Huang WY, Chirala S, Wakil SJ. Complete amino acid sequence of the thioesterase domain of chicken liver fatty acid synthase. Biochemistry. 27: 7773-7. PMID 3207709  1
1988 Tsukamoto Y, Wakil SJ. Isolation and mapping of the beta-hydroxyacyl dehydratase activity of chicken liver fatty acid synthase. The Journal of Biological Chemistry. 263: 16225-9. PMID 3182791  1
1988 Thampy KG, Huang WY, Wakil SJ. A rapid purification method for rat liver pyruvate carboxylase and amino acid sequence analyses of NH2-terminal and biotin peptide. Archives of Biochemistry and Biophysics. 266: 270-6. PMID 3178228 DOI: 10.1016/0003-9861(88)90258-5  1
1988 Mohamed AH, Chirala SS, Mody NH, Huang WY, Wakil SJ. Primary structure of the multifunctional alpha subunit protein of yeast fatty acid synthase derived from FAS2 gene sequence. The Journal of Biological Chemistry. 263: 12315-25. PMID 2900835  1
1988 Thampy KG, Wakil SJ. Regulation of acetyl-coenzyme A carboxylase. II. Effect of fasting and refeeding on the activity, phosphate content, and aggregation state of the enzyme. The Journal of Biological Chemistry. 263: 6454-8. PMID 2896194  1
1988 Thampy KG, Wakil SJ. Regulation of acetyl-coenzyme A carboxylase. I. Purification and properties of two forms of acetyl-coenzyme A carboxylase from rat liver. The Journal of Biological Chemistry. 263: 6447-53. PMID 2896193  1
1987 Stoops JK, Wakil SJ, Uberbacher EC, Bunick GJ. Small-angle neutron-scattering and electron microscope studies of the chicken liver fatty acid synthase. The Journal of Biological Chemistry. 262: 10246-51. PMID 3611059  1
1987 Chirala SS, Kuziora MA, Spector DM, Wakil SJ. Complementation of mutations and nucleotide sequence of FAS1 gene encoding beta subunit of yeast fatty acid synthase. The Journal of Biological Chemistry. 262: 4231-40. PMID 3031066  1
1986 Chirala SS, Wakil SJ. Radio-labeling of the PstI restriction fragments and improvement in the sequencing procedure. Gene. 47: 297-300. PMID 3030892 DOI: 10.1016/0378-1119(86)90073-9  1
1986 Wakil SJ. The relationship between structure and function for and the regulation of the enzymes of fatty acid synthesis. Annals of the New York Academy of Sciences. 478: 203-19. PMID 2879500  1
1985 Singh N, Wakil SJ, Stoops JK. Yeast fatty acid synthase: structure to function relationship. Biochemistry. 24: 6598-602. PMID 3910094  1
1985 Singh N, Wakil SJ, Stoops JK. The development and application of a novel chromophoric substrate for investigation of the mechanism of yeast fatty acid synthase. Biochemical and Biophysical Research Communications. 131: 786-92. PMID 3902014 DOI: 10.1016/0006-291X(85)91308-7  1
1985 Thampy KG, Wakil SJ. Activation of acetyl-CoA carboxylase. Purification and properties of a Mn2+-dependent phosphatase. The Journal of Biological Chemistry. 260: 6318-23. PMID 2860106  1
1985 Thampy g. K, Wakil SJ. Activation of acetyl-CoA carboxylase by a Mn2+ dependent phosphatase Federation Proceedings. 44: no. 2640.  1
1985 Spector DM, Kuziora MA, Wakil SJ. DNA sequence of the β-subunit gene of yeast fatty acid synthase Federation Proceedings. 44: No. 7025.  1
1984 Singh N, Wakil SJ, Stoops JK. On the question of half- or full-site reactivity of animal fatty acid synthetase. The Journal of Biological Chemistry. 259: 3605-11. PMID 6706971  1
1984 Yang CY, Wakil SJ. Separation of dimethylaminoazobenzenethiohydantoin amino acids by high-performance liquid chromatography at low picomole concentrations. Analytical Biochemistry. 137: 54-7. PMID 6428264 DOI: 10.1016/0003-2697(84)90345-2  1
1984 Kasturi R, Joshi VC, Wakil SJ. Colchicine inhibition of insulin induction of stearoyl-CoA desaturase and fatty acid synthetase in cultured avian liver explants. Archives of Biochemistry and Biophysics. 233: 530-9. PMID 6148915 DOI: 10.1016/0003-9861(84)90476-4  1
1984 Thampy KG, Wakil SJ. Activation and dephosphorylation of acetyl-CoA carboxylase Federation Proceedings. 43: no. 2198.  1
1983 Kasturi R, Wakil SJ. Increased synthesis and accumulation of phospholipids during differentiation of 3T3-L1 cells into adipocytes. The Journal of Biological Chemistry. 258: 3559-64. PMID 6833214  1
1983 Tsukamoto Y, Wong H, Mattick JS, Wakil SJ. The architecture of the animal fatty acid synthetase complex. IV. Mapping of active centers and model for the mechanism of action. The Journal of Biological Chemistry. 258: 15312-22. PMID 6654914  1
1983 Mattick JS, Nickless J, Mizugaki M, Yang CY, Uchiyama S, Wakil SJ. The architecture of the animal fatty acid synthetase. II. Separation of the core and thioesterase functions and determination of the N-C orientation of the subunit. The Journal of Biological Chemistry. 258: 15300-4. PMID 6654913  1
1983 Stoops JK, Henry SJ, Wakil SJ. The arrangement and role of some of the amino acid residues in the beta-ketoacyl synthetase site of chicken liver fatty acid synthetase. The Journal of Biological Chemistry. 258: 12482-6. PMID 6630195  1
1983 Shoukry S, Stoops JK, Wakil SJ. Inactivation of yeast fatty acid synthetase by modifying the beta-ketoacyl reductase active lysine residue with pyridoxal 5'-phosphate. Archives of Biochemistry and Biophysics. 226: 224-30. PMID 6416172 DOI: 10.1016/0003-9861(83)90288-6  1
1983 Wong H, Mattick JS, Wakil SJ. The architecture of the animal fatty acid synthetase. III. Isolation and characterization of beta-ketoacyl reductase. The Journal of Biological Chemistry. 258: 15305-11. PMID 6361031  1
1983 Mattick JS, Tsukamoto Y, Nickless J, Wakil SJ. The architecture of the animal fatty acid synthetase. I. Proteolytic dissection and peptide mapping. The Journal of Biological Chemistry. 258: 15291-9. PMID 6361030  1
1983 Kuziora MA, Chalmers JH, Douglas MG, Hitzeman RA, Mattick JS, Wakil SJ. Molecular cloning of fatty acid synthetase genes from Saccharomyces cerevisiae. The Journal of Biological Chemistry. 258: 11648-53. PMID 6311818  1
1983 Wakil SJ, Stoops JK, Joshi VC. Fatty acid synthesis and its regulation. Annual Review of Biochemistry. 52: 537-79. PMID 6137188 DOI: 10.1146/annurev.bi.52.070183.002541  1
1983 Wakil SJ, Stoops JK. 1 Structure and Mechanism of Fatty Acid Synthetase Enzymes. 16: 3-61. DOI: 10.1016/S1874-6047(08)60299-1  1
1982 Stoops JK, Wakil SJ. The reaction of chicken liver fatty acid synthetase with 5,5'-dithiobis(2-nitrobenzoic acid). Biochemical and Biophysical Research Communications. 104: 1018-24. PMID 7073722 DOI: 10.1016/0006-291X(82)91351-1  1
1982 Stoops JK, Wakil SJ. Animal fatty acid synthetase. Identification of the residues comprising the novel arrangement of the beta-ketoacyl synthetase site and their role in its cold inactivation. The Journal of Biological Chemistry. 257: 3230-5. PMID 7061475  1
1982 Aprahamian SA, Arslanian MJ, Wakil SJ. Comparative studies on the kinetic parameters and product analyses of chicken and rat liver and yeast fatty acid synthetase. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 71: 577-82. PMID 7044669 DOI: 10.1016/0305-0491(82)90465-5  1
1982 Calabro MA, Prasad MR, Wakil SJ, Joshi VC. Stearoyl-coenzyme A desaturase activity in the mammary gland and liver of lactating rats. Lipids. 17: 397-402. PMID 6125866 DOI: 10.1007/BF02535218  1
1982 Crisp JD, Wakil SJ. Chicken liver fatty acid synthetase: Proteolysis by subtilisin and isolation and properties of palmitoyl thioesterase Journal of Protein Chemistry. 1: 241-255. DOI: 10.1007/BF01025002  1
1981 Wakil SJ, Stoops JK, Mattick JS. The fatty acid synthetase-structure-function relationship and mechanism of palmitate synthesis. Cardiovascular Research Center Bulletin. 20: 1-23. PMID 7340934  1
1981 Stoops JK, Wakil SJ. The yeast fatty acid synthetase. Structure-function relationship and the role of the active cysteine-SH and pantetheine-SH. The Journal of Biological Chemistry. 256: 8364-70. PMID 7021548  1
1981 Mattick JS, Zehner ZE, Calabro MA, Wakil SJ. The isolation and characterization of fatty-acid synthetase mRNA from rat mammary gland. European Journal of Biochemistry / Febs. 114: 643-51. PMID 6113142  1
1981 Stoops JK, Wakil SJ. Animal fatty acid synthetase. A novel arrangement of the beta-ketoacyl synthetase sites comprising domains of the two subunits. The Journal of Biological Chemistry. 256: 5128-33. PMID 6112225  1
1980 Zehner ZE, Mattick JS, Stuart R, Wakil SJ. Goose fatty acid synthetase mRNA. The Journal of Biological Chemistry. 255: 9519-22. PMID 7430082  1
1980 Stoops JK, Wakil SJ. Yeast fatty acid synthetase: structure-function relationship and nature of the beta-ketoacyl synthetase site. Proceedings of the National Academy of Sciences of the United States of America. 77: 4544-8. PMID 7001460  1
1980 Sreekrishna K, Gunsberg S, Wakil SJ, Joshi VC. Interaction of the fluorescent analogue stearoyl-(1,N6)-etheno coenzyme A with chicken liver acetyl coenzyme A carboxylase. The Journal of Biological Chemistry. 255: 3348-51. PMID 6102564  1
1979 Stoops JK, Ross P, Arslanian MJ, Aune KC, Wakil SJ, Oliver RM. Physicochemical studies of the rat liver and adipose fatty acid synthetases. The Journal of Biological Chemistry. 254: 7418-26. PMID 457689  1
1979 Okuyama H, Saito M, Joshi VC, Gunsberg S, Wakil SJ. Regulation by temperature of the chain length of fatty acids in yeast. The Journal of Biological Chemistry. 254: 12281-4. PMID 387785  1
1978 Stoops JK, Arslanian MJ, Aune KC, Wakil SJ. Further evidence for the multifunctional enzyme characteristic of the fatty acid synthetases of animal tissues. Archives of Biochemistry and Biophysics. 188: 348-59. PMID 677903 DOI: 10.1016/S0003-9861(78)80019-8  1
1978 Joshi VC, Wakil SJ. Hormonal regulation of hepatic fatty acid synthetase in chick embryo. Role of insulin. The Journal of Biological Chemistry. 253: 2120-5. PMID 416024  1
1978 Stoops JK, Wakil SJ. The isolation of the two subunits of yeast fatty acid synthetase. Biochemical and Biophysical Research Communications. 84: 225-31. PMID 365179 DOI: 10.1016/0006-291X(78)90286-3  1
1978 Stoops JK, Awad ES, Arslanian MJ, Gunsberg S, Wakil SJ, Oliver RM. Studies on the yeast fatty acid synthetase. Subunit composition and structural organization of a large multifunctional enzyme complex. The Journal of Biological Chemistry. 253: 4464-75. PMID 350874  1
1978 Joshi VC, Wakil SJ. Hormonal induction of fatty acid synthetase in chick embryo involves regulation of the translatable messenger RNA for the enzyme Federation Proceedings. 37: No. 2873.  1
1977 Zehner ZE, Joshi VC, Wakil SJ. Regulation of fatty acid synthetase in perinatal chicks. Identification of polysomes synthesizing fatty acid synthetase. The Journal of Biological Chemistry. 252: 7015-22. PMID 332686  1
1977 Wilson AC, Murtadha M, Wakil SJ. Fatty acid synthesis in aorta. Isolation of fatty acid synthetase from chicken aorta. Atherosclerosis. 26: 103-15. PMID 13803 DOI: 10.1016/0021-9150(77)90145-9  1
1977 Joshi VC, Wilson AC, Wakil SJ. Assay for the terminal enzyme of the stearoyl coenzyme A desaturase system using chick embryo liver microsomes. Journal of Lipid Research. 18: 32-6. PMID 13132  1
1976 Arslanian MJ, Stoops JK, Oh YH, Wakil SJ. On the 4'-phosphopantetheine content of chicken and rat liver fatty acid synthetases. The Journal of Biological Chemistry. 251: 3194-6. PMID 1270444  1
1976 George-Nascimento C, Wakil SJ, Short SA, Kaback HR. Effect of lipids on the reconstitution of D-lactate oxidase in Escherichia coli membrane vesicles. The Journal of Biological Chemistry. 251: 6662-6. PMID 789373  1
1976 Okuyama H, Yamada K, Ikezawa H, Wakil SJ. Factors affecting the acyl selectivities of acyltransferases in Escherichia coli. The Journal of Biological Chemistry. 251: 2487-92. PMID 770468  1
1976 Wilson AC, Wakil SJ, Joshi VC. Induction of microsomal stearyl coenzyme A desaturase in the newly hatched chicks. Archives of Biochemistry and Biophysics. 173: 154-61. PMID 4026 DOI: 10.1016/0003-9861(76)90245-9  1
1975 Stoops JK, Arslanian MJ, Oh YH, Aune KC, Vanaman TC, Wakil SJ. Presence of two polypeptide chains comprising fatty acid synthetase. Proceedings of the National Academy of Sciences of the United States of America. 72: 1940-4. PMID 1098047 DOI: 10.1073/pnas.72.5.1940  1
1975 Arslanian MJ, Wakil SJ. Fatty acid synthase from chicken liver. Methods in Enzymology. 35: 59-65. PMID 235706 DOI: 10.1016/0076-6879(75)35138-0  1
1974 George Nascimento C, Zehner ZE, Wakil SJ. Assembly of lipids and proteins in Escherichia coli membranes Journal of Supramolecular and Cellular Biochemistry. 2: 646-669.  1
1973 Okuyama H, Wakil SJ. Positional specificities of acyl coenzyme A:glycerophosphate and acyl coenzyme A:monoacylglycerophosphate acyltransferases in Escherichia coli Journal of Biological Chemistry. 248: 5197-5205. PMID 4352195  1
1972 Crowfoot PD, Oka T, Esfahani M, Wakil SJ. Turnover of phospholipids in an unsaturated fatty acid auxotroph of Escherichia coli Journal of Bacteriology. 112: 1396-1407. PMID 4629658  1
1972 Wakil SJ, Esfahani M. The role of lipids in the structure and function of E. coli membrane Biochemical Society Symposia. 395-405. PMID 4614811  1
1972 Crowfoot PD, Esfahani M, Wakil SJ. Relation between protein synthesis and phospholipid synthesis and turnover in Escherichia coli Journal of Bacteriology. 112: 1408-1415. PMID 4565543  1
1972 Esfahani M, Crowfoot PD, Wakil SJ. Molecular organization of lipids in Escherichia coli membranes. II. Effect of phospholipids on succinic-ubiquinone reductase activity Journal of Biological Chemistry. 247: 7251-7256. PMID 4565080  1
1971 Esfahani M, Ioneda T, Wakil SJ. Studies on the control of fatty acid metabolism. 3. Incorporation of fatty acids into phospholipids and regulation of fatty acid synthetase of Escherichia coli Journal of Biological Chemistry. 246: 50-56. PMID 5541772  1
1971 Huxtable RJ, Wakil SJ. Comparative mitochondrial oxidation of fatty acids Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 239: 168-177. PMID 5119255 DOI: 10.1016/0005-2760(71)90163-9  1
1971 Esfahani M, Limbrick AR, Knutton S, Oka T, Wakil SJ. The molecular organization of lipids in the membrane of Escherichia coli: phase transitions Proceedings of the National Academy of Sciences of the United States of America. 68: 3180-3184. PMID 4943559  1
1971 Joshi VC, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XXVI. Purification and properties of malonyl-coenzyme A-Acyl carrier protein transacylase of Escherichia coli Archives of Biochemistry and Biophysics. 143: 493-505. PMID 4934182 DOI: 10.1016/0003-9861(71)90234-7  1
1971 Schulz H, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XXV. On the mechanism of beta-ketoacylacyl carrier protein reductase from Escherichia coli Journal of Biological Chemistry. 246: 1895-1901. PMID 4396098  1
1970 Schulz H, Wakil SJ. Reactions of hydroxylamine with acetoacetyl thioesters or ethyl acetoacetate Analytical Biochemistry. 37: 457-461. PMID 5476200 DOI: 10.1016/0003-2697(70)90073-4  1
1970 Weeks G, Wakil SJ. Studies on the control of fatty acid metabolism. II. The inhibition of fatty acid synthesis in Lactobacillus plantarum by exogenous fatty acid Journal of Biological Chemistry. 245: 1913-1921. PMID 5440835  1
1970 Joshi VC, Plate CA, Wakil SJ. Studies on the mechanism of fatty acid synthesis. 23. The acyl binding sites of the pigeon liver fatty acid synthetase Journal of Biological Chemistry. 245: 2857-2867. PMID 5423378  1
1970 Barnes EM, Wakil SJ, Swindell AC. Purification and properties of a palmityl thioesterase II from Escherichia coli Journal of Biological Chemistry. 245: 3122-3128. PMID 4914740  1
1970 Plate CA, Joshi VC, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XXIV. The acetyl- and malonyltransacylase activities of pigeon liver fatty acid synthetase Journal of Biological Chemistry. 245: 2868-2875. PMID 4912535  1
1970 Boone SC, Wakil SJ. In vitro synthesis of lignoceric and nervonic acids in mammalian liver and brain Biochemistry. 9: 1470-1479. PMID 4392137  1
1970 Holloway PW, Wakil SJ. Requirement for reduced diphosphopyridine nucleotide-cytochrome b5 reductase in stearly coenzyme A desaturation Journal of Biological Chemistry. 245: 1862-1865. PMID 4314600  1
1969 Esfahani M, Barnes EM, Wakil SJ. Control of fatty acid composition in phospholipids of Escherichia coli: response to fatty acid supplements in a fatty acid auxotroph Proceedings of the National Academy of Sciences of the United States of America. 64: 1057-1064. PMID 4905989  1
1969 Schulz H, Weeks G, Toomey RE, Shapiro M, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XXII. Salt activation of the fatty acid-synthesizing enzymes of Escherichia coli Journal of Biological Chemistry. 244: 6577-6583. PMID 4902887  1
1969 Weeks G, Shapiro M, Burns RO, Wakil SJ. Control of fatty acid metabolism. I. Induction of the enzymes of fatty acid oxidation in Escherichia coli Journal of Bacteriology. 97: 827-836. PMID 4886296  1
1969 Jones PD, Holloway PW, Peluffo RO, Wakil SJ. A requirement for lipids by the microsomal stearyl coenzyme A desaturase Journal of Biological Chemistry. 244: 744-754. PMID 4388795  1
1969 Weeks G, Wakil SJ. [12] Enoyl acyl carrier protein reductases from Escherichia Coli Methods in Enzymology. 14: 66-73. DOI: 10.1016/S0076-6879(69)14014-8  1
1968 Veeravagu P, Mizugaki M, Wakil SJ. A micromethod for identification of hydroxy acids Analytical Biochemistry. 23: 403-412. PMID 5658101  1
1968 Vanaman TC, Wakil SJ, Hill RL. The complete amino acid sequence of the acyl carrier protein of Escherichia coli Journal of Biological Chemistry. 243: 6420-6431. PMID 4882207  1
1968 Vanaman TC, Wakil SJ, Hill RL. The preparation of tryptic, peptic, thermolysin, and cyanogen bromide peptides from the acyl carrier protein of Escherichia coli Journal of Biological Chemistry. 243: 6409-6419. PMID 4882206  1
1968 Mizugaki M, Swindell AC, Wakil SJ. Intermediate- and long-chain β-hydroxyacyl-ACP dehydrases from E. coli fatty acid synthetase Biochemical and Biophysical Research Communications. 33: 520-527. PMID 4881058  1
1968 Barnes EM, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XIX. Preparation and general properties of palmityl thioesterase Journal of Biological Chemistry. 243: 2955-2962. PMID 4871199  1
1968 Weeks G, Wakil SJ. Studies on the mechanism of fatty acid synthesis. 18. Preparation and general properties of the enoyl acyl carrier protein reductases from Escherichia coli Journal of Biological Chemistry. 243: 1180-1189. PMID 4384650  1
1968 Plate CA, Joshi VC, Sedgwick B, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XXI. The role of fructose 1,6-diphosphate in the stimulation of the fatty acid synthetase from pigeon liver Journal of Biological Chemistry. 243: 5439-5445. PMID 4302786  1
1968 Mizugaki M, Weeks G, Toomey RE, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of beta-hydroxybutyryl acyl carrier protein dehydrase Journal of Biological Chemistry. 243: 3661-3670.  1
1967 Jones PD, Wakil SJ. A requirement for phospholipids by the microsomal reduced diphosphopyridine nucleotide-cytochrome c reductase Journal of Biological Chemistry. 242: 5267-5273. PMID 4294332  1
1966 Waite M, Wakil SJ. Studies on the mechanism of action of acetyl coenzyme A carboxylase. 3. Enzyme-bound 1'-N-carboxybiotin as the carboxylation intermediate Journal of Biological Chemistry. 241: 1909-1914. PMID 5945861  1
1966 Williamson IP, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XVII. Preparation and general properties of acetyl coenzyme A and malonyl coenzyme A-acyl carrier protein transacylases Journal of Biological Chemistry. 241: 2326-2332. PMID 5330116  1
1966 Toomey RE, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XVI. Preparation and general properties of acyl-malonyl acyl carrier protein-condensing enzyme from Escherichia coli Journal of Biological Chemistry. 241: 1159-1165. PMID 5327099  1
1966 Toomey RE, Wakil SJ. Studies on the mechanism of fatty acid synthesis XV. Preparation and general properties of β-ketoacyl acyl carrier protein reductase from Escherichia coli Biochimica Et Biophysica Acta (Bba)/Lipids and Lipid Metabolism. 116: 189-197. PMID 4381013  1
1966 Pugh EL, Sauer F, Waite M, Toomey RE, Wakil SJ. Studies on the mechanism of fatty acid synthesis. 13. The role of beta-hydroxy acids in the synthesis of palmitate and cis vaccenate by the Escherichia coli enzyme system Journal of Biological Chemistry. 241: 2635-2643. PMID 4380382  1
1966 Wakil SJ, Goldman JK, Williamson IP, Toomey RE. Stimulation of fatty acid biosynthesis by phosphorylated sugars Proceedings of the National Academy of Sciences of the United States of America. 55: 880-887. PMID 4379858  1
1965 Pugh EL, Wakil SJ. Studies on the mechanism of fatty acid synthesis. XIV. The prosthetic group of acyl carrier protein and the mode of its attachment to the protein Journal of Biological Chemistry. 240: 4727-4733. PMID 5321311  1
1964 SAUER F, PUGH EL, WAKIL SJ, DELANEY R, HILL RL. 2-MERCAPTOETHYLAMINE AND BETA-ALANINE AS COMPONENTS OF ACYL CARRIER Proceedings of the National Academy of Sciences of the United States Of. 52: 1360-1366. PMID 14243509  1
1964 HOLLOWAY PW, WAKIL SJ. SYNTHESIS OF FATTY ACIDS IN ANIMAL TISSUES. II. THE OCCURRENCE AND The Journal of Biological Chemistry. 239: 2489-2495. PMID 14235526  1
1964 WAKIL SJ, PUGH EL, SAUER F. THE MECHANISM OF FATTY ACID SYNTHESIS Proceedings of the National Academy of Sciences of the United States Of. 52: 106-114. PMID 14192647  1
1963 HARLAN WR, WAKIL SJ. SYNTHESIS OF FATTY ACIDS IN ANIMAL TISSUES. I. INCORPORATION OF The Journal of Biological Chemistry. 238: 3216-3223. PMID 14085364  1
1963 Holloway PW, Peluffo R, Wakil SJ. On the biosynthesis of dienoic fatty acid by animal tissues Biochemical and Biophysical Research Communications. 12: 300-304. PMID 14070333  1
1963 WAITE M, WAKIL SJ. Studies on the mechanism of action of acetyl coenzyme A carboxylase. I The Journal of Biological Chemistry. 238: 77-80. PMID 13998335  1
1963 Wakil SJ. [78] Malonyl coenzyme A Methods in Enzymology. 6: 540-544. DOI: 10.1016/0076-6879(63)06218-2  1
1962 WAKIL SJ. Lipid metabolism Annual Review of Biochemistry. 31: 369-406. PMID 14004468  1
1962 WAKIL SJ, BRESSLER R. Fatty acid metabolism and ketone body formation Metabolism: Clinical and Experimental. 11: 742-761. PMID 14004467  1
1962 WAITE M, WAKIL SJ. Studies on the mechanism of fatty acid synthesis. XII. Acetyl coenzyme A carboxylase The Journal of Biological Chemistry. 237: 2750-2757. PMID 14004432  1
1962 Wakil SJ. Enzymatic synthesis of fatty acids Comparative Biochemistry and Physiology. 4: 123-158. PMID 13998377  1
1962 Wakil SJ, Waite M. On the mechanism of action of enzyme-bound biotin Biochemical and Biophysical Research Communications. 9: 18-24. PMID 13998376  1
1962 Harlan WR, Wakil SJ. The pathways of synthesis of fatty acids by mitochondria Biochemical and Biophysical Research Communications. 8: 131-135. PMID 13904722  1
1962 BRESSLER R, WAKIL SJ. Studies on the mechanism of fatty acid synthesis. XI. The product of the reaction and the role of sulfhydryl groups in the synthesis of fatty acids The Journal of Biological Chemistry. 237: 1441-1448. PMID 13872874  1
1960 Wakil SJ, Gibson DM. Studies on the mechanism of fatty acid synthesis VIII. The participation of protein-bound biotin in the biosynthesis of fatty acids Bba - Biochimica Et Biophysica Acta. 41: 122-129.  1
1959 Wakil SJ, Ganguly J. On the mechanism of fatty acid synthesis [10] Journal of the American Chemical Society. 81: 2597-2598.  1
1959 Wakil SJ, Titchener EB, Gibson DM. Studies on the mechanism of fatty acid synthesis VI. Spectrophotometric assay and stoichiometry of fatty acid synthesis Bba - Biochimica Et Biophysica Acta. 34: 227-233.  1
1958 GIBSON DM, TITCHENER EB, WAKIL SJ. Studies on the mechanism of fatty acid synthesis. V. Bicarbonate requirement for the synthesis of long-chain fatty acids. Biochimica Et Biophysica Acta. 30: 376-83. PMID 13607455  1
1958 WAKIL SJ, TITCHENER EB, GIBSON DM. Evidence for the participation of biotin in the enzymic synthesis of fatty acids. Biochimica Et Biophysica Acta. 29: 225-6. PMID 13560478  1
1958 Gibson DM, Titchener EB, Wakil SJ. Requirement for bicarbonate in fatty acid synthesis [8] Journal of the American Chemical Society. 80: 2908.  1
1958 Wakil SJ. A malonic acid derivative as an intermediate in fatty acid synthesis [17] Journal of the American Chemical Society. 80: 6465.  1
1957 Porter JW, Wakil SJ, Tietz A, Jacob MI, Gibson DM. Studies on the mechanism of fatty acid synthesis II. Cofactor requirements of the soluble pigeon liver system Bba - Biochimica Et Biophysica Acta. 25: 35-41. PMID 13445712  1
1957 Gibson DM, Jacob MI, Porter JW, Tietz A, Wakil SJ. Biosynthesis of fatty acids by soluble enzyme fractions Bba - Biochimica Et Biophysica Acta. 23: 219-220. PMID 13412712  1
1957 Wakil SJ, Porter JW, Gibson DM. Studies on the mechanism of fatty acid synthesis. I. Preparation and purification of an enzyme system for reconstruction of fatty acid synthesis Bba - Biochimica Et Biophysica Acta. 24: 453-461.  1
1956 WAKIL SJ. Studies on the fatty acid oxidizing system of animal tissues. IX. Stereospecificity of unsaturated acyl CoA hydrase Biochimica Et Biophysica Acta. 19: 497-504. PMID 13315310  1
1955 Wakil SJ. d(-)β-hydroxybutyryl CoA dehydrogenase Bba - Biochimica Et Biophysica Acta. 18: 314-315. PMID 13276396  1
1954 WAKIL SJ, GREEN DE, MII S, MAHLER HR. Studies on the fatty acid oxidizing system of animal tissues. VI. beta-Hydroxyacyl coenzyme A dehydrogenase. The Journal of Biological Chemistry. 207: 631-8. PMID 13163047  1
1954 WAKIL SJ, MAHLER HR. Studies on the fatty acid oxidizing system of animal tissues. V. Unsaturated fatty acyl coenzyme A hydrase. The Journal of Biological Chemistry. 207: 125-32. PMID 13152086  1
1953 MAHLER HR, WAKIL SJ, BOCK RM. Studies on fatty acid oxidation. I. Enzymatic activation of fatty acids. The Journal of Biological Chemistry. 204: 453-68. PMID 13084616  1
1953 HANAHAN DJ, WAKIL SJ. Studies on absorption and metabolism of ergosterol-C. Archives of Biochemistry and Biophysics. 44: 150-8. PMID 13058363  1
1953 Hanahan DJ, Wakil SJ. The origin of some of the carbon atoms of the side chain of C14-ergosterol Journal of the American Chemical Society. 75: 273-275.  1
1953 Beinert H, Bock RM, Goldman DS, Green DE, Mahler HR, Mii S, Stansly PG, Wakil SJ. The reconstruction of the fatty acid oxidizing system of animal tissues [2] Journal of the American Chemical Society. 75: 4111-4112.  1
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