| Year |
Citation |
Score |
| 2023 |
Teixeira LR, Akella R, Humphreys JM, He H, Goldsmith EJ. Water and chloride as allosteric inhibitors in WNK kinase osmosensing. Biorxiv : the Preprint Server For Biology. PMID 37693587 DOI: 10.1101/2023.08.29.555411 |
0.334 |
|
| 2022 |
Rodriguez M, Kannangara A, Chlebowicz J, Akella R, He H, Tambar UK, Goldsmith EJ. Synthesis and Structural Characterization of Novel Trihalo-sulfone Inhibitors of WNK1. Acs Medicinal Chemistry Letters. 13: 1678-1684. PMID 36262391 DOI: 10.1021/acsmedchemlett.2c00216 |
0.35 |
|
| 2021 |
Akella R, Humphreys JM, Sekulski K, He H, Durbacz M, Chakravarthy S, Liwocha J, Mohammed ZJ, Brautigam CA, Goldsmith EJ. Osmosensing by WNK Kinases. Molecular Biology of the Cell. mbcE20010089. PMID 33689398 DOI: 10.1091/mbc.E20-01-0089 |
0.377 |
|
| 2021 |
Pleinis JM, Norrell L, Akella R, Humphreys JM, He H, Sun Q, Zhang F, Sosa-Pagan J, Morrison DE, Schellinger JN, Jackson LK, Goldsmith EJ, Rodan AR. WNKs are potassium-sensitive kinases. American Journal of Physiology. Cell Physiology. PMID 33439774 DOI: 10.1152/ajpcell.00456.2020 |
0.339 |
|
| 2020 |
Akella R, Drozdz MA, Humphreys JM, Jiou J, Durbacz MZ, Mohammed ZJ, He H, Liwocha J, Sekulski K, Goldsmith EJ. A phosphorylated intermediate in the activation of WNK kinases. Biochemistry. PMID 32314908 DOI: 10.1021/Acs.Biochem.0C00146 |
0.521 |
|
| 2020 |
Yesilkanal AE, Yang D, Tiwari P, Sabino AU, Lee J, Xie X, Sun S, Dann C, Steinberg E, Stuhlmiller T, Frankenberger C, Goldsmith E, Johnson GL, Ramos AF, Rosner M. Abstract 5038: Limited inhibition of multiple nodes in a driver network blocks metastasis Cancer Research. 80: 5038-5038. DOI: 10.1158/1538-7445.Am2020-5038 |
0.345 |
|
| 2019 |
Taylor CA, Cormier KW, Keenan SE, Earnest S, Stippec S, Wichaidit C, Juang YC, Wang J, Shvartsman SY, Goldsmith EJ, Cobb MH. Functional divergence caused by mutations in an energetic hotspot in ERK2. Proceedings of the National Academy of Sciences of the United States of America. PMID 31296562 DOI: 10.1073/pnas.1905015116 |
0.414 |
|
| 2019 |
Goldsmith EJ, Akella R, Durbacs M, Mohammed K. Inhibitors of WNK1 Acta Crystallographica Section A. 75. DOI: 10.1107/S0108767319099100 |
0.322 |
|
| 2018 |
Sun Q, Wu Y, Jonusaite S, Pleinis JM, Humphreys JM, He H, Schellinger JN, Akella R, Stenesen D, Krämer H, Goldsmith EJ, Rodan AR. Intracellular Chloride and Scaffold Protein Mo25 Cooperatively Regulate Transepithelial Ion Transport through WNK Signaling in the Malpighian Tubule. Journal of the American Society of Nephrology : Jasn. PMID 29602832 DOI: 10.1681/Asn.2017101091 |
0.31 |
|
| 2017 |
Jindal GA, Goyal Y, Humphreys JM, Yeung E, Tian K, Patterson VL, He H, Burdine RD, Shvartsman SY, Goldsmith EJ. How activating mutations affect MEK1 regulation and function. The Journal of Biological Chemistry. PMID 29018093 DOI: 10.1074/Jbc.C117.806067 |
0.492 |
|
| 2017 |
Goldsmith EJ, Akella R, Jiou J. Structural basis for activation of WNK kinases by hydrostatic pressure Acta Crystallographica Section A. 73. DOI: 10.1107/S0108767317096945 |
0.427 |
|
| 2016 |
Piala AT, Akella R, Potts MB, Dudics-Giagnocavo SA, He H, Wei S, White MA, Posner BA, Goldsmith EJ. Discovery of novel TAOK2 inhibitor scaffolds from high-throughput screening. Bioorganic & Medicinal Chemistry Letters. PMID 27426302 DOI: 10.1016/J.Bmcl.2016.07.016 |
0.42 |
|
| 2015 |
Taylor CA, Juang YC, Earnest S, Sengupta S, Goldsmith EJ, Cobb MH. Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK. Biochemistry. PMID 26208601 DOI: 10.1021/Acs.Biochem.5B00593 |
0.527 |
|
| 2014 |
Piala AT, Humphreys JM, Goldsmith EJ. MAP kinase modules: the excursion model and the steps that count. Biophysical Journal. 107: 2006-15. PMID 25418086 DOI: 10.1016/J.Bpj.2014.09.024 |
0.449 |
|
| 2014 |
Piala AT, Moon TM, Akella R, He H, Cobb MH, Goldsmith EJ. Chloride sensing by WNK1 involves inhibition of autophosphorylation. Science Signaling. 7: ra41. PMID 24803536 DOI: 10.1126/Scisignal.2005050 |
0.48 |
|
| 2013 |
Humphreys JM, Piala AT, Akella R, He H, Goldsmith EJ. Precisely ordered phosphorylation reactions in the p38 mitogen-activated protein (MAP) kinase cascade. The Journal of Biological Chemistry. 288: 23322-30. PMID 23744074 DOI: 10.1074/Jbc.M113.462101 |
0.449 |
|
| 2013 |
Moon TM, Correa F, Kinch LN, Piala AT, Gardner KH, Goldsmith EJ. Solution structure of the WNK1 autoinhibitory domain, a WNK-specific PF2 domain Journal of Molecular Biology. 425: 1245-1252. PMID 23376100 DOI: 10.1016/J.Jmb.2013.01.031 |
0.419 |
|
| 2011 |
Goldsmith EJ. Three-dimensional docking in the MAPK p38α. Science Signaling. 4: pe47. PMID 22375047 DOI: 10.1126/Scisignal.2002697 |
0.536 |
|
| 2011 |
Ahn YH, Yang Y, Gibbons DL, Creighton CJ, Yang F, Wistuba II, Lin W, Thilaganathan N, Alvarez CA, Roybal J, Goldsmith EJ, Tournier C, Kurie JM. Map2k4 functions as a tumor suppressor in lung adenocarcinoma and inhibits tumor cell invasion by decreasing peroxisome proliferator-activated receptor γ2 expression. Molecular and Cellular Biology. 31: 4270-85. PMID 21896780 DOI: 10.1128/Mcb.05562-11 |
0.358 |
|
| 2010 |
Akella R, Min X, Wu Q, Gardner KH, Goldsmith EJ. The third conformation of p38α MAP kinase observed in phosphorylated p38α and in solution Structure. 18: 1571-1578. PMID 21134636 DOI: 10.1016/J.Str.2010.09.015 |
0.517 |
|
| 2010 |
Goldsmith EJ, Min X, He H, Zhou T. Structural studies of MAP Kinase cascade components Methods in Molecular Biology (Clifton, N.J.). 661: 223-237. PMID 20811986 DOI: 10.1007/978-1-60761-795-2_13 |
0.478 |
|
| 2010 |
Deng X, Lee J, Michael AJ, Tomchick DR, Goldsmith EJ, Phillips MA. Evolution of substrate specificity within a diverse family of beta/alpha-barrel-fold basic amino acid decarboxylases: X-ray structure determination of enzymes with specificity for L-arginine and carboxynorspermidine. The Journal of Biological Chemistry. 285: 25708-19. PMID 20534592 DOI: 10.1074/Jbc.M110.121137 |
0.359 |
|
| 2009 |
Deng X, Gujjar R, El Mazouni F, Kaminsky W, Malmquist NA, Goldsmith EJ, Rathod PK, Phillips MA. Structural plasticity of malaria dihydroorotate dehydrogenase allows selective binding of diverse chemical scaffolds. The Journal of Biological Chemistry. 284: 26999-7009. PMID 19640844 DOI: 10.1074/Jbc.M109.028589 |
0.376 |
|
| 2009 |
Lee SJ, Cobb MH, Goldsmith EJ. Crystal structure of domain-swapped STE20 OSR1 kinase domain. Protein Science : a Publication of the Protein Society. 18: 304-13. PMID 19177573 DOI: 10.1002/Pro.27 |
0.486 |
|
| 2009 |
Min X, Akella R, He H, Humphreys JM, Tsutakawa SE, Lee SJ, Tainer JA, Cobb MH, Goldsmith EJ. The structure of the MAP2K MEK6 reveals an autoinhibitory dimer. Structure (London, England : 1993). 17: 96-104. PMID 19141286 DOI: 10.1016/J.Str.2008.11.007 |
0.567 |
|
| 2008 |
Hao YH, Wang Y, Burdette D, Mukherjee S, Keitany G, Goldsmith E, Orth K. Structural requirements for Yersinia YopJ inhibition of MAP kinase pathways. Plos One. 3: e1375. PMID 18167536 DOI: 10.1371/Journal.Pone.0001375 |
0.531 |
|
| 2008 |
Akella R, Moon TM, Goldsmith EJ. Unique MAP Kinase binding sites. Biochimica Et Biophysica Acta. 1784: 48-55. PMID 18068683 DOI: 10.1016/J.Bbapap.2007.09.016 |
0.464 |
|
| 2007 |
Goldsmith EJ, Akella R, Min X, Zhou T, Humphreys JM. Substrate and docking interactions in serine/threonine protein kinases. Chemical Reviews. 107: 5065-81. PMID 17949044 DOI: 10.1021/Cr068221W |
0.526 |
|
| 2007 |
Yazicioglu MN, Goad DL, Ranganathan A, Whitehurst AW, Goldsmith EJ, Cobb MH. Mutations in ERK2 binding sites affect nuclear entry. The Journal of Biological Chemistry. 282: 28759-67. PMID 17656361 DOI: 10.1074/Jbc.M703460200 |
0.419 |
|
| 2007 |
Lee J, Michael AJ, Martynowski D, Goldsmith EJ, Phillips MA. Phylogenetic diversity and the structural basis of substrate specificity in the beta/alpha-barrel fold basic amino acid decarboxylases. The Journal of Biological Chemistry. 282: 27115-25. PMID 17626020 DOI: 10.1074/Jbc.M704066200 |
0.36 |
|
| 2007 |
Shah R, Akella R, Goldsmith EJ, Phillips MA. X-ray structure of Paramecium bursaria Chlorella virus arginine decarboxylase: insight into the structural basis for substrate specificity. Biochemistry. 46: 2831-41. PMID 17305368 DOI: 10.1021/Bi6023447 |
0.39 |
|
| 2006 |
Wilsbacher JL, Juang YC, Khokhlatchev AV, Gallagher E, Binns D, Goldsmith EJ, Cobb MH. Characterization of mitogen-activated protein kinase (MAPK) dimers. Biochemistry. 45: 13175-82. PMID 17073439 DOI: 10.1021/Bi061041W |
0.504 |
|
| 2006 |
Lee SJ, Zhou T, Goldsmith EJ. Crystallization of MAP kinases. Methods (San Diego, Calif.). 40: 224-33. PMID 16829129 DOI: 10.1016/J.Ymeth.2006.05.003 |
0.491 |
|
| 2006 |
Zhou T, Sun L, Humphreys J, Goldsmith EJ. Docking interactions induce exposure of activation loop in the MAP kinase ERK2. Structure (London, England : 1993). 14: 1011-9. PMID 16765894 DOI: 10.1016/J.Str.2006.04.006 |
0.503 |
|
| 2006 |
Zhou TJ, Sun LG, Gao Y, Goldsmith EJ. Crystal structure of the MAP3K TAO2 kinase domain bound by an inhibitor staurosporine. Acta Biochimica Et Biophysica Sinica. 38: 385-92. PMID 16761096 DOI: 10.1111/J.1745-7270.2006.00173.X |
0.548 |
|
| 2006 |
Mukherjee S, Keitany G, Li Y, Wang Y, Ball HL, Goldsmith EJ, Orth K. Yersinia YopJ acetylates and inhibits kinase activation by blocking phosphorylation. Science (New York, N.Y.). 312: 1211-4. PMID 16728640 DOI: 10.1126/Science.1126867 |
0.485 |
|
| 2006 |
Zhou H, Zheng M, Chen J, Xie C, Kolatkar AR, Zarubin T, Ye Z, Akella R, Lin S, Goldsmith EJ, Han J. Determinants that control the specific interactions between TAB1 and p38alpha. Molecular and Cellular Biology. 26: 3824-34. PMID 16648477 DOI: 10.1128/Mcb.26.10.3824-3834.2006 |
0.515 |
|
| 2005 |
Lenertz LY, Lee BH, Min X, Xu BE, Wedin K, Earnest S, Goldsmith EJ, Cobb MH. Properties of WNK1 and implications for other family members. The Journal of Biological Chemistry. 280: 26653-8. PMID 15883153 DOI: 10.1074/Jbc.M502598200 |
0.464 |
|
| 2005 |
Xu BE, Lee BH, Min X, Lenertz L, Heise CJ, Stippec S, Goldsmith EJ, Cobb MH. WNK1: analysis of protein kinase structure, downstream targets, and potential roles in hypertension. Cell Research. 15: 6-10. PMID 15686619 DOI: 10.1038/Sj.Cr.7290256 |
0.453 |
|
| 2004 |
Jackson LK, Baldwin J, Akella R, Goldsmith EJ, Phillips MA. Multiple active site conformations revealed by distant site mutation in ornithine decarboxylase. Biochemistry. 43: 12990-9. PMID 15476392 DOI: 10.1021/Bi048933L |
0.422 |
|
| 2004 |
Zhou T, Raman M, Gao Y, Earnest S, Chen Z, Machius M, Cobb MH, Goldsmith EJ. Crystal structure of the TAO2 kinase domain: activation and specificity of a Ste20p MAP3K. Structure (London, England : 1993). 12: 1891-900. PMID 15458637 DOI: 10.1016/J.Str.2004.07.021 |
0.557 |
|
| 2004 |
Lee BH, Min X, Heise CJ, Xu BE, Chen S, Shu H, Luby-Phelps K, Goldsmith EJ, Cobb MH. WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding. Molecular Cell. 15: 741-51. PMID 15350218 DOI: 10.1016/J.Molcel.2004.07.018 |
0.425 |
|
| 2004 |
Min X, Lee BH, Cobb MH, Goldsmith EJ. Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension. Structure (London, England : 1993). 12: 1303-11. PMID 15242606 DOI: 10.1016/J.Str.2004.04.014 |
0.551 |
|
| 2004 |
Lee T, Hoofnagle AN, Kabuyama Y, Stroud J, Min X, Goldsmith EJ, Chen L, Resing KA, Ahn NG. Docking motif interactions in MAP kinases revealed by hydrogen exchange mass spectrometry. Molecular Cell. 14: 43-55. PMID 15068802 DOI: 10.1016/S1097-2765(04)00161-3 |
0.502 |
|
| 2004 |
Goldsmith EJ, Cobb MH, Chang CI. Structure of MAPKs. Methods in Molecular Biology (Clifton, N.J.). 250: 127-44. PMID 14755085 DOI: 10.1385/1-59259-671-1:127 |
0.366 |
|
| 2003 |
Bergstrom RC, Coombs GS, Ye S, Madison EL, Goldsmith EJ, Corey DR. Binding of nonphysiological protein and peptide substrates to proteases: differences between urokinase-type plasminogen activator and trypsin and contributions to the evolution of regulated proteolysis. Biochemistry. 42: 5395-402. PMID 12731881 DOI: 10.1021/Bi027417X |
0.375 |
|
| 2003 |
Jackson LK, Goldsmith EJ, Phillips MA. X-ray structure determination of Trypanosoma brucei ornithine decarboxylase bound to D-ornithine and to G418: insights into substrate binding and ODC conformational flexibility. The Journal of Biological Chemistry. 278: 22037-43. PMID 12672797 DOI: 10.1074/Jbc.M300188200 |
0.403 |
|
| 2002 |
Xu BE, Min X, Stippec S, Lee BH, Goldsmith EJ, Cobb MH. Regulation of WNK1 by an autoinhibitory domain and autophosphorylation. The Journal of Biological Chemistry. 277: 48456-62. PMID 12374799 DOI: 10.1074/Jbc.M207917200 |
0.488 |
|
| 2002 |
Goldsmith EJ, Chang CI. Another twist in helix C and a missing pocket. Structure (London, England : 1993). 10: 888-9. PMID 12121643 DOI: 10.1016/S0969-2126(02)00798-0 |
0.45 |
|
| 2002 |
Chang CI, Xu BE, Akella R, Cobb MH, Goldsmith EJ. Crystal structures of MAP kinase p38 complexed to the docking sites on its nuclear substrate MEF2A and activator MKK3b. Molecular Cell. 9: 1241-9. PMID 12086621 DOI: 10.1016/S1097-2765(02)00525-7 |
0.48 |
|
| 2002 |
Coleman DE, Rao GSJ, Goldsmith EJ, Cook PF, Harris BG. Crystal structure of the malic enzyme from Ascaris suum complexed with nicotinamide adenine dinucleotide at 2.3 Å resolution Biochemistry. 41: 6928-6938. PMID 12033925 DOI: 10.1021/Bi0255120 |
0.377 |
|
| 2001 |
Ye S, Goldsmith EJ. Serpins and other covalent protease inhibitors. Current Opinion in Structural Biology. 11: 740-745. PMID 11751056 DOI: 10.1016/S0959-440X(01)00275-5 |
0.371 |
|
| 2001 |
Ye S, Cech AL, Belmares R, Bergstrom RC, Tong Y, Corey DR, Kanost MR, Goldsmith EJ. The structure of a Michaelis serpin-protease complex. Nature Structural Biology. 8: 979-83. PMID 11685246 DOI: 10.1038/Nsb1101-979 |
0.425 |
|
| 2001 |
Hoofnagle AN, Resing KA, Goldsmith EJ, Ahn NG. Changes in protein conformational mobility upon activation of extracellular regulated protein kinase-2 as detected by hydrogen exchange Proceedings of the National Academy of Sciences of the United States of America. 98: 956-961. PMID 11158577 DOI: 10.1073/Pnas.98.3.956 |
0.468 |
|
| 2000 |
Jackson LK, Brooks HB, Osterman AL, Goldsmith EJ, Phillips MA. Altering the reaction specificity of eukaryotic ornithine decarboxylase. Biochemistry. 39: 11247-57. PMID 10985770 DOI: 10.1021/Bi001209S |
0.372 |
|
| 2000 |
Xu B, English JM, Wilsbacher JL, Stippec S, Goldsmith EJ, Cobb MH. WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II. The Journal of Biological Chemistry. 275: 16795-801. PMID 10828064 DOI: 10.1074/Jbc.275.22.16795 |
0.51 |
|
| 2000 |
Cobb MH, Goldsmith EJ. Dimerization in MAP-kinase signaling. Trends in Biochemical Sciences. 25: 7-9. PMID 10637602 DOI: 10.1016/S0968-0004(99)01508-X |
0.445 |
|
| 1999 |
Grishin NV, Osterman AL, Brooks HB, Phillips MA, Goldsmith EJ. X-ray structure of ornithine decarboxylase from Trypanosoma brucei: the native structure and the structure in complex with alpha-difluoromethylornithine. Biochemistry. 38: 15174-84. PMID 10563800 DOI: 10.1021/Bi9915115 |
0.378 |
|
| 1999 |
Li J, Wang Z, Canagarajah B, Jiang H, Kanost M, Goldsmith EJ. The structure of active serpin 1K from Manduca sexta. Structure (London, England : 1993). 7: 103-9. PMID 10368276 DOI: 10.1016/S0969-2126(99)80013-6 |
0.379 |
|
| 1999 |
Wilsbacher JL, Goldsmith EJ, Cobb MH. Phosphorylation of MAP kinases by MAP/ERK involves multiple regions of MAP kinases. The Journal of Biological Chemistry. 274: 16988-94. PMID 10358048 DOI: 10.1074/Jbc.274.24.16988 |
0.475 |
|
| 1998 |
Robinson MJ, Stippec SA, Goldsmith E, White MA, Cobb MH. A constitutively active and nuclear form of the MAP kinase ERK2 is sufficient for neurite outgrowth and cell transformation. Current Biology : Cb. 8: 1141-50. PMID 9799732 DOI: 10.1016/S0960-9822(07)00485-X |
0.462 |
|
| 1998 |
Wang Z, Canagarajah BJ, Boehm JC, Kassisà S, Cobb MH, Young PR, Abdel-Meguid S, Adams JL, Goldsmith EJ. Structural basis of inhibitor selectivity in MAP kinases. Structure (London, England : 1993). 6: 1117-28. PMID 9753691 DOI: 10.1016/S0969-2126(98)00113-0 |
0.482 |
|
| 1998 |
Gum RJ, McLaughlin MM, Kumar S, Wang Z, Bower MJ, Lee JC, Adams JL, Livi GP, Goldsmith EJ, Young PR. Acquisition of Sensitivity of Stress-activated Protein Kinases to the p38 Inhibitor, SB 203580, by Alteration of One or More Amino Acids within the ATP Binding Pocket Journal of Biological Chemistry. 273: 15605-15610. PMID 9624152 DOI: 10.1074/Jbc.273.25.15605 |
0.424 |
|
| 1998 |
Khokhlatchev AV, Canagarajah B, Wilsbacher J, Robinson M, Atkinson M, Goldsmith E, Cobb MH. Phosphorylation of the MAP kinase ERK2 promotes its homodimerization and nuclear translocation. Cell. 93: 605-15. PMID 9604935 DOI: 10.1016/S0092-8674(00)81189-7 |
0.488 |
|
| 1997 |
Canagarajah BJ, Khokhlatchev A, Cobb MH, Goldsmith EJ. Activation mechanism of the MAP kinase ERK2 by dual phosphorylation. Cell. 90: 859-69. PMID 9298898 DOI: 10.1016/S0092-8674(00)80351-7 |
0.536 |
|
| 1997 |
Wang Z, Harkins PC, Ulevitch RJ, Han J, Cobb MH, Goldsmith EJ. The structure of mitogen-activated protein kinase p38 at 2.1-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 94: 2327-32. PMID 9122194 DOI: 10.1073/Pnas.94.6.2327 |
0.535 |
|
| 1996 |
Wang Z, Mottonen J, Goldsmith EJ. Kinetically controlled folding of the serpin plasminogen activator inhibitor 1. Biochemistry. 35: 16443-16448. PMID 8987976 DOI: 10.1021/Bi961214P |
0.36 |
|
| 1996 |
Robinson MJ, Cheng M, Khokhlatchev A, Ebert D, Ahn N, Guan KL, Stein B, Goldsmith E, Cobb MH. Contributions of the mitogen-activated protein (MAP) kinase backbone and phosphorylation loop to MEK specificity. The Journal of Biological Chemistry. 271: 29734-9. PMID 8939908 DOI: 10.1074/Jbc.271.47.29734 |
0.496 |
|
| 1996 |
Cobb MH, Xu S, Cheng M, Ebert D, Robbins D, Goldsmith E, Robinson M. Structural analysis of the MAP kinase ERK2 and studies of MAP kinase regulatory pathways. Advances in Pharmacology (San Diego, Calif.). 36: 49-65. PMID 8783554 DOI: 10.1016/S1054-3589(08)60576-1 |
0.519 |
|
| 1996 |
Cheng M, Zhen E, Robinson MJ, Ebert D, Goldsmith E, Cobb MH. Characterization of a protein kinase that phosphorylates serine 189 of the mitogen-activated protein kinase homolog ERK3. The Journal of Biological Chemistry. 271: 12057-62. PMID 8662649 DOI: 10.1074/Jbc.271.20.12057 |
0.494 |
|
| 1996 |
Robinson MJ, Harkins PC, Zhang J, Baer R, Haycock JW, Cobb MH, Goldsmith EJ. Mutation of position 52 in ERK2 creates a nonproductive binding mode for adenosine 5'-triphosphate. Biochemistry. 35: 5641-6. PMID 8639522 DOI: 10.1021/Bi952723E |
0.457 |
|
| 1996 |
Goldsmith EJ. Allosteric enzymes as models for chemomechanical energy transducing assemblies. The Faseb Journal. 10: 702-708. PMID 8635687 DOI: 10.1096/Fasebj.10.7.8635687 |
0.334 |
|
| 1996 |
Wang Z, Han J, Goldsmith EJ. Crystallographic analysis of the MAP kinase P38 Acta Crystallographica Section A. 52: 190-191. DOI: 10.1107/S0108767396091702 |
0.396 |
|
| 1995 |
Cobb MH, Goldsmith EJ. How MAP kinases are regulated Journal of Biological Chemistry. 270: 14843-14846. PMID 7797459 DOI: 10.1074/Jbc.270.25.14843 |
0.404 |
|
| 1995 |
Grishin NV, Phillips MA, Goldsmith EJ. Modeling of the spatial structure of eukaryotic ornithine decarboxylases. Protein Science : a Publication of the Protein Society. 4: 1291-304. PMID 7670372 DOI: 10.1002/Pro.5560040705 |
0.392 |
|
| 1995 |
Tucker HM, Mottonen J, Goldsmith EJ, Gerard RD. Engineering of plasminogen activator inhibitor-1 to reduce the rate of latency transition. Nature Structural & Molecular Biology. 2: 442-445. PMID 7664104 DOI: 10.1038/Nsb0695-442 |
0.379 |
|
| 1995 |
Zhang J, Zhang F, Ebert D, Cobb MH, Goldsmith EJ. Activity of the MAP kinase ERK2 is controlled by a flexible surface loop Structure. 3: 299-307. PMID 7540485 DOI: 10.1016/S0969-2126(01)00160-5 |
0.548 |
|
| 1994 |
Zhang F, Strand A, Robbins D, Cobb MH, Goldsmith EJ. Atomic structure of the MAP kinase ERK2 at 2.3 A resolution. Nature. 367: 704-11. PMID 8107865 DOI: 10.1038/367704A0 |
0.552 |
|
| 1994 |
Goldsmith E, Mottonen J. Serpins: the uncut version Structure. 2: 241-244. PMID 8087550 DOI: 10.1016/S0969-2126(00)00025-3 |
0.382 |
|
| 1994 |
Tucker HM, Mottonen J, Goldsmith EJ, Gerard RD. The structural basis of latency in PAI-1 Fibrinolysis and Proteolysis. 8: 17. DOI: 10.1016/0268-9499(94)90332-8 |
0.303 |
|
| 1993 |
Zhang F, Robbins DJ, Cobb MH, Goldsmith EJ. Crystallization and preliminary X-ray studies of extracellular signal-regulated kinase-2/MAP kinase with an incorporated His-tag. Journal of Molecular Biology. 233: 550-2. PMID 8411162 DOI: 10.1006/Jmbi.1993.1532 |
0.469 |
|
| 1993 |
Madison EL, Kobe A, Gething MJ, Sambrook JF, Goldsmith EJ. Converting tissue plasminogen activator to a zymogen: a regulatory triad of Asp-His-Ser. Science (New York, N.Y.). 262: 419-21. PMID 8211162 DOI: 10.1126/Science.8211162 |
0.362 |
|
| 1992 |
Mottonen J, Strand A, Symersky J, Sweet RM, Danley DE, Geoghegan KF, Gerard RD, Goldsmith EJ. Structural basis of latency in plasminogen activator inhibitor-1. Nature. 355: 270-273. PMID 1731226 DOI: 10.1038/355270A0 |
0.451 |
|
| 1992 |
Boddupalli SS, Hasemann CA, Ravichandran KG, Lu JY, Goldsmith EJ, Deisenhofer J, Peterson JA. Crystallization and preliminary x-ray diffraction analysis of P450terp and the hemoprotein domain of P450BM-3, enzymes belonging to two distinct classes of the cytochrome P450 superfamily Proceedings of the National Academy of Sciences of the United States of America. 89: 5567-5571. PMID 1608967 DOI: 10.1073/Pnas.89.12.5567 |
0.324 |
|
| 1991 |
Goldsmith EJ, Sheng-Cheng C, Danley DE, Gerard RD, Geoghegan KF, Mottonen J, Strand A. Preliminary X-ray analysis of crystals of plasminogen activator inhibitor-1. Proteins. 9: 225-7. PMID 2006140 DOI: 10.1002/Prot.340090308 |
0.312 |
|
| 1991 |
Sprang SR, Withers SG, Goldsmith EJ, Fletterick RJ, Madsen NB. Structural basis for the activation of glycogen phosphorylase b by adenosine monophosphate. Science (New York, N.Y.). 254: 1367-71. PMID 1962195 DOI: 10.1126/Science.1962195 |
0.461 |
|
| 1990 |
Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF, Bassel-Duby RS. Amino acid residues that affect interaction of tissue-type plasminogen activator with plasminogen activator inhibitor 1. Proceedings of the National Academy of Sciences of the United States of America. 87: 3530-3. PMID 2110366 DOI: 10.1073/Pnas.87.9.3530 |
0.358 |
|
| 1989 |
Goldsmith EJ, Sprang SR, Hamlin R, Xuong NH, Fletterick RJ. Domain separation in the activation of glycogen phosphorylase a. Science (New York, N.Y.). 245: 528-32. PMID 2756432 DOI: 10.1126/Science.2756432 |
0.463 |
|
| 1989 |
Madison EL, Goldsmith EJ, Gerard RD, Gething MJ, Sambrook JF. Serpin-resistant mutants of human tissue-type plasminogen activator. Nature. 339: 721-4. PMID 2500599 DOI: 10.1038/339721A0 |
0.334 |
|
| 1988 |
Sprang SR, Acharya KR, Goldsmith EJ, Stuart DI, Varvill K, Fletterick RJ, Madsen NB, Johnson LN. Structural changes in glycogen phosphorylase induced by phosphorylation. Nature. 336: 215-21. PMID 3194008 DOI: 10.1038/336215A0 |
0.472 |
|
| 1987 |
Sprang S, Goldsmith E, Fletterick R. Structure of the nucleotide activation switch in glycogen phosphorylase a. Science (New York, N.Y.). 237: 1012-9. PMID 3616621 DOI: 10.1126/Science.3616621 |
0.394 |
|
| 1983 |
Goldsmith E, Fletterick RJ. Oligosaccharide conformation and protein saccharide interactions in solution Pure and Applied Chemistry. 55: 577-588. DOI: 10.1351/Pac198855040577 |
0.336 |
|
| 1982 |
Goldsmith E, Sprang S, Fletterick R. Structure of maltoheptaose by difference Fourier methods and a model for glycogen. Journal of Molecular Biology. 156: 411-27. PMID 7086906 DOI: 10.1016/0022-2836(82)90336-9 |
0.333 |
|
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