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Roopa Jones Ganji - Publications

Affiliations: 
Indian Institute of Chemical Technology, Hyderabad 
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11 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Reddi R, Ganji RJ, Marapaka AK, Bala SC, Yerra NV, Haque N, Addlagatta A. Puromycin, a selective inhibitor of PSA acts as a substrate for other M1 family aminopeptidases: Biochemical and structural basis. International Journal of Biological Macromolecules. PMID 33045297 DOI: 10.1016/j.ijbiomac.2020.10.035  0.769
2015 Aeluri R, Ganji RJ, Marapaka AK, Pillalamarri V, Alla M, Addlagatta A. Highly functionalized tetrahydropyridines are cytotoxic and selective inhibitors of human puromycin sensitive aminopeptidase. European Journal of Medicinal Chemistry. 106: 26-33. PMID 26513642 DOI: 10.1016/J.Ejmech.2015.10.026  0.78
2015 Arya T, Reddi R, Kishor C, Ganji RJ, Bhukya S, Gumpena R, McGowan S, Drag M, Addlagatta A. Identification of the molecular basis of inhibitor selectivity between the human and streptococcal type i methionine aminopeptidases Journal of Medicinal Chemistry. 58: 2350-2357. PMID 25699713 DOI: 10.1021/Jm501790E  0.726
2015 Ganji RJ, Reddi R, Gumpena R, Marapaka AK, Arya T, Sankoju P, Bhukya S, Addlagatta A. Structural basis for the inhibition of M1 family aminopeptidases by the natural product actinonin: Crystal structure in complex with E. coli aminopeptidase N. Protein Science : a Publication of the Protein Society. 24: 823-31. PMID 25644575 DOI: 10.1002/Pro.2653  0.733
2014 Manda BR, Alla M, Ganji RJ, Addlagatta A. Discovery of Tröger's base analogues as selective inhibitors against human breast cancer cell line: design, synthesis and cytotoxic evaluation. European Journal of Medicinal Chemistry. 86: 39-47. PMID 25140752 DOI: 10.1016/J.Ejmech.2014.08.044  0.656
2014 Reddi R, Arya T, Kishor C, Gumpena R, Ganji RJ, Bhukya S, Addlagatta A. Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents. The Febs Journal. 281: 4240-8. PMID 24841365 DOI: 10.1111/Febs.12847  0.709
2013 Rapolu S, Alla M, Ganji RJ, Saddanapu V, Kishor C, Bommena VR, Addlagatta A. Synthesis, cytotoxicity and hDHFR inhibition studies of 2H-pyrido[1,2-a]pyrimidin-2-ones Medchemcomm. 4: 817. DOI: 10.1039/C3Md00013C  0.725
2012 Gumpena R, Kishor C, Ganji RJ, Jain N, Addlagatta A. Glu121-Lys319 salt bridge between catalytic and N-terminal domains is pivotal for the activity and stability of Escherichia coli aminopeptidase N. Protein Science : a Publication of the Protein Society. 21: 727-36. PMID 22411732 DOI: 10.1002/Pro.2060  0.747
2012 Subba Reddy BV, Rajeswari N, Sarangapani M, Prashanthi Y, Ganji RJ, Addlagatta A. Iodine-catalyzed condensation of isatin with indoles: a facile synthesis of di(indolyl)indolin-2-ones and evaluation of their cytotoxicity. Bioorganic & Medicinal Chemistry Letters. 22: 2460-3. PMID 22386528 DOI: 10.1016/J.Bmcl.2012.02.011  0.629
2011 Gumpena R, Kishor C, Ganji RJ, Addlagatta A. Discovery of α,β- and α,γ-diamino acid scaffolds for the inhibition of M1 family aminopeptidases. Chemmedchem. 6: 1971-6. PMID 22025387 DOI: 10.1002/Cmdc.201100298  0.774
2010 Gumpena R, Kishor C, Ganji RJ, Addlagatta A. Discovery of alpha, beta- and alpha, gamma-Diamino Acid Scaffolds for the Inhibition of M1 Family Aminopeptidases Chemmedchem. 6: 1971-1976. DOI: 10.2210/Pdb3Ked/Pdb  0.719
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