Nicholas Proudfoot - Publications

Affiliations: 
Sir William Dunn School of Pathology University of Oxford, Oxford, United Kingdom 
Area:
mRNA processing, transcription termination

169 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Nojima T, Gomes T, Carmo-Fonseca M, Proudfoot NJ. Mammalian NET-seq analysis defines nascent RNA profiles and associated RNA processing genome-wide. Nature Protocols. 11: 413-28. PMID 26844429 DOI: 10.1038/nprot.2016.012  1
2016 West S, Proudfoot NJ. Correction to Transcriptional Termination Enhances Protein Expression in Human Cells [Molecular Cell, 33, 354-364, (2009)] Molecular Cell. 61: 486. DOI: 10.1016/j.molcel.2016.01.021  1
2015 Nojima T, Gomes T, Grosso AR, Kimura H, Dye MJ, Dhir S, Carmo-Fonseca M, Proudfoot NJ. Mammalian NET-Seq Reveals Genome-wide Nascent Transcription Coupled to RNA Processing. Cell. 161: 526-40. PMID 25910207 DOI: 10.1016/j.cell.2015.03.027  1
2015 Dhir A, Dhir S, Proudfoot NJ, Jopling CL. Microprocessor mediates transcriptional termination of long noncoding RNA transcripts hosting microRNAs. Nature Structural & Molecular Biology. 22: 319-27. PMID 25730776 DOI: 10.1038/nsmb.2982  1
2015 Hatchi E, Skourti-Stathaki K, Ventz S, Pinello L, Yen A, Kamieniarz-Gdula K, Dimitrov S, Pathania S, McKinney KM, Eaton ML, Kellis M, Hill SJ, Parmigiani G, Proudfoot NJ, Livingston DM. BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair. Molecular Cell. 57: 636-47. PMID 25699710 DOI: 10.1016/j.molcel.2015.01.011  1
2015 Grzechnik P, Gdula MR, Proudfoot NJ. Pcf11 orchestrates transcription termination pathways in yeast Genes and Development. 29: 849-861. DOI: 10.1101/gad.251470.114  1
2014 Skourti-Stathaki K, Proudfoot NJ. A double-edged sword: R loops as threats to genome integrity and powerful regulators of gene expression Genes and Development. 28: 1384-1396. PMID 24990962 DOI: 10.1101/gad.242990.114  1
2014 Grzechnik P, Tan-Wong SM, Proudfoot NJ. Terminate and make a loop: Regulation of transcriptional directionality Trends in Biochemical Sciences. 39: 319-327. PMID 24928762 DOI: 10.1016/j.tibs.2014.05.001  1
2014 White E, Schlackow M, Kamieniarz-Gdula K, Proudfoot NJ, Gullerova M. Human nuclear Dicer restricts the deleterious accumulation of endogenous double-stranded RNA. Nature Structural & Molecular Biology. 21: 552-9. PMID 24814348 DOI: 10.1038/nsmb.2827  1
2014 Skourti-Stathaki K, Kamieniarz-Gdula K, Proudfoot NJ. R-loops induce repressive chromatin marks over mammalian gene terminators Nature. 516: 436-439. DOI: 10.1038/nature13787  1
2013 Gromak N, Dienstbier M, Macias S, Plass M, Eyras E, Cáceres JF, Proudfoot NJ. Drosha regulates gene expression independently of RNA cleavage function. Cell Reports. 5: 1499-510. PMID 24360955 DOI: 10.1016/j.celrep.2013.11.032  1
2013 Skourti-Stathaki K, Proudfoot N. Histone 3 S10 Phosphorylation: "Caught in the R Loop!" Molecular Cell. 52: 470-472. PMID 24267448 DOI: 10.1016/j.molcel.2013.11.006  1
2013 Schlackow M, Marguerat S, Proudfoot NJ, Bähler J, Erban R, Gullerova M. Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe. Rna (New York, N.Y.). 19: 1617-31. PMID 24152550 DOI: 10.1261/rna.040675.113  1
2013 Tan-Wong SM, Proudfoot NJ. Rad51, friend or foe? Elife. 2013. PMID 23795299 DOI: 10.7554/eLife.00914  1
2013 Dhir A, Proudfoot NJ. Feed backwards model for microRNA processing and splicing in plants. Embo Reports. 14: 581-2. PMID 23764923 DOI: 10.1038/embor.2013.77  1
2013 Sun Q, Csorba T, Skourti-Stathaki K, Proudfoot NJ, Dean C. R-loop stabilization represses antisense transcription at the Arabidopsis FLC locus. Science (New York, N.Y.). 340: 619-21. PMID 23641115 DOI: 10.1126/science.1234848  1
2013 Nojima T, Dienstbier M, Murphy S, Proudfoot NJ, Dye MJ. Definition of RNA Polymerase II CoTC Terminator Elements in the Human Genome Cell Reports. 3: 1080-1092. PMID 23562152 DOI: 10.1016/j.celrep.2013.03.012  1
2013 White E, Kamieniarz-Gdula K, Dye MJ, Proudfoot NJ. AT-rich sequence elements promote nascent transcript cleavage leading to RNA polymerase II termination. Nucleic Acids Research. 41: 1797-806. PMID 23258704 DOI: 10.1093/nar/gks1335  1
2013 Mischo HE, Proudfoot NJ. Disengaging polymerase: Terminating RNA polymerase II transcription in budding yeast Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms. 1829: 174-185. PMID 23085255 DOI: 10.1016/j.bbagrm.2012.10.003  1
2012 Gullerova M, Proudfoot NJ. Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells Nature Structural and Molecular Biology. 19: 1193-1201. PMID 23022730 DOI: 10.1038/nsmb.2392  1
2012 Tan-Wong SM, Zaugg JB, Camblong J, Xu Z, Zhang DW, Mischo HE, Ansari AZ, Luscombe NM, Steinmetz LM, Proudfoot NJ. Gene loops enhance transcriptional directionality. Science (New York, N.Y.). 338: 671-5. PMID 23019609 DOI: 10.1126/science.1224350  1
2012 Henriques T, Ji Z, Tan-Wong SM, Carmo AM, Tian B, Proudfoot NJ, Moreira A. Transcription termination between polo and snap, two closely spaced tandem genes of D. melanogaster. Transcription. 3: 198-212. PMID 22992452 DOI: 10.4161/trns.21967  1
2012 Avendaño-Vázquez SE, Dhir A, Bembich S, Buratti E, Proudfoot N, Baralle FE. Autoregulation of TDP-43 mRNA levels involves interplay between transcription, splicing, and alternative polyA site selection. Genes & Development. 26: 1679-84. PMID 22855830 DOI: 10.1101/gad.194829.112  1
2011 Proudfoot NJ. Ending the message: Poly(A) signals then and now Genes and Development. 25: 1770-1782. PMID 21896654 DOI: 10.1101/gad.17268411  1
2011 Skourti-Stathaki K, Proudfoot NJ, Gromak N. Human Senataxin Resolves RNA/DNA Hybrids Formed at Transcriptional Pause Sites to Promote Xrn2-Dependent Termination Molecular Cell. 42: 794-805. PMID 21700224 DOI: 10.1016/j.molcel.2011.04.026  1
2011 Pinto PA, Henriques T, Freitas MO, Martins T, Domingues RG, Wyrzykowska PS, Coelho PA, Carmo AM, Sunkel CE, Proudfoot NJ, Moreira A. RNA polymerase II kinetics in polo polyadenylation signal selection. The Embo Journal. 30: 2431-44. PMID 21602789 DOI: 10.1038/emboj.2011.156  1
2011 Gullerova M, Moazed D, Proudfoot NJ. Autoregulation of convergent RNAi genes in fission yeast. Genes & Development. 25: 556-68. PMID 21357674 DOI: 10.1101/gad.618611  1
2011 Mischo HE, Gómez-González B, Grzechnik P, Rondón AG, Wei W, Steinmetz L, Aguilera A, Proudfoot NJ. Yeast Sen1 helicase protects the genome from transcription-associated instability Molecular Cell. 41: 21-32. PMID 21211720 DOI: 10.1016/j.molcel.2010.12.007  1
2011 Braglia P, Kawauchi J, Proudfoot NJ. Co-transcriptional RNA cleavage provides a failsafe termination mechanism for yeast RNA polymerase i Nucleic Acids Research. 39: 1439-1448. PMID 20972219 DOI: 10.1093/nar/gkq894  1
2010 Gullerova M, Proudfoot NJ. Transcriptional interference and gene orientation in yeast: Noncoding RNA connections Cold Spring Harbor Symposia On Quantitative Biology. 75: 299-311. PMID 21467144 DOI: 10.1101/sqb.2010.75.048  1
2010 Braglia P, Heindl K, Schleiffer A, Martinez J, Proudfoot NJ. Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase i Embo Reports. 11: 758-764. PMID 20814424 DOI: 10.1038/embor.2010.130  1
2010 Kaufmann I, White E, Azad A, Marguerat S, Bähler J, Proudfoot NJ. Transcriptional activation of the general amino acid permease gene per1 by the histone deacetylase Clr6 Is regulated by Oca2 kinase. Molecular and Cellular Biology. 30: 3396-410. PMID 20404084 DOI: 10.1128/MCB.00971-09  1
2010 Gullerova M, Proudfoot NJ. Silencing in trans: Position matters in fission yeast Embo Reports. 11: 145-146. PMID 20154645 DOI: 10.1038/embor.2010.24  1
2009 Tan-Wong SM, Wijayatilake HD, Proudfoot NJ. Gene loops function to maintain transcriptional memory through interaction with the nuclear pore complex Genes and Development. 23: 2610-2624. PMID 19933151 DOI: 10.1101/gad.1823209  1
2009 Rondón AG, Mischo HE, Kawauchi J, Proudfoot NJ. Fail-Safe Transcriptional Termination for Protein-Coding Genes in S. cerevisiae Molecular Cell. 36: 88-98. PMID 19818712 DOI: 10.1016/j.molcel.2009.07.028  1
2009 Ballarino M, Pagano F, Girardi E, Morlando M, Cacchiarelli D, Marchioni M, Proudfoot NJ, Bozzoni I. Coupled RNA processing and transcription of intergenic primary microRNAs Molecular and Cellular Biology. 29: 5632-5638. PMID 19667074 DOI: 10.1128/MCB.00664-09  1
2009 Webby CJ, Wolf A, Gromak N, Dreger M, Kramer H, Kessler B, Nielsen ML, Schmitz C, Butler DS, Yates JR, Delahunty CM, Hahn P, Lengeling A, Mann M, Proudfoot NJ, et al. Jmjd6 catalyses lysyl-hydroxylation of U2AF65, a protein associated with RNA splicing. Science (New York, N.Y.). 325: 90-3. PMID 19574390 DOI: 10.1126/science.1175865  1
2009 West S, Proudfoot NJ. Transcriptional Termination Enhances Protein Expression in Human Cells Molecular Cell. 33: 354-364. PMID 19217409 DOI: 10.1016/j.molcel.2009.01.008  1
2008 Rondon AG, Proudfoot NJ. Nuclear Roadblocks for mRNA Export Cell. 135: 207-208. PMID 18957194 DOI: 10.1016/j.cell.2008.09.053  1
2008 Perkins KJ, Proudfoot NJ. An Ungracious Host for an Unwelcome Guest Cell Host and Microbe. 4: 89-91. PMID 18692766 DOI: 10.1016/j.chom.2008.07.010  1
2008 Rondon AG, Mischo HE, Proudfoot NJ. Terminating transcription in yeast: Whether to be a 'nerd' or a 'rat' Nature Structural and Molecular Biology. 15: 775-776. PMID 18679429 DOI: 10.1038/nsmb0808-775  1
2008 Kawauchi J, Mischo H, Braglia P, Rondon A, Proudfoot NJ. Budding yeast RNA polymerases I and II employ parallel mechanisms of transcriptional termination Genes and Development. 22: 1082-1092. PMID 18413718 DOI: 10.1101/gad.463408  1
2008 Tan-Wong SM, French JD, Proudfoot NJ, Brown MA. Dynamic interactions between the promoter and terminator regions of the mammalian BRCA1 gene. Proceedings of the National Academy of Sciences of the United States of America. 105: 5160-5. PMID 18375767 DOI: 10.1073/pnas.0801048105  1
2008 Gullerova M, Proudfoot NJ. Cohesin Complex Promotes Transcriptional Termination between Convergent Genes in S. pombe Cell. 132: 983-995. PMID 18358811 DOI: 10.1016/j.cell.2008.02.040  1
2008 West S, Proudfoot NJ, Dye MJ. Molecular Dissection of Mammalian RNA Polymerase II Transcriptional Termination Molecular Cell. 29: 600-610. PMID 18342606 DOI: 10.1016/j.molcel.2007.12.019  1
2008 Perkins KJ, Lusic M, Mitar I, Giacca M, Proudfoot NJ. Transcription-Dependent Gene Looping of the HIV-1 Provirus Is Dictated by Recognition of Pre-mRNA Processing Signals Molecular Cell. 29: 56-68. PMID 18206969 DOI: 10.1016/j.molcel.2007.11.030  1
2008 West S, Proudfoot NJ. Human Pcf11 enhances degradation of RNA polymerase II-associated nascent RNA and transcriptional termination Nucleic Acids Research. 36: 905-914. PMID 18086705 DOI: 10.1093/nar/gkm1112  1
2008 Gromak N, Talotti G, Proudfoot NJ, Pagani F. Modulating alternative splicing by cotranscriptional cleavage of nascent intronic RNA Rna. 14: 359-366. PMID 18065715 DOI: 10.1261/rna.615508  1
2008 Morlando M, Ballarino M, Gromak N, Pagano F, Bozzoni I, Proudfoot NJ. Primary microRNA transcripts are processed co-transcriptionally Chemtracts. 21: 381-383. DOI: 10.1038/nsmb.1475  1
2007 Proudfoot N, Gullerova M. Gene Silencing CUTs Both Ways Cell. 131: 649-651. PMID 18022358 DOI: 10.1016/j.cell.2007.11.003  1
2007 Jones HS, Kawauchi J, Braglia P, Alen CM, Kent NA, Proudfoot NJ. RNA polymerase I in yeast transcribes dynamic nucleosomal rDNA Nature Structural and Molecular Biology. 14: 123-130. PMID 17259992 DOI: 10.1038/nsmb1199  1
2006 Dye MJ, Gromak N, Haussecker D, West S, Proudfoot NJ. Turnover and function of noncoding RNA polymerase II transcripts Cold Spring Harbor Symposia On Quantitative Biology. 71: 275-284. PMID 17381307 DOI: 10.1101/sqb.2006.71.040  1
2006 Binnie A, Castelo-Branco P, Monks J, Proudfoot NJ. Homologous gene sequences mediate transcription-domain formation Journal of Cell Science. 119: 3876-3887. PMID 16940354 DOI: 10.1242/jcs.03050  1
2006 Gromak N, West S, Proudfoot NJ. Pause sites promote transcriptional termination of mammalian RNA polymerase II Molecular and Cellular Biology. 26: 3986-3996. PMID 16648491 DOI: 10.1128/MCB.26.10.3986-3996.2006  1
2006 West S, Zaret K, Proudfoot NJ. Transcriptional termination sequences in the mouse serum albumin gene Rna. 12: 655-665. PMID 16581808 DOI: 10.1261/rna.2232406  1
2006 Dye MJ, Gromak N, Proudfoot NJ. Exon tethering in transcription by RNA polymerase II Molecular Cell. 21: 849-859. PMID 16543153 DOI: 10.1016/j.molcel.2006.01.032  1
2006 West S, Gromak N, Norbury CJ, Proudfoot NJ. Adenylation and exosome-mediated degradation of cotranscriptionally cleaved pre-messenger RNA in human cells. Molecular Cell. 21: 437-43. PMID 16455498 DOI: 10.1016/j.molcel.2005.12.008  1
2005 Haussecker D, Proudfoot NJ. Dicer-dependent turnover of intergenic transcripts from the human β-globin gene cluster Molecular and Cellular Biology. 25: 9724-9733. PMID 16227618 DOI: 10.1128/MCB.25.21.9724-9733.2005  1
2005 Plant KE, Dye MJ, Lafaille C, Proudfoot NJ. Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Gγ-globin gene Molecular and Cellular Biology. 25: 3276-3285. PMID 15798211 DOI: 10.1128/MCB.25.8.3276-3285.2005  1
2005 Ares M, Proudfoot NJ. The Spanish connection: Transcription and mRNA processing get even closer Cell. 120: 163-166. PMID 15680322 DOI: 10.1016/j.cell.2005.01.002  1
2004 Teixeira A, Tahiri-Alaoui A, West S, Thomas B, Ramadass A, Martianov I, Dye M, James W, Proudfoot NJ, Akoulitchev A. Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination. Nature. 432: 526-30. PMID 15565159 DOI: 10.1038/nature03032  1
2004 West S, Gromak N, Proudfoot NJ. Human 5′ → 3′ exonuclease Xm2 promotes transcription termination at co-transcriptional cleavage sites Nature. 432: 522-525. PMID 15565158 DOI: 10.1038/nature03035  1
2004 O'Sullivan JM, Tan-Wong SM, Morillon A, Lee B, Coles J, Mellor J, Proudfoot NJ. Gene loops juxtapose promoters and terminators in yeast. Nature Genetics. 36: 1014-8. PMID 15314641 DOI: 10.1038/ng1411  1
2004 Proudfoot N. New perspectives on connecting messenger RNA 3′ end formation to transcription Current Opinion in Cell Biology. 16: 272-278. PMID 15145351 DOI: 10.1016/j.ceb.2004.03.007  1
2004 Castelo-Branco P, Furger A, Wollerton M, Smith C, Moreira A, Proudfoot N. Polypyrimidine tract binding protein modulates efficiency of polyadenylation Molecular and Cellular Biology. 24: 4174-4183. PMID 15121839 DOI: 10.1128/MCB.24.10.4174-4183.2004  1
2004 Prescott EM, Osheim YN, Jones HS, Alen CM, Roan JG, Reeder RH, Beyer AL, Proudfoot NJ. Transcriptional termination by RNA polymerase I requires the small subunit Rpa12p. Proceedings of the National Academy of Sciences of the United States of America. 101: 6068-73. PMID 15073335 DOI: 10.1073/pnas.0401393101  1
2003 Morillon A, Karabetsou N, O'Sullivan J, Kent N, Proudfoot N, Mellor J. Isw1 Chromatin Remodeling ATPase Coordinates Transcription Elongation and Termination by RNA Polymerase II Cell. 115: 425-435. PMID 14622597 DOI: 10.1016/S0092-8674(03)00880-8  1
2003 Proudfoot NJ. Dawdling polymerases allow introns time to splice Nature Structural Biology. 10: 876-878. PMID 14583735 DOI: 10.1038/nsb1103-876  1
2003 Morillon A, O'Sullivan J, Azad A, Proudfoot N, Mellor J. Regulation of elongating RNA polymerase II by forkhead transcription factors in yeast Science. 300: 492-495. PMID 12702877 DOI: 10.1126/science.1081379  1
2002 Alén C, Kent NA, Jones HS, O'Sullivan J, Aranda A, Proudfoot NJ. A role for chromatin remodeling in transcriptional termination by RNA polymerase II Molecular Cell. 10: 1441-1452. PMID 12504018 DOI: 10.1016/S1097-2765(02)00778-5  1
2002 Proudfoot N, O'Sullivan J. Polyadenylation: A tail of two complexes Current Biology. 12: R855-R857. PMID 12498707 DOI: 10.1016/S0960-9822(02)01353-2  1
2002 Routledge SJE, Proudfoot NJ. Definition of transcriptional promoters in the human β globin locus control region Journal of Molecular Biology. 323: 601-611. PMID 12419253 DOI: 10.1016/S0022-2836(02)01011-2  1
2002 Furger A, O'Sullivan JM, Binnie A, Lee BA, Proudfoot NJ. Promoter proximal splice sites enhance transcription Genes and Development. 16: 2792-2799. PMID 12414732 DOI: 10.1101/gad.983602  1
2002 Kwek KY, Murphy S, Furger A, Thomas B, O'Gorman W, Kimura H, Proudfoot NJ, Akoulitchev A. U1 snRNA associates with TFIIH and regulates transcriptional initiation. Nature Structural Biology. 9: 800-5. PMID 12389039 DOI: 10.1038/nsb862  1
2002 Prescott EM, Proudfoot NJ. Transcriptional collision between convergent genes in budding yeast. Proceedings of the National Academy of Sciences of the United States of America. 99: 8796-801. PMID 12077310 DOI: 10.1073/pnas.132270899  1
2002 Proudfoot NJ, Furger A, Dye MJ. Integrating mRNA processing with transcription. Cell. 108: 501-12. PMID 11909521 DOI: 10.1016/S0092-8674(02)00617-7  1
2001 Furger A, Monks J, Proudfoot NJ. The retroviruses human immunodeficiency virus type 1 and Moloney murine leukemia virus adopt radically different strategies to regulate promoter-proximal polyadenylation. Journal of Virology. 75: 11735-46. PMID 11689654 DOI: 10.1128/JVI.75.23.11735-11746.2001  1
2001 Proudfoot NJ. Genetic dangers in poly(A) signals. Embo Reports. 2: 891-2. PMID 11600452 DOI: 10.1093/embo-reports/kve207  1
2001 Plant KE, Routledge SJ, Proudfoot NJ. Intergenic transcription in the human beta-globin gene cluster. Molecular and Cellular Biology. 21: 6507-14. PMID 11533239 DOI: 10.1128/MCB.21.19.6507-6514.2001  1
2001 Aranda A, Proudfoot N. Transcriptional termination factors for RNA polymerase II in yeast. Molecular Cell. 7: 1003-11. PMID 11389847 DOI: 10.1016/S1097-2765(01)00235-0  1
2001 Dye MJ, Proudfoot NJ. Multiple transcript cleavage precedes polymerase release in termination by RNA polymerase II. Cell. 105: 669-81. PMID 11389836 DOI: 10.1016/S0092-8674(01)00372-5  1
2001 Barillà D, Lee BA, Proudfoot NJ. Cleavage/polyadenylation factor IA associates with the carboxyl-terminal domain of RNA polymerase II in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 98: 445-50. PMID 11149954 DOI: 10.1073/pnas.021545298  1
2000 Yonaha M, Proudfoot NJ. Transcriptional termination and coupled polyadenylation in vitro. The Embo Journal. 19: 3770-7. PMID 10899130 DOI: 10.1093/emboj/19.14.3770  1
2000 Greger IH, Aranda A, Proudfoot N. Balancing transcriptional interference and initiation on the GAL7 promoter of Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 97: 8415-20. PMID 10890898 DOI: 10.1073/pnas.140217697  1
2000 Proudfoot N. Connecting transcription to messenger RNA processing. Trends in Biochemical Sciences. 25: 290-3. PMID 10838569 DOI: 10.1016/S0968-0004(00)01591-7  1
2000 Brackenridge S, Proudfoot NJ. Recruitment of a basal polyadenylation factor by the upstream sequence element of the human lamin B2 polyadenylation signal. Molecular and Cellular Biology. 20: 2660-9. PMID 10733568 DOI: 10.1128/MCB.20.8.2660-2669.2000  1
2000 Ashe MP, Furger A, Proudfoot NJ. Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation. Rna (New York, N.Y.). 6: 170-7. PMID 10688356 DOI: 10.1017/S1355838200991957  1
1999 Yonaha M, Proudfoot NJ. Specific transcriptional pausing activates polyadenylation in a coupled in vitro system. Molecular Cell. 3: 593-600. PMID 10360175 DOI: 10.1016/S1097-2765(00)80352-4  1
1999 Cuello P, Boyd DC, Dye MJ, Proudfoot NJ, Murphy S. Transcription of the human U2 snRNA genes continues beyond the 3' box in vivo. The Embo Journal. 18: 2867-77. PMID 10329632 DOI: 10.1093/emboj/18.10.2867  1
1999 Osheim YN, Proudfoot NJ, Beyer AL. EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage. Molecular Cell. 3: 379-87. PMID 10198640 DOI: 10.1016/S1097-2765(00)80465-7  1
1999 Dye MJ, Proudfoot NJ. Terminal exon definition occurs cotranscriptionally and promotes termination of RNA polymerase II. Molecular Cell. 3: 371-8. PMID 10198639 DOI: 10.1016/S1097-2765(00)80464-5  1
1999 Aranda A, Proudfoot NJ. Definition of transcriptional pause elements in fission yeast. Molecular and Cellular Biology. 19: 1251-61. PMID 9891059  1
1998 Roberts GC, Gooding C, Mak HY, Proudfoot NJ, Smith CW. Co-transcriptional commitment to alternative splice site selection. Nucleic Acids Research. 26: 5568-72. PMID 9837984  1
1998 Moreira A, Takagaki Y, Brackenridge S, Wollerton M, Manley JL, Proudfoot NJ. The upstream sequence element of the C2 complement poly(A) signal activates mRNA 3' end formation by two distinct mechanisms. Genes & Development. 12: 2522-34. PMID 9716405  1
1998 Greger IH, Proudfoot NJ. Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae Embo Journal. 17: 4771-4779. PMID 9707436 DOI: 10.1093/emboj/17.16.4771  1
1998 Hansen K, Birse CE, Proudfoot NJ. Nascent transcription from the nmt1 and nmt2 genes of Schizosaccharomyces pombe overlaps neighbouring genes Embo Journal. 17: 3066-3077. PMID 9606189 DOI: 10.1093/emboj/17.11.3066  1
1998 Birse CE, Minvielle-Sebastia L, Lee BA, Keller W, Proudfoot NJ. Coupling termination of transcription to messenger RNA maturation in yeast Science. 280: 298-301. PMID 9535662 DOI: 10.1126/science.280.5361.298  1
1998 Greger IH, Demarchi F, Giacca M, Proudfoot NJ. Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter Nucleic Acids Research. 26: 1294-1300. PMID 9469840 DOI: 10.1093/nar/26.5.1294  1
1997 Proudfoot NJ. 20 years of making messenger RNA Trends in Genetics. 13: 430. PMID 9385837 DOI: 10.1016/S0168-9525(97)90004-4  1
1997 Ashe HL, Monks J, Wijgerde M, Fraser P, Proudfoot NJ. Intergenic transcription and transinduction of the human β-globin locus Genes and Development. 11: 2494-2509. PMID 9334315  1
1997 Ashe MP, Pearson LH, Proudfoot NJ. The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site. The Embo Journal. 16: 5752-63. PMID 9312033 DOI: 10.1093/emboj/16.18.5752  1
1997 Birse CE, Lee BA, Hansen K, Proudfoot NJ. Transcriptional termination signals for RNA polymerase II in fission yeast Embo Journal. 16: 3633-3643. PMID 9218804 DOI: 10.1093/emboj/16.12.3633  1
1997 Brackenridge S, Ashe HL, Giacca M, Proudfoot NJ. Transcription and polyadenylation in a short human intergenic region Nucleic Acids Research. 25: 2326-2335. PMID 9171082 DOI: 10.1093/nar/25.12.2326  1
1996 Proudfoot N. Ending the message is not so simple Cell. 87: 779-781. PMID 8945502 DOI: 10.1016/S0092-8674(00)81982-0  1
1996 Pondel MD, Sharpe JA, Clark S, Pearson L, Wood WG, Proudfoot NJ. Proximal promoter elements of the human zeta-globin gene confer embryonic-specific expression on a linked reporter gene in transgenic mice. Nucleic Acids Research. 24: 4158-64. PMID 8932366 DOI: 10.1093/nar/24.21.4158  1
1996 Williams RD, Lee BA, Jackson SP, Proudfoot NJ. Activation domains of transcription factors mediate replication dependent transcription from a minimal HIV-1 promoter Nucleic Acids Research. 24: 549-557. PMID 8604293 DOI: 10.1093/nar/24.4.549  1
1995 Santis AG, López-Cabrera M, Sánchez-Madrid F, Proudfoot N. Expression of the early lymphocyte activation antigen CD69, a C-type lectin, is regulated by mRNA degradation associated with AU-rich sequence motifs European Journal of Immunology. 25: 2142-2146. PMID 7664776 DOI: 10.1002/eji.1830250804  1
1995 Moreira A, Wollerton M, Monks J, Proudfoot NJ. Upstream sequence elements enhance poly(A) site efficiency of the C2 complement gene and are phylogenetically conserved Embo Journal. 14: 3809-3819. PMID 7641699  1
1995 Pondel MD, Murphy S, Pearson L, Craddock C, Proudfoot NJ. Sp1 functions in a chromatin-dependent manner to augment human alpha-globin promoter activity. Proceedings of the National Academy of Sciences of the United States of America. 92: 7237-41. PMID 7638173 DOI: 10.1073/pnas.92.16.7237  1
1995 Ashe MP, Griffin P, James W, Proudfoot NJ. Poly(A) site selection in the HIV-1 provirus: inhibition of promoter-proximal polyadenylation by the downstream major splice donor site. Genes & Development. 9: 3008-25. PMID 7498796  1
1994 Humphrey T, Birse CE, Proudfoot NJ. RNA 3′ end signals of the S.pombe ura4 gene comprise a site determining and efficiency element Embo Journal. 13: 2441-2451. PMID 8194534  1
1994 Ashfield R, Patel AJ, Bossone SA, Brown H, Campbell RD, Marcu KB, Proudfoot NJ. MAZ-dependent termination between closely spaced human complement genes. The Embo Journal. 13: 5656-67. PMID 7988563  1
1994 Proudfoot NJ. Post-Transcriptional Regulation: Chasing your own poly(A) tail Current Biology. 4: 359-361. PMID 7922347 DOI: 10.1016/S0960-9822(00)00080-4  1
1994 Manley JL, Proudfoot NJ. RNA 3' ends: formation and function--meeting review. Genes & Development. 8: 259-64. PMID 7906236  1
1993 Eggermont J, Proudfoot NJ. Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters Embo Journal. 12: 2539-2548. PMID 8508777  1
1993 Watt P, Lamb P, Proudfoot NJ. Distinct negative regulation of the human embryonic globin genes zeta and epsilon Gene Expression. 3: 61-75. PMID 8508028  1
1993 Weichs an der Glon C, Ashe M, Eggermont J, Proudfoot NJ. Tat-dependent occlusion of the HIV poly(A) site. The Embo Journal. 12: 2119-28. PMID 8491200  1
1992 Pondel MD, George M, Proudfoot NJ. The LCR-like α-globin positive regulatory element functions as an enhancer in transiently transfected cells during erythroid differentiation Nucleic Acids Research. 20: 237-243. PMID 1741249  1
1992 Proudfoot NJ, Lee BA, Monks J. Multiple SP1 binding sites confer enhancer-independent, replication-activated transcription of HIV-1 and globin gene promoters The New Biologist. 4: 369-381. PMID 1622932  1
1992 Pondel MD, Proudfoot NJ, Whitelaw C, Whitelaw E. The developmental regulation of the human ζ-globin gene in transgenic mice employing β-galactosidase as a reporter gene Nucleic Acids Research. 20: 5655-5660. PMID 1454528  1
1992 Owczarek CM, Enriquez-Harris P, Proudfoot NJ. The primary transcription unit of the human α2 globin gene defined by quantitative RT/PCR Nucleic Acids Research. 20: 851-858. PMID 1371868  1
1991 Enriquez-Harris P, Levitt N, Briggs D, Proudfoot NJ. A pause site for RNA polymerase II is associated with termination of transcription Embo Journal. 10: 1833-1842. PMID 2050120  1
1991 An Der Glon CW, Monks J, Proudfoot NJ. Occlusion of the HIV poly(A) site Genes and Development. 5: 244-253. PMID 1995416  1
1991 Proudfoot NJ. Meeting review. High altitude termination New Biologist. 3: 851-854. PMID 1931828  1
1991 Humphrey T, Sadhale P, Platt T, Proudfoot N. Homologous mRNA 3′ end formation in fission and budding yeast Embo Journal. 10: 3503-3511. PMID 1915305  1
1990 Watt P, Lamb P, Squire L, Proudfoot N. A factor binding GATAAG confers tissue specificity on the promoter of the human ζ-globin gene Nucleic Acids Research. 18: 1339-1350. PMID 2326182  1
1989 Leung SO, Whitelaw E, Proudfoot NJ. Transcriptional and translational analysis of the human θ globin gene Nucleic Acids Research. 17: 8283-8300. PMID 2813063 DOI: 10.1093/nar/17.20.8283  1
1989 Briggs D, Jackson D, Whitelaw E, Proudfoot NJ. Direct demonstration of termination signals for RNA polymerase II from the sea urchin H2A histone gene Nucleic Acids Research. 17: 8061-8071. PMID 2813057 DOI: 10.1093/nar/17.20.8061  1
1989 Proudfoot NJ. How RNA polymerase II terminates transcription in higher eukaryotes Trends in Biochemical Sciences. 14: 105-110. PMID 2658217 DOI: 10.1016/0968-0004(89)90132-1  1
1989 Manley JL, Proudfoot NJ, Platt T. RNA 3'-end formation. Genes & Development. 3: 2218-22. PMID 2628168  1
1989 Whitelaw E, Lamb P, Hogben P, Proudfoot NJ. The globin switch at the level of mRNA in the developing mouse Progress in Clinical and Biological Research. 316: 323-333. PMID 2594813  1
1989 Lamb P, Watt P, Proudfoot NJ. Negative regulation of the human embryonic globin genes zeta and epsilon Progress in Clinical and Biological Research. 316: 269-277. PMID 2594809  1
1989 Levitt N, Briggs D, Gil A, Proudfoot NJ. Definition of an efficient synthetic poly(A) site Genes & Development. 3: 1019-1025. PMID 2570734  1
1989 Whitelaw E, Hogben P, Hanscombe O, Proudfoot NJ. Transcriptional promiscuity of the human α-globin gene Molecular and Cellular Biology. 9: 241-251. PMID 2538719  1
1988 Humphrey T, Proudfoot NJ. A beginning to the biochemistry of polyadenylation Trends in Genetics. 4: 243-245. PMID 2853468 DOI: 10.1016/0168-9525(88)90028-5  1
1987 Leung SO, Proudfoot NJ, Whitelaw E. The gene for θ-globin is transcribed in human fetal erythroid tissues Nature. 329: 551-554. PMID 3657976  1
1987 Gil A, Proudfoot NJ. Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit β-globin mRNA 3′ end formation Cell. 49: 399-406. PMID 3568131 DOI: 10.1016/0092-8674(87)90292-3  1
1987 Norman C, Raymond V, Proudfoot NJ. Transcriptional regulation of human zeta and psi zeta globin genes Progress in Clinical and Biological Research. 251: 235-252. PMID 3432269  1
1986 Proudfoot NJ. Transcriptional interference and termination between duplicated α-globin gene constructs suggests a novel mechanism for gene regulation Nature. 322: 562-565. PMID 3736674 DOI: 10.1038/322562a0  1
1986 Proudfoot N. Molecular biology: Globin gene monkey business Nature. 321: 730-731. PMID 3713860 DOI: 10.1038/321730a0  1
1986 Whitelaw E, Coates A, Proudfoot NJ. Globin gene transcripts can utilize histone gene 3′ end processing signals Nucleic Acids Research. 14: 7059-7070. PMID 3463933 DOI: 10.1093/nar/14.17.7059  1
1986 Johnson MR, Norman C, Reeve MA, Scully J, Proudfoot NJ. Tripartite sequences within and 3' to the sea urchin H2A histone gene display properties associated with a transcriptional termination process. Molecular and Cellular Biology. 6: 4008-18. PMID 3025624  1
1986 Whitelaw E, Proudfoot N. Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin gene Embo Journal. 5: 2915-2922. PMID 3024968  1
1985 Proudfoot NJ, Gil A, Whitelaw E. Studies on messenger RNA 3' end formation in globin genes: a transcriptional interference model for globin gene switching Progress in Clinical and Biological Research. 191: 49-65. PMID 2413484  1
1984 Proudfoot NJ, Rutherford TR, Partington GA. Transcriptional analysis of human zeta globin genes Embo Journal. 3: 1533-1540. PMID 6745241  1
1984 Proudfoot N. Gene expression: The end of the message and beyond Nature. 307: 412-413. PMID 6694735 DOI: 10.1038/307412a0  1
1984 Gil A, Proudfoot NJ. A sequence downstream of AAUAAA is required for rabbit β-globin mRNA 3′-end formation Nature. 312: 473-474. PMID 6095108 DOI: 10.1038/312473a0  1
1983 Higgs DR, Goodbourn SEY, Lamb J, Clegg JB, Weatherall DJ, Proudfoot NJ. α-Thalassaemia caused by a polyadenylation signal mutation Nature. 306: 398-400. PMID 6646217 DOI: 10.1038/306398a0  1
1983 Whitelaw E, Proudfoot NJ. Transcriptional activity of the human psendogene φα globin compared with α globin, its functional gene counterpart Nucleic Acids Research. 11: 7717-7733. PMID 6316269 DOI: 10.1093/nar/11.22.7717  1
1982 Treisman R, Proudfoot NJ, Shander M, Maniatis T. A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing. Cell. 29: 903-11. PMID 7151176 DOI: 10.1016/0092-8674(82)90452-4  1
1982 Proudfoot N. The end of the message Nature. 298: 516-517. PMID 7099250 DOI: 10.1038/298516a0  1
1982 Proudfoot NJ, Gil A, Maniatis T. The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene. Cell. 31: 553-63. PMID 6297773 DOI: 10.1016/0092-8674(82)90311-7  1
1980 Proudfoot N. Pseudogenes Nature. 286: 840-841. PMID 7412866 DOI: 10.1038/286840a0  1
1980 Proudfoot NJ, Maniatis T. The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication. Cell. 21: 537-44. PMID 7407925  1
1980 Efstratiadis A, Posakony JW, Maniatis T, Lawn RM, O'Connell C, Spritz RA, DeRiel JK, Forget BG, Weissman SM, Slightom JL, Blechl AE, Smithies O, Baralle FE, Shoulders CC, Proudfoot NJ. The structure and evolution of the human beta-globin gene family. Cell. 21: 653-68. PMID 6985477 DOI: 10.1016/0092-8674(80)90429-8  1
1980 Baralle FE, Proudfoot NJ, Clegg JB. The structural analysis of the human epsilon-globin gene and its product Annals of the New York Academy of Sciences. 344: 76-82. PMID 6930885  1
1980 Baralle FE, Shoulders CC, Proudfoot NJ. The primary structure of the human ε-globin gene Cell. 21: 621-626. PMID 6254663  1
1980 Baralle FE, Shoulders CC, Goodbourn S, Jeffreys A, Proudfoot NJ. The 5′ flanking region of human ε-globin gene Nucleic Acids Research. 8: 4393-4404. PMID 6253916 DOI: 10.1093/nar/8.19.4393  1
1980 Proudfoot NJ, Shander MH, Manley JL, Gefter ML, Maniatis T. Structure and in vitro transcription of human globin genes. Science (New York, N.Y.). 209: 1329-36. PMID 6158093  1
1979 Proudfoot NJ, Baralle FE. Molecular cloning of human ε-globin gene Proceedings of the National Academy of Sciences of the United States of America. 76: 5435-5439. PMID 160554  1
1978 Old JM, Proudfoot NJ, Wood WG, Longley JI, Clegg JB, Weatherall DJ. Characterization of β-globin mRNA in the β0 thalassemias Cell. 14: 289-298. PMID 667941 DOI: 10.1016/0092-8674(78)90115-0  1
1977 Proudfoot NJ, Gillam S, Smith M, Longley JI. Nucleotide sequence of the 3′ terminal third of rabbit α-globin messenger RNA: Comparison with human α-globin messenger RNA Cell. 11: 807-818. PMID 70277 DOI: 10.1016/0092-8674(77)90293-8  1
1977 Proudfoot NJ. Complete 3′ noncoding region sequences of rabbit and human β-globin messenger RNAs Cell. 10: 559-570. PMID 67897 DOI: 10.1016/0092-8674(77)90089-7  1
1977 Proudfoot NJ. The sequence is not enough Nature. 265: 499-500. DOI: 10.1038/265499a0  1
1976 Proudfoot NJ, Cheng CC, Brownlee GG. Sequence analysis of eukaryotic mRNA. Progress in Nucleic Acid Research and Molecular Biology. 19: 123-34. PMID 828277  1
1976 Proudfoot NJ, Brownlee GG. 3' non-coding region sequences in eukaryotic messenger RNA. Nature. 263: 211-4. PMID 822353 DOI: 10.1038/263211a0  1
1976 Proudfoot NJ, Brownlee GG. Nucleotide sequences of globin messenger RNA. British Medical Bulletin. 32: 251-6. PMID 788834  1
1974 Milstein C, Brownlee GG, Cartwright EM, Jarvis JM, Proudfoot NJ. Sequence analysis of immunoglobulin light chain messenger RNA. Nature. 252: 354-9. PMID 4473725 DOI: 10.1038/252354a0  1
1974 Proudfoot NJ, Brownlee GG. Sequence at the 3' end of globin mRNA shows homology with immunoglobulin light chain mRNA. Nature. 252: 359-62. PMID 4139664  1
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