James R Hagman - Publications

Affiliations: 
National Jewish Health 
Area:
B cells, T cells, gene expression, epigenetics

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Hagman JR, Arends T, Laborda C, Knapp JR, Harmacek L, O'Connor BP. Chromodomain helicase DNA-binding 4 (CHD4) regulates early B cell identity and V(D)J recombination. Immunological Reviews. PMID 34927255 DOI: 10.1111/imr.13054  0.482
2021 Somasundaram R, Jensen CT, Tingvall-Gustafsson J, Åhsberg J, Okuyama K, Prasad M, Hagman J, Wang X, Soneji S, Strid T, Ungerbäck J, Sigvardsson M. EBF1 and PAX5 control pro-B cell expansion via opposing regulation of the Myc gene. Blood. PMID 33619557 DOI: 10.1182/blood.2020009564  0.501
2021 Li Y, Gao J, Kamran M, Harmacek L, Danhorn T, Leach SM, O'Connor BP, Hagman JR, Huang H. GATA2 regulates mast cell identity and responsiveness to antigenic stimulation by promoting chromatin remodeling at super-enhancers. Nature Communications. 12: 494. PMID 33479210 DOI: 10.1038/s41467-020-20766-0  0.411
2019 Hernandez G, Mills TS, Rabe JL, Chavez JS, Kuldanek S, Kirkpatrick G, Noetzli L, Jubair WK, Zanche M, Meyers JR, Stevens BM, Fleenor CJ, Adane B, Dinarello CA, Ashton J, ... ... Hagman JR, et al. Pro-inflammatory cytokine blockade attenuates myeloid expansion in a murine model of rheumatoid arthritis. Haematologica. PMID 31101752 DOI: 10.3324/Haematol.2018.197210  0.336
2019 Arends T, Dege C, Bortnick A, Danhorn T, Knapp JR, Jia H, Harmacek L, Fleenor CJ, Straign D, Walton K, Leach SM, Feeney AJ, Murre C, O'Connor BP, Hagman JR. CHD4 is essential for transcriptional repression and lineage progression in B lymphopoiesis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31085655 DOI: 10.1073/Pnas.1821301116  0.584
2019 Chavez J, Rabe JL, Higa K, Loeffler D, Nouraiz A, Mills T, Idler BM, Stevens BM, Fleenor C, Nerlov C, Nakajima H, Hagman J, Schroeder T, Kim HM, Jordan CT, et al. PU.1 Enforces Hematopoietic Stem Cell Quiescence during Chronic Inflammation Blood. 134: 822-822. DOI: 10.1182/Blood-2019-129300  0.399
2018 Fleenor CJ, Arends T, Lei H, Åhsberg J, Okuyama K, Kuruvilla J, Cristobal S, Rabe JL, Pandey A, Danhorn T, Straign D, Espinosa JM, Warming S, Pietras EM, Sigvardsson M, ... Hagman JR, et al. Zinc Finger Protein 521 regulates early hematopoiesis through cell extrinsic mechanisms in the bone marrow microenvironment. Molecular and Cellular Biology. PMID 29915154 DOI: 10.1128/Mcb.00603-17  0.5
2018 Liu H, Wang C, Lee S, Ning F, Wang Y, Zhang Q, Chen Z, Zang J, Nix J, Dai S, Marrack P, Hagman J, Kappler J, Zhang G. Specific Recognition of Arginine Methylated Histone Tails by JMJD5 and JMJD7. Scientific Reports. 8: 3275. PMID 29459673 DOI: 10.1038/S41598-018-21432-8  0.341
2018 Mills T, Hernandez G, Rabe JL, Kuldanek S, Chavez J, Kirkpatrick G, Noetzli L, Jubair W, Zanche M, Myers JR, Stevens BM, Fleenor C, Adane B, Ashton JM, Jordan CT, ... Hagman J, et al. Rheumatoid Arthritis Causes Hematopoietic Stem Cell Reprogramming to Maintain Functionality Blood. 132: 2573-2573. DOI: 10.1182/Blood-2018-99-120272  0.389
2017 Li Y, Liu B, Harmacek L, Long Z, Liang J, Lukin K, Leach SM, O'Connor B, Gerber AN, Hagman J, Roers A, Finkelman FD, Huang H. The transcription factors GATA2 and MITF regulate Hdc gene expression in mast cells and are required for IgE/mast cell-mediated anaphylaxis. The Journal of Allergy and Clinical Immunology. PMID 29277702 DOI: 10.1016/J.Jaci.2017.10.043  0.455
2017 Hagman J. Critical Functions of IRF4 in B and T Lymphocytes. Journal of Immunology (Baltimore, Md. : 1950). 199: 3715-3716. PMID 29158346 DOI: 10.4049/Jimmunol.1701385  0.477
2017 Liu H, Wang C, Lee S, Deng Y, Wither M, Oh S, Ning F, Dege C, Zhang Q, Liu X, Johnson AM, Zang J, Chen Z, Janknecht R, Hansen K, ... ... Hagman J, et al. Clipping of arginine-methylated histone tails by JMJD5 and JMJD7. Proceedings of the National Academy of Sciences of the United States of America. PMID 28847961 DOI: 10.1073/Pnas.1706831114  0.364
2016 Sleven H, Welsh SJ, Yu J, Churchill ME, Wright CF, Henderson A, Horvath R, Rankin J, Vogt J, Magee A, McConnell V, Green A, King MD, Cox H, Armstrong L, ... ... Hagman J, et al. De Novo Mutations in EBF3 Cause a Neurodevelopmental Syndrome. American Journal of Human Genetics. PMID 28017370 DOI: 10.1016/J.Ajhg.2016.11.020  0.354
2016 Hagman J. Editorial overview: Lymphocyte development and activation: Lymphoid cell differentiation: choosing paths to traverse the immune landscape. Current Opinion in Immunology. PMID 26923180 DOI: 10.1016/J.Coi.2016.02.005  0.347
2016 Hayashi M, Jin Y, Yorgov D, Santorico SA, Hagman J, Ferrara TM, Jones KL, Cavalli G, Dinarello CA, Spritz RA. Autoimmune vitiligo is associated with gain-of-function by a transcriptional regulator that elevates expression of HLA-A*02:01 in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26787886 DOI: 10.1073/Pnas.1525001113  0.371
2016 Jones CL, Kirkpatrick G, Fleenor C, Seth W, Noetzli LJ, Fosmire S, Baturin D, Liang X, Hernandez G, Pietras EM, Jordan CT, Rowley JW, Di Paola J, Hagman JR, Porter CC. ETV6 Regulates Pax5 Expression in Early B Cell Development Blood. 128: 2655-2655. DOI: 10.1182/Blood.V128.22.2655.2655  0.515
2016 Jones CL, Fleenor CJ, Welsh S, Noetzli L, Fosmire S, Baturin D, Paola JD, Hagman JR, Porter CC. Abstract 2000: ETV6 represses Pax5 in early B-cell development Cancer Research. 76: 2000-2000. DOI: 10.1158/1538-7445.Am2016-2000  0.548
2016 Hayashi M, Jin Y, Yorgov D, Santorico SA, Hagman J, Spritz RA. Autoimmune vitiligo is associated with a transcriptional regulator that affects expression of HLA-A*02: 01 in vivo Journal of Dermatological Science. 84. DOI: 10.1016/J.Jdermsci.2016.08.420  0.399
2015 Prasad MA, Ungerbäck J, Åhsberg J, Somasundaram R, Strid T, Larsson M, Månsson R, De Paepe A, Lilljebjörn H, Fioretos T, Hagman J, Sigvardsson M. Ebf1 heterozygosity results in increased DNA damage in pro-B cells and their synergistic transformation by Pax5 haploinsufficiency. Blood. 125: 4052-9. PMID 25838350 DOI: 10.1182/Blood-2014-12-617282  0.473
2014 Dege C, Hagman J. Mi-2/NuRD chromatin remodeling complexes regulate B and T-lymphocyte development and function. Immunological Reviews. 261: 126-40. PMID 25123281 DOI: 10.1111/Imr.12209  0.541
2013 Hagman J, Lukin K. Plasma cells for hire: prior experience required. Immunity. 39: 89-91. PMID 23890066 DOI: 10.1016/J.Immuni.2013.07.009  0.363
2013 Wang M, Ramirez J, Han J, Jia Y, Domenico J, Seibold MA, Hagman JR, Gelfand EW. The steroidogenic enzyme Cyp11a1 is essential for development of peanut-induced intestinal anaphylaxis. The Journal of Allergy and Clinical Immunology. 132: 1174-1183.e8. PMID 23870673 DOI: 10.1016/J.Jaci.2013.05.027  0.319
2013 Collins B, Clambey ET, Scott-Browne J, White J, Marrack P, Hagman J, Kappler JW. Ikaros promotes rearrangement of TCR α genes in an Ikaros null thymoma cell line. European Journal of Immunology. 43: 521-32. PMID 23172374 DOI: 10.1002/Eji.201242757  0.384
2013 Dege C, Hagman J. Activation of Aicda gene transcription by Pax5 in plasmacytoma cells. Immunologic Research. 55: 155-61. PMID 22956488 DOI: 10.1007/S12026-012-8357-8  0.512
2012 Ramírez J, Dege C, Kutateladze TG, Hagman J. MBD2 and multiple domains of CHD4 are required for transcriptional repression by Mi-2/NuRD complexes. Molecular and Cellular Biology. 32: 5078-88. PMID 23071088 DOI: 10.1128/Mcb.00819-12  0.468
2012 Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE. Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly. Developmental Cell. 22: 459-67. PMID 22340503 DOI: 10.1016/J.Devcel.2011.12.010  0.391
2012 Musselman CA, Ramírez J, Sims JK, Mansfield RE, Oliver SS, Denu JM, Mackay JP, Wade PA, Hagman J, Kutateladze TG. Bivalent recognition of nucleosomes by the tandem PHD fingers of the CHD4 ATPase is required for CHD4-mediated repression. Proceedings of the National Academy of Sciences of the United States of America. 109: 787-92. PMID 22215588 DOI: 10.1073/Pnas.1113655109  0.382
2012 Hagman J, Ramírez J, Lukin K. B lymphocyte lineage specification, commitment and epigenetic control of transcription by early B cell factor 1. Current Topics in Microbiology and Immunology. 356: 17-38. PMID 21735360 DOI: 10.1007/82_2011_139  0.567
2012 Musselman CA, Ramirez J, Sims JK, Mansfield RE, Oliver SS, Denu JM, Mackay JP, Wade PA, Hagman J, Kutateladze TG. Bivalent Recognition of a Single Nucleosome by the Tandem PHD Fingers of CHD4 is Required for CHD4-Mediated Repression Biophysical Journal. 102: 480a. DOI: 10.1016/J.Bpj.2011.11.2630  0.386
2011 Lukin K, Fields S, Guerrettaz L, Straign D, Rodriguez V, Zandi S, Månsson R, Cambier JC, Sigvardsson M, Hagman J. A dose-dependent role for EBF1 in repressing non-B-cell-specific genes. European Journal of Immunology. 41: 1787-93. PMID 21469119 DOI: 10.1002/Eji.201041137  0.547
2010 Lin YC, Jhunjhunwala S, Benner C, Heinz S, Welinder E, Mansson R, Sigvardsson M, Hagman J, Espinoza CA, Dutkowski J, Ideker T, Glass CK, Murre C. A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate. Nature Immunology. 11: 635-43. PMID 20543837 DOI: 10.1038/Ni.1891  0.52
2010 Lukin K, Fields S, Lopez D, Cherrier M, Ternyak K, Ramírez J, Feeney AJ, Hagman J. Compound haploinsufficiencies of Ebf1 and Runx1 genes impede B cell lineage progression. Proceedings of the National Academy of Sciences of the United States of America. 107: 7869-74. PMID 20385820 DOI: 10.1073/Pnas.1003525107  0.527
2010 Ramírez J, Lukin K, Hagman J. From hematopoietic progenitors to B cells: mechanisms of lineage restriction and commitment. Current Opinion in Immunology. 22: 177-84. PMID 20207529 DOI: 10.1016/J.Coi.2010.02.003  0.566
2009 Ramírez J, Hagman J. The Mi-2/NuRD complex: a critical epigenetic regulator of hematopoietic development, differentiation and cancer. Epigenetics. 4: 532-6. PMID 19923891 DOI: 10.4161/Epi.4.8.10108  0.447
2009 Hagman J. Conveying the message: identification of Ig-alpha and Ig-beta as components of the B cell receptor complex. Journal of Immunology (Baltimore, Md. : 1950). 183: 1503-4. PMID 19620315 DOI: 10.4049/Jimmunol.0990055  0.406
2009 Fitzsimmons D, Lukin K, Lutz R, Garvie CW, Wolberger C, Hagman J. Highly cooperative recruitment of Ets-1 and release of autoinhibition by Pax5. Journal of Molecular Biology. 392: 452-64. PMID 19616560 DOI: 10.1016/J.Jmb.2009.07.028  0.378
2009 Gao H, Lukin K, Ramírez J, Fields S, Lopez D, Hagman J. Opposing effects of SWI/SNF and Mi-2/NuRD chromatin remodeling complexes on epigenetic reprogramming by EBF and Pax5. Proceedings of the National Academy of Sciences of the United States of America. 106: 11258-63. PMID 19549820 DOI: 10.1073/Pnas.0809485106  0.557
2009 Thal MA, Carvalho TL, He T, Kim HG, Gao H, Hagman J, Klug CA. Ebf1-mediated down-regulation of Id2 and Id3 is essential for specification of the B cell lineage. Proceedings of the National Academy of Sciences of the United States of America. 106: 552-7. PMID 19122139 DOI: 10.1073/Pnas.0802550106  0.506
2008 Lukin K, Fields S, Hartley J, Hagman J. Early B cell factor: Regulator of B lineage specification and commitment. Seminars in Immunology. 20: 221-7. PMID 18722139 DOI: 10.1016/J.Smim.2008.07.004  0.539
2008 Fields S, Ternyak K, Gao H, Ostraat R, Akerlund J, Hagman J. The 'zinc knuckle' motif of Early B cell Factor is required for transcriptional activation of B cell-specific genes. Molecular Immunology. 45: 3786-96. PMID 18606452 DOI: 10.1016/J.Molimm.2008.05.018  0.559
2008 Fields SA, Lukin KL, Månsson R, Cherrier M, Straign D, Speck NA, Grosschedl R, Feeney A, Sigvardsson M, Hagman J. EBF and Runx1 are required for B cell specific transcription and lineage identity The Faseb Journal. 22: 350-350. DOI: 10.1096/Fasebj.22.2_Supplement.350  0.552
2008 Lukin K, Straign D, Behrens T, Busslinger M, Hagman J. Loss of pax5 heterozygosity in mice promotes B cell‐specific lymphoproliferative disease The Faseb Journal. 22: 348-348. DOI: 10.1096/Fasebj.22.2_Supplement.348  0.362
2007 Hagman J, Lukin K. "Hands-on" regulation of B cell development by the transcription factor Pax5. Immunity. 27: 8-10. PMID 17663980 DOI: 10.1016/J.Immuni.2007.07.001  0.544
2007 Wojcik H, Griffiths E, Staggs S, Hagman J, Winandy S. Expression of a non-DNA-binding Ikaros isoform exclusively in B cells leads to autoimmunity but not leukemogenesis. European Journal of Immunology. 37: 1022-32. PMID 17357110 DOI: 10.1002/Eji.200637026  0.535
2007 Kappes D, Hagman J. Lymphocyte development. Regulation of B and T lymphoid cell development Current Opinion in Immunology. 19: 113-115. DOI: 10.1016/J.Coi.2007.02.015  0.437
2006 Zhang Z, Espinoza CR, Yu Z, Stephan R, He T, Williams GS, Burrows PD, Hagman J, Feeney AJ, Cooper MD. Transcription factor Pax5 (BSAP) transactivates the RAG-mediated V(H)-to-DJ(H) rearrangement of immunoglobulin genes. Nature Immunology. 7: 616-24. PMID 16680144 DOI: 10.1038/Ni1339  0.383
2006 Chen Z, Zang J, Whetstine J, Hong X, Davrazou F, Kutateladze TG, Simpson M, Mao Q, Pan CH, Dai S, Hagman J, Hansen K, Shi Y, Zhang G. Structural insights into histone demethylation by JMJD2 family members. Cell. 125: 691-702. PMID 16677698 DOI: 10.1016/J.Cell.2006.04.024  0.38
2006 Hagman J, Lukin K. Transcription factors drive B cell development. Current Opinion in Immunology. 18: 127-34. PMID 16464566 DOI: 10.1016/J.Coi.2006.01.007  0.547
2005 Hagman J, Lukin K. Early B-cell factor 'pioneers' the way for B-cell development. Trends in Immunology. 26: 455-61. PMID 16027038 DOI: 10.1016/J.It.2005.07.001  0.576
2004 Steinke JW, Hodsdon W, Parenti S, Ostraat R, Lutz R, Borish L, Hagman J. Identification of an Sp factor-dependent promoter in GCET, a gene expressed at high levels in germinal center B cells. Molecular Immunology. 41: 1145-53. PMID 15482850 DOI: 10.1016/J.Molimm.2004.06.031  0.542
2004 Maier H, Ostraat R, Gao H, Fields S, Shinton SA, Medina KL, Ikawa T, Murre C, Singh H, Hardy RR, Hagman J. Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription. Nature Immunology. 5: 1069-77. PMID 15361869 DOI: 10.1038/Ni1119  0.572
2004 Steinke JW, Barekzi E, Hagman J, Borish L. Functional analysis of -571 IL-10 promoter polymorphism reveals a repressor element controlled by sp1. Journal of Immunology (Baltimore, Md. : 1950). 173: 3215-22. PMID 15322183 DOI: 10.4049/Jimmunol.173.5.3215  0.351
2003 Maier H, Ostraat R, Parenti S, Fitzsimmons D, Abraham LJ, Garvie CW, Hagman J. Requirements for selective recruitment of Ets proteins and activation of mb-1/Ig-alpha gene transcription by Pax-5 (BSAP). Nucleic Acids Research. 31: 5483-9. PMID 14500810 DOI: 10.1093/Nar/Gkg785  0.49
2003 Maier H, Colbert J, Fitzsimmons D, Clark DR, Hagman J. Activation of the early B-cell-specific mb-1 (Ig-alpha) gene by Pax-5 is dependent on an unmethylated Ets binding site. Molecular and Cellular Biology. 23: 1946-60. PMID 12612069 DOI: 10.1128/Mcb.23.6.1946-1960.2003  0.509
2003 Steinke JW, Owens AM, Hagman J, Borish L. Sp1/Sp3 and Pax-5 transcription factors mediate activation of the germinal center B-cell-specific M17 promoter The Journal of Allergy and Clinical Immunology. 111. DOI: 10.1016/S0091-6749(03)81011-4  0.448
2002 Maier H, Hagman J. Roles of EBF and Pax-5 in B lineage commitment and development. Seminars in Immunology. 14: 415-22. PMID 12457614 DOI: 10.1016/S1044532302000763  0.547
2002 Sigvardsson M, Clark DR, Fitzsimmons D, Doyle M, Akerblad P, Breslin T, Bilke S, Li R, Yeamans C, Zhang G, Hagman J. Early B-cell factor, E2A, and Pax-5 cooperate to activate the early B cell-specific mb-1 promoter. Molecular and Cellular Biology. 22: 8539-51. PMID 12446773 DOI: 10.1128/Mcb.22.24.8539-8551.2002  0.571
2001 Garvie CW, Hagman J, Wolberger C. Structural studies of Ets-1/Pax5 complex formation on DNA. Molecular Cell. 8: 1267-76. PMID 11779502 DOI: 10.1016/S1097-2765(01)00410-5  0.414
2001 Fitzsimmons D, Lutz R, Wheat W, Chamberlin HM, Hagman J. Highly conserved amino acids in Pax and Ets proteins are required for DNA binding and ternary complex assembly Nucleic Acids Research. 29: 4154-4165. PMID 11600704 DOI: 10.1093/Nar/29.20.4154  0.384
2001 Makar KW, Ulgiati D, Hagman J, Holers VM. A site in the complement receptor 2 (CR2/CD21) silencer is necessary for lineage specific transcriptional regulation International Immunology. 13: 657-664. PMID 11312253 DOI: 10.1093/Intimm/13.5.657  0.446
1999 Hagman J, Wheat W, Fitzsimmons D, Hodsdon W, Negri J, Dizon F. Pax-5/BSAP: Regulator of specific gene expression and differentiation in B lymphocytes Current Topics in Microbiology and Immunology. 245: 169-194. PMID 10533313 DOI: 10.1007/978-3-642-57066-7_5  0.492
1999 Wheat W, Fitzsimmons D, Lennox H, Krautkramer SR, Gentile LN, McIntosh LP, Hagman J. The highly conserved β-hairpin of the paired DNA-binding domain is required for assembly of Pax-Ets ternary complexes Molecular and Cellular Biology. 19: 2231-2241. PMID 10022910 DOI: 10.1128/Mcb.19.3.2231  0.419
1998 Wasylyk B, Hagman J, Gutierrez-Hartmann A. Ets transcription factors: Nuclear effectors of the Ras-MAP-kinase signaling pathway Trends in Biochemical Sciences. 23: 213-216. PMID 9644975 DOI: 10.1016/S0968-0004(98)01211-0  0.393
1996 Fitzsimmons D, Hodsdon W, Wheat W, Maira SM, Wasylyk B, Hagman J. Pax-5 (BSAP) recruits ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter Genes and Development. 10: 2198-2211. PMID 8804314 DOI: 10.1101/Gad.10.17.2198  0.528
1996 Fitzsimmons D, Hagman J. Regulation of gene expression at early stages of B-cell and T-cell differentiation Current Opinion in Immunology. 8: 166-174. PMID 8725939 DOI: 10.1016/S0952-7915(96)80054-9  0.518
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