Erden Banoglu - Publications

Affiliations: 
Department of Pharmaceutical Chemistry Gazi University 

61 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gedik ME, Saatci O, Oberholtzer N, Uner M, Akbulut O, Cetin M, Aras M, Ibis K, Caliskan B, Banoglu E, Wiemann S, Uner A, Aksoy S, Mehrotra S, Sahin O. Reviving immunogenic cell death upon targeting TACC3 enhances T-DM1 response in HER2-positive breast cancer. Biorxiv : the Preprint Server For Biology. PMID 37745348 DOI: 10.1101/2023.09.12.557273  0.768
2023 Olğaç A, Çapan İ, Dahlke P, Jordan PM, Werz O, Banoglu E. Substituted 1,2,4-Triazoles as Novel and Selective Inhibitors of Leukotriene Biosynthesis Targeting 5-Lipoxygenase-Activating Protein. Acs Omega. 8: 31293-31304. PMID 37663492 DOI: 10.1021/acsomega.3c03682  0.828
2023 Saatci O, Akbulut O, Cetin M, Sikirzhytski V, Uner M, Lengerli D, O'Quinn EC, Romeo MJ, Caliskan B, Banoglu E, Aksoy S, Uner A, Sahin O. Targeting TACC3 represents a novel vulnerability in highly aggressive breast cancers with centrosome amplification. Cell Death and Differentiation. PMID 36864125 DOI: 10.1038/s41418-023-01140-1  0.716
2023 Gur Maz T, Koc B, Jordan PM, İbiş K, Çalışkan B, Werz O, Banoglu E. Benzoxazolone-5-Urea Derivatives as Human Soluble Epoxide Hydrolase (sEH) Inhibitors. Acs Omega. 8: 2445-2454. PMID 36687110 DOI: 10.1021/acsomega.2c06936  0.852
2022 Turanlı S, Ergül AG, Jordan PM, Olğaç A, Çalışkan B, Werz O, Banoglu E. Quinazoline-4(3)-one-7-carboxamide Derivatives as Human Soluble Epoxide Hydrolase Inhibitors with Developable 5-Lipoxygenase Activating Protein Inhibition. Acs Omega. 7: 36354-36365. PMID 36278102 DOI: 10.1021/acsomega.2c04039  0.846
2022 Turanlı S, Nalbat E, Lengerli D, İbiş K, Güntekin Ergün S, Akhan Güzelcan E, Muyan M, Cetin-Atalay R, Çalışkan B, Banoglu E. Vicinal Diaryl-Substituted Isoxazole and Pyrazole Derivatives with Growth Inhibitory and Antitumor Activity. Acs Omega. 7: 36206-36226. PMID 36278052 DOI: 10.1021/acsomega.2c03405  0.83
2022 Lengerli D, Ibis K, Nural Y, Banoglu E. The 1,2,3-triazole "all-in-one" ring system in drug discovery: a good bioisostere, a good pharmacophore, a good linker, and a versatile synthetic tool. Expert Opinion On Drug Discovery. PMID 36164263 DOI: 10.1080/17460441.2022.2129613  0.767
2022 Gur Maz T, Turanlı S, Caliskan HB, Çalışkan B, Banoglu E. Development and molecular modeling studies of new thiadiazole piperazine urea derivatives as potential fatty acid amide hydrolase inhibitors. Archiv Der Pharmazie. e2200082. PMID 35500130 DOI: 10.1002/ardp.202200082  0.807
2022 Çapan İ, Jordan PM, Olğaç A, Çalışkan B, Kretzer C, Werz O, Banoglu E. Discovery and optimization of piperazine urea derivatives as soluble epoxide hydrolase (sEH) inhibitors. Chemmedchem. PMID 35466565 DOI: 10.1002/cmdc.202200137  0.827
2022 Banoglu E, Ercanlı T, Gür Maz T, Vullo D, Bonardi A, Gratteri P, Supuran CT. A Series of Thiadiazolyl-Benzenesulfonamides Incorporating an Aromatic Tail as Isoform-Selective, Potent Carbonic Anhydrase II/XII Inhibitors. Chemmedchem. e202200056. PMID 35266325 DOI: 10.1002/cmdc.202200056  0.324
2022 Ergül AG, Maz TG, Kretzer C, Olğaç A, Jordan PM, Çalışkan B, Werz O, Banoglu E. Novel potent benzimidazole-based microsomal prostaglandin E synthase-1 (mPGES-1) inhibitors derived from BRP-201 that also inhibit leukotriene C synthase. European Journal of Medicinal Chemistry. 231: 114167. PMID 35152061 DOI: 10.1016/j.ejmech.2022.114167  0.845
2021 İbiş K, Nalbat E, Çalışkan B, Kahraman DC, Cetin-Atalay R, Banoglu E. Synthesis and biological evaluation of novel isoxazole-piperazine hybrids as potential anti-cancer agents with inhibitory effect on liver cancer stem cells. European Journal of Medicinal Chemistry. 221: 113489. PMID 33951549 DOI: 10.1016/j.ejmech.2021.113489  0.809
2021 Gürses T, Olğaç A, Garscha U, Gür Maz T, Bal NB, Uludağ O, Çalışkan B, Schubert US, Werz O, Banoglu E. Simple heteroaryl modifications in the 4,5-diarylisoxazol-3-carboxylic acid scaffold favorably modulates the activity as dual mPGES-1/5-LO inhibitors with in vivo efficacy. Bioorganic Chemistry. 112: 104861. PMID 33826984 DOI: 10.1016/j.bioorg.2021.104861  0.837
2020 Shkodra-Pula B, Kretzer C, Jordan PM, Klemm P, Koeberle A, Pretzel D, Banoglu E, Lorkowski S, Wallert M, Höppener S, Stumpf S, Vollrath A, Schubert S, Werz O, Schubert US. Encapsulation of the dual FLAP/mPEGS-1 inhibitor BRP-187 into acetalated dextran and PLGA nanoparticles improves its cellular bioactivity. Journal of Nanobiotechnology. 18: 73. PMID 32408877 DOI: 10.1186/S12951-020-00620-7  0.478
2020 Akbulut O, Lengerli D, Saatci O, Duman E, Seker UOS, Isik A, Akyol A, Caliskan B, Banoglu E, Şahin Ö. A Highly Potent TACC3 Inhibitor as a Novel Anti-cancer Drug Candidate. Molecular Cancer Therapeutics. PMID 32217742 DOI: 10.1158/1535-7163.Mct-19-0957  0.756
2020 Olgac A, Carotti A, Kretzer C, Zergiebel S, Seeling A, Garscha U, Werz O, Macchiarulo A, Banoglu E. Discovery of novel 5-lipoxygenase-activating protein (FLAP) inhibitors by exploiting a multistep virtual screening protocol. Journal of Chemical Information and Modeling. PMID 32045233 DOI: 10.1021/Acs.Jcim.9B00941  0.843
2020 Özdemir A, Turanli S, Çalişkan B, Arka M, Banoglu E. Evaluation of Cytotoxic Activity of New Benzimidazole-Piperazine Hybrids Against Human MCF-7 and A549 Cancer Cells Pharmaceutical Chemistry Journal. 53: 1036-1046. DOI: 10.1007/S11094-020-02119-9  0.778
2019 Uslu AG, Gür Maz T, Nocentini A, Banoglu E, Supuran CT, Çalışkan B. Benzimidazole derivatives as potent and isoform selective tumor-associated carbonic anhydrase IX/XII inhibitors. Bioorganic Chemistry. 95: 103544. PMID 31915112 DOI: 10.1016/J.Bioorg.2019.103544  0.767
2019 Boccellino M, Donniacuo M, Bruno F, Rinaldi B, Quagliuolo L, Ambruosi M, Pace S, De Rosa M, Olgaç A, Banoglu E, Alessio N, Massa A, Kahn H, Werz O, Fiorentino A, et al. Protective effect of piceatannol and bioactive stilbene derivatives against hypoxia-induced toxicity in H9c2 cardiomyocytes and structural elucidation as 5-LOX inhibitors. European Journal of Medicinal Chemistry. 180: 637-647. PMID 31351395 DOI: 10.1016/J.Ejmech.2019.07.033  0.831
2019 Mostarda S, Gür Maz T, Piccinno A, Cerra B, Banoglu E. Optimisation by Design of Experiment of Benzimidazol-2-One Synthesis under Flow Conditions. Molecules (Basel, Switzerland). 24. PMID 31277341 DOI: 10.3390/Molecules24132447  0.302
2019 Shekfeh S, Çalışkan B, Fischer K, Yalçın T, Garscha U, Werz O, Banoglu E. A Multi-step Virtual Screening Protocol for the Identification of Novel Non-acidic Microsomal Prostaglandin E Synthase-1 (mPGES-1) Inhibitors. Chemmedchem. 14: 273-281. PMID 30537167 DOI: 10.1002/Cmdc.201800701  0.806
2019 Akbulut O, Lengerli D, Saatci O, Duman E, Seker U, Caliskan B, Banoglu E, Sahin O. Abstract 3871: A novel TACC3 inhibitor as an anti-cancer agent in breast cancer Cancer Research. 79: 3871-3871. DOI: 10.1158/1538-7445.Am2019-3871  0.775
2018 Çalışkan B, Sinoplu E, İbiş K, Akhan Güzelcan E, Çetin Atalay R, Banoglu E. Synthesis and cellular bioactivities of novel isoxazole derivatives incorporating an arylpiperazine moiety as anticancer agents. Journal of Enzyme Inhibition and Medicinal Chemistry. 33: 1352-1361. PMID 30251900 DOI: 10.1080/14756366.2018.1504041  0.801
2018 Bruno F, Errico S, Pace S, Nawrozkij MB, Mkrtchyan AS, Guida F, Maisto R, Olgaç A, D'Amico M, Maione S, De Rosa M, Banoglu E, Werz O, Fiorentino A, Filosa R. Structural insight into the optimization of ethyl 5-hydroxybenzo[g]indol-3-carboxylates and their bioisosteric analogues as 5-LO/m-PGES-1 dual inhibitors able to suppress inflammation. European Journal of Medicinal Chemistry. 155: 946-960. PMID 30015253 DOI: 10.1016/J.Ejmech.2018.05.041  0.832
2018 Gür ZT, Çalışkan B, Garscha U, Olgaç A, Schubert US, Gerstmeier J, Werz O, Banoglu E. Identification of multi-target inhibitors of leukotriene and prostaglandin Ebiosynthesis by structural tuning of the FLAP inhibitor BRP-7. European Journal of Medicinal Chemistry. 150: 876-899. PMID 29597170 DOI: 10.1016/J.Ejmech.2018.03.045  0.847
2018 Gür ZT, Şenol FS, Shekfeh S, Orhan İE, Banoğlu E, Çalişkan B. Novel Piperazine Amides of Cinnamic Acid Derivatives as Tyrosinase Inhibitors Letters in Drug Design & Discovery. 16: 36-44. DOI: 10.2174/1570180815666180420105652  0.822
2017 Olğaç A, Orhan IE, Banoglu E. The potential role of in silico approaches to identify novel bioactive molecules from natural resources. Future Medicinal Chemistry. 9: 1665-1686. PMID 28841048 DOI: 10.4155/Fmc-2017-0124  0.766
2017 Gür ZT, Çalışkan B, Banoglu E. Drug discovery approaches targeting 5-lipoxygenase-activating protein (FLAP) for inhibition of cellular leukotriene biosynthesis. European Journal of Medicinal Chemistry. PMID 28784429 DOI: 10.1016/J.Ejmech.2017.07.019  0.787
2017 Orhan IE, Senol FS, Shekfeh S, Skalicka-Wozniak K, Banoglu E. Pteryxin - A promising butyrylcholinesterase-inhibiting coumarin derivative from Mutellina purpurea. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. PMID 28286309 DOI: 10.1016/J.Fct.2017.03.016  0.432
2016 Garscha U, Voelker S, Pace S, Gerstmeier J, Emini B, Liening S, Rossi A, Weinigel C, Rummler S, Schubert US, E Scriba GK, Çelikoğlu E, Çalışkan B, Banoglu E, Sautebin L, et al. BRP-187: a potent inhibitor of leukotriene biosynthesis that acts through impeding the dynamic 5-lipoxygenase / 5-lipoxygenase-activating protein (FLAP) complex assembly. Biochemical Pharmacology. PMID 27592027 DOI: 10.1016/J.Bcp.2016.08.023  0.798
2016 Levent S, Gerstmeier J, Olgaç A, Nikels F, Garscha U, Carotti A, Macchiarulo A, Werz O, Banoglu E, Çalışkan B. Synthesis and biological evaluation of C(5)-substituted derivatives of leukotriene biosynthesis inhibitor BRP-7. European Journal of Medicinal Chemistry. 122: 510-519. PMID 27423639 DOI: 10.1016/J.Ejmech.2016.07.004  0.809
2016 Banoglu E, Çelikoğlu E, Völker S, Olgaç A, Gerstmeier J, Garscha U, Çalışkan B, Schubert US, Carotti A, Macchiarulo A, Werz O. 4,5-Diarylisoxazol-3-carboxylic acids: A new class of leukotriene biosynthesis inhibitors potentially targeting 5-lipoxygenase-activating protein (FLAP). European Journal of Medicinal Chemistry. 113: 1-10. PMID 26922224 DOI: 10.1016/J.Ejmech.2016.02.027  0.84
2014 Pirol ŞC, Çalişkan B, Durmaz I, Atalay R, Banoglu E. Synthesis and preliminary mechanistic evaluation of 5-(p-tolyl)-1-(quinolin-2-yl)pyrazole-3-carboxylic acid amides with potent antiproliferative activity on human cancer cell lines European Journal of Medicinal Chemistry. 87: 140-149. PMID 25247770 DOI: 10.1016/J.Ejmech.2014.09.056  0.771
2014 Alaşalvar C, Soylu MS, Ünver H, Ocak İskeleli N, Yildiz M, Çiftçi M, Banoğlu E. Crystal structure and DFT calculations of 5-(4-Chlorophenyl)-1-(6-methoxypyridazin-3-yl)-1H-pyrazole-3-carboxylic acid. Spectrochimica Acta. Part a, Molecular and Biomolecular Spectroscopy. 132: 555-62. PMID 24892534 DOI: 10.1016/J.Saa.2014.05.014  0.353
2014 Baytas SN, Inceler N, Yilmaz A, Olgac A, Menevse S, Banoglu E, Hamel E, Bortolozzi R, Viola G. Synthesis, biological evaluation and molecular docking studies of trans-indole-3-acrylamide derivatives, a new class of tubulin polymerization inhibitors. Bioorganic & Medicinal Chemistry. 22: 3096-104. PMID 24816066 DOI: 10.1016/J.Bmc.2014.04.027  0.826
2014 Pergola C, Gerstmeier J, Mönch B, Çalışkan B, Luderer S, Weinigel C, Barz D, Maczewsky J, Pace S, Rossi A, Sautebin L, Banoglu E, Werz O. The novel benzimidazole derivative BRP-7 inhibits leukotriene biosynthesis in vitro and in vivo by targeting 5-lipoxygenase-activating protein (FLAP). British Journal of Pharmacology. 171: 3051-64. PMID 24641614 DOI: 10.1111/Bph.12625  0.511
2014 Sardella R, Levent S, Ianni F, Çalişkan B, Gerstmeier J, Pergola C, Werz O, Banoglu E, Natalini B. Chromatographic separation and biological evaluation of benzimidazole derivative enantiomers as inhibitors of leukotriene biosynthesis Journal of Pharmaceutical and Biomedical Analysis. 89: 88-92. PMID 24270288 DOI: 10.1016/J.Jpba.2013.10.039  0.73
2013 Levent S, Çalışkan B, Çiftçi M, Özkan Y, Yenicesu I, Ünver H, Banoglu E. Pyrazole derivatives as inhibitors of arachidonic acid-induced platelet aggregation. European Journal of Medicinal Chemistry. 64: 42-53. PMID 23639653 DOI: 10.1016/J.Ejmech.2013.03.048  0.769
2013 Calışkan B, Banoglu E. Overview of recent drug discovery approaches for new generation leukotriene A4 hydrolase inhibitors. Expert Opinion On Drug Discovery. 8: 49-63. PMID 23095029 DOI: 10.1517/17460441.2013.735228  0.759
2012 Eren G, Macchiarulo A, Banoglu E. From Molecular Docking to 3D-Quantitative Structure-Activity Relationships (3D-QSAR): Insights into the Binding Mode of 5-Lipoxygenase Inhibitors. Molecular Informatics. 31: 123-34. PMID 27476957 DOI: 10.1002/Minf.201100101  0.678
2012 Banoglu E, Çalişkan B, Luderer S, Eren G, Özkan Y, Altenhofen W, Weinigel C, Barz D, Gerstmeier J, Pergola C, Werz O. Identification of novel benzimidazole derivatives as inhibitors of leukotriene biosynthesis by virtual screening targeting 5-lipoxygenase-activating protein (FLAP). Bioorganic & Medicinal Chemistry. 20: 3728-41. PMID 22607880 DOI: 10.1016/J.Bmc.2012.04.048  0.838
2012 Çalışkan B, Yılmaz A, Evren İ, Menevşe S, Uludag O, Banoglu E. Synthesis and evaluation of analgesic, anti-inflammatory, and anticancer activities of new pyrazole-3(5)-carboxylic acid derivatives Medicinal Chemistry Research. 22: 782-793. DOI: 10.1007/S00044-012-0072-4  0.785
2011 Ergün BC, Coban T, Onurdag FK, Banoglu E. Synthesis, antioxidant and antimicrobial evaluation of simple aromatic esters of ferulic acid. Archives of Pharmacal Research. 34: 1251-61. PMID 21910045 DOI: 10.1007/S12272-011-0803-Y  0.452
2011 Calışkan B, Luderer S, Özkan Y, Werz O, Banoglu E. Pyrazol-3-propanoic acid derivatives as novel inhibitors of leukotriene biosynthesis in human neutrophils. European Journal of Medicinal Chemistry. 46: 5021-33. PMID 21868137 DOI: 10.1016/J.Ejmech.2011.08.009  0.828
2010 Ergün BC, Nuñez MT, Labeaga L, Ledo F, Darlington J, Bain G, Cakir B, Banoglu E. Synthesis of 1,5-diarylpyrazol-3-propanoic acids towards inhibition of cyclooxygenase-1/2 activity and 5-lipoxygenase-mediated LTB4 formation. Arzneimittel-Forschung. 60: 497-505. PMID 20863006 DOI: 10.1055/S-0031-1296318  0.557
2010 Eren G, Unlü S, Nuñez MT, Labeaga L, Ledo F, Entrena A, Banoğlu E, Costantino G, Sahin MF. Synthesis, biological evaluation, and docking studies of novel heterocyclic diaryl compounds as selective COX-2 inhibitors. Bioorganic & Medicinal Chemistry. 18: 6367-76. PMID 20692174 DOI: 10.1016/J.Bmc.2010.07.009  0.536
2009 Dündar Y, Unlü S, Banoğlu E, Entrena A, Costantino G, Nuñez MT, Nunez MT, Labeaga L, Ledo F, Sahin MF, Noyanalpan N. Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors. European Journal of Medicinal Chemistry. 44: 1830-7. PMID 19084295 DOI: 10.1016/J.Ejmech.2008.10.039  0.564
2009 Dündar Y, Ünlü S, Banoğlu E, Entrena A, Costantino G, Nunez M, Ledo F, Fethi Şahin M, Noyanalpan N. Corrigendum to “Synthesis and biological evaluation of 4,5-diphenyloxazolone derivatives on route towards selective COX-2 inhibitors” [Eur. J. Med. Chem. 44 (2009) 1830–1837] European Journal of Medicinal Chemistry. 44: 4785. DOI: 10.1016/J.Ejmech.2009.05.020  0.325
2009 Önkol T, Banoglu E, Dündar Y, Küpeli E, Şahin MF. Amide derivatives of [6-acyl-2-benzothiazolinon-3-yl] acetic acids as potential analgesic and anti-inflammatory compounds Medicinal Chemistry Research. 19: 11-24. DOI: 10.1007/S00044-009-9168-X  0.487
2009 Duendar Y, Uenlue S, Banoglu E, Entrena A, Costantino G, Nunez M, Ledo F, Sahin MF, Noyanalpan N. ChemInform Abstract: Synthesis and Biological Evaluation of 4,5-Diphenyloxazolone Derivatives on Route Towards Selective COX-2 Inhibitors. Cheminform. 40. DOI: 10.1002/CHIN.200934123  0.317
2008 Caliskan-Ergün B, Süküroğlu M, Coban T, Banoğlu E, Suzen S. Screening and evaluation of antioxidant activity of some pyridazine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry. 23: 225-9. PMID 18343908 DOI: 10.1080/14756360701475167  0.431
2007 Unlü S, Banoglu E, Ito S, Niiya T, Eren G, Okçelik B, Sahin MF. Synthesis, characterization and preliminary screening of regioisomeric 1-(3-pyridazinyl)-3-arylpyrazole and 1-(3-pyridazinyl)-5-arylpyrazole derivatives towards cyclooxygenase inhibition. Journal of Enzyme Inhibition and Medicinal Chemistry. 22: 351-61. PMID 17674817 DOI: 10.1080/14756360601073468  0.43
2007 Şüküroğlu M, Çalişkan-Ergün B, Das-Evcimen N, Sarikaya M, Banoğlu E, Suzen S. Screening and evaluation of rat kidney aldose reductase inhibitory activity of some pyridazine derivatives Medicinal Chemistry Research. 15: 443-451. DOI: 10.1007/S00044-006-0021-1  0.43
2006 Süküroglu M, Küpeli E, Banoğlu E, Unlü S, Yeşilada E, Sahin MF. Synthesis and analgesic activity of some 4,6-disubstituted-3(2H)-pyridazinone derivatives. Arzneimittel-Forschung. 56: 337-45. PMID 16821644 DOI: 10.1055/S-0031-1296731  0.423
2005 Süküroglu M, Caliskan Ergün B, Unlü S, Sahin MF, Küpeli E, Yesilada E, Banoglu E. Synthesis, analgesic, and anti-inflammatory activities of [6-(3,5-dimethyl-4-chloropyrazole-1-yl)-3(2H)-pyridazinon-2-yl]acetamides. Archives of Pharmacal Research. 28: 509-17. PMID 15974435 DOI: 10.1007/Bf02977751  0.463
2004 Banoglu E, Akoğlu C, Unlü S, Küpeli E, Yeşilada E, Sahin MF. Amide derivatives of [6-(5-methyl-3-phenylpyrazole-1-yl)-3(2H)-pyridazinone-2-yl]acetic acids as potential analgesic and anti-inflammatory compounds. Archiv Der Pharmazie. 337: 7-14. PMID 14760622 DOI: 10.1002/Ardp.200200738  0.521
2003 Okçelik B, Unlü S, Banoglu E, Küpeli E, Yeşilada E, Sahin MF. Investigations of new pyridazinone derivatives for the synthesis of potent analgesic and anti-inflammatory compounds with cyclooxygenase inhibitory activity. Archiv Der Pharmazie. 336: 406-12. PMID 14528488 DOI: 10.1002/Ardp.200300778  0.507
2003 Banoglu E, Okçelik B, Kupeli E, Unlü S, Yeşilada E, Amat M, Caturla JF, Sahin MF. Amide derivatives of [5-chloro-6-(2-chloro/fluorobenzoyl)-2-benzoxazolinone-3-yl]acetic acids as potential analgesic and anti-inflammatory compounds. Archiv Der Pharmazie. 336: 251-7. PMID 12916060 DOI: 10.1002/Ardp.200300723  0.511
2002 Banoglu E, King RS. Sulfation of indoxyl by human and rat aryl (phenol) sulfotransferases to form indoxyl sulfate European Journal of Drug Metabolism and Pharmacokinetics. 27: 135-140. PMID 12064372 DOI: 10.1007/Bf03190428  0.346
2001 Banoglu E, Jha GG, King RS. Hepatic microsomal metabolism of indole to indoxyl, a precursor of indoxyl sulfate European Journal of Drug Metabolism and Pharmacokinetics. 26: 235-240. PMID 11808865 DOI: 10.1007/Bf03226377  0.314
2001 Banoglu E. Current status of the cytosolic sulfotransferases in the metabolic activation of promutagens and procarcinogens. Current Drug Metabolism. 1: 1-30. PMID 11467078 DOI: 10.2174/1389200003339234  0.361
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