| Year |
Citation |
Score |
| 2024 |
Radka CD, Frank MW, Simmons TS, Johnson CN, Rosch JW, Rock CO. oleate hydratase produces ligands that activate host PPARα. Frontiers in Cellular and Infection Microbiology. 14: 1352810. PMID 38601738 DOI: 10.3389/fcimb.2024.1352810 |
0.694 |
|
| 2024 |
Strange N, Luu L, Ong V, Wee BA, Phillips MJA, McCaughey L, Steele JR, Barlow CK, Cranfield CG, Myers G, Mazraani R, Rock C, Timms P, Huston WM. HtrA, fatty acids, and membrane protein interplay in to impact stress response and trigger early cellular exit. Journal of Bacteriology. e0037123. PMID 38445896 DOI: 10.1128/jb.00371-23 |
0.355 |
|
| 2024 |
Radka CD, Rock CO. Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis. Journal of Structural Biology. 216: 108065. PMID 38310992 DOI: 10.1016/j.jsb.2024.108065 |
0.694 |
|
| 2024 |
Radka CD, Grace CR, Hasdemir HS, Li Y, Rodriguez CC, Rodrigues P, Oldham ML, Qayyum MZ, Pitre A, MacCain WJ, Kalathur RC, Tajkhorshid E, Rock CO. The carboxy terminus causes interfacial assembly of oleate hydratase on a membrane bilayer. The Journal of Biological Chemistry. 105627. PMID 38211817 DOI: 10.1016/j.jbc.2024.105627 |
0.69 |
|
| 2023 |
Zhu M, Frank MW, Radka CD, Jeanfavre S, Tse MW, Pacheco JA, Pierce K, Deik A, Xu J, Hussain S, Hussain FA, Xulu N, Khan N, Pillay V, Dong KL, ... ... Rock CO, et al. Vaginal fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment. Biorxiv : the Preprint Server For Biology. PMID 38234804 DOI: 10.1101/2023.12.30.573720 |
0.748 |
|
| 2023 |
Subramanian C, Yun MK, Frank MM, Rock CO. Lysophosphatidylglycerol (LPG) phospholipase D maintains membrane homeostasis in Staphylococcus aureus by converting LPG to lysophosphatidic acid. The Journal of Biological Chemistry. 104863. PMID 37236358 DOI: 10.1016/j.jbc.2023.104863 |
0.341 |
|
| 2023 |
Whaley SG, Frank MW, Rock CO. A short-chain acyl-CoA synthetase that supports branched-chain fatty acid synthesis in Staphylococcus aureus. The Journal of Biological Chemistry. 103036. PMID 36806679 DOI: 10.1016/j.jbc.2023.103036 |
0.354 |
|
| 2022 |
Radka CD, Miller DJ, Frank MW, Rock CO. Biochemical characterization of the first step in sulfonolipid biosynthesis in Alistipes finegoldii. The Journal of Biological Chemistry. 102195. PMID 35760102 DOI: 10.1016/j.jbc.2022.102195 |
0.759 |
|
| 2022 |
Radka CD, Rock CO. Mining Fatty Acid Biosynthesis for New Antimicrobials. Annual Review of Microbiology. PMID 35650664 DOI: 10.1146/annurev-micro-041320-110408 |
0.733 |
|
| 2022 |
Subramanian C, Cuypers MG, Radka CD, White SW, Rock CO. Domain architecture and catalysis of the Staphylococcus aureus fatty acid kinase. The Journal of Biological Chemistry. 101993. PMID 35490779 DOI: 10.1016/j.jbc.2022.101993 |
0.74 |
|
| 2021 |
Radka CD, Batte JL, Frank MW, Rosch JW, Rock CO. Oleate Hydratase (OhyA) Is a Virulence Determinant in Staphylococcus aureus. Microbiology Spectrum. e0154621. PMID 34817231 DOI: 10.1128/Spectrum.01546-21 |
0.735 |
|
| 2021 |
Whaley SG, Radka CD, Subramanian C, Frank MW, Rock CO. Malonyl-acyl carrier protein decarboxylase activity promotes fatty acid and cell envelope biosynthesis in Proteobacteria. The Journal of Biological Chemistry. 101434. PMID 34801557 DOI: 10.1016/j.jbc.2021.101434 |
0.766 |
|
| 2021 |
Frank MW, Whaley SG, Rock CO. Branched-chain amino acid metabolism controls membrane phospholipid structure in Staphylococcus aureus. The Journal of Biological Chemistry. 297: 101255. PMID 34592315 DOI: 10.1016/j.jbc.2021.101255 |
0.366 |
|
| 2021 |
Aggarwal SD, Gullett JM, Fedder T, Safi JPF, Rock CO, Hiller NL. Competence-Associated Peptide BriC Alters Fatty Acid Biosynthesis in Streptococcus pneumoniae. Msphere. 6: e0014521. PMID 34192504 DOI: 10.1128/mSphere.00145-21 |
0.341 |
|
| 2020 |
Radka CD, Batte JL, Frank MW, Young BM, Rock CO. Structure and mechanism of oleate hydratase (OhyA). The Journal of Biological Chemistry. PMID 33376139 DOI: 10.1074/jbc.RA120.016818 |
0.754 |
|
| 2020 |
Echlin H, Frank M, Rock C, Rosch JW. Role of the pyruvate metabolic network on carbohydrate metabolism and virulence in Streptococcus pneumoniae. Molecular Microbiology. PMID 32495474 DOI: 10.1111/Mmi.14557 |
0.332 |
|
| 2020 |
Frank MW, Yao J, Batte JL, Gullett JM, Subramanian C, Rosch JW, Rock CO. Host Fatty Acid Utilization by Staphylococcus aureus at the Infection Site. Mbio. 11. PMID 32430471 DOI: 10.1128/Mbio.00920-20 |
0.442 |
|
| 2020 |
Radka CD, Frank MW, Yao J, Seetharaman J, Miller DJ, Rock CO. The genome of a Bacteroidetes inhabitant of the human gut encodes a structurally distinct enoyl-acyl carrier protein reductase (FabI). The Journal of Biological Chemistry. PMID 32317282 DOI: 10.1074/Jbc.Ra120.013336 |
0.748 |
|
| 2020 |
Subramanian C, Yao J, Frank MW, Rock CO, Jackowski S. A pantothenate kinase-deficient mouse model reveals a gene expression program associated with brain coenzyme a reduction. Biochimica Et Biophysica Acta. Molecular Basis of Disease. 165663. PMID 31918006 DOI: 10.1016/J.Bbadis.2020.165663 |
0.308 |
|
| 2020 |
Whaley SG, Rock CO. Alternate fatty acid synthesis initiation in Escherichia coli The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06665 |
0.438 |
|
| 2020 |
Gullett J, Cuypers M, Frank M, Royappa G, Subramanian C, White S, Rock CO. Structural Basis for the Utilization of Host Fatty Acids by Bacterial Fatty Acid Binding Proteins The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04016 |
0.455 |
|
| 2020 |
Radka CD, Frank MW, Yao J, Jayaraman S, Miller DJ, Rock CO. Unique Aspects of Lipid Metabolism in the Human Gut Microbiome The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03425 |
0.717 |
|
| 2019 |
Radka CD, Frank MW, Rock CO, Yao J. Fatty acid activation and utilization by Alistipes finegoldii, a representative Bacteroidetes resident of the human gut microbiome. Molecular Microbiology. PMID 31876062 DOI: 10.1111/Mmi.14445 |
0.773 |
|
| 2019 |
Gullett JM, Cuypers MG, Frank MW, White SW, Rock CO. A fatty acid binding protein of facilitates the acquisition of host polyunsaturated fatty acids. The Journal of Biological Chemistry. PMID 31530637 DOI: 10.1074/Jbc.Ra119.010659 |
0.473 |
|
| 2019 |
Párraga Solórzano PK, Yao J, Rock CO, Kehl-Fie TE. Disruption of Glycolysis by Nutritional Immunity Activates a Two-Component System That Coordinates a Metabolic and Antihost Response by Staphylococcus aureus. Mbio. 10. PMID 31387906 DOI: 10.1128/Mbio.01321-19 |
0.348 |
|
| 2019 |
Subramanian C, Frank MW, Batte JL, Whaley SG, Rock CO. Oleate hydratase from protects against palmitoleic acid, the major antimicrobial fatty acid produced by mammalian skin. The Journal of Biological Chemistry. PMID 31018965 DOI: 10.1074/Jbc.Ra119.008439 |
0.455 |
|
| 2019 |
Yao J, Subramanian C, Rock CO, Jackowski S. Human Pantothenate Kinase 4 (PANK4) is a Pseudo-Pantothenate Kinase. Protein Science : a Publication of the Protein Society. PMID 30927326 DOI: 10.1002/Pro.3611 |
0.316 |
|
| 2018 |
Cuypers MG, Subramanian C, Gullett JM, Frank MW, White SW, Rock CO. Acyl chain selectivity and physiological roles of fatty acid binding proteins. The Journal of Biological Chemistry. PMID 30429218 DOI: 10.1074/Jbc.Ra118.006160 |
0.454 |
|
| 2018 |
Sharma LK, Subramanian C, Yun MK, Frank MW, White SW, Rock CO, Lee RE, Jackowski S. A therapeutic approach to pantothenate kinase associated neurodegeneration. Nature Communications. 9: 4399. PMID 30352999 DOI: 10.1038/S41467-018-06703-2 |
0.324 |
|
| 2018 |
Yao J, Rock CO. Therapeutic Targets in Chlamydial Fatty Acid and Phospholipid Synthesis. Frontiers in Microbiology. 9: 2291. PMID 30319589 DOI: 10.3389/Fmicb.2018.02291 |
0.457 |
|
| 2018 |
Griffith EC, Wallace MJ, Wu Y, Kumar G, Gajewski S, Jackson P, Phelps GA, Zheng Z, Rock CO, Lee RE, White SW. The Structural and Functional Basis for Recurring Sulfa Drug Resistance Mutations inStaphylococcus aureusDihydropteroate Synthase. Frontiers in Microbiology. 9: 1369-1369. DOI: 10.2210/Pdb6Clu/Pdb |
0.34 |
|
| 2018 |
Cuypers MG, Ericson M, Subramanian C, Broussard TC, Miller DJ, White SW, Rock CO. The crystal structure of the Staphylococcus aureus Fatty acid Kinase (Fak) B1 protein loaded with palmitic acid to 1.83 Angstroem resolution Journal of Biological Chemistry. DOI: 10.2210/Pdb5V85/Pdb |
0.397 |
|
| 2018 |
Cuypers MG, Ericson M, Subramanian C, White SW, Rock CO. The residues in the hydrophobic core of Staphylococcus aureus fatty acid kinase B1 determine fatty acid specificity Acta Crystallographica Section A. 74. DOI: 10.1107/S0108767318099567 |
0.425 |
|
| 2017 |
Ericson ME, Subramanian C, Frank MW, Rock CO. Role of Fatty Acid Kinase in Cellular Lipid Homeostasis and SaeRS-Dependent Virulence Factor Expression in Staphylococcus aureus. Mbio. 8. PMID 28765222 DOI: 10.1128/Mbio.00988-17 |
0.384 |
|
| 2017 |
Robertson RM, Yao J, Gajewski S, Kumar G, Martin EW, Rock CO, White SW. A two-helix motif positions the lysophosphatidic acid acyltransferase active site for catalysis within the membrane bilayer. Nature Structural & Molecular Biology. PMID 28714993 DOI: 10.1038/Nsmb.3436 |
0.442 |
|
| 2017 |
Yao J, Rock CO. Exogenous fatty acid metabolism in bacteria. Biochimie. PMID 28668270 DOI: 10.1016/J.Biochi.2017.06.015 |
0.477 |
|
| 2017 |
Arensdorf AM, Dillard ME, Menke JM, Frank MW, Rock CO, Ogden SK. Sonic Hedgehog Activates Phospholipase A2 to Enhance Smoothened Ciliary Translocation. Cell Reports. 19: 2074-2087. PMID 28591579 DOI: 10.1016/J.Celrep.2017.05.033 |
0.353 |
|
| 2017 |
Honsa ES, Cooper VS, Mhaissen MN, Frank M, Shaker J, Iverson A, Rubnitz J, Hayden RT, Lee RE, Rock CO, Tuomanen EI, Wolf J, Rosch JW. RelA Mutant Enterococcus faecium with Multiantibiotic Tolerance Arising in an Immunocompromised Host. Mbio. 8. PMID 28049149 DOI: 10.1128/Mbio.02124-16 |
0.311 |
|
| 2016 |
Echlin H, Frank MW, Iverson A, Chang TC, Johnson MD, Rock CO, Rosch JW. Pyruvate Oxidase as a Critical Link between Metabolism and Capsule Biosynthesis in Streptococcus pneumoniae. Plos Pathogens. 12: e1005951. PMID 27760231 DOI: 10.1371/Journal.Ppat.1005951 |
0.332 |
|
| 2016 |
Yao J, Ericson ME, Frank MW, Rock CO. Enoyl-Acyl Carrier Protein Reductase I (FabI) is Essential for the Intracellular Growth of Listeria monocytogenes. Infection and Immunity. PMID 27736774 DOI: 10.1128/Iai.00647-16 |
0.444 |
|
| 2016 |
Yao J, Rock CO. Bacterial fatty acid metabolism in modern antibiotic discovery. Biochimica Et Biophysica Acta. PMID 27668701 DOI: 10.1016/J.Bbalip.2016.09.014 |
0.425 |
|
| 2016 |
Subramanian C, Yun MK, Yao J, Sharma LK, Lee RE, White SW, Jackowski S, Rock CO. Allosteric Regulation of Mammalian Pantothenate Kinase. The Journal of Biological Chemistry. PMID 27555321 DOI: 10.1074/Jbc.M116.748061 |
0.371 |
|
| 2016 |
Yao J, Rock CO. Resistance Mechanisms and the Future of Bacterial Enoyl-Acyl Carrier Protein Reductase (FabI) Antibiotics. Cold Spring Harbor Perspectives in Medicine. 6. PMID 26931811 DOI: 10.1101/Cshperspect.A027045 |
0.323 |
|
| 2016 |
Broussard TC, Miller DJ, Jackson P, Nourse A, White SW, Rock CO. Biochemical roles for conserved residues in the bacterial fatty acid binding protein family. The Journal of Biological Chemistry. PMID 26774272 DOI: 10.1074/Jbc.M115.706820 |
0.484 |
|
| 2015 |
Yao J, Bruhn DF, Frank MW, Lee RE, Rock CO. Activation of exogenous fatty acids to acyl-acyl carrier protein cannot bypass FabI inhibition in Neisseria. The Journal of Biological Chemistry. PMID 26567338 DOI: 10.1074/Jbc.M115.699462 |
0.465 |
|
| 2015 |
Yao J, Dodson VJ, Frank MW, Rock CO. Chlamydia trachomatis Scavenges Host Fatty Acids for Phospholipid Synthesis via an Acyl-Acyl Carrier Protein Synthetase. The Journal of Biological Chemistry. 290: 22163-73. PMID 26195634 DOI: 10.1074/Jbc.M115.671008 |
0.469 |
|
| 2015 |
Wallace J, Bowlin NO, Mills DM, Saenkham P, Kwasny SM, Opperman TJ, Williams JD, Rock CO, Bowlin TL, Moir DT. Discovery of bacterial fatty acid synthase type II inhibitors using a novel cellular bioluminescent reporter assay. Antimicrobial Agents and Chemotherapy. 59: 5775-87. PMID 26169404 DOI: 10.1128/Aac.00686-15 |
0.377 |
|
| 2015 |
Yao J, Cherian PT, Frank MW, Rock CO. Chlamydia trachomatis Relies on Autonomous Phospholipid Synthesis for Membrane Biogenesis. The Journal of Biological Chemistry. PMID 25995447 DOI: 10.1074/Jbc.M115.657148 |
0.411 |
|
| 2015 |
Yao J, Rock CO. How bacterial pathogens eat host lipids: implications for the development of fatty acid synthesis therapeutics. The Journal of Biological Chemistry. 290: 5940-6. PMID 25648887 DOI: 10.1074/Jbc.R114.636241 |
0.453 |
|
| 2015 |
Parsons JB, Frank MW, Eleveld MJ, Schalkwijk J, Broussard TC, de Jonge MI, Rock CO. A thioesterase bypasses the requirement for exogenous fatty acids in the plsX deletion of Streptococcus pneumoniae. Molecular Microbiology. 96: 28-41. PMID 25534847 DOI: 10.1111/mmi.12916 |
0.341 |
|
| 2015 |
Yao J, Dodson VJ, Frank MW, Rock CO. Chlamydia trachomatis scavenges host fatty acids for phospholipid synthesis via an acyl-acyl carrier protein synthetase Journal of Biological Chemistry. 290: 22163-22173. DOI: 10.1074/jbc.M115.671008 |
0.341 |
|
| 2015 |
Jackowski S, Rock CO. CoA regulation and metabolic control The Biochemist. 37: 4-8. DOI: 10.1042/bio03701004 |
0.328 |
|
| 2014 |
Parsons JB, Broussard TC, Bose JL, Rosch JW, Jackson P, Subramanian C, Rock CO. Identification of a two-component fatty acid kinase responsible for host fatty acid incorporation by Staphylococcus aureus. Proceedings of the National Academy of Sciences of the United States of America. 111: 10532-7. PMID 25002480 DOI: 10.1073/Pnas.1408797111 |
0.376 |
|
| 2014 |
Yao J, Abdelrahman YM, Robertson RM, Cox JV, Belland RJ, White SW, Rock CO. Type II fatty acid synthesis is essential for the replication of Chlamydia trachomatis. The Journal of Biological Chemistry. 289: 22365-76. PMID 24958721 DOI: 10.1074/Jbc.M114.584185 |
0.454 |
|
| 2014 |
Zheng Z, Parsons JB, Tangallapally R, Zhang W, Rock CO, Lee RE. Discovery of novel bacterial elongation condensing enzyme inhibitors by virtual screening. Bioorganic & Medicinal Chemistry Letters. 24: 2585-8. PMID 24755430 DOI: 10.1016/j.bmcl.2014.03.033 |
0.3 |
|
| 2014 |
Parsons JB, Frank MW, Jackson P, Subramanian C, Rock CO. Incorporation of extracellular fatty acids by a fatty acid kinase-dependent pathway in Staphylococcus aureus. Molecular Microbiology. 92: 234-45. PMID 24673884 DOI: 10.1111/mmi.12556 |
0.369 |
|
| 2014 |
Yun MK, Hoagland D, Kumar G, Waddell MB, Rock CO, Lee RE, White SW. The identification, analysis and structure-based development of novel inhibitors of 6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase. Bioorganic & Medicinal Chemistry. 22: 2157-65. PMID 24613625 DOI: 10.1016/J.Bmc.2014.02.022 |
0.341 |
|
| 2013 |
Parsons JB, Yao J, Jackson P, Frank M, Rock CO. Phosphatidylglycerol homeostasis in glycerol-phosphate auxotrophs of Staphylococcus aureus. Bmc Microbiology. 13: 260. PMID 24238430 DOI: 10.1186/1471-2180-13-260 |
0.362 |
|
| 2013 |
Yao J, Maxwell JB, Rock CO. Resistance to AFN-1252 arises from missense mutations in Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI). The Journal of Biological Chemistry. 288: 36261-71. PMID 24189061 DOI: 10.1074/Jbc.M113.512905 |
0.358 |
|
| 2013 |
Parsons JB, Frank MW, Rosch JW, Rock CO. Staphylococcus aureus fatty acid auxotrophs do not proliferate in mice. Antimicrobial Agents and Chemotherapy. 57: 5729-32. PMID 23979734 DOI: 10.1128/Aac.01038-13 |
0.33 |
|
| 2013 |
Parsons JB, Rock CO. Bacterial lipids: metabolism and membrane homeostasis. Progress in Lipid Research. 52: 249-76. PMID 23500459 DOI: 10.1016/j.plipres.2013.02.002 |
0.33 |
|
| 2013 |
Jackowski S, Rock CO. Preface: phospholipids and phospholipid metabolism Biochimica Et Biophysica Acta. 1831: 469-470. PMID 23369660 DOI: 10.1016/J.Bbalip.2013.01.001 |
0.313 |
|
| 2013 |
Yao J, Rock CO. Phosphatidic acid synthesis in bacteria. Biochimica Et Biophysica Acta. 1831: 495-502. PMID 22981714 DOI: 10.1016/J.Bbalip.2012.08.018 |
0.373 |
|
| 2012 |
Parsons JB, Yao J, Frank MW, Jackson P, Rock CO. Membrane disruption by antimicrobial fatty acids releases low-molecular-weight proteins from Staphylococcus aureus. Journal of Bacteriology. 194: 5294-304. PMID 22843840 DOI: 10.1128/Jb.00743-12 |
0.381 |
|
| 2012 |
Zhang YM, Rock CO. Will the initiator of fatty acid synthesis in Pseudomonas aeruginosa please stand up? Journal of Bacteriology. 194: 5159-61. PMID 22821980 DOI: 10.1128/Jb.01198-12 |
0.445 |
|
| 2012 |
Cherian PT, Yao J, Leonardi R, Maddox MM, Luna VA, Rock CO, Lee RE. Acyl-sulfamates target the essential glycerol-phosphate acyltransferase (PlsY) in Gram-positive bacteria. Bioorganic & Medicinal Chemistry. 20: 4985-94. PMID 22795901 DOI: 10.1016/J.Bmc.2012.06.029 |
0.452 |
|
| 2012 |
Leonardi R, Subramanian C, Jackowski S, Rock CO. Cancer-associated isocitrate dehydrogenase mutations inactivate NADPH-dependent reductive carboxylation. The Journal of Biological Chemistry. 287: 14615-20. PMID 22442146 DOI: 10.1074/Jbc.C112.353946 |
0.33 |
|
| 2011 |
Taherbhoy AM, Tait SW, Kaiser SE, Williams AH, Deng A, Nourse A, Hammel M, Kurinov I, Rock CO, Green DR, Schulman BA. Atg8 transfer from Atg7 to Atg3: a distinctive E1-E2 architecture and mechanism in the autophagy pathway. Molecular Cell. 44: 451-61. PMID 22055190 DOI: 10.1016/J.Molcel.2011.08.034 |
0.326 |
|
| 2011 |
Parsons JB, Frank MW, Subramanian C, Saenkham P, Rock CO. Metabolic basis for the differential susceptibility of Gram-positive pathogens to fatty acid synthesis inhibitors. Proceedings of the National Academy of Sciences of the United States of America. 108: 15378-83. PMID 21876172 DOI: 10.1073/pnas.1109208108 |
0.358 |
|
| 2011 |
Parsons JB, Rock CO. Is bacterial fatty acid synthesis a valid target for antibacterial drug discovery? Current Opinion in Microbiology. 14: 544-9. PMID 21862391 DOI: 10.1016/j.mib.2011.07.029 |
0.363 |
|
| 2011 |
Kingston AW, Subramanian C, Rock CO, Helmann JD. A σW-dependent stress response in Bacillus subtilis that reduces membrane fluidity. Molecular Microbiology. 81: 69-79. PMID 21542858 DOI: 10.1111/J.1365-2958.2011.07679.X |
0.408 |
|
| 2010 |
Zhang YM, Rock CO. A rainbow coalition of lipid transcriptional regulators. Molecular Microbiology. 78: 5-8. PMID 20941840 DOI: 10.1111/J.1365-2958.2010.07349.X |
0.446 |
|
| 2010 |
Leonardi R, Zhang YM, Yun MK, Zhou R, Zeng FY, Lin W, Cui J, Chen T, Rock CO, White SW, Jackowski S. Modulation of pantothenate kinase 3 activity by small molecules that interact with the substrate/allosteric regulatory domain. Chemistry & Biology. 17: 892-902. PMID 20797618 DOI: 10.1016/J.Chembiol.2010.06.006 |
0.38 |
|
| 2010 |
Miller DJ, Zhang YM, Subramanian C, Rock CO, White SW. Structural basis for the transcriptional regulation of membrane lipid homeostasis. Nature Structural & Molecular Biology. 17: 971-5. PMID 20639888 DOI: 10.1038/Nsmb.1847 |
0.393 |
|
| 2010 |
Leonardi R, Rehg JE, Rock CO, Jackowski S. Pantothenate kinase 1 is required to support the metabolic transition from the fed to the fasted state Plos One. 5. PMID 20559429 DOI: 10.1371/Journal.Pone.0011107 |
0.401 |
|
| 2010 |
Subramanian C, Rock CO, Zhang YM. DesT coordinates the expression of anaerobic and aerobic pathways for unsaturated fatty acid biosynthesis in Pseudomonas aeruginosa Journal of Bacteriology. 192: 280-285. PMID 19880602 DOI: 10.1128/Jb.00404-09 |
0.452 |
|
| 2009 |
Singh AK, Zhang YM, Zhu K, Subramanian C, Li Z, Jayaswal RK, Gatto C, Rock CO, Wilkinson BJ. FabH selectivity for anteiso branched-chain fatty acid precursors in low-temperature adaptation in Listeria monocytogenes. Fems Microbiology Letters. 301: 188-92. PMID 19863661 DOI: 10.1111/J.1574-6968.2009.01814.X |
0.449 |
|
| 2009 |
Zhu K, Zhang YM, Rock CO. Transcriptional regulation of membrane lipid homeostasis in Escherichia coli. The Journal of Biological Chemistry. 284: 34880-8. PMID 19854834 DOI: 10.1074/Jbc.M109.068239 |
0.45 |
|
| 2009 |
Rock CO. Opening a new path to lipoic acid. Journal of Bacteriology. 191: 6782-4. PMID 19734307 DOI: 10.1128/Jb.01151-09 |
0.441 |
|
| 2009 |
Leonardi R, Frank MW, Jackson PD, Rock CO, Jackowski S. Elimination of the CDP-ethanolamine pathway disrupts hepatic lipid homeostasis. The Journal of Biological Chemistry. 284: 27077-89. PMID 19666474 DOI: 10.1074/Jbc.M109.031336 |
0.417 |
|
| 2009 |
Jerga A, Rock CO. Acyl-Acyl carrier protein regulates transcription of fatty acid biosynthetic genes via the FabT repressor in Streptococcus pneumoniae. The Journal of Biological Chemistry. 284: 15364-8. PMID 19376778 DOI: 10.1074/Jbc.C109.002410 |
0.433 |
|
| 2009 |
Wu BN, Zhang YM, Rock CO, Zheng JJ. Structural modification of acyl carrier protein by butyryl group. Protein Science : a Publication of the Protein Society. 18: 240-6. PMID 19177367 DOI: 10.1002/Pro.11 |
0.457 |
|
| 2009 |
Jerga A, Miller DJ, White SW, Rock CO. Molecular determinants for interfacial binding and conformational change in a soluble diacylglycerol kinase. The Journal of Biological Chemistry. 284: 7246-54. PMID 19112175 DOI: 10.1074/Jbc.M805962200 |
0.363 |
|
| 2009 |
Zhang YM, Rock CO. Transcriptional regulation in bacterial membrane lipid synthesis. Journal of Lipid Research. 50: S115-9. PMID 18941141 DOI: 10.1194/jlr.R800046-JLR200 |
0.361 |
|
| 2009 |
Jerga A, Rock CO. Long‐chain acyl‐acyl carrier protein activates transcriptional regulation of fatty acid biosynthesis in
Streptococcus pneumoniae The Faseb Journal. 23. DOI: 10.1096/FASEBJ.23.1_SUPPLEMENT.689.11 |
0.324 |
|
| 2008 |
Cronan JE, Rock CO. Biosynthesis of Membrane Lipids. Ecosal Plus. 3. PMID 26443744 DOI: 10.1128/ecosalplus.3.6.4 |
0.371 |
|
| 2008 |
Grimes KD, Lu YJ, Zhang YM, Luna VA, Hurdle JG, Carson EI, Qi J, Kudrimoti S, Rock CO, Lee RE. Novel acyl phosphate mimics that target PlsY, an essential acyltransferase in gram-positive bacteria. Chemmedchem. 3: 1936-45. PMID 19016283 DOI: 10.1002/Cmdc.200800218 |
0.372 |
|
| 2008 |
Zhang YM, Frank MW, Zhu K, Mayasundari A, Rock CO. PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosa. The Journal of Biological Chemistry. 283: 28788-94. PMID 18728009 DOI: 10.1074/Jbc.M804555200 |
0.387 |
|
| 2008 |
Miller DJ, Jerga A, Rock CO, White SW. Analysis of the Staphylococcus aureus DgkB structure reveals a common catalytic mechanism for the soluble diacylglycerol kinases. Structure (London, England : 1993). 16: 1036-46. PMID 18611377 DOI: 10.1016/J.Str.2008.03.019 |
0.364 |
|
| 2008 |
Zhang YM, Rock CO. Thematic review series: Glycerolipids. Acyltransferases in bacterial glycerophospholipid synthesis. Journal of Lipid Research. 49: 1867-74. PMID 18369234 DOI: 10.1194/jlr.R800005-JLR200 |
0.395 |
|
| 2008 |
Zhu K, Rock CO. RhlA converts beta-hydroxyacyl-acyl carrier protein intermediates in fatty acid synthesis to the beta-hydroxydecanoyl-beta-hydroxydecanoate component of rhamnolipids in Pseudomonas aeruginosa. Journal of Bacteriology. 190: 3147-54. PMID 18326581 DOI: 10.1128/Jb.00080-08 |
0.385 |
|
| 2007 |
Zhang YM, Zhu K, Frank MW, Rock CO. A Pseudomonas aeruginosa transcription factor that senses fatty acid structure. Molecular Microbiology. 66: 622-32. PMID 17877713 DOI: 10.1111/J.1365-2958.2007.05934.X |
0.463 |
|
| 2007 |
Bum SH, Senisterra G, Rabeh WM, Vedadi M, Leonardi R, Zhang YM, Rock CO, Jackowski S, Park HW. Crystal structures of human pantothenate kinases: Insights into allosteric regulation and mutations linked to a neurodegeneration disorder Journal of Biological Chemistry. 282: 27984-27993. PMID 17631502 DOI: 10.1074/Jbc.M701915200 |
0.348 |
|
| 2007 |
Paoletti L, Lu YJ, Schujman GE, de Mendoza D, Rock CO. Coupling of fatty acid and phospholipid synthesis in Bacillus subtilis. Journal of Bacteriology. 189: 5816-24. PMID 17557823 DOI: 10.1128/Jb.00602-07 |
0.481 |
|
| 2007 |
Jerga A, Lu YJ, Schujman GE, de Mendoza D, Rock CO. Identification of a soluble diacylglycerol kinase required for lipoteichoic acid production in Bacillus subtilis. The Journal of Biological Chemistry. 282: 21738-45. PMID 17535816 DOI: 10.1074/Jbc.M703536200 |
0.434 |
|
| 2007 |
Yun MK, Nourse A, White SW, Rock CO, Heath RJ. Crystal structure and allosteric regulation of the cytoplasmic Escherichia coli L-asparaginase I. Journal of Molecular Biology. 369: 794-811. PMID 17451745 DOI: 10.1016/J.Jmb.2007.03.061 |
0.363 |
|
| 2007 |
Zhang YM, Chohnan S, Virga KG, Stevens RD, Ilkayeva OR, Wenner BR, Bain JR, Newgard CB, Lee RE, Rock CO, Jackowski S. Chemical knockout of pantothenate kinase reveals the metabolic and genetic program responsible for hepatic coenzyme A homeostasis. Chemistry & Biology. 14: 291-302. PMID 17379144 DOI: 10.1016/J.Chembiol.2007.01.013 |
0.385 |
|
| 2007 |
Lu YJ, Zhang F, Grimes KD, Lee RE, Rock CO. Topology and active site of PlsY: the bacterial acylphosphate:glycerol-3-phosphate acyltransferase. The Journal of Biological Chemistry. 282: 11339-46. PMID 17308305 DOI: 10.1074/Jbc.M700374200 |
0.419 |
|
| 2007 |
Leonardi R, Rock CO, Jackowski S, Zhang YM. Activation of human mitochondrial pantothenate kinase 2 by palmitoylcarnitine Proceedings of the National Academy of Sciences of the United States of America. 104: 1494-1499. PMID 17242360 DOI: 10.1073/Pnas.0607621104 |
0.364 |
|
| 2007 |
Rock CO. Regulation and structure of type II fatty acid synthase Chemistry and Physics of Lipids. 149. DOI: 10.1016/J.Chemphyslip.2007.06.021 |
0.393 |
|
| 2006 |
Lu YJ, Zhang YM, Grimes KD, Qi J, Lee RE, Rock CO. Acyl-phosphates initiate membrane phospholipid synthesis in Gram-positive pathogens. Molecular Cell. 23: 765-72. PMID 16949372 DOI: 10.1016/j.molcel.2006.06.030 |
0.381 |
|
| 2006 |
Hong BS, Yun MK, Zhang YM, Chohnan S, Rock CO, White SW, Jackowski S, Park HW, Leonardi R. Prokaryotic Type II and Type III Pantothenate Kinases: The Same Monomer Fold Creates Dimers with Distinct Catalytic Properties Structure. 14: 1251-1261. PMID 16905099 DOI: 10.1016/J.Str.2006.06.008 |
0.363 |
|
| 2006 |
Tian Y, Jackson P, Gunter C, Wang J, Rock CO, Jackowski S. Placental thrombosis and spontaneous fetal death in mice deficient in ethanolamine kinase 2. The Journal of Biological Chemistry. 281: 28438-49. PMID 16861741 DOI: 10.1074/Jbc.M605861200 |
0.311 |
|
| 2006 |
Zhang YM, White SW, Rock CO. Inhibiting bacterial fatty acid synthesis. The Journal of Biological Chemistry. 281: 17541-4. PMID 16648134 DOI: 10.1074/jbc.R600004200 |
0.361 |
|
| 2006 |
Miller DJ, Zhang YM, Rock CO, White SW. Structure of RhlG, an essential beta-ketoacyl reductase in the rhamnolipid biosynthetic pathway of Pseudomonas aeruginosa. The Journal of Biological Chemistry. 281: 18025-32. PMID 16624803 DOI: 10.1074/Jbc.M601687200 |
0.461 |
|
| 2006 |
Zhang YM, Hurlbert J, White SW, Rock CO. Roles of the active site water, histidine 303, and phenylalanine 396 in the catalytic mechanism of the elongation condensing enzyme of streptococcus pneumoniae Journal of Biological Chemistry. 281: 17390-17399. PMID 16618705 DOI: 10.1074/Jbc.M513199200 |
0.387 |
|
| 2006 |
Zhu K, Choi KH, Schweizer HP, Rock CO, Zhang YM. Two aerobic pathways for the formation of unsaturated fatty acids in Pseudomonas aeruginosa Molecular Microbiology. 60: 260-273. PMID 16573679 DOI: 10.1111/J.1365-2958.2006.05088.X |
0.465 |
|
| 2006 |
Courtney HS, Zhang YM, Frank MW, Rock CO. Serum opacity factor, a streptococcal virulence factor that binds to apolipoproteins A-I and A-II and disrupts high density lipoprotein structure. The Journal of Biological Chemistry. 281: 5515-21. PMID 16407233 DOI: 10.1074/Jbc.M512538200 |
0.31 |
|
| 2006 |
Kim P, Zhang YM, Shenoy G, Nguyen QA, Boshoff HI, Manjunatha UH, Goodwin MB, Lonsdale J, Price AC, Miller DJ, Duncan K, White SW, Rock CO, Barry CE, Dowd CS. Structure-activity relationships at the 5-position of thiolactomycin: an intact (5R)-isoprene unit is required for activity against the condensing enzymes from Mycobacterium tuberculosis and Escherichia coli. Journal of Medicinal Chemistry. 49: 159-71. PMID 16392800 DOI: 10.1021/Jm050825P |
0.416 |
|
| 2006 |
Lu YJ, Rock CO. Transcriptional regulation of fatty acid biosynthesis in Streptococcus pneumoniae. Molecular Microbiology. 59: 551-66. PMID 16390449 DOI: 10.1111/J.1365-2958.2005.04951.X |
0.442 |
|
| 2006 |
Zhang YM, Rock CO, Jackowski S. Biochemical properties of human pantothenate kinase 2 isoforms and mutations linked to pantothenate kinase-associated neurodegeneration Journal of Biological Chemistry. 281: 107-114. PMID 16272150 DOI: 10.1074/Jbc.M508825200 |
0.347 |
|
| 2006 |
Virga KG, Zhang YM, Leonardi R, Ivey RA, Hevener K, Park HW, Jackowski S, Rock CO, Lee RE. Structure-activity relationships and enzyme inhibition of pantothenamide-type pantothenate kinase inhibitors. Bioorganic & Medicinal Chemistry. 14: 1007-20. PMID 16213731 DOI: 10.1016/J.Bmc.2005.09.021 |
0.378 |
|
| 2005 |
Zhang YM, Rock CO, Jackowski S. Feedback regulation of murine pantothenate kinase 3 by coenzyme A and coenzyme A thioesters Journal of Biological Chemistry. 280: 32594-32601. PMID 16040613 DOI: 10.1074/Jbc.M506275200 |
0.385 |
|
| 2005 |
Lu Y, White SW, Rock CO. Domain Swapping between Enterococcus faecalis FabN and FabZ Proteins Localizes the Structural Determinants for Isomerase Activity Journal of Biological Chemistry. 280: 30342-30348. PMID 15980063 DOI: 10.1074/Jbc.M504637200 |
0.376 |
|
| 2005 |
Leonardi R, Zhang YM, Rock CO, Jackowski S. Coenzyme A: Back in action Progress in Lipid Research. 44: 125-153. PMID 15893380 DOI: 10.1016/j.plipres.2005.04.001 |
0.348 |
|
| 2005 |
Harvat EM, Zhang YM, Tran CV, Zhang Z, Frank MW, Rock CO, Saier MH. Lysophospholipid flipping across the Escherichia coli inner membrane catalyzed by a transporter (LplT) belonging to the major facilitator superfamily Journal of Biological Chemistry. 280: 12028-12034. PMID 15661733 DOI: 10.1074/Jbc.M414368200 |
0.379 |
|
| 2005 |
Leonardi R, Chohnan S, Zhang YM, Virga KG, Lee RE, Rock CO, Jackowski S. A pantothenate kinase from Staphylococcus aureus refractory to feedback regulation by coenzyme A Journal of Biological Chemistry. 280: 3314-3322. PMID 15548531 DOI: 10.1074/Jbc.M411608200 |
0.453 |
|
| 2004 |
Zhang Y, Lu Y, Rock CO. The reductase steps of the type II fatty acid synthase as antimicrobial targets Lipids. 39: 1055-1060. PMID 15726819 DOI: 10.1007/S11745-004-1330-3 |
0.368 |
|
| 2004 |
Zhang YM, Frank MW, Virga KG, Lee RE, Rock CO, Jackowski S. Acyl carrier protein is a cellular target for the antibacterial action of the pantothenamide class of pantothenate antimetabolites Journal of Biological Chemistry. 279: 50969-50975. PMID 15459190 DOI: 10.1074/jbc.M409607200 |
0.411 |
|
| 2004 |
Kimber MS, Martin F, Lu Y, Houston S, Vedadi M, Dharamsi A, Fiebig KM, Schmid M, Rock CO. The structure of (3R)-hydroxyacyl-acyl carrier protein dehydratase (FabZ) from Pseudomonas aeruginosa. The Journal of Biological Chemistry. 279: 52593-602. PMID 15371447 DOI: 10.1074/Jbc.M408105200 |
0.483 |
|
| 2004 |
Zhang Y, Rock CO. Evaluation of epigallocatechin gallate and related plant polyphenols as inhibitors of the FabG and FabI reductases of bacterial type II fatty-acid synthase. Journal of Biological Chemistry. 279: 30994-31001. PMID 15133034 DOI: 10.1074/Jbc.M403697200 |
0.428 |
|
| 2004 |
Lu YJ, Zhang YM, Rock CO. Product diversity and regulation of type II fatty acid synthases. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 82: 145-55. PMID 15052334 DOI: 10.1139/O03-076 |
0.354 |
|
| 2004 |
Price AC, Zhang YM, Rock CO, White SW. Cofactor-induced conformational rearrangements establish a catalytically competent active site and a proton relay conduit in FabG. Structure (London, England : 1993). 12: 417-28. PMID 15016358 DOI: 10.1016/J.Str.2004.02.008 |
0.382 |
|
| 2003 |
Zhang Y, Wu B, Zheng J, Rock CO. Key Residues Responsible for Acyl Carrier Protein and β-Ketoacyl-Acyl Carrier Protein Reductase (FabG) Interaction Journal of Biological Chemistry. 278: 52935-52943. PMID 14527946 DOI: 10.1074/Jbc.M309874200 |
0.318 |
|
| 2003 |
Price AC, Rock CO, White SW. The 1.3-Angstrom-resolution crystal structure of beta-ketoacyl-acyl carrier protein synthase II from Streptococcus pneumoniae. Journal of Bacteriology. 185: 4136-43. PMID 12837788 DOI: 10.1128/Jb.185.14.4136-4143.2003 |
0.438 |
|
| 2003 |
Yun M, Keshvara L, Park CG, Zhang YM, Dickerson JB, Zheng J, Rock CO, Curran T, Park HW. Crystal structures of the Dab homology domains of mouse disabled 1 and 2. The Journal of Biological Chemistry. 278: 36572-81. PMID 12826668 DOI: 10.1074/Jbc.M304384200 |
0.315 |
|
| 2003 |
Zhang YM, Marrakchi H, White SW, Rock CO. The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase. Journal of Lipid Research. 44: 1-10. PMID 12518017 DOI: 10.1194/JLR.R200016-JLR200 |
0.324 |
|
| 2003 |
Marrakchi H, Dewolf WE, Quinn C, West J, Polizzi BJ, So CY, Holmes DJ, Reed SL, Heath RJ, Payne DJ, Rock CO, Wallis NG. Characterization of Streptococcus pneumoniae enoyl-(acyl-carrier protein) reductase (FabK). The Biochemical Journal. 370: 1055-62. PMID 12487627 DOI: 10.1042/Bj20021699 |
0.445 |
|
| 2003 |
Marrakchi H, Zhang YM, Rock CO. Mechanistic diversity and regulation of Type II fatty acid synthesis. Biochemical Society Transactions. 30: 1050-5. PMID 12440970 DOI: 10.1042/BST0301050 |
0.367 |
|
| 2002 |
Marrakchi H, Choi KH, Rock CO. A new mechanism for anaerobic unsaturated fatty acid formation in Streptococcus pneumoniae. The Journal of Biological Chemistry. 277: 44809-16. PMID 12237320 DOI: 10.1074/JBC.M208920200 |
0.343 |
|
| 2002 |
Rock CO, Karim MA, Zhang YM, Jackowski S. The murine pantothenate kinase (Pank1) gene encodes two differentially regulated pantothenate kinase isozymes. Gene. 291: 35-43. PMID 12095677 DOI: 10.1016/S0378-1119(02)00564-4 |
0.35 |
|
| 2002 |
Zhang YM, Marrakchi H, Rock CO. The FabR (YijC) transcription factor regulates unsaturated fatty acid biosynthesis in Escherichia coli. The Journal of Biological Chemistry. 277: 15558-65. PMID 11859088 DOI: 10.1074/JBC.M201399200 |
0.356 |
|
| 2002 |
Wong HC, Liu G, Zhang YM, Rock CO, Zheng J. The solution structure of acyl carrier protein from Mycobacterium tuberculosis. The Journal of Biological Chemistry. 277: 15874-80. PMID 11825906 DOI: 10.1074/Jbc.M112300200 |
0.422 |
|
| 2002 |
Rosenbauer F, Kallies A, Scheller M, Knobeloch K, Rock CO, Schwieger M, Stocking C, Horak I. Disabled‐2 is transcriptionally regulated by ICSBP and augments macrophage spreading and adhesion The Embo Journal. 21: 211-220. PMID 11823414 DOI: 10.1093/Emboj/21.3.211 |
0.303 |
|
| 2002 |
Heath RJ, Jackowski S, Rock CO. Chapter 3 Fatty acid and phospholipid metabolism in prokaryotes New Comprehensive Biochemistry. 36: 55-92. DOI: 10.1016/S0167-7306(02)36005-8 |
0.477 |
|
| 2002 |
Heath RJ, Jackowski S, Rock CO. Chapter 3 Fatty acid and phospholipid metabolism in prokaryotes New Comprehensive Biochemistry. 36: 55-92. |
0.304 |
|
| 2001 |
Price AC, Zhang Y, Rock CO, White SW. Structure of beta-ketoacyl-[acyl carrier protein] reductase from Escherichia coli: negative cooperativity and its structural basis. Biochemistry. 40: 12772-12781. PMID 11669613 DOI: 10.1021/Bi010737G |
0.375 |
|
| 2001 |
Heath RJ, White SW, Rock CO. Lipid biosynthesis as a target for antibacterial agents. Progress in Lipid Research. 40: 467-97. PMID 11591436 DOI: 10.1016/S0163-7827(01)00012-1 |
0.365 |
|
| 2001 |
Schujman GE, Choi K, Altabe S, Rock CO, Mendoza Dd. Response of Bacillus subtilis to cerulenin and acquisition of resistance. Journal of Bacteriology. 183: 3032-3040. PMID 11325930 DOI: 10.1128/Jb.183.10.3032-3040.2001 |
0.491 |
|
| 2001 |
Zhang YM, Rao MS, Heath RJ, Price AC, Olson AJ, Rock CO, White SW. Identification and Analysis of the Acyl Carrier Protein (ACP) Docking Site on β-Ketoacyl-ACP Synthase III Journal of Biological Chemistry. 276: 8231-8238. PMID 11078736 DOI: 10.1074/Jbc.M008042200 |
0.434 |
|
| 2001 |
Price AC, Choi KH, Heath RJ, Li Z, White SW, Rock CO. Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism. The Journal of Biological Chemistry. 276: 6551-9. PMID 11050088 DOI: 10.1074/Jbc.M007101200 |
0.425 |
|
| 2000 |
Heath RJ, Su N, Murphy CK, Rock CO. The enoyl-[acyl-carrier-protein] reductases FabI and FabL from Bacillus subtilis. Journal of Biological Chemistry. 275: 40128-40133. PMID 11007778 DOI: 10.1074/Jbc.M005611200 |
0.422 |
|
| 2000 |
Yun M, Park CG, Kim JY, Rock CO, Jackowski S, Park HW. Structural basis for the feedback regulation of Escherichia coli pantothenate kinase by coenzyme A Journal of Biological Chemistry. 275: 28093-28099. PMID 10862768 DOI: 10.1074/Jbc.M003190200 |
0.414 |
|
| 2000 |
Choi KH, Kremer L, Besra GS, Rock CO. Identification and substrate specificity of β-Ketoacyl (Acyl carrier protein) synthase III (mtFabH) from mycobacterium tuberculosis Journal of Biological Chemistry. 275: 28201-28207. PMID 10840036 DOI: 10.1074/Jbc.M003241200 |
0.442 |
|
| 2000 |
Davies C, Heath RJ, White SW, Rock CO. The 1.8 A crystal structure and active-site architecture of beta-ketoacyl-acyl carrier protein synthase III (FabH) from escherichia coli. Structure (London, England : 1993). 8: 185-95. PMID 10673437 DOI: 10.1016/S0969-2126(00)00094-0 |
0.323 |
|
| 2000 |
Heath RJ, Li J, Roland GE, Rock CO. Inhibition of the Staphylococcus aureus NADPH-dependent enoyl-acyl carrier protein reductase by triclosan and hexachlorophene. The Journal of Biological Chemistry. 275: 4654-9. PMID 10671494 DOI: 10.1074/JBC.275.7.4654 |
0.313 |
|
| 2000 |
Choi KH, Heath RJ, Rock CO. beta-ketoacyl-acyl carrier protein synthase III (FabH) is a determining factor in branched-chain fatty acid biosynthesis. Journal of Bacteriology. 182: 365-70. PMID 10629181 DOI: 10.1128/JB.182.2.365-370.2000 |
0.389 |
|
| 2000 |
Rock CO, Calder RB, Karim MA, Jackowski S. Pantothenate kinase regulation of the intracellular concentration of coenzyme A. The Journal of Biological Chemistry. 275: 1377-83. PMID 10625688 DOI: 10.1074/Jbc.275.2.1377 |
0.381 |
|
| 2000 |
Heath RJ, Rock CO. erratum: A triclosan-resistant bacterial enzyme Nature. 406: 848-848. DOI: 10.1038/35022656 |
0.31 |
|
| 1999 |
Heath RJ, Rubin JR, Holland DR, Zhang E, Snow ME, Rock CO. Mechanism of triclosan inhibition of bacterial fatty acid synthesis. The Journal of Biological Chemistry. 274: 11110-4. PMID 10196195 DOI: 10.1074/jbc.274.16.11110 |
0.325 |
|
| 1999 |
Heath RJ, Rock CO. A missense mutation accounts for the defect in the glycerol-3-phosphate acyltransferase expressed in the plsB26 mutant. Journal of Bacteriology. 181: 1944-1946. PMID 10074094 DOI: 10.1128/Jb.181.6.1944-1946.1999 |
0.334 |
|
| 1999 |
Calder RB, Williams RS, Ramaswamy G, Rock CO, Campbell E, Unkles SE, Kinghorn JR, Jackowski S. Cloning and characterization of a eukaryotic pantothenate kinase gene (panK) from Aspergillus nidulans. The Journal of Biological Chemistry. 274: 2014-20. PMID 9890959 DOI: 10.1074/Jbc.274.4.2014 |
0.384 |
|
| 1998 |
Heath RJ, Yu YT, Shapiro MA, Olson E, Rock CO. Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis. The Journal of Biological Chemistry. 273: 30316-20. PMID 9804793 DOI: 10.1074/jbc.273.46.30316 |
0.354 |
|
| 1998 |
Heath RJ, Rock CO. A Conserved Histidine Is Essential for Glycerolipid Acyltransferase Catalysis Journal of Bacteriology. 180: 1425-1430. PMID 9515909 DOI: 10.1128/Jb.180.6.1425-1430.1998 |
0.474 |
|
| 1997 |
Lykidis A, Jackson PD, Rock CO, Jackowski S. The role of CDP-diacylglycerol synthetase and phosphatidylinositol synthase activity levels in the regulation of cellular phosphatidylinositol content Journal of Biological Chemistry. 272: 33402-33409. PMID 9407135 DOI: 10.1074/Jbc.272.52.33402 |
0.324 |
|
| 1997 |
Heath RJ, Goldfine H, Rock CO. A gene (plsD) from Clostridium butyricum that functionally substitutes for the sn-glycerol-3-phosphate acyltransferase gene (plsB) of Escherichia coli. Journal of Bacteriology. 179: 7257-7263. PMID 9393688 DOI: 10.1128/Jb.179.23.7257-7263.1997 |
0.402 |
|
| 1997 |
Jackowski S, Xu XX, Rock CO. Phosphatidylcholine signaling in response to CSF-1 Molecular Reproduction and Development. 46: 24-30. PMID 8981360 DOI: 10.1002/(Sici)1098-2795(199701)46:1<24::Aid-Mrd5>3.0.Co;2-T |
0.344 |
|
| 1996 |
Heath RJ, Rock CO. Roles of the FabA and FabZ beta-hydroxyacyl-acyl carrier protein dehydratases in Escherichia coli fatty acid biosynthesis. Journal of Biological Chemistry. 271: 27795-27801. PMID 8910376 DOI: 10.1074/Jbc.271.44.27795 |
0.425 |
|
| 1996 |
Rock CO, Tsay JT, Heath R, Jackowski S. Increased unsaturated fatty acid production associated with a suppressor of the fabA6(Ts) mutation in Escherichia coli Journal of Bacteriology. 178: 5382-5387. PMID 8808925 DOI: 10.1128/Jb.178.18.5382-5387.1996 |
0.431 |
|
| 1996 |
Heath RJ, Rock CO. Inhibition Of Beta -Ketoacyl-Acyl Carrier Protein Synthase Iii (Fabh) By Acyl-Acyl Carrier Protein In Escherichia Coli Journal of Biological Chemistry. 271: 10996-11000. PMID 8631920 DOI: 10.1074/Jbc.271.18.10996 |
0.485 |
|
| 1996 |
Heath RJ, Rock CO. Regulation of fatty acid elongation and initiation by acyl-acyl carrier protein in Escherichia coli. The Journal of Biological Chemistry. 271: 1833-6. PMID 8567624 DOI: 10.1074/JBC.271.4.1833 |
0.382 |
|
| 1996 |
Rock CO, Jackowski S. Incorporation and turnover of fatty acids in Escherichia coli membrane phospholipids Advances in Lipobiology. 1: 39-59. DOI: 10.1016/S1874-5245(96)80004-8 |
0.417 |
|
| 1995 |
Heath RJ, Rock CO. Regulation of malonyl-CoA metabolism by acyl-acyl carrier protein and beta-ketoacyl-acyl carrier protein synthases in Escherichia coli. Journal of Biological Chemistry. 270: 15531-15538. PMID 7797547 DOI: 10.1074/Jbc.270.26.15531 |
0.487 |
|
| 1995 |
Xu XX, Yang W, Jackowski S, Rock CO. Cloning of a novel phosphoprotein regulated by colony-stimulating factor 1 shares a domain with the Drosophila disabled gene product Journal of Biological Chemistry. 270: 14184-14191. PMID 7775479 DOI: 10.1074/Jbc.270.23.14184 |
0.32 |
|
| 1995 |
Heath RJ, Rock CO. Enoyl-acyl carrier protein reductase (fabI) plays a determinant role in completing cycles of fatty acid elongation in Escherichia coli. The Journal of Biological Chemistry. 270: 26538-42. PMID 7592873 DOI: 10.1074/jbc.270.44.26538 |
0.331 |
|
| 1994 |
Heath RJ, Jackowski S, Rock CO. Guanosine tetraphosphate inhibition of fatty acid and phospholipid synthesis in Escherichia coli is relieved by overexpression of glycerol-3- phosphate acyltransferase (plsB) Journal of Biological Chemistry. 269: 26584-26590. PMID 7929384 |
0.376 |
|
| 1993 |
Magnuson K, Jackowski S, Rock CO, Cronan JE. Regulation of fatty acid biosynthesis in Escherichia coli Microbiological Reviews. 57: 522-542. PMID 8246839 DOI: 10.1128/mr.57.3.522-542.1993 |
0.341 |
|
| 1993 |
Magnuson K, Jackowski S, Rock CO, Cronan JE. Regulation of fatty acid biosynthesis in Escherichia coli. Microbiological Reviews. 57: 522-542. DOI: 10.1128/Mmbr.57.3.522-542.1993 |
0.376 |
|
| 1992 |
Tsay JT, Rock CO, Jackowski S. Overproduction of β-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12 Journal of Bacteriology. 174: 508-513. PMID 1729241 DOI: 10.1128/Jb.174.2.508-513.1992 |
0.426 |
|
| 1992 |
Jackowski S, Hsu L, Rock CO. 2-Acylglycerophosphoethanolamine acyltransferase/acyl-[acyl-carrier- protein] synthetase from Escherichia coli Methods in Enzymology. 209: 111-117. PMID 1495410 DOI: 10.1016/0076-6879(92)09015-U |
0.479 |
|
| 1991 |
Jackowski S, Cronan JE, Rock CO. Chapter 2 Lipid metabolism in procrayotes New Comprehensive Biochemistry. 20: 43-85. DOI: 10.1016/S0167-7306(08)60330-0 |
0.364 |
|
| 1989 |
Hsu L, Jackowski S, Rock CO. Uptake and acylation of 2-acyl-lysophospholipids by Escherichia coli Journal of Bacteriology. 171: 1203-1205. PMID 2644228 DOI: 10.1128/Jb.171.2.1203-1205.1989 |
0.408 |
|
| 1989 |
Jackowski S, Rock CO. Stimulation of phosphatidylinositol 4,5-bisphosphate phospholipase C activity by phosphatidic acid Archives of Biochemistry and Biophysics. 268: 516-524. PMID 2536532 DOI: 10.1016/0003-9861(89)90318-4 |
0.437 |
|
| 1987 |
Jackowski S, Rock CO. Acyl molecular form of acyl carrier protein associated with β-ketoacyl-acyl carrier protein synthase II (fabF) mutants Journal of Bacteriology. 169: 1469-1473. PMID 3549687 DOI: 10.1128/Jb.169.4.1469-1473.1987 |
0.388 |
|
| 1987 |
Cooper CL, Jackowski S, Rock CO. Fatty acid metabolism in sn-glycerol-3-phosphate acyltransferase (plsB) mutants. Journal of Bacteriology. 169: 605-11. PMID 3542964 DOI: 10.1128/Jb.169.2.605-611.1987 |
0.468 |
|
| 1987 |
Vallari DS, Rock CO. Isolation and characterization of temperature-sensitive pantothenate kinase (coaA) mutants of Escherichia coli Journal of Bacteriology. 169: 5795-5800. PMID 2824448 DOI: 10.1128/Jb.169.12.5795-5800.1987 |
0.324 |
|
| 1987 |
Jackowski S, Rock CO. Acetoacetyl-acyl carrier protein synthase, a potential regulator of fatty acid biosynthesis in bacteria. Journal of Biological Chemistry. 262: 7927-7931. DOI: 10.1016/s0021-9258(18)47657-0 |
0.36 |
|
| 1986 |
Jackowski S, Rock CO. Transfer of fatty acids from the 1-position of phosphatidylethanolamine to the major outer membrane lipoprotein of Escherichia coli Journal of Biological Chemistry. 261: 11328-11333. PMID 3525566 |
0.361 |
|
| 1986 |
Jackowski S, Rock CO. Consequences of reduced intracellular coenzyme A content in Escherichia coli Journal of Bacteriology. 166: 866-871. PMID 3519582 DOI: 10.1128/Jb.166.3.866-871.1986 |
0.452 |
|
| 1985 |
Rock CO, Jackowski S. Pathways for the incorporation of exogenous fatty acids into phosphatidylethanolamine in Escherichia coli Journal of Biological Chemistry. 260: 12720-12724. PMID 3900077 |
0.384 |
|
| 1985 |
Jackowski S, Edwards HH, Davis D, Rock CO. Localization of acyl carrier protein in Escherichia coli Journal of Bacteriology. 162: 5-8. PMID 3884600 DOI: 10.1128/Jb.162.1.5-8.1985 |
0.367 |
|
| 1984 |
Jackowski S, Rock CO. Metabolism of 4'-phosphopantetheine in Escherichia coli Journal of Bacteriology. 158: 115-120. PMID 6370952 DOI: 10.1128/Jb.158.1.115-120.1984 |
0.375 |
|
| 1984 |
Rock CO. Turnover of fatty acids in the 1-position of phosphatidylethanolamine in Escherichia coli. Journal of Biological Chemistry. 259: 6188-6194. DOI: 10.1016/S0021-9258(20)82124-3 |
0.318 |
|
| 1983 |
Rock CO. Environment of the aromatic chromophores of acyl carrier protein. Archives of Biochemistry and Biophysics. 225: 122-129. PMID 6614912 DOI: 10.1016/0003-9861(83)90014-0 |
0.38 |
|
| 1982 |
Rock CO, Garwin JL, Cronan JE. Preparative enzymatic synthesis of acyl-acyl carrier protein. Methods in Enzymology. 72: 397-403. PMID 7031424 DOI: 10.1016/S0076-6879(81)72029-9 |
0.443 |
|
| 1982 |
Vallari DS, Rock CO. Role of spermidine in the activity of sn-glycerol-3-phosphate acyltransferase from Escherichia coli. Archives of Biochemistry and Biophysics. 218: 402-408. PMID 6760815 DOI: 10.1016/0003-9861(82)90361-7 |
0.364 |
|
| 1982 |
Rock CO, Cronan JE. Regulation of Bacterial Membrane Lipid Synthesis Current Topics in Membranes and Transport. 17: 207-233. DOI: 10.1016/S0070-2161(08)60312-3 |
0.377 |
|
| 1981 |
Rock CO, Cronan JE. [41] Acyl carrier protein from Escherichia coli Methods in Enzymology. 71: 341-351. PMID 7024729 DOI: 10.1016/0076-6879(81)71043-7 |
0.332 |
|
| 1981 |
Rock CO, Cronan JE. [21] Acyl-acyl carrier protein synthetase from Escherichia coli Methods in Enzymology. 71: 163-168. PMID 7024728 DOI: 10.1016/0076-6879(81)71023-1 |
0.364 |
|
| 1981 |
Jackowski S, Rock CO. Regulation of coenzyme A biosynthesis Journal of Bacteriology. 148: 926-932. PMID 6796563 DOI: 10.1128/Jb.148.3.926-932.1981 |
0.376 |
|
| 1981 |
Rock C, Goelz S, Cronan J. Phospholipid synthesis in Escherichia coli. Characteristics of fatty acid transfer from acyl-acyl carrier protein to sn-glycerol 3-phosphate. Journal of Biological Chemistry. 256: 736-742. DOI: 10.1016/s0021-9258(19)70037-4 |
0.351 |
|
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