Jianfeng Cai, PhD - Publications

Chemistry University of South Florida, Tampa, FL, United States 

130 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Fu J, Liu T, Feng X, Zhou Y, Chen M, Wang W, Zhao Y, Lu C, Quan G, Cai J, Pan X, Wu C. A Perfect Pair: Stabilized Black Phosphorous Nanosheets Engineering with Antimicrobial Peptides for Robust Multi-Drug Resistant Bacteria Eradication. Advanced Healthcare Materials. e2101846. PMID 35114076 DOI: 10.1002/adhm.202101846  0.35
2022 Huang B, Zhou L, Liu R, Wang L, Xue S, Shi Y, Jeong GH, Jeong IH, Li S, Yin J, Cai J. Activation of E6AP/UBE3A-Mediated Protein Ubiquitination and Degradation Pathways by a Cyclic γ-AA Peptide. Journal of Medicinal Chemistry. PMID 35045253 DOI: 10.1021/acs.jmedchem.1c01922  0.389
2021 Abdulkadir S, Li C, Jiang W, Zhao X, Sang P, Wei L, Hu Y, Li Q, Cai J. Modulating Angiogenesis by Proteomimetics of Vascular Endothelial Growth Factor. Journal of the American Chemical Society. PMID 34968032 DOI: 10.1021/jacs.1c09571  0.635
2021 Zheng M, Lin H, Zhang W, Tang S, Liu D, Cai J. Poly(l-ornithine)-Grafted Zinc Phthalocyanines as Dual-Functional Antimicrobial Agents with Intrinsic Membrane Damage and Photothermal Ablation Capacity. Acs Infectious Diseases. PMID 34570483 DOI: 10.1021/acsinfecdis.1c00392  0.316
2021 Sang P, Zeng H, Lee C, Shi Y, Wang M, Pan C, Wei L, Huang C, Wu M, Shen W, Li X, Cai J. α/Sulfono-γ-AApeptide Hybrid Analogues of Glucagon with Enhanced Stability and Prolonged In Vivo Activity. Journal of Medicinal Chemistry. PMID 34506138 DOI: 10.1021/acs.jmedchem.1c01289  0.72
2021 Wei L, Gao R, Wang M, Wang Y, Shi Y, Gu M, Cai J. Dimeric lipo-α/sulfono-γ-AA hybrid peptides as broad-spectrum antibiotic agents. Biomaterials Science. 9: 3410-3424. PMID 33949388 DOI: 10.1039/d0bm01955k  0.545
2021 Shi Y, Sang P, Cai J. Discovery of α-helix-mimicking sulfono-γ-AApeptides as p53-MDM2 inhibitors. Future Medicinal Chemistry. 0. PMID 33906432 DOI: 10.4155/fmc-2021-0044  0.643
2021 Wang M, Feng X, Gao R, Sang P, Pan X, Wei L, Lu C, Wu C, Cai J. Modular Design of Membrane-Active Antibiotics: From Macromolecular Antimicrobials to Small Scorpionlike Peptidomimetics. Journal of Medicinal Chemistry. PMID 33789422 DOI: 10.1021/acs.jmedchem.1c00312  0.712
2020 Shi Y, Sang P, Lu J, Higbee P, Chen L, Yang L, Odom T, Daughdrill G, Chen J, Cai J. Rational Design of Right-Handed Heterogeneous Peptidomimetics as Inhibitors of Protein-Protein Interactions. Journal of Medicinal Chemistry. PMID 33140956 DOI: 10.1021/acs.jmedchem.0c01638  0.711
2020 Shi Y, Sang P, Yin G, Gao R, Liang X, Brzozowski R, Odom T, Eswara P, Zheng Y, Li X, Cai J. Aggregation-Induced Emissive and Circularly Polarized Homogeneous Sulfono-γ-AApeptide Foldamers. Advanced Optical Materials. 8. PMID 33072491 DOI: 10.1002/Adom.201902122  0.714
2020 Sang P, Shi Y, Huang B, Xue S, Odom T, Cai J. Sulfono-γ-AApeptides as Helical Mimetics: Crystal Structures and Applications. Accounts of Chemical Research. PMID 32940995 DOI: 10.1021/Acs.Accounts.0C00482  0.74
2020 Wang M, Gao R, Zheng M, Sang P, Li C, Zhang E, Li Q, Cai J. Development of Bis-Cyclic Imidazolidine-4-one Derivatives as Potent Antibacterial Agents. Journal of Medicinal Chemistry. PMID 32914977 DOI: 10.1021/Acs.Jmedchem.0C00171  0.725
2020 Pan M, Lu C, Zheng M, Zhou W, Song F, Chen W, Yao F, Liu D, Cai J. Unnatural Amino-Acid-Based Star-Shaped Poly(l-Ornithine)s as Emerging Long-Term and Biofilm-Disrupting Antimicrobial Peptides to Treat Pseudomonas aeruginosa-Infected Burn Wounds. Advanced Healthcare Materials. e2000647. PMID 32893500 DOI: 10.1002/Adhm.202000647  0.391
2020 Song R, Wang Y, Wang M, Gao R, Yang T, Yang S, Yang CG, Jin Y, Zou S, Cai J, Fan R, He Q. Design and synthesis of novel desfluoroquinolone-aminopyrimidine hybrids as potent anti-MRSA agents with low hERG activity. Bioorganic Chemistry. 103: 104176. PMID 32891858 DOI: 10.1016/J.Bioorg.2020.104176  0.405
2020 Sang P, Shi Y, Lu J, Chen L, Yang L, Borcherds W, Abdulkadir S, Li Q, Daughdrill G, Chen J, Cai J. Correction to α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions. Journal of Medicinal Chemistry. PMID 32822169 DOI: 10.1021/Acs.Jmedchem.0C01284  0.664
2020 Sang P, Shi Y, Higbee P, Wang M, Abdulkadir S, Lu J, Daughdrill GW, Chen J, Cai J. Rational Design and Synthesis of Right-Handed D-Sulfono-γ-AApeptide Helical Foldamers as Potent Inhibitors of Protein-Protein Interactions. The Journal of Organic Chemistry. PMID 32700908 DOI: 10.1021/Acs.Joc.0C00996  0.714
2020 Wang M, Gao R, Sang P, Odom T, Zheng M, Shi Y, Xu H, Cao C, Cai J. Dimeric γ-AApeptides With Potent and Selective Antibacterial Activity. Frontiers in Chemistry. 8: 441. PMID 32596202 DOI: 10.3389/Fchem.2020.00441  0.763
2020 Sang P, Zhou Z, Shi Y, Lee C, Amso Z, Huang D, Odom T, Nguyen-Tran VTB, Shen W, Cai J. The activity of sulfono-γ-AApeptide helical foldamers that mimic GLP-1. Science Advances. 6: eaaz4988. PMID 32440547 DOI: 10.1126/Sciadv.Aaz4988  0.721
2020 Wang J, Lu C, Shi Y, Feng X, Wu B, Zhou G, Quan G, Pan X, Cai J, Wu C. Structural Superiority of Guanidinium-Rich Four-Armed Copolypeptides: Role of Multiple Peptide-Membrane Interactions in Enhancing Bacterial Membrane Perturbation and Permeability. Acs Applied Materials & Interfaces. PMID 32242658 DOI: 10.1021/Acsami.0C02752  0.395
2020 Sang P, Shi Y, Lu J, Chen L, Yang L, Borcherds W, Abdulkadir S, Li Q, Daughdrill GW, Chen J, Cai J. α-Helix-Mimicking Sulfono-γ-AApeptide Inhibitors for p53-MDM2/MDMX Protein-Protein Interactions. Journal of Medicinal Chemistry. PMID 31971801 DOI: 10.1021/Acs.Jmedchem.9B00993  0.693
2020 Zhou M, Zheng M, Cai J. Small Molecules with Membrane-Active Antibacterial Activity. Acs Applied Materials & Interfaces. PMID 31944092 DOI: 10.1021/Acsami.9B20161  0.393
2020 Bolarinwa O, Li C, Khadka N, Li Q, Wang Y, Pan J, Cai J. γ-AApeptides-based Small Molecule Ligands That Disaggregate Human Islet Amyloid Polypeptide. Scientific Reports. 10: 95. PMID 31919432 DOI: 10.1038/S41598-019-56500-0  0.324
2020 Higbee PS, Daughdrill GW, Sang P, Cai J. Role of Transient Helicity and Heat Capacity in Coupled Folding and Binding of P53TAD to MDM2 and MDMX Biophysical Journal. 118: 52a. DOI: 10.1016/J.Bpj.2019.11.467  0.602
2019 Singh S, Wang M, Gao R, Teng P, Odom T, Zhang E, Xu H, Cai J. Lipidated α/Sulfono-α-AA heterogeneous peptides as antimicrobial agents for MRSA. Bioorganic & Medicinal Chemistry. 115241. PMID 31812324 DOI: 10.1016/J.Bmc.2019.115241  0.717
2019 Cai J, Su M, Shi Y, Wang M, Gao R, Wu J, Xu H, Xi C. The Activity of Small Urea-γ-AApeptides toward Gram-positive Bacteria. Chemmedchem. PMID 31677239 DOI: 10.1002/Cmdc.201900520  0.805
2019 Su M, Wang M, Hong Y, Nimmagadda A, Shen N, Shi Y, Gao R, Zhang E, Cao C, Cai J. Polymyxin derivatives as broad-spectrum antibiotic agents. Chemical Communications (Cambridge, England). PMID 31612170 DOI: 10.1039/C9Cc06908A  0.797
2019 Shi Y, Cai J. Discovery of a macrocyclic γ-AApeptide binding to lncRNA GAS5 and its therapeutic implication in Type 2 diabetes. Future Medicinal Chemistry. 11: 2233-2235. PMID 31581909 DOI: 10.4155/Fmc-2019-0148  0.38
2019 Shi Y, Yin G, Yan Z, Sang P, Wang M, Brzozowski R, Eswara P, Wojtas L, Zheng YX, Li X, Cai J. Helical Sulfono-γ-AApeptides with Aggregation-Induced Emission and Circularly Polarized Luminescence. Journal of the American Chemical Society. PMID 31335135 DOI: 10.1021/Jacs.9B05329  0.722
2019 Li C, Cai G, Song D, Gao R, Teng P, Zhou L, Ji Q, Sui H, Cai J, Li Q, Wang Y. Development of EGFR-targeted evodiamine nanoparticles for the treatment of colorectal cancer. Biomaterials Science. PMID 31328737 DOI: 10.1039/C9Bm00613C  0.599
2019 Chu W, Yang Y, Cai J, Kong H, Bai M, Fu X, Qin S, Zhang E. Synthesis and Bioactivities of New Membrane-active Agents with Aromatic Linker: High Selectivity and Broad-Spectrum Antibacterial Activity. Acs Infectious Diseases. PMID 31328496 DOI: 10.1021/Acsinfecdis.9B00078  0.449
2019 Terzyan SS, Shen T, Liu X, Huang Q, Teng P, Zhou M, Hilberg F, Cai J, Mooers BHM, Wu J. Structural basis of resistance of mutant RET protein tyrosine kinase to its inhibitors nintedanib and vandetanib. The Journal of Biological Chemistry. PMID 31118272 DOI: 10.1074/Jbc.Ra119.007682  0.617
2019 Sang P, Zhang M, Shi Y, Li C, Abdulkadir S, Li Q, Ji H, Cai J. Inhibition of β-catenin/B cell lymphoma 9 protein-protein interaction using α-helix-mimicking sulfono-γ-AApeptide inhibitors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31088961 DOI: 10.1073/Pnas.1819663116  0.694
2019 Teng P, Gray GM, Zheng M, Singh S, Li X, Wojtas L, van der Vaart A, Cai J. Orthogonal Halogen Bonding Driven 3D Supramolecular Assembly of Right-Handed Synthetic Helical Peptides. Angewandte Chemie (International Ed. in English). PMID 30957356 DOI: 10.1002/Anie.201903259  0.635
2019 Chu W, Yang Y, Qin S, Cai J, Bai M, Kong H, Zhang E. Low-toxicity amphiphilic molecules linked by an aromatic nucleus show broad-spectrum antibacterial activity and low drug resistance. Chemical Communications (Cambridge, England). PMID 30789174 DOI: 10.1039/C9Cc00857H  0.422
2019 Shi Y, Parag S, Patel R, Lui A, Murr M, Cai J, Patel NA. Stabilization of lncRNA GAS5 by a Small Molecule and Its Implications in Diabetic Adipocytes. Cell Chemical Biology. PMID 30661991 DOI: 10.1016/J.Chembiol.2018.11.012  0.388
2019 Patel N, Murr M, Lui A, Shi Y, Cai J. OR01-6 LncRNA GAS5 Directed Therapeutic Increases Insulin Receptor Expression in Adipocytes Journal of the Endocrine Society. 3. DOI: 10.1210/Js.2019-Or01-6  0.344
2019 Palumbo E, Teng P, Malaney P, Wilson J, Kearns F, Kemp MT, Tian Z, Uversky V, Allen-Gipson D, Chen Y, Woodcock HL, Cai J, Dave V. Abstract 4826: Enhancement of PTEN activity via peptidomimetics Cancer Research. 79: 4826-4826. DOI: 10.1158/1538-7445.Sabcs18-4826  0.614
2019 Liu X, Shen T, Huang Q, Peng T, Hilberg F, Cai J, Mooers BH, Wu J. Abstract 2117: Different sensitivities of four protein tyrosine kinase inhibitors towards drug-resistant RET mutations Cancer Research. 79: 2117-2117. DOI: 10.1158/1538-7445.Am2019-2117  0.342
2018 Gide M, Nimmagadda A, Su M, Wang M, Teng P, Li C, Gao R, Xu H, Li Q, Cai J. Nano-Sized Lipidated Dendrimers as Potent and Broad-Spectrum Antibacterial Agents. Macromolecular Rapid Communications. e1800622. PMID 30408252 DOI: 10.1002/Marc.201800622  0.827
2018 Bolarinwa O, Zhang M, Mulry E, Lu M, Cai J. Sulfono-γ-AA modified peptides that inhibit HIV-1 fusion. Organic & Biomolecular Chemistry. PMID 30306175 DOI: 10.1039/C8Ob02159G  0.378
2018 Singh S, Nimmagadda A, Su M, Wang M, Teng P, Cai J. Lipidated α/α-AA heterogeneous peptides as antimicrobial agents. European Journal of Medicinal Chemistry. 155: 398-405. PMID 29906686 DOI: 10.1016/J.Ejmech.2018.06.006  0.839
2018 She F, Teng P, Peguero-Tejada A, Wang M, Ma N, Odom T, Zhou M, Gjonaj E, Wojtas L, van der Vaart A, Cai J. De novo Left-Handed Synthetic Peptidomimetic Foldamers. Angewandte Chemie (International Ed. in English). PMID 29889349 DOI: 10.1002/Anie.201805184  0.608
2018 Teng P, Li C, Peng Z, Anne Marie V, Nimmagadda A, Su M, Li Y, Sun X, Cai J. Facilely accessible quinoline derivatives as potent antibacterial agents. Bioorganic & Medicinal Chemistry. PMID 29858158 DOI: 10.1016/J.Bmc.2018.05.031  0.81
2018 Li C, Teng P, Peng Z, Sang P, Sun X, Cai J. Bis-Cyclic-Guanidine as a Novel Class of Compounds Potent Against Clostridium Difficile. Chemmedchem. PMID 29768720 DOI: 10.1002/Cmdc.201800240  0.779
2018 Wang H, Qian X, Wang K, Su M, Haoyang WW, Jiang X, Brzozowski R, Wang M, Gao X, Li Y, Xu B, Eswara P, Hao XQ, Gong W, Hou JL, ... Cai J, et al. Supramolecular Kandinsky circles with high antibacterial activity. Nature Communications. 9: 1815. PMID 29739936 DOI: 10.1038/S41467-018-04247-Z  0.769
2018 Teng P, Niu Z, She F, Zhou M, Sang P, Gray GM, Verma G, Wojtas L, van der Vaart A, Ma S, Cai J. Hydrogen-Bonding-Driven 3D Supramolecular Assembly of Peptidomimetic Zipper. Journal of the American Chemical Society. PMID 29590526 DOI: 10.1021/Jacs.7B11997  0.743
2018 Niu Y, Wang M, Cao Y, Nimmagadda A, Hu J, Wu Y, Cai J, Ye XS. Rational Design of Dimeric Lysine N-Alkylamides as Potent and Broad-Spectrum Antibacterial Agents. Journal of Medicinal Chemistry. PMID 29569910 DOI: 10.1021/Acs.Jmedchem.7B01704  0.774
2018 Sun X, Ren Y, Gunawan S, Teng P, Chen Z, Lawrence HR, Cai J, Lawrence NJ, Wu J. Selective inhibition of leukemia-associated SHP2mutant by the allosteric SHP2 inhibitor SHP099. Leukemia. PMID 29568093 DOI: 10.1038/S41375-018-0020-5  0.574
2018 Sun X, Ren Y, Gunawan S, Teng P, Chen Z, Lawrence HR, Cai J, Lawrence NJ, Wu J. Abstract 4879: Mutation selectivity of the allosteric SHP2 inhibitor SHP099 Cancer Research. 78: 4879-4879. DOI: 10.1158/1538-7445.Am2018-4879  0.595
2018 Hua J, Teng P, Zou Y, Zhang C, Shen X, Cai J, Hu Y. Small antimicrobial agents encapsulated in poly(epsilon-caprolactone)-poly(ethylene glycol) nanoparticles for treatment of S. aureus-infected wounds Journal of Nanoparticle Research. 20. DOI: 10.1007/S11051-018-4369-1  0.624
2017 Shi Y, Challa S, Sang P, She F, Li C, Gray GM, Nimmagadda A, Teng P, Odom T, Wang Y, van der Vaart A, Li Q, Cai J. One-Bead-Two-Compound Thioether Bridged Macrocyclic γ-AApeptide Screening Library against EphA2. Journal of Medicinal Chemistry. 60: 9290-9298. PMID 29111705 DOI: 10.1021/Acs.Jmedchem.7B01280  0.791
2017 Nimmagadda A, Shi Y, Cai J. γ-AApeptides as a new strategy for therapeutic development. Current Medicinal Chemistry. PMID 29110596 DOI: 10.2174/0929867324666171107095913  0.572
2017 Teng P, Nimmagadda A, Su M, Hong Y, Shen N, Li C, Tsai LY, Cao J, Li Q, Cai J. Novel bis-cyclic guanidines as potent membrane-active antibacterial agents with therapeutic potential. Chemical Communications (Cambridge, England). PMID 29052670 DOI: 10.1039/C7Cc07285F  0.822
2017 Su M, Xia D, Teng P, Nimmagadda A, Zhang C, Odom T, Cao A, Hu Y, Cai J. Membrane-Active Hydantoin Derivatives as Antibiotic Agents. Journal of Medicinal Chemistry. PMID 28984451 DOI: 10.1021/Acs.Jmedchem.7B00847  0.825
2017 Teng P, Ma N, Cerrato DC, She F, Odom T, Wang X, Ming LJ, van der Vaart A, Wojtas L, Xu H, Cai J. Right-Handed Helical Foldamers Consisting of De Novo d-AApeptides. Journal of the American Chemical Society. 139: 7363-7369. PMID 28480699 DOI: 10.1021/Jacs.7B03007  0.641
2017 Pan J, Sahoo PK, Dalzini A, Hayati Z, Aryal CM, Teng P, Cai J, Gutierrez HR, Song L. Membrane Disruption Mechanism of a Prion Peptide (106-126) Investigated by Atomic Force Microscopy, Raman and Electron Paramagnetic Resonance Spectroscopy. The Journal of Physical Chemistry. B. PMID 28459565 DOI: 10.1021/Acs.Jpcb.7B02772  0.625
2017 Khadka NK, Teng P, Cai J, Pan J. Modulation of Lipid Membrane Structural and Mechanical Properties by a Peptidomimetic Derived from Reduced Amide Scaffold. Biochimica Et Biophysica Acta. PMID 28132901 DOI: 10.1016/J.Bbamem.2017.01.026  0.617
2017 Nimmagadda A, Liu X, Teng P, Su M, Li Y, Qiao Q, Khadka NK, Sun X, Pan J, Xu H, Li Q, Cai J. Polycarbonates with Potent and Selective Antimicrobial Activity toward Gram-Positive Bacteria. Biomacromolecules. 18: 87-95. PMID 28064500 DOI: 10.1021/Acs.Biomac.6B01385  0.821
2016 Lin X, Bai G, Sutherland K, Costanza F, Breitenkamp K, Sill K, Cai J, Cao C. Polymer-Encapsulated Aβ Peptide Fragments as an Oligomeric-Specific Vaccine for Alzheimer's Disease. Journal of Biomedical Nanotechnology. 12: 1421-30. PMID 29336537 DOI: 10.1166/Jbn.2016.2256  0.311
2016 Bolarinwa O, Nimmagadda A, Su M, Cai J. Structure and Function of AApeptides. Biochemistry. PMID 28029249 DOI: 10.1021/Acs.Biochem.6B01132  0.792
2016 Sang P, Shi Y, Teng P, Cao A, Xu H, Li Q, Cai J. Antimicrobial AA Peptides. Current Topics in Medicinal Chemistry. PMID 27758686  0.81
2016 Teng P, Huo D, Nimmagadda A, Wu J, She F, Su M, Lin X, Yan J, Cao A, Xi C, Hu Y, Cai J. Small antimicrobial agents based on acylated reduced amide scaffold. Journal of Medicinal Chemistry. PMID 27526720 DOI: 10.1021/Acs.Jmedchem.6B00640  0.83
2016 She F, Oyesiku O, Zhou P, Zhuang S, Koenig DW, Cai J. The development of antimicrobial γ-AApeptides. Future Medicinal Chemistry. PMID 27284624 DOI: 10.4155/Fmc-2016-0034  0.505
2016 Kaur P, Li Y, Cai J, Song L. Selective Membrane Disruption Mechanism of an Antibacterial γ-AApeptide Defined by EPR Spectroscopy. Biophysical Journal. 110: 1789-1799. PMID 27119639 DOI: 10.1016/J.Bpj.2016.02.038  0.361
2016 She F, Nimmagadda A, Teng P, Su M, Zuo X, Cai J. Helical 1:1 α/sulfono-γ-AA heterogeneous peptides with antibacterial activity. Biomacromolecules. PMID 27030636 DOI: 10.1021/Acs.Biomac.6B00286  0.847
2016 Teng P, Shi Y, Sang P, Cai J. γ-AApeptides as a New Class of Peptidomimetics. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 26945679 DOI: 10.1002/Chem.201504936  0.816
2016 Shi Y, Teng P, Sang P, She F, Wei L, Cai J. γ-AApeptides: Design, Structure, and Applications. Accounts of Chemical Research. PMID 26900964 DOI: 10.1021/Acs.Accounts.5B00492  0.822
2015 Zhao YZ, Chen LJ, Lin Q, Cai J, Yu WZ, Zhao YP, Xu CY, Mao KL, Tian FR, Li WF, Wong HL, Lu CT. Using FUS induced BBB/BTB-opening technique combined with Doxorubicin liposomes to improve glioma-targeted inhibition. Oncotarget. PMID 26573227 DOI: 10.18632/oncotarget.5144  0.319
2015 Wu H, Jiang J, Xu H, Li Q, Cai J. RGD mimetics γ-AApeptides and methods of use (US 20,140,004,039 A1): a patent evaluation. Expert Opinion On Therapeutic Patents. 1-7. PMID 26560186 DOI: 10.1517/13543776.2016.1111337  0.696
2015 Zhao GX, Xu LH, Pan H, Lin QR, Huang MY, Cai JY, Ouyang DY, He XH. The BH3-mimetic gossypol and noncytotoxic doses of valproic acid induce apoptosis by suppressing cyclin-A2/Akt/FOXO3a signaling. Oncotarget. PMID 26517515 DOI: 10.18632/oncotarget.5731  0.313
2015 Huang Y, Huang J, Cai J, Lin W, Lin Q, Wu F, Luo J. Carboxymethyl chitosan/clay nanocomposites and their copper complexes: Fabrication and property. Carbohydrate Polymers. 134: 390-7. PMID 26428139 DOI: 10.1016/j.carbpol.2015.07.089  0.339
2015 Zhao H, Guo Y, Li S, Han R, Ying J, Zhu H, Wang Y, Yin L, Han Y, Sun L, Wang Z, Lin Q, Bi X, Jiao Y, Jia H, ... ... Cai J, et al. A novel anti-cancer agent Icaritin suppresses hepatocellular carcinoma initiation and malignant growth through the IL-6/Jak2/Stat3 pathway. Oncotarget. PMID 26376676 DOI: 10.18632/Oncotarget.5578  0.36
2015 Shi X, Yang S, Zhang G, Song Y, Su D, Liu Y, Guo F, Shan L, Cai J. The different metabolism of morusin in various species and its potent inhibition against UDP-glucuronosyltransferase (UGT) and cytochrome p450 (CYP450) enzymes. Xenobiotica; the Fate of Foreign Compounds in Biological Systems. 1-10. PMID 26372370 DOI: 10.3109/00498254.2015.1086839  0.327
2015 Cai J, Wang Y, Schwarz S, Lv H, Li Y, Liao K, Yu S, Zhao K, Gu D, Wang X, Zhang R, Shen J. Enterococcal isolates carrying the novel oxazolidinone resistance gene optrA from hospitals in Zhejiang, Guangdong, and Henan, China, 2010-2014. Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases. PMID 26319902 DOI: 10.1016/j.cmi.2015.08.007  0.456
2015 Sargsyan A, Cai J, Fandino LB, Labasky ME, Forostyan T, Colosimo LK, Thompson SJ, Graham TE. Rapid parallel measurements of macroautophagy and mitophagy in mammalian cells using a single fluorescent biosensor. Scientific Reports. 5: 12397. PMID 26215030 DOI: 10.1038/srep12397  0.431
2015 Wu H, Qiao Q, Teng P, Hu Y, Antoniadis D, Zuo X, Cai J. New Class of Heterogeneous Helical Peptidomimetics. Organic Letters. 17: 3524-7. PMID 26153619 DOI: 10.1021/Acs.Orglett.5B01608  0.793
2015 Li Y, Wu H, Teng P, Bai G, Lin X, Zuo X, Cao C, Cai J. Helical Antimicrobial Sulfono-γ-AApeptides. Journal of Medicinal Chemistry. 58: 4802-11. PMID 26020456 DOI: 10.1021/Acs.Jmedchem.5B00537  0.818
2015 Padhee S, Li Y, Cai J. Activity of lipo-cyclic γ-AApeptides against biofilms of Staphylococcus epidermidis and Pseudomonas aeruginosa. Bioorganic & Medicinal Chemistry Letters. 25: 2565-9. PMID 25977094 DOI: 10.1016/J.Bmcl.2015.04.039  0.372
2015 Hu YY, Gu DX, Cai JC, Zhou HW, Zhang R. Emergence of KPC-2-producing Pseudomonas aeruginosa sequence type 463 isolates in Hangzhou, China. Antimicrobial Agents and Chemotherapy. 59: 2914-7. PMID 25691651 DOI: 10.1128/AAC.04903-14  0.471
2015 Wu H, Qiao Q, Hu Y, Teng P, Gao W, Zuo X, Wojtas L, Larsen RW, Ma S, Cai J. Sulfono-γ-AApeptides as a new class of nonnatural helical foldamer. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 2501-7. PMID 25504756 DOI: 10.1002/Chem.201406112  0.797
2015 Wu H, She F, Gao W, Prince A, Li Y, Wei L, Mercer A, Wojtas L, Ma S, Cai J. The synthesis of head-to-tail cyclic sulfono-γ-AApeptides. Organic & Biomolecular Chemistry. 13: 672-6. PMID 25420701 DOI: 10.1039/C4Ob02232G  0.663
2015 Teng P, Wu H, Lin L, Cai J. Antimicrobial γ-AApeptides (WO2013112548): a patent evaluation. Expert Opinion On Therapeutic Patents. 25: 111-8. PMID 25331592 DOI: 10.1517/13543776.2014.973855  0.821
2015 Kaur P, Li Y, Cai J, Song L. Membrane Interaction of an Anti-Bacterial AApeptide Defined by EPR Spectroscopy Biophysical Journal. 108: 550a. DOI: 10.1016/J.Bpj.2014.11.3019  0.38
2014 Wang Y, Costanza F, Wu H, Song D, Cai J, Li Q. PEG-poly(amino acid)s-encapsulated tanshinone IIA as potential therapeutics for the treatment of hepatoma. Journal of Materials Chemistry. B. 2: 3115-3122. PMID 32261687 DOI: 10.1039/C4Tb00041B  0.676
2014 Wang Y, Song D, Costanza F, Ji G, Fan Z, Cai J, Li Q. Targeted delivery of tanshinone IIA-conjugated mPEG-PLGA-PLL-cRGD nanoparticles to hepatocellular carcinoma. Journal of Biomedical Nanotechnology. 10: 3244-52. PMID 26000384 DOI: 10.1166/Jbn.2014.1982  0.302
2014 Hu Y, Cheng N, Wu H, Kang S, Ye RD, Cai J. Design, synthesis and characterization of fMLF-mimicking AApeptides. Chembiochem : a European Journal of Chemical Biology. 15: 2420-6. PMID 25224835 DOI: 10.1002/Cbic.201402396  0.77
2014 Li Y, Smith C, Wu H, Teng P, Shi Y, Padhee S, Jones T, Nguyen AM, Cao C, Yin H, Cai J. Short antimicrobial lipo-α/γ-AA hybrid peptides. Chembiochem : a European Journal of Chemical Biology. 15: 2275-80. PMID 25169879 DOI: 10.1002/Cbic.201402264  0.835
2014 Teng P, Zhang X, Wu H, Qiao Q, Sebti SM, Cai J. Identification of novel inhibitors that disrupt STAT3-DNA interaction from a γ-AApeptide OBOC combinatorial library. Chemical Communications (Cambridge, England). 50: 8739-42. PMID 24964402 DOI: 10.1039/C4Cc03909B  0.757
2014 Padhee S, Smith C, Wu H, Li Y, Manoj N, Qiao Q, Khan Z, Cao C, Yin H, Cai J. The development of antimicrobial a-AApeptides that suppress proinflammatory immune responses. Chembiochem : a European Journal of Chemical Biology. 15: 688-94. PMID 24677440 DOI: 10.1002/Cbic.201300709  0.783
2014 Gao WY, Chen Y, Niu Y, Williams K, Cash L, Perez PJ, Wojtas L, Cai J, Chen YS, Ma S. Crystal engineering of an nbo topology metal-organic framework for chemical fixation of CO2 under ambient conditions. Angewandte Chemie (International Ed. in English). 53: 2615-9. PMID 24497432 DOI: 10.1002/Anie.201309778  0.685
2014 Wu H, Li Y, Bai G, Niu Y, Qiao Q, Tipton JD, Cao C, Cai J. γ-AApeptide-based small-molecule ligands that inhibit Aβ aggregation. Chemical Communications (Cambridge, England). 50: 5206-8. PMID 24158240 DOI: 10.1039/C3Cc46685J  0.792
2014 Li Y, Smith C, Wu H, Padhee S, Manoj N, Cardiello J, Qiao Q, Cao C, Yin H, Cai J. Lipidated cyclic γ-AApeptides display both antimicrobial and anti-inflammatory activity. Acs Chemical Biology. 9: 211-7. PMID 24144063 DOI: 10.1021/Cb4006613  0.778
2014 Costanza F, Padhee S, Wu H, Wang Y, Revenis J, Cao C, Li Q, Cai J. Investigation of antimicrobial PEG-poly(amino acid)s Rsc Advances. 4: 2089-2095. DOI: 10.1039/C3Ra44324H  0.711
2014 Wu H, Cai J. Engineering aapeptides for translational medicine Engineering in Translational Medicine. 2147483647: 983-999. DOI: 10.1007/978-1-4471-4372-7_35  0.583
2014 Wu H, Teng P, Cai J. Rapid access to multiple classes of peptidomimetics from common γ-AApeptide building blocks European Journal of Organic Chemistry. 2014: 1760-1765. DOI: 10.1002/Ejoc.201301841  0.772
2014 Teng P, Wu H, Cai J. Peptidomimetics as Antimicrobial Agents Novel Antimicrobial Agents and Strategies. 91-108. DOI: 10.1002/9783527676132.ch6  0.755
2013 Wang RE, Zhang Y, Tian L, Cai W, Cai J. Antibody-based imaging of HER-2: Moving into the clinic Current Molecular Medicine. 13: 1523-1537. PMID 24206138 DOI: 10.2174/1566524013666131111120951  0.629
2013 Niu Y, Hu Y, Wu H, Cai J. Synthesis of AApeptides. Methods in Molecular Biology (Clifton, N.J.). 1081: 35-46. PMID 24014432 DOI: 10.1007/978-1-62703-652-8_3  0.826
2013 Wu H, Teng P, Niu Y, Li Q, Cai J. Polymyxin derivatives: a patent evaluation (WO2012168820). Expert Opinion On Therapeutic Patents. 23: 1075-81. PMID 23806121 DOI: 10.1517/13543776.2013.814641  0.79
2013 Li Y, Wu H, Niu Y, Hu Y, Li Q, Cao C, Cai J. Development of RNA aptamer-based therapeutic agents. Current Medicinal Chemistry. 20: 3655-63. PMID 23745560 DOI: 10.2174/0929867311320290011  0.671
2013 Niu Y, Wu H, Li Y, Hu Y, Padhee S, Li Q, Cao C, Cai J. AApeptides as a new class of antimicrobial agents. Organic & Biomolecular Chemistry. 11: 4283-90. PMID 23722277 DOI: 10.1039/C3Ob40444G  0.839
2013 Bai G, Wu H, Li Y, Niu Y, Qiao Q, Lin X, Cai J, Cao C. P2-060: Anti-aggregation effect of AA-peptide on beta-amyloid peptides in Alzheimer's disease Alzheimer's & Dementia. 9: P364-P365. DOI: 10.1016/J.Jalz.2013.05.703  0.789
2012 Hu Y, Amin MN, Padhee S, Wang RE, Qiao Q, Bai G, Li Y, Mathew A, Cao C, Cai J. Lipidated peptidomimetics with improved antimicrobial activity. Acs Medicinal Chemistry Letters. 3: 683-6. PMID 24900530 DOI: 10.1021/Ml3001215  0.781
2012 Niu Y, Wang RE, Wu H, Cai J. Recent development of small antimicrobial peptidomimetics. Future Medicinal Chemistry. 4: 1853-62. PMID 23043481 DOI: 10.4155/Fmc.12.111  0.829
2012 Yang Y, Niu Y, Hong H, Wu H, Zhang Y, Engle JW, Barnhart TE, Cai J, Cai W. Radiolabeled γ-AApeptides: a new class of tracers for positron emission tomography. Chemical Communications (Cambridge, England). 48: 7850-2. PMID 22785080 DOI: 10.1039/C2Cc33620K  0.794
2012 Wu H, Amin MN, Niu Y, Qiao Q, Harfouch N, Nimer A, Cai J. Solid-phase synthesis of γ-AApeptides using a submonomeric approach. Organic Letters. 14: 3446-9. PMID 22731678 DOI: 10.1021/Ol301406A  0.782
2012 Niu Y, Padhee S, Wu H, Bai G, Qiao Q, Hu Y, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. Lipo-γ-AApeptides as a new class of potent and broad-spectrum antimicrobial agents. Journal of Medicinal Chemistry. 55: 4003-9. PMID 22475244 DOI: 10.1021/Jm300274P  0.836
2012 Niu Y, Bai G, Wu H, Wang RE, Qiao Q, Padhee S, Buzzeo R, Cao C, Cai J. Cellular translocation of a γ-AApeptide mimetic of Tat peptide. Molecular Pharmaceutics. 9: 1529-34. PMID 22413929 DOI: 10.1021/Mp300070W  0.808
2012 Bai G, Padhee S, Niu Y, Wang RE, Qiao Q, Buzzeo R, Cao C, Cai J. Cellular uptake of an α-AApeptide. Organic & Biomolecular Chemistry. 10: 1149-53. PMID 22193209 DOI: 10.1039/C2Ob06679C  0.814
2012 Wang RE, Costanza F, Niu Y, Wu H, Hu Y, Hang W, Sun Y, Cai J. Development of self-immolative dendrimers for drug delivery and sensing. Journal of Controlled Release : Official Journal of the Controlled Release Society. 159: 154-63. PMID 22155555 DOI: 10.1016/J.Jconrel.2011.11.032  0.785
2012 Wang RE, Pandita RK, Cai J, Hunt CR, Taylor JS. Inhibition of heat shock transcription factor binding by a linear polyamide binding in an unusual 1:1 mode. Chembiochem : a European Journal of Chemical Biology. 13: 97-104. PMID 22134972 DOI: 10.1002/Cbic.201100524  0.618
2012 Wang RE, Niu Y, Wu H, Hu Y, Cai J. Development of NGR-based anti-cancer agents for targeted therapeutics and imaging. Anti-Cancer Agents in Medicinal Chemistry. 12: 76-86. PMID 22023047 DOI: 10.2174/187152012798764714  0.79
2012 Wu H, Niu Y, Padhee S, Wang RE, Li Y, Qiao Q, Bai G, Cao C, Cai J. Design and synthesis of unprecedented cyclic γ-AApeptides for antimicrobial development Chemical Science. 3: 2570-2575. DOI: 10.1039/C2Sc20428B  0.834
2012 Gao WY, Niu Y, Chen Y, Wojtas L, Cai J, Chen YS, Ma S. Porous metal-organic framework based on a macrocyclic tetracarboxylate ligand exhibiting selective CO 2 uptake Crystengcomm. 14: 6115-6117. DOI: 10.1039/C2Ce25484K  0.695
2012 Niu Y, Wu H, Huang R, Qiao Q, Costanza F, Wang XS, Hu Y, Amin MN, Nguyen AM, Zhang J, Haller E, Ma S, Li X, Cai J. Nanorods formed from a new class of peptidomimetics Macromolecules. 45: 7350-7355. DOI: 10.1021/Ma3015992  0.808
2011 Wang RE, Niu Y, Wu H, Amin MN, Cai J. Development of NGR peptide-based agents for tumor imaging. American Journal of Nuclear Medicine and Molecular Imaging. 1: 36-46. PMID 23133793  0.789
2011 Niu Y, Padhee S, Wu H, Bai G, Harrington L, Burda WN, Shaw LN, Cao C, Cai J. Identification of γ-AApeptides with potent and broad-spectrum antimicrobial activity. Chemical Communications (Cambridge, England). 47: 12197-9. PMID 21963627 DOI: 10.1039/C1Cc14476F  0.818
2011 Wang RE, Wu H, Niu Y, Cai J. Improving the stability of aptamers by chemical modification Current Medicinal Chemistry. 18: 4126-4138. PMID 21838692 DOI: 10.2174/092986711797189565  0.794
2011 Wang RE, Zhang Y, Cai J, Cai W, Gao T. Aptamer-based fluorescent biosensors Current Medicinal Chemistry. 18: 4175-4184. PMID 21838688 DOI: 10.2174/092986711797189637  0.63
2011 Niu Y, Jones AJ, Wu H, Varani G, Cai J. γ-AApeptides bind to RNA by mimicking RNA-binding proteins. Organic & Biomolecular Chemistry. 9: 6604-9. PMID 21826330 DOI: 10.1039/C1Ob05738C  0.769
2011 Padhee S, Hu Y, Niu Y, Bai G, Wu H, Costanza F, West L, Harrington L, Shaw LN, Cao C, Cai J. Non-hemolytic α-AApeptides as antimicrobial peptidomimetics. Chemical Communications (Cambridge, England). 47: 9729-31. PMID 21779608 DOI: 10.1039/C1Cc13684D  0.827
2011 Hu Y, Li X, Sebti SM, Chen J, Cai J. Design and synthesis of AApeptides: a new class of peptide mimics. Bioorganic & Medicinal Chemistry Letters. 21: 1469-71. PMID 21292484 DOI: 10.1016/J.Bmcl.2011.01.005  0.688
2011 Niu Y, Hu Y, Li X, Chen J, Cai J. γ-AApeptides: Design, synthesis and evaluation New Journal of Chemistry. 35: 542-545. DOI: 10.1039/C0Nj00943A  0.827
2010 Saha S, Cai J, Eiler D, Hamilton AD. Programing the formation of DNA and PNA quadruplexes by pi-pi-stacking interactions. Chemical Communications (Cambridge, England). 46: 1685-7. PMID 20177616 DOI: 10.1039/B915955J  0.414
2010 Cai J, Niedzwiedzki DM, Frank HA, Hamilton AD. Ultrafast energy transfer within pyropheophorbide-a tethered to self-assembling DNA quadruplex. Chemical Communications (Cambridge, England). 46: 544-6. PMID 20062856 DOI: 10.1039/B908435E  0.406
2010 Cheng Y, Tsou LK, Cai J, Aya T, Dutschman GE, Gullen EA, Grill SP, Chen AP, Lindenbach BD, Hamilton AD, Cheng YC. A novel class of meso-tetrakis-porphyrin derivatives exhibits potent activities against hepatitis C virus genotype 1b replicons in vitro. Antimicrobial Agents and Chemotherapy. 54: 197-206. PMID 19901090 DOI: 10.1128/Aac.01206-09  0.735
2009 Cai J, Shapiro EM, Hamilton AD. Self-assembling DNA quadruplex conjugated to MRI contrast agents. Bioconjugate Chemistry. 20: 205-8. PMID 19125646 DOI: 10.1021/Bc8004182  0.438
2009 Cai J, Rosenzweig BA, Hamilton AD. Inhibition of chymotrypsin by a self-assembled DNA quadruplex functionalized with cyclic peptide binding fragments. Chemistry (Weinheim An Der Bergstrasse, Germany). 15: 328-32. PMID 19053105 DOI: 10.1002/Chem.200801637  0.708
2005 Cai J, Li X, Taylor JS. Improved nucleic acid triggered probe activation through the use of a 5-thiomethyluracil peptide nucleic acid building block. Organic Letters. 7: 751-4. PMID 15727432 DOI: 10.1021/Ol0478382  0.337
2004 Cai J, Li X, Yue X, Taylor JS. Nucleic acid-triggered fluorescent probe activation by the Staudinger reaction. Journal of the American Chemical Society. 126: 16324-5. PMID 15600325 DOI: 10.1021/Ja0452626  0.499
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