Scott D. Emr - Publications

1983-1991 California Institute of Technology, Pasadena, CA 
 1991-2007 University of California, San Diego School of Medicine, San Diego, CA, United States 
 2007- Molecular Biology and Genetics Cornell University, Ithaca, NY, United States 
biogenesis of organelles

244 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Suzuki SW, Emr SD. Immunoisolation of Endosomal Recycling Vesicles from . Bio-Protocol. 12: e4403. PMID 35800464 DOI: 10.21769/BioProtoc.4403  0.329
2022 Zhu L, Zhang Q, Cordeiro CD, Banjade S, Sardana R, Mao Y, Emr SD. Adaptor linked K63 di-Ubiquitin activates Nedd4/Rsp5 E3 ligase. Elife. 11. PMID 35770973 DOI: 10.7554/eLife.77424  0.382
2022 Banjade S, Zhu L, Jorgensen JR, Suzuki SW, Emr SD. Recruitment and organization of ESCRT-0 and ubiquitinated cargo via condensation. Science Advances. 8: eabm5149. PMID 35363519 DOI: 10.1126/sciadv.abm5149  0.401
2022 Neuman SD, Jorgensen JR, Cavanagh AT, Smyth JT, Selegue JE, Emr SD, Bashirullah A. The Hob proteins are novel and conserved lipid-binding proteins at ER-PM contact sites. Journal of Cell Science. 135. PMID 34415038 DOI: 10.1242/jcs.259086  0.381
2021 Sardana R, Highland CM, Straight BE, Chavez CF, Fromme JC, Emr SD. Golgi membrane protein Erd1 Is essential for recycling a subset of Golgi glycosyltransferases. Elife. 10. PMID 34821548 DOI: 10.7554/eLife.70774  0.345
2021 Suzuki SW, Oishi A, Nikulin N, Jorgensen JR, Baile MG, Emr SD. A PX-BAR protein Mvp1/SNX8 and a dynamin-like GTPase Vps1 drive endosomal recycling. Elife. 10. PMID 34524084 DOI: 10.7554/eLife.69883  0.839
2021 Sardana R, Emr SD. Membrane Protein Quality Control Mechanisms in the Endo-Lysosome System. Trends in Cell Biology. PMID 33414051 DOI: 10.1016/j.tcb.2020.11.011  0.368
2020 Zhu L, Sardana R, Jin DK, Emr SD. Calcineurin-dependent regulation of endocytosis by a plasma membrane ubiquitin ligase adaptor, Rcr1. The Journal of Cell Biology. 219. PMID 32421152 DOI: 10.1083/Jcb.201909158  0.54
2020 Jorgensen JR, Tei R, Baskin JM, Michel AH, Kornmann B, Emr SD. ESCRT-III and ER-PM contacts maintain lipid homeostasis. Molecular Biology of the Cell. mbcE20010061. PMID 32267208 DOI: 10.1091/Mbc.E20-01-0061  0.409
2019 Baile MG, Guiney EL, Sanford EJ, MacGurn JA, Smolka MB, Emr SD. Activity of a ubiquitin ligase adaptor is regulated by disordered insertions in its arrestin domain. Molecular Biology of the Cell. mbcE19080451. PMID 31618110 DOI: 10.1091/Mbc.E19-08-0451  0.825
2019 Suzuki SW, Chuang YS, Li M, Seaman MNJ, Emr SD. A bipartite sorting signal ensures specificity of retromer complex in membrane protein recycling. The Journal of Cell Biology. PMID 31337624 DOI: 10.1083/Jcb.201901019  0.544
2019 Banjade S, Tang S, Emr SD. Genetic and Biochemical Analyses of Yeast ESCRT. Methods in Molecular Biology (Clifton, N.J.). 1998: 105-116. PMID 31250297 DOI: 10.1007/978-1-4939-9492-2_8  0.545
2019 Banjade S, Tang S, Shah YH, Emr SD. Electrostatic lateral interactions drive ESCRT-III heteropolymer assembly. Elife. 8. PMID 31246173 DOI: 10.7554/Elife.46207  0.314
2019 Guiney EL, Zhu L, Sardana R, Emr SD, Baile MG. Methods for studying the regulation of membrane traffic by ubiquitin and the ESCRT pathway. Methods in Enzymology. 619: 269-291. PMID 30910024 DOI: 10.1016/Bs.Mie.2018.12.041  0.843
2018 Sardana R, Zhu L, Emr SD. Rsp5 Ubiquitin ligase-mediated quality control system clears membrane proteins mistargeted to the vacuole membrane. The Journal of Cell Biology. PMID 30361468 DOI: 10.1083/Jcb.201806094  0.539
2018 Suzuki SW, Emr SD. Retrograde trafficking from the vacuole/lysosome membrane. Autophagy. PMID 29995558 DOI: 10.1080/15548627.2018.1496719  0.514
2018 Suzuki SW, Emr SD. Membrane protein recycling from the vacuole/lysosome membrane. The Journal of Cell Biology. PMID 29511122 DOI: 10.1083/Jcb.201709162  0.551
2017 Zhu L, Jorgensen JR, Li M, Chuang YS, Emr SD. ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins. Elife. 6. PMID 28661397 DOI: 10.7554/Elife.26403  0.582
2017 Ho HC, MacGurn JA, Emr SD. Deubiquitinating enzymes Ubp2 and Ubp15 regulate endocytosis by limiting ubiquitination and degradation of ARTs. Molecular Biology of the Cell. PMID 28298493 DOI: 10.1091/Mbc.E17-01-0008  0.513
2017 Zhu L, Jorgensen JR, Li M, Chuang Y, Emr SD. Author response: ESCRTs function directly on the lysosome membrane to downregulate ubiquitinated lysosomal membrane proteins Elife. DOI: 10.7554/Elife.26403.023  0.486
2016 Guiney EL, Klecker T, Emr SD. Identification of the endocytic sorting signal recognized by the Art1-Rsp5 ubiquitin ligase complex. Molecular Biology of the Cell. PMID 27798240 DOI: 10.1091/Mbc.E16-08-0570  0.848
2016 Tang S, Buchkovich NJ, Henne WM, Banjade S, Kim YJ, Emr SD. ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis. Elife. 5. PMID 27074665 DOI: 10.7554/Elife.15507  0.713
2016 Omnus DJ, Manford AG, Bader JM, Emr SD, Stefan CJ. PI Kinase Signaling Controls ER-PM Crosstalk. Molecular Biology of the Cell. PMID 26864629 DOI: 10.1091/Mbc.E16-01-0002  0.422
2016 Tang S, Buchkovich NJ, Henne WM, Banjade S, Kim YJ, Emr SD. Author response: ESCRT-III activation by parallel action of ESCRT-I/II and ESCRT-0/Bro1 during MVB biogenesis Elife. DOI: 10.7554/Elife.15507.026  0.61
2015 Tang S, Henne WM, Borbat PP, Buchkovich NJ, Freed JH, Mao Y, Fromme JC, Emr SD. Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments. Elife. 4. PMID 26670543 DOI: 10.7554/Elife.12548  0.742
2015 Li M, Koshi T, Emr SD. Membrane-anchored ubiquitin ligase complex is required for the turnover of lysosomal membrane proteins. The Journal of Cell Biology. 211: 639-52. PMID 26527740 DOI: 10.1083/Jcb.201505062  0.56
2015 Henne WM, Zhu L, Balogi Z, Stefan C, Pleiss JA, Emr SD. Mdm1/Snx13 is a novel ER-endolysosomal interorganelle tethering protein. The Journal of Cell Biology. 210: 541-51. PMID 26283797 DOI: 10.1083/Jcb.201503088  0.718
2015 Henne WM, Liou J, Emr SD. Molecular mechanisms of inter-organelle ER-PM contact sites. Current Opinion in Cell Biology. 35: 123-130. PMID 26025028 DOI: 10.1016/J.Ceb.2015.05.001  0.706
2015 Li M, Rong Y, Chuang YS, Peng D, Emr SD. Ubiquitin-dependent lysosomal membrane protein sorting and degradation. Molecular Cell. 57: 467-78. PMID 25620559 DOI: 10.1016/J.Molcel.2014.12.012  0.545
2015 Tang S, Henne WM, Borbat PP, Buchkovich NJ, Freed JH, Mao Y, Fromme JC, Emr SD. Author response: Structural basis for activation, assembly and membrane binding of ESCRT-III Snf7 filaments Elife. DOI: 10.7554/Elife.12548.037  0.674
2013 Mellman I, Emr SD. A Nobel Prize for membrane traffic: vesicles find their journey's end. The Journal of Cell Biology. 203: 559-61. PMID 24215073 DOI: 10.1083/Jcb.201310134  0.362
2013 Buchkovich NJ, Henne WM, Tang S, Emr SD. Essential N-terminal insertion motif anchors the ESCRT-III filament during MVB vesicle formation. Developmental Cell. 27: 201-14. PMID 24139821 DOI: 10.1016/J.Devcel.2013.09.009  0.722
2013 Henne WM, Stenmark H, Emr SD. Molecular mechanisms of the membrane sculpting ESCRT pathway. Cold Spring Harbor Perspectives in Biology. 5. PMID 24003212 DOI: 10.1101/Cshperspect.A016766  0.713
2013 Han BK, Emr SD. The phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2)-dependent Tup1 conversion (PIPTC) regulates metabolic reprogramming from glycolysis to gluconeogenesis. The Journal of Biological Chemistry. 288: 20633-45. PMID 23733183 DOI: 10.1074/Jbc.M113.452813  0.305
2013 Zhao Y, Macgurn JA, Liu M, Emr S. The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress. Elife. 2: e00459. PMID 23599894 DOI: 10.7554/Elife.00459  0.605
2013 Stefan CJ, Manford AG, Emr SD. ER-PM connections: sites of information transfer and inter-organelle communication. Current Opinion in Cell Biology. 25: 434-42. PMID 23522446 DOI: 10.1016/J.Ceb.2013.02.020  0.409
2013 Zhao Y, MacGurn JA, Liu M, Emr S. Author response: The ART-Rsp5 ubiquitin ligase network comprises a plasma membrane quality control system that protects yeast cells from proteotoxic stress Elife. DOI: 10.7554/Elife.00459.029  0.536
2012 Manford AG, Stefan CJ, Yuan HL, Macgurn JA, Emr SD. ER-to-plasma membrane tethering proteins regulate cell signaling and ER morphology. Developmental Cell. 23: 1129-40. PMID 23237950 DOI: 10.1016/J.Devcel.2012.11.004  0.494
2012 Henne WM, Buchkovich NJ, Zhao Y, Emr SD. The endosomal sorting complex ESCRT-II mediates the assembly and architecture of ESCRT-III helices. Cell. 151: 356-71. PMID 23063125 DOI: 10.1016/J.Cell.2012.08.039  0.745
2012 Ling Y, Stefan CJ, Macgurn JA, Audhya A, Emr SD. The dual PH domain protein Opy1 functions as a sensor and modulator of PtdIns(4,5)P₂ synthesis. The Embo Journal. 31: 2882-94. PMID 22562153 DOI: 10.1038/Emboj.2012.127  0.771
2012 MacGurn JA, Hsu PC, Emr SD. Ubiquitin and membrane protein turnover: from cradle to grave. Annual Review of Biochemistry. 81: 231-59. PMID 22404628 DOI: 10.1146/Annurev-Biochem-060210-093619  0.524
2012 MacDonald C, Buchkovich NJ, Stringer DK, Emr SD, Piper RC. Cargo ubiquitination is essential for multivesicular body intralumenal vesicle formation. Embo Reports. 13: 331-8. PMID 22370727 DOI: 10.1038/Embor.2012.18  0.5
2011 Karotki L, Huiskonen JT, Stefan CJ, Ziółkowska NE, Roth R, Surma MA, Krogan NJ, Emr SD, Heuser J, Grünewald K, Walther TC. Eisosome proteins assemble into a membrane scaffold. The Journal of Cell Biology. 195: 889-902. PMID 22123866 DOI: 10.1083/Jcb.201104040  0.509
2011 MacGurn JA, Hsu PC, Smolka MB, Emr SD. TORC1 regulates endocytosis via Npr1-mediated phosphoinhibition of a ubiquitin ligase adaptor. Cell. 147: 1104-17. PMID 22118465 DOI: 10.1016/J.Cell.2011.09.054  0.512
2011 Shi Y, Stefan CJ, Rue SM, Teis D, Emr SD. Two novel WD40 domain-containing proteins, Ere1 and Ere2, function in the retromer-mediated endosomal recycling pathway. Molecular Biology of the Cell. 22: 4093-107. PMID 21880895 DOI: 10.1091/Mbc.E11-05-0440  0.58
2011 McMurray MA, Stefan CJ, Wemmer M, Odorizzi G, Emr SD, Thorner J. Genetic interactions with mutations affecting septin assembly reveal ESCRT functions in budding yeast cytokinesis. Biological Chemistry. 392: 699-712. PMID 21824003 DOI: 10.1515/Bc.2011.091  0.767
2011 Henne WM, Buchkovich NJ, Emr SD. The ESCRT pathway. Developmental Cell. 21: 77-91. PMID 21763610 DOI: 10.1016/J.Devcel.2011.05.015  0.745
2011 Han BK, Emr SD. Phosphoinositide [PI(3,5)P2] lipid-dependent regulation of the general transcriptional regulator Tup1. Genes & Development. 25: 984-95. PMID 21536737 DOI: 10.1101/Gad.1998611  0.39
2011 Stefan CJ, Manford AG, Baird D, Yamada-Hanff J, Mao Y, Emr SD. Osh proteins regulate phosphoinositide metabolism at ER-plasma membrane contact sites. Cell. 144: 389-401. PMID 21295699 DOI: 10.1016/J.Cell.2010.12.034  0.512
2010 Garrenton LS, Stefan CJ, McMurray MA, Emr SD, Thorner J. Pheromone-induced anisotropy in yeast plasma membrane phosphatidylinositol-4,5-bisphosphate distribution is required for MAPK signaling. Proceedings of the National Academy of Sciences of the United States of America. 107: 11805-10. PMID 20547860 DOI: 10.1073/Pnas.1005817107  0.482
2010 Manford A, Xia T, Saxena AK, Stefan C, Hu F, Emr SD, Mao Y. Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function. The Embo Journal. 29: 1489-98. PMID 20389282 DOI: 10.1038/Emboj.2010.57  0.357
2010 Teis D, Saksena S, Judson BL, Emr SD. ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation. The Embo Journal. 29: 871-83. PMID 20134403 DOI: 10.1038/Emboj.2009.408  0.372
2010 Stefan C, Audhya A, Emr SD. FYVE domains in membrane trafficking and cell signaling Handbook of Cell Signaling, 2/E. 2: 1111-1121. DOI: 10.1016/B978-0-12-374145-5.00138-8  0.64
2009 Emr S, Glick BS, Linstedt AD, Lippincott-Schwartz J, Luini A, Malhotra V, Marsh BJ, Nakano A, Pfeffer SR, Rabouille C, Rothman JE, Warren G, Wieland FT. Journeys through the Golgi--taking stock in a new era. The Journal of Cell Biology. 187: 449-53. PMID 19948493 DOI: 10.1083/Jcb.200909011  0.393
2009 Tran JH, Chen CJ, Emr S, Schekman R. Cargo sorting into multivesicular bodies in vitro. Proceedings of the National Academy of Sciences of the United States of America. 106: 17395-400. PMID 19805166 DOI: 10.1073/Pnas.0909473106  0.804
2009 Teis D, Saksena S, Emr SD. SnapShot: the ESCRT machinery. Cell. 137: 182-182.e1. PMID 19345195 DOI: 10.1016/J.Cell.2009.03.027  0.359
2009 Saksena S, Emr SD. ESCRTs and human disease. Biochemical Society Transactions. 37: 167-72. PMID 19143624 DOI: 10.1042/Bst0370167  0.428
2009 Saksena S, Wahlman J, Teis D, Johnson AE, Emr SD. Functional reconstitution of ESCRT-III assembly and disassembly. Cell. 136: 97-109. PMID 19135892 DOI: 10.1016/J.Cell.2008.11.013  0.561
2008 Baird D, Stefan C, Audhya A, Weys S, Emr SD. Assembly of the PtdIns 4-kinase Stt4 complex at the plasma membrane requires Ypp1 and Efr3. The Journal of Cell Biology. 183: 1061-74. PMID 19075114 DOI: 10.1083/Jcb.200804003  0.714
2008 Lin CH, MacGurn JA, Chu T, Stefan CJ, Emr SD. Arrestin-related ubiquitin-ligase adaptors regulate endocytosis and protein turnover at the cell surface. Cell. 135: 714-25. PMID 18976803 DOI: 10.1016/J.Cell.2008.09.025  0.529
2008 Teis D, Saksena S, Emr SD. Ordered assembly of the ESCRT-III complex on endosomes is required to sequester cargo during MVB formation. Developmental Cell. 15: 578-89. PMID 18854142 DOI: 10.1016/J.Devcel.2008.08.013  0.416
2008 Ghazi-Tabatabai S, Saksena S, Short JM, Pobbati AV, Veprintsev DB, Crowther RA, Emr SD, Egelman EH, Williams RL. Structure and disassembly of filaments formed by the ESCRT-III subunit Vps24. Structure (London, England : 1993). 16: 1345-56. PMID 18786397 DOI: 10.1016/J.Str.2008.06.010  0.427
2008 Botelho RJ, Efe JA, Teis D, Emr SD. Assembly of a Fab1 phosphoinositide kinase signaling complex requires the Fig4 phosphoinositide phosphatase. Molecular Biology of the Cell. 19: 4273-86. PMID 18653468 DOI: 10.1091/Mbc.E08-04-0405  0.45
2008 Rue SM, Mattei S, Saksena S, Emr SD. Novel Ist1-Did2 complex functions at a late step in multivesicular body sorting. Molecular Biology of the Cell. 19: 475-84. PMID 18032584 DOI: 10.1091/Mbc.E07-07-0694  0.533
2007 Saksena S, Sun J, Chu T, Emr SD. ESCRTing proteins in the endocytic pathway. Trends in Biochemical Sciences. 32: 561-73. PMID 17988873 DOI: 10.1016/J.Tibs.2007.09.010  0.519
2007 Obita T, Saksena S, Ghazi-Tabatabai S, Gill DJ, Perisic O, Emr SD, Williams RL. Structural basis for selective recognition of ESCRT-III by the AAA ATPase Vps4. Nature. 449: 735-9. PMID 17928861 DOI: 10.1038/Nature06171  0.487
2007 Efe JA, Botelho RJ, Emr SD. Atg18 regulates organelle morphology and Fab1 kinase activity independent of its membrane recruitment by phosphatidylinositol 3,5-bisphosphate. Molecular Biology of the Cell. 18: 4232-44. PMID 17699591 DOI: 10.1091/Mbc.E07-04-0301  0.531
2007 Gill DJ, Teo H, Sun J, Perisic O, Veprintsev DB, Vallis Y, Emr SD, Williams RL. Structural studies of phosphoinositide 3-kinase-dependent traffic to multivesicular bodies. Biochemical Society Symposium. 47-57. PMID 17233579 DOI: 10.1042/Bss0740047  0.534
2007 Gill DJ, Teo H, Sun J, Perisic O, Veprintsev DB, Emr SD, Williams RL. Structural insight into the ESCRT-I/-II link and its role in MVB trafficking. The Embo Journal. 26: 600-12. PMID 17215868 DOI: 10.1038/Sj.Emboj.7601501  0.414
2007 Emr SD, Efe J, Botelho R, Audhya J, Baird D, Stefan C. Phosphoinositide Lipid Signaling in the Regulation of Membrane Trafficking and Organelle Identity The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A37-B  0.419
2006 Chu T, Sun J, Saksena S, Emr SD. New component of ESCRT-I regulates endosomal sorting complex assembly. The Journal of Cell Biology. 175: 815-23. PMID 17145965 DOI: 10.1083/Jcb.200608053  0.441
2006 Morozova N, Liang Y, Tokarev AA, Chen SH, Cox R, Andrejic J, Lipatova Z, Sciorra VA, Emr SD, Segev N. TRAPPII subunits are required for the specificity switch of a Ypt-Rab GEF. Nature Cell Biology. 8: 1263-9. PMID 17041589 DOI: 10.1038/Ncb1489  0.46
2006 Tabuchi M, Audhya A, Parsons AB, Boone C, Emr SD. The phosphatidylinositol 4,5-biphosphate and TORC2 binding proteins Slm1 and Slm2 function in sphingolipid regulation. Molecular and Cellular Biology. 26: 5861-75. PMID 16847337 DOI: 10.1128/Mcb.02403-05  0.704
2006 Hurley JH, Emr SD. The ESCRT complexes: structure and mechanism of a membrane-trafficking network. Annual Review of Biophysics and Biomolecular Structure. 35: 277-98. PMID 16689637 DOI: 10.1146/Annurev.Biophys.35.040405.102126  0.507
2006 Kostelansky MS, Sun J, Lee S, Kim J, Ghirlando R, Hierro A, Emr SD, Hurley JH. Structural and functional organization of the ESCRT-I trafficking complex. Cell. 125: 113-26. PMID 16615894 DOI: 10.1016/J.Cell.2006.01.049  0.375
2006 Teo H, Gill DJ, Sun J, Perisic O, Veprintsev DB, Vallis Y, Emr SD, Williams RL. ESCRT-I core and ESCRT-II GLUE domain structures reveal role for GLUE in linking to ESCRT-I and membranes. Cell. 125: 99-111. PMID 16615893 DOI: 10.1016/J.Cell.2006.01.047  0.443
2005 Parrish WR, Stefan CJ, Emr SD. PtdIns(3)P accumulation in triple lipid-phosphatase-deletion mutants triggers lethal hyperactivation of the Rho1p/Pkc1p cell-integrity MAP kinase pathway. Journal of Cell Science. 118: 5589-601. PMID 16306222 DOI: 10.1242/Jcs.02649  0.447
2005 Efe JA, Plattner F, Hulo N, Kressler D, Emr SD, Deloche O. Yeast Mon2p is a highly conserved protein that functions in the cytoplasm-to-vacuole transport pathway and is required for Golgi homeostasis. Journal of Cell Science. 118: 4751-64. PMID 16219684 DOI: 10.1242/Jcs.02599  0.556
2005 Efe JA, Botelho RJ, Emr SD. The Fab1 phosphatidylinositol kinase pathway in the regulation of vacuole morphology. Current Opinion in Cell Biology. 17: 402-8. PMID 15975782 DOI: 10.1016/J.Ceb.2005.06.002  0.473
2005 Stefan CJ, Padilla SM, Audhya A, Emr SD. The phosphoinositide phosphatase Sjl2 is recruited to cortical actin patches in the control of vesicle formation and fission during endocytosis. Molecular and Cellular Biology. 25: 2910-23. PMID 15798181 DOI: 10.1128/Mcb.25.8.2910-2923.2005  0.749
2005 Shohdy N, Efe JA, Emr SD, Shuman HA. Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking. Proceedings of the National Academy of Sciences of the United States of America. 102: 4866-71. PMID 15781869 DOI: 10.1073/Pnas.0501315102  0.527
2005 Sciorra VA, Audhya A, Parsons AB, Segev N, Boone C, Emr SD. Synthetic genetic array analysis of the PtdIns 4-kinase Pik1p identifies components in a Golgi-specific Ypt31/rab-GTPase signaling pathway. Molecular Biology of the Cell. 16: 776-93. PMID 15574876 DOI: 10.1091/Mbc.E04-08-0700  0.724
2004 Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/Science.306.5700.1290  0.601
2004 Miller AL, Suntharalingam M, Johnson SL, Audhya A, Emr SD, Wente SR. Cytoplasmic inositol hexakisphosphate production is sufficient for mediating the Gle1-mRNA export pathway. The Journal of Biological Chemistry. 279: 51022-32. PMID 15459192 DOI: 10.1074/Jbc.M409394200  0.669
2004 Audhya A, Loewith R, Parsons AB, Gao L, Tabuchi M, Zhou H, Boone C, Hall MN, Emr SD. Genome-wide lethality screen identifies new PI4,5P2 effectors that regulate the actin cytoskeleton. The Embo Journal. 23: 3747-57. PMID 15372071 DOI: 10.1038/Sj.Emboj.7600384  0.681
2004 Hierro A, Sun J, Rusnak AS, Kim J, Prag G, Emr SD, Hurley JH. Structure of the ESCRT-II endosomal trafficking complex. Nature. 431: 221-5. PMID 15329733 DOI: 10.1038/Nature02914  0.49
2004 Parrish WR, Stefan CJ, Emr SD. Essential role for the myotubularin-related phosphatase Ymr1p and the synaptojanin-like phosphatases Sjl2p and Sjl3p in regulation of phosphatidylinositol 3-phosphate in yeast. Molecular Biology of the Cell. 15: 3567-79. PMID 15169871 DOI: 10.1091/Mbc.E04-03-0209  0.484
2004 Alam SL, Sun J, Payne M, Welch BD, Blake BK, Davis DR, Meyer HH, Emr SD, Sundquist WI. Ubiquitin interactions of NZF zinc fingers. The Embo Journal. 23: 1411-21. PMID 15029239 DOI: 10.1038/Sj.Emboj.7600114  0.421
2004 Yu JW, Mendrola JM, Audhya A, Singh S, Keleti D, DeWald DB, Murray D, Emr SD, Lemmon MA. Genome-wide analysis of membrane targeting by S. cerevisiae pleckstrin homology domains. Molecular Cell. 13: 677-88. PMID 15023338 DOI: 10.1016/S1097-2765(04)00083-8  0.79
2004 Katzmann DJ, Sarkar S, Chu T, Audhya A, Emr SD. Multivesicular body sorting: ubiquitin ligase Rsp5 is required for the modification and sorting of carboxypeptidase S. Molecular Biology of the Cell. 15: 468-80. PMID 14657247 DOI: 10.1091/Mbc.E03-07-0473  0.804
2004 Rudge SA, Anderson DM, Emr SD. Vacuole size control: regulation of PtdIns(3,5)P2 levels by the vacuole-associated Vac14-Fig4 complex, a PtdIns(3,5)P2-specific phosphatase. Molecular Biology of the Cell. 15: 24-36. PMID 14528018 DOI: 10.1091/Mbc.E03-05-0297  0.449
2003 Audhya A, Emr SD. Regulation of PI4,5P2 synthesis by nuclear-cytoplasmic shuttling of the Mss4 lipid kinase. The Embo Journal. 22: 4223-36. PMID 12912920 DOI: 10.1093/Emboj/Cdg397  0.708
2003 Katzmann DJ, Stefan CJ, Babst M, Emr SD. Vps27 recruits ESCRT machinery to endosomes during MVB sorting. The Journal of Cell Biology. 162: 413-23. PMID 12900393 DOI: 10.1083/Jcb.200302136  0.78
2003 Odorizzi G, Katzmann DJ, Babst M, Audhya A, Emr SD. Bro1 is an endosome-associated protein that functions in the MVB pathway in Saccharomyces cerevisiae. Journal of Cell Science. 116: 1893-903. PMID 12668726 DOI: 10.1242/Jcs.00395  0.851
2003 Stefan C, Audhya A, Emr S. FYVE Domains in Membrane Trafficking and Cell Signaling Handbook of Cell Signaling. 2: 177-185. DOI: 10.1016/B978-012124546-7/50513-1  0.64
2002 Katzmann DJ, Odorizzi G, Emr SD. Receptor downregulation and multivesicular-body sorting. Nature Reviews. Molecular Cell Biology. 3: 893-905. PMID 12461556 DOI: 10.1038/Nrm973  0.817
2002 Malhotra V, Emr SD. Rothman and Schekman SNAREd by Lasker for trafficking. Cell. 111: 1-3. PMID 12372293 DOI: 10.1016/S0092-8674(02)01008-5  0.34
2002 Han GS, Audhya A, Markley DJ, Emr SD, Carman GM. The Saccharomyces cerevisiae LSB6 gene encodes phosphatidylinositol 4-kinase activity. The Journal of Biological Chemistry. 277: 47709-18. PMID 12361950 DOI: 10.1074/Jbc.M207996200  0.7
2002 Burda P, Padilla SM, Sarkar S, Emr SD. Retromer function in endosome-to-Golgi retrograde transport is regulated by the yeast Vps34 PtdIns 3-kinase. Journal of Cell Science. 115: 3889-900. PMID 12244127 DOI: 10.1242/Jcs.00090  0.547
2002 Babst M, Katzmann DJ, Snyder WB, Wendland B, Emr SD. Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body. Developmental Cell. 3: 283-9. PMID 12194858 DOI: 10.1016/S1534-5807(02)00219-8  0.819
2002 Babst M, Katzmann DJ, Estepa-Sabal EJ, Meerloo T, Emr SD. Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting. Developmental Cell. 3: 271-82. PMID 12194857 DOI: 10.1016/S1534-5807(02)00220-4  0.784
2002 Wurmser AE, Emr SD. Novel PtdIns(3)P-binding protein Etf1 functions as an effector of the Vps34 PtdIns 3-kinase in autophagy. The Journal of Cell Biology. 158: 761-72. PMID 12186856 DOI: 10.1083/Jcb.200112050  0.552
2002 Nice DC, Sato TK, Stromhaug PE, Emr SD, Klionsky DJ. Cooperative binding of the cytoplasm to vacuole targeting pathway proteins, Cvt13 and Cvt20, to phosphatidylinositol 3-phosphate at the pre-autophagosomal structure is required for selective autophagy. The Journal of Biological Chemistry. 277: 30198-207. PMID 12048214 DOI: 10.1074/Jbc.M204736200  0.568
2002 Audhya A, Emr SD. Stt4 PI 4-kinase localizes to the plasma membrane and functions in the Pkc1-mediated MAP kinase cascade. Developmental Cell. 2: 593-605. PMID 12015967 DOI: 10.1016/S1534-5807(02)00168-5  0.708
2002 Zhong Q, Lazar CS, Tronchère H, Sato T, Meerloo T, Yeo M, Songyang Z, Emr SD, Gill GN. Endosomal localization and function of sorting nexin 1. Proceedings of the National Academy of Sciences of the United States of America. 99: 6767-72. PMID 11997453 DOI: 10.1073/Pnas.092142699  0.477
2002 Shih SC, Katzmann DJ, Schnell JD, Sutanto M, Emr SD, Hicke L. Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis. Nature Cell Biology. 4: 389-93. PMID 11988742 DOI: 10.1038/Ncb790  0.847
2002 Gary JD, Sato TK, Stefan CJ, Bonangelino CJ, Weisman LS, Emr SD. Regulation of Fab1 phosphatidylinositol 3-phosphate 5-kinase pathway by Vac7 protein and Fig4, a polyphosphoinositide phosphatase family member. Molecular Biology of the Cell. 13: 1238-51. PMID 11950935 DOI: 10.1091/Mbc.01-10-0498  0.469
2002 Bonangelino CJ, Nau JJ, Duex JE, Brinkman M, Wurmser AE, Gary JD, Emr SD, Weisman LS. Osmotic stress-induced increase of phosphatidylinositol 3,5-bisphosphate requires Vac14p, an activator of the lipid kinase Fab1p. The Journal of Cell Biology. 156: 1015-28. PMID 11889142 DOI: 10.1083/Jcb.200201002  0.3
2002 Stefan CJ, Audhya A, Emr SD. The yeast synaptojanin-like proteins control the cellular distribution of phosphatidylinositol (4,5)-bisphosphate. Molecular Biology of the Cell. 13: 542-57. PMID 11854411 DOI: 10.1091/Mbc.01-10-0476  0.723
2001 Rieder SE, Emr SD. Isolation of subcellular fractions from the yeast Saccharomyces cerevisiae. Current Protocols in Cell Biology / Editorial Board, Juan S. Bonifacino ... [Et Al.]. Unit 3.8. PMID 18228360 DOI: 10.1002/0471143030.Cb0308S08  0.38
2001 Sato TK, Overduin M, Emr SD. Location, location, location: membrane targeting directed by PX domains. Science (New York, N.Y.). 294: 1881-5. PMID 11729306 DOI: 10.1126/Science.1065763  0.544
2001 Foti M, Audhya A, Emr SD. Sac1 lipid phosphatase and Stt4 phosphatidylinositol 4-kinase regulate a pool of phosphatidylinositol 4-phosphate that functions in the control of the actin cytoskeleton and vacuole morphology. Molecular Biology of the Cell. 12: 2396-411. PMID 11514624 DOI: 10.1091/Mbc.12.8.2396  0.697
2001 Katzmann DJ, Babst M, Emr SD. Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I. Cell. 106: 145-55. PMID 11511343 DOI: 10.1016/S0092-8674(01)00434-2  0.763
2001 Simonsen A, Wurmser AE, Emr SD, Stenmark H. The role of phosphoinositides in membrane transport. Current Opinion in Cell Biology. 13: 485-92. PMID 11454456 DOI: 10.1016/S0955-0674(00)00240-4  0.531
2001 Cheever ML, Sato TK, de Beer T, Kutateladze TG, Emr SD, Overduin M. Phox domain interaction with PtdIns(3)P targets the Vam7 t-SNARE to vacuole membranes. Nature Cell Biology. 3: 613-8. PMID 11433291 DOI: 10.1038/35083000  0.468
2001 Peterson MR, Emr SD. The class C Vps complex functions at multiple stages of the vacuolar transport pathway. Traffic (Copenhagen, Denmark). 2: 476-86. PMID 11422941 DOI: 10.1034/J.1600-0854.2001.20705.X  0.437
2001 Costaguta G, Stefan CJ, Bensen ES, Emr SD, Payne GS. Yeast Gga coat proteins function with clathrin in Golgi to endosome transport. Molecular Biology of the Cell. 12: 1885-96. PMID 11408593 DOI: 10.1091/Mbc.12.6.1885  0.704
2001 Darsow T, Katzmann DJ, Cowles CR, Emr SD. Vps41p function in the alkaline phosphatase pathway requires homo-oligomerization and interaction with AP-3 through two distinct domains. Molecular Biology of the Cell. 12: 37-51. PMID 11160821 DOI: 10.1091/Mbc.12.1.37  0.774
2000 Babst M, Odorizzi G, Estepa EJ, Emr SD. Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking. Traffic (Copenhagen, Denmark). 1: 248-58. PMID 11208108 DOI: 10.1034/J.1600-0854.2000.010307.X  0.784
2000 Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science (New York, N.Y.). 290: 1717-21. PMID 11099404 DOI: 10.1126/Science.290.5497.1717  0.559
2000 Wurmser AE, Sato TK, Emr SD. New component of the vacuolar class C-Vps complex couples nucleotide exchange on the Ypt7 GTPase to SNARE-dependent docking and fusion. The Journal of Cell Biology. 151: 551-62. PMID 11062257 DOI: 10.1083/Jcb.151.3.551  0.433
2000 Darsow T, Odorizzi G, Emr SD. Invertase fusion proteins for analysis of protein trafficking in yeast. Methods in Enzymology. 327: 95-106. PMID 11044977 DOI: 10.1016/S0076-6879(00)27270-4  0.768
2000 Sato TK, Rehling P, Peterson MR, Emr SD. Class C Vps protein complex regulates vacuolar SNARE pairing and is required for vesicle docking/fusion. Molecular Cell. 6: 661-71. PMID 11030345 DOI: 10.1016/S1097-2765(00)00064-2  0.425
2000 Audhya A, Foti M, Emr SD. Distinct roles for the yeast phosphatidylinositol 4-kinases, Stt4p and Pik1p, in secretion, cell growth, and organelle membrane dynamics. Molecular Biology of the Cell. 11: 2673-89. PMID 10930462 DOI: 10.1091/Mbc.11.8.2673  0.711
2000 Odorizzi G, Babst M, Emr SD. Phosphoinositide signaling and the regulation of membrane trafficking in yeast. Trends in Biochemical Sciences. 25: 229-35. PMID 10782093 DOI: 10.1016/S0968-0004(00)01543-7  0.746
1999 Rehling P, Darsow T, Katzmann DJ, Emr SD. Formation of AP-3 transport intermediates requires Vps41 function. Nature Cell Biology. 1: 346-53. PMID 10559961 DOI: 10.1038/14037  0.76
1999 Abeliovich H, Darsow T, Emr SD. Cytoplasm to vacuole trafficking of aminopeptidase I requires a t-SNARE-Sec1p complex composed of Tlg2p and Vps45p. The Embo Journal. 18: 6005-16. PMID 10545112 DOI: 10.1093/Emboj/18.21.6005  0.474
1999 Wendland B, Steece KE, Emr SD. Yeast epsins contain an essential N-terminal ENTH domain, bind clathrin and are required for endocytosis. The Embo Journal. 18: 4383-93. PMID 10449404 DOI: 10.1093/Emboj/18.16.4383  0.72
1999 Kutateladze TG, Ogburn KD, Watson WT, de Beer T, Emr SD, Burd CG, Overduin M. Phosphatidylinositol 3-phosphate recognition by the FYVE domain. Molecular Cell. 3: 805-11. PMID 10394369 DOI: 10.1016/S1097-2765(01)80013-7  0.402
1999 Luan P, Balch WE, Emr SD, Burd CG. Molecular dissection of guanine nucleotide dissociation inhibitor function in vivo. Rab-independent binding to membranes and role of Rab recycling factors. The Journal of Biological Chemistry. 274: 14806-17. PMID 10329679 DOI: 10.1074/Jbc.274.21.14806  0.55
1999 Jørgensen MU, Emr SD, Winther JR. Ligand recognition and domain structure of Vps10p, a vacuolar protein sorting receptor in Saccharomyces cerevisiae. European Journal of Biochemistry / Febs. 260: 461-9. PMID 10095782 DOI: 10.1046/J.1432-1327.1999.00176.X  0.352
1999 Wurmser AE, Gary JD, Emr SD. Phosphoinositide 3-kinases and their FYVE domain-containing effectors as regulators of vacuolar/lysosomal membrane trafficking pathways. The Journal of Biological Chemistry. 274: 9129-32. PMID 10092582 DOI: 10.1074/Jbc.274.14.9129  0.473
1999 Gaynor EC, Mondésert G, Grimme SJ, Reed SI, Orlean P, Emr SD. MCD4 encodes a conserved endoplasmic reticulum membrane protein essential for glycosylphosphatidylinositol anchor synthesis in yeast. Molecular Biology of the Cell. 10: 627-48. PMID 10069808 DOI: 10.1091/Mbc.10.3.627  0.596
1999 Kay BK, Yamabhai M, Wendland B, Emr SD. Identification of a novel domain shared by putative components of the endocytic and cytoskeletal machinery. Protein Science : a Publication of the Protein Society. 8: 435-8. PMID 10048338 DOI: 10.1110/Ps.8.2.435  0.629
1999 Peterson MR, Burd CG, Emr SD. Vac1p coordinates Rab and phosphatidylinositol 3-kinase signaling in Vps45p-dependent vesicle docking/fusion at the endosome. Current Biology : Cb. 9: 159-62. PMID 10021387 DOI: 10.1016/S0960-9822(99)80071-2  0.573
1998 Odorizzi G, Babst M, Emr SD. Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body. Cell. 95: 847-58. PMID 9865702 DOI: 10.1016/S0092-8674(00)81707-9  0.768
1998 Burd CG, Babst M, Emr SD. Novel pathways, membrane coats and PI kinase regulation in yeast lysosomal trafficking. Seminars in Cell & Developmental Biology. 9: 527-33. PMID 9835640 DOI: 10.1006/Scdb.1998.0255  0.58
1998 Gary JD, Wurmser AE, Bonangelino CJ, Weisman LS, Emr SD. Fab1p is essential for PtdIns(3)P 5-kinase activity and the maintenance of vacuolar size and membrane homeostasis. The Journal of Cell Biology. 143: 65-79. PMID 9763421 DOI: 10.1083/Jcb.143.1.65  0.469
1998 Wurmser AE, Emr SD. Phosphoinositide signaling and turnover: PtdIns(3)P, a regulator of membrane traffic, is transported to the vacuole and degraded by a process that requires lumenal vacuolar hydrolase activities. The Embo Journal. 17: 4930-42. PMID 9724630 DOI: 10.1093/Emboj/17.17.4930  0.454
1998 Darsow T, Burd CG, Emr SD. Acidic di-leucine motif essential for AP-3-dependent sorting and restriction of the functional specificity of the Vam3p vacuolar t-SNARE. The Journal of Cell Biology. 142: 913-22. PMID 9722605 DOI: 10.1083/Jcb.142.4.913  0.566
1998 Wendland B, Emr SD, Riezman H. Protein traffic in the yeast endocytic and vacuolar protein sorting pathways. Current Opinion in Cell Biology. 10: 513-22. PMID 9719873 DOI: 10.1016/S0955-0674(98)80067-7  0.747
1998 Gaynor EC, Graham TR, Emr SD. COPI in ER/Golgi and intra-Golgi transport: Do yeast COPI mutants point the way? Biochimica Et Biophysica Acta - Molecular Cell Research. 1404: 33-51. PMID 9714721 DOI: 10.1016/S0167-4889(98)00045-7  0.739
1998 Odorizzi G, Cowles CR, Emr SD. The AP-3 complex: a coat of many colours. Trends in Cell Biology. 8: 282-8. PMID 9714600 DOI: 10.1016/S0962-8924(98)01295-1  0.716
1998 Sato TK, Darsow T, Emr SD. Vam7p, a SNAP-25-like molecule, and Vam3p, a syntaxin homolog, function together in yeast vacuolar protein trafficking Molecular and Cellular Biology. 18: 5308-5319. PMID 9710615 DOI: 10.1128/Mcb.18.9.5308  0.537
1998 Burd CG, Emr SD. Phosphatidylinositol(3)-phosphate signaling mediated by specific binding to RING FYVE domains. Molecular Cell. 2: 157-62. PMID 9702203 DOI: 10.1016/S1097-2765(00)80125-2  0.504
1998 Seaman MNJ, McCaffery JM, Emr SD. A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast Journal of Cell Biology. 142: 665-681. PMID 9700157 DOI: 10.1083/Jcb.142.3.665  0.501
1998 Babst M, Wendland B, Estepa EJ, Emr SD. The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function Embo Journal. 17: 2982-2993. PMID 9606181 DOI: 10.1093/Emboj/17.11.2982  0.748
1998 Wendland B, Emr SD. Pan1p, yeast eps15, functions as a multivalent adaptor that coordinates protein-protein interactions essential for endocytosis Journal of Cell Biology. 141: 71-84. PMID 9531549 DOI: 10.1083/Jcb.141.1.71  0.76
1998 Gaynor EC, Chen CY, Emr SD, Graham TR. ARF is required for maintenance of yeast Golgi and endosome structure and function Molecular Biology of the Cell. 9: 653-670. PMID 9487133 DOI: 10.1091/Mbc.9.3.653  0.726
1997 DeWald DB, Wurmser AE, Emr SD. Regulation of the Saccharomyces cerevisiae Vps34p phosphatidylinositol 3-kinase Biochemical Society Transactions. 25: 1141-1146. PMID 9449964  0.651
1997 Rieder SE, Emr SD. A novel RING finger protein complex essential for a late step in protein transport to the yeast vacuole Molecular Biology of the Cell. 8: 2307-2327. PMID 9362071 DOI: 10.1091/Mbc.8.11.2307  0.593
1997 Cowles CR, Odorizzi G, Payne GS, Emr SD. The AP-3 adaptor complex is essential for cargo-selective transport to the yeast vacuole. Cell. 91: 109-18. PMID 9335339 DOI: 10.1016/S0092-8674(01)80013-1  0.8
1997 Horazdovsky BF, Davies BA, Seaman MN, McLaughlin SA, Yoon S, Emr SD. A sorting nexin-1 homologue, Vps5p, forms a complex with Vps17p and is required for recycling the vacuolar protein-sorting receptor. Molecular Biology of the Cell. 8: 1529-41. PMID 9285823 DOI: 10.1091/Mbc.8.8.1529  0.806
1997 Darsow T, Rieder SE, Emr SD. A multispecificity syntaxin homologue, Vam3p, essential for autophagic and biosynthetic protein transport to the vacuole Journal of Cell Biology. 138: 517-529. PMID 9245783 DOI: 10.1083/Jcb.138.3.517  0.556
1997 Burd CG, Peterson M, Cowles CR, Emr SD. A novel Sec18p/NSF-dependent complex required for Golgi-to-endosome transport in yeast. Molecular Biology of the Cell. 8: 1089-104. PMID 9201718 DOI: 10.1091/Mbc.8.6.1089  0.586
1997 Cowles CR, Snyder WB, Burd CG, Emr SD. Novel Golgi to vacuole delivery pathway in yeast: identification of a sorting determinant and required transport component. The Embo Journal. 16: 2769-82. PMID 9184222 DOI: 10.1093/Emboj/16.10.2769  0.551
1997 Radisky DC, Snyder WB, Emr SD, Kaplan J. Characterization of VPS41, a gene required for vacuolar trafficking and high-affinity iron transport in yeast. Proceedings of the National Academy of Sciences of the United States of America. 94: 5662-6. PMID 9159129 DOI: 10.1073/Pnas.94.11.5662  0.498
1997 Babst M, Sato TK, Banta LM, Emr SD. Endosomal transport function in yeast requires a novel AAA-type ATPase, Vps4p Embo Journal. 16: 1820-1831. PMID 9155008 DOI: 10.1093/Emboj/16.8.1820  0.571
1997 Seaman MNJ, Marcusson EG, Cereghino JL, Emr SD. Endosome to Golgi retrieval of the vacuolar protein sorting receptor, Vps10p, requires the function of the VPS29, VPS30, and VPS35 gene products Journal of Cell Biology. 137: 79-92. PMID 9105038 DOI: 10.1083/Jcb.137.1.79  0.564
1997 Gaynor EC, Emr SD. COPI-independent anterograde transport: Cargo-selective ER to Golgi protein transport in yeast COPI mutants Journal of Cell Biology. 136: 789-802. PMID 9049245 DOI: 10.1083/Jcb.136.4.789  0.511
1997 Emr SD, Slack JH, Wurmser A. Phosphoinositide signaling essential for protein sorting in the secretory pathway Faseb Journal. 11: A1010.  0.34
1996 Wendland B, Michael McCaffery J, Xiao Q, Emr SD. A novel fluorescence-activated cell sorter-based screen for yeast endocytosis mutants identifies a yeast homologue of mammalian eps15 Journal of Cell Biology. 135: 1485-1500. PMID 8978817 DOI: 10.1083/Jcb.135.6.1485  0.733
1996 Horazdovsky BF, Cowles CR, Mustol P, Holmes M, Emr SD. A novel RING finger protein, Vps8p, functionally interacts with the small GTPase, Vps21p, to facilitate soluble vacuolar protein localization0 Journal of Biological Chemistry. 271: 33607-33615. PMID 8969229 DOI: 10.1074/Jbc.271.52.33607  0.815
1996 Rieder SE, Banta LM, Köhrer K, McCaffery JM, Emr SD. Multilamellar endosome-like compartment accumulates in the yeast vps28 vacuolar protein sorting mutant Molecular Biology of the Cell. 7: 985-999. PMID 8817003 DOI: 10.1091/Mbc.7.6.985  0.573
1996 Seaman MN, Burd CG, Emr SD. Receptor signalling and the regulation of endocytic membrane transport. Current Opinion in Cell Biology. 8: 549-56. PMID 8791448 DOI: 10.1016/S0955-0674(96)80034-2  0.536
1996 Becherer KA, Rieder SE, Emr SD, Jones EW. Novel syntaxin homologue, Pep12p, required for the sorting of lumenal hydrolases to the lysosome-like vacuole in yeast Molecular Biology of the Cell. 7: 579-594. PMID 8730101 DOI: 10.1091/Mbc.7.4.579  0.556
1996 Westphal V, Marcusson EG, Winther JR, Emr SD, Van Den Hazel HB. Multiple pathways for vacuolar sorting of yeast proteinase A Journal of Biological Chemistry. 271: 11865-11870. PMID 8662642 DOI: 10.1074/Jbc.271.20.11865  0.468
1996 Burd CG, Mustol PA, Schu PV, Emr SD. A yeast protein related to a mammalian Ras-binding protein, Vps9p, is required for localization of vacuolar proteins. Molecular and Cellular Biology. 16: 2369-77. PMID 8628304 DOI: 10.1128/Mcb.16.5.2369  0.551
1996 De Camilli P, Emr SD, McPherson PS, Novick P. Phosphoinositides as regulators in membrane traffic. Science (New York, N.Y.). 271: 1533-9. PMID 8599109 DOI: 10.1126/Science.271.5255.1533  0.69
1996 Horazdovsky BF, Stack JH, Emr SD. Protein sorting to the yeast vacuole Membrane Protein Transport. 3: 119-163. DOI: 10.1016/S1874-592X(96)80006-0  0.761
1995 Stack JH, Herman PK, DeWald DB, Marcusson EG, Cereghino JL, Horazdovsky BF, Emr SD. Novel protein kinase/phosphatidylinositol 3-kinase complex essential for receptor-mediated protein sorting to the vacuole in yeast Cold Spring Harbor Symposia On Quantitative Biology. 60: 157-170. PMID 8824388 DOI: 10.1101/Sqb.1995.060.01.019  0.825
1995 Takegawa K, DeWald DB, Emr SD. Schizosaccharomyces pombe Vps34p, a phosphatidylinositol-specific PI 3-kinase essential for normal cell growth and vacuole morphology Journal of Cell Science. 108: 3745-3756. PMID 8719881  0.728
1995 Stack JH, Horazdovsky B, Emr SD. Receptor-mediated protein sorting to the vacuole in yeast: Roles for a Protein Kinase, a Lipid Kinase and GTP-Binding Proteins Annual Review of Cell and Developmental Biology. 11: 1-33. PMID 8689553 DOI: 10.1146/Annurev.Cb.11.110195.000245  0.803
1995 Cereghino JL, Marcusson EG, Emr SD. The cytoplasmic tail domain of the vacuolar protein sorting receptor Vps10p and a subset of VPS gene products regulate receptor stability, function, and localization Molecular Biology of the Cell. 6: 1089-1102. PMID 8534908 DOI: 10.1091/Mbc.6.9.1089  0.485
1995 Stack JH, DeWald DB, Takegawa K, Emr SD. Vesicle-mediated protein transport: Regulatory interactions between the Vps15 protein kinase and the Vps34 PtdIns 3-kinase essential for protein sorting to the vacuole in yeast Journal of Cell Biology. 129: 321-334. PMID 7721937 DOI: 10.1083/Jcb.129.2.321  0.789
1995 Yamamoto A, Dewald DB, Boronenkov IV, Anderson RA, Emr SD, Koshland D. Novel PI(4)P 5-kinase homologue, Fab1p, essential for normal vacuole function and morphology in yeast Molecular Biology of the Cell. 6: 525-539. PMID 7663021 DOI: 10.1091/Mbc.6.5.525  0.762
1995 Brown WJ, DeWald DB, Emr SD, Plutner H, Balch WE. Role for phosphatidylinositol 3-kinase in the sorting and transport of newly synthesized lysosomal enzymes in mammalian cells Journal of Cell Biology. 130: 781-796. PMID 7642697 DOI: 10.1083/Jcb.130.4.781  0.704
1995 Zhou K, Takegawa K, Emr SD, Firtel RA. A phosphatidylinositol (PI) kinase gene family in Dictyostelium discoideum: Biological roles of putative mammalian p110 and yeast Vps34p PI 3-kinase homologs during growth and development Molecular and Cellular Biology. 15: 5645-5656. PMID 7565716 DOI: 10.1128/Mcb.15.10.5645  0.439
1995 Vida TA, Emr SD. A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast Journal of Cell Biology. 128: 779-792. PMID 7533169 DOI: 10.1083/Jcb.128.5.779  0.459
1995 Horazdovsky BF, DeWald DB, Emr SD. Protein transport to the yeast vacuole Current Opinion in Cell Biology. 7: 544-551. PMID 7495575 DOI: 10.1016/0955-0674(95)80012-3  0.849
1994 Marcusson EG, Horazdovsky BF, Cereghino JL, Gharakhanian E, Emr SD. The sorting receptor for yeast vacuolar carboxypeptidase Y is encoded by the VPS10 gene Cell. 77: 579-586. PMID 8187177 DOI: 10.1016/0092-8674(94)90219-4  0.794
1994 Horazdovsky BF, Busch GR, Emr SD. VPS21 encodes a rab5-like GTP binding protein that is required for the sorting of yeast vacuolar proteins. The Embo Journal. 13: 1297-309. PMID 8137814 DOI: 10.1002/J.1460-2075.1994.Tb06382.X  0.81
1994 Kodaki T, Woscholski R, Emr S, Waterfield MD, Nurse P, Parker PJ. Mammalian phosphatidylinositol 3'-kinase induces a lethal phenotype on expression in Schizosaccharomyces pombe; comparison with the VPS34 gene product. European Journal of Biochemistry. 219: 775-80. PMID 8112328 DOI: 10.1111/J.1432-1033.1994.Tb18557.X  0.404
1994 Letourneur F, Gaynor EC, Hennecke S, Démollière C, Duden R, Emr SD, Riezman H, Cosson P. Coatomer is essential for retrieval of dilysine-tagged proteins to the endoplasmic reticulum Cell. 79: 1199-1207. PMID 8001155 DOI: 10.1016/0092-8674(94)90011-6  0.487
1994 Stack JH, Emr SD. Vps34p required for yeast vacuolar protein sorting is a multiple specificity kinase that exhibits both protein kinase and phosphatidylinositol-specific PI 3-kinase activities Journal of Biological Chemistry. 269: 31552-31562. PMID 7989323  0.305
1994 Welters P, Takegawa K, Emr SD, Chrispeels MJ. AtVPS34, a phosphatidylinositol 3-kinase of Arabidopsis thaliana, is an essential protein with homology to a calcium-dependent lipid binding domain Proceedings of the National Academy of Sciences of the United States of America. 91: 11398-11402. PMID 7972072 DOI: 10.1073/Pnas.91.24.11398  0.397
1994 Graham TR, Seeger M, Payne GS, MacKay VL, Emr SD. Clathrin-dependent localization of alpha 1,3 mannosyltransferase to the Golgi complex of Saccharomyces cerevisiae. The Journal of Cell Biology. 127: 667-78. PMID 7962051 DOI: 10.1083/jcb.127.3.667  0.773
1994 Gaynor EC, Te Heesen S, Graham TR, Aebi M, Emr SD. Signal-mediated retrieval of a membrane protein from the Golgi to the ER in yeast Journal of Cell Biology. 127: 653-665. PMID 7962050 DOI: 10.1083/Jcb.127.3.653  0.739
1994 Cowles CR, Emr SD, Horazdovsky BF. Mutations in the VPS45 gene, a SEC1 homologue, result in vacuolar protein sorting defects and accumulation of membrane vesicles Journal of Cell Science. 107: 3449-3459. PMID 7706396  0.521
1993 Vida TA, Huyer G, Emr SD. Yeast vacuolar proenzymes are sorted in the late Golgi complex and transported to the vacuole via a prevacuolar endosome-like compartment Journal of Cell Biology. 121: 1245-1256. PMID 8509446 DOI: 10.1083/Jcb.121.6.1245  0.527
1993 Graham TR, Scott PA, Emr SD. Brefeldin A reversibly blocks early but not late protein transport steps in the secretory pathway Embo Journal. 12: 869-877. PMID 8458343  0.606
1993 Horazdovsky BF, Emr SD. The VPS16 gene product associates with a sedimentable protein complex and is essential for vacuolar protein sorting in yeast Journal of Biological Chemistry. 268: 4953-4962. PMID 8444873  0.457
1993 Kohrer K, Emr SD. The yeast VPS17 gene encodes a membrane-associated protein required for the sorting of soluble vacuolar hydrolases Journal of Biological Chemistry. 268: 559-569. PMID 8416961  0.518
1993 Stack JH, Herman PK, Schu PV, Emr SD. A membrane-associated complex containing the Vps15 protein kinase and the Vps34 PI 3-kinase is essential for protein sorting to the yeast lysosome-like vacuole Embo Journal. 12: 2195-2204. PMID 8387919 DOI: 10.1002/J.1460-2075.1993.Tb05867.X  0.537
1993 Schu PV, Takegawa K, Fry MJ, Stack JH, Waterfield MD, Emr SD. Phosphatidylinositol 3-kinase encoded by yeast VPS34 gene essential for protein sorting. Science (New York, N.Y.). 260: 88-91. PMID 8385367 DOI: 10.1126/Science.8385367  0.465
1993 Stack JH, Emr SD. Genetic and biochemical studies of protein sorting to the yeast vacuole Current Opinion in Cell Biology. 5: 641-646. PMID 8257606 DOI: 10.1016/0955-0674(93)90134-C  0.572
1993 Graham TR, Scott PA, Emr SD. Brefeldin A reversibly blocks early but not late protein transport steps in the yeast secretory pathway. The Embo Journal. 12: 869-877. DOI: 10.1002/J.1460-2075.1993.Tb05727.X  0.368
1992 Paravicini G, Horazdovsky BF, Emr SD. Alternative pathways for the sorting of soluble vacuolar proteins in yeast: A vps35 null mutant missorts and secretes only a subset of vacuolar hydrolases Molecular Biology of the Cell. 3: 415-427. PMID 1498362 DOI: 10.1091/Mbc.3.4.415  0.796
1992 Conradt B, Shaw J, Vida T, Emr S, Wickner W. In vitro reactions of vacuole inheritance in Saccharomyces cerevisiae. The Journal of Cell Biology. 119: 1469-79. PMID 1334958 DOI: 10.1083/Jcb.119.6.1469  0.47
1992 Herman PK, Stack JH, Emr SD. A genetic and structural analysis of the yeast Vps15 protein kinase: evidence for a direct role of Vps15p in vacuolar protein delivery: EMBO J. 10, 4049 Trends in Cell Biology. 2: 75. DOI: 10.1016/0962-8924(92)90072-U  0.461
1992 Herman PK, Stack JH, Emr SD. An essential role for a protein and lipid kinase complex in secretory protein sorting Trends in Cell Biology. 2: 363-368. DOI: 10.1016/0962-8924(92)90048-R  0.568
1991 Graham TR, Emr SD. Compartmental organization of Golgi-specific protein modification and vacuolar protein sorting events defined in a yeast sec18 (NSF) mutant Journal of Cell Biology. 114: 207-218. PMID 2071670 DOI: 10.1016/0962-8924(91)90024-4  0.706
1991 Garrett JM, Singh KK, Vonder Haar RA, Emr SD. Mitochondrial protein import: isolation and characterization of the Saccharomyces cerevisiae MFT1 gene Mgg Molecular & General Genetics. 225: 483-491. PMID 2017143 DOI: 10.1007/Bf00261691  0.455
1991 Herman PK, Stack JH, DeModena JA, Emr SD. A novel protein kinase homolog essential for protein sorting to the yeast lysosome-like vacuole Cell. 64: 425-437. PMID 1988155 DOI: 10.1016/0092-8674(91)90650-N  0.556
1991 Robinson JS, Graham TR, Emr SD. A putative zinc finger protein, Saccharomyces cerevisiae Vps18p, affects late Golgi functions required for vacuolar protein sorting and efficient α- factor prohormone maturation Molecular and Cellular Biology. 11: 5813-5824. PMID 1840635 DOI: 10.1128/Mcb.11.12.5813  0.736
1991 Herman PK, Stack JH, Emr SD. A genetic and structural analysis of the yeast Vps 15 protein kinase: Evidence for a direct role of Vps 15p in vacuolar protein delivery Embo Journal. 10: 4049-4060. PMID 1756716 DOI: 10.1002/J.1460-2075.1991.Tb04981.X  0.574
1991 Altman E, Kumamoto CA, Emr SD. Heat-shock proteins can substitute for SecB function during protein export in Escherichia coli Embo Journal. 10: 239-245. PMID 1671351 DOI: 10.1002/J.1460-2075.1991.Tb07943.X  0.349
1990 Vida TA, Graham TR, Emr SD. In vitro reconstitution of intercompartmental protein transport to the yeast vacuole Journal of Cell Biology. 111: 2871-2884. PMID 2269659 DOI: 10.1083/Jcb.111.6.2871  0.689
1990 Herman PK, Emr SD. Characterization of VPS34, a gene required for vacuolar protein sorting and vacuole segregation in Saccharomyces cerevisiae Molecular and Cellular Biology. 10: 6742-6754. PMID 2247081 DOI: 10.1128/Mcb.10.12.6742  0.55
1990 Klionsky DJ, Herman PK, Emr SD. The fungal vacuole: Composition, function, and biogenesis Microbiological Reviews. 54: 266-292. PMID 2215422 DOI: 10.1128/Mmbr.54.3.266-292.1990  0.424
1990 Altman E, Emr SD, Kumamoto CA. The presence of both the signal sequence and a region of mature LamB protein is required for the interaction of LamB with the export factor SecB Journal of Biological Chemistry. 265: 18154-18160. PMID 2211691  0.307
1990 Altman E, Bankaitis VA, Emr SD. Characterization of a region in mature LamB protein that interacts with a component of the export machinery of Escherichia coli Journal of Biological Chemistry. 265: 18148-18153. PMID 2211690  0.392
1990 Banta LM, Vida TA, Herman PK, Emr SD. Characterization of yeast Vps33p, a protein required for vacuolar protein sorting and vacuole biogenesis Molecular and Cellular Biology. 10: 4638-4649. PMID 2201898 DOI: 10.1128/Mcb.10.9.4638  0.527
1990 Klionsky DJ, Emr SD. A new class of lysosomal/vacuolar protein sorting signals Journal of Biological Chemistry. 265: 5349-5352. PMID 2180925  0.481
1990 Weisman LS, Emr SD, Wickner WT. Mutants of Saccharomyces cerevisiae that block intervacuole vesicular traffic and vacuole division and segregation. Proceedings of the National Academy of Sciences of the United States of America. 87: 1076-80. PMID 1689059 DOI: 10.1073/Pnas.87.3.1076  0.371
1989 Klonsky DJ, Emr SD. Membrane protein sorting: Biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase Embo Journal. 8: 2241-2250. PMID 2676517 DOI: 10.1002/J.1460-2075.1989.Tb08348.X  0.596
1989 Bedwell DM, Strobel SA, Yun K, Jongeward GD, Emr SD. Sequence and structural requirements of a mitochondrial protein import signal defined by saturation cassette mutagenesis. Molecular and Cellular Biology. 9: 1014-25. PMID 2524645 DOI: 10.1128/Mcb.9.3.1014  0.427
1989 Bankaitis VA, Malehorn DE, Emr SD, Greene R. The Saccharomyces cerevisiae SEC14 gene encodes a cytosolic factor that is required for transport of secretory proteins from the yeast Golgi complex Journal of Cell Biology. 108: 1271-1281. PMID 2466847 DOI: 10.1083/Jcb.108.4.1271  0.678
1988 Klionsky DJ, Banta LM, Emr SD. Intracellular sorting and processing of a yeast vacuolar hydrolase: proteinase A propeptide contains vacuolar targeting information Molecular and Cellular Biology. 8: 2105-2116. PMID 3290649 DOI: 10.1128/Mcb.8.5.2105  0.508
1988 Robinson JS, Klionsky DJ, Banta LM, Emr SD. Protein sorting in Saccharomyces cerevisiae: Isolation of mutants defective in the delivery and processing of multiple vacuolar hydrolases Molecular and Cellular Biology. 8: 4936-4948. PMID 3062374 DOI: 10.1128/Mcb.8.11.4936  0.51
1988 Eakle KA, Bernstein M, Emr SD. Characterization of a component of the yeast secretion machinery: identification of the SEC18 gene product Molecular and Cellular Biology. 8: 4098-4109. PMID 3054509 DOI: 10.1128/Mcb.8.10.4098  0.512
1988 Banta LM, Robinson JS, Klionsky DJ, Emr SD. Organelle assembly in yeast: characterization of yeast mutants defective in vacuolar biogenesis and protein sorting Journal of Cell Biology. 107: 1369-1383. PMID 3049619 DOI: 10.1083/Jcb.107.4.1369  0.482
1987 Johnson LM, Bankaitis VA, Emr SD. Distinct sequence determinants direct intracellular sorting and modification of a yeast vacuolar protease Cell. 48: 875-885. PMID 3028648 DOI: 10.1016/0092-8674(87)90084-5  0.663
1987 Bedwell DM, Klionsky DJ, Emr SD. The yeast F1-ATPase beta subunit precursor contains functionally redundant mitochondrial protein import information Molecular and Cellular Biology. 7: 4038-4047. PMID 2893254 DOI: 10.1128/Mcb.7.11.4038  0.378
1986 Bankaitis VA, Johnson LM, Emr SD. Isolation of yeast mutants defective in protein targeting to the vacuole Proceedings of the National Academy of Sciences of the United States of America. 83: 9075-9079. PMID 3538017 DOI: 10.1073/Pnas.83.23.9075  0.705
1986 Tschopp JF, Emr SD, Field C, Schekman R. GAL2 codes for a membrane-bound subunit of the galactose permease in Saccharomyces cerevisiae Journal of Bacteriology. 166: 313-318. PMID 3082856 DOI: 10.1128/Jb.166.1.313-318.1986  0.588
1986 Emr SD, Vassarotti A, Garrett J, Geller BL, Takeda M, Douglas MG. The amino terminus of the yeast F1-ATPase β-subunit precursor functions as a mitochondrial import signal Journal of Cell Biology. 102: 523-533. PMID 2868014 DOI: 10.1083/Jcb.102.2.523  0.425
1985 Schauer I, Emr S, Gross C, Schekman R. Invertase signal and mature sequence substitutions that delay intercompartmental transport of active enzyme. The Journal of Cell Biology. 100: 1664-75. PMID 3886671 DOI: 10.1083/Jcb.100.5.1664  0.569
1984 Emr SD, Schauer I, Hansen W, Esmon P, Schekman R. Invertase β-galactosidase hybrid proteins fail to be transported from the endoplasmic reticulum in Saccharomyces cerevisiae Molecular and Cellular Biology. 4: 2347-2355. PMID 6440005 DOI: 10.1128/Mcb.4.11.2347  0.602
1984 Douglas MG, Geller BL, Emr SD. Intracellular targeting and import of an F1-ATPase β-subunit-β-galactosidase hybrid protein into yeast mitochondria Proceedings of the National Academy of Sciences of the United States of America. 81: 3983-3987. PMID 6330727 DOI: 10.1073/Pnas.81.13.3983  0.357
1984 Lopilato JE, Garwin JL, Emr SD, Silhavy TJ, Beckwith JR. D-ribose metabolism in Escherichia coli K-12: genetics, regulation, and transport. Journal of Bacteriology. 158: 665-73. PMID 6327616 DOI: 10.1128/Jb.158.2.665-673.1984  0.787
1983 Emr SD, Schekman R, Flessel MC, Thorner J. An MF alpha 1-SUC2 (alpha-factor-invertase) gene fusion for study of protein localization and gene expression in yeast. Proceedings of the National Academy of Sciences of the United States of America. 80: 7080-4. PMID 6359161 DOI: 10.1073/Pnas.80.23.7080  0.539
1983 Silhavy TJ, Benson SA, Emr SD. Mechanisms of protein localization. Microbiological Reviews. 47: 313-44. PMID 6355805 DOI: 10.1128/Mmbr.47.3.313-344.1983  0.639
1983 Emr SD, Silhavy TJ. Importance of secondary structure in the signal sequence for protein secretion. Proceedings of the National Academy of Sciences of the United States of America. 80: 4599-603. PMID 6224220 DOI: 10.1073/Pnas.80.15.4599  0.703
1982 Emr SD, Silhavy TJ. Molecular components of the signal sequence that function in the initiation of protein export. The Journal of Cell Biology. 95: 689-96. PMID 6759512 DOI: 10.1083/Jcb.95.3.689  0.718
1982 Emr SD, Silhavy TJ. The signal hypothesis in bacteria. Progress in Clinical and Biological Research. 91: 3-14. PMID 6755484  0.575
1982 Shultz J, Silhavy TJ, Berman ML, Fiil N, Emr SD. A previously unidentified gene in the spc operon of Escherichia coli K12 specifies a component of the protein export machinery. Cell. 31: 227-35. PMID 6297749 DOI: 10.1016/0092-8674(82)90422-6  0.713
1981 Bassford PJ, Emr SD, Silhavy TJ, Beckwith J, Beduelle H, Clément JM, Hedgpeth J, Hofnung M. The genetics of protein secretion in Escherichia coli. Methods in Cell Biology. 23: 27-38. PMID 7035805 DOI: 10.1016/S0091-679X(08)61489-2  0.813
1981 Emr SD, Hanley-Way S, Silhavy TJ. Suppressor mutations that restore export of a protein with a defective signal sequence. Cell. 23: 79-88. PMID 7011570 DOI: 10.1016/0092-8674(81)90272-5  0.727
1980 Hall MN, Emr SD, Silhavy TJ. Genetic studies on mechanisms of protein localization in Escherichia coli K-12. Journal of Supramolecular Structure. 13: 147-63. PMID 7017277 DOI: 10.1002/Jss.400130203  0.762
1980 Emr SD, Silhavy TJ. Mutations affecting localization of an Escherichia coli outer membrane protein, the bacteriophage lambda receptor. Journal of Molecular Biology. 141: 63-90. PMID 6448927 DOI: 10.1016/S0022-2836(80)80029-5  0.739
1980 Emr SD, Hall MN, Silhavy TJ. A mechanism of protein localization: the signal hypothesis and bacteria. The Journal of Cell Biology. 86: 701-11. PMID 6447703 DOI: 10.1083/Jcb.86.3.701  0.743
1980 Emr SD, Hedgpeth J, Clément JM, Silhavy TJ, Hofnung M. Sequence analysis of mutations that prevent export of lambda receptor, an Escherichia coli outer membrane protein. Nature. 285: 82-5. PMID 6445509 DOI: 10.1038/285082A0  0.719
1978 Emr SD, Schwartz M, Silhavy TJ. Mutations altering the cellular localization of the phage lambda receptor, an Escherichia coli outer membrane protein. Proceedings of the National Academy of Sciences of the United States of America. 75: 5802-6. PMID 104291 DOI: 10.1073/Pnas.75.12.5802  0.718
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