Louise N. Johnson - Related publications

Affiliations: 
Molecular Biophysics University of Oxford, Oxford, United Kingdom 
Area:
x-ray crystallography
Website:
http://www.bioch.ox.ac.uk/aspsite/index.asp?pageid=939
NOTE: We are testing a new system for identifying relevant work based on semantic analysis that identifies similarities between recently published papers and the current author's publications. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches.
50 most relevant papers in past 60 days:
Year Citation  Score
2021 Wang Y, Hanrahan G, Azar FA, Mittermaier A. Binding interactions in a kinase active site modulate background ATP hydrolysis. Biochimica Et Biophysica Acta. Proteins and Proteomics. 140720. PMID 34597835 DOI: 10.1016/j.bbapap.2021.140720   
2021 Bandyopadhyay A, Saxena AK. Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system. International Journal of Biological Macromolecules. PMID 34428493 DOI: 10.1016/j.ijbiomac.2021.08.130   
2021 Weiss AKH, Wurzer R, Klapec P, Eder MP, Loeffler JR, von Grafenstein S, Monteleone S, Liedl KR, Jansen-Dürr P, Gstach H. Inhibitors of Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1). Molecules (Basel, Switzerland). 26. PMID 34443596 DOI: 10.3390/molecules26165009   
2021 Ghosh RK, Hilario E, Liu V, Wang Y, Niks D, Holmes JB, Sakhrani VV, Mueller LJ, Dunn MF. Mutation of βGln114 to Ala Alters the Stabilities of Allosteric States in Tryptophan Synthase Catalysis. Biochemistry. PMID 34595921 DOI: 10.1021/acs.biochem.1c00383   
2021 Kang JM, Lê HG, Na BK, Yoo WG. pH-Dependent Structural Dynamics of Cathepsin D-Family Aspartic Peptidase of . Pathogens (Basel, Switzerland). 10. PMID 34578162 DOI: 10.3390/pathogens10091128   
2021 Kim S, Kim KJ. Crystal structure and molecular mechanism of phosphotransbutyrylase from . Journal of Microbiology and Biotechnology. 31: 1-9. PMID 34584034 DOI: 10.4014/jmb.2109.09036   
2021 Gao X, Wu M, Zhang W, Li C, Guo RT, Dai Y, Liu W, Mao S, Lu F, Qin HM. Structural Basis of Salicylic Acid Decarboxylase Reveals a Unique Substrate Recognition Mode and Access Channel. Journal of Agricultural and Food Chemistry. PMID 34553918 DOI: 10.1021/acs.jafc.1c04091   
2021 Dai L, Chang Z, Yang J, Liu W, Yang Y, Chen CC, Zhang L, Huang JW, Sun Y, Guo RT. Structural investigation of a thermostable 1,2-β-mannobiose phosphorylase from Thermoanaerobacter sp. X-514. Biochemical and Biophysical Research Communications. 579: 54-61. PMID 34587555 DOI: 10.1016/j.bbrc.2021.09.046   
2021 Chan PWY, Chakrabarti N, Ing C, Halgas O, To TKW, Wälti M, Petit AP, Tran C, Savchenko A, Yakunin AF, Edwards EA, Pomès R, Pai EF. Defluorination Capability of l-2-Haloacid Dehalogenases in the HAD-like Hydrolase Superfamily Correlates with Active Site Compactness. Chembiochem : a European Journal of Chemical Biology. PMID 34643018 DOI: 10.1002/cbic.202100414   
2021 Currie MJ, Manjunath L, Horne CR, Rendle PM, Subramanian R, Friemann R, Fairbanks AJ, Muscroft-Taylor AC, North RA, Dobson RCJ. N-Acetylmannosamine-6-phosphate 2-epimerase uses a novel substrate-assisted mechanism to catalyze amino sugar epimerization. The Journal of Biological Chemistry. 101113. PMID 34437902 DOI: 10.1016/j.jbc.2021.101113   
2021 Marshall SA, Payne KAP, Fisher K, Titchiner GR, Levy C, Hay S, Leys D. UbiD domain dynamics underpins aromatic decarboxylation. Nature Communications. 12: 5065. PMID 34417452 DOI: 10.1038/s41467-021-25278-z   
2021 Padavattan S, Jos S, Gogoi H, Bagautdinov B. Crystal structure of enoyl-CoA hydratase from Thermus thermophilus HB8. Acta Crystallographica. Section F, Structural Biology Communications. 77: 148-155. PMID 33949975 DOI: 10.1107/S2053230X21004593   
2021 Waidha K, Zurgil U, Ben-Zeev E, Gopas J, Rajendran S, Golan-Goldhirsh A. Inhibition of Cysteine Proteases by 6,6'-Dihydroxythiobinupharidine (DTBN) from . Molecules (Basel, Switzerland). 26. PMID 34443335 DOI: 10.3390/molecules26164743   
2021 Sartor P, Denkhaus L, Gerhardt S, Einsle O, Fetzner S. Structural basis of O-methylation of (2-heptyl-)1-hydroxyquinolin-4(1H)-one and related compounds by the heterocyclic toxin methyltransferase Rv0560c of Mycobacterium tuberculosis. Journal of Structural Biology. 107794. PMID 34506908 DOI: 10.1016/j.jsb.2021.107794   
2021 Darrouzet E, Rinaldi C, Zambelli B, Ciurli S, Cavazza C. Revisiting the CooJ family, a potential chaperone for nickel delivery to [NiFe]‑carbon monoxide dehydrogenase. Journal of Inorganic Biochemistry. 225: 111588. PMID 34530332 DOI: 10.1016/j.jinorgbio.2021.111588   
2021 Singh A, Fenwick RB, Dyson HJ, Wright PE. Role of Active Site Loop Dynamics in Mediating Ligand Release from Dihydrofolate Reductase. Biochemistry. PMID 34428034 DOI: 10.1021/acs.biochem.1c00461   
2021 Song L, Merceron R, Hulpia F, Lucía A, Gracia B, Jian Y, Risseeuw MDP, Verstraelen T, Cos P, Aínsa JA, Boshoff HI, Munier-Lehmann H, Savvides SN, Van Calenbergh S. Structure-aided optimization of non-nucleoside M. tuberculosis thymidylate kinase inhibitors. European Journal of Medicinal Chemistry. 225: 113784. PMID 34450493 DOI: 10.1016/j.ejmech.2021.113784   
2021 Jia Q, Zeng H, Li H, Xiao N, Tang J, Gao S, Zhang J, Xie W. The C-terminal loop of guanosine deaminase is essential to catalysis. Chemical Communications (Cambridge, England). PMID 34477187 DOI: 10.1039/d1cc03042f   
2021 Gabrielli V, Muñoz-García JC, Pergolizzi G, de Andrade P, Khimyak Y, Field RA, Angulo J. Molecular recognition of natural and non-natural substrates by cellodextrin phosphorylase from Ruminiclostridium thermocellum investigated by NMR spectroscopy. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 34436794 DOI: 10.1002/chem.202102039   
2021 Mota C, Diniz A, Coelho C, Santos-Silva T, Esmaeeli M, Leimkühler S, Cabrita EJ, Marcelo F, Romão MJ. Interrogating the Inhibition Mechanisms of Human Aldehyde Oxidase by X-ray Crystallography and NMR Spectroscopy: The Raloxifene Case. Journal of Medicinal Chemistry. PMID 34415167 DOI: 10.1021/acs.jmedchem.1c01125   
2021 Chakraborty K, Dhara S. Conoidecyclics A-C from marine macroalga Turbinaria conoides: Newly described natural macrolides with prospective bioactive properties. Phytochemistry. 191: 112909. PMID 34419665 DOI: 10.1016/j.phytochem.2021.112909   
2021 Wander R, Kaminski AM, Xu Y, Pagadala V, Krahn JM, Pham TQ, Liu J, Pedersen LC. Deciphering the substrate recognition mechanisms of the heparan sulfate 3--sulfotransferase-3. Rsc Chemical Biology. 2: 1239-1248. PMID 34458837 DOI: 10.1039/d1cb00079a   
2021 Ghosh AK, Raghavaiah J, Shahabi D, Yadav M, Anson BJ, Lendy EK, Hattori SI, Higashi-Kuwata N, Mitsuya H, Mesecar AD. Indole Chloropyridinyl Ester-Derived SARS-CoV-2 3CLpro Inhibitors: Enzyme Inhibition, Antiviral Efficacy, Structure-Activity Relationship, and X-ray Structural Studies. Journal of Medicinal Chemistry. PMID 34528437 DOI: 10.1021/acs.jmedchem.1c01214   
2021 Mohamed WI, Park SL, Rabl J, Leitner A, Boehringer D, Peter M. The human GID complex engages two independent modules for substrate recruitment. Embo Reports. e52981. PMID 34647674 DOI: 10.15252/embr.202152981   
2021 Chen Y, Jia H, Zhang J, Liang Y, Liu R, Zhang Q, Bartlam M. Structure and mechanism of the γ-glutamyl-γ-aminobutyrate hydrolase SpuA from Pseudomonas aeruginosa. Acta Crystallographica. Section D, Structural Biology. 77: 1305-1316. PMID 34605433 DOI: 10.1107/S2059798321008986   
2021 Chan SI, Chang WH, Huang SH, Lin HH, Yu SS. Catalytic machinery of methane oxidation in particulate methane monooxygenase (pMMO). Journal of Inorganic Biochemistry. 225: 111602. PMID 34547604 DOI: 10.1016/j.jinorgbio.2021.111602   
2021 Chen C, Han X, Liu W, Ma L, Liu K, Guo RT. [Structure-based engineering of PET hydrolase from Ideonella sakaiensis]. Sheng Wu Gong Cheng Xue Bao = Chinese Journal of Biotechnology. 37: 3268-3275. PMID 34622634 DOI: 10.13345/j.cjb.200632   
2021 Guo J, Wang Y, Zhang X, Gao W, Cai Z, Hong T, Man Z, Qing Q. Improvement of the Catalytic Activity of Chitosanase BsCsn46A from by Site-Saturation Mutagenesis of Proline121. Journal of Agricultural and Food Chemistry. PMID 34590486 DOI: 10.1021/acs.jafc.1c04206   
2021 DeLaney C, Sheng Y, Pectol DC, Vantansever E, Zhang H, Bhuvanesh N, Salas I, Liu WR, Fierke CF, Darensbourg MY. Zinc thiotropolone combinations as inhibitors of the SARS-CoV-2 main protease. Dalton Transactions (Cambridge, England : 2003). PMID 34396374 DOI: 10.1039/d1dt02499j   
2021 Korasick DA, Christgen SL, Qureshi IA, Becker DF, Tanner JJ. Probing the function of a ligand-modulated dynamic tunnel in bifunctional proline utilization A (PutA). Archives of Biochemistry and Biophysics. 109025. PMID 34506758 DOI: 10.1016/j.abb.2021.109025   
2021 Ferretti MV, Hussien RA, Ballicora MA, Iglesias AA, Figueroa CM, Asencion Diez MD. The ADP-glucose pyrophosphorylase from Melainabacteria: A comparative study between photosynthetic and non-photosynthetic bacterial sources. Biochimie. PMID 34560201 DOI: 10.1016/j.biochi.2021.09.011   
2021 Veldman W, Liberato MV, Souza VP, Almeida VM, Marana SR, Tastan Bishop Ö, Polikarpov I. Differences in Gluco and Galacto Substrate-Binding Interactions in a Dual 6Pβ-Glucosidase/6Pβ-Galactosidase Glycoside Hydrolase 1 Enzyme from . Journal of Chemical Information and Modeling. PMID 34423980 DOI: 10.1021/acs.jcim.1c00413   
2021 Scaletti E, Huschmann FU, Mueller U, Weiss MS, Sträter N. Substrate binding modes of purine and pyrimidine nucleotides to human ecto-5'-nucleotidase (CD73) and inhibition by their bisphosphonic acid derivatives. Purinergic Signalling. PMID 34403084 DOI: 10.1007/s11302-021-09802-w   
2021 Kummer MJ, Lee YS, Yuan M, Alkotaini B, Zhao J, Blumenthal E, Minteer SD. Substrate Channeling by a Rationally Designed Fusion Protein in a Biocatalytic Cascade. Jacs Au. 1: 1187-1197. PMID 34467357 DOI: 10.1021/jacsau.1c00180   
2021 Mori T, Zhai R, Ushimaru R, Matsuda Y, Abe I. Molecular insights into the endoperoxide formation by Fe(II)/α-KG-dependent oxygenase NvfI. Nature Communications. 12: 4417. PMID 34285212 DOI: 10.1038/s41467-021-24685-6   
2021 Carr SC, Torres MA, Morris JS, Facchini PJ, Ng KKS. Structural studies of codeinone reductase reveal novel insights into aldo-keto reductase function in benzylisoquinoline alkaloid biosynthesis. The Journal of Biological Chemistry. 101211. PMID 34547292 DOI: 10.1016/j.jbc.2021.101211   
2021 Cheng F, Zhai QY, Gao XF, Liu HT, Qiu S, Wang YJ, Zheng YG. Tuning enzymatic properties by protein engineering toward catalytic tetrad of carbonyl reductase. Biotechnology and Bioengineering. PMID 34436762 DOI: 10.1002/bit.27925   
2021 Wang Y, Mittermaier AK. Characterizing Bi-substrate Enzyme Kinetics at High Resolution by 2D-ITC. Analytical Chemistry. PMID 34514786 DOI: 10.1021/acs.analchem.1c02705   
2021 Pawara R, Ahmad I, Surana S, Patel H. Computational identification of 2,4-disubstituted amino-pyrimidines as L858R/T790M-EGFR double mutant inhibitors using pharmacophore mapping, molecular docking, binding free energy calculation, DFT study and molecular dynamic simulation. In Silico Pharmacology. 9: 54. PMID 34631361 DOI: 10.1007/s40203-021-00113-x   
2021 Cui J, Jia J. Discovery of juglone and its derivatives as potent SARS-CoV-2 main proteinase inhibitors. European Journal of Medicinal Chemistry. 225: 113789. PMID 34438124 DOI: 10.1016/j.ejmech.2021.113789   
2021 Hu R, Cui R, Tang Q, Lan D, Wang F, Wang Y. Enhancement of Phospholipid Binding and Catalytic Efficiency of Phospholipase D by Increasing Hydrophobicity of the Active Site Loop. Journal of Agricultural and Food Chemistry. PMID 34516129 DOI: 10.1021/acs.jafc.1c04078   
2021 Alves Feliciano C, Eckenroth BE, Diaz OR, Doublié S, Shen A. A lipoprotein allosterically activates the CwlD amidase during Clostridioides difficile spore formation. Plos Genetics. 17: e1009791. PMID 34570752 DOI: 10.1371/journal.pgen.1009791   
2021 Bakunova AK, Nikolaeva AY, Rakitina TV, Isaikina TY, Khrenova MG, Boyko KM, Popov VO, Bezsudnova EY. The Uncommon Active Site of D-Amino Acid Transaminase from : Biochemical and Structural Insights into the New Enzyme. Molecules (Basel, Switzerland). 26. PMID 34443642 DOI: 10.3390/molecules26165053   
2021 Campbell AC, Prater AR, Bogner AN, Quinn TP, Gates KS, Becker DF, Tanner JJ. Photoinduced Covalent Irreversible Inactivation of Proline Dehydrogenase by S-Heterocycles. Acs Chemical Biology. PMID 34542291 DOI: 10.1021/acschembio.1c00427   
2021 Lee R, Kim V, Chun Y, Kim D. Structure-Functional Analysis of Human Cytochrome P450 2C8 Using Directed Evolution. Pharmaceutics. 13. PMID 34575505 DOI: 10.3390/pharmaceutics13091429   
2021 Gentile K, Bhide A, Kauffman J, Ghosh S, Maiti S, Adair J, Lee TH, Sen A. Enzyme aggregation and fragmentation induced by catalysis relevant species. Physical Chemistry Chemical Physics : Pccp. PMID 34516596 DOI: 10.1039/d1cp02966e   
2021 Guo Y, Li DF, Zheng J, Xu Y, Zhou NY. Single-component and two-component -nitrophenol monooxygenases: structural basis for their catalytic difference. Applied and Environmental Microbiology. AEM0117121. PMID 34469195 DOI: 10.1128/AEM.01171-21   
2021 Prasher P, Sharma M. Medicinal chemistry of pyrophosphate mimics: A mini review. Drug Development Research. PMID 34506652 DOI: 10.1002/ddr.21877   
2021 Tsai WC, Aleem AM, Tena J, Rivera-Velazquez M, Brah HS, Tripathi S, D'silva M, Nadler JL, Kalyanaraman C, Jacobson MP, Holman T. Docking and mutagenesis studies lead to improved inhibitor development of ML355 for human platelet 12-lipoxygenase. Bioorganic & Medicinal Chemistry. 46: 116347. PMID 34507163 DOI: 10.1016/j.bmc.2021.116347   
2021 Yildiz I. Computational Analysis of the Nicotine Oxidoreductase Mechanism by the ONIOM Method. Acs Omega. 6: 22422-22428. PMID 34497931 DOI: 10.1021/acsomega.1c03357