Matthew R. Pratt - Publications

University of Southern California, Los Angeles, CA, United States 
Chemical Biology

70 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Balana AT, Levine PM, Craven TW, Mukherjee S, Pedowitz NJ, Moon SP, Takahashi TT, Becker CFW, Baker D, Pratt MR. O-GlcNAc modification of small heat shock proteins enhances their anti-amyloid chaperone activity. Nature Chemistry. PMID 33723378 DOI: 10.1038/s41557-021-00648-8  1
2021 Balana AT, Moon SP, Pratt MR. O-GlcNAcylated peptides and proteins for structural and functional studies. Current Opinion in Structural Biology. 68: 84-93. PMID 33434850 DOI: 10.1016/  1
2021 Galesic A, Rakshit A, Cutolo G, Pacheco RP, Balana AT, Moon SP, Pratt MR. Comparison of -Acetyl-Glucosamine to Other Monosaccharides Reveals Structural Differences for the Inhibition of α-Synuclein Aggregation. Acs Chemical Biology. PMID 33399442 DOI: 10.1021/acschembio.0c00716  1
2020 Pedowitz NJ, Batt AR, Darabedian N, Pratt MR. MYPT1 O-GlcNAc modification regulates sphingosine-1-phosphate mediated contraction. Nature Chemical Biology. PMID 32929277 DOI: 10.1038/s41589-020-0640-8  1
2020 Jin S, Brea RJ, Rudd AK, Moon SP, Pratt MR, Devaraj NK. Traceless native chemical ligation of lipid-modified peptide surfactants by mixed micelle formation. Nature Communications. 11: 2793. PMID 32493905 DOI: 10.1038/s41467-020-16595-w  0.36
2020 Darabedian N, Yang B, Ding R, Cutolo G, Zaro BW, Woo CM, Pratt MR. O-Acetylated Chemical Reporters of Glycosylation Can Display Metabolism-Dependent Background Labeling of Proteins but Are Generally Reliable Tools for the Identification of Glycoproteins. Frontiers in Chemistry. 8: 318. PMID 32411667 DOI: 10.3389/fchem.2020.00318  1
2020 Pedowitz NJ, Zaro BW, Pratt MR. Metabolic Labeling for the Visualization and Identification of Potentially O-GlcNAc-Modified Proteins. Current Protocols in Chemical Biology. 12: e81. PMID 32289208 DOI: 10.1002/cpch.81  1
2020 Galesic A, Pratt MR. Investigating the Effects of O-GlcNAc Modifications in Parkinson's Disease Using Semisynthetic α-Synuclein. Methods in Molecular Biology (Clifton, N.J.). 2133: 313-326. PMID 32144674 DOI: 10.1007/978-1-0716-0434-2_15  1
2020 Yang X, Forster ER, Darabedian N, Kim AT, Pratt MR, Shen A, Hang HC. Translation of microbiota short-chain fatty acid mechanisms affords anti-infective acyl-salicylic acid derivatives. Acs Chemical Biology. PMID 32091869 DOI: 10.1021/acschembio.9b01009  1
2019 Moon SP, Balana AT, Galesic A, Rakshit A, Pratt MR. Ubiquitination can change the structure of the α-synuclein amyloid fiber in a site selective fashion. The Journal of Organic Chemistry. PMID 31809571 DOI: 10.1021/acs.joc.9b02641  1
2019 Walter LA, Lin YH, Halbrook CJ, Chuh KN, He L, Pedowitz NJ, Batt AR, Brennan CK, Stiles BL, Lyssiotis CA, Pratt MR. Inhibiting the hexosamine biosynthetic pathway lowers O-GlcNAcylation levels and sensitizes cancer to environmental stress. Biochemistry. PMID 31625393 DOI: 10.1021/acs.biochem.9b00560  1
2019 Levine PM, Balana AJ, Sturchler E, Koole C, Noda H, Zarzycka B, Daley EJ, Truong TT, Katritch V, Gardella TJ, Wootten D, Sexton PM, McDonald P, Pratt MR. O-GlcNAc engineering of GPCR peptide-agonists improves their stability and in vivo activity. Journal of the American Chemical Society. PMID 31418572 DOI: 10.1021/jacs.9b05365  1
2019 Darabedian N, Pratt MR. Identifying potentially O-GlcNAcylated proteins using metabolic labeling, bioorthogonal enrichment, and Western blotting. Methods in Enzymology. 622: 293-307. PMID 31155058 DOI: 10.1016/bs.mie.2019.02.017  1
2019 Levine PM, Galesic A, Balana AT, Mahul-Mellier AL, Navarro MX, De Leon CA, Lashuel HA, Pratt MR. α-Synuclein O-GlcNAcylation alters aggregation and toxicity, revealing certain residues as potential inhibitors of Parkinson's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 30651314 DOI: 10.1073/pnas.1808845116  1
2018 Darabedian N, Chen T, Molina H, Pratt MR, Schonthal AH. Bioorthogonal profiling of a cancer cell proteome identifies a large set of 3-bromopyruvate targets beyond glycolysis. Acs Chemical Biology. PMID 30395437 DOI: 10.1021/acschembio.8b00743  1
2018 Gilormini PA, Batt AR, Pratt MR, Biot C. Asking more from metabolic oligosaccharide engineering. Chemical Science. 9: 7585-7595. PMID 30393518 DOI: 10.1039/c8sc02241k  1
2018 Darabedian N, Thompson J, Chuh KN, Hsieh-Wilson LC, Pratt MR. Optimization of chemoenzymatic mass-tagging by strain-promoted cycloaddition (SPAAC) for the determination of O-GlcNAc stoichiometry by Western blotting. Biochemistry. PMID 30169966 DOI: 10.1021/acs.biochem.8b00648  1
2018 De Leon CA, Lang G, Saavedra MI, Pratt MR. Simple and Efficient Preparation of O- and S-GlcNAcylated Amino Acids through InBr-Catalyzed Synthesis of β- N-Acetylglycosides from Commercially Available Reagents. Organic Letters. PMID 30088936 DOI: 10.1021/acs.orglett.8b02182  1
2018 Walter LA, Batt AR, Darabedian N, Zaro BW, Pratt MR. Azide- and alkyne-bearing metabolic chemical reporters of glycosylation show structure-dependent feedback inhibition of the hexosamine biosynthetic pathway. Chembiochem : a European Journal of Chemical Biology. PMID 29979493 DOI: 10.1002/cbic.201800280  1
2018 Darabedian N, Gao J, Chuh KN, Woo CM, Pratt MR. The metabolic chemical reporter 6-azido-6-deoxy-glucose further reveals the substrate promiscuity of O-GlcNAc transferase and catalyzes the discovery of intracellular protein modification by O-glucose. Journal of the American Chemical Society. PMID 29771506 DOI: 10.1021/jacs.7b13488  1
2018 Bateman LA, Zaro BW, Miller SM, Pratt MR. Correction to "An Alkyne-Aspirin Chemical Reporter for the Detection of Aspirin-Dependent Protein Modification in Living Cells". Journal of the American Chemical Society. PMID 29589917 DOI: 10.1021/jacs.8b03225  1
2018 Levine PM, Pratt MR. Revolutionizing Our Understanding of Amyloidogenic Proteins by Cryo-Electron Microscopy. Biochemistry. PMID 29323876 DOI: 10.1021/acs.biochem.7b01084  1
2017 De Leon CA, Levine PM, Craven TW, Pratt MR. The sulfur-linked analog of O-GlcNAc (S-GlcNAc) is an enzymatically stable and a reasonable structural-surrogate for O-GlcNAc at the peptide and protein levels. Biochemistry. PMID 28627871 DOI: 10.1021/acs.biochem.7b00268  1
2017 Chuh KN, Batt AR, Zaro BW, Darabedian N, Marotta NP, Brennan CK, Amirhekmat A, Pratt MR. The New Chemical Reporter 6-Alkynyl-6-deoxy-GlcNAc Reveals O-GlcNAc Modification of the Apoptotic Caspases That Can Block the Cleavage/Activation of Caspase-8. Journal of the American Chemical Society. PMID 28528544 DOI: 10.1021/jacs.7b02213  1
2017 Levine PM, De Leon CA, Galesic A, Balana A, Marotta NP, Lewis YE, Pratt MR. O-GlcNAc modification inhibits the calpain-mediated cleavage of α-synuclein. Bioorganic & Medicinal Chemistry. PMID 28487126 DOI: 10.1016/j.bmc.2017.04.038  1
2017 Batt AR, Zaro BW, Navarro MX, Pratt MR. Metabolic chemical reporters of glycans exhibit cell-type selective metabolism and glycoprotein labeling. Chembiochem : a European Journal of Chemical Biology. PMID 28231413 DOI: 10.1002/cbic.201700020  1
2017 Lewis YE, Galesic A, Levine PM, De Leon CA, Lamiri N, Brennan CK, Pratt MR. O-GlcNAcylation of α-synuclein at serine 87 reduces aggregation without affecting membrane binding. Acs Chemical Biology. PMID 28195695 DOI: 10.1021/acschembio.7b00113  1
2017 Zaro BW, Batt AR, Chuh KN, Navarro MX, Pratt MR. The Small Molecule 2-Azido-2-deoxy-glucose Is a Metabolic Chemical Reporter of O-GlcNAc Modifications in Mammalian Cells, Revealing an Unexpected Promiscuity of O-GlcNAc Transferase. Acs Chemical Biology. PMID 28135057 DOI: 10.1021/acschembio.6b00877  1
2016 Chuh KN, Batt AR, Pratt MR. Chemical Methods for Encoding and Decoding of Posttranslational Modifications. Cell Chemical Biology. 23: 86-107. PMID 26933738 DOI: 10.1016/j.chembiol.2015.11.006  1
2016 Lewis YE, Abeywardana T, Lin YH, Galesic A, Pratt MR. Synthesis of a Bis-thio-acetone (BTA) Analog of the Lysine Isopeptide Bond and its Application to Investigate the effects of Ubiquitination and SUMOylation on α-Synuclein Aggregation and Toxicity. Acs Chemical Biology. PMID 26726734 DOI: 10.1021/acschembio.5b01042  1
2015 Marotta NP, Lin YH, Lewis YE, Ambroso MR, Zaro BW, Roth MT, Arnold DB, Langen R, Pratt MR. O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease. Nature Chemistry. 7: 913-20. PMID 26492012 DOI: 10.1038/nchem.2361  1
2015 Pratt MR, Abeywardana T, Marotta NP. Synthetic Proteins and Peptides for the Direct Interrogation of α-Synuclein Posttranslational Modifications. Biomolecules. 5: 1210-27. PMID 26120904 DOI: 10.3390/biom5031210  1
2015 Chuh KN, Pratt MR. Chemistry-enabled methods for the visualization of cell-surface glycoproteins in Metazoans. Glycoconjugate Journal. PMID 25913724 DOI: 10.1007/s10719-015-9589-3  1
2015 Abeywardana T, Pratt MR. Extent of inhibition of α-synuclein aggregation in vitro by SUMOylation is conjugation site- and SUMO isoform-selective. Biochemistry. 54: 959-61. PMID 25607946 DOI: 10.1021/bi501512m  1
2015 Chuh KN, Pratt MR. Chemical methods for the proteome-wide identification of posttranslationally modified proteins. Current Opinion in Chemical Biology. 24: 27-37. PMID 25461721 DOI: 10.1016/j.cbpa.2014.10.020  1
2014 Chesarino NM, Hach JC, Chen JL, Zaro BW, Rajaram MV, Turner J, Schlesinger LS, Pratt MR, Hang HC, Yount JS. Chemoproteomics reveals Toll-like receptor fatty acylation. Bmc Biology. 12: 91. PMID 25371237 DOI: 10.1186/s12915-014-0091-3  1
2014 Chuh KN, Zaro BW, Piller F, Piller V, Pratt MR. Changes in metabolic chemical reporter structure yield a selective probe of O-GlcNAc modification. Journal of the American Chemical Society. 136: 12283-95. PMID 25153642 DOI: 10.1021/ja504063c  1
2014 Zaro BW, Chuh KN, Pratt MR. Chemical reporter for visualizing metabolic cross-talk between carbohydrate metabolism and protein modification. Acs Chemical Biology. 9: 1991-6. PMID 25062036 DOI: 10.1021/cb5005564  1
2014 Abeywardana T, Pratt MR. Using chemistry to investigate the molecular consequences of protein ubiquitylation. Chembiochem : a European Journal of Chemical Biology. 15: 1547-54. PMID 24976261 DOI: 10.1002/cbic.201402117  1
2014 Gurel Z, Zaro BW, Pratt MR, Sheibani N. Identification of O-GlcNAc modification targets in mouse retinal pericytes: implication of p53 in pathogenesis of diabetic retinopathy. Plos One. 9: e95561. PMID 24788674 DOI: 10.1371/journal.pone.0095561  1
2014 Lin YH, Pratt MR. A dual small-molecule rheostat for precise control of protein concentration in Mammalian cells. Chembiochem : a European Journal of Chemical Biology. 15: 805-9. PMID 24615791 DOI: 10.1002/cbic.201400006  1
2013 Abeywardana T, Lin YH, Rott R, Engelender S, Pratt MR. Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein. Chemistry & Biology. 20: 1207-13. PMID 24210006 DOI: 10.1016/j.chembiol.2013.09.009  1
2013 Bateman LA, Zaro BW, Miller SM, Pratt MR. An alkyne-aspirin chemical reporter for the detection of aspirin-dependent protein modification in living cells. Journal of the American Chemical Society. 135: 14568-73. PMID 23998633 DOI: 10.1021/ja408322b  1
2013 Zaro BW, Hang HC, Pratt MR. Incorporation of unnatural sugars for the identification of glycoproteins. Methods in Molecular Biology (Clifton, N.J.). 951: 57-67. PMID 23296524 DOI: 10.1007/978-1-62703-146-2_5  1
2013 Bateman LA, Zaro BW, Chuh KN, Pratt MR. N-Propargyloxycarbamate monosaccharides as metabolic chemical reporters of carbohydrate salvage pathways and protein glycosylation. Chemical Communications (Cambridge, England). 49: 4328-30. PMID 23235740 DOI: 10.1039/c2cc37963e  1
2013 Hang HC, Pratt MR. Molecular Probes for Protein Glycosylation Reference Module in Chemistry, Molecular Sciences and Chemical Engineering. DOI: 10.1016/B978-0-12-409547-2.02835-3  1
2012 Marotta NP, Cherwien CA, Abeywardana T, Pratt MR. O-GlcNAc modification prevents peptide-dependent acceleration of α-synuclein aggregation. Chembiochem : a European Journal of Chemical Biology. 13: 2665-70. PMID 23143740 DOI: 10.1002/cbic.201200478  1
2012 Pratt MR. Small-molecule reprogramming of cancer metabolism. Chemistry & Biology. 19: 1084-5. PMID 22999876 DOI: 10.1016/j.chembiol.2012.09.001  1
2012 Meier F, Abeywardana T, Dhall A, Marotta NP, Varkey J, Langen R, Chatterjee C, Pratt MR. Semisynthetic, site-specific ubiquitin modification of α-synuclein reveals differential effects on aggregation. Journal of the American Chemical Society. 134: 5468-71. PMID 22404520 DOI: 10.1021/ja300094r  1
2011 Zaro BW, Yang YY, Hang HC, Pratt MR. Chemical reporters for fluorescent detection and identification of O-GlcNAc-modified proteins reveal glycosylation of the ubiquitin ligase NEDD4-1 Proceedings of the National Academy of Sciences of the United States of America. 108: 8146-8151. PMID 21540332 DOI: 10.1073/pnas.1102458108  1
2011 Zaro BW, Bateman LA, Pratt MR. Robust in-gel fluorescence detection of mucin-type O-linked glycosylation Bioorganic and Medicinal Chemistry Letters. 21: 5062-5066. PMID 21531554 DOI: 10.1016/j.bmcl.2011.04.038  1
2010 Lau HD, Yaegashi J, Zaro BW, Pratt MR. Precise control of protein concentration in living cells. Angewandte Chemie (International Ed. in English). 49: 8458-61. PMID 20878685 DOI: 10.1002/anie.201003073  1
2009 Averette KM, Pratt MR, Yang Y, Bassilian S, Whitelegge JP, Loo JA, Muir TW, Bradley KA. Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent. Plos One. 4: e7913. PMID 19924255 DOI: 10.1371/journal.pone.0007913  1
2009 McGinty RK, Köhn M, Chatterjee C, Chiang KP, Pratt MR, Muir TW. Structure-activity analysis of semisynthetic nucleosomes: mechanistic insights into the stimulation of Dot1L by ubiquitylated histone H2B. Acs Chemical Biology. 4: 958-68. PMID 19799466 DOI: 10.1021/cb9002255  1
2009 Pratt MR, Sekedat MD, Chiang KP, Muir TW. Direct measurement of cathepsin B activity in the cytosol of apoptotic cells by an activity-based probe. Chemistry & Biology. 16: 1001-12. PMID 19778728 DOI: 10.1016/j.chembiol.2009.07.011  1
2008 Schwartz EC, Shekhtman A, Dutta K, Pratt MR, Cowburn D, Darst S, Muir TW. A full-length group 1 bacterial sigma factor adopts a compact structure incompatible with DNA binding. Chemistry & Biology. 15: 1091-103. PMID 18940669 DOI: 10.1016/j.chembiol.2008.09.008  1
2008 Pratt MR, Muir TW. Synthesis of Large Biological Molecules: Expressed Protein Ligation Chemical Biology: From Small Molecules to Systems Biology and Drug Design, Volume 1-3. 2: 537-566. DOI: 10.1002/9783527619375.ch10a  1
2007 Vila-Perelló M, Pratt MR, Tulin F, Muir TW. Covalent capture of phospho-dependent protein oligomerization by site-specific incorporation of a diazirine photo-cross-linker. Journal of the American Chemical Society. 129: 8068-9. PMID 17567014 DOI: 10.1021/ja072013j  1
2007 Pratt MR, Schwartz EC, Muir TW. Small-molecule-mediated rescue of protein function by an inducible proteolytic shunt. Proceedings of the National Academy of Sciences of the United States of America. 104: 11209-14. PMID 17563385 DOI: 10.1073/pnas.0700816104  1
2005 Pratt MR, Bertozzi CR. Synthetic glycopeptides and glycoproteins as tools for biology. Chemical Society Reviews. 34: 58-68. PMID 15643490 DOI: 10.1039/b400593g  1
2004 Pratt MR, Hang HC, Ten Hagen KG, Rarick J, Gerken TA, Tabak LA, Bertozzi CR. Deconvoluting the functions of polypeptide N-alpha-acetylgalactosaminyltransferase family members by glycopeptide substrate profiling. Chemistry & Biology. 11: 1009-16. PMID 15271359 DOI: 10.1016/j.chembiol.2004.05.009  1
2004 Mougous JD, Petzold CJ, Senaratne RH, Lee DH, Akey DL, Lin FL, Munchel SE, Pratt MR, Riley LW, Leary JA, Berger JM, Bertozzi CR. Identification, function and structure of the mycobacterial sulfotransferase that initiates sulfolipid-1 biosynthesis. Nature Structural & Molecular Biology. 11: 721-9. PMID 15258569 DOI: 10.1038/nsmb802  1
2004 Pratt MR, Bertozzi CR. Syntheses of 6-sulfo sialyl Lewis X glycans corresponding to the L-selectin ligand "sulfoadhesin". Organic Letters. 6: 2345-8. PMID 15228275 DOI: 10.1021/ol0493195  1
2004 Woodruff PJ, Carlson BL, Siridechadilok B, Pratt MR, Senaratne RH, Mougous JD, Riley LW, Williams SJ, Bertozzi CR. Trehalose is required for growth of Mycobacterium smegmatis. The Journal of Biological Chemistry. 279: 28835-43. PMID 15102847 DOI: 10.1074/jbc.M313103200  1
2004 Hang HC, Yu C, Pratt MR, Bertozzi CR. Probing glycosyltransferase activities with the Staudinger ligation. Journal of the American Chemical Society. 126: 6-7. PMID 14709032 DOI: 10.1021/ja037692m  1
2003 Pratt MR, Leigh CD, Bertozzi CR. Formation of 1,1-alpha,alpha-glycosidic bonds by intramolecular aglycone delivery. A convergent synthesis of trehalose. Organic Letters. 5: 3185-8. PMID 12943383 DOI: 10.1021/ol034836t  1
2003 Pratt MR, Bertozzi CR. Chemoselective ligation applied to the synthesis of a biantennary N-linked glycoform of CD52. Journal of the American Chemical Society. 125: 6149-59. PMID 12785846 DOI: 10.1021/ja029346v  1
2003 Marcaurelle LA, Pratt MR, Bertozzi CR. Synthesis of thioether-linked analogues of the 2,3-sialyl-TF and MECA-79 antigens: mucin-type glycopeptides associated with cancer and inflammation. Chembiochem : a European Journal of Chemical Biology. 4: 224-8. PMID 12616638 DOI: 10.1002/cbic.200390036  1
2002 Grogan MJ, Pratt MR, Marcaurelle LA, Bertozzi CR. Homogeneous glycopeptides and glycoproteins for biological investigation. Annual Review of Biochemistry. 71: 593-634. PMID 12045107 DOI: 10.1146/annurev.biochem.71.110601.135334  1
2001 Mitchell SA, Pratt MR, Hruby VJ, Polt R. Solid-phase synthesis of O-linked glycopeptide analogues of enkephalin Journal of Organic Chemistry. 66: 2327-2342. PMID 11281773 DOI: 10.1021/jo005712m  1
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