Dylan Marchione - Publications

Affiliations: 
2015-2019 University of Pennsylvania School of Medicine, Philadelphia, PA, United States 

22 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Bryant L, Li D, Cox SG, Marchione D, Joiner EF, Wilson K, Janssen K, Lee P, March ME, Nair D, Sherr E, Fregeau B, Wierenga KJ, Wadley A, Mancini GMS, et al. Histone H3.3 beyond cancer: Germline mutations in cause a previously unidentified neurodegenerative disorder in 46 patients. Science Advances. 6. PMID 33268356 DOI: 10.1126/sciadv.abc9207  0.8
2020 Chen CCL, Deshmukh S, Jessa S, Hadjadj D, Lisi V, Andrade AF, Faury D, Jawhar W, Dali R, Suzuki H, Pathania M, A D, Dubois F, Woodward E, Hébert S, ... ... Marchione DM, et al. Histone H3.3G34-Mutant Interneuron Progenitors Co-opt PDGFRA for Gliomagenesis. Cell. PMID 33259802 DOI: 10.1016/j.cell.2020.11.012  0.8
2020 Harutyunyan AS, Chen H, Lu T, Horth C, Nikbakht H, Krug B, Russo C, Bareke E, Marchione DM, Coradin M, Garcia BA, Jabado N, Majewski J. H3K27M in Gliomas Causes a One-Step Decrease in H3K27 Methylation and Reduced Spreading within the Constraints of H3K36 Methylation. Cell Reports. 33: 108390. PMID 33207202 DOI: 10.1016/j.celrep.2020.108390  0.8
2020 Jain SU, Khazaei S, Marchione DM, Lundgren SM, Wang X, Weinberg DN, Deshmukh S, Juretic N, Lu C, Allis CD, Garcia BA, Jabado N, Lewis PW. Histone H3.3 G34 mutations promote aberrant PRC2 activity and drive tumor progression. Proceedings of the National Academy of Sciences of the United States of America. PMID 33067396 DOI: 10.1073/pnas.2006076117  0.8
2020 Khazaei S, De Jay N, Deshmukh S, Hendrikse LD, Jawhar W, Chen CC, Mikael LG, Faury D, Marchione DM, Lanoix J, Bonneil E, Ishii T, Jain SU, Rossokhata K, Sihota TS, et al. H3.3G34W promotes growth and impedes differentiation of osteoblast-like mesenchymal progenitors in Giant Cell Tumour of Bone. Cancer Discovery. PMID 32967858 DOI: 10.1158/2159-8290.CD-20-0461  0.8
2020 Klichinsky M, Ruella M, Shestova O, Lu XM, Best A, Zeeman M, Schmierer M, Gabrusiewicz K, Anderson NR, Petty NE, Cummins KD, Shen F, Shan X, Veliz K, Blouch K, ... ... Marchione DM, et al. Human chimeric antigen receptor macrophages for cancer immunotherapy. Nature Biotechnology. PMID 32361713 DOI: 10.1038/S41587-020-0462-Y  0.8
2020 Marchione DM, Ilieva I, Devins K, Sharpe D, Pappin DJ, Garcia BA, Wilson JP, Wojcik JB. HYPERsol: High-Quality Data from Archival FFPE Tissue for Clinical Proteomics. Journal of Proteome Research. PMID 31935107 DOI: 10.1021/acs.jproteome.9b00686  0.8
2020 Klichinsky M, Ruella M, Shestova O, Best A, Blouch K, Lu XM, Kenderian SS, Kim MY, O'Connor R, Wallace S, Kozlowski M, Marchione DM, Shestov M, Garcia BA, June C, et al. Abstract PR07: Human chimeric antigen receptor (CAR) macrophages for cancer immunotherapy Cancer Immunology Research. 8. DOI: 10.1158/2326-6074.Tumimm18-Pr07  0.8
2019 Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 36: 338-339. PMID 31526762 DOI: 10.1016/j.ccell.2019.08.012  0.8
2019 Weinberg DN, Papillon-Cavanagh S, Chen H, Yue Y, Chen X, Rajagopalan KN, Horth C, McGuire JT, Xu X, Nikbakht H, Lemiesz AE, Marchione DM, Marunde MR, Meiners MJ, Cheek MA, et al. The histone mark H3K36me2 recruits DNMT3A and shapes the intergenic DNA methylation landscape. Nature. PMID 31485078 DOI: 10.1038/S41586-019-1534-3  0.8
2019 Marchione DM, Lisby A, Viaene AN, Santi M, Nasrallah M, Wang LP, Williams EA, Larque AB, Chebib I, Garcia BA, Wojcik JB. Histone H3K27 dimethyl loss is highly specific for malignant peripheral nerve sheath tumor and distinguishes true PRC2 loss from isolated H3K27 trimethyl loss. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. PMID 31175328 DOI: 10.1038/S41379-019-0287-8  0.8
2019 Krug B, De Jay N, Harutyunyan AS, Deshmukh S, Marchione DM, Guilhamon P, Bertrand KC, Mikael LG, McConechy MK, Chen CCL, Khazaei S, Koncar RF, Agnihotri S, Faury D, Ellezam B, et al. Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas. Cancer Cell. 35: 782-797.e8. PMID 31085178 DOI: 10.1016/J.Ccell.2019.04.004  0.8
2019 Wojcik JB, Marchione DM, Sidoli S, Djedid A, Lisby A, Majewski J, Garcia BA. Epigenomic reordering induced by Polycomb loss drives oncogenesis but leads to therapeutic vulnerabilities in malignant peripheral nerve sheath tumors. Cancer Research. PMID 30898839 DOI: 10.1158/0008-5472.Can-18-3704  0.8
2019 Harutyunyan AS, Krug B, Chen H, Papillon-Cavanagh S, Zeinieh M, De Jay N, Deshmukh S, Chen CCL, Belle J, Mikael LG, Marchione DM, Li R, Nikbakht H, Hu B, Cagnone G, et al. H3K27M induces defective chromatin spread of PRC2-mediated repressive H3K27me2/me3 and is essential for glioma tumorigenesis. Nature Communications. 10: 1262. PMID 30890717 DOI: 10.1038/S41467-019-09140-X  0.8
2018 Marchione DM, Garcia BA, Wojcik J. Proteomic approaches for cancer epigenetics research. Expert Review of Proteomics. 1-15. PMID 30482069 DOI: 10.1080/14789450.2019.1550363  0.8
2018 Yuan ZF, Sidoli S, Marchione DM, Simithy J, Janssen KA, Szurgot MR, Garcia BA. EpiProfile 2.0: A Computational Platform for Processing Epi-Proteomics Mass Spectrometry Data. Journal of Proteome Research. PMID 29790754 DOI: 10.1021/Acs.Jproteome.8B00133  0.8
2017 Simithy J, Sidoli S, Yuan ZF, Coradin M, Bhanu NV, Marchione DM, Klein BJ, Bazilevsky GA, McCullough CE, Magin RS, Kutateladze TG, Snyder NW, Marmorstein R, Garcia BA. Characterization of histone acylations links chromatin modifications with metabolism. Nature Communications. 8: 1141. PMID 29070843 DOI: 10.1038/S41467-017-01384-9  0.8
2017 Papillon-Cavanagh S, Lu C, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu OM, Dhaliwal S, et al. Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas. Nature Genetics. PMID 28067913 DOI: 10.1038/Ng.3757  0.8
2017 Lu C, Papillon-Cavanagh S, Gayden T, Mikael LG, Bechet D, Karamboulas C, Ailles L, Karamchandani J, Marchione DM, Garcia BA, Weinreb I, Goldstein D, Lewis PW, Dancu O, Dhaliwal S, et al. Abstract 08: Impaired H3K36 methylation defines a subset of head and neck squamous cell carcinomas Clinical Cancer Research. 23: 8-8. DOI: 10.1158/1557-3265.Aacrahns17-08  0.8
2016 Lin S, Yuan ZF, Han Y, Marchione DM, Garcia BA. Preferential phosphorylation on old histones during early mitosis in human cells. The Journal of Biological Chemistry. PMID 27226594 DOI: 10.1074/Jbc.M116.726067  0.72
2016 Zhao X, Lorent K, Wilkins B, Marchione DM, Gillespie K, Waisbourd-Zinman O, So J, Koo KA, Shin D, Porter JR, Wells RG, Blair I, Pack M. Glutathione antioxidant pathway activity and reserve determine toxicity and specificity of the biliary toxin biliatresone in zebrafish. Hepatology (Baltimore, Md.). PMID 27102575 DOI: 10.1002/Hep.28603  0.72
2016 Worth AJ, Marchione DM, Parry RC, Wang Q, Gillespie KP, Saillant NN, Sims C, Mesaros C, Snyder NW, Blair IA. LC-MS Analysis of Human Platelets as a Platform for Studying Mitochondrial Metabolism. Journal of Visualized Experiments : Jove. PMID 27077278 DOI: 10.3791/53941  0.72
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