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Guokai Chen - Publications

Affiliations: 
1998-2003 Health Sciences Univ of Macau 
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Huang M, Liao X, Wang X, Qian Y, Zhang W, Chen G, Wu Q. POZ/BTB and AT hook containing zinc finger 1 (PATZ1) suppresses differentiation and regulates metabolism in human embryonic stem cells. International Journal of Biological Sciences. 20: 1142-1159. PMID 38385086 DOI: 10.7150/ijbs.83927  0.31
2023 Zhang Y, Yi Y, Xiao X, Hu L, Xu J, Zheng D, Koc HC, Chan UI, Meng Y, Lu L, Liu W, Xu X, Shao N, Cheung ECW, Xu RH, ... Chen G, et al. Definitive Endodermal Cells Supply an in vitro Source of Mesenchymal Stem/Stromal Cells. Communications Biology. 6: 476. PMID 37127734 DOI: 10.1038/s42003-023-04810-5  0.314
2023 Godoy-Parejo C, Deng C, Xu J, Zhang Z, Ren Z, Ai N, Liu W, Ge W, Deng C, Xu X, Chin EY, Chen G. Protein Kinase C Modulation Determines the Mesoderm/Extraembryonic Fate under BMP4 induction from Human Pluripotent Stem Cells. Stem Cells (Dayton, Ohio). PMID 36648303 DOI: 10.1093/stmcls/sxad006  0.329
2020 Zhong H, Ren Z, Wang X, Miao K, Ni W, Meng Y, Lu L, Wang C, Liu W, Deng CX, Xu RH, Chen G. Stagewise keratinocyte differentiation from human embryonic stem cells by defined signal transduction modulators. International Journal of Biological Sciences. 16: 1450-1462. PMID 32210732 DOI: 10.7150/Ijbs.44414  0.429
2019 Ma B, Luo M, Yang H, Li T, Liu W, Xu F, Shu C, Chen G, Zhou Z. Generation of a human induced pluripotent stem cell line (NCCDFWi001-A) from a Marfan syndrome patient carrying two FBN1 variants (c.2613A > C and c.684_736 + 4del). Stem Cell Research. 42: 101690. PMID 31901832 DOI: 10.1016/J.Scr.2019.101690  0.347
2019 Yang Y, Ren Z, Xu F, Meng Y, Zhang Y, Ai N, Long Y, Fok HI, Deng C, Zhao X, Huang L, Zhao Q, Wang J, Liu W, Ge W, ... Chen G, et al. Endogenous IGF Signaling Directs Heterogeneous Mesoderm Differentiation in Human Embryonic Stem Cells. Cell Reports. 29: 3374-3384.e5. PMID 31825822 DOI: 10.1016/J.Celrep.2019.11.047  0.412
2019 Liu W, Deng C, Godoy-Parejo C, Zhang Y, Chen G. Developments in cell culture systems for human pluripotent stem cells. World Journal of Stem Cells. 11: 968-981. PMID 31768223 DOI: 10.4252/Wjsc.V11.I11.968  0.359
2019 Godoy-Parejo C, Deng C, Zhang Y, Liu W, Chen G. Roles of vitamins in stem cells. Cellular and Molecular Life Sciences : Cmls. PMID 31676963 DOI: 10.1007/S00018-019-03352-6  0.393
2019 Song C, Xu F, Ren Z, Zhang Y, Meng Y, Yang Y, Lingadahalli S, Cheung E, Li G, Liu W, Wan J, Zhao Y, Chen G. Elevated Exogenous Pyruvate Potentiates Mesodermal Differentiation through Metabolic Modulation and AMPK/mTOR Pathway in Human Embryonic Stem Cells. Stem Cell Reports. PMID 31353224 DOI: 10.1016/J.Stemcr.2019.06.003  0.351
2019 Godoy-Parejo C, Deng C, Liu W, Chen G. Insulin stimulates PI3K/AKT and cell adhesion to promote the survival of individualized human embryonic stem cells. Stem Cells (Dayton, Ohio). PMID 31021484 DOI: 10.1002/Stem.3026  0.353
2018 Meng Y, Ren Z, Xu F, Zhou X, Song C, Wang VY, Liu W, Lu L, Thomson JA, Chen G. Nicotinamide Promotes Cell Survival and Differentiation as Kinase Inhibitor in Human Pluripotent Stem Cells. Stem Cell Reports. PMID 30503259 DOI: 10.1016/J.Stemcr.2018.10.023  0.413
2018 Vu M, Li R, Baskfield A, Lu B, Farkhondeh A, Gorshkov K, Motabar O, Beers J, Chen G, Zou J, Espejo-Mojica AJ, Rodríguez-López A, Alméciga-Díaz CJ, Barrera LA, Jiang X, et al. Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease. Orphanet Journal of Rare Diseases. 13: 152. PMID 30220252 DOI: 10.1186/S13023-018-0886-3  0.32
2018 Yan L, Jiang B, Niu Y, Wang H, Li E, Yan Y, Sun H, Duan Y, Chang S, Chen G, Ji W, Xu RH, Si W. Intrathecal delivery of human ESC-derived mesenchymal stem cell spheres promotes recovery of a primate multiple sclerosis model. Cell Death Discovery. 5: 28. PMID 30131877 DOI: 10.1038/S41420-018-0091-0  0.352
2018 Liu W, Ren Z, Lu K, Song C, Cheung ECW, Zhou Z, Chen G. The Suppression of Medium Acidosis Improves the Maintenance and Differentiation of Human Pluripotent Stem Cells at High Density in Defined Cell Culture Medium. International Journal of Biological Sciences. 14: 485-496. PMID 29805300 DOI: 10.7150/Ijbs.24681  0.435
2018 Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson H, Reardon E, McLoughlin KC, Kaufman A, Payabyab E, Hong JA, ... ... Chen G, et al. Identification of Novel Targets for Lung Cancer Therapy Using an Induced Pluripotent Stem Cell Model. Annals of the American Thoracic Society. 15: S127-S128. PMID 29676638 DOI: 10.1513/Annalsats.201707-610Mg  0.32
2018 Luo Y, Zhu D, Xu X, Ge L, Sun X, Chen G, Chen Y. Generation of an induced pluripotent stem cell line from an adult male with 45,X/46,XY mosaicism. Stem Cell Research. 27: 42-45. PMID 29320756 DOI: 10.1016/J.Scr.2018.01.003  0.358
2017 Shukla V, Rao M, Zhang H, Beers J, Wangsa D, Wangsa D, Buishand FO, Wang Y, Yu Z, Stevenson H, Reardon E, McLoughlin KC, Kaufman A, Payabyab E, Hong JA, ... ... Chen G, et al. ASXL3 is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Research. PMID 28935813 DOI: 10.1158/0008-5472.Can-17-0570  0.383
2017 Chen G, Rao M. Derivation of Human-Induced Pluripotent Stem Cells in Chemically Defined Medium. Methods in Molecular Biology (Clifton, N.J.). 1590: 131-137. PMID 28353266 DOI: 10.1007/978-1-4939-6921-0_9  0.411
2017 Lin Y, Linask KL, Mallon B, Johnson K, Klein M, Beers J, Xie W, Du Y, Liu C, Lai Y, Zou J, Haigney M, Yang H, Rao M, Chen G. Heparin Promotes Cardiac Differentiation of Human Pluripotent Stem Cells in Chemically Defined Albumin-Free Medium, Enabling Consistent Manufacture of Cardiomyocytes. Stem Cells Translational Medicine. 6: 527-538. PMID 28191759 DOI: 10.5966/Sctm.2015-0428  0.375
2016 Long Y, Xu M, Li R, Dai S, Beers J, Chen G, Soheilian F, Baxa U, Wang M, Marugan JJ, Muro S, Li Z, Brady R, Zheng W. Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Translational Medicine. PMID 27484861 DOI: 10.5966/Sctm.2015-0373  0.366
2015 Busser BW, Lin Y, Yang Y, Zhu J, Chen G, Michelson AM. An Orthologous Epigenetic Gene Expression Signature Derived from Differentiating Embryonic Stem Cells Identifies Regulators of Cardiogenesis. Plos One. 10: e0141066. PMID 26485529 DOI: 10.1371/Journal.Pone.0141066  0.359
2015 Beers J, Linask KL, Chen JA, Siniscalchi LI, Lin Y, Zheng W, Rao M, Chen G. A cost-effective and efficient reprogramming platform for large-scale production of integration-free human induced pluripotent stem cells in chemically defined culture. Scientific Reports. 5: 11319. PMID 26066579 DOI: 10.1038/Srep11319  0.307
2014 Liu W, Chen G. Cryopreservation of human pluripotent stem cells in defined medium. Current Protocols in Stem Cell Biology. 31: 1C.17.1-1C.17.13. PMID 25366897 DOI: 10.1002/9780470151808.Sc01C17S31  0.397
2014 Efthymiou AG, Chen G, Rao M, Boehm M. Self-renewal and cell lineage differentiation strategies in human embryonic stem cells and induced pluripotent stem cells Expert Opinion On Biological Therapy. 14: 1333-1344. PMID 24881868 DOI: 10.1517/14712598.2014.922533  0.437
2014 Luo Y, Liu C, Cerbini T, San H, Lin Y, Chen G, Rao MS, Zou J. Stable enhanced green fluorescent protein expression after differentiation and transplantation of reporter human induced pluripotent stem cells generated by AAVS1 transcription activator-like effector nucleases. Stem Cells Translational Medicine. 3: 821-35. PMID 24833591 DOI: 10.5966/Sctm.2013-0212  0.399
2014 Lin Y, Li XY, Willis AL, Liu C, Chen G, Weiss SJ. Snail1-dependent control of embryonic stem cell pluripotency and lineage commitment. Nature Communications. 5: 3070. PMID 24401905 DOI: 10.1038/Ncomms4070  0.379
2014 Chen G. Cryopreservation of human pluripotent stem cells in defined conditions Stembook. PMID 23658976 DOI: 10.3824/Stembook.1.60.1  0.402
2014 Chen G. Splitting hESC/hiPSC lines with EDTA in feeder free conditions Stembook. PMID 23658972 DOI: 10.3824/Stembook.1.88.1  0.43
2012 Beers J, Gulbranson DR, George N, Siniscalchi LI, Jones J, Thomson JA, Chen G. Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nature Protocols. 7: 2029-40. PMID 23099485 DOI: 10.1038/Nprot.2012.130  0.382
2012 Chen G, Gulbranson DR, Yu P, Hou Z, Thomson JA. Thermal stability of fibroblast growth factor protein is a determinant factor in regulating self-renewal, differentiation, and reprogramming in human pluripotent stem cells. Stem Cells (Dayton, Ohio). 30: 623-30. PMID 22213113 DOI: 10.1002/Stem.1021  0.348
2011 Chen G, Gulbranson DR, Hou Z, Bolin JM, Ruotti V, Probasco MD, Smuga-Otto K, Howden SE, Diol NR, Propson NE, Wagner R, Lee GO, Antosiewicz-Bourget J, Teng JM, Thomson JA. Chemically defined conditions for human iPSC derivation and culture. Nature Methods. 8: 424-9. PMID 21478862 DOI: 10.1038/Nmeth.1593  0.348
2010 Chen G, Hou Z, Gulbranson DR, Thomson JA. Actin-myosin contractility is responsible for the reduced viability of dissociated human embryonic stem cells. Cell Stem Cell. 7: 240-8. PMID 20682449 DOI: 10.1016/J.Stem.2010.06.017  0.355
2007 Katoh M, Chen G, Roberge E, Shaulsky G, Kuspa A. Developmental commitment in Dictyostelium discoideum. Eukaryotic Cell. 6: 2038-45. PMID 17905919 DOI: 10.1128/Ec.00223-07  0.644
2007 Chen G, Zhuchenko O, Kuspa A. Immune-like phagocyte activity in the social amoeba. Science (New York, N.Y.). 317: 678-81. PMID 17673666 DOI: 10.1126/Science.1143991  0.59
2005 Chen G, Kuspa A. Prespore cell fate bias in G1 phase of the cell cycle in Dictyostelium discoideum. Eukaryotic Cell. 4: 1755-64. PMID 16215182 DOI: 10.1128/Ec.4.10.1755-1764.2005  0.634
2005 Eichinger L, Pachebat JA, Glöckner G, Rajandream MA, Sucgang R, Berriman M, Song J, Olsen R, Szafranski K, Xu Q, Tunggal B, Kummerfeld S, Madera M, Konfortov BA, Rivero F, ... ... Chen G, et al. The genome of the social amoeba Dictyostelium discoideum. Nature. 435: 43-57. PMID 15875012 DOI: 10.1038/Nature03481  0.658
2004 Chen G, Shaulsky G, Kuspa A. Tissue-specific G1-phase cell-cycle arrest prior to terminal differentiation in Dictyostelium. Development (Cambridge, England). 131: 2619-30. PMID 15128662 DOI: 10.1242/Dev.01151  0.668
2003 Sucgang R, Chen G, Liu W, Lindsay R, Lu J, Muzny D, Shaulsky G, Loomis W, Gibbs R, Kuspa A. Sequence and structure of the extrachromosomal palindrome encoding the ribosomal RNA genes in Dictyostelium Nucleic Acids Research. 31: 2361-2368. PMID 12711681 DOI: 10.1093/Nar/Gkg348  0.636
2002 Taminato A, Bagattini R, Gorjão R, Chen G, Kuspa A, Souza GM. Role for YakA, cAMP, and protein kinase A in regulation of stress responses of Dictyostelium discoideum cells. Molecular Biology of the Cell. 13: 2266-75. PMID 12134067 DOI: 10.1091/Mbc.01-11-0555  0.675
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