David A Brenner - Publications

Affiliations: 
1985- Medicine University of California, San Diego, La Jolla, CA 
Website:
https://medschool.ucsd.edu/about/leadership/Pages/brenner.aspx

500 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Nishio T, Koyama Y, Liu X, Rosenthal SB, Yamamoto G, Fuji H, Baglieri J, Li N, Brenner LN, Iwaisako K, Taura K, Hagood JS, LaRusso NF, Bera TK, Pastan I, ... Brenner DA, et al. Immunotherapy-based targeting of MSLN activated portal fibroblasts is a strategy for treatment of cholestatic liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34253615 DOI: 10.1073/pnas.2101270118  1
2021 Ramirez-Perez FI, Woodford ML, Morales-Quinones M, Grunewald ZI, Cabral-Amador FJ, Yoshida T, Brenner DA, Manrique-Acevedo C, Martinez-Lemus LA, Chandrasekar B, Padilla J. Mutation of the 5' untranslated region stem-loop mRNA structure reduces type I collagen deposition and arterial stiffness in male obese mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 34242094 DOI: 10.1152/ajpheart.00076.2021  0.01
2021 Baglieri J, Zhang C, Liang S, Liu X, Nishio T, Rosenthal SB, Dhar D, Su H, Cong M, Jia J, Hosseini M, Karin M, Kisseleva T, Brenner DA. Non-degradable collagen increases liver fibrosis but not hepatocellular carcinoma in mice. The American Journal of Pathology. PMID 34119473 DOI: 10.1016/j.ajpath.2021.05.019  1
2021 Ganguly S, Muench GA, Shang L, Rosenthal SB, Rahman G, Wang R, Wang Y, Kwon HC, Diomino AM, Kisseleva T, Soorosh P, Hosseini M, Knight R, Schnabl B, Brenner DA, et al. Non-alcoholic Steatohepatitis and HCC in a Hyperphagic Mouse Accelerated by Western Diet. Cellular and Molecular Gastroenterology and Hepatology. PMID 34062281 DOI: 10.1016/j.jcmgh.2021.05.010  1
2021 Zhou R, Llorente C, Cao J, Zaramela LS, Zeng S, Gao B, Li SZ, Welch RD, Huang FQ, Qi LW, Pan C, Huang Y, Zhou P, Beussen I, Zhang Y, ... ... Brenner DA, et al. Intestinal α1-2-fucosylation contributes to obesity and steatohepatitis in mice. Cellular and Molecular Gastroenterology and Hepatology. PMID 33631374 DOI: 10.1016/j.jcmgh.2021.02.009  1
2021 Rosenthal SB, Liu X, Ganguly S, Dhar D, Pasillas MP, Ricciardelli E, Li RZ, Troutman TD, Kisseleva T, Glass CK, Brenner DA. Heterogeneity of hepatic stellate cells in a mouse model of non-alcoholic steatohepatitis (NASH). Hepatology (Baltimore, Md.). PMID 33550587 DOI: 10.1002/hep.31743  1
2021 Gratte FD, Pasic S, Abu Bakar NDB, Gogoi-Tiwari J, Liu X, Carlessi R, Kisseleva T, Brenner DA, Ramm GA, Olynyk JK, Tirnitz-Parker JEE. Previous liver regeneration induces fibro-protective mechanisms during thioacetamide-induced chronic liver injury. The International Journal of Biochemistry & Cell Biology. 105933. PMID 33540107 DOI: 10.1016/j.biocel.2021.105933  1
2020 Jiang C, Iwaisako K, Cong M, Diggle K, Hassanein T, Brenner DA, Kisseleva T. Traditional Chinese Medicine Fuzheng Huayu Prevents Development of Liver Fibrosis in Mice. Archives of Clinical and Biomedical Research. 4: 561-580. PMID 33210080 DOI: 10.26502/acbr.50170125  1
2020 Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Yu RT, Atkins AR, Huan T, Brenner DA, Sirlin CB, et al. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. Cell Metabolism. 32: 901. PMID 33147487 DOI: 10.1016/j.cmet.2020.10.015  1
2020 Jeste DV, Di Somma S, Lee EE, Nguyen TT, Scalcione M, Biaggi A, Daly R, Liu J, Tu X, Ziedonis D, Glorioso D, Antonini P, Brenner D. Study of loneliness and wisdom in 482 middle-aged and oldest-old adults: a comparison between people in Cilento, Italy and San Diego, USA. Aging & Mental Health. 1-11. PMID 33000647 DOI: 10.1080/13607863.2020.1821170  1
2020 Jiang L, Lang S, Duan Y, Zhang X, Gao B, Chopyk J, Schwanemann LK, Ventura-Cots M, Bataller R, Bosques-Padilla F, Verna EC, Abraldes JG, Brown RS, Vargas V, Altamirano J, ... ... Brenner DA, et al. Intestinal virome in patients with alcoholic hepatitis. Hepatology (Baltimore, Md.). PMID 32654263 DOI: 10.1002/Hep.31459  1
2020 Kim YC, Ganguly S, Nespoux J, Freeman B, Zhang H, Brenner D, Dhar D, Vallon V. Western Diet Promotes Renal Injury, Inflammation, and Fibrosis in a Murine Model of Alström Syndrome. Nephron. 1-13. PMID 32629454 DOI: 10.1159/000508636  1
2020 Oh TG, Kim SM, Caussy C, Fu T, Guo J, Bassirian S, Singh S, Madamba EV, Bettencourt R, Richards L, Raffatellu M, Dorrestein PC, Yu RT, Atkins AR, Huan T, ... Brenner DA, et al. A Universal Gut-Microbiome-Derived Signature Predicts Cirrhosis. Cell Metabolism. PMID 32610095 DOI: 10.1016/J.Cmet.2020.06.005  1
2020 Riopel M, Moon JS, Bandyopadhyay GK, You S, Lam K, Liu X, Kisseleva T, Brenner D, Lee YS. Inhibition of Prolyl Hydroxylases Increases Hepatic Insulin And Decreases Glucagon Sensitivity by An HIF-2α-Dependent Mechanism. Molecular Metabolism. 101039. PMID 32534258 DOI: 10.1016/J.Molmet.2020.101039  1
2020 Baeza-Raja B, Goodyear A, Liu X, Lam K, Yamamoto L, Li Y, Dodson GS, Takeuchi T, Kisseleva T, Brenner DA, Dabbagh K. Pharmacological inhibition of P2RX7 ameliorates liver injury by reducing inflammation and fibrosis. Plos One. 15: e0234038. PMID 32492075 DOI: 10.1371/Journal.Pone.0234038  1
2020 Gao B, Emami A, Zhou R, Lang S, Duan Y, Wang Y, Jiang L, Loomba R, Brenner DA, Stärkel P, Schnabl B. Functional Microbial Responses to Alcohol Abstinence in Patients With Alcohol Use Disorder. Frontiers in Physiology. 11: 370. PMID 32390870 DOI: 10.3389/Fphys.2020.00370  1
2020 Pizza V, Antonini P, Marino R, D'Arena G, Lucibello SG, Rizzo M, Brenner DA, Jeste DV, Somma SD. Cognitive Health of Nonagenarians in Southern Italy: A Descriptive Analysis from a Cross-Sectional, Home-Based Pilot Study of Exceptional Longevity (Cilento Initiative on Aging Outcomes Or CIAO). Medicina (Kaunas, Lithuania). 56. PMID 32380778 DOI: 10.3390/Medicina56050218  0.01
2020 Pujol-Canadell M, Perrier JR, Cunha L, Shuryak I, Harken A, Garty G, Brenner DJ. Cytogenetically-based biodosimetry after high doses of radiation. Plos One. 15: e0228350. PMID 32320391 DOI: 10.1371/Journal.Pone.0228350  0.01
2020 Liu X, Rosenthal SB, Meshgin N, Baglieri J, Musallam SG, Diggle K, Lam K, Wu R, Pan SQ, Chen Y, Dorko K, Presnell S, Benner C, Hosseini M, Tsukamoto H, ... Brenner D, et al. Primary Alcohol-Activated Human and Mouse Hepatic Stellate Cells Share Similarities in Gene-Expression Profiles. Hepatology Communications. 4: 606-626. PMID 32258954 DOI: 10.1002/hep4.1483  1
2020 Zhang M, Haughey M, Wang NY, Blease K, Kapoun AM, Couto S, Belka I, Hoey T, Groza M, Hartke J, Bennett B, Cain J, Gurney A, Benish B, Castiglioni P, ... ... Brenner DA, et al. Targeting the Wnt signaling pathway through R-spondin 3 identifies an anti-fibrosis treatment strategy for multiple organs. Plos One. 15: e0229445. PMID 32160239 DOI: 10.1371/Journal.Pone.0229445  0.01
2020 Brenner DJ. Low Radiation Doses: Small Risks? No Risks? Or Risks to Only a Few? Radiology. 200212. PMID 32159453 DOI: 10.1148/Radiol.2020200212  0.01
2020 Shuryak I, Turner HC, Perrier JR, Cunha L, Canadell MP, Durrani MH, Harken A, Bertucci A, Taveras M, Garty G, Brenner DJ. A High Throughput Approach to Reconstruct Partial-Body and Neutron Radiation Exposures on an Individual Basis. Scientific Reports. 10: 2899. PMID 32076014 DOI: 10.1038/S41598-020-59695-9  0.01
2020 Xu J, Ma HY, Liu X, Rosenthal S, Baglieri J, McCubbin R, Sun M, Koyama Y, Geoffroy CG, Saijo K, Shang L, Nishio T, Maricic I, Kreifeldt M, Kusumanchi P, ... ... Brenner DA, et al. Blockade of IL-17 signaling reverses alcohol-induced liver injury and excessive alcohol drinking in mice. Jci Insight. 5. PMID 32051339 DOI: 10.1172/Jci.Insight.131277  1
2020 Suman S, Shuryak I, Kallakury B, Brenner DJ, Fornace AJ, Johnson MD, Datta K. Protons show greater relative biological effectiveness for mammary tumorigenesis with higher ERα and HER2 positive tumors relative to γ-rays in APC mice. International Journal of Radiation Oncology, Biology, Physics. PMID 32036005 DOI: 10.1016/J.Ijrobp.2020.01.031  0.01
2020 Liu X, Xu J, Rosenthal S, Zhang LJ, McCubbin R, Meshgin N, Shang L, Koyama Y, Ma HY, Sharma S, Heinz S, Glass CK, Benner C, Brenner DA, Kisseleva T. Identification of Lineage-specific Transcription Factors That Prevent Activation of Hepatic Stellate Cells and Promote Fibrosis Resolution. Gastroenterology. PMID 31982409 DOI: 10.1053/J.Gastro.2020.01.027  1
2020 Dhar D, Baglieri J, Kisseleva T, Brenner DA. Mechanisms of liver fibrosis and its role in liver cancer. Experimental Biology and Medicine (Maywood, N.J.). 1535370219898141. PMID 31924111 DOI: 10.1177/1535370219898141  1
2020 Wang Q, Pujol-Canadell M, Taveras M, Garty G, Perrier J, Bueno-Beti C, Shuryak I, Brenner DJ, Turner HC. DNA damage response in peripheral mouse blood leukocytes in vivo after variable, low-dose rate exposure. Radiation and Environmental Biophysics. PMID 31897603 DOI: 10.1007/S00411-019-00825-X  0.01
2020 Baglieri J, Liu X, Nishio T, Rosenthal SB, Kisseleva T, Brenner DA. Su1690 DEGRADATION OF COLLAGEN TYPE I IS NEEDED FOR HEPATOCELLULAR CARCINOMA DEVELOPMENT IN MICE Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)34125-1  1
2020 Loomba R, Oh TG, Kim S, Singh S, Bettencourt R, Yu RT, Brenner DA, Sirlin CB, Downes M, Evans RM. Su1594 GUT MICROBIOME METAGENOMICS REVEALS FUNGAL MYCOBIOME ALTERATION IN NAFLD CIRRHOSIS WITH VALIDATION IN A GEOGRAPHICALLY INDEPENDENT COHORT Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)34047-6  1
2020 Lam KP, Rosenthal SB, Meshgin N, Arreola R, Baglieri J, Nishio T, Diggle K, Brenner DA, Kisseleva T, Liu X. 452 Comparative Analysis Of Gene Expression Profile In Primary Human Normal, Nafld, And Nash Hepatic Stellate Cells Identifies Novel Targets For Anti-Fibrotic Therapy. Gastroenterology. 158. DOI: 10.1016/S0016-5085(20)33853-1  1
2019 Ma HY, Yamamoto G, Xu J, Liu X, Karin D, Kim JY, Alexandrov LB, Koyama Y, Nishio T, Benner C, Heinz S, Rosenthal SB, Liang S, Sun M, Karin G, ... ... Brenner DA, et al. IL-17 signaling in steatotic hepatocytes and macrophages promotes hepatocellular carcinoma in alcohol-related liver disease. Journal of Hepatology. PMID 31899206 DOI: 10.1016/J.Jhep.2019.12.016  1
2019 Yilmaz R, Müller K, Brenner D, Volk AE, Borck G, Hermann A, Meitinger T, Strom TM, Danzer KM, Ludolph AC, Andersen PM, Weishaupt JH. SQSTM1/p62 variants in 486 patients with familial ALS from Germany and Sweden. Neurobiology of Aging. PMID 31859009 DOI: 10.1016/j.neurobiolaging.2019.10.018  0.01
2019 Repin M, Pampou S, Brenner DJ, Garty G. The use of a centrifuge-free RABiT-II system for high-throughput micronucleus analysis. Journal of Radiation Research. PMID 31825079 DOI: 10.1093/jrr/rrz074  0.01
2019 Ghandhi SA, Shuryak I, Morton SR, Amundson SA, Brenner DJ. New Approaches for Quantitative Reconstruction of Radiation Dose in Human Blood Cells. Scientific Reports. 9: 18441. PMID 31804590 DOI: 10.1038/S41598-019-54967-5  0.01
2019 Daniels LB, Antonini P, Marino R, Rizzo M, Navarin S, Lucibello SG, Maisel AS, Pizza V, Brenner DA, Jeste DV, Di Somma S. Cardiovascular health of nonagenarians in southern Italy: a cross-sectional, home-based pilot study of longevity. Journal of Cardiovascular Medicine (Hagerstown, Md.). PMID 31789688 DOI: 10.2459/Jcm.0000000000000910  0.01
2019 Sun X, Seidman JS, Zhao P, Troutman TD, Spann NJ, Que X, Zhou F, Liao Z, Pasillas M, Yang X, Magida JA, Kisseleva T, Brenner DA, Downes M, Evans RM, et al. Neutralization of Oxidized Phospholipids Ameliorates Non-alcoholic Steatohepatitis. Cell Metabolism. PMID 31761566 DOI: 10.1016/J.Cmet.2019.10.014  1
2019 Kisseleva T, Brenner DA. The Crosstalk between Hepatocytes, Hepatic Macrophages, and Hepatic Stellate Cells Facilitates Alcoholic Liver Disease. Cell Metabolism. 30: 850-852. PMID 31693880 DOI: 10.1016/J.Cmet.2019.10.010  1
2019 Mukhopadhyay S, Mehrad M, Dammert P, Arrossi AV, Sarda R, Brenner DS, Maldonado F, Choi H, Ghobrial M. Lung Biopsy Findings in Severe Pulmonary Illness Associated With E-Cigarette Use (Vaping). American Journal of Clinical Pathology. PMID 31621873 DOI: 10.1093/ajcp/aqz182  0.01
2019 Gu J, Norquist A, Brooks C, Repin M, Mukherjee S, Lacombe J, Yang J, Brenner DJ, Amundson S, Zenhausern F. Development of an integrated fingerstick blood self-collection device for radiation countermeasures. Plos One. 14: e0222951. PMID 31618210 DOI: 10.1371/Journal.Pone.0222951  0.01
2019 Brenner D, Rosenbohm A, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, et al. Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations. Brain : a Journal of Neurology. PMID 31612906 DOI: 10.1093/brain/awz306  0.01
2019 Barbieri S, Babini G, Morini J, Friedland W, Buonanno M, Grilj V, Brenner DJ, Ottolenghi A, Baiocco G. Predicting DNA damage foci and their experimental readout with 2D microscopy: a unified approach applied to photon and neutron exposures. Scientific Reports. 9: 14019. PMID 31570741 DOI: 10.1038/S41598-019-50408-5  0.01
2019 Müller HP, Brenner D, Roselli F, Wiesner D, Abaei A, Gorges M, Danzer KM, Ludolph AC, Tsao W, Wong PC, Rasche V, Weishaupt JH, Kassubek J. Longitudinal diffusion tensor magnetic resonance imaging analysis at the cohort level reveals disturbed cortical and callosal microstructure with spared corticospinal tract in the ALS mouse model. Translational Neurodegeneration. 8: 27. PMID 31485326 DOI: 10.1186/S40035-019-0163-Y  0.01
2019 Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, ... ... Brenner DA, et al. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metabolism. 30: 607. PMID 31484056 DOI: 10.1016/j.cmet.2019.08.002  1
2019 Lee Y, Wang Q, Shuryak I, Brenner DJ, Turner HC. Development of a high-throughput γ-H2AX assay based on imaging flow cytometry. Radiation Oncology (London, England). 14: 150. PMID 31438980 DOI: 10.1186/S13014-019-1344-7  0.01
2019 Shuryak I, Hall EJ, Brenner DJ. In Reply to Penagaricano. International Journal of Radiation Oncology, Biology, Physics. 105: 232-233. PMID 31422813 DOI: 10.1016/J.Ijrobp.2019.05.031  0.01
2019 Garty G, Pujol-Canadell M, Brenner DJ. An injectable dosimeter for small animal irradiations. Physics in Medicine and Biology. PMID 31416056 DOI: 10.1088/1361-6560/Ab3Bb9  0.01
2019 Brenner D, Weishaupt JH. Update on amyotrophic lateral sclerosis genetics. Current Opinion in Neurology. 32: 735-739. PMID 31335339 DOI: 10.1097/WCO.0000000000000737  0.01
2019 Royba E, Repin M, Pampou S, Karan C, Brenner DJ, Garty G. RABiT-II-DCA: A Fully-automated Dicentric Chromosome Assay in Multiwell Plates. Radiation Research. PMID 31295087 DOI: 10.1667/Rr15266.1  0.01
2019 Wang L, Mazagova M, Pan C, Yang S, Brandl K, Liu J, Reilly SM, Wang Y, Miao Z, Loomba R, Lu N, Guo Q, Liu J, Yu RT, Downes M, ... ... Brenner DA, et al. YIPF6 controls sorting of FGF21 into COPII vesicles and promotes obesity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289229 DOI: 10.1073/Pnas.1904360116  1
2019 Shuryak I, Brenner DJ. MECHANISTIC MODELING PREDICTS NO SIGNIFICANT DOSE RATE EFFECT ON HEAVY-ION CARCINOGENESIS AT DOSE RATES RELEVANT FOR SPACE EXPLORATION. Radiation Protection Dosimetry. 183: 403. PMID 31150099 DOI: 10.1093/Rpd/Ncz003  0.01
2019 Turner HC, Lee Y, Weber W, Melo D, Kowell A, Ghandhi SA, Amundson SA, Brenner DJ, Shuryak I. Effect of dose and dose rate on temporal γ-H2AX kinetics in mouse blood and spleen mononuclear cells in vivo following Cesium-137 administration. Bmc Molecular and Cell Biology. 20: 13. PMID 31138230 DOI: 10.1186/s12860-019-0195-2  0.01
2019 Taraboletti A, Goudarzi M, Kabir A, Moon BH, Laiakis EC, Lacombe J, Ake P, Shoishiro S, Brenner D, Fornace AJ, Zenhausern F. Fabric Phase Sorptive Extraction - A metabolomic pre-processing approach for ionizing radiation exposure assessment. Journal of Proteome Research. PMID 31090424 DOI: 10.1021/Acs.Jproteome.9B00142  0.01
2019 Nishio T, Hu R, Koyama Y, Liang S, Rosenthal SB, Yamamoto G, Karin D, Baglieri J, Ma HY, Xu J, Liu X, Dhar D, Iwaisako K, Taura K, Brenner DA, et al. Activated Hepatic Stellate Cells and Portal Fibroblasts contribute to cholestatic liver fibrosis in MDR2 knockout mice. Journal of Hepatology. PMID 31071368 DOI: 10.1016/J.Jhep.2019.04.012  1
2019 Roman J, Barnes TR, Kervitsky DJ, Cosgrove GP, Doherty DE, Tager AM, Richeldi L, White ES, Brenner DA, Schnapp LM, Hewitson TD, Jugdutt BI, McKinsey TA, Tosi JD, Crane S, et al. The Fibrosis Across Organs Symposium: A Roadmap for Future Research Priorities. The American Journal of the Medical Sciences. 357: 405-410. PMID 31010467 DOI: 10.1016/J.Amjms.2019.02.014  0.01
2019 Baglieri J, Brenner DA, Kisseleva T. The Role of Fibrosis and Liver-Associated Fibroblasts in the Pathogenesis of Hepatocellular Carcinoma. International Journal of Molecular Sciences. 20. PMID 30959975 DOI: 10.3390/Ijms20071723  1
2019 Caussy C, Tripathi A, Humphrey G, Bassirian S, Singh S, Faulkner C, Bettencourt R, Rizo E, Richards L, Xu ZZ, Downes MR, Evans RM, Brenner DA, Sirlin CB, Knight R, et al. A gut microbiome signature for cirrhosis due to nonalcoholic fatty liver disease. Nature Communications. 10: 1406. PMID 30926798 DOI: 10.1038/S41467-019-09455-9  1
2019 Laiakis EC, Canadell MP, Grilj V, Harken AD, Garty GY, Astarita G, Brenner DJ, Smilenov L, Fornace AJ. Serum lipidomic analysis from mixed neutron/X-ray radiation fields reveals a hyperlipidemic and pro-inflammatory phenotype. Scientific Reports. 9: 4539. PMID 30872747 DOI: 10.1038/S41598-019-41083-7  0.01
2019 Caussy C, Bhargava M, Villesen IF, Gudmann NS, Leeming DJ, Karsdal MA, Faulkner C, Bao D, Liu A, Lo MT, Bettencourt R, Bassirian S, Richards L, Brenner DA, Chen CH, et al. Collagen formation assessed by PRO-C3 is an heritable trait and is associated with liver fibrosis assessed by MRE. Hepatology (Baltimore, Md.). PMID 30859582 DOI: 10.1002/Hep.30610  1
2019 Buonanno M, Grilj V, Brenner DJ. Biological effects in normal cells exposed to FLASH dose rate protons. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 30850209 DOI: 10.1016/J.Radonc.2019.02.009  0.01
2019 Wang Q, Rodrigues MA, Repin M, Pampou S, Beaton-Green LA, Perrier J, Garty G, Brenner DJ, Turner HC, Wilkins RC. Automated Triage Radiation Biodosimetry: Integrating Imaging Flow Cytometry with High-Throughput Robotics to Perform the Cytokinesis-Block Micronucleus Assay. Radiation Research. PMID 30779694 DOI: 10.1667/Rr15243.1  0.01
2019 Shuryak I, Hall EJ, Brenner DJ. Optimized Hypofractionation can Markedly Improve Tumor Control and Decrease Late Effects for Head and Neck Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 30776451 DOI: 10.1016/J.Ijrobp.2019.02.025  0.01
2019 Brenner D, Mahon P, Iohom G, Cronin M, O'Flynn C, Shorten G. Response to 'Comment on 'Fascial layers influence the spread of injectate during ultrasound-guided infraclavicular brachial plexus block: a cadaver study' (Br J Anaesth 2019; 122: e54-5)'. British Journal of Anaesthesia. 122: e56. PMID 30770060 DOI: 10.1016/j.bja.2018.12.013  0.01
2019 Chen L, Brenner DA, Kisseleva T. Combatting Fibrosis: Exosome-Based Therapies in the Regression of Liver Fibrosis. Hepatology Communications. 3: 180-192. PMID 30766956 DOI: 10.1002/hep4.1290  1
2019 Repin M, Pampou S, Garty G, Brenner DJ. RABiT-II: A Fully-Automated Micronucleus Assay System with Shortened Time to Result. Radiation Research. PMID 30657421 DOI: 10.1667/Rr15215.1  0.01
2019 Brenner D, Sieverding K, Bruno C, Lüningschrör P, Buck E, Mungwa S, Fischer L, Brockmann SJ, Ulmer J, Bliederhäuser C, Philibert CE, Satoh T, Akira S, Boillée S, Mayer B, et al. Heterozygous loss has opposing effects in early and late stages of ALS in mice. The Journal of Experimental Medicine. PMID 30635357 DOI: 10.1084/Jem.20180729  0.01
2019 Brenner D, Iohom G, Mahon P, Shorten G. Efficacy of axillary versus infraclavicular brachial plexus block in preventing tourniquet pain: A randomised trial. European Journal of Anaesthesiology. 36: 48-54. PMID 30461447 DOI: 10.1097/EJA.0000000000000928  0.01
2019 Gratte F, Gogoi-Tiwari J, Liu X, Kisseleva T, Brenner D, Olynyk J, Tirnitz-Parker J. THU-077-Fibro-protective molecular and cellular mechanisms emerge during resolution from thioacetamide-induced fibrosis Journal of Hepatology. 70. DOI: 10.1016/S0618-8278(19)30358-5  1
2019 Nishio T, Koyama Y, Yamamoto G, Brenner DA, Kisseleva T. 493 – Universal Mechanism of Myofibroblast Activation Via Interaction Between Thy1 and Mesothelin in Organ Fibrogenesis Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39978-0  1
2019 Lui X, Rosenthal SB, Meshgin N, Wu R, Diggle K, Dorko K, Presnell S, Tsukamoto H, Brenner DA, Kisseleva T. 465 – Comparative Analysis of Gene Expression in Primary Human Normal and Alcohol-Injured Hepatic Stellate Cells Identifies Novel Targets for Anti-Fibrotic Therapy Authors Gastroenterology. 156. DOI: 10.1016/S0016-5085(19)39974-3  1
2018 Caussy C, Ajmera VH, Puri P, Hsu CL, Bassirian S, Mgdsyan M, Singh S, Faulkner C, Valasek MA, Rizo E, Richards L, Brenner DA, Sirlin CB, Sanyal AJ, Loomba R. Serum metabolites detect the presence of advanced fibrosis in derivation and validation cohorts of patients with non-alcoholic fatty liver disease. Gut. PMID 30567742 DOI: 10.1136/Gutjnl-2018-317584  1
2018 Shuryak I, Brenner DJ. MECHANISTIC MODELING PREDICTS NO SIGNIFICANT DOSE RATE EFFECT ON HEAVY-ION CARCINOGENESIS AT DOSE RATES RELEVANT FOR SPACE EXPLORATION. Radiation Protection Dosimetry. PMID 30535099 DOI: 10.1093/rpd/ncy223  0.01
2018 Barbieri S, Baiocco G, Babini G, Morini J, Friedland W, Buonanno M, Grilj V, Brenner DJ, Ottolenghi A. MODELLING γ-H2AX FOCI INDUCTION TO MIMIC LIMITATIONS IN THE SCORING TECHNIQUE. Radiation Protection Dosimetry. PMID 30520984 DOI: 10.1093/Rpd/Ncy217  0.01
2018 Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Sinha N, Bettencourt R, Gara N, Valasek MA, Schnabl B, Richards L, Brenner DA, Hofmann AF, Loomba R. Serum bile acid patterns are associated with the presence of NAFLD in twins, and dose-dependent changes with increase in fibrosis stage in patients with biopsy-proven NAFLD. Alimentary Pharmacology & Therapeutics. PMID 30506692 DOI: 10.1111/Apt.15035  1
2018 Liang S, Ma HY, Zhong Z, Dhar D, Liu X, Xu J, Koyama Y, Nishio T, Karin D, Karin G, Mccubbin R, Zhang C, Hu R, Yang G, Chen L, ... ... Brenner DA, et al. NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice. Gastroenterology. PMID 30445007 DOI: 10.1053/J.Gastro.2018.11.019  1
2018 Brenner D, Müller K, Gastl R, Gorges M, Otto M, Pinkhardt EH, Kassubek J, Weishaupt JH, Ludolph AC. Analysis of CACNA1A CAG repeat lengths in patients with familial ALS. Neurobiology of Aging. PMID 30342765 DOI: 10.1016/j.neurobiolaging.2018.09.019  0.01
2018 Tazelaar GHP, Dekker AM, van Vugt JJFA, van der Spek RA, Westeneng HJ, Kool LJBG, Kenna KP, van Rheenen W, Pulit SL, McLaughlin RL, Sproviero W, Iacoangeli A, Hübers A, Brenner D, Morrison KE, et al. Association of NIPA1 repeat expansions with amyotrophic lateral sclerosis in a large international cohort. Neurobiology of Aging. PMID 30342764 DOI: 10.1016/J.Neurobiolaging.2018.09.012  0.01
2018 Allaband C, McDonald D, Vázquez-Baeza Y, Minich JJ, Tripathi A, Brenner DA, Loomba R, Smarr L, Sandborn WJ, Schnabl B, Dorrestein P, Zarrinpar A, Knight R. Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 30240894 DOI: 10.1016/J.Cgh.2018.09.017  1
2018 Lee Y, Pujol Canadell M, Shuryak I, Perrier JR, Taveras M, Patel P, Koller A, Smilenov LB, Brenner DJ, Chen EI, Turner HC. Candidate protein markers for radiation biodosimetry in the hematopoietically humanized mouse model. Scientific Reports. 8: 13557. PMID 30202043 DOI: 10.1038/S41598-018-31740-8  0.01
2018 Welch D, Buonanno M, Shuryak I, Randers-Pehrson G, Spotnitz HM, Brenner DJ. Effect of far ultraviolet light emitted from an optical diffuser on methicillin-resistant Staphylococcus aureus in vitro. Plos One. 13: e0202275. PMID 30096188 DOI: 10.1371/Journal.Pone.0202275  0.01
2018 Brenner DA. Of Mice and Men and Nonalcoholic Steatohepatitis. Hepatology (Baltimore, Md.). 68: 2059-2061. PMID 30033687 DOI: 10.1002/Hep.30186  0.01
2018 Helferich AM, Brockmann SJ, Reinders J, Deshpande D, Holzmann K, Brenner D, Andersen PM, Petri S, Thal DR, Michaelis J, Otto M, Just S, Ludolph AC, Danzer KM, Freischmidt A, et al. Dysregulation of a novel miR-1825/TBCB/TUBA4A pathway in sporadic and familial ALS. Cellular and Molecular Life Sciences : Cmls. PMID 30030593 DOI: 10.1007/s00018-018-2873-1  0.01
2018 Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. Publisher Correction: The gut-liver axis and the intersection with the microbiome. Nature Reviews. Gastroenterology & Hepatology. PMID 29785003 DOI: 10.1038/S41575-018-0031-8  1
2018 Tripathi A, Debelius J, Brenner DA, Karin M, Loomba R, Schnabl B, Knight R. The gut-liver axis and the intersection with the microbiome. Nature Reviews. Gastroenterology & Hepatology. PMID 29748586 DOI: 10.1038/S41575-018-0011-Z  1
2018 Müller K, Brenner D, Weydt P, Meyer T, Grehl T, Petri S, Grosskreutz J, Schuster J, Volk AE, Borck G, Kubisch C, Klopstock T, Zeller D, Jablonka S, Sendtner M, et al. Comprehensive analysis of the mutation spectrum in 301 German ALS families. Journal of Neurology, Neurosurgery, and Psychiatry. PMID 29650794 DOI: 10.1136/Jnnp-2017-317611  0.01
2018 Lan T, Li C, Yang G, Sun Y, Zhuang L, Ou Y, Li H, Wang G, Kisseleva T, Brenner D, Guo J. Sphingosine kinase 1 promotes liver fibrosis by preventing miR-19b-3p-mediated inhibition of CCR2. Hepatology (Baltimore, Md.). PMID 29572892 DOI: 10.1002/Hep.29885  1
2018 Caussy C, Hsu C, Lo MT, Liu A, Bettencourt R, Ajmera VH, Bassirian S, Hooker J, Sy E, Richards L, Schork N, Schnabl B, Brenner DA, Sirlin CB, Chen CH, et al. Novel link between gut-microbiome derived metabolite and shared gene-effects with hepatic steatosis and fibrosis in NAFLD. Hepatology (Baltimore, Md.). PMID 29572891 DOI: 10.1002/Hep.29892  1
2018 Shuryak I, Hall EJ, Brenner DJ. Dose dependence of accelerated repopulation in head and neck cancer: Supporting evidence and clinical implications. Radiotherapy and Oncology : Journal of the European Society For Therapeutic Radiology and Oncology. PMID 29534828 DOI: 10.1016/J.Radonc.2018.02.015  0.01
2018 Brenner DJ, Hall EJ. Are We Now Able to Define Guidelines for Moderate Hypofractionation in Prostate Cancer Radiation Therapy? International Journal of Radiation Oncology, Biology, Physics. 100: 871-873. PMID 29485065 DOI: 10.1016/J.Ijrobp.2017.12.274  0.01
2018 Ponnaiya B, Buonanno M, Welch D, Shuryak I, Randers-Pehrson G, Brenner DJ. Far-UVC light prevents MRSA infection of superficial wounds in vivo. Plos One. 13: e0192053. PMID 29466457 DOI: 10.1371/Journal.Pone.0192053  0.01
2018 Welch D, Buonanno M, Grilj V, Shuryak I, Crickmore C, Bigelow AW, Randers-Pehrson G, Johnson GW, Brenner DJ. Far-UVC light: A new tool to control the spread of airborne-mediated microbial diseases. Scientific Reports. 8: 2752. PMID 29426899 DOI: 10.1038/S41598-018-21058-W  0.01
2018 Brenner D, Yilmaz R, Müller K, Grehl T, Petri S, Meyer T, Grosskreutz J, Weydt P, Ruf W, Neuwirth C, Weber M, Pinto S, Claeys KG, Schrank B, Jordan B, et al. Hot-spot KIF5A mutations cause familial ALS. Brain : a Journal of Neurology. PMID 29342275 DOI: 10.1093/Brain/Awx370  0.01
2018 Caussy C, Hsu C, Singh S, Bassirian S, Kolar J, Faulkner C, Bettencourt R, Valasek MA, Richards LM, Brenner DA, Loomba R. Su1507 - Serum Bile Acids Alteration is Associated with the Presence of NAFLD in Twins, and Dose-Dependent Changes with Increase in Fibrosis Stage in Patients with Biopsy-Proven NAFLD Gastroenterology. 154. DOI: 10.1016/S0016-5085(18)33848-4  1
2017 Gehi AK, Shuryak I, Balter S, Vandermolen J, Meulepas JM, King R, Mehta ND, Brenner DJ, Einstein AJ. Estimating Cancer Risk Associated With Ionizing Radiation Exposure During Atrial Fibrillation Ablation. Jacc. Clinical Electrophysiology. 3: 1200-1201. PMID 29759508 DOI: 10.1016/J.Jacep.2017.04.015  0.01
2017 England MJ, Bigelow AW, Merchant MJ, Velliou E, Welch D, Brenner DJ, Kirkby KJ. Automated microbeam observation environment for biological analysis-Custom portable environmental control applied to a vertical microbeam system. Sensors and Actuators. B, Chemical. 239: 1134-1143. PMID 29515291 DOI: 10.1016/J.Snb.2016.08.076  0.01
2017 Xu J, Ma HY, Liang S, Sun M, Karin G, Koyama Y, Hu R, Quehenberger O, Davidson NO, Dennis EA, Kisseleva T, Brenner DA. The role of human cytochrome P450 2E1 in liver inflammation and fibrosis. Hepatology Communications. 1: 1043-1057. PMID 29404441 DOI: 10.1002/hep4.1115  1
2017 Drinane MC, Yaqoob U, Yu H, Luo F, Greuter T, Arab JP, Kostallari E, Verma VK, Maiers J, De Assuncao TM, Simons M, Mukhopadhyay D, Kisseleva T, Brenner DA, Urrutia R, et al. Synectin promotes fibrogenesis by regulating PDGFR isoforms through distinct mechanisms. Jci Insight. 2. PMID 29263300 DOI: 10.1172/Jci.Insight.92821  1
2017 Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, ... ... Brenner DA, et al. Publisher Correction: Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nature Communications. 8: 2137. PMID 29233961 DOI: 10.1038/S41467-017-01779-8  1
2017 Scelzo A, Di Somma S, Antonini P, Montross LP, Schork N, Brenner D, Jeste DV. Mixed-methods quantitative-qualitative study of 29 nonagenarians and centenarians in rural Southern Italy: focus on positive psychological traits. International Psychogeriatrics. 1-8. PMID 29229012 DOI: 10.1017/S1041610217002721  0.01
2017 Meulepas JM, Hauptmann M, Lubin JH, Shuryak I, Brenner DJ. Is there Unmeasured Indication Bias in Radiation-Related Cancer Risk Estimates from Studies of Computed Tomography? Radiation Research. PMID 29206598 DOI: 10.1667/Rr14807.1  0.01
2017 Shi A, Qin J, Mou B, Correll J, Weng Y, Brenner D, Feng C, Motes D, Yang W, Dong L, Bhattarai G, Ravelombola W. Genetic diversity and population structure analysis of spinach by single-nucleotide polymorphisms identified through genotyping-by-sequencing. Plos One. 12: e0188745. PMID 29190770 DOI: 10.1371/Journal.Pone.0188745  0.01
2017 Hartmann P, Hochrath K, Horvath A, Chen P, Seebauer CT, Llorente C, Wang L, Alnouti Y, Fouts DE, Stärkel P, Loomba R, Coulter S, Liddle C, Yu RT, Ling L, ... ... Brenner DA, et al. Modulation of the intestinal bile acid-FXR-FGF15 axis improves alcoholic liver disease in mice. Hepatology (Baltimore, Md.). PMID 29159825 DOI: 10.1002/Hep.29676  1
2017 Caussy C, Chen J, Alquiraish MH, Cepin S, Nguyen P, Hernandez C, Yin M, Bettencourt R, Cachay ER, Jayakumar S, Fortney L, Hooker J, Sy E, Valasek MA, Rizo E, ... ... Brenner D, et al. Association Between Obesity and Discordance in Fibrosis Stage Determination by Magnetic Resonance vs Transient Elastography in Patients with Non-alcoholic Liver Disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 29104128 DOI: 10.1016/J.Cgh.2017.10.037  1
2017 Shang L, Hosseini M, Liu X, Kisseleva T, Brenner DA. Human hepatic stellate cell isolation and characterization. Journal of Gastroenterology. PMID 29094206 DOI: 10.1007/S00535-017-1404-4  1
2017 Brenner D, Hiergeist A, Adis C, Mayer B, Gessner A, Ludolph AC, Weishaupt JH. The fecal microbiome of ALS patients. Neurobiology of Aging. 61: 132-137. PMID 29065369 DOI: 10.1016/j.neurobiolaging.2017.09.023  0.01
2017 Llorente C, Jepsen P, Inamine T, Wang L, Bluemel S, Wang HJ, Loomba R, Bajaj JS, Schubert ML, Sikaroodi M, Gillevet PM, Xu J, Kisseleva T, Ho SB, DePew J, ... ... Brenner DA, et al. Gastric acid suppression promotes alcoholic liver disease by inducing overgrowth of intestinal Enterococcus. Nature Communications. 8: 837. PMID 29038503 DOI: 10.1038/S41467-017-00796-X  1
2017 Brenner DA. Thomas E. Starzl: Transplantation pioneer. Proceedings of the National Academy of Sciences of the United States of America. 114: 10808-10809. PMID 28893997 DOI: 10.1073/Pnas.1714008114  0.01
2017 Miller AC, Gilstad J, Brenner DJ. Military Global Health Engagement and Low-Dose Ionizing Radiation. Military Medicine. 182: 1677-1679. PMID 28885925 DOI: 10.7205/Milmed-D-17-00142  0.01
2017 Caussy C, Soni M, Cui J, Bettencourt R, Schork N, Chen CH, Ikhwan MA, Bassirian S, Cepin S, Gonzalez MP, Mendler M, Kono Y, Vodkin I, Mekeel K, Haldorson J, ... ... Brenner DA, et al. Nonalcoholic fatty liver disease with cirrhosis increases familial risk for advanced fibrosis. The Journal of Clinical Investigation. PMID 28628033 DOI: 10.1172/Jci93465  1
2017 Cong M, Zhao W, Liu T, Wang P, Fan X, Zhai Q, Bao X, Zhang D, You H, Kisseleva T, Brenner DA, Jia J, Zhuang H. Protective effect of human serum amyloid P on CCl4-induced acute liver injury in mice. International Journal of Molecular Medicine. PMID 28627620 DOI: 10.3892/Ijmm.2017.3028  1
2017 Vollmann EH, Cao L, Amatucci A, Reynolds T, Hamann S, Dalkilic-Liddle I, Cameron TO, Hossbach M, Kauffman KJ, Mir FF, Anderson DG, Novobrantseva T, Koteliansky V, Kisseleva T, Brenner D, et al. Identification of Novel Fibrosis Modifiers by In Vivo siRNA Silencing. Molecular Therapy. Nucleic Acids. 7: 314-323. PMID 28624207 DOI: 10.1016/J.Omtn.2017.04.014  1
2017 Reinders ME, Wardi G, Bettencourt R, Bouland D, Bazick J, Mendler M, Vodkin I, Kalmaz D, Savides T, Brenner D, Sell RE, Loomba R. Increased risk of in-hospital mortality and non-ICU death in patients with cirrhosis after cardiac arrest. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 28602970 DOI: 10.1016/J.Cgh.2017.05.044  1
2017 Miller AC, Rivas R, Tesoro L, Kovalenko G, Kovaric N, Pavlovic P, Brenner D. Radiation exposure from depleted uranium: The radiation bystander effect. Toxicology and Applied Pharmacology. PMID 28602947 DOI: 10.1016/J.Taap.2017.06.004  0.01
2017 Welch D, Spotnitz HM, Brenner DJ. Measurement of UV Emission from a Diffusing Optical Fiber Using Radiochromic Film. Photochemistry and Photobiology. PMID 28574149 DOI: 10.1111/Php.12798  0.01
2017 Laiakis EC, Wang YW, Young EF, Harken AD, Xu Y, Smilenov L, Garty GY, Brenner DJ, Fornace AJ. Metabolic Dysregulation after Neutron Exposures Expected from an Improvised Nuclear Device. Radiation Research. PMID 28475424 DOI: 10.1667/Rr14656.1  1
2017 Loomba R, Seguritan V, Li W, Long T, Klitgord N, Bhatt A, Dulai PS, Caussy C, Bettencourt R, Highlander SK, Jones MB, Sirlin CB, Schnabl B, Brinkac L, Schork N, ... ... Brenner DA, et al. Gut Microbiome-Based Metagenomic Signature for Non-invasive Detection of Advanced Fibrosis in Human Nonalcoholic Fatty Liver Disease. Cell Metabolism. 25: 1054-1062.e5. PMID 28467925 DOI: 10.1016/J.Cmet.2017.04.001  1
2017 Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease. Mutation Research. 800: 14-28. PMID 28458064 DOI: 10.1016/J.Mrfmmm.2017.03.007  0.01
2017 Welch D, Randers-Pehrson G, Spotnitz HM, Brenner DJ. UNLAMINATED GAFCHROMIC EBT3 FILM FOR ULTRAVIOLET RADIATION MONITORING. Radiation Protection Dosimetry. 1-6. PMID 28338819 DOI: 10.1093/Rpd/Ncx016  0.01
2017 Koyama Y, Wang P, Liang S, Iwaisako K, Liu X, Xu J, Zhang M, Sun M, Cong M, Karin D, Taura K, Benner C, Heinz S, Bera T, Brenner DA, et al. Mesothelin/mucin 16 signaling in activated portal fibroblasts regulates cholestatic liver fibrosis. The Journal of Clinical Investigation. PMID 28287406 DOI: 10.1172/Jci88845  1
2017 Repin M, Pampou S, Karan C, Brenner DJ, Garty G. RABiT-II: Implementation of a High-Throughput Micronucleus Biodosimetry Assay on Commercial Biotech Robotic Systems. Radiation Research. PMID 28231025 DOI: 10.1667/Rr011Cc.1  0.01
2017 Buonanno M, Ponnaiya B, Welch D, Stanislauskas M, Randers-Pehrson G, Smilenov L, Lowy FD, Owens DM, Brenner DJ. Germicidal Efficacy and Mammalian Skin Safety of 222-nm UV Light. Radiation Research. PMID 28225654 DOI: 10.1667/Rr0010Cc.1  0.01
2017 Shuryak I, Fornace AJ, Datta K, Suman S, Kumar S, Sachs RK, Brenner DJ. Scaling Human Cancer Risks from Low LET to High LET when Dose-Effect Relationships are Complex. Radiation Research. PMID 28218889 DOI: 10.1667/Rr009Cc.1  0.01
2017 Laverty C, Brenner D, McIlwaine C, Lennon JJ, Dick JT, Lucy FE, Christian KA. Temperature rise and parasitic infection interact to increase the impact of an invasive species. International Journal For Parasitology. PMID 28214510 DOI: 10.1016/J.Ijpara.2016.12.004  0.01
2017 Garty G, Xu Y, Elliston C, Marino SA, Randers-Pehrson G, Brenner DJ. Mice and the A-Bomb: Irradiation Systems for Realistic Exposure Scenarios. Radiation Research. PMID 28211757 DOI: 10.1667/Rr008Cc.1  1
2017 Koyama Y, Brenner DA. Liver inflammation and fibrosis. The Journal of Clinical Investigation. 127: 55-64. PMID 28045404 DOI: 10.1172/Jci88881  1
2017 Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez KS, Fortney LE, Hooker J, Sy E, Alquiraish MH, Valasek MA, Rizo E, Richards L, Brenner D, Sirlin CB, Loomba R. Magnetic resonance elastography vs. transient elastography in detection of fibrosis and noninvasive measurement of steatosis in patients with biopsy-proven nonalcoholic fatty liver disease Journal of Hepatology. 66. DOI: 10.1016/S0168-8278(17)30769-9  1
2017 Kwon HC, Xu J, Ma H, Shang L, Kisseleva T, Brenner DA. Western Diet Accelerates NASH in foz/foz Mouse Gastroenterology. 152. DOI: 10.1016/S0016-5085(17)33768-X  1
2016 Park CC, Nguyen P, Hernandez C, Bettencourt R, Ramirez K, Fortney L, Hooker J, Sy E, Alquiraish MH, Valasek MA, Rizo E, Richards L, Brenner D, Sirlin CB, Loomba R. Magnetic Resonance Elastography vs Transient Elastography in Detection of Fibrosis and Noninvasive Measurement of Steatosis in Patients with Biopsy-proven Nonalcoholic Fatty Liver Disease. Gastroenterology. PMID 27911262 DOI: 10.1053/J.Gastro.2016.10.026  1
2016 Chapman MA, Mukund K, Subramaniam S, Brenner D, Lieber RL. Three Distinct Cell Populations Express Extracellular Matrix Proteins and Increase in Number During Skeletal Muscle Fibrosis. American Journal of Physiology. Cell Physiology. ajpcell.00226.2016. PMID 27881411 DOI: 10.1152/Ajpcell.00226.2016  0.01
2016 Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner D, Sirlin CB, Loomba R. Weight loss decreases magnetic resonance elastography estimated liver stiffness in nonalcoholic fatty liver disease. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. PMID 27712981 DOI: 10.1016/J.Cgh.2016.09.150  1
2016 Decaris ML, Li KW, Emson CL, Gatmaitan M, Liu S, Wang Y, Nyangau E, Colangelo M, Angel TE, Beysen C, Cui J, Hernandez C, Lazaro L, Brenner DA, Turner SM, et al. Identifying NAFLD Patients with Active Fibrosis by Measuring Extracellular Matrix Remodeling Rates in Tissue and Blood. Hepatology (Baltimore, Md.). PMID 27706836 DOI: 10.1002/Hep.28860  1
2016 Karin D, Koyama Y, Brenner D, Kisseleva T. The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis. Differentiation. 92: 84-92. PMID 27591095 DOI: 10.1016/J.Diff.2016.07.001  1
2016 Kim IH, Xu J, Liu X, Koyama Y, Ma HY, Diggle K, You YH, Schilling JM, Jeste D, Sharma K, Brenner DA, Kisseleva T. Aging increases the susceptibility of hepatic inflammation, liver fibrosis and aging in response to high-fat diet in mice. Age (Dordrecht, Netherlands). PMID 27578257 DOI: 10.1007/S11357-016-9938-6  1
2016 Koyama Y, Xu J, Liu X, Brenner DA. New Developments on the Treatment of Liver Fibrosis. Digestive Diseases (Basel, Switzerland). 34: 589-596. PMID 27332862 DOI: 10.1159/000445269  1
2016 Cui J, Chen CH, Lo MT, Schork N, Bettencourt R, Gonzalez MP, Bhatt A, Hooker J, Shaffer K, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. Shared genetic effects between hepatic steatosis and fibrosis: A prospective twin study. Hepatology (Baltimore, Md.). PMID 27315352 DOI: 10.1016/S0168-8278(16)00824-2  1
2016 Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J, Minocha J, Valasek MA, Aryafar H, Brenner DA, Sirlin CB, Loomba R. Magnetic resonance elastography identifies fibrosis in adults with alpha-1 antitrypsin deficiency liver disease: a prospective study. Alimentary Pharmacology & Therapeutics. PMID 27279429 DOI: 10.1111/Apt.13691  1
2016 Ma HY, Xu J, Liu X, Zhu Y, Gao B, Karin M, Tsukamoto H, Jeste DV, Grant I, Roberts AJ, Contet C, Geoffroy C, Zheng B, Brenner D, Kisseleva T. The role of IL-17 signaling in regulation of the liver-brain axis and intestinal permeability in Alcoholic Liver Disease. Current Pathobiology Reports. 4: 27-35. PMID 27239399 DOI: 10.1007/S40139-016-0097-3  1
2016 Cui J, Philo L, Nguyen P, Hofflich H, Hernandez C, Bettencourt R, Richards L, Salotti J, Bhatt A, Hooker J, Haufe W, Hooker C, Brenner DA, Sirlin CB, Loomba R. Sitagliptin versus placebo in the treatment of nonalcoholic fatty liver disease: A randomized controlled trial. Journal of Hepatology. PMID 27151177 DOI: 10.1016/j.jhep.2016.04.021  1
2016 Loomba R, Cui J, Wolfson T, Haufe W, Hooker J, Szeverenyi N, Ang B, Bhatt A, Wang K, Aryafar H, Behling C, Valasek MA, Lin GY, Gamst A, Brenner DA, et al. Novel 3D Magnetic Resonance Elastography for the Noninvasive Diagnosis of Advanced Fibrosis in NAFLD: A Prospective Study. The American Journal of Gastroenterology. PMID 27002798 DOI: 10.1038/Ajg.2016.65  1
2016 Wang P, Koyama Y, Liu X, Xu J, Ma HY, Liang S, Kim IH, Brenner DA, Kisseleva T. Promising Therapy Candidates for Liver Fibrosis. Frontiers in Physiology. 7: 47. PMID 26909046 DOI: 10.3389/Fphys.2016.00047  1
2016 Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models. Nuclear Medicine and Biology. 43: 179-87. PMID 26872443 DOI: 10.1016/J.Nucmedbio.2015.11.009  1
2016 Liang S, Kisseleva T, Brenner DA. The Role of NADPH Oxidases (NOXs) in Liver Fibrosis and the Activation of Myofibroblasts. Frontiers in Physiology. 7: 17. PMID 26869935 DOI: 10.3389/Fphys.2016.00017  1
2016 Wang L, Fouts DE, Stärkel P, Hartmann P, Chen P, Llorente C, DePew J, Moncera K, Ho SB, Brenner DA, Hooper LV, Schnabl B. Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation. Cell Host & Microbe. 19: 227-39. PMID 26867181 DOI: 10.1016/J.Chom.2016.01.003  1
2016 Liu X, Brenner DA. Liver: DNA methylation controls liver fibrogenesis. Nature Reviews. Gastroenterology & Hepatology. PMID 26860269 DOI: 10.1038/Nrgastro.2016.16  1
2016 Kim RG, Nguyen P, Bettencourt R, Dulai PS, Haufe W, Hooker J, Minocha J, Valasek MA, Aryafar H, Brenner DA, Sirlin CB, Loomba R. Tu1706 Magnetic Resonance Elastography Identifies Fibrosis in Adults With Alpha-1 Antitrypsin Deficiency Liver Disease: A Pilot Prospective Study Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33947-6  1
2016 Patel NS, Hooker J, Gonzalez M, Bhatt A, Nguyen P, Ramirez K, Richards L, Rizo E, Hernandez C, Kisseleva T, Schnabl B, Brenner DA, Sirlin CB, Loomba R. Mo1542 Effect of Weight Loss on MRE Estimated Stiffness in Patients With Nonalcoholic Fatty Liver Disease Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33846-X  1
2016 Cui JY, Chen C, Lo M, Schork N, Bettencourt R, Bhatt A, Hooker J, Nelson KE, Long MT, Brenner DA, Sirlin CB, Loomba R. 947 Shared Genetic Effects Between Hepatic Steatosis and Fibrosis: A Prospective Twin Study Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33560-0  1
2016 Liu X, Benner C, Heinz S, Brenner DA, Kisseleva T. 226 The Mechanism of Hepatic Stellate Cell Inactivation During Reversal of Liver Fibrosis Gastroenterology. 150. DOI: 10.1016/S0016-5085(16)33456-4  1
2016 Schnabl B, Farshchi-Heydari S, Loomba R, Mattrey RF, Hoh CK, Sirlin CB, Brenner DA, Behling CA, Vera DR. Staging of fibrosis in experimental non-alcoholic steatohepatitis by quantitative molecular imaging in rat models Nuclear Medicine and Biology. 43: 179-187. DOI: 10.1016/j.nucmedbio.2015.11.009  1
2015 Floch MH, Walker WA, Sanders ME, Nieuwdorp M, Kim AS, Brenner DA, Qamar AA, Miloh TA, Guarino A, Guslandi M, Dieleman LA, Ringel Y, Quigley EM, Brandt LJ. Recommendations for Probiotic Use-2015 Update: Proceedings and Consensus Opinion. Journal of Clinical Gastroenterology. 49: S69-73. PMID 26447969 DOI: 10.1097/Mcg.0000000000000420  1
2015 Brenner DA, Paik YH, Schnabl B. Role of Gut Microbiota in Liver Disease. Journal of Clinical Gastroenterology. 49: S25-7. PMID 26447960 DOI: 10.1097/Mcg.0000000000000391  1
2015 Loomba R, Schork N, Chen CH, Bettencourt R, Bhatt A, Ang B, Nguyen P, Hernandez C, Richards L, Salotti J, Lin S, Seki E, Nelson KE, Sirlin CB, Brenner D, et al. Heritability of Hepatic Fibrosis and Steatosis Based on a Prospective Twin Study. Gastroenterology. PMID 26299412 DOI: 10.1053/J.Gastro.2015.08.011  1
2015 Lan T, Kisseleva T, Brenner DA. Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation. Plos One. 10: e0129743. PMID 26222337 DOI: 10.1371/Journal.Pone.0129743  1
2015 Koyama Y, Brenner DA. New therapies for hepatic fibrosis. Clinics and Research in Hepatology and Gastroenterology. 39: S75-9. PMID 26206573 DOI: 10.1016/J.Clinre.2015.06.011  1
2015 Verna EC, Patel J, Bettencourt R, Nguyen P, Hernandez C, Valasek MA, Kisselva T, Brenner DA, Loomba R. Novel association between serum pentraxin-2 levels and advanced fibrosis in well-characterised patients with non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics. PMID 26119353 DOI: 10.1111/Apt.13292  1
2015 Seki E, Brenner DA. Recent advancement of molecular mechanisms of liver fibrosis. Journal of Hepato-Biliary-Pancreatic Sciences. 22: 512-8. PMID 25869468 DOI: 10.1002/Jhbp.245  1
2015 Kim IH, Kisseleva T, Brenner DA. Aging and liver disease. Current Opinion in Gastroenterology. 31: 184-91. PMID 25850346 DOI: 10.1097/Mog.0000000000000176  1
2015 Xu J, Cong M, Park TJ, Scholten D, Brenner DA, Kisseleva T. Contribution of bone marrow-derived fibrocytes to liver fibrosis. Hepatobiliary Surgery and Nutrition. 4: 34-47. PMID 25713803 DOI: 10.3978/J.Issn.2304-3881.2015.01.01  1
2015 Fang S, Suh JM, Reilly SM, Yu E, Osborn O, Lackey D, Yoshihara E, Perino A, Jacinto S, Lukasheva Y, Atkins AR, Khvat A, Schnabl B, Yu RT, Brenner DA, et al. Intestinal FXR agonism promotes adipose tissue browning and reduces obesity and insulin resistance. Nature Medicine. 21: 159-65. PMID 25559344 DOI: 10.1038/Nm.3760  1
2015 Loomba R, Sirlin CB, Ang B, Bettencourt R, Jain R, Salotti J, Soaft L, Hooker J, Kono Y, Bhatt A, Hernandez L, Nguyen P, Noureddin M, Haufe W, Hooker C, ... Brenner DA, et al. Ezetimibe for the treatment of nonalcoholic steatohepatitis: assessment by novel magnetic resonance imaging and magnetic resonance elastography in a randomized trial (MOZART trial). Hepatology (Baltimore, Md.). 61: 1239-50. PMID 25482832 DOI: 10.1002/Hep.27647  1
2015 Mazagova M, Wang L, Anfora AT, Wissmueller M, Lesley SA, Miyamoto Y, Eckmann L, Dhungana S, Pathmasiri W, Sumner S, Westwater C, Brenner DA, Schnabl B. Commensal microbiota is hepatoprotective and prevents liver fibrosis in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 29: 1043-55. PMID 25466902 DOI: 10.1096/Fj.14-259515  1
2015 Xu J, Liu X, Brenner DA, Kisseleva T. Novel perspectives on the origins of the hepatic myofibroblasts Cell Health and Cytoskeleton. 7: 111-119. DOI: 10.2147/CHC.S57679  1
2015 Verna EC, Patel JR, Bettencourt R, Kisseleva T, Brenner DA, Nguyen P, Hernandez C, Loomba R. 903 Novel Association Between Serum Pentraxin-2 Levels and Advanced Fibrosis in Well-Characterized Patients With NAFLD Gastroenterology. 148. DOI: 10.1016/S0016-5085(15)33413-2  1
2015 Koyama Y, Brenner DA. New therapies for hepatic fibrosis Clinics and Research in Hepatology and Gastroenterology. 39: S75-S79. DOI: 10.1016/j.clinre.2015.06.011  1
2015 Koyama Y, Wang P, Brenner DA, Kisseleva T. Chapter 6 - Stellate Cells, Portal Myofibroblasts, and Epithelial-to-Mesenchymal Transition Stellate Cells in Health and Disease. 87-106. DOI: 10.1016/B978-0-12-800134-9.00006-3  1
2015 Seki E, Brenner DA. Recent advancement of molecular mechanisms of liver fibrosis Journal of Hepato-Biliary-Pancreatic Sciences. 22: 512-518. DOI: 10.1002/jhbp.245  1
2015 Seki E, Brenner DA. NF-κB Signaling Pathways in Liver Diseases: Third Edition. 339-347. DOI: 10.1002/9781118663387.ch24  1
2014 Xu J, Liu X, Gao B, Karin M, Tsukamoto H, Brenner D, Kisseleva T. New Approaches for Studying Alcoholic Liver Disease. Current Pathobiology Reports. 2: 171-183. PMID 26594598 DOI: 10.1007/S40139-014-0053-Z  1
2014 McArdle PF, Kittner SJ, Ay H, Brown RD, Meschia JF, Rundek T, Wassertheil-Smoller S, Woo D, Andsberg G, Biffi A, Brenner DA, Cole JW, Corriveau R, de Bakker PI, Delavaran H, et al. Agreement between TOAST and CCS ischemic stroke classification: the NINDS SiGN study. Neurology. 83: 1653-60. PMID 25261504 DOI: 10.1212/Wnl.0000000000000942  1
2014 Loomba R, Wolfson T, Ang B, Hooker J, Behling C, Peterson M, Valasek M, Lin G, Brenner D, Gamst A, Ehman R, Sirlin C. Magnetic resonance elastography predicts advanced fibrosis in patients with nonalcoholic fatty liver disease: a prospective study. Hepatology (Baltimore, Md.). 60: 1920-8. PMID 25103310 DOI: 10.1002/Hep.27362  1
2014 Iwaisako K, Jiang C, Zhang M, Cong M, Moore-Morris TJ, Park TJ, Liu X, Xu J, Wang P, Paik YH, Meng F, Asagiri M, Murray LA, Hofmann AF, Iida T, ... Brenner DA, et al. Origin of myofibroblasts in the fibrotic liver in mice. Proceedings of the National Academy of Sciences of the United States of America. 111: E3297-305. PMID 25074909 DOI: 10.1073/Pnas.1400062111  1
2014 Lopez-Sanchez I, Dunkel Y, Roh YS, Mittal Y, De Minicis S, Muranyi A, Singh S, Shanmugam K, Aroonsakool N, Murray F, Ho SB, Seki E, Brenner DA, Ghosh P. GIV/Girdin is a central hub for profibrogenic signalling networks during liver fibrosis. Nature Communications. 5: 4451. PMID 25043713 DOI: 10.1038/Ncomms5451  1
2014 Inokuchi-Shimizu S, Park EJ, Roh YS, Yang L, Zhang B, Song J, Liang S, Pimienta M, Taniguchi K, Wu X, Asahina K, Lagakos W, Mackey MR, Akira S, Ellisman MH, ... Brenner DA, et al. TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis. The Journal of Clinical Investigation. 124: 3566-78. PMID 24983318 DOI: 10.1172/Jci74068  1
2014 Brown TM, Voeks JH, Bittner V, Brenner DA, Cushman M, Goff DC, Glasser S, Muntner P, Tabereaux PB, Safford MM. Achievement of optimal medical therapy goals for U.S. adults with coronary artery disease: results from the REGARDS Study (REasons for Geographic And Racial Differences in Stroke). Journal of the American College of Cardiology. 63: 1626-33. PMID 24534599 DOI: 10.1016/J.Jacc.2013.12.042  1
2014 Liu C, Chen X, Yang L, Kisseleva T, Brenner DA, Seki E. Transcriptional repression of the transforming growth factor β (TGF-β) pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by nuclear factor κB (NF-κB) p50 enhances TGF-β signaling in hepatic stellate cells Journal of Biological Chemistry. 289: 7082-7091. PMID 24448807 DOI: 10.1074/Jbc.M113.543769  1
2014 Schnabl B, Brenner DA. Interactions between the intestinal microbiome and liver diseases Gastroenterology. 146: 1513-1524. PMID 24440671 DOI: 10.1053/J.Gastro.2014.01.020  1
2014 Paik YH, Kim J, Aoyama T, De Minicis S, Bataller R, Brenner DA. Role of NADPH oxidases in liver fibrosis. Antioxidants & Redox Signaling. 20: 2854-72. PMID 24040957 DOI: 10.1089/Ars.2013.5619  1
2014 Brenner DA. Fra, Fra Away: The complex role of activator protein 1 in liver injury Hepatology. 59: 19-20. PMID 23904356 DOI: 10.1002/hep.26637  1
2014 Lemberger UJ, Penz-Österreicher M, Brenner D, Trauner M, Österreicher CH. P167 Lack Of Fsp1/S100A4 Attenuates Liver Fibrosis In Mice Journal of Hepatology. 60. DOI: 10.1016/S0168-8278(14)60329-9  1
2014 Loomba R, Wolfsen T, Haufe W, Hooker J, Szeverneyi N, Ang B, Bhatt A, Peterson M, Valasak M, Lin G, Gamst A, Brenner D, Sirlin C. O80 Novel 3-Dimensional Magnetic Resonance Elastography Accurately Diagnoses Nash And Advanced Fibrosis In Patients With Biopsy-Proven Nafld: A Prospective Cohort Study Journal of Hepatology. 60. DOI: 10.1016/S0168-8278(14)60082-9  1
2013 Brenner DA. Reversibility of liver fibrosis. Gastroenterology & Hepatology. 9: 737-9. PMID 24764791  0.01
2013 Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS, Brenner DA, Burgdorf S, Engelholm LH, Behrendt N, Holmbeck K, Weigert R, et al. M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway. The Journal of Cell Biology. 202: 951-66. PMID 24019537 DOI: 10.1083/Jcb.201301081  1
2013 Liu X, Xu J, Brenner DA, Kisseleva T. Reversibility of Liver Fibrosis and Inactivation of Fibrogenic Myofibroblasts. Current Pathobiology Reports. 1: 209-214. PMID 24000319 DOI: 10.1007/S40139-013-0018-7  1
2013 Loomba R, Doycheva I, Bettencourt R, Cohen B, Wassel CL, Brenner D, Barrett-Connor E. Serum γ-glutamyltranspeptidase predicts all-cause, cardiovascular and liver mortality in older adults. Journal of Clinical and Experimental Hepatology. 3: 4-11. PMID 23997501 DOI: 10.1016/J.Jceh.2012.10.004  1
2013 De Minicis S, Rychlicki C, Agostinelli L, Saccomanno S, Trozzi L, Candelaresi C, Bataller R, Millán C, Brenner DA, Vivarelli M, Mocchegiani F, Marzioni M, Benedetti A, Svegliati-Baroni G. Semaphorin 7A contributes to TGF-β-mediated liver fibrogenesis. The American Journal of Pathology. 183: 820-30. PMID 23850082 DOI: 10.1016/J.Ajpath.2013.05.030  1
2013 Fordtran JS, Goyal RK, Feldman M, Soll AH, Trier JS, Ockner RK, Larusso NF, Podolsky DK, Brenner DA, Rustgi AK, Omary MB. Gastroenterology's editors-in-chief: historical and personal perspectives of their editorships. Gastroenterology. 145: 16-31. PMID 23806784 DOI: 10.1053/J.Gastro.2013.05.019  0.01
2013 Noureddin M, Lam J, Peterson MR, Middleton M, Hamilton G, Le TA, Bettencourt R, Changchien C, Brenner DA, Sirlin C, Loomba R. Utility of magnetic resonance imaging versus histology for quantifying changes in liver fat in nonalcoholic fatty liver disease trials. Hepatology (Baltimore, Md.). 58: 1930-40. PMID 23696515 DOI: 10.1002/Hep.26455  1
2013 Conigliaro A, Amicone L, Costa V, De Santis Puzzonia M, Mancone C, Sacchetti B, Cicchini C, Garibaldi F, Brenner DA, Kisseleva T, Bianco P, Tripodi M. Evidence for a common progenitor of epithelial and mesenchymal components of the liver. Cell Death and Differentiation. 20: 1116-23. PMID 23686136 DOI: 10.1038/Cdd.2013.49  1
2013 Loomba R, Liu J, Yang HI, Lee MH, Lu SN, Wang LY, Iloeje UH, You SL, Brenner D, Chen CJ. Synergistic effects of family history of hepatocellular carcinoma and hepatitis B virus infection on risk for incident hepatocellular carcinoma. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 11: 1636-45.e1-3. PMID 23669307 DOI: 10.1016/J.Cgh.2013.04.043  1
2013 Sugano K, Podolsky DK, Brenner DA, Michalopoulos G, Tsukamoto H. Kenji Fujiwara, MD, PhD. Gastroenterology. 144: 661-3. PMID 23499284 DOI: 10.1053/J.Gastro.2013.02.031  1
2013 Meurer SK, Alsamman M, Sahin H, Wasmuth HE, Kisseleva T, Brenner DA, Trautwein C, Weiskirchen R, Scholten D. Overexpression of endoglin modulates TGF-β1-signalling pathways in a novel immortalized mouse hepatic stellate cell line. Plos One. 8: e56116. PMID 23437087 DOI: 10.1371/Journal.Pone.0056116  1
2013 Patel NS, Peterson MR, Brenner DA, Heba E, Sirlin C, Loomba R. Association between novel MRI-estimated pancreatic fat and liver histology-determined steatosis and fibrosis in non-alcoholic fatty liver disease. Alimentary Pharmacology & Therapeutics. 37: 630-9. PMID 23383649 DOI: 10.1111/Apt.12237  1
2013 Loomba R, Yang HI, Su J, Brenner D, Barrett-Connor E, Iloeje U, Chen CJ. Synergism between obesity and alcohol in increasing the risk of hepatocellular carcinoma: a prospective cohort study. American Journal of Epidemiology. 177: 333-42. PMID 23355498 DOI: 10.1093/Aje/Kws252  1
2013 Kisseleva T, Brenner DA. Inactivation of myofibroblasts during regression of liver fibrosis. Cell Cycle (Georgetown, Tex.). 12: 381-2. PMID 23324345 DOI: 10.4161/Cc.23549  1
2013 De Minicis S, Kisseleva T, Francis H, Baroni GS, Benedetti A, Brenner D, Alvaro D, Alpini G, Marzioni M. Liver carcinogenesis: rodent models of hepatocarcinoma and cholangiocarcinoma. Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association For the Study of the Liver. 45: 450-9. PMID 23177172 DOI: 10.1016/J.Dld.2012.10.008  1
2013 Miura K, Yang L, van Rooijen N, Brenner DA, Ohnishi H, Seki E. Toll-like receptor 2 and palmitic acid cooperatively contribute to the development of nonalcoholic steatohepatitis through inflammasome activation in mice. Hepatology (Baltimore, Md.). 57: 577-89. PMID 22987396 DOI: 10.1002/Hep.26081  1
2013 Schnabl B, Brenner DA. Fibroblast growth factor inducible 14 as potential target in patients with alcoholic hepatitis. Gut. 62: 335-6. PMID 22717452 DOI: 10.1136/Gutjnl-2012-302644  1
2013 Al-samman M, Meurer S, Sahin H, Wasmuth H, Kisseleva T, Brenner D, Trautwein C, Weiskirchen R, Scholten D. Effekt von Endoglin auf die Differenzierung und das Signalling in einer neuen Col-GFP-exprimierenden immortalisierten murinen Sternzell-Linie Zeitschrift Fur Gastroenterologie. 51. DOI: 10.1055/S-0032-1331901  1
2013 Alsamman M, Weiskirchen R, Wasmuth H, Brenner D, Trautwein C, Scholten D. 136 ENDOGLIN DEFICIENCY IN HEPATIC STELLATE CELLS HAS A DIFFERENTIAL EFFECT ON LIVER FIBROSIS AND TGF-b SIGNALLING IN TWO EXPERIMENTAL MODELS OF MURINE LIVER FIBROSIS Journal of Hepatology. 58. DOI: 10.1016/S0168-8278(13)60138-5  1
2013 Doycheva I, Noureddin M, Patel NS, Peterson MR, Brenner DA, Sirlin C, Loomba R. Mo1005 Effect of Weight Loss on Novel MRI Quantitative Changes in Liver and Pancreatic Fat in Patients With Biopsy-Proven Nonalcoholic Fatty Liver Disease Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63752-X  1
2013 Inokuchi S, Yang L, Zhang B, Roh YS, Pimienta M, Song J, Brenner DA, Seki E. 456 TAK1-Mediated Signaling Regulates AMPK and Autophagy Pathways That Prevent Hepatic Steatosis and Hepatocarcinogenesis in Mice Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63524-6  1
2013 Park TJ, Cong M, Jiang C, Kramer M, Lupher ML, Brenner DA, Kisseleva T. 297 Deletion of Fibrocytes in Mice Attenuates Experimental Liver Fibrosis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63499-X  1
2013 Park TJ, Liu X, Zhang M, Kisseleva T, Brenner DA. 208 Deletion of PPARy in Hepatic Stellate Cells Attenuates Regression of Liver Fibrosis Gastroenterology. 144. DOI: 10.1016/S0016-5085(13)63489-7  1
2012 Brenner DA, Kisseleva T, Scholten D, Paik YH, Iwaisako K, Inokuchi S, Schnabl B, Seki E, De Minicis S, Oesterreicher C, Taura K. Origin of myofibroblasts in liver fibrosis. Fibrogenesis & Tissue Repair. 5: S17. PMID 23259769 DOI: 10.1186/1755-1536-5-S1-S17  1
2012 Brenner DA. Next-generation academic medicine. The Journal of Clinical Investigation. 122: 4280-2. PMID 23114607 DOI: 10.1172/Jci66847  0.01
2012 Ludin A, Itkin T, Gur-Cohen S, Mildner A, Shezen E, Golan K, Kollet O, Kalinkovich A, Porat Z, D'Uva G, Schajnovitz A, Voronov E, Brenner DA, Apte RN, Jung S, et al. Monocytes-macrophages that express α-smooth muscle actin preserve primitive hematopoietic cells in the bone marrow. Nature Immunology. 13: 1072-82. PMID 22983360 DOI: 10.1038/Ni.2408  1
2012 Hartmann P, Haimerl M, Mazagova M, Brenner DA, Schnabl B. Toll-like receptor 2-mediated intestinal injury and enteric tumor necrosis factor receptor I contribute to liver fibrosis in mice. Gastroenterology. 143: 1330-40.e1. PMID 22841787 DOI: 10.1053/J.Gastro.2012.07.099  1
2012 Petrides PE, Brenner D. From biochemical analysis to targeted therapies Fibrogenesis & Tissue Repair. 5: 1-2. PMID 22830438 DOI: 10.1186/1755-1536-5-S1-S1  0.01
2012 Aoyama T, Paik YH, Watanabe S, Laleu B, Gaggini F, Fioraso-Cartier L, Molango S, Heitz F, Merlot C, Szyndralewiez C, Page P, Brenner DA. Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent. Hepatology (Baltimore, Md.). 56: 2316-27. PMID 22806357 DOI: 10.1002/Hep.25938  1
2012 Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T, Welsh DK, Brenner DA, Doyle FJ, Schultz PG, Kay SA. Identification of small molecule activators of cryptochrome. Science (New York, N.Y.). 337: 1094-7. PMID 22798407 DOI: 10.1126/Science.1223710  1
2012 Seki E, Brenner DA, Karin M. A liver full of JNK: signaling in regulation of cell function and disease pathogenesis, and clinical approaches. Gastroenterology. 143: 307-20. PMID 22705006 DOI: 10.1053/J.Gastro.2012.06.004  1
2012 Meng F, Wang K, Aoyama T, Grivennikov SI, Paik Y, Scholten D, Cong M, Iwaisako K, Liu X, Zhang M, Osterreicher CH, Stickel F, Ley K, Brenner DA, Kisseleva T. Interleukin-17 signaling in inflammatory, Kupffer cells, and hepatic stellate cells exacerbates liver fibrosis in mice. Gastroenterology. 143: 765-76.e1-3. PMID 22687286 DOI: 10.1053/J.Gastro.2012.05.049  1
2012 Kisseleva T, Cong M, Paik Y, Scholten D, Jiang C, Benner C, Iwaisako K, Moore-Morris T, Scott B, Tsukamoto H, Evans SM, Dillmann W, Glass CK, Brenner DA. Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proceedings of the National Academy of Sciences of the United States of America. 109: 9448-53. PMID 22566629 DOI: 10.1073/Pnas.1201840109  1
2012 Permutt Z, Le TA, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. Correlation between liver histology and novel magnetic resonance imaging in adult patients with non-alcoholic fatty liver disease - MRI accurately quantifies hepatic steatosis in NAFLD. Alimentary Pharmacology & Therapeutics. 36: 22-9. PMID 22554256 DOI: 10.1111/J.1365-2036.2012.05121.X  1
2012 Iwaisako K, Haimerl M, Paik YH, Taura K, Kodama Y, Sirlin C, Yu E, Yu RT, Downes M, Evans RM, Brenner DA, Schnabl B. Protection from liver fibrosis by a peroxisome proliferator-activated receptor δ agonist. Proceedings of the National Academy of Sciences of the United States of America. 109: E1369-76. PMID 22538808 DOI: 10.1073/Pnas.1202464109  1
2012 Lee JK, Bettencourt R, Brenner D, Le TA, Barrett-Connor E, Loomba R. Association between serum interleukin-6 concentrations and mortality in older adults: the Rancho Bernardo study. Plos One. 7: e34218. PMID 22514624 DOI: 10.1371/Journal.Pone.0034218  1
2012 Le TA, Chen J, Changchien C, Peterson MR, Kono Y, Patton H, Cohen BL, Brenner D, Sirlin C, Loomba R. Effect of colesevelam on liver fat quantified by magnetic resonance in nonalcoholic steatohepatitis: a randomized controlled trial. Hepatology (Baltimore, Md.). 56: 922-32. PMID 22431131 DOI: 10.1002/Hep.25731  1
2012 Fouts DE, Torralba M, Nelson KE, Brenner DA, Schnabl B. Bacterial translocation and changes in the intestinal microbiome in mouse models of liver disease. Journal of Hepatology. 56: 1283-92. PMID 22326468 DOI: 10.1016/J.Jhep.2012.01.019  1
2012 Iwaisako K, Brenner DA, Kisseleva T. What's new in liver fibrosis? The origin of myofibroblasts in liver fibrosis. Journal of Gastroenterology and Hepatology. 27: 65-8. PMID 22320919 DOI: 10.1111/J.1440-1746.2011.07002.X  1
2012 Nelson DR, Teckman J, Di Bisceglie AM, Brenner DA. Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 10: 575-80. PMID 22200689 DOI: 10.1016/J.Cgh.2011.12.028  1
2012 Kisseleva T, Brenner DA. The phenotypic fate and functional role for bone marrow-derived stem cells in liver fibrosis. Journal of Hepatology. 56: 965-72. PMID 22173163 DOI: 10.1016/J.Jhep.2011.09.021  1
2012 Dong MH, Bettencourt R, Brenner DA, Barrett-Connor E, Loomba R. Serum levels of alanine aminotransferase decrease with age in longitudinal analysis. Clinical Gastroenterology and Hepatology : the Official Clinical Practice Journal of the American Gastroenterological Association. 10: 285-90.e1. PMID 22020064 DOI: 10.1016/J.Cgh.2011.10.014  1
2012 Ajzenberg N, Lavallee PC, Labreuche J, Faille D, Huisse m, Gongora-Rivera F, Jaramillo A, Brenner D, Deplanque D, Klein IF, Touboul P, Vicaud E, Amarenco P. A Role of Platelet Activation in Lacunar Stroke Blood. 120: 1141-1141. DOI: 10.1182/Blood.V120.21.1141.1141  0.01
2012 Permutt Z, Le TAT, Peterson MR, Seki E, Brenner DA, Sirlin C, Loomba R. Tu1028 Correlation Between Liver Histology and Novel Magnetic Resonance Imaging in Adult Patients With Nonalcoholic Fatty Liver Disease Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63927-4  1
2012 Le TAT, Chen J, Changchien C, Peterson MR, Cohen BL, Kono Y, Patton H, Brenner DA, Sirlin C, Loomba R. Tu1027 Effect of Colesevelam on Magnetic Resonance Imaging Derived Fat Maps in Nonalcoholic Steatohepatitis: A Randomized Controlled Trial Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63926-2  1
2012 Yang L, Inokuchi S, Park EJ, Song J, Pimienta M, Duarte P, Zhang B, Brenner DA, Seki E. 383 Ablation of TGFbeta Receptor II Inhibits Liver Injury, Inflammation, Fibrosis and Carcinogenesis in Hepatocyte Specific TAK1 Deleted Mice Gastroenterology. 142. DOI: 10.1016/S0016-5085(12)63545-8  1
2011 Paik YH, Brenner DA. NADPH oxidase mediated oxidative stress in hepatic fibrogenesis. The Korean Journal of Hepatology. 17: 251-7. PMID 22310788 DOI: 10.3350/Kjhep.2011.17.4.251  1
2011 Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase. Hepatology Research : the Official Journal of the Japan Society of Hepatology. 41: 683-6. PMID 21711427 DOI: 10.1111/J.1872-034X.2011.00814.X  1
2011 Scholten D, Reichart D, Paik YH, Lindert J, Bhattacharya J, Glass CK, Brenner DA, Kisseleva T. Migration of fibrocytes in fibrogenic liver injury. The American Journal of Pathology. 179: 189-98. PMID 21703401 DOI: 10.1016/J.Ajpath.2011.03.049  1
2011 DeLeve LD, Jaeschke H, Kalra VK, Asahina K, Brenner DA, Tsukamoto H. 15th International Symposium on Cells of the Hepatic Sinusoid, 2010. Liver International : Official Journal of the International Association For the Study of the Liver. 31: 762-72. PMID 21645207 DOI: 10.1111/J.1478-3231.2011.02527.X  1
2011 Kisseleva T, von Köckritz-Blickwede M, Reichart D, McGillvray SM, Wingender G, Kronenberg M, Glass CK, Nizet V, Brenner DA. Fibrocyte-like cells recruited to the spleen support innate and adaptive immune responses to acute injury or infection. Journal of Molecular Medicine (Berlin, Germany). 89: 997-1013. PMID 21499735 DOI: 10.1007/S00109-011-0756-0  1
2011 Kisseleva T, Brenner DA. Anti-fibrogenic strategies and the regression of fibrosis. Best Practice & Research. Clinical Gastroenterology. 25: 305-17. PMID 21497747 DOI: 10.1016/J.Bpg.2011.02.011  1
2011 Inokuchi S, Tsukamoto H, Park E, Liu ZX, Brenner DA, Seki E. Toll-like receptor 4 mediates alcohol-induced steatohepatitis through bone marrow-derived and endogenous liver cells in mice. Alcoholism, Clinical and Experimental Research. 35: 1509-18. PMID 21463341 DOI: 10.1111/J.1530-0277.2011.01487.X  1
2011 Meng F, Wang J, Ge J, Fan X, Wang B, Han L, Kisseleva T, Paik Y, Brenner DA, Wang K. Alteration of interferon-α/β receptors in chronic hepatitis B patients. Journal of Clinical Immunology. 31: 521-32. PMID 21445562 DOI: 10.1007/s10875-011-9518-6  1
2011 Kisseleva T, Brenner DA. Is it the end of the line for the EMT? Hepatology (Baltimore, Md.). 53: 1433-5. PMID 21433040 DOI: 10.1002/hep.24312  1
2011 Paik YH, Iwaisako K, Seki E, Inokuchi S, Schnabl B, Österreicher CH, Kisseleva T, Brenner DA. The nicotinamide adenine dinucleotide phosphate oxidase (NOX) homologues NOX1 and NOX2/gp91phox mediate hepatic fibrosis in mice Hepatology. 53: 1730-1741. PMID 21384410 DOI: 10.1002/Hep.24281  1
2011 Yan AW, Fouts DE, Brandl J, Stärkel P, Torralba M, Schott E, Tsukamoto H, Nelson KE, Brenner DA, Schnabl B. Enteric dysbiosis associated with a mouse model of alcoholic liver disease. Hepatology (Baltimore, Md.). 53: 96-105. PMID 21254165 DOI: 10.1002/Hep.24018  1
2011 Chau BN, Brenner DA. What goes up must come down: the emerging role of microRNA in fibrosis. Hepatology (Baltimore, Md.). 53: 4-6. PMID 21254156 DOI: 10.1002/hep.24071  0.01
2011 Gao B, Seki E, Brenner DA, Friedman S, Cohen JI, Nagy L, Szabo G, Zakhari S. Innate immunity in alcoholic liver disease. American Journal of Physiology. Gastrointestinal and Liver Physiology. 300: G516-25. PMID 21252049 DOI: 10.1152/Ajpgi.00537.2010  1
2011 Parsons CJ, Stefanovic B, Seki E, Aoyama T, Latour AM, Marzluff WF, Rippe RA, Brenner DA. Mutation of the 5′-untranslated region stem-loop structure inhibits α1(I) collagen expression in vivo Journal of Biological Chemistry. 286: 8609-8619. PMID 21193410 DOI: 10.1074/Jbc.M110.189118  1
2011 Österreicher CH, Penz-Österreicher M, Grivennikov SI, Guma M, Koltsova EK, Datz C, Sasik R, Hardiman G, Karin M, Brenner DA. Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver. Proceedings of the National Academy of Sciences of the United States of America. 108: 308-13. PMID 21173249 DOI: 10.1073/Pnas.1017547108  1
2011 Osawa Y, Seki E, Kodama Y, Suetsugu A, Miura K, Adachi M, Ito H, Shiratori Y, Banno Y, Olefsky JM, Nagaki M, Moriwaki H, Brenner DA, Seishima M. Acid sphingomyelinase regulates glucose and lipid metabolism in hepatocytes through AKT activation and AMP-activated protein kinase suppression. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 25: 1133-44. PMID 21163859 DOI: 10.1096/Fj.10-168351  1
2011 Brenner DA, Seki E, Taura K, Kisseleva T, Deminicis S, Iwaisako K, Inokuchi S, Schnabl B, Oesterreicher CH, Paik YH, Miura K, Kodama Y. Non-alcoholic steatohepatitis-induced fibrosis: Toll-like receptors, reactive oxygen species and Jun N-terminal kinase Hepatology Research. 41: 683-686. DOI: 10.1111/j.1872-034X.2011.00814.x  1
2011 Penz-Oesterreicher M, Oesterreicher C, Iwaisako K, Brenner DA. 1053 Adiponectin Deficiency Attenuates Liver Fibrosis In Mice Journal of Hepatology. 54. DOI: 10.1016/S0168-8278(11)61055-6  1
2011 Iwaisako K, Jiang C, Scholten D, Paik Y, Meng F, Brenner DA, Kisseleva T. The Origin of Myofibroblasts Contributing to Liver Fibrosis in Mice Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63802-X  1
2011 Kisseleva T, Paik Y, Scholten D, Meng F, Iwaisako K, Jiang C, Brenner DA. Hepatic Stellate Cells Revert to an Inactive Phenotype During Regression of Fibrosis Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63801-8  1
2011 Miura K, Ohnishi H, Brenner DA, Seki E. CCR2 Promotes the Progression of NASH in Mice Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)63753-0  1
2011 Boland BS, Bettencourt R, Brenner DA, Barrett-Connor EL, Loomba R. Association Between Serum Bilirubin and Mortality in Older Adults: The Rancho Bernardo Study Gastroenterology. 140. DOI: 10.1016/S0016-5085(11)61462-5  1
2010 Conigliaro A, Brenner DA, Kisseleva T. Hepatic progenitors for liver disease: current position. Stem Cells and Cloning : Advances and Applications. 3: 39-47. PMID 24198509 DOI: 10.2147/sccaa.s6035  1
2010 Miura K, Seki E, Ohnishi H, Brenner DA. Role of toll-like receptors and their downstream molecules in the development of nonalcoholic Fatty liver disease. Gastroenterology Research and Practice. 2010: 362847. PMID 21274430 DOI: 10.1155/2010/362847  1
2010 Zhang EE, Liu Y, Dentin R, Pongsawakul PY, Liu AC, Hirota T, Nusinow DA, Sun X, Landais S, Kodama Y, Brenner DA, Montminy M, Kay SA. Cryptochrome mediates circadian regulation of cAMP signaling and hepatic gluconeogenesis. Nature Medicine. 16: 1152-6. PMID 20852621 DOI: 10.1038/Nm.2214  1
2010 De Minicis S, Seki E, Paik YH, Osterreicher CH, Kodama Y, Kluwe J, Torozzi L, Miyai K, Benedetti A, Schwabe RF, Brenner DA. Role and cellular source of nicotinamide adenine dinucleotide phosphate oxidase in hepatic fibrosis Hepatology (Baltimore, Md.). 52: 1420-1430. PMID 20690191 DOI: 10.1002/Hep.23804  1
2010 Aoyama T, Inokuchi S, Brenner DA, Seki E. CX3CL1-CX3CR1 interaction prevents carbon tetrachloride-induced liver inflammation and fibrosis in mice. Hepatology (Baltimore, Md.). 52: 1390-400. PMID 20683935 DOI: 10.1002/Hep.23795  1
2010 Loomba R, Yang HI, Su J, Brenner D, Iloeje U, Chen CJ. Obesity and alcohol synergize to increase the risk of incident hepatocellular carcinoma in men. Clinical Gastroenterology and Hepatology. 8: 891-898. PMID 20621202 DOI: 10.1016/J.Cgh.2010.06.027  1
2010 Scholten D, Osterreicher CH, Scholten A, Iwaisako K, Gu G, Brenner DA, Kisseleva T. Genetic labeling does not detect epithelial-to-mesenchymal transition of cholangiocytes in liver fibrosis in mice. Gastroenterology. 139: 987-98. PMID 20546735 DOI: 10.1053/J.Gastro.2010.05.005  1
2010 Loomba R, Rao F, Zhang L, Khandrika S, Ziegler MG, Brenner DA, O'Connor DT. Genetic covariance between gamma-glutamyl transpeptidase and fatty liver risk factors: role of beta2-adrenergic receptor genetic variation in twins. Gastroenterology. 139: 836-45, 845.e1. PMID 20537997 DOI: 10.1053/J.Gastro.2010.06.009  1
2010 Kisseleva T, Gigante E, Brenner DA. Recent advances in liver stem cell therapy. Current Opinion in Gastroenterology. 26: 395-402. PMID 20495456 DOI: 10.1097/Mog.0B013E32833A6Bec  1
2010 Brenner DA, Zweifler RM, Gomez CR, Kissela BM, Levine D, Howard G, Coull B, Howard VJ. Awareness, Treatment, and Control of Vascular Risk Factors among Stroke Survivors Journal of Stroke and Cerebrovascular Diseases. 19: 311-320. PMID 20472464 DOI: 10.1016/J.Jstrokecerebrovasdis.2009.07.001  1
2010 Miura K, Kodama Y, Inokuchi S, Schnabl B, Aoyama T, Ohnishi H, Olefsky JM, Brenner DA, Seki E. Toll-like receptor 9 promotes steatohepatitis by induction of interleukin-1beta in mice. Gastroenterology. 139: 323-34.e7. PMID 20347818 DOI: 10.1053/J.Gastro.2010.03.052  1
2010 Zhong Z, Tsukada S, Rehman H, Parsons CJ, Theruvath TP, Rippe RA, Brenner DA, Lemasters JJ. Inhibition of transforming growth factor-beta/Smad signaling improves regeneration of small-for-size rat liver grafts. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 16: 181-90. PMID 20104486 DOI: 10.1002/Lt.21966  1
2010 Inokuchi S, Aoyama T, Miura K, Osterreicher CH, Kodama Y, Miyai K, Akira S, Brenner DA, Seki E. Disruption of TAK1 in hepatocytes causes hepatic injury, inflammation, fibrosis, and carcinogenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 844-9. PMID 20080763 DOI: 10.1073/Pnas.0909781107  1
2010 Taura K, Miura K, Iwaisako K, Osterreicher CH, Kodama Y, Penz-Osterreicher M, Brenner DA. Hepatocytes do not undergo epithelial-mesenchymal transition in liver fibrosis in mice. Hepatology (Baltimore, Md.). 51: 1027-36. PMID 20052656 DOI: 10.1002/Hep.23368  1
2010 Moreno M, Gonzalo T, Kok RJ, Sancho-Bru P, van Beuge M, Swart J, Prakash J, Temming K, Fondevila C, Beljaars L, Lacombe M, van der Hoeven P, Arroyo V, Poelstra K, Brenner DA, et al. Reduction of advanced liver fibrosis by short-term targeted delivery of an angiotensin receptor blocker to hepatic stellate cells in rats. Hepatology (Baltimore, Md.). 51: 942-52. PMID 20044807 DOI: 10.1002/Hep.23419  1
2010 Sancho-Bru P, Juez E, Moreno M, Khurdayan V, Morales-Ruiz M, Colmenero J, Arroyo V, Brenner DA, Ginès P, Bataller R. Hepatocarcinoma cells stimulate the growth, migration and expression of pro-angiogenic genes in human hepatic stellate cells. Liver International : Official Journal of the International Association For the Study of the Liver. 30: 31-41. PMID 19929904 DOI: 10.1111/J.1478-3231.2009.02161.X  1
2010 Scholten D, Scholten A, Östereicher C, Brenner DA, Kisseleva T. 981 EPITHELIAL-TO-MESENCHYMAL TRANSITION (EMT) IN CHOLANGIOCYTES DOES NOT CONTRIBUTE TO THE POPULATION OF α-SMA+ MYOFIBROBLASTS IN EXPERIMENTAL MODELS OF LIVER FIBROSIS Journal of Hepatology. 52. DOI: 10.1016/S0168-8278(10)60982-8  1
2010 Miura K, Inokuchi S, Ohnishi H, Brenner DA, Seki E. 74 Toll-Like Receptor (TLR) 2 in Kupffer Cells Plays a Crucial Role in the Development of Steatohepatitis in Mice Gastroenterology. 138. DOI: 10.1016/S0016-5085(10)63571-8  1
2009 Brafman DA, de Minicis S, Seki E, Shah KD, Teng D, Brenner D, Willert K, Chien S. Investigating the role of the extracellular environment in modulating hepatic stellate cell biology with arrayed combinatorial microenvironments. Integrative Biology : Quantitative Biosciences From Nano to Macro. 1: 513-24. PMID 20023766 DOI: 10.1039/B912926J  1
2009 Brenner DA. Molecular pathogenesis of liver fibrosis. Transactions of the American Clinical and Climatological Association. 120: 361-8. PMID 19768189  0.01
2009 Osterreicher CH, Taura K, De Minicis S, Seki E, Penz-Osterreicher M, Kodama Y, Kluwe J, Schuster M, Oudit GY, Penninger JM, Brenner DA. Angiotensin-converting-enzyme 2 inhibits liver fibrosis in mice. Hepatology (Baltimore, Md.). 50: 929-38. PMID 19650157 DOI: 10.1002/Hep.23104  1
2009 Colmenero J, Bataller R, Sancho-Bru P, Domínguez M, Moreno M, Forns X, Bruguera M, Arroyo V, Brenner DA, Ginès P. Effects of losartan on hepatic expression of nonphagocytic NADPH oxidase and fibrogenic genes in patients with chronic hepatitis C American Journal of Physiology - Gastrointestinal and Liver Physiology. 297. PMID 19628656 DOI: 10.1152/Ajpgi.00162.2009  1
2009 Seki E, De Minicis S, Gwak GY, Kluwe J, Inokuchi S, Bursill CA, Llovet JM, Brenner DA, Schwabe RF. CCR1 and CCR5 promote hepatic fibrosis in mice. The Journal of Clinical Investigation. 119: 1858-70. PMID 19603542 DOI: 10.1172/Jci37444  1
2009 Kodama Y, Kisseleva T, Iwaisako K, Miura K, Taura K, De Minicis S, Osterreicher CH, Schnabl B, Seki E, Brenner DA. c-Jun N-terminal kinase-1 from hematopoietic cells mediates progression from hepatic steatosis to steatohepatitis and fibrosis in mice. Gastroenterology. 137: 1467-1477.e5. PMID 19549522 DOI: 10.1053/J.Gastro.2009.06.045  1
2009 Seki E, de Minicis S, Inokuchi S, Taura K, Miyai K, van Rooijen N, Schwabe RF, Brenner DA. CCR2 promotes hepatic fibrosis in mice. Hepatology (Baltimore, Md.). 50: 185-97. PMID 19441102 DOI: 10.1002/Hep.22952  1
2009 Kodama Y, Taura K, Miura K, Schnabl B, Osawa Y, Brenner DA. Antiapoptotic Effect of c-Jun N-terminal Kinase-1 through Mcl-1 Stabilization in TNF-Induced Hepatocyte Apoptosis Gastroenterology. 136: 1423-1434. PMID 19249395 DOI: 10.1053/J.Gastro.2008.12.064  1
2009 Brandl K, Rutschmann S, Li X, Du X, Xiao N, Schnabl B, Brenner DA, Beutler B. Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response Proceedings of the National Academy of Sciences of the United States of America. 106: 3300-3305. PMID 19202076 DOI: 10.1073/Pnas.0813036106  1
2009 Paik YH, Kim JK, Lee JI, Kang SH, Kim DY, An SH, Lee SJ, Lee DK, Han KH, Chon CY, Lee SI, Lee KS, Brenner DA. Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats Gut. 58: 1517-1527. PMID 19201774 DOI: 10.1136/Gut.2008.157420  1
2009 Adler DH, Phillips JA, Cogan JD, Iverson TM, Schnetz-Boutaud N, Stein JA, Brenner DA, Milne GL, Morrow JD, Boutaud O, Oates JA. The enteropathy of prostaglandin deficiency. Journal of Gastroenterology. 44: 1-7. PMID 19148786 DOI: 10.1007/S00535-008-2253-Y  1
2009 Kodama Y, Brenner DA. c‐Jun N‐terminal kinase signaling in the pathogenesis of nonalcoholic fatty liver disease: Multiple roles in multiple steps Hepatology. 49: 6-8. PMID 19111006 DOI: 10.1002/Hep.22710  1
2009 Gäbele E, Froh M, Arteel GE, Uesugi T, Hellerbrand C, Schölmerich J, Brenner DA, Thurman RG, Rippe RA. TNFalpha is required for cholestasis-induced liver fibrosis in the mouse. Biochemical and Biophysical Research Communications. 378: 348-53. PMID 18996089 DOI: 10.1016/J.Bbrc.2008.10.155  1
2009 Notas G, Kisseleva T, Brenner D. NK and NKT cells in liver injury and fibrosis. Clinical Immunology. 130: 16-26. PMID 18823822 DOI: 10.1016/J.Clim.2008.08.008  1
2009 Benten D, Warlich M, Follenzi A, Lütgehetmann M, Kumaran V, Brenner D, Lohse A, Gupta S. Induktion einer Fibrose in der Mausleber durch transplantierte humane Hepatische Sternzellen Zeitschrift Fur Gastroenterologie. 47: 316. DOI: 10.1055/S-0029-1241564  0.01
2009 Miura K, Seki E, Kodama Y, Inokuchi S, Brenner DA. 644 Toll-Like Receptor (TLR) 9 Mediates Steatosis and Fibrosis Through Il1β in Diet-Induced Steatohepatitis in Mice Gastroenterology. 136. DOI: 10.1016/S0016-5085(09)63705-7  1
2009 Osawa Y, Seki E, Brenner DA. Apoptosis in liver injury and liver diseases Essentials of Apoptosis: a Guide For Basic and Clinical Research. 547-564. DOI: 10.1007/978-1-60327-381-7_24  1
2009 Bataller R, Brenner DA. Pathogenesis of Hepatic Fibrosis Textbook of Gastroenterology, Fifth Edition. 1: 658-679. DOI: 10.1002/9781444303254.ch27  1
2008 De Minicis S, Seki E, Oesterreicher C, Schnabl B, Schwabe RF, Brenner DA. Reduced nicotinamide adenine dinucleotide phosphate oxidase mediates fibrotic and inflammatory effects of leptin on hepatic stellate cells. Hepatology (Baltimore, Md.). 48: 2016-26. PMID 19025999 DOI: 10.1002/Hep.22560  1
2008 Lin SL, Kisseleva T, Brenner DA, Duffield JS. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. The American Journal of Pathology. 173: 1617-27. PMID 19008372 DOI: 10.2353/Ajpath.2008.080433  1
2008 Taura K, De Minicis S, Seki E, Hatano E, Iwaisako K, Osterreicher CH, Kodama Y, Miura K, Ikai I, Uemoto S, Brenner DA. Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis Gastroenterology. 135: 1729-1738. PMID 18823985 DOI: 10.1053/J.Gastro.2008.07.065  1
2008 Miura K, Taura K, Kodama Y, Schnabl B, Brenner DA. Hepatitis C virus-induced oxidative stress suppresses hepcidin expression through increased histone deacetylase activity. Hepatology (Baltimore, Md.). 48: 1420-9. PMID 18671304 DOI: 10.1002/Hep.22486  1
2008 Schnabl B, Scholten D, Brenner DA. What is the potential role of antifibrotic agents for the treatment of liver disease? Nature Clinical Practice. Gastroenterology & Hepatology. 5: 496-7. PMID 18628735 DOI: 10.1038/Ncpgasthep1200  1
2008 Seki E, Brenner DA. Toll-like receptors and adaptor molecules in liver disease: update. Hepatology. 48: 322-335. PMID 18506843 DOI: 10.1002/Hep.22306  1
2008 Purohit V, Bode JC, Bode C, Brenner DA, Choudhry MA, Hamilton F, Kang YJ, Keshavarzian A, Rao R, Sartor RB, Swanson C, Turner JR. Alcohol, intestinal bacterial growth, intestinal permeability to endotoxin, and medical consequences: Summary of a symposium Alcohol. 42: 349-361. PMID 18504085 DOI: 10.1016/J.Alcohol.2008.03.131  1
2008 Adler DH, Cogan JD, Phillips JA, Schnetz-Boutaud N, Milne GL, Iverson T, Stein JA, Brenner DA, Morrow JD, Boutaud O, Oates JA. Inherited human cPLA(2alpha) deficiency is associated with impaired eicosanoid biosynthesis, small intestinal ulceration, and platelet dysfunction. The Journal of Clinical Investigation. 118: 2121-31. PMID 18451993 DOI: 10.1172/Jci30473  1
2008 Minicis SD, Brenner DA. Oxidative stress in alcoholic liver disease: Role of NADPH oxidase complex Journal of Gastroenterology and Hepatology. 23. PMID 18336675 DOI: 10.1111/J.1440-1746.2007.05277.X  0.01
2008 Kisseleva T, Brenner DA. Mechanisms of fibrogenesis. Experimental Biology and Medicine. 233: 109-122. PMID 18222966 DOI: 10.3181/0707-Mr-190  1
2008 Adachi M, Brenner DA. High molecular weight adiponectin inhibits proliferation of hepatic stellate cells via activation of adenosine monophosphate–activated protein kinase† Hepatology. 47: 677-685. PMID 18220291 DOI: 10.1002/Hep.21991  0.01
2008 Iimuro Y, Brenner DA. Matrix Metalloproteinase Gene Delivery for Liver Fibrosis Pharmaceutical Research. 25: 249-258. PMID 17577645 DOI: 10.1007/S11095-007-9311-7  1
2008 Seki E, Minicis SD, Schwabe RF, Brenner DA. M1565 The Role of Ccr2 in Hepatic Fibrosis and Cancer Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63712-9  1
2008 Kisseleva T, Notas G, Taura K, Kodama Y, Minicis SD, Kramer M, Hesson DP, Pelura T, Brenner DA. 578 Human Serum Amyloid P (Hsap) Inhibits Bile Duct Ligation Induced Liver Fibrosis in Mice Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63586-6  1
2008 Miura K, Taura K, Kodama Y, Brenner DA. 577 HCV-Induced Oxidative Stress Suppresses Basal and Il6-Stimulated Hepcidin Expression in Human Hepatoma Cell Lines Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63585-4  1
2008 Kodama Y, Taura K, Miura K, Osawa Y, Brenner DA. 466 Anti-Apoptotic Effect of Jnk1 Through Mcl-1 Stabilization in TNFα-Induced Hepatocyte Apoptosis Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63580-5  1
2008 Adachi M, Seki E, Hibi T, Brenner DA. 364 High Molecular Weight Adiponectin Inhibits Proliferation of Hepatic Stellate Cells Via Activation of AMP-Activated Protein Kinase (Ampk) Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63570-2  1
2008 Minicis SD, Seki E, Oesterreicher C, Kodama Y, Kluwe J, Schwabe RF, Brenner DA. 362 Phagocytic and Non-Phagocytic NADPH-Oxidase Isoforms Differentially Regulate Fibrosis But Not Steatosis in the Liver Gastroenterology. 134. DOI: 10.1016/S0016-5085(08)63568-4  1
2008 Minicis SD, Seki E, Marzioni M, Osterreicher CH, Kodama Y, Kluwe J, Schwabe RF, Benedetti A, Brenner DA. Phagocytic and non-phagocytic NADPH-oxidase isoforms differentially regulate fibrosis but not steatosis in the liver Digestive and Liver Disease. 40. DOI: 10.1016/J.Dld.2008.07.165  1
2007 Sancho-Bru P, Bataller R, Fernandez-Varo G, Moreno M, Ramalho LN, Colmenero J, Marí M, Clària J, Jiménez W, Arroyo V, Brenner DA, Ginès P. Bradykinin Attenuates Hepatocellular Damage and Fibrosis in Rats With Chronic Liver Injury Gastroenterology. 133: 2019-2028. PMID 18054572 DOI: 10.1053/J.Gastro.2007.09.023  1
2007 Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF. TLR4 enhances TGF-beta signaling and hepatic fibrosis. Nature Medicine. 13: 1324-32. PMID 17952090 DOI: 10.1038/Nm1663  1
2007 Miura K, Yoshino R, Hirai Y, Goto T, Ohshima S, Mikami K, Yoneyama K, Watanabe D, Sato M, Senoo H, Kodama Y, Osawa Y, Brenner DA, Watanabe S. Epimorphin, a morphogenic protein, induces proteases in rodent hepatocytes through NF-kappaB. Journal of Hepatology. 47: 834-43. PMID 17935821 DOI: 10.1016/J.Jhep.2007.07.024  1
2007 Tacke F, Trautwein C, Yagmur E, Hellerbrand C, Wiest R, Brenner DA, Schnabl B. Up-regulated eotaxin plasma levels in chronic liver disease patients indicate hepatic inflammation, advanced fibrosis and adverse clinical course. Journal of Gastroenterology and Hepatology. 22: 1256-64. PMID 17688666 DOI: 10.1111/J.1440-1746.2006.04621.X  1
2007 Mencin A, Seki E, Osawa Y, Kodama Y, Minicis SD, Knowles M, Brenner DA. Alpha-1 antitrypsin Z protein (PiZ) increases hepatic fibrosis in a murine model of cholestasis. Hepatology. 46: 1443-1452. PMID 17668872 DOI: 10.1002/Hep.21832  1
2007 Schwabe RF, Brenner DA. Nuclear Factor-κB in the Liver: Friend or Foe? Gastroenterology. 132: 2601-2604. PMID 17570232 DOI: 10.1053/J.Gastro.2007.04.058  1
2007 Kisseleva T, Brenner DA. Role of hepatic stellate cells in fibrogenesis and the reversal of fibrosis Journal of Gastroenterology and Hepatology. 22. PMID 17567473 DOI: 10.1111/J.1440-1746.2006.04658.X  1
2007 Seki E, Brenner DA. The role of NF-κB in hepatocarcinogenesis: Promoter or suppressor? Journal of Hepatology. 47: 307-309. PMID 17566588 DOI: 10.1016/J.Jhep.2007.05.006  1
2007 Minicis SD, Brenner DA. NOX in liver fibrosis. Archives of Biochemistry and Biophysics. 462: 266-272. PMID 17531188 DOI: 10.1016/J.Abb.2007.04.016  0.04
2007 Kaplan LM, Klein S, Boden G, Brenner DA, Gostout CJ, Lavine JE, Popkin BM, Schirmer BD, Seeley RJ, Yanovski SZ, Cominelli F. Report of the American Gastroenterological Association (AGA) Institute Obesity Task Force. Gastroenterology. 132: 2272-5. PMID 17498517 DOI: 10.1053/J.Gastro.2007.03.061  1
2007 De Minicis S, Seki E, Uchinami H, Kluwe J, Zhang Y, Brenner DA, Schwabe RF. Gene expression profiles during hepatic stellate cell activation in culture and in vivo. Gastroenterology. 132: 1937-46. PMID 17484886 DOI: 10.1053/J.Gastro.2007.02.033  1
2007 Tacke F, Gäbele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Schölmerich J, Schnabl B. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells. Digestive Diseases and Sciences. 52: 3404-15. PMID 17415633 DOI: 10.1007/S10620-007-9758-8  1
2007 Adachi M, Osawa Y, Uchinami H, Kitamura T, Accili D, Brenner DA. The forkhead transcription factor FoxO1 regulates proliferation and transdifferentiation of hepatic stellate cells. Gastroenterology. 132: 1434-46. PMID 17408630 DOI: 10.1053/J.Gastro.2007.01.033  1
2007 Osterreicher CH, Stickel F, Brenner DA. Genomics of liver fibrosis and cirrhosis. Seminars in Liver Disease. 27: 28-43. PMID 17295175 DOI: 10.1055/S-2006-960169  1
2007 Österreicher CH, Brenner DA. The genetics of nonalcoholic fatty liver disease Annals of Hepatology. 6: 83-88. DOI: 10.1016/S1665-2681(19)31936-2  1
2007 Siegmund SY, Qian T, Minicis Sd, Harvey-White J, Kunos G, Vinod KY, Hungund B, Brenner DA, Schwabe RF. [339] The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis In Primary Hepatic Stellate Cells Via Membrane Cholesterol And Mitochondrial Ros Production Independently Of Cannabinoid-Receptors Or Nadph Oxidase Activation Journal of Hepatology. 46. DOI: 10.1016/S0168-8278(07)61937-0  1
2006 Osawa Y, Seki E, Adachi M, Taura K, Kodama Y, Siegmund SV, Schwabe RF, Brenner DA. Systemic mediators induce fibrogenic effects in normal liver after partial bile duct ligation. Liver International. 26: 1138-1147. PMID 17032415 DOI: 10.1111/J.1478-3231.2006.01346.X  1
2006 Kisseleva T, Brenner DA. Hepatic stellate cells and the reversal of fibrosis. Journal of Gastroenterology and Hepatology. 21. PMID 16958681 DOI: 10.1111/J.1440-1746.2006.04584.X  1
2006 Paik YH, Brenner DA. Immunosuppression, Hepatitis B Virus Variants: Synergistic Role in Hepatic Fibrogenesis Gastroenterology. 131: 957-960. PMID 16952565 DOI: 10.1053/j.gastro.2006.07.029  1
2006 Uchinami H, Seki E, Brenner DA, D'Armiento J. Loss of MMP 13 attenuates murine hepatic injury and fibrosis during cholestasis. Hepatology (Baltimore, Md.). 44: 420-9. PMID 16871591 DOI: 10.1002/Hep.21268  1
2006 Zhong Z, Schwabe RF, Kai Y, He L, Yang L, Bunzendahl H, Brenner DA, Lemasters JJ. Liver regeneration is suppressed in small-for-size liver grafts after transplantation: involvement of c-Jun N-terminal kinase, cyclin D1, and defective energy supply. Transplantation. 82: 241-50. PMID 16858288 DOI: 10.1097/01.Tp.0000228867.98158.D2  1
2006 Kisseleva T, Uchinami H, Feirt N, Quintana-Bustamante O, Segovia JC, Schwabe RF, Brenner DA. Bone marrow-derived fibrocytes participate in pathogenesis of liver fibrosis. Journal of Hepatology. 45: 429-438. PMID 16846660 DOI: 10.1016/J.Jhep.2006.04.014  1
2006 De Minicis S, Bataller R, Brenner DA. NADPH Oxidase in the Liver: Defensive, Offensive, or Fibrogenic? Gastroenterology. 131: 272-275. PMID 16831609 DOI: 10.1053/J.Gastro.2006.05.048  1
2006 Sancho-Bru P, Bataller R, Colmenero J, Gasull X, Moreno M, Arroyo V, Brenner DA, Ginès P. Norepinephrine induces calcium spikes and proinflammatory actions in human hepatic stellate cells. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G877-84. PMID 16782692 DOI: 10.1152/Ajpgi.00537.2005  1
2006 Schwabe RF, Seki E, Brenner DA. Toll-like receptor signaling in the liver. Gastroenterology. 130: 1886-1900. PMID 16697751 DOI: 10.1053/J.Gastro.2006.01.038  1
2006 Klein S, Mittendorfer B, Eagon JC, Patterson B, Grant L, Feirt N, Seki E, Brenner D, Korenblat K, McCrea J. Gastric Bypass Surgery Improves Metabolic and Hepatic Abnormalities Associated With Nonalcoholic Fatty Liver Disease Gastroenterology. 130: 1564-1572. PMID 16697719 DOI: 10.1053/J.Gastro.2006.01.042  1
2006 Brenner DA. The future of gastroenterology and gastroenterology. Gastroenterology. 130: 1562-1562. PMID 16697718 DOI: 10.1053/J.Gastro.2006.03.048  0.01
2006 Paik YH, Lee KS, Lee HJ, Yang KM, Lee SJ, Lee DK, Han KH, Chon CY, Lee SI, Moon YM, Brenner DA. Hepatic stellate cells primed with cytokines upregulate inflammation in response to peptidoglycan or lipoteichoic acid. Laboratory Investigation; a Journal of Technical Methods and Pathology. 86: 676-86. PMID 16619004 DOI: 10.1038/Labinvest.3700422  1
2006 Lehnert M, Uehara T, Bradford BU, Lind H, Zhong Z, Brenner DA, Marzi I, Lemasters JJ. Lipopolysaccharide-binding protein modulates hepatic damage and the inflammatory response after hemorrhagic shock and resuscitation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 291: G456-63. PMID 16614372 DOI: 10.1152/Ajpgi.00480.2005  1
2006 Lehmann TG, Luedde T, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA. Minimizing oxidative stress by gene delivery of superoxide dismutase accelerates regeneration after transplantation of reduced-size livers in the rat. Liver Transplantation : Official Publication of the American Association For the Study of Liver Diseases and the International Liver Transplantation Society. 12: 550-9. PMID 16555330 DOI: 10.1002/Lt.20632  1
2006 Schwabe RF, Brenner DA. Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways American Journal of Physiology-Gastrointestinal and Liver Physiology. 290. PMID 16537970 DOI: 10.1152/Ajpgi.00422.2005  1
2006 Gmel G, Pirola RC, Wilson JS, Whitcomb DC, Adachi M, Brenner DA, Singer MV, Taylor B, Rehm J, Rajendram R, Preedy VR, Pfützer RH, Schneider A, Bergheim I, McClain CJ, et al. Subject Index Vol. 23, 2005 Digestive Diseases. 23: 311-312. DOI: 10.1159/000091810  1
2006 Siegmund SV, Brenner DA, Schwabe RF. The Endocannabinoid Anandamide Selectively Induces Cell Death in Hepatoma Cell Lines Zeitschrift Fur Gastroenterologie. 44. DOI: 10.1055/S-2006-931702  1
2006 Benten D, Kumaran V, Joseph B, Petersen J, Brenner D, Gupta S. Die effiziente Markierung hepatischer Sternzellen ermöglicht die Analyse der intrahepatischen Integration nach der Zelltransplantation Zeitschrift Fur Gastroenterologie. 44. DOI: 10.1055/S-2006-931628  0.01
2006 Siegmund S, Qian T, Harvey-White J, Kunos G, Brenner D, Schwabe R. The Endocannabinoid 2-Arachidonoyl Glycerol Induces Apoptosis in Primary Hepatic Stellate Cells and Is Upregulated During Hepatic Fibrogenesis Zeitschrift Fur Gastroenterologie. 44. DOI: 10.1055/S-2006-931625  1
2006 Sancho-Bru P, Bataller R, Juez E, Khurdayan V, Moreno M, Colmenero J, Arroyo V, Brenner DA, Ginès P. 58 Hepatocarcinoma cells stimulate proliferation and migration and inhibit fibrogenic actions in human hepatic stellate cells: Regulation by hepatitis C virus proteins Journal of Hepatology. 44. DOI: 10.1016/S0168-8278(06)80059-0  1
2005 Siegmund SV, Dooley S, Brenner DA. Molecular mechanisms of alcohol-induced hepatic fibrosis. Digestive Diseases. 23: 264-274. PMID 16508291 DOI: 10.1159/000090174  0.01
2005 Adachi M, Brenner DA. Clinical syndromes of alcoholic liver disease. Digestive Diseases. 23: 255-263. PMID 16508290 DOI: 10.1159/000090173  0.01
2005 Siegmund SV, Brenner DA. Molecular pathogenesis of alcohol-induced hepatic fibrosis. Alcoholism: Clinical and Experimental Research. 29. PMID 16344593 DOI: 10.1097/01.Alc.0000189275.97419.58  0.01
2005 Stefanovic L, Brenner DA, Stefanovic B. Direct hepatotoxic effect of KC chemokine in the liver without infiltration of neutrophils. Experimental Biology and Medicine (Maywood, N.J.). 230: 573-86. PMID 16118408 DOI: 10.1177/153537020523000809  1
2005 Bataller R, Sancho-Bru P, Ginès P, Brenner DA. Liver fibrogenesis: A new role for the renin-angiotensin system Antioxidants and Redox Signaling. 7: 1346-1355. PMID 16115040 DOI: 10.1089/Ars.2005.7.1346  1
2005 Schnabl B, Hu K, Mühlbauer M, Hellerbrand C, Stefanovic B, Brenner DA, Schölmerich J. Zinc finger protein 267 is up-regulated during the activation process of human hepatic stellate cells and functions as a negative transcriptional regulator of MMP-10 Biochemical and Biophysical Research Communications. 335: 87-96. PMID 16054593 DOI: 10.1016/J.Bbrc.2005.07.043  1
2005 Yang L, Bataller R, Dulyx J, Coffman TM, Ginès P, Rippe RA, Brenner DA. Attenuated hepatic inflammation and fibrosis in angiotensin type 1a receptor deficient mice Journal of Hepatology. 43: 317-323. PMID 15964094 DOI: 10.1016/J.Jhep.2005.02.034  1
2005 Yang L, Magness ST, Bataller R, Rippe RA, Brenner DA. NF-κB activation in Kupffer cells after partial hepatectomy American Journal of Physiology - Gastrointestinal and Liver Physiology. 289. PMID 15905413 DOI: 10.1152/Ajpgi.00526.2004  1
2005 Uehara T, Bennett B, Sakata ST, Satoh Y, Bilter GK, Westwick JK, Brenner DA. JNK mediates hepatic ischemia reperfusion injury. Journal of Hepatology. 42: 850-9. PMID 15885356 DOI: 10.1016/J.Jhep.2005.01.030  1
2005 Siegmund SV, Uchinami H, Osawa Y, Brenner DA, Schwabe RF. Anandamide induces necrosis in primary hepatic stellate cells Hepatology. 41: 1085-1095. PMID 15841466 DOI: 10.1002/Hep.20667  1
2005 Bataller R, Gäbele E, Parsons CJ, Morris T, Yang L, Schoonhoven R, Brenner DA, Rippe RA. Systemic infusion of angiotensin II exacerbates liver fibrosis in bile duct-ligated rats. Hepatology (Baltimore, Md.). 41: 1046-55. PMID 15841463 DOI: 10.1002/Hep.20665  1
2005 Li Y, Schwabe RF, DeVries-Seimon T, Yao PM, Gerbod-Giannone MC, Tall AR, Davis RJ, Flavell R, Brenner DA, Tabas I. Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis. The Journal of Biological Chemistry. 280: 21763-72. PMID 15826936 DOI: 10.1074/Jbc.M501759200  1
2005 Luedde T, Assmus U, Wüstefeld T, Meyer Zu Vilsendorf A, Roskams T, Schmidt-Supprian M, Rajewsky K, Brenner DA, Manns MP, Pasparakis M, Trautwein C. Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury Journal of Clinical Investigation. 115: 849-859. PMID 15776110 DOI: 10.1172/Jci23493  1
2005 Modlin IM, Adler G, Alexander K, Arnold R, Brenner DA, Corazziari E, Floch MH, LaPorte RE, Peterson WL, Quigley EM, Shapiro MD, Spechler SJ, Spiller RC, Tytgat GN, Wiegers W. Information assimilation and distribution challenges and goals for real and virtual journals. Journal of Clinical Gastroenterology. 39: 181-8. PMID 15718859 DOI: 10.1097/01.Mcg.0000152791.45765.32  1
2005 Gäbele E, Reif S, Tsukada S, Bataller R, Yata Y, Morris T, Schrum LW, Brenner DA, Rippe RA. The role of p70S6K in hepatic stellate cell collagen gene expression and cell proliferation Journal of Biological Chemistry. 280: 13374-13382. PMID 15677443 DOI: 10.1074/Jbc.M409444200  1
2005 Sanz S, Pucilowska JB, Liu S, Rodríguez-Ortigosa CM, Lund PK, Brenner DA, Fuller CR, Simmons JG, Pardo A, Martínez-Chantar ML, Fagin JA, Prieto J. Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury. Gut. 54: 134-41. PMID 15591519 DOI: 10.1136/gut.2003.024505  1
2005 Bataller R, Brenner DA. Erratum: Liver fibrosis (Journal of Clinical Investigation (2005) 115 (209-218) DOI:10.1172/JCI200524282) Journal of Clinical Investigation. 115. DOI: 10.1172/Jci200524282C1  1
2005 Gäbele E, Mühlbauer M, Wiest R, Brenner D, Rippe R, Hellerbrand C, Schölmerich J, Froh M. Die Cholestase-induzierte Leberschädigung und fibrose ist bei TNFα Knockout Mäusen vermindert ausgeprägt Zeitschrift Fur Gastroenterologie. 43. DOI: 10.1055/S-2005-921816  1
2004 Brenner DA. Data from arrays: an embarrassment of riches. Gastroenterology. 127: 1659. PMID 15578500 DOI: 10.1053/J.Gastro.2004.10.038  0.01
2004 Harada N, Hatano E, Koizumi N, Nitta T, Yoshida M, Yamamoto N, Brenner DA, Yamaoka Y. Akt activation protects rat liver from ischemia/reperfusion injury Journal of Surgical Research. 121: 159-170. PMID 15501455 DOI: 10.1016/J.Jss.2004.04.016  1
2004 Rippe RA, Brenner DA. From quiescence to activation: Gene regulation in hepatic stellate cells Gastroenterology. 127: 1260-1262. PMID 15481004 DOI: 10.1053/J.Gastro.2004.08.028  1
2004 Magness ST, Bataller R, Yang L, Brenner DA. A dual reporter gene transgenic mouse demonstrates heterogeneity in hepatic fibrogenic cell populations Hepatology. 40: 1151-1159. PMID 15389867 DOI: 10.1002/Hep.20427  1
2004 Parsons CJ, Bradford BU, Pan CQ, Cheung E, Schauer M, Knorr A, Krebs B, Kraft S, Zahn S, Brocks B, Feirt N, Mei B, Cho MS, Ramamoorthi R, Roldan G, ... ... Brenner DA, et al. Antifibrotic effects of a tissue inhibitor of metalloproteinase-1 antibody on established liver fibrosis in rats. Hepatology (Baltimore, Md.). 40: 1106-15. PMID 15389776 DOI: 10.1002/Hep.20425  1
2004 Magness ST, Jijon H, Van Houten Fisher N, Sharpless NE, Brenner DA, Jobin C. In vivo pattern of lipopolysaccharide and anti-CD3-induced NF-κB activation using a novel gene-targeted enhanced GFP reporter gene mouse Journal of Immunology. 173: 1561-1570. PMID 15265883 DOI: 10.4049/Jimmunol.173.3.1561  1
2004 Black D, Bird MA, Hayden M, Schrum LW, Lange P, Samson C, Hatano E, Rippe RA, Brenner DA, Behrns KE. TNF alpha-induced hepatocyte apoptosis is associated with alterations of the cell cycle and decreased stem loop binding protein. Surgery. 135: 619-28. PMID 15179368 DOI: 10.1016/J.Surg.2003.11.004  1
2004 Black D, Bird MA, Samson CM, Lyman S, Lange PA, Schrum LW, Qian T, Lemasters JJ, Brenner DA, Rippe RA, Behrns KE. Primary cirrhotic hepatocytes resist TGFbeta-induced apoptosis through a ROS-dependent mechanism. Journal of Hepatology. 40: 942-51. PMID 15158334 DOI: 10.1016/J.Jhep.2004.02.031  1
2004 Brenner DA. Gastrointestinal basic science 2002-2003: the year in review. Clinical Gastroenterology and Hepatology. 2: 9-13. PMID 15017626 DOI: 10.1016/S1542-3565(03)00285-4  0.01
2004 Lindquist JN, Parsons CJ, Stefanovic B, Brenner DA. Regulation of alpha1(I) collagen messenger RNA decay by interactions with alphaCP at the 3'-untranslated region. The Journal of Biological Chemistry. 279: 23822-9. PMID 14973140 DOI: 10.1074/Jbc.M314060200  1
2004 Schwabe RF, Uchinami H, Qian T, Bennett BL, Lemasters JJ, Brenner DA. Differential requirement for c-Jun NH2-terminal kinase in TNFalpha- and Fas-mediated apoptosis in hepatocytes. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 720-2. PMID 14766793 DOI: 10.1096/Fj.03-0771Fje  1
2004 Bataller R, Paik YH, Lindquist JN, Lemasters JJ, Brenner DA. Hepatitis C virus core and nonstructural proteins induce fibrogenic effects in hepatic stellate cells. Gastroenterology. 126: 529-40. PMID 14762790 DOI: 10.1053/J.Gastro.2003.11.018  1
2004 Stefanovic B, Stefanovic L, Schnabl B, Bataller R, Brenner DA. TRAM2 protein interacts with endoplasmic reticulum Ca2+ pump Serca2b and is necessary for collagen type I synthesis. Molecular and Cellular Biology. 24: 1758-68. PMID 14749390 DOI: 10.1128/Mcb.24.4.1758-1768.2004  1
2004 Brenner DA. Molecular Pathogenesis of Alcoholic Liver Disease Kanzo. 45. DOI: 10.2957/Kanzo.45.Supplement3_A524  0.01
2004 Brenner DA, Sigmund S. Pathogenesis of alcoholic hepatitis Journal of Gastroenterology and Hepatology. 19. DOI: 10.1111/J.1440-1746.2004.03679.X  0.01
2004 Gäbele E, Reif S, Bataller R, Yata Y, Morris T, Brenner D, Rippe R. Die Rolle von p70S6K bei der Regulation von Proliferation und Kollagenexpression in hepatischen Sternzellen Zeitschrift Fur Gastroenterologie. 42. DOI: 10.1055/S-2004-835762  1
2004 Gäbele E, Reif S, Bataller R, Morris T, Brenner D, Rippe R. Die Rolle von p70S6K bei der Regulation des Zellzyklus und der Kollagenexpression in hepatischen Sternzellen Zeitschrift Fur Gastroenterologie. 42. DOI: 10.1055/S-2004-831797  1
2004 Bataller R, Ros J, Jimenez W, Brenner DA. 308 Anandamide, an endogenous cannabinoid, inhibits contraction, proliferation and migration of human hepatic stellate cells Journal of Hepatology. 40: 94-95. DOI: 10.1016/S0168-8278(04)90308-X  1
2004 Sancho-Bru P, Bataller R, Ginès P, Colmenero J, Khurdayan V, Brenner DA, Arroyo V, Rodés J. 18 Norepinephrine induces inflammatory actions and calcium mobilization in human hepatic stellate cells through alpha receptors Journal of Hepatology. 40: 8. DOI: 10.1016/S0168-8278(04)90018-9  1
2003 Imose M, Nagaki M, Naiki T, Osawa Y, Brenner DA, Asano T, Hayashi H, Kato T, Moriwaki H. Inhibition of nuclear factor κB and phosphatidylinositol 3-kinase/Akt is essential for massive hepatocyte apoptosis induced by tumor necrosis factor α in mice Liver International. 23: 386-396. PMID 14708901 DOI: 10.1034/J.1478-3231.2003.00867.X  1
2003 Bataller R, Schwabe RF, Choi YH, Yang L, Paik YH, Lindquist J, Qian T, Schoonhoven R, Hagedorn CH, Lemasters JJ, Brenner DA. NADPH oxidase signal transduces angiotensin II in hepatic stellate cells and is critical in hepatic fibrosis. The Journal of Clinical Investigation. 112: 1383-94. PMID 14597764 DOI: 10.1172/Jci18212  1
2003 Lehmann TG, Wheeler MD, Froh M, Schwabe RF, Bunzendahl H, Samulski RJ, Lemasters JJ, Brenner DA, Thurman RG. Effects of three superoxide dismutase genes delivered with an adenovirus on graft function after transplantation of fatty livers in the rat. Transplantation. 76: 28-37. PMID 12865782 DOI: 10.1097/01.Tp.0000065299.29900.17  1
2003 Schwabe RF, Bataller R, Brenner DA. Human hepatic stellate cells express CCR5 and RANTES to induce proliferation and migration American Journal of Physiology - Gastrointestinal and Liver Physiology. 285. PMID 12829440 DOI: 10.1152/Ajpgi.00215.2003  1
2003 Kweon YO, Paik YH, Schnabl B, Qian T, Lemasters JJ, Brenner DA. Gliotoxin-mediated apoptosis of activated human hepatic stellate cells. Journal of Hepatology. 39: 38-46. PMID 12821042 DOI: 10.1016/S0168-8278(03)00178-8  1
2003 Bataller R, Gäbele E, Schoonhoven R, Morris T, Lehnert M, Yang L, Brenner DA, Rippe RA. Prolonged infusion of angiotensin II into normal rats induces stellate cell activation and proinflammatory events in liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 285. PMID 12773299 DOI: 10.1152/Ajpgi.00037.2003  1
2003 Paik YH, Schwabe RF, Bataller R, Russo MP, Jobin C, Brenner DA. Toll-like receptor 4 mediates inflammatory signaling by bacterial lipopolysaccharide in human hepatic stellate cells. Hepatology (Baltimore, Md.). 37: 1043-55. PMID 12717385 DOI: 10.1053/jhep.2003.50182  1
2003 Oh KW, Qian T, Brenner DA, Lemasters JJ. Salicylate enhances necrosis and apoptosis mediated by the mitochondrial permeability transition. Toxicological Sciences : An Official Journal of the Society of Toxicology. 73: 44-52. PMID 12700412 DOI: 10.1093/Toxsci/Kfg045  1
2003 Osawa Y, Nagaki M, Banno Y, Brenner DA, Nozawa Y, Moriwaki H, Nakashima S. Expression of the NF-κB Target Gene X-Ray-Inducible Immediate Early Response Factor-1 Short Enhances TNF-α-Induced Hepatocyte Apoptosis by Inhibiting Akt Activation Journal of Immunology. 170: 4053-4060. PMID 12682234 DOI: 10.4049/Jimmunol.170.8.4053  1
2003 Ryen R, Friedman L, Gress F, Kaplan L, Katz PO, Ouyang A, Richter J, Rosen H, Sherman K, Feldman M, Lee SP, Banks PF, Richard Boland C, Ahnen DJ, Burt RW, ... ... Brenner DA, et al. Training the gastroenterologist of the future: The gastroenterology core curriculum Gastroenterology. 124: 1055-1104. PMID 12671902 DOI: 10.1053/Gast.2003.50160  1
2003 Schwabe RF, Bradham CA, Uehara T, Hatano E, Bennett BL, Schoonhoven R, Brenner DA. c-Jun-N-terminal kinase drives cyclin D1 expression and proliferation during liver regeneration. Hepatology (Baltimore, Md.). 37: 824-32. PMID 12668975 DOI: 10.1053/jhep.2003.50135  1
2003 Nishio T, Iimuro Y, Nitta T, Harada N, Yoshida M, Hirose T, Yamamoto N, Morimoto T, Brenner DA, Yamaoka Y. Increased expression of collagenase in the liver induces hepatocyte proliferation with cytoplasmic accumulation of β-catenin in the rat Journal of Hepatology. 38: 468-475. PMID 12663239 DOI: 10.1016/S0168-8278(03)00013-8  1
2003 Schnabl B, Purbeck CA, Choi YH, Hagedorn CH, Brenner D. Replicative senescence of activated human hepatic stellate cells is accompanied by a pronounced inflammatory but less fibrogenic phenotype. Hepatology (Baltimore, Md.). 37: 653-64. PMID 12601363 DOI: 10.1053/Jhep.2003.50097  1
2003 Bataller R, North KE, Brenner DA. Genetic polymorphisms and the progression of liver fibrosis: A critical appraisal Hepatology. 37: 493-503. PMID 12601343 DOI: 10.1053/Jhep.2003.50127  1
2003 Iimuro Y, Nishio T, Morimoto T, Nitta T, Stefanovic B, Choi SK, Brenner DA, Yamaoka Y. Delivery of matrix metalloproteinase-1 attenuates established liver fibrosis in the rat. Gastroenterology. 124: 445-58. PMID 12557150 DOI: 10.1053/Gast.2003.50063  1
2003 Yata Y, Scanga A, Gillan A, Yang L, Reif S, Breindl M, Brenner DA, Rippe RA. DNase I–hypersensitive sites enhance α1(I) collagen gene expression in hepatic stellate cells Hepatology. 37: 267-276. PMID 12540776 DOI: 10.1053/Jhep.2003.50067  1
2003 Reif S, Lang A, Lindquist JN, Yata Y, Gäbele E, Scanga A, Brenner DA, Rippe RA. The role of focal adhesion kinase-phosphatidylinositol 3-kinase-akt signaling in hepatic stellate cell proliferation and type I collagen expression. Journal of Biological Chemistry. 278: 8083-8090. PMID 12502711 DOI: 10.1074/Jbc.M212927200  1
2003 Gäbele E, Brenner DA, Rippe RA. Liver fibrosis: signals leading to the amplification of the fibrogenic hepatic stellate cell. Frontiers in Bioscience. 8. PMID 12456323 DOI: 10.2741/887  1
2003 Stefanovic B, Brenner DA. 5' stem-loop of collagen alpha 1(I) mRNA inhibits translation in vitro but is required for triple helical collagen synthesis in vivo. The Journal of Biological Chemistry. 278: 927-33. PMID 12419812 DOI: 10.1074/Jbc.M209175200  1
2003 Lehnert M, Uehara T, Bradford BU, Lind H, Paik YH, Zhong Z, Brenner DA, Marzi I, Lemasters JJ. Lipopolysaccharide-Binding Protein Modulates Hepatic Damage And Inflammatory Response After Hemorrhagic Shock And Resuscitation.: 81 Shock. 19: 28. DOI: 10.1097/00024382-200306001-00081  1
2003 Brenner DA, Boland CR, Yamada T. Jon Isenberg (1937–2003) Gastroenterology. 125: 1571-1572. DOI: 10.1053/J.Gastro.2003.10.054  0.01
2003 Schwabe RF, Bataller R, Brenner DA, Jijon HB. 1272 Serum amyloid a activates proinflammatory signaling pathways and enhances chemokine secretion in activated human hepatic stellate cells Hepatology. 38: 773-773. DOI: 10.1016/S0270-9139(03)81310-1  1
2003 Osawa Y, Nagaki M, Brenner DA, Moriwaki H. 860 Expression of the NF-kappaB target gene IEX-1S enhances TNF-alpha induced hepatocyte apoptosis by inhibiting AKT activation Hepatology. 38: 574-575. DOI: 10.1016/S0270-9139(03)80902-3  1
2003 Yang L, Bataller R, Coffman TM, Rippe RA, Brenner DA. 365 Attenuated liver fibrosis in angiotensin type 1 receptor deficient mice Hepatology. 38: 336-336. DOI: 10.1016/S0270-9139(03)80408-1  1
2003 Benten D, Kumaran V, Joseph B, Brenner DA, Gupta S. 214 Intrasplenically transplanted human hepatic stellate cells (HSC) engraft and survive in the liver of immunodeficient mice for prolonged periods Hepatology. 38: 259-259. DOI: 10.1016/S0270-9139(03)80257-4  0.01
2003 Imose M, Nagaki M, Naiki T, Osawa Y, Brenner D, Asano T, Hayashi H, Imao M, Takai S, Kimura K. 180 Inhibition of nuclear factor-κB and phosphatidylinositol 3-kinase/AKT is essential for massive hepatocyte apoptosis induced by tumor necrosis factor α in mice Hepatology. 38: 242-242. DOI: 10.1016/S0270-9139(03)80223-9  1
2003 Rippe RA, Lindquist J, Bataller R, Morris T, Wheeler MD, Brenner DA. 142 Inhibition of phosphatidylinositol 3-kinase activity attenuates the development of experimentally induced liver fibrosis Hepatology. 38: 224-224. DOI: 10.1016/S0270-9139(03)80185-4  1
2003 Brown RS, Brenner DA. MELD and the practicing gastroenterologist. Gastroenterology. 125: 1009-1009. DOI: 10.1016/J.Gastro.2003.08.008  0.01
2002 Lemasters JJ, Qian T, He L, Kim JS, Elmore SP, Cascio WE, Brenner DA. Role of mitochondrial inner membrane permeabilization in necrotic cell death, apoptosis, and autophagy. Antioxidants & Redox Signaling. 4: 769-81. PMID 12470504 DOI: 10.1089/152308602760598918  1
2002 Osawa Y, Nagaki M, Banno Y, Brenner DA, Asano T, Nozawa Y, Moriwaki H, Nakashima S. Tumor Necrosis Factor Alpha-Induced Interleukin-8 Production via NF-κB and Phosphatidylinositol 3-Kinase/Akt Pathways Inhibits Cell Apoptosis in Human Hepatocytes Infection and Immunity. 70: 6294-6301. PMID 12379708 DOI: 10.1128/Iai.70.11.6294-6301.2002  1
2002 Samson CM, Schrum LW, Bird MA, Lange PA, Brenner DA, Rippe RA, Behrns KE. Transforming growth factor-β1 induces hepatocyte apoptosis by a c-Jun independent mechanism Surgery. 132: 441-449. PMID 12324757 DOI: 10.1067/Msy.2002.125321  1
2002 Brenner DA, Camilleri M. Joint statement on missions and submissions of papers to AGA journals. Gastroenterology. 123: 877-878. PMID 12198713 DOI: 10.1053/Gast.2002.35760  0.01
2002 Liedtke C, Plümpe J, Kubicka S, Bradham CA, Manns MP, Brenner DA, Trautwein C. Jun kinase modulates tumor necrosis factor-dependent apoptosis in liver cells. Hepatology (Baltimore, Md.). 36: 315-25. PMID 12143039 DOI: 10.1053/Jhep.2002.34615  1
2002 Schwabe RF, Brenner DA. Role of glycogen synthase kinase-3 in TNF-α-induced NF-κB activation and apoptosis in hepatocytes American Journal of Physiology-Gastrointestinal and Liver Physiology. 283. PMID 12065308 DOI: 10.1152/Ajpgi.00016.2002  1
2002 Russo MP, Bennett BL, Manning AM, Brenner DA, Jobin C. Differential requirement for NF-kappaB-inducing kinase in the induction of NF-kappaB by IL-1beta, TNF-alpha, and Fas. American Journal of Physiology. Cell Physiology. 283: C347-57. PMID 12055104 DOI: 10.1152/Ajpcell.00166.2001  1
2002 Schnabl B, Choi YH, Olsen JC, Hagedorn CH, Brenner DA. Immortal activated human hepatic stellate cells generated by ectopic telomerase expression. Laboratory Investigation; a Journal of Technical Methods and Pathology. 82: 323-33. PMID 11896211 DOI: 10.1038/Labinvest.3780426  1
2002 Stefanovic B, Schnabl B, Brenner DA. Inhibition of collagen alpha 1(I) expression by the 5' stem-loop as a molecular decoy. The Journal of Biological Chemistry. 277: 18229-37. PMID 11889120 DOI: 10.1074/Jbc.M108065200  1
2002 Brenner DA, Zimmer D. Gastro-Central, one year later Gastroenterology. 123: 5-6. DOI: 10.1053/Gast.2002.34836  0.01
2002 Sanz S, Rodriguez-Ortigosa CM, Lund K, Brenner DA, Prieto J. Insulin-like growth factor type-I (IGF-I) modulates the inflammatory response within the liver Journal of Hepatology. 36: 10. DOI: 10.1016/S0168-8278(02)80026-5  1
2002 Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burchardt ER, Schoonhoven R, Brenner DA, Fried MW. Erratum: Decreasing fibrogenesis. An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B (Journal of Hepatology (2001) 35 (749-755) PII:S0168827801002185) Journal of Hepatology. 36. DOI: 10.1016/S0168-8278(02)00116-2  1
2001 Kweon YO, Goodman ZD, Dienstag JL, Schiff ER, Brown NA, Burkhardt E, Schoonhoven R, Brenner DA, Fried MW. Decreasing fibrogenesis: An immunohistochemical study of paired liver biopsies following lamivudine therapy for chronic hepatitis B Journal of Hepatology. 35: 749-755. PMID 11738102 DOI: 10.1016/S0168-8278(01)00218-5  1
2001 Hatano E, Brenner DA. Akt protects mouse hepatocytes from TNF-α- and Fas-mediated apoptosis through NK-κB activation American Journal of Physiology - Gastrointestinal and Liver Physiology. 281. PMID 11705740 DOI: 10.1152/Ajpgi.2001.281.6.G1357  1
2001 Schnabl B, Bradham CA, Bennett BL, Manning AM, Stefanovic B, Brenner DA. TAK1/JNK and p38 have opposite effects on rat hepatic stellate cells. Hepatology (Baltimore, Md.). 34: 953-63. PMID 11679966 DOI: 10.1053/Jhep.2001.28790  1
2001 Bradham CA, Hatano E, Brenner DA. Dominant-negative TAK1 induces c-Myc and G(0) exit in liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 281: G1279-89. PMID 11668037 DOI: 10.1152/Ajpgi.2001.281.5.G1279  1
2001 Bataller R, Brenner DA. Hepatic stellate cells as a target for the treatment of liver fibrosis Seminars in Liver Disease. 21: 437-451. PMID 11586471 DOI: 10.1055/S-2001-17558  1
2001 Schnabl B, Kweon YO, Frederick JP, Wang XF, Rippe RA, Brenner DA. The role of Smad3 in mediating mouse hepatic stellate cell activation. Hepatology (Baltimore, Md.). 34: 89-100. PMID 11431738 DOI: 10.1053/Jhep.2001.25349  1
2001 Osawa Y, Banno Y, Nagaki M, Brenner DA, Naiki T, Nozawa Y, Nakashima S, Moriwaki H. TNF-α-Induced Sphingosine 1-Phosphate Inhibits Apoptosis Through a Phosphatidylinositol 3-Kinase/Akt Pathway in Human Hepatocytes Journal of Immunology. 167: 173-180. PMID 11418646 DOI: 10.4049/Jimmunol.167.1.173  1
2001 Schwabe RF, Schnabl B, Kweon YO, Brenner DA. CD40 activates NF-κB and c-Jun N-terminal kinase and enhances chemokine secretion on activated human hepatic stellate cells Journal of Immunology. 166: 6812-6819. PMID 11359840 DOI: 10.4049/Jimmunol.166.11.6812  1
2001 Kono H, Nakagami M, Rusyn I, Connor HD, Stefanovic B, Brenner DA, Mason RP, Arteel GE, Thurman RG. Development of an animal model of chronic alcohol-induced pancreatitis in the rat American Journal of Physiology - Gastrointestinal and Liver Physiology. 280. PMID 11352811 DOI: 10.1152/Ajpgi.2001.280.6.G1178  1
2001 Hatano E, Bennett BL, Manning AM, Qian T, Lemasters JJ, Brenner DA. NF-kappaB stimulates inducible nitric oxide synthase to protect mouse hepatocytes from TNF-alpha- and Fas-mediated apoptosis. Gastroenterology. 120: 1251-62. PMID 11266388 DOI: 10.1053/Gast.2001.23239  1
2001 Rippe RA, Brenner DA, Tugores A. Techniques to Measure Nucleic Acid-Protein Binding and Specificity Methods of Molecular Biology. 160: 459-479. PMID 11265303 DOI: 10.1385/1-59259-233-3:459  1
2001 Schwabe RF, Bennett BL, Manning AM, Brenner DA. Differential role of IκB kinase 1 and 2 in primary rat hepatocytes Hepatology. 33: 81-90. PMID 11124824 DOI: 10.1053/Jhep.2001.20799  1
2001 Schrum LW, Bird MA, Salcher O, Burchardt ER, Grisham JW, Brenner DA, Rippe RA, Behrns KE. Autocrine expression of activated transforming growth factor-beta(1) induces apoptosis in normal rat liver. American Journal of Physiology. Gastrointestinal and Liver Physiology. 280: G139-48. PMID 11123207 DOI: 10.1152/Ajpgi.2001.280.1.G139  1
2001 Nishiura T, Nishimura T, deSerres S, Nakagawa T, Oi I, Brenner DA, Meyer AA. Activation of Stat3 in the Liver after Burn Injury in Mice: 150. Journal of Burn Care & Rehabilitation. 22. DOI: 10.1097/00004630-200103002-00150  1
2001 Magness ST, Russo MP, Brenner DA, Sartor RB, Jobin C. Generation of an NF-κB responsive, GFP-reporter gene mouse using a single copy HPRT gene-targeting system Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)81504-1  1
2001 Dacosta CM, Simmons JG, Fuller CR, Williams KL, Breindl M, Rippe RA, Brenner DA, Pucilowska JB, Lund PK. Collagen promoter-GFP transgenic mice provide a model to study collagen gene expression during experimental intestinal inflammation and injury in vivo and in vitro Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80663-4  1
2001 Reif S, Scanga AE, Brenner DA, Rippe RA. The role of AKT in hepatic stellate cell activation Gastroenterology. 120. DOI: 10.1016/S0016-5085(08)80132-1  1
2000 Lang A, Schrum LW, Schoonhoven R, Tuvia S, Solís-Herruzo JA, Tsukamoto H, Brenner DA, Rippe RA. Expression of small heat shock protein alphaB-crystallin is induced after hepatic stellate cell activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 279: G1333-42. PMID 11093957 DOI: 10.1152/Ajpgi.2000.279.6.G1333  1
2000 Nagaki M, Naiki T, Brenner DA, Osawa Y, Imose M, Hayashi H, Banno Y, Nakashima S, Moriwaki H. Tumor necrosis factor α prevents tumor necrosis factor receptor—mediated mouse hepatocyte apoptosis, but not fas‐mediated apoptosis: Role of nuclear factor‐κB Hepatology. 32: 1272-1279. PMID 11093734 DOI: 10.1053/Jhep.2000.20239  1
2000 Lehmann TG, Wheeler MD, Schwabe RF, Connor HD, Schoonhoven R, Bunzendahl H, Brenner DA, Jude Samulski R, Zhong Z, Thurman RG. Gene delivery of Cu/Zn-superoxide dismutase improves graft function after transplantation of fatty livers in the rat. Hepatology (Baltimore, Md.). 32: 1255-64. PMID 11093732 DOI: 10.1053/Jhep.2000.19814  1
2000 Lindquist JN, Kauschke SG, Stefanovic B, Burchardt ER, Brenner DA. Characterization of the interaction between αCP2 and the 3'-untranslated region of collagen α1(I) mRNA Nucleic Acids Research. 28: 4306-4316. PMID 11058131 DOI: 10.1093/Nar/28.21.4306  1
2000 Brenner DA. Moderate alcohol drinking: Effects on the heart and liver☆ Gastroenterology. 119: 1399-1401. PMID 11054400 DOI: 10.1053/Gast.2000.20206  0.01
2000 Streetz K, Leifeld L, Grundmann D, Ramakers J, Eckert K, Spengler U, Brenner D, Manns M, Trautwein C. Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure Gastroenterology. 119: 446-460. PMID 10930380 DOI: 10.1053/Gast.2000.9364  1
2000 Lang A, Schoonhoven R, Tuvia S, Brenner DA, Rippe RA. Nuclear factor κB in proliferation, activation, and apoptosis in rat hepatic stellate cells Journal of Hepatology. 33: 49-58. PMID 10905586 DOI: 10.1016/S0168-8278(00)80159-2  1
2000 Xu LH, Yang X, Bradham CA, Brenner DA, Baldwin AS, Craven RJ, Cance WG. The focal adhesion kinase suppresses transformation-associated, anchorage-independent apoptosis in human breast cancer cells. Involvement of death receptor-related signaling pathways. The Journal of Biological Chemistry. 275: 30597-604. PMID 10899173 DOI: 10.1074/Jbc.M910027199  1
2000 Enomoto N, Ikejima K, Yamashina S, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Schemmer P, Bradford BU, Rivera CA, Zhong Z, Thurman RG. Kupffer cell-derived prostaglandin E2 is involved in alcohol-induced fat accumulation in rat liver American Journal of Physiology - Gastrointestinal and Liver Physiology. 279. PMID 10898751 DOI: 10.1152/Ajpgi.2000.279.1.G100  1
2000 Böcker U, Schottelius A, Watson JM, Holt L, Licato LL, Brenner DA, Sartor RB, Jobin C. Cellular Differentiation Causes a Selective Down-regulation of Interleukin (IL)-1β-mediated NF-κB Activation and IL-8 Gene Expression in Intestinal Epithelial Cells Journal of Biological Chemistry. 275: 12207-12213. PMID 10766857 DOI: 10.1074/Jbc.275.16.12207  1
2000 Hatano E, Bradham CA, Stark A, Iimuro Y, Lemasters JJ, Brenner DA. The mitochondrial permeability transition augments Fas-induced apoptosis in mouse hepatocytes Journal of Biological Chemistry. 275: 11814-11823. PMID 10766806 DOI: 10.1074/Jbc.275.16.11814  1
2000 Enomoto N, Ikejima K, Bradford BU, Rivera CA, Kono H, Goto M, Yamashina S, Schemmer P, Kitamura T, Oide H, Takei Y, Hirose M, Shimizu H, Miyazaki A, Brenner DA, et al. Role of Kupffer cells and gut-derived endotoxins in alcoholic liver injury. Journal of Gastroenterology and Hepatology. 15: D20-5. PMID 10759216 DOI: 10.1046/J.1440-1746.2000.02179.X  1
2000 Nishiura T, Nishimura T, deSerres S, Godfrey V, Bradham CA, Nakagawa T, Brenner DA, Meyer AA. Gene expression and cytokine and enzyme activation in the liver after a burn injury. The Journal of Burn Care & Rehabilitation. 21: 135-41. PMID 10752746 DOI: 10.1097/00004630-200021020-00009  1
2000 Iimuro Y, Bradford BU, Yamashina S, Rusyn I, Nakagami M, Enomoto N, Kono H, Frey W, Forman D, Brenner D, Thurman RG. The glutathione precursor L-2-oxothiazolidine-4-carboxylic acid protects against liver injury due to chronic enteral ethanol exposure in the rat Hepatology. 31: 391-398. PMID 10655262 DOI: 10.1002/Hep.510310219  1
2000 Nishimura T, Nishiura T, deserres S, Nakagawa T, Brenner DA, Meyer AA. Impact of burn injury on hepatic TGF-β1 expression and plasma TGF-β1 levels Journal of Trauma-Injury Infection and Critical Care. 48: 39-44. PMID 10647563 DOI: 10.1097/00005373-200001000-00007  1
2000 Schrum LW, Black D, Iimuro Y, Rippe RA, Brenner DA, Behrns KE. c-Jun does not mediate hepatocyte apoptosis following NFkappaB inhibition and partial hepatectomy. The Journal of Surgical Research. 88: 142-9. PMID 10644480 DOI: 10.1006/Jsre.1999.5784  1
2000 Rhoads JM, Argenzio RA, Chen W, Graves LM, Licato LL, Blikslager AT, Smith J, Gatzy J, Brenner DA. Glutamine metabolism stimulates intestinal cell MAPKs by a CAMP- inhibitable, Raf-independent mechanism Gastroenterology. 118: 90-100. PMID 10611157 DOI: 10.1016/S0016-5085(00)70417-3  1
2000 Stefanovic B, Lindquist J, Brenner DA. The 5' stem-loop regulates expression of collagen α1(I) mRNA in mouse fibroblasts cultured in a three-dimensional matrix Nucleic Acids Research. 28: 641-647. PMID 10606666 DOI: 10.1093/Nar/28.2.641  1
2000 Magness ST, Tugores A, Brenner DA. Analysis of ferrochelatase expression during hematopoietic development of embryonic stem cells Blood. 95: 3568-3577. DOI: 10.1182/Blood.V95.11.3568.011K40_3568_3577  1
2000 Pümpe J, Liedtke C, Bradham CA, Brenner DA, Manns MP, Trautwein C. TNFα-dependent Jun kinase activity modulates apoptosis in humanhepatoma cells Journal of Hepatology. 32: 76. DOI: 10.1016/S0168-8278(00)80622-4  1
2000 Bradham CA, Hatano E, Bennett BL, Manning AM, Brenner DA. JNK activation is required for hepatocyte proliferation and cyclin D1 expression following partial hepatectomy in rats Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86236-8  1
2000 Liu SL, Sanz S, Pucilowska JB, Fuller CR, Prieto J, Brenner DA, Fagin JA, Lund PK. Stellate cell specific overexpression of IGF-I reduces acute liver damage induced by carbon-tetrachloride in vivo Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86205-8  1
2000 Schwabe RF, Schnabl B, Brenner DA. CD40 activates NFKB and JNK and enhances IL-8 secretion on human hepatic myofibroblasts Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86204-6  1
2000 Schnabl B, Lim S, Kweon Y, Wang X, Rippe RA, Brenner DA. The in vivo role of Sma3 in mediating CCl4 induced liver fibrosis Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)86095-3  1
2000 Schwabe RF, Bennett BL, Manning AM, Brenner DA. Differential function of IKB kinase 1 and 2 in primary hepatocytes Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85771-6  1
2000 Hatano E, Bradham CA, Mignon A, Brenner DA. Protective pathways in TNFA - and fas-mediated apoptosis in hepatocytes Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)85712-1  1
2000 Schwabe RF, Russo MP, Bennett BL, Manning AM, Brenner DA, Sartor RB, Jobin C. Adenovlral (AD5) delivery of wild type IkB kinase B(IKKB) but not ad5ikka restored the defective IKB/NF-KB signaling pathway in HT-29 cells Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84594-1  1
2000 Russo MP, Brandham CA, Bennett BL, Manning AM, Brenner DA, Jobin C. IKB kinase B(IKKB), but not NF-KB-inducing kinase (NIK) or IKKA, represents a therapeutic target for modulation of fas, IL-1B and TNFA-mediated NF-KB activation in intestinal epithelial cells (IEC) Gastroenterology. 118. DOI: 10.1016/S0016-5085(00)84486-8  1
1999 Lemasters JJ, Qian T, Trost LC, Herman B, Cascio WE, Bradham CA, Brenner DA, Nieminen AL. Confocal microscopy of the mitochondrial permeability transition in necrotic and apoptotic cell death. Biochemical Society Symposium. 66: 205-22. PMID 10989668 DOI: 10.1042/Bss0660205  1
1999 Lemasters JJ, Qian T, Bradham CA, Brenner DA, Cascio WE, Trost LC, Nishimura Y, Nieminen AL, Herman B. Mitochondrial dysfunction in the pathogenesis of necrotic and apoptotic cell death. Journal of Bioenergetics and Biomembranes. 31: 305-19. PMID 10665521 DOI: 10.1023/A:1005419617371  1
1999 Rusyn I, Bradham CA, Cohn L, Schoonhoven R, Swenberg JA, Brenner DA, Thurman RG. Corn oil rapidly activates nuclear factor-kappaB in hepatic Kupffer cells by oxidant-dependent mechanisms. Carcinogenesis. 20: 2095-100. PMID 10545411 DOI: 10.1093/Carcin/20.11.2095  1
1999 Rippe RA, Schrum LW, Stefanovic B, Solís-Herruzo JA, Brenner DA. NF-kappaB inhibits expression of the alpha1(I) collagen gene. Dna and Cell Biology. 18: 751-61. PMID 10541434 DOI: 10.1089/104454999314890  1
1999 Solís-Herruzo JA, Rippe RA, Schrum LW, de La Torre P, García I, Jeffrey JJ, Muñoz-Yagüe T, Brenner DA. Interleukin-6 increases rat metalloproteinase-13 gene expression through stimulation of activator protein 1 transcription factor in cultured fibroblasts. The Journal of Biological Chemistry. 274: 30919-26. PMID 10521486 DOI: 10.1074/Jbc.274.43.30919  1
1999 Enomoto N, Yamashina S, Schemmer P, Rivera CA, Bradford BU, Enomoto A, Brenner DA, Thurman RG. Estriol sensitizes rat Kupffer cells via gut-derived endotoxin American Journal of Physiology - Gastrointestinal and Liver Physiology. 277. PMID 10484393 DOI: 10.1152/Ajpgi.1999.277.3.G671  1
1999 Uzawa K, Grzesik WJ, Nishiura T, Kuznetsov SA, Robey PG, Brenner DA, Yamauchi M. Differential expression of human lysyl hydroxylase genes, lysine hydroxylation, and cross-linking of type I collagen during osteoblastic differentiation in vitro Journal of Bone and Mineral Research. 14: 1272-1280. PMID 10457259 DOI: 10.1359/Jbmr.1999.14.8.1272  1
1999 Batra RK, Guttridge DC, Brenner DA, Dubinett SM, Baldwin AS, Boucher RC. IkappaBalpha gene transfer is cytotoxic to squamous-cell lung cancer cells and sensitizes them to tumor necrosis factor-alpha-mediated cell death. American Journal of Respiratory Cell and Molecular Biology. 21: 238-45. PMID 10423407 DOI: 10.1165/Ajrcmb.21.2.3470  1
1999 Enomoto N, Yamashina S, Kono H, Schemmer P, Rivera CA, Enomoto A, Nishiura T, Nishimura T, Brenner DA, Thurman RG. Development of a new, simple rat model of early alcohol-induced liver injury based on sensitization of Kupffer cells Hepatology. 29: 1680-1689. PMID 10347108 DOI: 10.1002/Hep.510290633  1
1999 Stefanovic B, Hellerbrand C, Brenner DA. Regulatory role of the conserved stem-loop structure at the 5' end of collagen α1(I) mRNA Molecular and Cellular Biology. 19: 4334-4342. PMID 10330174 DOI: 10.1128/Mcb.19.6.4334  1
1999 Magness ST, Brenner DA. Targeted disruption of the mouse ferrochelatase gene producing an exon 10 deletion Biochimica Et Biophysica Acta. 1453: 161-174. PMID 9989256 DOI: 10.1016/S0925-4439(98)00096-9  1
1999 Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER, Brenner DA. The role of TGFβ1 in initiating hepatic stellate cell activation in vivo Journal of Hepatology. 30: 77-87. PMID 9927153 DOI: 10.1016/S0168-8278(99)80010-5  1
1998 Bradham CA, Plümpe J, Manns MP, Brenner DA, Trautwein C. I. TNF-induced liver injury. American Journal of Physiology. Gastrointestinal and Liver Physiology. 275: G387-G392. PMID 29585442 DOI: 10.1152/Ajpgi.1998.275.3.G387  1
1998 Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, Czaja MJ. NF-κB inactivation converts a hepatocyte cell line TNF-α response from proliferation to apoptosis. American Journal of Physiology. Cell Physiology. 275: C1058-C1066. PMID 29585321 DOI: 10.1152/ajpcell.1998.275.4.C1058  1
1998 Ikejima K, Enomoto N, Iimuro Y, Ikejima A, Fang D, Xu J, Forman DT, Brenner DA, Thurman RG. Estrogen increases sensitivity of hepatic Kupffer cells to endotoxin. American Journal of Physiology. Gastrointestinal and Liver Physiology. 274: G669-G676. PMID 29585282 DOI: 10.1152/Ajpgi.1998.274.4.G669  1
1998 Thurman RG, Bradford BU, Iimuro Y, Knecht KT, Arteel GE, Yin M, Connor HD, Wall C, Raleigh JA, Frankenberg MV, Adachi Y, Forman DT, Brenner D, Kadiiska M, Mason RP. The role of gut-derived bacterial toxins and free radicals in alcohol-induced liver injury. Journal of Gastroenterology and Hepatology. 13: S39-S50. PMID 28976690 DOI: 10.1111/Jgh.1998.13.S1.39  1
1998 Brenner DA. Signal transduction during liver regeneration. Journal of Gastroenterology and Hepatology. 13. PMID 28976689 DOI: 10.1111/Jgh.1998.13.S1.93  0.01
1998 Scarlett YV, Brenner DA, Bloomer JR. Hepatic porphyrias. Clinics in Liver Disease. 2: 77-102, vi. PMID 15560047 DOI: 10.1016/s1089-3261(05)70365-2  1
1998 Lemasters JJ, Qian T, Elmore SP, Trost LC, Nishimura Y, Herman B, Bradham CA, Brenner DA, Nieminen AL. Confocal microscopy of the mitochondrial permeability transition in necrotic cell killing, apoptosis and autophagy. Biofactors (Oxford, England). 8: 283-5. PMID 9914830 DOI: 10.1002/Biof.5520080316  1
1998 Bradham CA, Qian T, Streetz K, Trautwein C, Brenner DA, Lemasters JJ. The mitochondrial permeability transition is required for tumor necrosis factor alpha-mediated apoptosis and cytochrome c release. Molecular and Cellular Biology. 18: 6353-64. PMID 9774651 DOI: 10.1128/Mcb.18.11.6353  1
1998 Xu Y, Bialik S, Jones BE, Iimuro Y, Kitsis RN, Srinivasan A, Brenner DA, Czaja MJ. NF-kappaB inactivation converts a hepatocyte cell line TNF-alpha response from proliferation to apoptosis. The American Journal of Physiology. 275: C1058-66. PMID 9755059 DOI: 10.1152/Ajpcell.1998.275.4.C1058  1
1998 Lemasters JJ, Nieminen AL, Qian T, Trost LC, Elmore SP, Nishimura Y, Crowe RA, Cascio WE, Bradham CA, Brenner DA, Herman B. The mitochondrial permeability transition in cell death: a common mechanism in necrosis, apoptosis and autophagy. Biochimica Et Biophysica Acta. 1366: 177-96. PMID 9714796 DOI: 10.1016/S0005-2728(98)00112-1  1
1998 Jobin C, Hellerbrand C, Licato LL, Brenner DA, Sartor RB. Mediation by NF-κB of cytokine induced expression of intercellular adhesion molecule 1 (ICAM-1) in an intestinal epithelial cell line, a process blocked by proteasome inhibitors Gut. 42: 779-787. PMID 9691914 DOI: 10.1136/Gut.42.6.779  1
1998 Licato LL, Brenner DA. Analysis of signaling protein kinases in human colon or colorectal carcinomas Digestive Diseases and Sciences. 43: 1454-1464. PMID 9690379 DOI: 10.1023/A:1018894227169  1
1998 Hellerbrand C, Jobin C, Licato LL, Sartor RB, Brenner DA. Cytokines induce NF-κB in activated but not in quiescent rat hepatic stellate cells American Journal of Physiology-Gastrointestinal and Liver Physiology. 275. PMID 9688654 DOI: 10.1152/Ajpgi.1998.275.2.G269  1
1998 Bloomer J, Bruzzone C, Zhu L, Scarlett Y, Magness S, Brenner D. Molecular defects in ferrochelatase in patients with protoporphyria requiring liver transplantation. The Journal of Clinical Investigation. 102: 107-14. PMID 9649563 DOI: 10.1172/Jci1347  0.01
1998 Trautwein C, Rakemann T, Brenner DA, Streetz K, Licato L, Manns MP, Tiegs G. Concanavalin A—induced liver cell damage: Activation of intracellular pathways triggered by tumor necrosis factor in mice Gastroenterology. 114: 1035-1045. PMID 9558294 DOI: 10.1016/S0016-5085(98)70324-5  1
1998 Iimuro Y, Nishiura T, Hellerbrand C, Behrns KE, Schoonhoven R, Grisham JW, Brenner DA. NFkappaB prevents apoptosis and liver dysfunction during liver regeneration. Journal of Clinical Investigation. 101: 802-811. PMID 9466975 DOI: 10.1172/Jci483  1
1998 Magness ST, Tugores A, Diala ES, Brenner DA. Analysis of the Human Ferrochelatase Promoter in Transgenic Mice Blood. 92: 320-328. DOI: 10.1182/Blood.V92.1.320.413K25_320_328  1
1998 Nishiura T, Nishimura T, deSerres S, Nakagawa T, Brenner DA, Meyer AA. Gene Expression, Cytokine and Enzyme Activation in the Liver after Burn Injury: 206. Journal of Burn Care & Rehabilitation. 19. DOI: 10.1097/00004630-199801001-00206  1
1998 Hellerbrand C, Jobin C, Licato LL, Sartor RB, Brenner DA. NFκB mediates LPS-induced expression of IL-6 and ICAM-1 in activated hepatic stellate cells, a process blocked by proteasome inhibitors Journal of Hepatology. 28: 49. DOI: 10.1016/S0168-8278(98)80398-X  1
1998 Hellerbrand C, Jobin C, Limuro Y, Licato L, Sartor R, Brenner D. Inhibition of proinllammatory molecule expression by adenovirus-mediated expression of an NFkB super repressor in activated hepatic stellate cells Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)85087-7  1
1998 Jobin C, Klein J, Brandham C, Streetz K, Brenner DA, Sartor RB. TNFα signaling blockade by a dominant-negative TRAF-2 delivered by adenoviral vector inhibits NF-κB and JNK activation and IL-8 expression in human intestinal epithelial cells Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)84089-4  1
1998 Böcker U, Jobin C, Holt L, Licato L, Brenner D, Sartor RB. Intestinal epithelial cell differentiation impairs chemokine expression induced by the interleukin-1 signalling pathway Gastroenterology. 114. DOI: 10.1016/S0016-5085(98)83809-2  1
1997 Xu Y, Bradham C, Brenner DA, Czaja MJ. Hydrogen peroxide-induced liver cell necrosis is dependent on AP-1 activation. American Journal of Physiology. Gastrointestinal and Liver Physiology. 273: G795-G803. PMID 29585127 DOI: 10.1152/Ajpgi.1997.273.4.G795  1
1997 Stefanovic B, Hellerbrand C, Holcik M, Briendl M, Liebhaber SA, Brenner DA. Posttranscriptional regulation of collagen α1(I) mRNA in hepatic stellate cells Molecular and Cellular Biology. 17: 5201-5209. PMID 9271398 DOI: 10.1128/Mcb.17.9.5201  1
1997 Bradham CA, Stachlewitz RF, Gao W, Qian T, Jayadev S, Jenkins G, Hannun Y, Lemasters JJ, Thurman RG, Brenner DA. Reperfusion after liver transplantation in rats differentially activates the mitogen-activated protein kinases. Hepatology (Baltimore, Md.). 25: 1128-35. PMID 9141429 DOI: 10.1002/Hep.510250514  1
1997 Rippe RA, Umezawa A, Kimball JP, Breindl M, Brenner DA. Binding of upstream stimulatory factor to an E-box in the 3'-flanking region stimulates alpha1(I) collagen gene transcription. The Journal of Biological Chemistry. 272: 1753-60. PMID 8999857 DOI: 10.1074/Jbc.272.3.1753  1
1996 Westwick JK, Fleckenstein J, Yin M, Yang SQ, Bradham CA, Brenner DA, Diehl AM. Differential regulation of hepatocyte DNA synthesis by cAMP in vitro in vivo American Journal of Physiology-Gastrointestinal and Liver Physiology. 271. PMID 8944691 DOI: 10.1152/Ajpgi.1996.271.5.G780  1
1996 Hellerbrand C, Wang SC, Tsukamoto H, Brenner DA, Rippe RA. Expression of intracellular adhesion molecule 1 by activated hepatic stellate cells. Hepatology. 24: 670-676. PMID 8781341 DOI: 10.1002/Hep.510240333  1
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