| Year |
Citation |
Score |
| 2023 |
Yamamoto M, Ito Y, Fukui M, Otake K, Shoji Y, Kitao T, Shirahase H, Hinoi E. Osteogenic Effects of KY-054, a Novel Coumarin Derivative on Femur Cortical Bone in Ovariectomized Female Rats. Biological & Pharmaceutical Bulletin. 46: 1435-1443. PMID 37779045 DOI: 10.1248/bpb.b23-00324 |
0.319 |
|
| 2023 |
Park G, Fukasawa K, Horie T, Masuo Y, Inaba Y, Tatsuno T, Yamada T, Tokumura K, Iwahashi S, Iezaki T, Kaneda K, Kato Y, Ishigaki Y, Mieda M, Tanaka T, ... ... Hinoi E, et al. L-type amino acid transporter 1 in hypothalamic neurons in mice maintains energy and bone homeostasis. Jci Insight. PMID 36862514 DOI: 10.1172/jci.insight.154925 |
0.334 |
|
| 2022 |
Yamada T, Fukasawa K, Horie T, Kadota T, Lyu J, Tokumura K, Ochiai S, Iwahashi S, Suzuki A, Park G, Ueda R, Yamamoto M, Kitao T, Shirahase H, Ochi H, ... ... Hinoi E, et al. The role of CDK8 in mesenchymal stem cells in controlling osteoclastogenesis and bone homeostasis. Stem Cell Reports. PMID 35777359 DOI: 10.1016/j.stemcr.2022.06.001 |
0.352 |
|
| 2022 |
Horie T, Fukasawa K, Yamada T, Mizuno S, Iezaki T, Tokumura K, Iwahashi S, Sakai S, Suzuki A, Kubo T, Osumi R, Tomizawa A, Ochi H, Sato S, Kaneda K, ... ... Hinoi E, et al. Erk5 in Bone Marrow Mesenchymal Stem Cells Regulates Bone Homeostasis by Preventing Osteogenesis in Adulthood. Stem Cells (Dayton, Ohio). PMID 35304894 DOI: 10.1093/stmcls/sxac011 |
0.372 |
|
| 2021 |
Iezaki T, Hinoi E. [Phosphorylation of Smurf2 at Thr249 by Erk5 regulates TGF-β signaling]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 156: 271-274. PMID 34470930 DOI: 10.1254/fpj.21029 |
0.325 |
|
| 2021 |
Ochiai S, Tokumura K, Park G, Ozaki K, Horie T, Yamada T, Iwahashi S, Ohta K, Fusawa H, Okayama Y, Kaneda K, Iezaki T, Hinoi E. Daily oral supplementation of Hochu-Ekki-To prevents osteoclastic activation and bone loss in ovariectomized mice. Journal of Pharmacological Sciences. 145: 1-5. PMID 33357767 DOI: 10.1016/j.jphs.2020.09.007 |
0.347 |
|
| 2019 |
Horie T, Park G, Inaba Y, Hashiuchi E, Iezaki T, Tokumura K, Fukasawa K, Yamada T, Hiraiwa M, Kitaguchi Y, Kamada H, Kaneda K, Tanaka T, Inoue H, Hinoi E. MAPK Erk5 in leptin receptor-expressing neurons controls body weight and systemic energy homeostasis in female mice. Endocrinology. PMID 31555819 DOI: 10.1210/En.2019-00090 |
0.377 |
|
| 2019 |
Tosa I, Yamada D, Yasumatsu M, Hinoi E, Ono M, Oohashi T, Kuboki T, Takarada T. Postnatal Runx2 deletion leads to low bone mass and adipocyte accumulation in mice bone tissues. Biochemical and Biophysical Research Communications. PMID 31300199 DOI: 10.1016/J.Bbrc.2019.07.014 |
0.465 |
|
| 2019 |
Ozaki K, Yamada T, Horie T, Ishizaki A, Hiraiwa M, Iezaki T, Park G, Fukasawa K, Kamada H, Tokumura K, Motono M, Kaneda K, Ogawa K, Ochi H, Sato S, ... ... Hinoi E, et al. The L-type amino acid transporter LAT1 inhibits osteoclastogenesis and maintains bone homeostasis through the mTORC1 pathway. Science Signaling. 12. PMID 31289211 DOI: 10.1126/Scisignal.Aaw3921 |
0.481 |
|
| 2019 |
Yamada T, Park G, Node J, Ozaki K, Hiraiwa M, Kitaguchi Y, Kaneda K, Hiramoto S, Hinoi E. Daily intake of polyamine-rich prevents osteoclastic activation and bone loss in ovariectomized mice. Food Science and Biotechnology. 28: 1241-1245. PMID 31275725 DOI: 10.1007/S10068-019-00561-4 |
0.441 |
|
| 2019 |
Hiraiwa M, Ozaki K, Yamada T, Iezaki T, Park G, Fukasawa K, Horie T, Kamada H, Tokumura K, Motono M, Kaneda K, Hinoi E. mTORC1 Activation in Osteoclasts Prevents Bone Loss in a Mouse Model of Osteoporosis. Frontiers in Pharmacology. 10: 684. PMID 31263418 DOI: 10.3389/Fphar.2019.00684 |
0.472 |
|
| 2019 |
Onishi Y, Hiraiwa M, Kamada H, Iezaki T, Yamada T, Kaneda K, Hinoi E. Hypoxia affects Slc7a5 expression through HIF-2α in differentiated neuronal cells. Febs Open Bio. 9: 241-247. PMID 30761250 DOI: 10.1002/2211-5463.12559 |
0.351 |
|
| 2019 |
Hinoi E, Iezaki T, Fukasawa K, Kaneda K. [Transcription Regulators and Bone Metabolism]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 139: 15-18. PMID 30606922 DOI: 10.1248/Yakushi.18-00154-1 |
0.51 |
|
| 2018 |
Ikegami R, Shimizu I, Sato T, Yoshida Y, Hayashi Y, Suda M, Katsuumi G, Li J, Wakasugi T, Minokoshi Y, Okamoto S, Hinoi E, Nielsen S, Jespersen NZ, Scheele C, et al. Gamma-Aminobutyric Acid Signaling in Brown Adipose Tissue Promotes Systemic Metabolic Derangement in Obesity. Cell Reports. 24: 2827-2837.e5. PMID 30208310 DOI: 10.1016/J.Celrep.2018.08.024 |
0.314 |
|
| 2018 |
Iezaki T, Horie T, Fukasawa K, Kitabatake M, Nakamura Y, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Manabe T, Ishigaki Y, Ohno M, ... Hinoi E, et al. Translational Control of Sox9 RNA by mTORC1 Contributes to Skeletogenesis. Stem Cell Reports. 11: 228-241. PMID 30008325 DOI: 10.1016/J.Stemcr.2018.05.020 |
0.407 |
|
| 2018 |
Iezaki T, Fukasawa K, Horie T, Park G, Robinson S, Nakaya M, Fujita H, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Yoneda Y, Takarada T, ... ... Hinoi E, et al. The MAPK Erk5 is necessary for proper skeletogenesis through a molecular axis that involves Smurfs-Smads-Sox9. Development (Cambridge, England). PMID 29986870 DOI: 10.1242/Dev.164004 |
0.344 |
|
| 2018 |
Ito Y, Fukui M, Kanda M, Morishita K, Shoji Y, Kitao T, Hinoi E, Shirahase H. Therapeutic effects of the allosteric protein tyrosine phosphatase 1B inhibitor KY-226 on experimental diabetes and obesity via enhancements in insulin and leptin signaling in mice. Journal of Pharmacological Sciences. PMID 29731242 DOI: 10.1016/J.Jphs.2018.03.001 |
0.366 |
|
| 2018 |
Korogi W, Yoshizawa T, Karim MF, Tanoue H, Yugami M, Sobuz SU, Hinoi E, Sato Y, Oike Y, Mizuta H, Yamagata K. SIRT7 is an important regulator of cartilage homeostasis and osteoarthritis development. Biochemical and Biophysical Research Communications. PMID 29402405 DOI: 10.1016/J.Bbrc.2018.01.129 |
0.391 |
|
| 2017 |
Horie T, Fukasawa K, Iezaki T, Park G, Onishi Y, Ozaki K, Kanayama T, Hiraiwa M, Kitaguchi Y, Kaneda K, Hinoi E. Hypoxic Stress Upregulates the Expression of Slc38a1 in Brown Adipocytes via Hypoxia-Inducible Factor-1α. Pharmacology. 101: 64-71. PMID 29065407 DOI: 10.1159/000480405 |
0.357 |
|
| 2017 |
Park G, Horie T, Kanayama T, Fukasawa K, Iezaki T, Onishi Y, Ozaki K, Nakamura Y, Yoneda Y, Takarada T, Hinoi E. The transcriptional modulator Ifrd1 controls PGC-1α expression under short-term adrenergic stimulation in brown adipocytes. The Febs Journal. PMID 28107769 DOI: 10.1111/Febs.14019 |
0.403 |
|
| 2017 |
Onishi Y, Park G, Iezaki T, Horie T, Kanayama T, Fukasawa K, Ozaki K, Hinoi E. The transcriptional modulator Ifrd1 is a negative regulator of BMP-2-dependent osteoblastogenesis. Biochemical and Biophysical Research Communications. 482: 329-334. PMID 27856249 DOI: 10.1016/J.Bbrc.2016.11.063 |
0.498 |
|
| 2016 |
Onishi Y, Fukasawa K, Ozaki K, Iezaki T, Yoneda Y, Hinoi E. GDF1 is a novel mediator of macrophage infiltration in brown adipose tissue of obese mice. Biochemistry and Biophysics Reports. 5: 216-223. PMID 28955827 DOI: 10.1016/J.Bbrep.2015.12.008 |
0.416 |
|
| 2016 |
Takarada T, Nakamichi N, Nakazato R, Kakuda T, Kokubo H, Ikeno S, Nakamura S, Kuramoto N, Hinoi E, Yoneda Y. Possible activation by the green tea amino acid theanine of mammalian target of rapamycin signaling in undifferentiated neural progenitor cells in vitro. Biochemistry and Biophysics Reports. 5: 89-95. PMID 28955810 DOI: 10.1016/J.Bbrep.2015.09.021 |
0.362 |
|
| 2016 |
Takarada T, Xu C, Ochi H, Nakazato R, Yamada D, Nakamura S, Kodama A, Shimba S, Mieda M, Fukasawa K, Ozaki K, Iezaki T, Fujikawa K, Yoneda Y, Numano R, ... ... Hinoi E, et al. Bone Resorption Is Regulated by Circadian Clock in Osteoblasts. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 27925286 DOI: 10.1002/Jbmr.3053 |
0.687 |
|
| 2016 |
Nakazato R, Hotta S, Yamada D, Kou M, Nakamura S, Takahata Y, Tei H, Numano R, Hida A, Shimba S, Mieda M, Hinoi E, Yoneda Y, Takarada T. The intrinsic microglial clock system regulates interleukin-6 expression. Glia. PMID 27726182 DOI: 10.1002/Glia.23087 |
0.372 |
|
| 2016 |
Fukasawa K, Park G, Iezaki T, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Yoneda Y, Takarada T, Kitajima S, Vacher J, Hinoi E. ATF3 controls proliferation of osteoclast precursor and bone remodeling. Scientific Reports. 6: 30918. PMID 27480204 DOI: 10.1038/Srep30918 |
0.485 |
|
| 2016 |
Fukasawa K, Hinoi E. [Regulation of bone homeostasis by glucose]. Clinical Calcium. 26: 1165-70. PMID 27461500 |
0.428 |
|
| 2016 |
Iezaki T, Fukasawa K, Park G, Horie T, Kanayama T, Ozaki K, Onishi Y, Takahata Y, Nakamura Y, Takarada T, Yoneda Y, Nakamura T, Vacher J, Hinoi E. The transcriptional modulator Ifrd1 regulates osteoclast differentiation through enhancing NF-κB/NFATc1 pathway. Molecular and Cellular Biology. PMID 27381458 DOI: 10.1128/Mcb.01075-15 |
0.477 |
|
| 2016 |
Iezaki T, Ozaki K, Fukasawa K, Inoue M, Kitajima S, Muneta T, Takeda S, Fujita H, Onishi Y, Horie T, Yoneda Y, Takarada T, Hinoi E. ATF3 deficiency in chondrocytes alleviates osteoarthritis development. The Journal of Pathology. PMID 27159257 DOI: 10.1002/Path.4739 |
0.623 |
|
| 2016 |
Takarada T, Kou M, Hida M, Fukumori R, Nakamura S, Kutsukake T, Kuramoto N, Hinoi E, Yoneda Y. Protective upregulation of activating transcription factor-3 against glutamate neurotoxicity in neuronal cells under ischemia. Journal of Neuroscience Research. PMID 26900013 DOI: 10.1002/Jnr.23723 |
0.38 |
|
| 2016 |
Xu C, Ochi H, Fukuda T, Sato S, Sunamura S, Takarada T, Hinoi E, Okawa A, Takeda S. Circadian Clock Regulates Bone Resorption in Mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26841172 DOI: 10.1002/Jbmr.2803 |
0.671 |
|
| 2015 |
Takarada T, Nakazato R, Tsuchikane A, Fujikawa K, Iezaki T, Yoneda Y, Hinoi E. Genetic analysis of Runx2 function during intramembranous ossification. Development (Cambridge, England). PMID 26657773 DOI: 10.1242/Dev.128793 |
0.495 |
|
| 2015 |
Iezaki T, Onishi Y, Ozaki K, Fukasawa K, Takahata Y, Nakamura Y, Fujikawa K, Takarada T, Yoneda Y, Yamashita Y, Shioi G, Hinoi E. The Transcriptional Modulator Interferon-Related Developmental Regulator 1 in Osteoblasts Suppresses Bone Formation and Promotes Bone Resorption. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. PMID 26391411 DOI: 10.1002/Jbmr.2720 |
0.485 |
|
| 2015 |
Ozaki K, Okamoto M, Fukasawa K, Iezaki T, Onishi Y, Yoneda Y, Sugiura M, Hinoi E. Daily intake of β-cryptoxanthin prevents bone loss by preferential disturbance of osteoclastic activation in ovariectomized mice. Journal of Pharmacological Sciences. 129: 72-7. PMID 26342276 DOI: 10.1016/J.Jphs.2015.08.003 |
0.433 |
|
| 2015 |
Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Lezaki T, Pessin JE, Hinoi E, Karsenty G. Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation. Cell. 161: 1576-91. PMID 26091038 DOI: 10.1016/J.Cell.2015.05.029 |
0.769 |
|
| 2015 |
Takarada T, Ogura M, Nakamichi N, Kakuda T, Nakazato R, Kokubo H, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y. Upregulation of Slc38a1 Gene Along with Promotion of Neurosphere Growth and Subsequent Neuronal Specification in Undifferentiated Neural Progenitor Cells Exposed to Theanine. Neurochemical Research. PMID 25957749 DOI: 10.1007/S11064-015-1591-4 |
0.36 |
|
| 2015 |
Nakazato R, Takarada T, Ikeno S, Nakamura S, Kutsukake T, Hinoi E, Yoneda Y. Upregulation of Runt-Related Transcription Factor-2 Through CCAAT Enhancer Binding Protein-β Signaling Pathway in Microglial BV-2 Cells Exposed to ATP. Journal of Cellular Physiology. 230: 2510-21. PMID 25802132 DOI: 10.1002/Jcp.24988 |
0.401 |
|
| 2015 |
Wei J, Shimazu J, Makinistoglu MP, Maurizi A, Kajimura D, Zong H, Takarada T, Iezaki T, Pessin JE, Hinoi E, Karsenty G. Erratum:Glucose Uptake and Runx2 Synergize to Orchestrate Osteoblast Differentiation and Bone Formation (Cell (2015) 161 (1576-1591)) Cell. 162. DOI: 10.1016/J.Cell.2015.08.018 |
0.616 |
|
| 2014 |
Hinoi E. [Regulation of osteoclastogenesis by osteocytes through growth differentiation factor-15]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 134: 1259-63. PMID 25452236 DOI: 10.1248/Yakushi.14-00209-4 |
0.477 |
|
| 2014 |
Hinoi E, Iezaki T, Ozaki K, Yoneda Y. Nuclear factor-κB is a common upstream signal for growth differentiation factor-5 expression in brown adipocytes exposed to pro-inflammatory cytokines and palmitate. Biochemical and Biophysical Research Communications. 452: 974-9. PMID 25223801 DOI: 10.1016/J.Bbrc.2014.09.022 |
0.39 |
|
| 2014 |
Hinoi E, Iezaki T, Fujita H, Watanabe T, Odaka Y, Ozaki K, Yoneda Y. PI3K/Akt is involved in brown adipogenesis mediated by growth differentiation factor-5 in association with activation of the Smad pathway. Biochemical and Biophysical Research Communications. 450: 255-60. PMID 24944017 DOI: 10.1016/J.Bbrc.2014.05.108 |
0.422 |
|
| 2014 |
Nakazato R, Takarada T, Watanabe T, Nguyen BT, Ikeno S, Hinoi E, Yoneda Y. Constitutive and functional expression of runt-related transcription factor-2 by microglial cells. Neurochemistry International. 74: 24-35. PMID 24768841 DOI: 10.1016/J.Neuint.2014.04.010 |
0.412 |
|
| 2014 |
Kubo M, Fukui M, Ito Y, Kitao T, Shirahase H, Hinoi E, Yoneda Y. Insulin sensitization by a novel partial peroxisome proliferator-activated receptor γ agonist with protein tyrosine phosphatase 1B inhibitory activity in experimental osteoporotic rats. Journal of Pharmacological Sciences. 124: 276-85. PMID 24553405 DOI: 10.1254/Jphs.13236Fp |
0.42 |
|
| 2014 |
Hinoi E, Nakamura Y, Takada S, Fujita H, Iezaki T, Hashizume S, Takahashi S, Odaka Y, Watanabe T, Yoneda Y. Growth differentiation factor-5 promotes brown adipogenesis in systemic energy expenditure. Diabetes. 63: 162-75. PMID 24062245 DOI: 10.2337/Db13-0808 |
0.409 |
|
| 2013 |
Le NQ, Binh NT, Takarada T, Takarada-Iemata M, Hinoi E, Yoneda Y. Negative correlation between Per1 and Sox6 expression during chondrogenic differentiation in pre-chondrocytic ATDC5 cells. Journal of Pharmacological Sciences. 122: 318-25. PMID 23883486 DOI: 10.1254/Jphs.13091Fp |
0.426 |
|
| 2013 |
Takarada T, Kou M, Nakamichi N, Ogura M, Ito Y, Fukumori R, Kokubo H, Acosta GB, Hinoi E, Yoneda Y. Myosin VI reduces proliferation, but not differentiation, in pluripotent P19 cells. Plos One. 8: e63947. PMID 23691122 DOI: 10.1371/Journal.Pone.0063947 |
0.356 |
|
| 2013 |
Takarada T, Hinoi E, Nakazato R, Ochi H, Xu C, Tsuchikane A, Takeda S, Karsenty G, Abe T, Kiyonari H, Yoneda Y. An analysis of skeletal development in osteoblast-specific and chondrocyte-specific runt-related transcription factor-2 (Runx2) knockout mice. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 28: 2064-9. PMID 23553905 DOI: 10.1002/Jbmr.1945 |
0.689 |
|
| 2013 |
Nakamura Y, Hinoi E, Iezaki T, Takada S, Hashizume S, Takahata Y, Tsuruta E, Takahashi S, Yoneda Y. Repression of adipogenesis through promotion of Wnt/β-catenin signaling by TIS7 up-regulated in adipocytes under hypoxia. Biochimica Et Biophysica Acta. 1832: 1117-28. PMID 23517917 DOI: 10.1016/J.Bbadis.2013.03.010 |
0.389 |
|
| 2013 |
Fujita H, Hinoi E, Watanabe T, Iezaki T, Takamori M, Ogawa S, Yoneda Y. Prevention of bone loss after ovariectomy in mice with preferential overexpression of the transcription factor paired box-5 in osteoblasts. Biological & Pharmaceutical Bulletin. 36: 481-4. PMID 23449333 DOI: 10.1248/Bpb.B12-00893 |
0.474 |
|
| 2013 |
Kikuta M, Shiba T, Yoneyama M, Kawada K, Yamaguchi T, Hinoi E, Yoneda Y, Ogita K. In vivo and in vitro treatment with edaravone promotes proliferation of neural progenitor cells generated following neuronal loss in the mouse dentate gyrus. Journal of Pharmacological Sciences. 121: 74-83. PMID 23269236 DOI: 10.1254/Jphs.12162Fp |
0.329 |
|
| 2012 |
Ogura M, Kakuda T, Takarada T, Nakamichi N, Fukumori R, Kim YH, Hinoi E, Yoneda Y. Promotion of both proliferation and neuronal differentiation in pluripotent P19 cells with stable overexpression of the glutamine transporter slc38a1. Plos One. 7: e48270. PMID 23110224 DOI: 10.1371/Journal.Pone.0048270 |
0.374 |
|
| 2012 |
Takarada T, Kodama A, Hotta S, Mieda M, Shimba S, Hinoi E, Yoneda Y. Clock genes influence gene expression in growth plate and endochondral ossification in mice. The Journal of Biological Chemistry. 287: 36081-95. PMID 22936800 DOI: 10.1074/Jbc.M112.408963 |
0.432 |
|
| 2012 |
Takahata Y, Hinoi E, Takarada T, Nakamura Y, Ogawa S, Yoneda Y. Positive regulation by γ-aminobutyric acid B receptor subunit-1 of chondrogenesis through acceleration of nuclear translocation of activating transcription factor-4. The Journal of Biological Chemistry. 287: 33293-303. PMID 22879594 DOI: 10.1074/Jbc.M112.344051 |
0.351 |
|
| 2012 |
Hinoi E, Nakatani E, Yamamoto T, Iezaki T, Takahata Y, Fujita H, Ishiura R, Takamori M, Yoneda Y. The transcription factor paired box-5 promotes osteoblastogenesis through direct induction of Osterix and Osteocalcin. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 2526-34. PMID 22807088 DOI: 10.1002/Jbmr.1708 |
0.517 |
|
| 2012 |
Hinoi E. [Elucidation of signal response mechanisms in bone-related cell lineages]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 140: 3-7. PMID 22790225 DOI: 10.1254/Fpj.140.3 |
0.404 |
|
| 2012 |
Hinoi E. [Pivotal role of skeletal tissues in the regulation mechanisms for physiological functions mediated by multiple organ networks]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 132: 721-5. PMID 22687731 DOI: 10.1248/Yakushi.132.721 |
0.529 |
|
| 2012 |
Fujita H, Hinoi E, Nakatani E, Yamamoto T, Takarada T, Yoneda Y. Possible modulation of process extension by N-methyl-D-aspartate receptor expressed in osteocytic MLO-Y4 cells. Journal of Pharmacological Sciences. 119: 112-6. PMID 22641131 DOI: 10.1254/Jphs.12068Sc |
0.408 |
|
| 2012 |
Iezaki T, Hinoi E, Yamamoto T, Ishiura R, Ogawa S, Yoneda Y. Amelioration by the natural polyamine spermine of cartilage and bone destruction in rats with collagen-induced arthritis. Journal of Pharmacological Sciences. 119: 107-11. PMID 22641127 DOI: 10.1254/Jphs.11241Sc |
0.375 |
|
| 2012 |
Takarada T, Takarada-Iemata M, Takahata Y, Yamada D, Yamamoto T, Nakamura Y, Hinoi E, Yoneda Y. Osteoclastogenesis is negatively regulated by D-serine produced by osteoblasts. Journal of Cellular Physiology. 227: 3477-87. PMID 22252936 DOI: 10.1002/Jcp.24048 |
0.454 |
|
| 2012 |
Yamamoto T, Hinoi E, Fujita H, Iezaki T, Takahata Y, Takamori M, Yoneda Y. The natural polyamines spermidine and spermine prevent bone loss through preferential disruption of osteoclastic activation in ovariectomized mice. British Journal of Pharmacology. 166: 1084-96. PMID 22250848 DOI: 10.1111/J.1476-5381.2012.01856.X |
0.48 |
|
| 2012 |
Hinoi E, Ochi H, Takarada T, Nakatani E, Iezaki T, Nakajima H, Fujita H, Takahata Y, Hidano S, Kobayashi T, Takeda S, Yoneda Y. Positive regulation of osteoclastic differentiation by growth differentiation factor 15 upregulated in osteocytic cells under hypoxia. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 27: 938-49. PMID 22190281 DOI: 10.1002/Jbmr.1538 |
0.689 |
|
| 2011 |
Takahata Y, Takarada T, Hinoi E, Nakamura Y, Fujita H, Yoneda Y. Osteoblastic γ-aminobutyric acid, type B receptors negatively regulate osteoblastogenesis toward disturbance of osteoclastogenesis mediated by receptor activator of nuclear factor κB ligand in mouse bone. The Journal of Biological Chemistry. 286: 32906-17. PMID 21828041 DOI: 10.1074/Jbc.M111.253526 |
0.402 |
|
| 2011 |
Nakazato R, Takarada T, Yamamoto T, Hotta S, Hinoi E, Yoneda Y. Selective upregulation of Per1 mRNA expression by ATP through activation of P2X7 purinergic receptors expressed in microglial cells. Journal of Pharmacological Sciences. 116: 350-61. PMID 21747211 DOI: 10.1254/Jphs.11069Fp |
0.377 |
|
| 2011 |
Hinoi E, Yoneda Y. Possible involvement of glutamatergic signaling machineries in pathophysiology of rheumatoid arthritis. Journal of Pharmacological Sciences. 116: 248-56. PMID 21666346 DOI: 10.1254/Jphs.11R03Cr |
0.334 |
|
| 2011 |
Nakamura Y, Hinoi E, Takarada T, Takahata Y, Yamamoto T, Fujita H, Takada S, Hashizume S, Yoneda Y. Positive regulation by GABA(B)R1 subunit of leptin expression through gene transactivation in adipocytes. Plos One. 6: e20167. PMID 21655283 DOI: 10.1371/Journal.Pone.0020167 |
0.32 |
|
| 2011 |
Kajimura D, Hinoi E, Ferron M, Kode A, Riley KJ, Zhou B, Guo XE, Karsenty G. Genetic determination of the cellular basis of the sympathetic regulation of bone mass accrual. The Journal of Experimental Medicine. 208: 841-51. PMID 21444660 DOI: 10.1084/Jem.20102608 |
0.753 |
|
| 2011 |
Uno K, Takarada T, Nakamura Y, Fujita H, Hinoi E, Yoneda Y. A negative correlation between expression profiles of runt-related transcription factor-2 and cystine/glutamate antiporter xCT subunit in ovariectomized mouse bone. Journal of Pharmacological Sciences. 115: 309-19. PMID 21325781 DOI: 10.1254/Jphs.10310Fp |
0.493 |
|
| 2011 |
Uno K, Takarada T, Takarada-Iemata M, Nakamura Y, Fujita H, Hinoi E, Yoneda Y. Negative regulation of osteoblastogenesis through downregulation of runt-related transcription factor-2 in osteoblastic MC3T3-E1 cells with stable overexpression of the cystine/glutamate antiporter xCT subunit. Journal of Cellular Physiology. 226: 2953-64. PMID 21302293 DOI: 10.1002/Jcp.22642 |
0.462 |
|
| 2010 |
Hinoi E. [Control of bone remodeling by nervous system. Regulation of glucose metabolism by skeleton. - Tangent point with nervous system -]. Clinical Calcium. 20: 1814-9. PMID 21123933 |
0.382 |
|
| 2010 |
Hinoi E. [Functional glutamate signaling in bone]. Yakugaku Zasshi : Journal of the Pharmaceutical Society of Japan. 130: 1175-9. PMID 20823674 DOI: 10.1248/Yakushi.130.1175 |
0.484 |
|
| 2009 |
Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Kajimura D, Myers MG, Chua SC, Wang Q, Kim JK, Kaestner KH, Karsenty G. An Osteoblast-dependent mechanism contributes to the leptin regulation of insulin secretion. Annals of the New York Academy of Sciences. 1173: E20-30. PMID 19751411 DOI: 10.1111/J.1749-6632.2009.05061.X |
0.744 |
|
| 2009 |
Yoshizawa T, Hinoi E, Jung DY, Kajimura D, Ferron M, Seo J, Graff JM, Kim JK, Karsenty G. The transcription factor ATF4 regulates glucose metabolism in mice through its expression in osteoblasts. The Journal of Clinical Investigation. 119: 2807-17. PMID 19726872 DOI: 10.1172/Jci39366 |
0.755 |
|
| 2009 |
Takarada T, Takahata Y, Iemata M, Hinoi E, Uno K, Hirai T, Yamamoto T, Yoneda Y. Interference with cellular differentiation by D-serine through antagonism at N-methyl-D-aspartate receptors composed of NR1 and NR3A subunits in chondrocytes. Journal of Cellular Physiology. 220: 756-64. PMID 19452450 DOI: 10.1002/Jcp.21821 |
0.355 |
|
| 2009 |
Takarada T, Hojo H, Iemata M, Sahara K, Kodama A, Nakamura N, Hinoi E, Yoneda Y. Interference by adrenaline with chondrogenic differentiation through suppression of gene transactivation mediated by Sox9 family members. Bone. 45: 568-78. PMID 19446054 DOI: 10.1016/J.Bone.2009.05.004 |
0.429 |
|
| 2009 |
Nakamura Y, Takarada T, Kodama A, Hinoi E, Yoneda Y. Predominant promotion by tacrolimus of chondrogenic differentiation to proliferating chondrocytes. Journal of Pharmacological Sciences. 109: 413-23. PMID 19270431 DOI: 10.1254/Jphs.08315Fp |
0.409 |
|
| 2008 |
Hinoi E, Gao N, Jung DY, Yadav V, Yoshizawa T, Myers MG, Chua SC, Kim JK, Kaestner KH, Karsenty G. The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity. The Journal of Cell Biology. 183: 1235-42. PMID 19103808 DOI: 10.1083/Jcb.200809113 |
0.705 |
|
| 2008 |
Takahata Y, Takarada T, Osawa M, Hinoi E, Nakamura Y, Yoneda Y. Differential regulation of cellular maturation in chondrocytes and osteoblasts by glycine. Cell and Tissue Research. 333: 91-103. PMID 18427837 DOI: 10.1007/S00441-008-0607-7 |
0.384 |
|
| 2008 |
Ferron M, Hinoi E, Karsenty G, Ducy P. Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 5266-70. PMID 18362359 DOI: 10.1073/Pnas.0711119105 |
0.78 |
|
| 2008 |
Takarada T, Hinoi E, Takahata Y, Yoneda Y. Serine racemase suppresses chondrogenic differentiation in cartilage in a Sox9-dependent manner. Journal of Cellular Physiology. 215: 320-8. PMID 17929246 DOI: 10.1002/Jcp.21310 |
0.412 |
|
| 2007 |
Takarada T, Hinoi E, Kambe Y, Sahara K, Kurokawa S, Takahata Y, Yoneda Y. Osteoblast protects osteoclast devoid of sodium-dependent vitamin C transporters from oxidative cytotoxicity of ascorbic acid. European Journal of Pharmacology. 575: 1-11. PMID 17698058 DOI: 10.1016/J.Ejphar.2007.07.041 |
0.398 |
|
| 2007 |
Lee NK, Sowa H, Hinoi E, Ferron M, Ahn JD, Confavreux C, Dacquin R, Mee PJ, McKee MD, Jung DY, Zhang Z, Kim JK, Mauvais-Jarvis F, Ducy P, Karsenty G. Endocrine regulation of energy metabolism by the skeleton. Cell. 130: 456-69. PMID 17693256 DOI: 10.1016/J.Cell.2007.05.047 |
0.787 |
|
| 2007 |
Iemata M, Takarada T, Hinoi E, Taniura H, Yoneda Y. Suppression by glutamate of proliferative activity through glutathione depletion mediated by the cystine/glutamate antiporter in mesenchymal C3H10T1/2 stem cells. Journal of Cellular Physiology. 213: 721-9. PMID 17520696 DOI: 10.1002/Jcp.21145 |
0.407 |
|
| 2007 |
Uno K, Takarada T, Hinoi E, Yoneda Y. Glutamate is a determinant of cellular proliferation through modulation of nuclear factor E2 p45-related factor-2 expression in osteoblastic MC3T3-E1 cells. Journal of Cellular Physiology. 213: 105-14. PMID 17443688 DOI: 10.1002/Jcp.21095 |
0.414 |
|
| 2007 |
Hinoi E, Takarada T, Uno K, Inoue M, Murafuji Y, Yoneda Y. Glutamate suppresses osteoclastogenesis through the cystine/glutamate antiporter. The American Journal of Pathology. 170: 1277-90. PMID 17392167 DOI: 10.2353/Ajpath.2007.061039 |
0.419 |
|
| 2007 |
Moriguchi N, Hinoi E, Takarada T, Matsushima N, Uno K, Yoneda Y. Oral administration of phenolic antidiarrheic ingredients prevents ovariectomy-induced bone loss. Biochemical Pharmacology. 73: 385-93. PMID 17078932 DOI: 10.1016/J.Bcp.2006.09.025 |
0.461 |
|
| 2007 |
Hinoi E, Takarada T, Fujimori S, Wang L, Iemata M, Uno K, Yoneda Y. Nuclear factor E2 p45-related factor 2 negatively regulates chondrogenesis. Bone. 40: 337-44. PMID 17029980 DOI: 10.1016/J.Bone.2006.08.016 |
0.455 |
|
| 2006 |
Hinoi E, Bialek P, Chen YT, Rached MT, Groner Y, Behringer RR, Ornitz DM, Karsenty G. Runx2 inhibits chondrocyte proliferation and hypertrophy through its expression in the perichondrium. Genes & Development. 20: 2937-42. PMID 17050674 DOI: 10.1101/Gad.1482906 |
0.771 |
|
| 2006 |
Fujimori S, Hinoi E, Takarada T, Iemata M, Takahata Y, Yoneda Y. Possible expression of a particular gamma-aminobutyric acid transporter isoform responsive to upregulation by hyperosmolarity in rat calvarial osteoblasts. European Journal of Pharmacology. 550: 24-32. PMID 17022965 DOI: 10.1016/J.Ejphar.2006.08.088 |
0.354 |
|
| 2006 |
Wang L, Hinoi E, Takemori A, Nakamichi N, Yoneda Y. Glutamate inhibits chondral mineralization through apoptotic cell death mediated by retrograde operation of the cystine/glutamate antiporter. The Journal of Biological Chemistry. 281: 24553-65. PMID 16790444 DOI: 10.1074/Jbc.M600939200 |
0.399 |
|
| 2006 |
Hinoi E, Ueshima T, Hojo H, Iemata M, Takarada T, Yoneda Y. Up-regulation of per mRNA expression by parathyroid hormone through a protein kinase A-CREB-dependent mechanism in chondrocytes. The Journal of Biological Chemistry. 281: 23632-42. PMID 16777848 DOI: 10.1074/Jbc.M512362200 |
0.458 |
|
| 2006 |
Hinoi E, Takarada T, Tsuchihashi Y, Fujimori S, Moriguchi N, Wang L, Uno K, Yoneda Y. A molecular mechanism of pyruvate protection against cytotoxicity of reactive oxygen species in osteoblasts. Molecular Pharmacology. 70: 925-35. PMID 16766717 DOI: 10.1124/Mol.106.024398 |
0.46 |
|
| 2006 |
Moriguchi N, Hinoi E, Tsuchihashi Y, Fujimori S, Iemata M, Takarada T, Yoneda Y. Cytoprotection by pyruvate through an anti-oxidative mechanism in cultured rat calvarial osteoblasts. Histology and Histopathology. 21: 969-77. PMID 16763947 DOI: 10.14670/Hh-21.969 |
0.337 |
|
| 2006 |
Hinoi E, Fujimori S, Wang L, Hojo H, Uno K, Yoneda Y. Nrf2 negatively regulates osteoblast differentiation via interfering with Runx2-dependent transcriptional activation. The Journal of Biological Chemistry. 281: 18015-24. PMID 16613847 DOI: 10.1074/Jbc.M600603200 |
0.484 |
|
| 2006 |
Fujimori S, Osawa M, Iemata M, Hinoi E, Yoneda Y. Increased GABA transport activity in rat calvarial osteoblasts cultured under hyperglycemic conditions. Biological & Pharmaceutical Bulletin. 29: 297-301. PMID 16462035 DOI: 10.1248/Bpb.29.297 |
0.398 |
|
| 2005 |
Hinoi E, Ohashi R, Miyata S, Kato Y, Iemata M, Hojo H, Takarada T, Yoneda Y. Excitatory amino acid transporters expressed by synovial fibroblasts in rats with collagen-induced arthritis. Biochemical Pharmacology. 70: 1744-55. PMID 16242118 DOI: 10.1016/J.Bcp.2005.09.010 |
0.349 |
|
| 2005 |
Wang L, Hinoi E, Takemori A, Takarada T, Yoneda Y. Abolition of chondral mineralization by group III metabotropic glutamate receptors expressed in rodent cartilage. British Journal of Pharmacology. 146: 732-43. PMID 16086032 DOI: 10.1038/Sj.Bjp.0706358 |
0.409 |
|
| 2005 |
Wang L, Hinoi E, Takemori A, Yoneda Y. Release of endogenous glutamate by AMPA receptors expressed in cultured rat costal chondrocytes. Biological & Pharmaceutical Bulletin. 28: 990-3. PMID 15930732 DOI: 10.1248/Bpb.28.990 |
0.37 |
|
| 2005 |
Hinoi E, Wang L, Takemori A, Yoneda Y. Functional expression of particular isoforms of excitatory amino acid transporters by rodent cartilage. Biochemical Pharmacology. 70: 70-81. PMID 15894296 DOI: 10.1016/J.Bcp.2005.04.025 |
0.379 |
|
| 2005 |
Nakamichi N, Kambe Y, Oikawa H, Ogura M, Takano K, Tamaki K, Inoue M, Hinoi E, Yoneda Y. Protection by exogenous pyruvate through a mechanism related to monocarboxylate transporters against cell death induced by hydrogen peroxide in cultured rat cortical neurons. Journal of Neurochemistry. 93: 84-93. PMID 15773908 DOI: 10.1111/J.1471-4159.2005.02999.X |
0.307 |
|
| 2005 |
Hinoi E, Takarada T, Yoneda Y. Glutamate signaling system in bone. Journal of Pharmacological Sciences. 94: 215-20. PMID 15037805 DOI: 10.1254/Jphs.94.215 |
0.382 |
|
| 2005 |
Hinoi E, Wang L, Fujimori S, Yoneda Y. nrf2 Expressed by Bone Journal of Hard Tissue Biology. 14: 280-281. DOI: 10.2485/Jhtb.14.280 |
0.512 |
|
| 2004 |
Takarada T, Hinoi E, Fujimori S, Tsuchihashi Y, Ueshima T, Taniura H, Yoneda Y. Accumulation of [3H] glutamate in cultured rat calvarial osteoblasts. Biochemical Pharmacology. 68: 177-84. PMID 15183129 DOI: 10.1016/J.Bcp.2004.03.020 |
0.387 |
|
| 2004 |
Takarada T, Hinoi E, Balcar VJ, Taniura H, Yoneda Y. Possible expression of functional glutamate transporters in the rat testis. The Journal of Endocrinology. 181: 233-44. PMID 15128272 DOI: 10.1677/Joe.0.1810233 |
0.329 |
|
| 2004 |
Yoneda Y, Hinoi E. [Functional expression of machineries for glutamate signaling in bone]. Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. 14P-17P. PMID 14727510 |
0.305 |
|
| 2004 |
Hinoi E, Takarada T, Ueshima T, Tsuchihashi Y, Yoneda Y. Glutamate signaling in peripheral tissues. European Journal of Biochemistry. 271: 1-13. PMID 14686914 DOI: 10.1046/J.1432-1033.2003.03907.X |
0.328 |
|
| 2003 |
Hinoi E, Fujimori S, Yoneda Y. Modulation of cellular differentiation by N-methyl-D-aspartate receptors in osteoblasts. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 1532-4. PMID 12824297 DOI: 10.1096/Fj.02-0820Fje |
0.377 |
|
| 2003 |
Hinoi E, Balcar VJ, Kuramoto N, Nakamichi N, Yoneda Y. Nuclear transcription factors in the hippocampus. Progress in Neurobiology. 68: 145-65. PMID 12450491 DOI: 10.1016/S0301-0082(02)00078-3 |
0.332 |
|
| 2002 |
Hinoi E, Fujimori S, Takarada T, Taniura H, Yoneda Y. Facilitation of glutamate release by ionotropic glutamate receptors in osteoblasts. Biochemical and Biophysical Research Communications. 297: 452-8. PMID 12270113 DOI: 10.1016/S0006-291X(02)02223-4 |
0.313 |
|
| 2002 |
Hinoi E, Fujimori S, Takemori A, Kurabayashi H, Nakamura Y, Yoneda Y. Demonstration of expression of mRNA for particular AMPA and kainate receptor subunits in immature and mature cultured rat calvarial osteoblasts. Brain Research. 943: 112-6. PMID 12088845 DOI: 10.1016/S0006-8993(02)02726-9 |
0.356 |
|
| 2002 |
Hinoi E, Fujimori S, Takemori A, Yoneda Y. Cell death by pyruvate deficiency in proliferative cultured calvarial osteoblasts. Biochemical and Biophysical Research Communications. 294: 1177-83. PMID 12074601 DOI: 10.1016/S0006-291X(02)00578-8 |
0.33 |
|
| 2002 |
Fujimori S, Hinoi E, Yoneda Y. Functional GABA(B) receptors expressed in cultured calvarial osteoblasts. Biochemical and Biophysical Research Communications. 293: 1445-52. PMID 12054677 DOI: 10.1016/S0006-291X(02)00405-9 |
0.307 |
|
| 2001 |
Hinoi E, Fujimori S, Nakamura Y, Yoneda Y. Group III metabotropic glutamate receptors in rat cultured calvarial osteoblasts. Biochemical and Biophysical Research Communications. 281: 341-6. PMID 11181052 DOI: 10.1006/Bbrc.2001.4355 |
0.369 |
|
| 2001 |
Yoneda Y, Kuramoto N, Kitayama T, Hinoi E. Consolidation of transient ionotropic glutamate signals through nuclear transcription factors in the brain. Progress in Neurobiology. 63: 697-719. PMID 11165002 DOI: 10.1016/S0301-0082(00)00036-8 |
0.357 |
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