Richard D. Kolodner - Publications

Affiliations: 
1978-1997 Biological Chemistry and Molecular Pharmacology Harvard Medical School, Boston, MA, United States 
 1997- Cellular and Molecular Medicine University of California, San Diego, La Jolla, CA 
Area:
genetic recombination and DNA repair
Website:
http://igm.ucsd.edu/faculty/profiles/kolodner.shtml

220 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Srivatsan A, Li B, Sanchez DN, Somach SB, da Silva VL, de Souza SJ, Putnam CD, Kolodner RD. Essential genome instability suppressing genes identify potential human tumor suppressors. Proceedings of the National Academy of Sciences of the United States of America. PMID 31409704 DOI: 10.1073/pnas.1906921116  1
2019 Hoss F, Mueller JL, Rojas Ringeling F, Rodriguez-Alcazar JF, Brinkschulte R, Seifert G, Stahl R, Broderick L, Putnam CD, Kolodner RD, Canzar S, Geyer M, Hoffman HM, Latz E. Alternative splicing regulates stochastic NLRP3 activity. Nature Communications. 10: 3238. PMID 31324763 DOI: 10.1038/s41467-019-11076-1  1
2019 Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, ... ... Kolodner RD, et al. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. 35: 816. PMID 31085179 DOI: 10.1016/j.ccell.2019.04.011  0.72
2019 Ma J, Benitez JA, Li J, Miki S, Ponte de Albuquerque C, Galatro T, Orellana L, Zanca C, Reed R, Boyer A, Koga T, Varki NM, Fenton TR, Nagahashi Marie SK, Lindahl E, ... ... Kolodner RD, et al. Inhibition of Nuclear PTEN Tyrosine Phosphorylation Enhances Glioma Radiation Sensitivity through Attenuated DNA Repair. Cancer Cell. PMID 30827889 DOI: 10.1016/j.ccell.2019.01.020  0.72
2019 Klein HL, Bačinskaja G, Che J, Cheblal A, Elango R, Epshtein A, Fitzgerald DM, Gómez-González B, Khan SR, Kumar S, Leland BA, Marie L, Mei Q, Miné-Hattab J, Piotrowska A, ... ... Kolodner RD, et al. Guidelines for DNA recombination and repair studies: Cellular assays of DNA repair pathways. Microbial Cell (Graz, Austria). 6: 1-64. PMID 30652105 DOI: 10.15698/mic2019.01.664  1
2018 Graham WJ, Putnam CD, Kolodner RD. The properties of Msh2-Msh6 ATP binding mutants suggest a signal amplification mechanism in DNA mismatch repair. The Journal of Biological Chemistry. PMID 30237169 DOI: 10.1074/jbc.RA118.005439  1
2018 Srivatsan A, Li BZ, Szakal B, Branzei D, Putnam CD, Kolodner RD. The Swr1 chromatin-remodeling complex prevents genome instability induced by replication fork progression defects. Nature Communications. 9: 3680. PMID 30206225 DOI: 10.1038/s41467-018-06131-2  1
2018 Goellner EM, Putnam CD, Graham WJ, Rahal CM, Li BZ, Kolodner RD. Identification of Exo1-Msh2 interaction motifs in DNA mismatch repair and new Msh2-binding partners. Nature Structural & Molecular Biology. PMID 30061603 DOI: 10.1038/s41594-018-0092-y  1
2018 Liang J, Li BZ, Tan AP, Kolodner RD, Putnam CD, Zhou H. SUMO E3 ligase Mms21 prevents spontaneous DNA damage induced genome rearrangements. Plos Genetics. 14: e1007250. PMID 29505562 DOI: 10.1371/journal.pgen.1007250  1
2018 Nene RV, Putnam CD, Li BZ, Nguyen KG, Srivatsan A, Campbell CS, Desai A, Kolodner RD. Cdc73 suppresses genome instability by mediating telomere homeostasis. Plos Genetics. 14: e1007170. PMID 29320491 DOI: 10.1371/journal.pgen.1007170  1
2018 Srivatsan A, Putnam CD, Kolodner RD. Analyzing Genome Rearrangements in Saccharomyces cerevisiae. Methods in Molecular Biology (Clifton, N.J.). 1672: 43-61. PMID 29043616 DOI: 10.1007/978-1-4939-7306-4_5  1
2017 Putnam CD, Kolodner RD. Pathways and Mechanisms that Prevent Genome Instability in Saccharomyces cerevisiae. Genetics. 206: 1187-1225. PMID 28684602 DOI: 10.1534/genetics.112.145805  1
2017 Bowen N, Kolodner RD. Reconstitution of Saccharomyces cerevisiae DNA polymerase ε-dependent mismatch repair with purified proteins. Proceedings of the National Academy of Sciences of the United States of America. PMID 28265089 DOI: 10.1073/pnas.1701753114  0.56
2016 Breuss MW, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, Hansen AH, Musaev D, McEvoy-Venneri J, James KN, Rosti RO, Scott E, Tan U, Kolodner RD, Cowan NJ, et al. Uner Tan Syndrome Caused by a Homozygous TUBB2B Mutation Affecting Microtubule Stability. Human Molecular Genetics. PMID 28013290 DOI: 10.1093/hmg/ddw383  1
2016 Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. Correction: Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements. Plos Genetics. 12: e1006302. PMID 27579875 DOI: 10.1371/journal.pgen.1006302  1
2016 Putnam CD, Srivatsan A, Nene RV, Martinez SL, Clotfelter SP, Bell SN, Somach SB, E S de Souza J, Fonseca AF, de Souza SJ, Kolodner RD. A genetic network that suppresses genome rearrangements in Saccharomyces cerevisiae and contains defects in cancers. Nature Communications. 7: 11256. PMID 27071721 DOI: 10.1038/ncomms11256  1
2015 Kolodner RD. A personal historical view of DNA mismatch repair with an emphasis on eukaryotic DNA mismatch repair. Dna Repair. PMID 26698650 DOI: 10.1016/j.dnarep.2015.11.009  1
2015 Goellner EM, Putnam CD, Kolodner RD. Exonuclease 1-dependent and independent mismatch repair. Dna Repair. 32: 24-32. PMID 25956862 DOI: 10.1016/j.dnarep.2015.04.010  1
2015 Reyes GX, Schmidt TT, Kolodner RD, Hombauer H. New insights into the mechanism of DNA mismatch repair. Chromosoma. PMID 25862369 DOI: 10.1007/s00412-015-0514-0  1
2015 Goellner EM, Putnam CD, Kolodner RD. Exonuclease 1-dependent and independent mismatch repair Dna Repair. 32: 24-32. DOI: 10.1016/j.dnarep.2015.04.010  1
2014 Ragu S, Dardalhon M, Sharma S, Iraqui I, Buhagiar-Labarchède G, Grondin V, Kienda G, Vernis L, Chanet R, Kolodner RD, Huang ME, Faye G. Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin tsa1 mutants. Plos One. 9: e108123. PMID 25247923 DOI: 10.1371/journal.pone.0108123  0.92
2014 Goellner EM, Smith CE, Campbell CS, Hombauer H, Desai A, Putnam CD, Kolodner RD. PCNA and Msh2-Msh6 activate an Mlh1-Pms1 endonuclease pathway required for Exo1-independent mismatch repair. Molecular Cell. 55: 291-304. PMID 24981171 DOI: 10.1016/j.molcel.2014.04.034  1
2014 Campbell CS, Hombauer H, Srivatsan A, Bowen N, Gries K, Desai A, Putnam CD, Kolodner RD. Mlh2 is an accessory factor for DNA mismatch repair in Saccharomyces cerevisiae. Plos Genetics. 10: e1004327. PMID 24811092 DOI: 10.1371/journal.pgen.1004327  1
2014 de Souza JE, Fonseca AF, Valieris R, Carraro DM, Wang JY, Kolodner RD, de Souza SJ. S-score: a scoring system for the identification and prioritization of predicted cancer genes. Plos One. 9: e94147. PMID 24710071 DOI: 10.1371/journal.pone.0094147  1
2014 Putnam CD, Pallis K, Hayes TK, Kolodner RD. DNA repair pathway selection caused by defects in TEL1, SAE2, and de novo telomere addition generates specific chromosomal rearrangement signatures. Plos Genetics. 10: e1004277. PMID 24699249 DOI: 10.1371/journal.pgen.1004277  1
2014 Srivatsan A, Bowen N, Kolodner RD. Mispair-specific recruitment of the Mlh1-Pms1 complex identifies repair substrates of the Saccharomyces cerevisiae Msh2-Msh3 complex Journal of Biological Chemistry. 289: 9352-9364. PMID 24550389 DOI: 10.1074/jbc.M114.552190  1
2014 Allen-Soltero S, Martinez SL, Putnam CD, Kolodner RD. A saccharomyces cerevisiae RNase H2 interaction network functions to suppress genome instability Molecular and Cellular Biology. 34: 1521-1534. PMID 24550002 DOI: 10.1128/MCB.00960-13  1
2014 Ragu S, Dardalhon M, Sharma S, Iraqui I, Buhagiar-Labarchéde G, Grondin V, Kienda G, Vernis L, Chanet R, Kolodner RD, Huang ME, Faye G. Loss of the thioredoxin reductase Trr1 suppresses the genomic instability of peroxiredoxin TSA1 mutants Plos One. 9. DOI: 10.1371/journal.pone.0108123  1
2013 Smith CE, Mendillo ML, Bowen N, Hombauer H, Campbell CS, Desai A, Putnam CD, Kolodner RD. Dominant mutations in S. cerevisiae PMS1 identify the Mlh1-Pms1 endonuclease active site and an exonuclease 1-independent mismatch repair pathway. Plos Genetics. 9: e1003869. PMID 24204293 DOI: 10.1371/journal.pgen.1003869  1
2013 Bowen N, Smith CE, Srivatsan A, Willcox S, Griffith JD, Kolodner RD. Reconstitution of long and short patch mismatch repair reactions using Saccharomyces cerevisiae proteins Proceedings of the National Academy of Sciences of the United States of America. 110: 18472-18477. PMID 24187148 DOI: 10.1073/pnas.1318971110  1
2013 Hura GL, Tsai CL, Claridge SA, Mendillo ML, Smith JM, Williams GJ, Mastroianni AJ, Alivisatos AP, Putnam CD, Kolodner RD, Tainer JA. DNA conformations in mismatch repair probed in solution by X-ray scattering from gold nanocrystals. Proceedings of the National Academy of Sciences of the United States of America. 110: 17308-13. PMID 24101514 DOI: 10.1073/pnas.1308595110  1
2013 Albuquerque CP, Wang G, Lee NS, Kolodner RD, Putnam CD, Zhou H. Distinct SUMO Ligases Cooperate with Esc2 and Slx5 to Suppress Duplication-Mediated Genome Rearrangements Plos Genetics. 9. PMID 23935535 DOI: 10.1371/journal.pgen.1003670  1
2013 Jaehnig EJ, Kuo D, Hombauer H, Ideker TG, Kolodner RD. Checkpoint kinases regulate a global network of transcription factors in response to DNA damage. Cell Reports. 4: 174-88. PMID 23810556 DOI: 10.1016/j.celrep.2013.05.041  1
2012 Putnam CD, Allen-Soltero SR, Martinez SL, Chan JE, Hayes TK, Kolodner RD. Bioinformatic identification of genes suppressing genome instability. Proceedings of the National Academy of Sciences of the United States of America. 109: E3251-9. PMID 23129647 DOI: 10.1073/pnas.1216733109  1
2012 Hargreaves VV, Putnam CD, Kolodner RD. Engineered disulfide-forming amino acid substitutions interfere with a conformational change in the mismatch recognition complex Msh2-Msh6 required for mismatch repair Journal of Biological Chemistry. 287: 41232-41244. PMID 23045530 DOI: 10.1074/jbc.M112.402495  1
2012 Chan JE, Kolodner RD. Rapid analysis of Saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification. Plos Genetics. 8: e1002539. PMID 22396658 DOI: 10.1371/journal.pgen.1002539  0.52
2012 Enserink JM, Kolodner RD. What makes the engine hum: Rad6, a cell cycle supercharger Cell Cycle. 11: 249-252. PMID 22214660 DOI: 10.4161/cc.11.2.19023  1
2012 Chan JE, Kolodner RD. Rapid analysis of saccharomyces cerevisiae genome rearrangements by multiplex ligation-dependent probe amplification Plos Genetics. 8. DOI: 10.1371/journal.pgen.1002539  1
2011 Hombauer H, Srivatsan A, Putnam CD, Kolodner RD. Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication. Science (New York, N.Y.). 334: 1713-6. PMID 22194578 DOI: 10.1126/science.1210770  1
2011 Hombauer H, Campbell CS, Smith CE, Desai A, Kolodner RD. Visualization of eukaryotic DNA mismatch repair reveals distinct recognition and repair intermediates Cell. 147: 1040-1053. PMID 22118461 DOI: 10.1016/j.cell.2011.10.025  1
2011 Zimmermann C, Chymkowitch P, Eldholm V, Putnam CD, Lindvall JM, Omerzu M, Bjørås M, Kolodner RD, Enserink JM. A chemical-genetic screen to unravel the genetic network of CDC28/CDK1 links ubiquitin and Rad6-Bre1 to cell cycle progression Proceedings of the National Academy of Sciences of the United States of America. 108: 18748-18753. PMID 22042866 DOI: 10.1073/pnas.1115885108  1
2011 Kolodner RD, Cleveland DW, Putnam CD. Cancer. Aneuploidy drives a mutator phenotype in cancer. Science (New York, N.Y.). 333: 942-3. PMID 21852477 DOI: 10.1126/science.1211154  1
2011 Chan JE, Kolodner RD. A genetic and structural study of genome rearrangements mediated by high copy repeat Ty1 elements Plos Genetics. 7. PMID 21637792 DOI: 10.1371/journal.pgen.1002089  1
2011 Hombauer H, Srivatsan A, Putnam CD, Kolodner RD. Mismatch repair, but not heteroduplex rejection, is temporally coupled to DNA replication Science. 334: 1713-1716. DOI: 10.1126/science.1210770  1
2010 Bandyopadhyay S, Mehta M, Kuo D, Sung MK, Chuang R, Jaehnig EJ, Bodenmiller B, Licon K, Copeland W, Shales M, Fiedler D, Dutkowski J, Guénolé A, van Attikum H, Shokat KM, ... Kolodner RD, et al. Rewiring of genetic networks in response to DNA damage. Science (New York, N.Y.). 330: 1385-9. PMID 21127252 DOI: 10.1126/science.1195618  0.8
2010 Putnam CD, Kolodner RD. Determination of gross chromosomal rearrangement rates. Cold Spring Harbor Protocols. 2010: pdb.prot5492. PMID 20810639  1
2010 Wang Y, Huang B, Edelmann L, Kolodner RD, Edelmann W. Genes essential for cell viability that are linked to tumor suppressor genes play a role in cancer susceptibility Cell Cycle. 9: 3144-3145. PMID 20703099 DOI: 10.4161/cc.9.16.12956  1
2010 Enserink JM, Kolodner RD. An overview of Cdk1-controlled targets and processes. Cell Division. 5: 11. PMID 20465793 DOI: 10.1186/1747-1028-5-11  1
2010 Putnam CD, Hayes TK, Kolodner RD. Post-replication repair suppresses duplication-mediated genome instability. Plos Genetics. 6: e1000933. PMID 20463880 DOI: 10.1371/journal.pgen.1000933  1
2010 Dowen JM, Putnam CD, Kolodner RD. Functional studies and homology modeling of Msh2-Msh3 predict that mispair recognition involves DNA bending and strand separation Molecular and Cellular Biology. 30: 3321-3328. PMID 20421420 DOI: 10.1128/MCB.01558-09  1
2010 Wang Y, Zhang W, Edelmann L, Kolodner RD, Kucherlapati R, Edelmann W. Cis lethal genetic interactions attenuate and alter p53 tumorigenesis. Proceedings of the National Academy of Sciences of the United States of America. 107: 5511-5. PMID 20212136 DOI: 10.1073/pnas.1001223107  1
2010 Mendillo ML, Putnam CD, Mo AO, Jamison JW, Li S, Woods VL, Kolodner RD. Probing DNA- and ATP-mediated conformational changes in the MutS family of mispair recognition proteins using deuterium exchange mass spectrometry Journal of Biological Chemistry. 285: 13170-13182. PMID 20181951 DOI: 10.1074/jbc.M110.108894  1
2010 Martinez SL, Kolodner RD. Functional analysis of human mismatch repair gene mutations identifies weak alleles and polymorphisms capable of polygenic interactions Proceedings of the National Academy of Sciences of the United States of America. 107: 5070-5075. PMID 20176959 DOI: 10.1073/pnas.1000798107  1
2010 Hargreaves VV, Shell SS, Mazur DJ, Hess MT, Kolodner RD. Interaction between the Msh2 and Msh6 nucleotide-binding sites in the Saccharomyces cerevisiae Msh2-Msh6 complex Journal of Biological Chemistry. 285: 9301-9310. PMID 20089866 DOI: 10.1074/jbc.M109.096388  1
2010 Enserink JM, Kolodner RD. An overview of Cdk1-controlled targets and processes Cell Division. 5. DOI: 10.1186/1747-1028-5-11  1
2010 Putnam CD, Kolodner RD. Determination of gross chromosomal rearrangement rates Cold Spring Harbor Protocols. 5. DOI: 10.1101/pdb.prot5492  1
2009 Mendillo ML, Hargreaves VV, Jamison JW, Mo AO, Li S, Putnam CD, Woods VL, Kolodner RD. A conserved MutS homolog connector domain interface interacts with MutL homologs Proceedings of the National Academy of Sciences of the United States of America. 106: 22223-22228. PMID 20080788 DOI: 10.1073/pnas.0912250106  1
2009 Mueller J, Gazzoli I, Bandipalliam P, Garber JE, Syngal S, Kolodner RD. Comprehensive molecular analysis of mismatch repair gene defects in suspected Lynch syndrome (hereditary nonpolyposis colorectal cancer) cases Cancer Research. 69: 7053-7061. PMID 19690142 DOI: 10.1158/0008-5472.CAN-09-0358  1
2009 Putnam CD, Hayes TK, Kolodner RD. Specific pathways prevent duplication-mediated genome rearrangements Nature. 460: 984-989. PMID 19641493 DOI: 10.1038/nature08217  1
2009 Pennaneach V, Kolodner RD. Stabilization of dicentric translocations through secondary rearrangements mediated by multiple mechanisms in S. cerevisiae Plos One. 4. PMID 19636429 DOI: 10.1371/journal.pone.0006389  1
2009 Kats ES, Enserink JM, Martinez S, Kolodner RD. The Saccharomyces cerevisiae Rad6 postreplication repair and Siz1/Srs2 homologous recombination-inhibiting pathways process DNA damage that arises in asf1 mutants Molecular and Cellular Biology. 29: 5226-5237. PMID 19635810 DOI: 10.1128/MCB.00894-09  1
2009 Iraqui I, Kienda G, Soeur J, Faye G, Baldacci G, Kolodner RD, Huang ME. Peroxiredoxin Tsa1 is the key peroxidase suppressing genome instability and protecting against cell death in Saccharomyces cerevisiae Plos Genetics. 5. PMID 19543365 DOI: 10.1371/journal.pgen.1000524  1
2009 Putnam CD, Jaehnig EJ, Kolodner RD. Perspectives on the DNA damage and replication checkpoint responses in Saccharomyces cerevisiae Dna Repair. 8: 974-982. PMID 19477695 DOI: 10.1016/j.dnarep.2009.04.021  1
2009 Enserink JM, Hombauer H, Huang ME, Kolodner RD. Cdc28/Cdk1 positively and negatively affects genome stability in S. cerevisiae Journal of Cell Biology. 185: 423-437. PMID 19398760 DOI: 10.1083/jcb.200811083  1
2008 Marinovic-Terzic I, Yoshioka-Yamashita A, Shimodaira H, Avdievich E, Hunton IC, Kolodner RD, Edelmann W, Wang JYJ. Apoptotic function of human PMS2 compromised by the nonsynonymous single-nucleotide polymorphic variant R20Q Proceedings of the National Academy of Sciences of the United States of America. 105: 13993-13998. PMID 18768816 DOI: 10.1073/pnas.0806435105  1
2008 Anderson JP, Mueller JL, Misaghi A, Anderson S, Sivagnanam M, Kolodner RD, Hoffman HM. Initial description of the human NLRP3 promoter Genes and Immunity. 9: 721-726. PMID 18719602 DOI: 10.1038/gene.2008.66  1
2008 Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, et al. Identification of EpCAM as the gene for congenital tufting enteropathy. Gastroenterology. 135: 429-37. PMID 18572020 DOI: 10.1053/j.gastro.2008.05.036  1
2008 Iraqui I, Faye G, Ragu S, Masurel-Heneman A, Kolodner RD, Huang ME. Human peroxiredoxin PrxI is an orthologue of yeast Tsa1, capable of suppressing genome instability in Saccharomyces cerevisiae Cancer Research. 68: 1055-1063. PMID 18281480 DOI: 10.1158/0008-5472.CAN-07-2683  1
2007 Kolodner RD, Mendillo ML, Putnam CD. Coupling distant sites in DNA during DNA mismatch repair Proceedings of the National Academy of Sciences of the United States of America. 104: 12953-12954. PMID 17664420 DOI: 10.1073/pnas.0705698104  1
2007 Harrington JM, Kolodner RD. Saccharomyces cerevisiae Msh2-Msh3 acts in repair of base-base mispairs Molecular and Cellular Biology. 27: 6546-6554. PMID 17636021 DOI: 10.1128/MCB.00855-07  1
2007 Shell SS, Putnam CD, Kolodner RD. Chimeric Saccharomyces cerevisiae Msh6 protein with an Msh3 mispair-binding domain combines properties of both proteins Proceedings of the National Academy of Sciences of the United States of America. 104: 10956-10961. PMID 17573527 DOI: 10.1073/pnas.0704148104  1
2007 Ragu S, Faye G, Iraqui I, Masurel-Heneman A, Kolodner RD, Huang ME. Oxygen metabolism and reactive oxygen species cause chromosomal rearrangements and cell death Proceedings of the National Academy of Sciences of the United States of America. 104: 9747-9752. PMID 17535927 DOI: 10.1073/pnas.0703192104  1
2007 Shell SS, Putnam CD, Kolodner RD. The N Terminus of Saccharomyces cerevisiae Msh6 Is an Unstructured Tether to PCNA Molecular Cell. 26: 565-578. PMID 17531814 DOI: 10.1016/j.molcel.2007.04.024  1
2007 Takahashi M, Shimodaira H, Andreutti-Zaugg C, Iggo R, Kolodner RD, Ishioka C. Functional analysis of human MLH1 variants using yeast and in vitro mismatch repair assays Cancer Research. 67: 4595-4604. PMID 17510385 DOI: 10.1158/0008-5472.CAN-06-3509  1
2007 Mendillo ML, Putnam CD, Kolodner RD. Escherichia coli MutS tetramerization domain structure reveals that stable dimers but not tetramers are essential for DNA mismatch repair in vivo Journal of Biological Chemistry. 282: 16345-16354. PMID 17426027 DOI: 10.1074/jbc.M700858200  1
2007 Aksentijevich I, Putnam CD, Remmers EF, Mueller JL, Le J, Kolodner RD, Moak Z, Chuang M, Austin F, Goldbach-Mansky R, Hoffman HM, Kastner DL. The clinical continuum of cryopyrinopathies: Novel CIAS1 mutations in North American patients and a new cryopyrin model Arthritis and Rheumatism. 56: 1273-1285. PMID 17393462 DOI: 10.1002/art.22491  1
2007 Hu Y, Rolfs A, Bhullar B, Murthy TV, Zhu C, Berger MF, Camargo AA, Kelley F, McCarron S, Jepson D, Richardson A, Raphael J, Moreira D, Taycher E, Zuo D, ... ... Kolodner RD, et al. Approaching a complete repository of sequence-verified protein-encoding clones for Saccharomyces cerevisiae. Genome Research. 17: 536-43. PMID 17322287 DOI: 10.1101/gr.6037607  1
2007 Lagerstedt Robinson K, Liu T, Vandrovcova J, Halvarsson B, Clendenning M, Frebourg T, Papadopoulos N, Kinzler KW, Vogelstein B, Peltomäki P, Kolodner RD, Nilbert M, Lindblom A. Lynch syndrome (hereditary nonpolyposis colorectal cancer) diagnostics Journal of the National Cancer Institute. 99: 291-299. PMID 17312306 DOI: 10.1093/jnci/djk051  1
2007 Vijayakumar S, Chapados BR, Schmidt KH, Kolodner RD, Tainer JA, Tomkinson AE. The C-terminal domain of yeast PCNA is required for physical and functional interactions with Cdc9 DNA ligase Nucleic Acids Research. 35: 1624-1637. PMID 17308348 DOI: 10.1093/nar/gkm006  1
2006 Smolka MB, Chen SH, Maddox PS, Enserink JM, Albuquerque CP, Wei XX, Desai A, Kolodner RD, Zhou H. An FHA domain-mediated protein interaction network of Rad53 reveals its role in polarized cell growth. The Journal of Cell Biology. 175: 743-53. PMID 17130285 DOI: 10.1083/jcb.200605081  1
2006 Enserink JM, Smolka MB, Zhou H, Kolodner RD. Checkpoint proteins control morphogenetic events during DNA replication stress in Saccharomyces cerevisiae. The Journal of Cell Biology. 175: 729-41. PMID 17130284 DOI: 10.1083/jcb.200605080  1
2006 Schmidt KH, Kolodner RD. Suppression of spontaneous genome rearrangements in yeast DNA helicase mutants Proceedings of the National Academy of Sciences of the United States of America. 103: 18196-18201. PMID 17114288 DOI: 10.1073/pnas.0608566103  1
2006 Chen CC, Motegi A, Hasegawa Y, Myung K, Kolodner R, D'Andrea A. Genetic analysis of ionizing radiation-induced mutagenesis in Saccharomyces cerevisiae reveals TransLesion Synthesis (TLS) independent of PCNA K164 SUMOylation and ubiquitination Dna Repair. 5: 1475-1488. PMID 16990054 DOI: 10.1016/j.dnarep.2006.07.007  1
2006 Schmidt KH, Wu J, Kolodner RD. Control of translocations between highly diverged genes by Sgs1, the Saccharomyces cerevisiae homolog of the Bloom's syndrome protein Molecular and Cellular Biology. 26: 5406-5420. PMID 16809776 DOI: 10.1128/MCB.00161-06  1
2006 Cooper AA, Gitler AD, Cashikar A, Haynes CM, Hill KJ, Bhullar B, Liu K, Xu K, Strathearn KE, Liu F, Cao S, Caldwell KA, Caldwell GA, Marsischky G, Kolodner RD, et al. Alpha-synuclein blocks ER-Golgi traffic and Rab1 rescues neuron loss in Parkinson's models. Science (New York, N.Y.). 313: 324-8. PMID 16794039 DOI: 10.1126/science.1129462  1
2006 Schmidt KH, Pennaneach V, Putnam CD, Kolodner RD. Analysis of Gross-Chromosomal Rearrangements in Saccharomyces cerevisiae Methods in Enzymology. 409: 462-476. PMID 16793418 DOI: 10.1016/S0076-6879(05)09027-0  1
2006 Mazur DJ, Mendillo ML, Kolodner RD. Inhibition of Msh6 ATPase Activity by Mispaired DNA Induces a Msh2(ATP)-Msh6(ATP) State Capable of Hydrolysis-Independent Movement along DNA Molecular Cell. 22: 39-49. PMID 16600868 DOI: 10.1016/j.molcel.2006.02.010  1
2006 Kats ES, Albuquerque CP, Zhou H, Kolodner RD. Checkpoint functions are required for normal S-phase progression in Saccharomyces cerevisiae RCAF- and CAF-I-defective mutants Proceedings of the National Academy of Sciences of the United States of America. 103: 3710-3715. PMID 16501045 DOI: 10.1073/pnas.0511102103  1
2006 Pennaneach V, Putnam CD, Kolodner RD. Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae Molecular Microbiology. 59: 1357-1368. PMID 16468981 DOI: 10.1111/j.1365-2958.2006.05026.x  1
2006 Hess MT, Mendillo ML, Mazur DJ, Kolodner RD. Biochemical basis for dominant mutations in the Saccharomyces cerevisiae MSH6 gene Proceedings of the National Academy of Sciences of the United States of America. 103: 558-563. PMID 16407100 DOI: 10.1073/pnas.0510078103  1
2005 Sadler GR, Peterson M, Wasserman L, Mills P, Malcarne VL, Rock C, Ancoli-Israel S, Moore A, Weldon RN, Garcia T, Kolodner RD. Recruiting research participants at community education sites. Journal of Cancer Education : the Official Journal of the American Association For Cancer Education. 20: 235-9. PMID 16497136 DOI: 10.1207/s15430154jce2004_12  1
2005 Putnam CD, Pennaneach V, Kolodner RD. Saccharomyces cerevisiae as a model system to define the chromosomal instability phenotype Molecular and Cellular Biology. 25: 7226-7238. PMID 16055731 DOI: 10.1128/MCB.25.16.7226-7238.2005  1
2005 Smolka MB, Albuquerque CP, Chen SH, Schmidt KH, Wei XX, Kolodner RD, Zhou H. Dynamic changes in protein-protein interaction and protein phosphorylation probed with amine-reactive isotope tag. Molecular & Cellular Proteomics : McP. 4: 1358-69. PMID 15972895 DOI: 10.1074/mcp.M500115-MCP200  1
2005 Wang Y, Putnam CD, Kane MF, Zhang W, Edelmann L, Russell R, Carrión DV, Chin L, Kucherlapati R, Kolodner RD, Edelmann W. Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice. Nature Genetics. 37: 750-5. PMID 15965476 DOI: 10.1038/ng1587  1
2005 Mendillo ML, Mazur DJ, Kolodner RD. Analysis of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 and MLH1-PMS1 complexes with DNA using a reversible DNA end-blocking system Journal of Biological Chemistry. 280: 22245-22257. PMID 15811858 DOI: 10.1074/jbc.M407545200  1
2005 Smith S, Gupta A, Kolodner RD, Myung K. Suppression of gross chromosomal rearrangements by the multiple functions of the Mre11-Rad50-Xrs2 complex in Saccharomyces cerevisiae Dna Repair. 4: 606-617. PMID 15811632 DOI: 10.1016/j.dnarep.2005.01.004  1
2005 Huang ME, Kolodner RD. A biological network in Saccharomyces cerevisiae prevents the deleterious effects of endogenous oxidative DNA damage Molecular Cell. 17: 709-720. PMID 15749020 DOI: 10.1016/j.molcel.2005.02.008  1
2004 Tajima A, Hess MT, Cabrera BL, Kolodner RD, Carethers JM. The mismatch repair complex hMutSα recognizes 5-fluorouracil-modified DNA: Implications for chemosensitivity and resistance Gastroenterology. 127: 1678-1684. PMID 15578504 DOI: 10.1053/j.gastro.2004.10.001  1
2004 Myung K, Smith S, Kolodner RD. Mitotic checkpoint function in the formation of gross chromosomal rearrangements in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 101: 15980-15985. PMID 15514023 DOI: 10.1073/pnas.0407010101  1
2004 Putnam CD, Pennaneach V, Kolodner RD. Chromosome healing through terminal deletions generated by de novo telomere additions in Saccharomyces cerevisiae Proceedings of the National Academy of Sciences of the United States of America. 101: 13262-13267. PMID 15328403 DOI: 10.1073/pnas.0405443101  1
2004 Yang G, Scherer SJ, Shell SS, Yang K, Kim M, Lipkin M, Kucherlapati R, Kolodner RD, Edelmann W. Dominant effects of an Msh6 missense mutation on DNA repair and cancer susceptibility. Cancer Cell. 6: 139-50. PMID 15324697 DOI: 10.1016/j.ccr.2004.06.024  1
2004 Pennaneach V, Kolodner RD. Recombination and the Tel1 and Mec1 checkpoints differentially effect genome rearrangements driven by telomere dysfunction in yeast Nature Genetics. 36: 612-617. PMID 15133512 DOI: 10.1038/ng1359  1
2004 Tornaletti S, Maeda LS, Kolodner RD, Hanawalt PC. Effect of 8-oxoguanine on transcription elongation by T7 RNA polymerase and mammalian RNA polymerase II. Dna Repair. 3: 483-94. PMID 15084310 DOI: 10.1016/j.dnarep.2004.01.003  1
2004 Mazina OM, Mazin AV, Nakagawa T, Kolodner RD, Kowalczykowski SC. Saccharomyces cerevisiae Mer3 helicase stimulates 3′-5′ heteroduplex extension by Rad51: Implications for crossover control in meiotic recombination Cell. 117: 47-56. PMID 15066281 DOI: 10.1016/S0092-8674(04)00294-6  1
2004 Schmidt KH, Kolodner RD. Requirement of Rrm3 Helicase for Repair of Spontaneous DNA Lesions in Cells Lacking Srs2 or Sgs1 Helicase Molecular and Cellular Biology. 24: 3213-3226. PMID 15060145 DOI: 10.1128/MCB.24.8.3213-3226.2004  1
2004 Bandipalliam P, Garber J, Syngal S, Kolodner RD. Clinical Presentation Correlates with the Type of Mismatch Repair Gene Involved in Hereditary Nonpolyposis Colon Cancer [3] Gastroenterology. 126: 936-937. PMID 14988860 DOI: 10.1053/j.gastro.2004.01.038  1
2003 Gazzoli I, Kolodner RD. Regulation of the Human MSH6 Gene by the Sp1 Transcription Factor and Alteration of Promoter Activity and Expression by Polymorphisms Molecular and Cellular Biology. 23: 7992-8007. PMID 14585961 DOI: 10.1128/MCB.23.22.7992-8007.2003  1
2003 Huang ME, Rio AG, Nicolas A, Kolodner RD. A genomewide screen in Saccharomyces cerevisiae for genes that suppress the accumulation of mutations. Proceedings of the National Academy of Sciences of the United States of America. 100: 11529-34. PMID 12972632 DOI: 10.1073/pnas.2035018100  1
2003 Myung K, Pennaneach V, Kats ES, Kolodner RD. Saccharomyces cerevisiae chromatin-assembly factors that act during DNA replication function in the maintenance of genome stability Proceedings of the National Academy of Sciences of the United States of America. 100: 6640-6645. PMID 12750463 DOI: 10.1073/pnas.1232239100  1
2003 Kantake N, Sugiyama T, Kolodner RD, Kowalczykowski SC. The recombination-deficient mutant RPA (rfa1-t11) is displaced slowly from single-stranded DNA by Rad51 protein Journal of Biological Chemistry. 278: 23410-23417. PMID 12697761 DOI: 10.1074/jbc.M302995200  1
2003 Wei K, Clark AB, Wong E, Kane MF, Mazur DJ, Parris T, Kolas NK, Russell R, Hou H, Kneitz B, Yang G, Kunkel TA, Kolodner RD, Cohen PE, Edelmann W. Inactivation of exonuclease I in mice results in DNA mismatch repair defects, increased cancer susceptibility, and male and female sterility Genes and Development. 17: 603-614. PMID 12629043 DOI: 10.1101/gad.1060603  1
2003 Shimodaira H, Yoshioka-Yamashita A, Kolodner RD, Wang JYJ. Interaction of mismatch repair protein PMS2 and the p53-related transcription factor p73 in apoptosis response to cisplatin Proceedings of the National Academy of Sciences of the United States of America. 100: 2420-2425. PMID 12601175 DOI: 10.1073/pnas.0438031100  1
2003 Myung K, Kolodner RD. Induction of genome instability by DNA damage in Saccharomyces cerevisiae Dna Repair. 2: 243-258. PMID 12547388 DOI: 10.1016/S1568-7864(02)00216-1  1
2003 Hoffman HM, Gregory SG, Mueller JL, Tresierras M, Broide DH, Wanderer AA, Kolodner RD. Fine structure mapping of CIAS1: Identification of an ancestral haplotype and a common FCAS mutation, L353P Human Genetics. 112: 209-216. PMID 12522564  1
2003 Jagmohan-Changur S, Poikonen T, Vilkki S, Launonen V, Wikman F, Orntoft TF, Møller P, Vasen H, Tops C, Kolodner RD, Mecklin JP, Järvinen H, Bevan S, Houlston RS, Aaltonen LA, et al. EXO1 variants occur commonly in normal population: Evidence against a role in hereditary nonpolyposis colorectal cancer Cancer Research. 63: 154-158. PMID 12517792  1
2003 Noirot P, Gupta RC, Radding CM, Kolodner RD. Hallmarks of homology recognition by RecA-like recombinases are exhibited by the unrelated Escherichia coli RecT protein Embo Journal. 22: 324-334. PMID 12514138 DOI: 10.1093/emboj/cdg027  1
2003 Lau PJ, Kolodner RD. Transfer of the MSH2·MSH6 complex from proliferating cell nuclear antigen to mispaired bases in DNA Journal of Biological Chemistry. 278: 14-17. PMID 12435741 DOI: 10.1074/jbc.C200627200  1
2002 Schmidt KH, Derry KL, Kolodner RD. Saccharomyces cerevisiae RRM3, a 5′ to 3′ DNA helicase, physically interacts with proliferating cell nuclear antigen Journal of Biological Chemistry. 277: 45331-45337. PMID 12239216 DOI: 10.1074/jbc.M207263200  1
2002 Lau PJ, Flores-Rozas H, Kolodner RD. Isolation and characterization of new proliferating cell nuclear antigen (POL30) mutator mutants that are defective in DNA mismatch repair Molecular and Cellular Biology. 22: 6669-6680. PMID 12215524 DOI: 10.1128/MCB.22.19.6669-6680.2002  1
2002 Kolodner RD, Putnam CD, Myung K. Maintenance of genome stability in Saccharomyces cerevisiae Science. 297: 552-557. PMID 12142524 DOI: 10.1126/science.1075277  1
2002 Gazzoli I, Loda M, Garber J, Syngal S, Kolodner RD. A hereditary nonpolyposis colorectal carcinoma case associated with hypermethylation of the MLH1 gene in normal tissue and loss of heterozygosity of the unmethylated allele in the resulting microsatellite instability-high tumor. Cancer Research. 62: 3925-8. PMID 12124320  1
2002 Kucherlapati M, Yang K, Kuraguchi M, Zhao J, Lia M, Heyer J, Kane MF, Fan K, Russell R, Brown AM, Kneitz B, Edelmann W, Kolodner RD, Lipkin M, Kucherlapati R. Haploinsufficiency of Flap endonuclease (Fen1) leads to rapid tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 99: 9924-9. PMID 12119409 DOI: 10.1073/pnas.152321699  1
2002 Wahlberg SS, Schmeits J, Thomas G, Loda M, Garber J, Syngal S, Kolodner RD, Fox E. Evaluation of microsatellite instability and immunohistochemistry for the prediction of germ-line MSH2 and MLH1 mutations in hereditary nonpolyposis colon cancer families. Cancer Research. 62: 3485-92. PMID 12067992  1
2002 Nakagawa T, Kolodner RD. The MER3 DNA helicase catalyzes the unwinding of Holliday junctions Journal of Biological Chemistry. 277: 28019-28024. PMID 12039965 DOI: 10.1074/jbc.M204165200  1
2002 Hess MT, Gupta RD, Kolodner RD. Dominant Saccharomyces cerevisiae msh6 mutations cause increased mispair binding and decreased dissociation from mispairs by Msh2-Msh6 in the presence of ATP. The Journal of Biological Chemistry. 277: 25545-53. PMID 11986324 DOI: 10.1074/jbc.M202282200  1
2002 Nakagawa T, Kolodner RD. Saccharomyces cerevisiae Mer3 is a DNA helicase involved in meiotic crossing over. Molecular and Cellular Biology. 22: 3281-91. PMID 11971962 DOI: 10.1128/MCB.22.10.3281-3291.2002  1
2002 Myung K, Kolodner RD. Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomyces cerevisiae. Proceedings of the National Academy of Sciences of the United States of America. 99: 4500-7. PMID 11917116 DOI: 10.1073/pnas.062702199  1
2001 Kuraguchi M, Yang K, Wong E, Avdievich E, Fan K, Kolodner RD, Lipkin M, Brown AM, Kucherlapati R, Edelmann W. The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis. Cancer Research. 61: 7934-42. PMID 11691815  1
2001 Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD. Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nature Genetics. 29: 301-5. PMID 11687797 DOI: 10.1038/ng756  1
2001 Amin NS, Nguyen MN, Oh S, Kolodner RD. exo1-Dependent mutator mutations: model system for studying functional interactions in mismatch repair. Molecular and Cellular Biology. 21: 5142-55. PMID 11438669 DOI: 10.1128/MCB.21.15.5142-5155.2001  1
2001 Myung K, Chen C, Kolodner RD. Multiple pathways cooperate in the suppression of genome instability in Saccharomyces cerevisiae. Nature. 411: 1073-6. PMID 11429610 DOI: 10.1038/35082608  1
2001 Nakagawa T, Flores-Rozas H, Kolodner RD. The MER3 helicase involved in meiotic crossing over is stimulated by single-stranded DNA-binding proteins and unwinds DNA in the 3' to 5' direction. The Journal of Biological Chemistry. 276: 31487-93. PMID 11376001 DOI: 10.1074/jbc.M104003200  1
2001 Myung K, Datta A, Kolodner RD. Suppression of spontaneous chromosomal rearrangements by S phase checkpoint functions in Saccharomyces cerevisiae. Cell. 104: 397-408. PMID 11239397 DOI: 10.1016/S0092-8674(01)00227-6  1
2001 Myung K, Datta A, Chen C, Kolodner RD. SGS1, the Saccharomyces cerevisiae homologue of BLM and WRN, suppresses genome instability and homeologous recombination. Nature Genetics. 27: 113-6. PMID 11138010 DOI: 10.1038/83673  1
2000 Flores-Rozas H, Clark D, Kolodner RD. Proliferating cell nuclear antigen and Msh2p-Msh6p interact to form an active mispair recognition complex. Nature Genetics. 26: 375-8. PMID 11062484 DOI: 10.1038/81708  1
2000 Kolodner RD. Guarding against mutation. Nature. 407: 687, 689. PMID 11048703 DOI: 10.1038/35037701  1
2000 Datta A, Schmeits JL, Amin NS, Lau PJ, Myung K, Kolodner RD. Checkpoint-dependent activation of mutagenic repair in Saccharomyces cerevisiae pol3-01 mutants. Molecular Cell. 6: 593-603. PMID 11030339  1
2000 Peel DJ, Ziogas A, Fox EA, Gildea M, Laham B, Clements E, Kolodner RD, Anton-Culver H. Characterization of hereditary nonpolyposis colorectal cancer families from a population-based series of cases. Journal of the National Cancer Institute. 92: 1517-22. PMID 10995807  1
2000 Syngal S, Fox EA, Eng C, Kolodner RD, Garber JE. Sensitivity and specificity of clinical criteria for hereditary non-polyposis colorectal cancer associated mutations in MSH2 and MLH1. Journal of Medical Genetics. 37: 641-5. PMID 10978352  1
2000 Kneitz B, Cohen PE, Avdievich E, Zhu L, Kane MF, Hou H, Kolodner RD, Kucherlapati R, Pollard JW, Edelmann W. MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice. Genes & Development. 14: 1085-97. PMID 10809667  1
2000 Flores-Rozas H, Kolodner RD. Links between replication, recombination and genome instability in eukaryotes. Trends in Biochemical Sciences. 25: 196-200. PMID 10754554 DOI: 10.1016/S0968-0004(00)01568-1  1
2000 Hoffman HM, Wright FA, Broide DH, Wanderer AA, Kolodner RD. Identification of a locus on chromosome 1q44 for familial cold urticaria. American Journal of Human Genetics. 66: 1693-8. PMID 10741953 DOI: 10.1086/302874  1
2000 Edelmann W, Umar A, Yang K, Heyer J, Kucherlapati M, Lia M, Kneitz B, Avdievich E, Fan K, Wong E, Crouse G, Kunkel T, Lipkin M, Kolodner RD, Kucherlapati R. The DNA mismatch repair genes Msh3 and Msh6 cooperate in intestinal tumor suppression. Cancer Research. 60: 803-7. PMID 10706084  1
2000 Merker JD, Datta A, Kolodner RD, Petes TD. The yeast HSM3 gene is not involved in DNA mismatch repair in rapidly dividing cells. Genetics. 154: 491-3. PMID 10681182  1
2000 Wang JYJ, Kolodner RD. Keystone Symposia on Molecular and Cellular Biology: 'The molecular basis of cancer' - Organizers: Carol L. Prives and George F. Vande Woude, Taos, NM, 15-21 March 1999 Biochimica Et Biophysica Acta - Reviews On Cancer. 1470: R21-R28. PMID 10656992 DOI: 10.1016/S0304-419X(99)00036-0  1
2000 Das Gupta R, Kolodner RD. Novel dominant mutations in Saccharomyces cerevisiae MSH6 Nature Genetics. 24: 53-56. PMID 10615127 DOI: 10.1038/71684  1
1999 Nakagawa T, Datta A, Kolodner RD. Multiple functions of MutS- and MutL-related heterocomplexes Proceedings of the National Academy of Sciences of the United States of America. 96: 14186-14188. PMID 10588673 DOI: 10.1073/pnas.96.25.14186  1
1999 Kolodner RD, Tytell JD, Schmeits JL, Kane MF, Gupta RD, Weger J, Wahlberg S, Fox EA, Peel D, Ziogas A, Garber JE, Syngal S, Anton-Culver H, Li FP. Germ-line msh6 mutations in colorectal cancer families. Cancer Research. 59: 5068-74. PMID 10537275  1
1999 Chen C, Merrill BJ, Lau PJ, Holm C, Kolodner RD. Saccharomyces cerevisiae pol30 (proliferating cell nuclear antigen) mutations impair replication fidelity and mismatch repair. Molecular and Cellular Biology. 19: 7801-15. PMID 10523669  1
1999 Ni TT, Marsischky GT, Kolodner RD. MSH2 and MSH6 are required for removal of adenine misincorporated opposite 8-oxo-guanine in S. cerevisiae. Molecular Cell. 4: 439-44. PMID 10518225 DOI: 10.1016/S1097-2765(00)80346-9  1
1999 Verma L, Kane MF, Brassett C, Schmeits J, Evans DGR, Kolodner RD, Maher ER. Mononucleotide microsatellite instability and germline MSH6 mutation analysis in early onset colorectal cancer Journal of Medical Genetics. 36: 678-682. PMID 10507723  1
1999 Marsischky GT, Kolodner RD. Biochemical characterization of the interaction between the Saccharomyces cerevisiae MSH2-MSH6 complex and mispaired bases in DNA Journal of Biological Chemistry. 274: 26668-26682. PMID 10480869 DOI: 10.1074/jbc.274.38.26668  1
1999 Chen C, Kolodner RD. Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants Nature Genetics. 23: 81-85. PMID 10471504 DOI: 10.1038/12687  1
1999 Syngal S, Fox EA, Li C, Dovidio M, Eng C, Kolodner RD, Garber JE. Interpretation of genetic test results for hereditary nonpolyposis colorectal cancer: implications for clinical predisposition testing. Jama. 282: 247-53. PMID 10422993 DOI: 10.1001/jama.282.3.247  1
1999 Kolodner RD, Marsischky GT. Eukaryotic DNA mismatch repair Current Opinion in Genetics and Development. 9: 89-96. PMID 10072354 DOI: 10.1016/S0959-437X(99)80013-6  1
1999 Marsischky GT, Lee S, Griffith J, Kolodner RD. 'Saccharomyces cerevisiae MSH2/6 complex interacts with Holliday junctions and facilitates their cleavage by phage resolution enzymes Journal of Biological Chemistry. 274: 7200-7206. PMID 10066781 DOI: 10.1074/jbc.274.11.7200  1
1999 Cunningham JM, Christensen ER, Tester DJ, Kim CY, Roche PC, Burgart LJ, Thibodeau SN, Herman JG, Umar A, Polyak J, Graff JR, Ahuja N, Issa JP, Markowitz S, Willson JK, ... ... Kolodner RD, et al. Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability; Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Chemtracts. 12: 708-713.  1
1998 Smith WM, Van Orsouw NJ, Fox EA, Kolodner RD, Vijg J, Eng C. Accurate, high-throughput "snapshot" detection of hMLH1 mutations by two-dimensional DNA electrophoresis. Genetic Testing. 2: 43-53. PMID 10464596  1
1998 Bertrand P, Tishkoff DX, Filosi N, Dasgupta R, Kolodner RD. Physical interaction between components of DNA mismatch repair and nucleotide excision repair Proceedings of the National Academy of Sciences of the United States of America. 95: 14278-14283. PMID 9826691 DOI: 10.1073/pnas.95.24.14278  1
1998 Tishkoff DX, Amin NS, Viars CS, Arden KC, Kolodner RD. Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination Cancer Research. 58: 5027-5031. PMID 9823303  1
1998 Winand NJ, Panzer JA, Kolodner RD. Cloning and characterization of the human and Caenorhabditis elegans homologs of the Saccharomyces cerevisiae MSH5 gene. Genomics. 53: 69-80. PMID 9787078 DOI: 10.1006/geno.1998.5447  1
1998 Flores-Rozas H, Kolodner RD. The Saccharomyces cerevisiae MLH3 gene functions in MSH3-dependent suppression of frameshift mutations Proceedings of the National Academy of Sciences of the United States of America. 95: 12404-12409. PMID 9770499 DOI: 10.1073/pnas.95.21.12404  1
1998 Lee SE, Moore JK, Holmes A, Umezu K, Kolodner RD, Haber JE. Saccharomyces Ku70, Mre11/Rad50, and RPA proteins regulate adaptation to G2/M arrest after DNA damage Cell. 94: 399-409. PMID 9708741 DOI: 10.1016/S0092-8674(00)81482-8  1
1998 Chen C, Umezu K, Kolodner RD. Chromosomal rearrangements occur in S. Cerevisiae rfa1 mutator mutants due to mutagenic lesions processed by double-strand-break repair Molecular Cell. 2: 9-22. PMID 9702187  1
1998 Shimodaira H, Filosi N, Shibata H, Suzuki T, Radice P, Kanamaru R, Friend SH, Kolodner RD, Ishioka C. Functional analysis of human MLH1 mutations in Saccharomyces cerevisiae Nature Genetics. 19: 384-389. PMID 9697702 DOI: 10.1038/1277  1
1998 Page AM, Davis K, Molineux C, Kolodner RD, Johnson AW. Mutational analysis of exoribonuclease I from Saccharomyces cerevisiae Nucleic Acids Research. 26: 3707-3716. PMID 9685486 DOI: 10.1093/nar/26.16.3707  1
1998 Herman JG, Umar A, Polyak K, Graff JR, Ahuja N, Issa JPJ, Markowitz S, Willson JKV, Hamilton SR, Kinzler KW, Kane MF, Kolodner RD, Vogelstein B, Kunkel TA, Baylin SB. Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma Proceedings of the National Academy of Sciences of the United States of America. 95: 6870-6875. PMID 9618505 DOI: 10.1073/pnas.95.12.6870  1
1998 Noirot P, Kolodner RD. DNA strand invasion promoted by Escherichia coli RecT protein Journal of Biological Chemistry. 273: 12274-12280. PMID 9575178 DOI: 10.1074/jbc.273.20.12274  1
1998 Umezu K, Sugawara N, Chen C, Haber JE, Kolodner RD. Genetic analysis of yeast RPA1 reveals its multiple functions in DNA metabolism Genetics. 148: 989-1005. PMID 9539419  1
1997 Umar A, Koi M, Risinger JI, Glaab WE, Tindall KR, Kolodner RD, Boland CR, Barrett JC, Kunkel TA. Correction of hypermutability, N-Methyl-N'-nitro-N-nitrosoguanidine resistance, and defective dna mismatch repair by introducing chromosome 2 into human tumor cells with mutations in MSH2 and MSH6 Cancer Research. 57: 3949-3955. PMID 9307278  1
1997 Tishkoff DX, Boerger AL, Bertrand P, Filosi N, Gaida GM, Kane MF, Kolodner RD. Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2. Proceedings of the National Academy of Sciences of the United States of America. 94: 7487-92. PMID 9207118 DOI: 10.1073/pnas.94.14.7487  1
1997 Fiorentini P, Huang KN, Tishkoff DX, Kolodner RD, Symington LS. Exonuclease I of Saccharomyces cerevisiae functions in mitotic recombination in vivo and in vitro. Molecular and Cellular Biology. 17: 2764-73. PMID 9111347  1
1997 Wahlberg SS, Nyström-Lahti M, Kane MF, Kolodner RD, Peltomäki P, Lindblom A. Low frequency of hMSH2 mutations in Swedish HNPCC families International Journal of Cancer. Journal International Du Cancer. 74: 134-137. PMID 9036882  1
1997 Alani E, Lee S, Kane MF, Griffith J, Kolodner RD. Saccharomyces cerevisiae MSH2, a mispaired base recognition protein, also recognizes holliday junctions in DNA Journal of Molecular Biology. 265: 289-301. PMID 9018043 DOI: 10.1006/jmbi.1996.0743  1
1997 Tishkoff DX, Filosi N, Gaida GM, Kolodner RD. A novel mutation avoidance mechanism dependent on S. cerevisiae RAD27 is distinct from DNA mismatch repair Cell. 88: 253-263. PMID 9008166 DOI: 10.1016/S0092-8674(00)81846-2  1
1996 Tonin P, Weber B, Offit K, Couch F, Rebbeck TR, Neuhausen S, Godwin AK, Daly M, Wagner-Costalos J, Berman D, Grana G, Fox E, Kane MF, Kolodner RD, Krainer M, et al. Frequency of recurrent BRCA1 and BRCA2 mutations in Ashkenazi Jewish breast cancer families Nature Medicine. 2: 1179-1183. PMID 8898735 DOI: 10.1038/nm1196-1179  1
1996 Edelmann W, Cohen PE, Kane M, Lau K, Morrow B, Bennett S, Umar A, Kunkel T, Cattoretti G, Chaganti R, Pollard JW, Kolodner RD, Kucherlapati R. Meiotic pachytene arrest in MLH1-deficient mice. Cell. 85: 1125-34. PMID 8674118 DOI: 10.1016/S0092-8674(00)81312-4  1
1995 Børresen AL, Lothe RA, Meling GI, Lystad S, Morrison P, Lipford J, Kane MF, Rognum TO, Kolodner RD. Somatic mutations in the hMSH2 gene in microsatellite unstable colorectal carcinomas Human Molecular Genetics. 4: 2065-2072. PMID 8589682 DOI: 10.1093/hmg/4.11.2065  1
1995 Kolodner RD. Mismatch repair: mechanisms and relationship to cancer susceptibility Trends in Biochemical Sciences. 20: 397-401. PMID 8533151 DOI: 10.1016/S0968-0004(00)89087-8  1
1995 Boyer JC, Umar A, Risinger JI, Lipford JR, Kane M, Yin S, Barrett JC, Kolodner RD, Kunkel TA. Microsatellite instability, mismatch repair deficiency, and genetic defects in human cancer cell lines Cancer Research. 55: 6063-6070. PMID 8521394  1
1995 Kolodner RD, Hall NR, Lipford J, Kane MF, Morrison PT, Finan PJ, Burn J, Chapman P, Earabino C, Merchant E, Bishop DT. Structure of the human MLH1 locus and analysis of a large hereditary nonpolyposis colorectal carcinoma kindred for mlh1 mutations Cancer Research. 55: 242-248. PMID 7812952  1
1995 Heyer WD, Johnson AW, Reinhart U, Kolodner RD. Regulation and intracellular localization of Saccharomyces cerevisiae strand exchange protein 1 (Sep1/Xrn1/Kem1), a multifunctional exonuclease Molecular and Cellular Biology. 15: 2728-2736. PMID 7739553  1
1995 Johnson AW, Kolodner RD. Synthetic lethality of sep1 (xrn1) ski2 and sep1 (xrn1) ski3 mutants of Saccharomyces cerevisiae is independent of killer virus and suggests a general role for these genes in translation control Molecular and Cellular Biology. 15: 2719-2727. PMID 7739552  1
1995 Tishkoff DX, Rockmill B, Roeder GS, Kolodner RD. The sep1 mutant of Saccharomyces cerevisiae arrests in pachytene and is deficient in meiotic recombination. Genetics. 139: 495-509. PMID 7713413  1
1995 Fishel R, Kolodner RD. Identification of mismatch repair genes and their role in the development of cancer Current Opinion in Genetics and Development. 5: 382-395. PMID 7549435 DOI: 10.1016/0959-437X(95)80055-7  1
1994 Hall SD, Kolodner RD. Homologous pairing and strand exchange promoted by the Escherichia coli RecT protein Proceedings of the National Academy of Sciences of the United States of America. 91: 3205-3209. PMID 8159725  1
1994 Johnson AW, Kolodner RD. Characterization of the interaction of Saccharomyces cerevisiae strand exchange protein 1 with DNA Journal of Biological Chemistry. 269: 3673-3681. PMID 8106412  1
1994 Johnson AW, Kolodner RD. The activity of the Saccharomyces cerevisiae strand exchange protein 1 intrinsic exonuclease during joint molecule formation Journal of Biological Chemistry. 269: 3664-3672. PMID 8106411  1
1994 Prolla TA, Pang Q, Alani E, Kolodner RD, Liskay RM. MLH1, PMS1, and MSH2 interactions during the initiation of DNA mismatch repair in yeast Science. 265: 1091-1093. PMID 8066446  1
1994 Alani E, Reenan RA, Kolodner RD. Interaction between mismatch repair and genetic recombination in Saccharomyces cerevisiae. Genetics. 137: 19-39. PMID 8056309  1
1994 Umezu K, Kolodner RD. Protein interactions in genetic recombination in Escherichia coli. Interactions involving RecO and RecR overcome the inhibition of RecA by single-stranded DNA-binding protein Journal of Biological Chemistry. 269: 30005-30013. PMID 7962001  1
1994 Chi NW, Kolodner RD. The effect of DNA mismatches on the ATPase activity of MSH1, a protein in yeast mitochondria that recognizes DNA mismatches Journal of Biological Chemistry. 269: 29993-29997. PMID 7961999  1
1994 Chi NW, Kolodner RD. Purification and characterization of MSH1, a yeast mitochondrial protein that binds to DNA mismatches Journal of Biological Chemistry. 269: 29984-29992. PMID 7961998  1
1994 Hall NR, Taylor GR, Finan PJ, Kolodner RD, Bodmer WF, Cottrell SE, Frayling I, Bishop DT. Intron splice acceptor site sequence variation in the hereditary non-polyposis colorectal cancer gene hMSH2. European Journal of Cancer (Oxford, England : 1990). 30: 1550-2. PMID 7833117 DOI: 10.1016/0959-8049(94)00326-Z  1
1994 Kolodner RD, Alani E. Mismatch repair and cancer susceptibility Current Opinion in Biotechnology. 5: 585-594. PMID 7765740 DOI: 10.1016/0958-1669(94)90079-5  1
1994 Kolodner RD, Hall NR, Lipford J, Kane MF, Rao MRS, Morrison P, Wirth L, Finan PJ, Burn J, Chapman P, Earabino C, Merchant E, Bishop DT. Structure of the Human MSH2 Locus and Analysis of Two Muir-Torre Kindreds for msh2 Mutations Genomics. 24: 516-526. PMID 7713503 DOI: 10.1006/geno.1994.1661  1
1994 Kolodner RD, Hall NR, Lipford J, Kane MF, Rao MRS, Morrison P, Wirth L, Finan PJ, Burn J, Chapman P, Earabino C, Merchant E, Bishop DT, Garber J, Bronner CE, et al. Human mismatch repair genes and their association with hereditary non- polyposis colon cancer Cold Spring Harbor Symposia On Quantitative Biology. 59: 331-338. PMID 7587085  1
1993 Umezu K, Chi NW, Kolodner RD. Biochemical interaction of the Escherichia coli RecF, RecO, and RecR proteins with RecA protein and single-stranded DNA binding protein Proceedings of the National Academy of Sciences of the United States of America. 90: 3875-3879. PMID 8483906  1
1993 Hall SD, Kane MF, Kolodner RD. Identification and characterization of the Escherichia coli RecT protein, a protein encoded by the recE region that promotes renaturation of homologous single-stranded DNA Journal of Bacteriology. 175: 277-287. PMID 8416902  1
1993 Heyer WD, Kolodner RD. Enzymology of homologous recombination in Saccharomyces cerevisiae Progress in Nucleic Acid Research and Molecular Biology. 46: 221-271. PMID 8234785  1
1992 Luisi-DeLuca C, Kolodner RD. Effect of terminal non-homology on intramolecular recombination of linear plasmid substrates in Escherichia coli Journal of Molecular Biology. 227: 72-80. PMID 1522602 DOI: 10.1016/0022-2836(92)90682-A  1
1992 Alani E, Thresher R, Griffith JD, Kolodner RD. Characterization of DNA-binding and strand-exchange stimulation properties of y-RPA, a yeast single-strand-DNA-binding protein Journal of Molecular Biology. 227: 54-71. PMID 1522601 DOI: 10.1016/0022-2836(92)90681-9  1
1992 Reenan RA, Kolodner RD. Isolation and characterization of two Saccharomyces cerevisiae genes encoding homologs of the bacterial HexA and MutS mismatch repair proteins. Genetics. 132: 963-73. PMID 1459447  1
1992 West AB, Roberts TM, Kolodner RD. Regulation of the reverse transcriptase of human immunodeficiency virus type 1 by dNTPs Proceedings of the National Academy of Sciences of the United States of America. 89: 9720-9724. PMID 1384060 DOI: 10.1073/pnas.89.20.9720  1
1992 Reenan RA, Kolodner RD. Characterization of insertion mutations in the Saccharomyces cerevisiae MSH1 and MSH2 genes: evidence for separate mitochondrial and nuclear functions. Genetics. 132: 975-85. PMID 1334021  1
1991 Lovett ST, Kolodner RD. Nucleotide sequence of the Escherichia coli recJ chromosomal region and construction of recJ-overexpression plasmids. Journal of Bacteriology. 173: 353-64. PMID 1987126  1
1991 Heyer WD, Johnson AW, Norris DN, Tishkoff D, Kolodner RD. Saccharomyces cerevisiae proteins involved in hybrid DNA formation in vitro Biochimie. 73: 269-276. PMID 1883885 DOI: 10.1016/0300-9084(91)90212-J  1
1991 Johnson AW, Kolodner RD. Strand exchange protein 1 from Saccharomyces cerevisiae: A novel multifunctional protein that contains DNA strand exchange and exonuclease activities Journal of Biological Chemistry. 266: 14046-14054. PMID 1856231  1
1991 Tishkoff DX, Johnson AW, Kolodner RD. Molecular and Genetic Analysis of the Gene Encoding the Saccharomyces cerevisiae Strand Exchange Protein Sep1 Molecular and Cellular Biology. 11: 2593-2608. PMID 1840632  1
1990 Griffin TJ, Kolodner RD. Purification and preliminary characterization of the Escherichia coli K-12 recF protein. Journal of Bacteriology. 172: 6291-9. PMID 2228960  1
1990 Heyer WD, Rao MR, Erdile LF, Kelly TJ, Kolodner RD. An essential Saccharomyces cerevisiae single-stranded DNA binding protein is homologous to the large subunit of human RP-A. The Embo Journal. 9: 2321-9. PMID 2192864  1
1989 Luisi-DeLuca C, Lovett ST, Kolodner RD. Genetic and physical analysis of plasmid recombination in recB recC sbcB and recB recC sbcA Escherichia coli K-12 mutants. Genetics. 122: 269-78. PMID 2670665  1
1989 Heyer WD, Kolodner RD. Purification and characterization of a protein from Saccharomyces cerevisiae that binds tightly to single-stranded DNA and stimulates a cognate strand exchange protein Biochemistry. 28: 2856-2862. PMID 2663063  1
1989 Lovett ST, Kolodner RD. Identification and purification of a single-stranded-DNA-specific exonuclease encoded by the recJ gene of Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America. 86: 2627-31. PMID 2649886  1
1989 Johnson RS, Sheng M, Greenberg ME, Kolodner RD, Papaioannou VE, Spiegelman BM. Targeting of nonexpressed genes in embryonic stem cells via homologous recombination. Science (New York, N.Y.). 245: 1234-6. PMID 2506639  1
1989 Bishop DK, Andersen J, Kolodner RD. Specificity of mismatch repair following transformation of Saccharomyces cerevisiae with heteroduplex plasmid DNA Proceedings of the National Academy of Sciences of the United States of America. 86: 3713-3717. PMID 2498874  1
1988 Luisi-DeLuca C, Clark AJ, Kolodner RD. Analysis of the recE locus of Escherichia coli K-12 by use of polyclonal antibodies to exonuclease VIII Journal of Bacteriology. 170: 5797-5805. PMID 3056915  1
1988 Smith CL, Kolodner RD. Mapping of Escherichia coli chromosomal Tn5 and F insertions by pulsed field gel electrophoresis Genetics. 119: 227-236. PMID 2840334  1
1975 Kolodner RD, Tewari KK. Chloroplast DNA from higher plants replicates by both the Cairns and the rolling circle mechanism. Nature. 256: 708-11. PMID 1153007  1
1975 Kolodner RD, Tewari KK. Denaturation mapping studies on the circular chloroplast deoxyribonucleic acid from pea leaves. The Journal of Biological Chemistry. 250: 4888-95. PMID 1150645  1
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