Nicholas Robin Waterfield - Publications

Affiliations: 
Warwick University (Medical School) 
Area:
Microbiology, pathogens, bacteria, toxins, genomics

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wang C, Chen M, Shao Y, Jiang M, Li Q, Chen L, Wu Y, Cen S, Waterfield NR, Yang J, Yang G. Genome wide analysis revealed conserved domains involved in the effector discrimination of bacterial type VI secretion system. Communications Biology. 6: 1195. PMID 38001377 DOI: 10.1038/s42003-023-05580-w  0.338
2021 Song N, Chen L, Zhou Z, Ren X, Liu B, Zhou S, Wang C, Wu Y, Waterfield NR, Yang J, Yang G. Genome-wide dissection reveals diverse pathogenic roles of bacterial Tc toxins. Plos Pathogens. 17: e1009102. PMID 33540421 DOI: 10.1371/journal.ppat.1009102  0.447
2021 Song N, Chen L, Ren X, Waterfield NR, Yang J, Yang G. N-Glycans and sulfated glycosaminoglycans contribute to the action of diverse Tc toxins on mammalian cells. Plos Pathogens. 17: e1009244. PMID 33539469 DOI: 10.1371/journal.ppat.1009244  0.351
2020 Hapeshi A, Healey JRJ, Mulley G, Waterfield NR. Temperature Restriction in Entomopathogenic Bacteria. Frontiers in Microbiology. 11: 548800. PMID 33101227 DOI: 10.3389/fmicb.2020.548800  0.317
2019 Simpson DH, Hapeshi A, Rogers NJ, Brabec V, Clarkson GJ, Fox DJ, Hrabina O, Kay GL, King AK, Malina J, Millard AD, Moat J, Roper DI, Song H, Waterfield NR, et al. Metallohelices that kill Gram-negative pathogens using intracellular antimicrobial peptide pathways. Chemical Science. 10: 9708-9720. PMID 32015803 DOI: 10.1039/c9sc03532j  0.3
2019 Chen L, Song N, Liu B, Zhang N, Alikhan NF, Zhou Z, Zhou Y, Zhou S, Zheng D, Chen M, Hapeshi A, Healey J, Waterfield NR, Yang J, Yang G. Genome-wide Identification and Characterization of a Superfamily of Bacterial Extracellular Contractile Injection Systems. Cell Reports. 29: 511-521.e2. PMID 31597107 DOI: 10.1016/j.celrep.2019.08.096  0.695
2019 Vlisidou I, Hapeshi A, Healey JR, Smart K, Yang G, Waterfield NR. The virulence cassettes deliver protein effectors directly into target eukaryotic cells. Elife. 8. PMID 31526474 DOI: 10.7554/eLife.46259  0.684
2019 Ffrench-Constant R, Waterfield N. An ABC Guide to the Bacterial Toxin Complexes. Advances in Applied Microbiology. 169-183. PMID 16543033 DOI: 10.1016/S0065-2164(05)58005-5  0.547
2018 Dorati F, Barrett GA, Sanchez-Contreras M, Arseneault T, José MS, Studholme DJ, Murillo J, Caballero P, Waterfield NR, Arnold DL, Shaw LJ, Jackson RW. Coping with Environmental Eukaryotes; Identification of Genes during the Interaction with Alternative Hosts or Predators. Microorganisms. 6. PMID 29690522 DOI: 10.3390/microorganisms6020032  0.327
2016 Jiang F, Wang X, Wang B, Chen L, Zhao Z, Waterfield NR, Yang G, Jin Q. The Pseudomonas aeruginosa Type VI Secretion PGAP1-like Effector Induces Host Autophagy by Activating Endoplasmic Reticulum Stress. Cell Reports. PMID 27477276 DOI: 10.1016/j.celrep.2016.07.012  0.37
2015 Mulley G, Beeton ML, Wilkinson P, Vlisidou I, Ockendon-Powell N, Hapeshi A, Tobias NJ, Nollmann FI, Bode HB, van den Elsen J, Ffrench-Constant RH, Waterfield NR. From Insect to Man: Photorhabdus Sheds Light on the Emergence of Human Pathogenicity. Plos One. 10: e0144937. PMID 26681201 DOI: 10.1371/Journal.Pone.0144937  0.57
2014 Jiang F, Waterfield NR, Yang J, Yang G, Jin Q. A Pseudomonas aeruginosa type VI secretion phospholipase D effector targets both prokaryotic and eukaryotic cells. Cell Host & Microbe. 15: 600-10. PMID 24832454 DOI: 10.1016/j.chom.2014.04.010  0.369
2013 Freeman ZN, Dorus S, Waterfield NR. The KdpD/KdpE two-component system: integrating K⁺ homeostasis and virulence. Plos Pathogens. 9: e1003201. PMID 23555240 DOI: 10.1371/journal.ppat.1003201  0.312
2012 Yang G, Hernández-Rodríguez CS, Beeton ML, Wilkinson P, Ffrench-Constant RH, Waterfield NR. Pdl1 is a putative lipase that enhances Photorhabdus toxin complex secretion. Plos Pathogens. 8: e1002692. PMID 22615559 DOI: 10.1371/Journal.Ppat.1002692  0.62
2012 Vlisidou I, Waterfield N, Wood W. Elucidating the in vivo targets of photorhabdus toxins in real-time using Drosophila embryos. Advances in Experimental Medicine and Biology. 710: 49-57. PMID 22127885 DOI: 10.1007/978-1-4419-5638-5_6  0.426
2010 Dowling AJ, Wilkinson PA, Holden MT, Quail MA, Bentley SD, Reger J, Waterfield NR, Titball RW, Ffrench-Constant RH. Genome-wide analysis reveals loci encoding anti-macrophage factors in the human pathogen Burkholderia pseudomallei K96243. Plos One. 5: e15693. PMID 21203527 DOI: 10.1371/Journal.Pone.0015693  0.594
2010 Vlisidou I, Eleftherianos I, Dorus S, Yang G, ffrench-Constant RH, Reynolds SE, Waterfield NR. The KdpD/KdpE two-component system of Photorhabdus asymbiotica promotes bacterial survival within M. sexta hemocytes. Journal of Invertebrate Pathology. 105: 352-62. PMID 20932844 DOI: 10.1016/J.Jip.2010.09.020  0.599
2010 Peat SM, Ffrench-Constant RH, Waterfield NR, Marokházi J, Fodor A, Adams BJ. A robust phylogenetic framework for the bacterial genus Photorhabdus and its use in studying the evolution and maintenance of bioluminescence: a case for 16S, gyrB, and glnA. Molecular Phylogenetics and Evolution. 57: 728-40. PMID 20732433 DOI: 10.1016/J.Ympev.2010.08.012  0.538
2010 Wilkinson P, Paszkiewicz K, Moorhouse A, Szubert JM, Beatson S, Gerrard J, Waterfield NR, Ffrench-Constant RH. New plasmids and putative virulence factors from the draft genome of an Australian clinical isolate of Photorhabdus asymbiotica. Fems Microbiology Letters. 309: 136-43. PMID 20584081 DOI: 10.1111/J.1574-6968.2010.02030.X  0.574
2010 Jones RT, Sanchez-Contreras M, Vlisidou I, Amos MR, Yang G, Muñoz-Berbel X, Upadhyay A, Potter UJ, Joyce SA, Ciche TA, Jenkins AT, Bagby S, Ffrench-Constant RH, Waterfield NR. Photorhabdus adhesion modification protein (Pam) binds extracellular polysaccharide and alters bacterial attachment. Bmc Microbiology. 10: 141. PMID 20462430 DOI: 10.1186/1471-2180-10-141  0.617
2009 Vlisidou I, Dowling AJ, Evans IR, Waterfield N, ffrench-Constant RH, Wood W. Drosophila embryos as model systems for monitoring bacterial infection in real time. Plos Pathogens. 5: e1000518. PMID 19609447 DOI: 10.1371/Journal.Ppat.1000518  0.61
2009 Wilkinson P, Waterfield NR, Crossman L, Corton C, Sanchez-Contreras M, Vlisidou I, Barron A, Bignell A, Clark L, Ormond D, Mayho M, Bason N, Smith F, Simmonds M, Churcher C, et al. Comparative genomics of the emerging human pathogen Photorhabdus asymbiotica with the insect pathogen Photorhabdus luminescens. Bmc Genomics. 10: 302. PMID 19583835 DOI: 10.1186/1471-2164-10-302  0.641
2009 Waterfield NR, Ciche T, Clarke D. Photorhabdus and a host of hosts. Annual Review of Microbiology. 63: 557-74. PMID 19575559 DOI: 10.1146/Annurev.Micro.091208.073507  0.386
2009 Ahantarig A, Chantawat N, Waterfield NR, ffrench-Constant R, Kittayapong P. PirAB toxin from Photorhabdus asymbiotica as a larvicide against dengue vectors. Applied and Environmental Microbiology. 75: 4627-9. PMID 19429564 DOI: 10.1128/Aem.00221-09  0.507
2009 Eleftherianos I, Waterfield NR, Bone P, Boundy S, ffrench-Constant RH, Reynolds SE. A single locus from the entomopathogenic bacterium Photorhabdus luminescens inhibits activated Manduca sexta phenoloxidase. Fems Microbiology Letters. 293: 170-6. PMID 19243439 DOI: 10.1111/J.1574-6968.2009.01523.X  0.64
2009 Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, Dorus S, Ffrench-Constant RH. Rapid Virulence Annotation (RVA): Identification of virulence factors using a bacterial genome library and multiple invertebrate hosts (Proceedings of the National Academy of Sciences of the United States of America (2008) 105, (15967-15972) DOI:10.1073/pnas.0711114105) Proceedings of the National Academy of Sciences of the United States of America. 106: 2083. DOI: 10.1073/Pnas.0811896106  0.549
2008 Waterfield NR, Sanchez-Contreras M, Eleftherianos I, Dowling A, Yang G, Wilkinson P, Parkhill J, Thomson N, Reynolds SE, Bode HB, Dorus S, Ffrench-Constant RH. Rapid Virulence Annotation (RVA): identification of virulence factors using a bacterial genome library and multiple invertebrate hosts. Proceedings of the National Academy of Sciences of the United States of America. 105: 15967-72. PMID 18838673 DOI: 10.1073/Pnas.0711114105  0.63
2007 Dowling AJ, Waterfield NR, Hares MC, Le Goff G, Streuli CH, ffrench-Constant RH. The Mcf1 toxin induces apoptosis via the mitochondrial pathway and apoptosis is attenuated by mutation of the BH3-like domain. Cellular Microbiology. 9: 2470-84. PMID 17848168 DOI: 10.1111/J.1462-5822.2007.00974.X  0.5
2007 Erickson DL, Waterfield NR, Vadyvaloo V, Long D, Fischer ER, Ffrench-Constant R, Hinnebusch BJ. Acute oral toxicity of Yersinia pseudotuberculosis to fleas: implications for the evolution of vector-borne transmission of plague. Cellular Microbiology. 9: 2658-66. PMID 17587333 DOI: 10.1111/j.1462-5822.2007.00986.x  0.449
2007 ffrench-Constant RH, Dowling A, Waterfield NR. Insecticidal toxins from Photorhabdus bacteria and their potential use in agriculture. Toxicon : Official Journal of the International Society On Toxinology. 49: 436-51. PMID 17207509 DOI: 10.1016/J.Toxicon.2006.11.019  0.595
2006 Gerrard JG, Joyce SA, Clarke DJ, ffrench-Constant RH, Nimmo GR, Looke DF, Feil EJ, Pearce L, Waterfield NR. Nematode symbiont for Photorhabdus asymbiotica. Emerging Infectious Diseases. 12: 1562-4. PMID 17176572 DOI: 10.3201/Eid1210.060464  0.554
2006 ffrench-Constant RH, Waterfield NR. Ground control for insect pests. Nature Biotechnology. 24: 660-1. PMID 16763595 DOI: 10.1038/Nbt0606-660  0.45
2006 Yang G, Dowling AJ, Gerike U, ffrench-Constant RH, Waterfield NR. Photorhabdus virulence cassettes confer injectable insecticidal activity against the wax moth. Journal of Bacteriology. 188: 2254-61. PMID 16513755 DOI: 10.1128/Jb.188.6.2254-2261.2006  0.6
2006 Ffrench-Constant R, Waterfield N. An ABC guide to the bacterial toxin complexes. Advances in Applied Microbiology. 58: 169-83. PMID 16509446  0.547
2005 Waterfield N, Kamita SG, Hammock BD, ffrench-Constant R. The Photorhabdus Pir toxins are similar to a developmentally regulated insect protein but show no juvenile hormone esterase activity. Fems Microbiology Letters. 245: 47-52. PMID 15796978 DOI: 10.1016/J.Femsle.2005.02.018  0.561
2004 Waterfield NR, Wren BW, Ffrench-Constant RH. Invertebrates as a source of emerging human pathogens. Nature Reviews. Microbiology. 2: 833-41. PMID 15378047 DOI: 10.1038/Nrmicro1008  0.605
2004 Gerrard J, Waterfield N, Vohra R, ffrench-Constant R. Human infection with Photorhabdus asymbiotica: an emerging bacterial pathogen. Microbes and Infection. 6: 229-237. PMID 15049334 DOI: 10.1016/J.Micinf.2003.10.018  0.55
2004 Dowling AJ, Daborn PJ, Waterfield NR, Wang P, Streuli CH, ffrench-Constant RH. The insecticidal toxin Makes caterpillars floppy (Mcf) promotes apoptosis in mammalian cells. Cellular Microbiology. 6: 345-53. PMID 15009026 DOI: 10.1046/J.1462-5822.2003.00357.X  0.518
2004 Waterfield NR, Daborn PJ, Ffrench-Constant RH. Insect pathogenicity islands in the insect pathogenic bacterium Photorhabdus Physiological Entomology. 29: 240-250. DOI: 10.1111/j.0307-6962.2004.00407.x  0.625
2003 Waterfield NR, Daborn PJ, Dowling AJ, Yang G, Hares M, ffrench-Constant RH. The insecticidal toxin makes caterpillars floppy 2 (Mcf2) shows similarity to HrmA, an avirulence protein from a plant pathogen. Fems Microbiology Letters. 229: 265-70. PMID 14680709 DOI: 10.1016/S0378-1097(03)00846-2  0.563
2003 Marokhazi J, Waterfield N, LeGoff G, Feil E, Stabler R, Hinds J, Fodor A, ffrench-Constant RH. Using a DNA microarray to investigate the distribution of insect virulence factors in strains of photorhabdus bacteria. Journal of Bacteriology. 185: 4648-56. PMID 12867479 DOI: 10.1128/Jb.185.15.4648-4656.2003  0.56
2003 ffrench-Constant R, Waterfield N, Daborn P, Joyce S, Bennett H, Au C, Dowling A, Boundy S, Reynolds S, Clarke D. Photorhabdus: towards a functional genomic analysis of a symbiont and pathogen. Fems Microbiology Reviews. 26: 433-56. PMID 12586390 DOI: 10.1111/J.1574-6976.2003.Tb00625.X  0.649
2002 Waterfield NR, Daborn PJ, ffrench-Constant RH. Genomic islands in Photorhabdus. Trends in Microbiology. 10: 541-5. PMID 12564983 DOI: 10.1016/S0966-842X(02)02463-0  0.609
2002 Sharma S, Waterfield N, Bowen D, Rocheleau T, Holland L, James R, ffrench-Constant R. The lumicins: novel bacteriocins from Photorhabdus luminescens with similarity to the uropathogenic-specific protein (USP) from uropathogenic Escherichia coli. Fems Microbiology Letters. 214: 241-9. PMID 12351238 DOI: 10.1111/J.1574-6968.2002.Tb11354.X  0.616
2002 Silva CP, Waterfield NR, Daborn PJ, Dean P, Chilver T, Au CP, Sharma S, Potter U, Reynolds SE, ffrench-Constant RH. Bacterial infection of a model insect: Photorhabdus luminescens and Manduca sexta. Cellular Microbiology. 4: 329-39. PMID 12067318 DOI: 10.1046/j.1462-5822.2002.00194.x  0.617
2001 Waterfield NR, Bowen DJ, Fetherston JD, Perry RD, ffrench-Constant RH. The tc genes of Photorhabdus: a growing family. Trends in Microbiology. 9: 185-91. PMID 11286884 DOI: 10.1016/S0966-842X(01)01978-3  0.551
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