Year |
Citation |
Score |
2023 |
Deshmukh PU, Lad SB, Sudarsan A, Sudhakar S, Aggarwal T, Mandal S, Bagale SS, Kondabagil K, Pradeepkumar PI. Human Translesion Synthesis Polymerases polκ and polη Perform Error-Free Replication across -dG Methyleugenol and Estragole DNA Adducts. Biochemistry. PMID 37486230 DOI: 10.1021/acs.biochem.2c00663 |
0.818 |
|
2023 |
Lad SB, Upadhyay M, Thorat P, Nair D, Moseley GW, Srivastava S, Pradeepkumar PI, Kondabagil K. Biochemical reconstitution of the mimiviral base excision repair pathway. Journal of Molecular Biology. 168188. PMID 37380013 DOI: 10.1016/j.jmb.2023.168188 |
0.408 |
|
2022 |
Boldinova EO, Ghodke PP, Sudhakar S, Mishra VK, Manukyan AA, Miropolskaya N, Pradeepkumar PI, Makarova AV. Translesion Synthesis across the -Ethyl-deoxyguanosine Adduct by Human PrimPol. Acs Chemical Biology. PMID 36318733 DOI: 10.1021/acschembio.2c00717 |
0.823 |
|
2022 |
Kumar S, Pany SPP, Sudhakar S, Singh SB, Todankar CS, Pradeepkumar PI. Targeting Parallel Topology of G-Quadruplex Structures by Indole- Fused Quindoline Scaffolds. Biochemistry. PMID 36314731 DOI: 10.1021/acs.biochem.2c00373 |
0.754 |
|
2022 |
Kumar S, Reddy Sannapureddi RK, Todankar CS, Ramanathan R, Biswas A, Sathyamoorthy B, Pradeepkumar PI. Bisindolylmaleimide Ligands Stabilize G-Quadruplex DNA Structure and Downregulate Gene Expression. Biochemistry. PMID 35584037 DOI: 10.1021/acs.biochem.2c00116 |
0.801 |
|
2022 |
Biswas A, Singh SB, Todankar CS, Sudhakar S, Pany SPP, Pradeepkumar PI. Stabilization and fluorescence light-up of G-quadruplex nucleic acids using indolyl-quinolinium based probes. Physical Chemistry Chemical Physics : Pccp. 24: 6238-6255. PMID 35229834 DOI: 10.1039/d1cp04718c |
0.651 |
|
2022 |
Jana SK, Harikrishna S, Sudhakar S, El-Khoury R, Pradeepkumar PI, Damha MJ. Nucleoside Analogues with a Seven-Membered Sugar Ring: Synthesis and Structural Compatibility in DNA-RNA Hybrids. The Journal of Organic Chemistry. 87: 2367-2379. PMID 35133166 DOI: 10.1021/acs.joc.1c02254 |
0.81 |
|
2020 |
Habibian M, Harikrishna S, Fakhoury J, Barton M, Ageely EA, Cencic R, Fakih HH, Katolik A, Takahashi M, Rossi J, Pelletier J, Gagnon KT, Pradeepkumar PI, Damha MJ. Effect of 2'-5'/3'-5' phosphodiester linkage heterogeneity on RNA interference. Nucleic Acids Research. PMID 32282904 DOI: 10.1093/Nar/Gkaa222 |
0.75 |
|
2020 |
Ghodke PP, Pradeepkumar PI. Site‐Specific N2‐dG DNA Adducts: Formation, Synthesis, and TLS Polymerase‐Mediated Bypass European Journal of Organic Chemistry. DOI: 10.1002/Ejoc.202000298 |
0.829 |
|
2019 |
Dhamodharan V, Pradeepkumar PI. Specific Recognition of Promoter G-Quadruplex DNAs by Small Molecule Ligands and Light-up Probes. Acs Chemical Biology. 14: 2102-2114. PMID 31532996 DOI: 10.1021/Acschembio.9B00475 |
0.427 |
|
2019 |
Ghodke PP, Pradeepkumar PI. Synthesis of N -Aryl-2'-Deoxyguanosine Modified Phosphoramidites and Oligonucleotides. Current Protocols in Nucleic Acid Chemistry. 78: e93. PMID 31529784 DOI: 10.1002/Cpnc.93 |
0.819 |
|
2019 |
Pani SPP, Mahak S, Sharma J, Venugopal D, Patankar S, Pradeepkumar PI. Presence of potential G-quadruplex RNA forming motifs at the 5'-UTR of PP2Acα mRNA repress translation. Chembiochem : a European Journal of Chemical Biology. PMID 31206965 DOI: 10.1002/Cbic.201900336 |
0.356 |
|
2019 |
Gupta A, Lad SB, Ghodke PP, Pradeepkumar PI, Kondabagil K. Mimivirus encodes a multifunctional primase with DNA/RNA polymerase, terminal transferase and translesion synthesis activities. Nucleic Acids Research. PMID 31001622 DOI: 10.1093/Nar/Gkz236 |
0.818 |
|
2019 |
Ghodke PP, Bommisetti P, Nair DT, Pradeepkumar PI. Synthesis of N-Deoxyguanosine Modified DNAs and the Studies on Their Translesion Synthesis by the E. coli DNA Polymerase IV. The Journal of Organic Chemistry. 84: 1734-1747. PMID 30628447 DOI: 10.1021/Acs.Joc.8B02082 |
0.83 |
|
2019 |
Kumari B, Yadav A, Pany SP, Pradeepkumar PI, Kanvah S. Cationic red emitting fluorophore: A light up NIR fluorescent probe for G4-DNA. Journal of Photochemistry and Photobiology. B, Biology. 190: 128-136. PMID 30529810 DOI: 10.1016/J.Jphotobiol.2018.10.007 |
0.56 |
|
2017 |
Anas M, Sharma R, Dhamodharan V, Pradeepkumar PI, Manhas A, Srivastava K, Ahmed S, Kumar N. Investigating Pharmacological Targeting of G-Quadruplexes in the Human Malaria Parasite. Biochemistry. PMID 29182860 DOI: 10.1021/Acs.Biochem.7B00964 |
0.358 |
|
2017 |
Yockey O, Jha V, Ghodke PP, Xu T, Xu W, Ling H, Pradeepkumar PI, Zhao L. Mechanism of Error-Free DNA Replication Past Lucidin-Derived DNA Damage by Human DNA Polymerase κ. Chemical Research in Toxicology. PMID 28972744 DOI: 10.1021/Acs.Chemrestox.7B00227 |
0.842 |
|
2017 |
Harikrishna S, Kotaru S, Pradeepkumar PI. Ligand-induced conformational preorganization of loops of c-MYC G-quadruplex DNA and its implications in structure-specific drug design. Molecular Biosystems. 13: 1458-1468. PMID 28650023 DOI: 10.1039/C7Mb00175D |
0.777 |
|
2017 |
Harikrishna S, Pradeepkumar PI. Probing the Binding Interactions between Chemically Modified siRNAs and Human Argonaute 2 Using Microsecond Molecular Dynamics Simulations. Journal of Chemical Information and Modeling. 57: 883-896. PMID 28287733 DOI: 10.1021/Acs.Jcim.6B00773 |
0.749 |
|
2017 |
Malhotra R, Rarhi C, Diveshkumar KV, Bommisetti P, Pany SPP, Roy S, Pradeepkumar PI, Kundu M. Pyridopyrimidinone Derivatives as DNAG-Quadruplex-Stabilizing Agents: Design, Synthesis and Biophysical Studies Chemistryselect. 2: 5206-5213. DOI: 10.1002/SLCT.201700677 |
0.77 |
|
2016 |
Malhotra R, Rarhi C, Diveshkumar KV, Barik R, D'cunha R, Dhar P, Kundu M, Chattopadhyay S, Roy S, Basu S, Pradeepkumar PI, Hajra S. Dihydrochelerythrine and its derivatives: Synthesis and their application as potential G-quadruplex DNA stabilizing agents. Bioorganic & Medicinal Chemistry. PMID 27234888 DOI: 10.1016/J.Bmc.2016.04.059 |
0.789 |
|
2016 |
Diveshkumar KV, Sakrikar S, Rosu F, Harikrishna S, Gabelica V, Pradeepkumar PI. Specific Stabilization of c-MYC and c-KIT G -Quadruplex DNA Structures by Indolylmethyleneindanone Scaffolds. Biochemistry. PMID 27226253 DOI: 10.1021/Acs.Biochem.6B00120 |
0.828 |
|
2016 |
Pany SP, Bommisetti P, Diveshkumar KV, Pradeepkumar PI. Benzothiazole hydrazones of furylbenzamides preferentially stabilize c-MYC and c-KIT1 promoter G-quadruplex DNAs. Organic & Biomolecular Chemistry. 14: 5779-93. PMID 27021281 DOI: 10.1039/C6Ob00138F |
0.846 |
|
2015 |
Ghodke PP, Gore KR, Harikrishna S, Samanta B, Kottur J, Nair DT, Pradeepkumar PI. The N2-Furfuryl-Deoxyguanosine (fdG) Adduct Does Not Alter the Structure of B-DNA. The Journal of Organic Chemistry. PMID 26650891 DOI: 10.1021/Acs.Joc.5B02341 |
0.822 |
|
2015 |
Kota S, Dhamodharan V, Pradeepkumar PI, Misra HS. G-quadruplex forming structural motifs in the genome of Deinococcus radiodurans and their regulatory roles in promoter functions. Applied Microbiology and Biotechnology. PMID 26201493 DOI: 10.1007/S00253-015-6808-6 |
0.447 |
|
2015 |
Ghodke PP, Harikrishna S, Pradeepkumar PI. Synthesis and polymerase-mediated bypass studies of the N2-deoxyguanosine DNA damage caused by a lucidin analogue. The Journal of Organic Chemistry. 80: 2128-38. PMID 25574682 DOI: 10.1021/Jo502627B |
0.843 |
|
2015 |
Kottur J, Sharma A, Gore KR, Narayanan N, Samanta B, Pradeepkumar PI, Nair DT. Unique structural features in DNA polymerase IV enable efficient bypass of the N2 adduct induced by the nitrofurazone antibiotic. Structure (London, England : 1993). 23: 56-67. PMID 25497730 DOI: 10.1016/J.Str.2014.10.019 |
0.816 |
|
2015 |
Dhamodharan V, Harikrishna S, Bhasikuttan AC, Pradeepkumar PI. Topology specific stabilization of promoter over telomeric G-quadruplex DNAs by bisbenzimidazole carboxamide derivatives. Acs Chemical Biology. 10: 821-33. PMID 25495750 DOI: 10.1021/Cb5008597 |
0.813 |
|
2014 |
Diveshkumar KV, Sakrikar S, Harikrishna S, Dhamodharan V, Pradeepkumar PI. Targeting promoter G-quadruplex DNAs by indenopyrimidine-based ligands. Chemmedchem. 9: 2754-65. PMID 25359695 DOI: 10.1002/Cmdc.201402394 |
0.825 |
|
2014 |
Biswas A, Swarnkar RK, Hussain B, Sahoo SK, Pradeepkumar PI, Patwari GN, Anand R. Fluorescence quenching studies of γ-butyrolactone binding protein (CprB) from Streptomyces coelicolor A3(2). The Journal of Physical Chemistry. B. 118: 10035-42. PMID 25075976 DOI: 10.1021/Jp503589H |
0.545 |
|
2014 |
Gracie K, Dhamodharan V, Pradeepkumar PI, Faulds K, Graham D. Qualitative SERS analysis of G-quadruplex DNAs using selective stabilising ligands. The Analyst. 139: 4458-65. PMID 24821331 DOI: 10.1039/C4An00551A |
0.508 |
|
2013 |
Gore KR, Harikrishna S, Pradeepkumar PI. Influence of 2'-fluoro versus 2'-O-methyl substituent on the sugar puckering of 4'-C-aminomethyluridine. The Journal of Organic Chemistry. 78: 9956-62. PMID 24016294 DOI: 10.1021/Jo4012333 |
0.775 |
|
2013 |
Kumar V, Gore KR, Pradeepkumar PI, Kesavan V. Design, synthesis, biophysical and primer extension studies of novel acyclic butyl nucleic acid (BuNA). Organic & Biomolecular Chemistry. 11: 5853-65. PMID 23903805 DOI: 10.1039/C3Ob41244J |
0.831 |
|
2013 |
Mohanty J, Barooah N, Dhamodharan V, Harikrishna S, Pradeepkumar PI, Bhasikuttan AC. Thioflavin T as an efficient inducer and selective fluorescent sensor for the human telomeric G-quadruplex DNA. Journal of the American Chemical Society. 135: 367-76. PMID 23215453 DOI: 10.1021/Ja309588H |
0.789 |
|
2012 |
Nawale GN, Gore KR, Höbartner C, Pradeepkumar PI. Incorporation of 4'-C-aminomethyl-2'-O-methylthymidine into DNA by thermophilic DNA polymerases. Chemical Communications (Cambridge, England). 48: 9619-21. PMID 22908130 DOI: 10.1039/C2Cc35222B |
0.829 |
|
2012 |
Gore KR, Nawale GN, Harikrishna S, Chittoor VG, Pandey SK, Höbartner C, Patankar S, Pradeepkumar PI. Synthesis, gene silencing, and molecular modeling studies of 4'-C-aminomethyl-2'-O-methyl modified small interfering RNAs. The Journal of Organic Chemistry. 77: 3233-45. PMID 22372696 DOI: 10.1021/Jo202666M |
0.778 |
|
2012 |
Dhamodharan V, Harikrishna S, Jagadeeswaran C, Halder K, Pradeepkumar PI. Selective G-quadruplex DNA stabilizing agents based on bisquinolinium and bispyridinium derivatives of 1,8-naphthyridine. The Journal of Organic Chemistry. 77: 229-42. PMID 22126189 DOI: 10.1021/Jo201816G |
0.835 |
|
2011 |
Wong OY, Pradeepkumar PI, Silverman SK. DNA-catalyzed covalent modification of amino acid side chains in tethered and free peptide substrates. Biochemistry. 50: 4741-9. PMID 21510668 DOI: 10.1021/Bi200585N |
0.793 |
|
2011 |
Dhamodharan V, Harikrishna S, Jagadeeswaran C, Pradeepkumar PI. G-Quadruplex DNA stabilizing agents based on 1,8-naphthyridine Collection of Czechoslovak Chemical Communications. 12: 433-434. DOI: 10.1135/Css201112433 |
0.803 |
|
2010 |
Shukla S, Sumaria CS, Pradeepkumar PI. Exploring chemical modifications for siRNA therapeutics: a structural and functional outlook. Chemmedchem. 5: 328-49. PMID 20043313 DOI: 10.1002/Cmdc.200900444 |
0.377 |
|
2008 |
Kost DM, Gerdt JP, Pradeepkumar PI, Silverman SK. Controlling the direction of site-selectivity and regioselectivity in RNA ligation by Zn2+-dependent deoxyribozymes that use 2',3'-cyclic phosphate RNA substrates. Organic & Biomolecular Chemistry. 6: 4391-8. PMID 19005599 DOI: 10.1039/B813566E |
0.602 |
|
2008 |
Pradeepkumar PI, Höbartner C, Baum DA, Silverman SK. DNA-catalyzed formation of nucleopeptide linkages. Angewandte Chemie (International Ed. in English). 47: 1753-7. PMID 18214866 DOI: 10.1002/Anie.200703676 |
0.806 |
|
2007 |
Höbartner C, Pradeepkumar PI, Silverman SK. Site-selective depurination by a periodate-dependent deoxyribozyme. Chemical Communications (Cambridge, England). 2255-7. PMID 17534508 DOI: 10.1039/B704507G |
0.547 |
|
2005 |
Isaksson J, Plashkevych O, Pradeepkumar PI, Chatterjee S, Barman J, Pathmasiri W, Shrivastava P, Petit C, Chattopadhyaya J. Oxetane locked thymidine in the Dickerson-Drew dodecamer causes local base pairing distortions -- an NMR structure and hydration study. Journal of Biomolecular Structure & Dynamics. 23: 299-330. PMID 16218756 DOI: 10.1080/07391102.2005.10507067 |
0.515 |
|
2004 |
Opalinska JB, Kalota A, Gifford LK, Lu P, Jen KY, Pradeepkumar PI, Barman J, Kim TK, Swider CR, Chattopadhyaya J, Gewirtz AM. Oxetane modified, conformationally constrained, antisense oligodeoxyribonucleotides function efficiently as gene silencing molecules. Nucleic Acids Research. 32: 5791-9. PMID 15514112 DOI: 10.1093/Nar/Gkh893 |
0.537 |
|
2004 |
Pradeepkumar PI, Cheruku P, Plashkevych O, Acharya P, Gohil S, Chattopadhyaya J. Synthesis, physicochemical and biochemical studies of 1',2'-oxetane constrained adenosine and guanosine modified oligonucleotides, and their comparison with those of the corresponding cytidine and thymidine analogues. Journal of the American Chemical Society. 126: 11484-99. PMID 15366894 DOI: 10.1021/Ja048417I |
0.576 |
|
2003 |
Pradeepkumar PI, Amirkhanov NV, Chattopadhyaya J. Antisense oligonuclotides with oxetane-constrained cytidine enhance heteroduplex stability, and elicit satisfactory RNase H response as well as showing improved resistance to both exo and endonucleases. Organic & Biomolecular Chemistry. 1: 81-92. PMID 12929393 DOI: 10.1039/B210163G |
0.575 |
|
2002 |
Boon EM, Barton JK, Pradeepkumar PI, Isaksson J, Petit C, Chattopadhyaya J. An electrochemical probe of DNA stacking in an antisense oligonucleotide containing a C3'-endo-locked sugar. Angewandte Chemie (International Ed. in English). 41: 3402-5. PMID 12298045 DOI: 10.1002/1521-3773(20020916)41:18<3402::Aid-Anie3402>3.0.Co;2-6 |
0.694 |
|
2002 |
Acharya P, Issakson J, Pradeepkumar PI, Chattopadhyaya J. Experimental Evidences Unequivocally Prove The Role Of Stereoelectronics As One Of The Major Forces Responsible For The Self-Assembly Of Dna And Rna Collection of Czechoslovak Chemical Communications. 5: 99-120. DOI: 10.1135/Css200205099 |
0.58 |
|
2002 |
Amirkhanov NV, Pradeepkumar PI, Chattopadhyaya J. Kinetic analysis of the RNA cleavage of the conformationally-constrained oxetane-modified antisense-RNA hybrid duplex by RNase H Journal of the Chemical Society-Perkin Transactions 1. 976-984. DOI: 10.1039/B111438G |
0.515 |
|
2001 |
Ossipov D, Pradeepkumar PI, Holmer M, Chattopadhyaya J. Synthesis of [Ru(phen)(2)dppz](2+)-tethered oligo-DNA and studies on the metallointercalation mode into the DNA duplex. Journal of the American Chemical Society. 123: 3551-62. PMID 11472126 DOI: 10.1021/Ja003985T |
0.693 |
|
2001 |
Zamaratski E, Pradeepkumar PI, Chattopadhyaya J. A critical survey of the structure-function of the antisense oligo/RNA heteroduplex as substrate for RNase H. Journal of Biochemical and Biophysical Methods. 48: 189-208. PMID 11384757 DOI: 10.1016/S0165-022X(01)00149-X |
0.559 |
|
2001 |
Pradeepkumar PI, Chattopadhyaya J. Oxetane modified antisense oligonucleotides promote RNase H cleavage of the complementary RNA strand in the hybrid duplex as efficiently as the native, and offer improved endonuclease resistance Journal of the Chemical Society-Perkin Transactions 1. 2074-2083. DOI: 10.1039/B106281F |
0.567 |
|
2001 |
Pradeepkumar PI, Zamaratski E, Foldesi A, Chattopadhyaya J. Conformation-specific cleavage of antisense oligonucleotide-RNA duplexes by RNase H Journal of the Chemical Society-Perkin Transactions 1. 402-408. DOI: 10.1039/B006476I |
0.576 |
|
2001 |
Zamaratski E, Ossipov D, Pradeepkumar PI, Amirkhanov N, Chattopadhyaya J. The 3′-modified antisense oligos promote faster hydrolysis of the target RNA by RNase H than the natural counterpart Tetrahedron. 57: 593-606. DOI: 10.1016/S0040-4020(00)01029-2 |
0.553 |
|
2000 |
Pradeepkumar PI, Zamaratski E, Foldesi A, Chattopadhyaya J. Transmission of the conformational information in the antisense:RNA hybrid duplex influences the pattern of the RNase H cleavage reaction † Tetrahedron Letters. 41: 8601-8607. DOI: 10.1016/S0040-4039(00)01510-0 |
0.528 |
|
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