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Brian M. Paegel, Ph.D. - Publications

Affiliations: 
2009-2019 Chemistry Scripps Research Institute, La Jolla, La Jolla, CA, United States 
 2019- Pharmaceutical Sciences University of California, Irvine, Irvine, CA 
Area:
multi-phase chemistry, molecular combinatorics, instrumentation engineering, drug discovery
Website:
https://faculty.sites.uci.edu/paegel/
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Cavett V, Paegel BM. Multiplexed Enzyme Activity-Based Probe Display via Hybridization Acs Combinatorial Science. PMID 32803953 DOI: 10.1021/Acscombsci.0C00116  0.389
2019 Hackler A, FitzGerald FG, Dang VQ, Satz AL, Paegel BM. Off-DNA DNA-Encoded Library Affinity Screening. Acs Combinatorial Science. PMID 31829554 DOI: 10.1021/Acscombsci.9B00153  0.793
2019 Ratnayake AS, Flanagan ME, Foley TL, Smith JD, Johnson JG, Bellenger J, Montgomery JI, Paegel BM. A Solution Phase Platform to Characterize Chemical Reaction Compatibility with DNA-Encoded Chemical Library Synthesis. Acs Combinatorial Science. PMID 31425646 DOI: 10.1021/Acscombsci.9B00113  0.406
2019 Vallejo D, Nikoomanzar A, Paegel BM, Chaput JC. Fluorescence-Activated Droplet Sorting for Single-Cell Directed Evolution. Acs Synthetic Biology. PMID 31120731 DOI: 10.1021/Acssynbio.9B00103  0.306
2019 Cochrane W, Malone ML, Dang VQ, Cavett VJ, Satz AL, Paegel BM. Activity-Based DNA-Encoded Library Screening. Acs Combinatorial Science. PMID 30884226 DOI: 10.1021/Acscombsci.9B00037  0.784
2017 Cochrane W, Hackler AL, Cavett VJ, Price AK, Paegel BM. Integrated, Continuous Emulsion Creamer. Analytical Chemistry. PMID 29124927 DOI: 10.1021/Acs.Analchem.7B03070  0.753
2017 MacConnell AB, Paegel BM. The Poisson Statistics of Combinatorial Library Sampling Predict False Discovery Rates of Screening. Acs Combinatorial Science. PMID 28682059 DOI: 10.1021/Acscombsci.7B00061  0.788
2017 MacConnell AB, Price AK, Paegel BM. An Integrated Microfluidic Processor for DNA-Encoded Combinatorial Library Functional Screening. Acs Combinatorial Science. PMID 28199790 DOI: 10.1021/Acscombsci.6B00192  0.816
2017 Malone ML, Cavett VJ, Paegel BM. Chemoselective Coupling Preserves the Substrate Integrity of Surface-Immobilized Oligonucleotides for Emulsion PCR-Based Gene Library Construction. Acs Combinatorial Science. 19: 9-14. PMID 28064476 DOI: 10.1021/Acscombsci.6B00146  0.763
2016 Mendes KR, Malone ML, Ndungu JM, Suponitsky-Kroyter I, Cavett VJ, McEnaney PJ, MacConnell AB, Doran TM, Ronacher K, Stanley K, Utset O, Walzl G, Paegel BM, Kodadek T. High-throughput Identification of DNA-Encoded IgG Ligands that Distinguish Active and Latent Mycobacterium tuberculosis Infections. Acs Chemical Biology. PMID 27957856 DOI: 10.1021/Acschembio.6B00855  0.761
2016 Malone ML, Paegel BM. What is a "DNA-Compatible" Reaction? Acs Combinatorial Science. PMID 26971959 DOI: 10.1021/Acscombsci.5B00198  0.746
2016 Price AK, MacConnell AB, Paegel BM. hνSABR: Photochemical Dose-Response Bead Screening in Droplets. Analytical Chemistry. PMID 26815064 DOI: 10.1021/Acs.Analchem.5B04811  0.788
2015 Price AK, Paegel BM. Discovery in Droplets. Analytical Chemistry. PMID 26558892 DOI: 10.1021/Acs.Analchem.5B04139  0.427
2015 MacConnell AB, McEnaney PJ, Cavett VJ, Paegel BM. DNA-Encoded Solid-Phase Synthesis: Encoding Language Design and Complex Oligomer Library Synthesis. Acs Combinatorial Science. 17: 518-34. PMID 26290177 DOI: 10.1021/Acscombsci.5B00106  0.791
2014 Price AK, MacConnell AB, Paegel BM. Microfluidic bead suspension hopper. Analytical Chemistry. 86: 5039-44. PMID 24761972 DOI: 10.1021/Ac500693R  0.801
2011 Matosevic S, Paegel BM. Stepwise synthesis of giant unilamellar vesicles on a microfluidic assembly line. Journal of the American Chemical Society. 133: 2798-800. PMID 21309555 DOI: 10.1021/Ja109137S  0.305
2010 Paegel BM, Joyce GF. Microfluidic compartmentalized directed evolution. Chemistry & Biology. 17: 717-24. PMID 20659684 DOI: 10.1016/J.Chembiol.2010.05.021  0.564
2008 Paegel BM, Joyce GF. Darwinian evolution on a chip. Plos Biology. 6: e85. PMID 18399721 DOI: 10.1371/Journal.Pbio.0060085  0.54
2008 Paegel BM, Joyce GF. Microfluidic darwinian evolution 12th International Conference On Miniaturized Systems For Chemistry and Life Sciences - the Proceedings of Microtas 2008 Conference. 637-639.  0.478
2006 Paegel BM, Grover WH, Skelley AM, Mathies RA, Joyce GF. Microfluidic serial dilution circuit. Analytical Chemistry. 78: 7522-7. PMID 17073422 DOI: 10.1021/Ac0608265  0.753
2005 Paegel BM, Joyce GF. Microfluidic serial transfer circuit: Automated evolution of RNA catalysts Micro Total Analysis Systems - Proceedings of Microtas 2005 Conference: 9th International Conference On Miniaturized Systems For Chemistry and Life Sciences. 1: 28-30.  0.452
2004 Doherty EA, Kan CW, Paegel BM, Yeung SH, Cao S, Mathies RA, Barron AE. Sparsely cross-linked "nanogel" matrixes as fluid, mechanically stabilized polymer networks for high-throughput microchannel DNA sequencing. Analytical Chemistry. 76: 5249-56. PMID 15362880 DOI: 10.1021/Ac049721X  0.535
2004 Kamei T, Paegel BM, Scherer JR, Skelley AM, Street RA, Mathies RA. Fusion of a-Si:H sensor technology with microfluidic bioanalytical devices Journal of Non-Crystalline Solids. 338: 715-719. DOI: 10.1016/J.Jnoncrysol.2004.03.117  0.754
2003 Kamei T, Paegel BM, Scherer JR, Skelley AM, Street RA, Mathies RA. Integrated hydrogenated amorphous Si photodiode detector for microfluidic bioanalytical devices. Analytical Chemistry. 75: 5300-5. PMID 14710806 DOI: 10.1021/Ac0301550  0.762
2003 Blazej RG, Paegel BM, Mathies RA. Polymorphism ratio sequencing: a new approach for single nucleotide polymorphism discovery and genotyping. Genome Research. 13: 287-93. PMID 12566407 DOI: 10.1101/Gr.396203  0.558
2003 Paegel BM, Blazej RG, Mathies RA. Microfluidic devices for DNA sequencing: sample preparation and electrophoretic analysis. Current Opinion in Biotechnology. 14: 42-50. PMID 12566001 DOI: 10.1016/S0958-1669(02)00004-6  0.588
2003 Kamei T, Paegel BM, Lagally ET, Skelley AM, Scherer JR, Street RA, Mathies RA. Development of an integrated a-Si:H photodiode detector and its evaluation for chemical and biochemical microfluidic analysis The Japan Society of Applied Physics. DOI: 10.7567/Ssdm.2003.F-6-1  0.496
2003 Blazej RG, Paegel BM, Emrich CA, Mathies RA. Microfabricated capillary array electrophoresis. Implementation and applications. Lab-On-a-Chip: Miniaturized Systems For (Bio) Chemical Analysis and Synthesis. 231-247. DOI: 10.1016/B978-044451100-3/50012-7  0.761
2003 Kamei T, Scherer JR, Paegel BM, Lagally ET, Skelley AM, Street RA, Mathies RA. Microfluidic Genetic and Amino Acid Analysis using an Integrated a-Si:H Detector Proceedings of Ieee Sensors. 2: 1049-1053.  0.717
2002 Paegel BM, Yeung SH, Mathies RA. Microchip bioprocessor for integrated nanovolume sample purification and DNA sequencing. Analytical Chemistry. 74: 5092-8. PMID 12380835 DOI: 10.1021/Ac0203645  0.568
2002 Paegel BM, Emrich CA, Wedemayer GJ, Scherer JR, Mathies RA. High throughput DNA sequencing with a microfabricated 96-lane capillary array electrophoresis bioprocessor. Proceedings of the National Academy of Sciences of the United States of America. 99: 574-9. PMID 11792836 DOI: 10.1073/Pnas.012608699  0.802
2001 Scherer JR, Paegel BM, Wedemayer GJ, Emrich CA, Lo J, Medintz IL, Mathies RA. High-pressure gel loader for capillary array electrophoresis microchannel plates. Biotechniques. 31: 1150-2, 1154. PMID 11730021 DOI: 10.2144/01315Rr04  0.767
2001 Medintz IL, Paegel BM, Blazej RG, Emrich CA, Berti L, Scherer JR, Mathies RA. High-performance genetic analysis using microfabricated capillary array electrophoresis microplates. Electrophoresis. 22: 3845-56. PMID 11700713 DOI: 10.1002/1522-2683(200110)22:18<3845::Aid-Elps3845>3.0.Co;2-0  0.798
2001 Medintz IL, Paegel BM, Mathies RA. Microfabricated capillary array electrophoresis DNA analysis systems. Journal of Chromatography. A. 924: 265-70. PMID 11521873 DOI: 10.1016/S0021-9673(01)00852-4  0.599
2000 Paegel BM, Hutt LD, Simpson PC, Mathies RA. Turn geometry for minimizing band broadening in microfabricated capillary electrophoresis channels. Analytical Chemistry. 72: 3030-7. PMID 10939363 DOI: 10.1021/Ac000054R  0.467
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