Year |
Citation |
Score |
2019 |
Kim BH, Wang FI, Pereverzev A, Chidiac P, Dixon SJ. Toward Defining the Pharmacophore for Positive Allosteric Modulation of PTH1 Receptor Signaling by Extracellular Nucleotides. Acs Pharmacology & Translational Science. 2: 155-167. PMID 32259054 DOI: 10.1021/acsptsci.8b00053 |
0.321 |
|
2019 |
Thibeault PE, LeSarge JC, Arends D, Fernandes M, Chidiac P, Stathopulos PB, Luyt LG, Ramachandran R. Molecular basis for activation and biased signalling at the thrombin-activated GPCR Proteinase Activated Receptor-4 (PAR4). The Journal of Biological Chemistry. PMID 31892516 DOI: 10.1074/Jbc.Ra119.011461 |
0.405 |
|
2019 |
Wang CH, Chidiac P. RGS2 promotes the translation of stress-associated proteins ATF4 and CHOP via its eIF2B-inhibitory domain. Cellular Signalling. PMID 30826455 DOI: 10.1016/J.Cellsig.2019.02.007 |
0.336 |
|
2018 |
Kim BH, Pereverzev A, Zhu S, Tong AOM, Jeffrey Dixon S, Chidiac P. Extracellular nucleotides enhance agonist potency at the parathyroid hormone 1 receptor. Cellular Signalling. PMID 29501726 DOI: 10.1016/J.Cellsig.2018.02.015 |
0.471 |
|
2017 |
Lee KN, Lu X, Nguyen C, Feng Q, Chidiac P. Cardiomyocyte specific overexpression of a 37 amino acid domain of regulator of G protein signalling 2 inhibits cardiac hypertrophy and improves function in response to pressure overload in mice. Journal of Molecular and Cellular Cardiology. PMID 28641980 DOI: 10.1016/J.Yjmcc.2017.06.007 |
0.361 |
|
2016 |
Narla C, Scidmore T, Jeong J, Everest M, Chidiac P, Poulter MO. A switch in G protein coupling for type 1 corticotropin-releasing factor receptors promotes excitability in epileptic brains. Science Signaling. 9: ra60. PMID 27303056 DOI: 10.1126/Scisignal.Aad8676 |
0.403 |
|
2016 |
Chidiac P. RGS proteins destroy spare receptors: Effects of GPCR-interacting proteins and signal deamplification on measurements of GPCR agonist potency. Methods (San Diego, Calif.). 92: 87-93. PMID 26297537 DOI: 10.1016/J.Ymeth.2015.08.011 |
0.534 |
|
2015 |
Chidiac P, Hébert TE. GPCR Retreat 2014: a good view leads to many discoveries! Journal of Receptor and Signal Transduction Research. 35: 208-12. PMID 26366680 DOI: 10.3109/10799893.2015.1072977 |
0.395 |
|
2015 |
Zhao P, Chidiac P. Regulation of RGS5 GAP activity by GPSM3. Molecular and Cellular Biochemistry. 405: 33-40. PMID 25842189 DOI: 10.1007/S11010-015-2393-3 |
0.49 |
|
2014 |
Thompson MD, Cole DE, Jose PA, Chidiac P. G protein-coupled receptor accessory proteins and signaling: pharmacogenomic insights. Methods in Molecular Biology (Clifton, N.J.). 1175: 121-52. PMID 25150869 DOI: 10.1007/978-1-4939-0956-8_7 |
0.534 |
|
2014 |
Chidiac P, Sobiesiak AJ, Lee KN, Gros R, Nguyen CH. The eIF2B-interacting domain of RGS2 protects against GPCR agonist-induced hypertrophy in neonatal rat cardiomyocytes. Cellular Signalling. 26: 1226-34. PMID 24576550 DOI: 10.1016/J.Cellsig.2014.02.006 |
0.451 |
|
2013 |
Zhao P, Cladman W, Van Tol HH, Chidiac P. Fine-tuning of GPCR signals by intracellular G protein modulators. Progress in Molecular Biology and Translational Science. 115: 421-53. PMID 23415100 DOI: 10.1016/B978-0-12-394587-7.00010-5 |
0.506 |
|
2013 |
Chidiac P, Hébert TE. GPCR Retreat 2012: timing is everything. Journal of Receptor and Signal Transduction Research. 33: 129-34. PMID 23351073 DOI: 10.3109/10799893.2012.759592 |
0.459 |
|
2013 |
Zhao P, Nunn C, Ramineni S, Hepler JR, Chidiac P. The Ras-binding domain region of RGS14 regulates its functional interactions with heterotrimeric G proteins Journal of Cellular Biochemistry. 114: 1414-1423. PMID 23255434 DOI: 10.1002/Jcb.24483 |
0.403 |
|
2012 |
Nguyen CH, Zhao P, Sobiesiak AJ, Chidiac P. RGS2 is a component of the cellular stress response. Biochemical and Biophysical Research Communications. 426: 129-34. PMID 22922103 DOI: 10.1016/J.Bbrc.2012.08.050 |
0.382 |
|
2012 |
Jones DL, Tuomi JM, Chidiac P. Role of Cholinergic Innervation and RGS2 in Atrial Arrhythmia. Frontiers in Physiology. 3: 239. PMID 22754542 DOI: 10.3389/Fphys.2012.00239 |
0.311 |
|
2011 |
Nunn C, Zhao P, Zou MX, Summers K, Guglielmo CG, Chidiac P. Resistance to age-related, normal body weight gain in RGS2 deficient mice. Cellular Signalling. 23: 1375-86. PMID 21447383 DOI: 10.1016/J.Cellsig.2011.03.020 |
0.356 |
|
2010 |
Nunn C, Zou MX, Sobiesiak AJ, Roy AA, Kirshenbaum LA, Chidiac P. RGS2 inhibits β-adrenergic receptor-induced cardiomyocyte hypertrophy Cellular Signalling. 22: 1231-1239. PMID 20362664 DOI: 10.1016/J.Cellsig.2010.03.015 |
0.443 |
|
2010 |
Zhao P, Nguyen CH, Chidiac P. The proline-rich N-terminal domain of G18 exhibits a novel G protein regulatory function. The Journal of Biological Chemistry. 285: 9008-17. PMID 20097748 DOI: 10.1074/Jbc.M109.057174 |
0.394 |
|
2010 |
Tuomi JM, Chidiac P, Jones DL. Evidence for enhanced M3 muscarinic receptor function and sensitivity to atrial arrhythmia in the RGS2-deficient mouse. American Journal of Physiology. Heart and Circulatory Physiology. 298: H554-61. PMID 19966055 DOI: 10.1152/Ajpheart.00779.2009 |
0.356 |
|
2009 |
Nguyen CH, Ming H, Zhao P, Hugendubler L, Gros R, Kimball SR, Chidiac P. Translational control by RGS2. The Journal of Cell Biology. 186: 755-65. PMID 19736320 DOI: 10.1083/Jcb.200811058 |
0.443 |
|
2009 |
Aziziyeh AI, Li TT, Pape C, Pampillo M, Chidiac P, Possmayer F, Babwah AV, Bhattacharya M. Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK. Cellular Signalling. 21: 1207-17. PMID 19306925 DOI: 10.1016/J.Cellsig.2009.03.011 |
0.542 |
|
2008 |
Chidiac P, Hébert TE. Meeting review: advances from the GPCR Retreat. Journal of Receptor and Signal Transduction Research. 28: 3-14. PMID 18437626 DOI: 10.1080/10799890801941962 |
0.39 |
|
2008 |
Chidiac P, Hébert T. Guest editors' introduction: the beginning of a happy tradition? Journal of Receptor and Signal Transduction Research. 28: 1-2. PMID 18437625 DOI: 10.1080/10799890801960541 |
0.634 |
|
2007 |
Wieland T, Lutz S, Chidiac P. Regulators of G protein signalling: a spotlight on emerging functions in the cardiovascular system Current Opinion in Pharmacology. 7: 201-207. PMID 17276730 DOI: 10.1016/J.Coph.2006.11.007 |
0.498 |
|
2006 |
Roy AA, Nunn C, Ming H, Zou MX, Penninger J, Kirshenbaum LA, Dixon SJ, Chidiac P. Up-regulation of endogenous RGS2 mediates cross-desensitization between Gs and Gq signaling in osteoblasts. The Journal of Biological Chemistry. 281: 32684-93. PMID 16950788 DOI: 10.1074/Jbc.M604416200 |
0.418 |
|
2006 |
Abramow-Newerly M, Ming H, Chidiac P. Modulation of subfamily B/R4 RGS protein function by 14-3-3 proteins. Cellular Signalling. 18: 2209-22. PMID 16839744 DOI: 10.1016/J.Cellsig.2006.05.011 |
0.505 |
|
2006 |
Nunn C, Mao H, Chidiac P, Albert PR. RGS17/RGSZ2 and the RZ/A family of regulators of G-protein signaling. Seminars in Cell & Developmental Biology. 17: 390-9. PMID 16765607 DOI: 10.1016/J.Semcdb.2006.04.001 |
0.506 |
|
2006 |
Zou MX, Roy AA, Zhao Q, Kirshenbaum LA, Karmazyn M, Chidiac P. RGS2 is upregulated by and attenuates the hypertrophic effect of alpha1-adrenergic activation in cultured ventricular myocytes. Cellular Signalling. 18: 1655-63. PMID 16517124 DOI: 10.1016/J.Cellsig.2006.01.012 |
0.489 |
|
2006 |
Abramow-Newerly M, Roy AA, Nunn C, Chidiac P. RGS proteins have a signalling complex: interactions between RGS proteins and GPCRs, effectors, and auxiliary proteins. Cellular Signalling. 18: 579-91. PMID 16226429 DOI: 10.1016/J.Cellsig.2005.08.010 |
0.507 |
|
2006 |
Roy AA, Baragli A, Bernstein LS, Hepler JR, Hébert TE, Chidiac P. RGS2 interacts with Gs and adenylyl cyclase in living cells. Cellular Signalling. 18: 336-48. PMID 16095880 DOI: 10.1016/J.Cellsig.2005.05.004 |
0.517 |
|
2005 |
Hepler JR, Cladman W, Ramineni S, Hollinger S, Chidiac P. Novel activity of RGS14 on Goalpha and Gialpha nucleotide binding and hydrolysis distinct from its RGS domain and GDI activity. Biochemistry. 44: 5495-502. PMID 15807543 DOI: 10.1021/Bi048359D |
0.391 |
|
2005 |
Gan XT, Rajapurohitam V, Haist JV, Chidiac P, Cook MA, Karmazyn M. Inhibition of phenylephrine-induced cardiomyocyte hypertrophy by activation of multiple adenosine receptor subtypes. The Journal of Pharmacology and Experimental Therapeutics. 312: 27-34. PMID 15452191 DOI: 10.1124/Jpet.104.073122 |
0.503 |
|
2004 |
Mao H, Zhao Q, Daigle M, Ghahremani MH, Chidiac P, Albert PR. RGS17/RGSZ2, a novel regulator of Gi/o, Gz, and Gq signaling. The Journal of Biological Chemistry. 279: 26314-22. PMID 15096504 DOI: 10.1074/Jbc.M401800200 |
0.52 |
|
2004 |
Bernstein LS, Ramineni S, Hague C, Cladman W, Chidiac P, Levey AI, Hepler JR. RGS2 binds directly and selectively to the M1 muscarinic acetylcholine receptor third intracellular loop to modulate Gq/11alpha signaling. The Journal of Biological Chemistry. 279: 21248-56. PMID 14976183 DOI: 10.1074/Jbc.M312407200 |
0.516 |
|
2003 |
Roy AA, Lemberg KE, Chidiac P. Recruitment of RGS2 and RGS4 to the plasma membrane by G proteins and receptors reflects functional interactions. Molecular Pharmacology. 64: 587-93. PMID 12920194 DOI: 10.1124/Mol.64.3.587 |
0.54 |
|
2003 |
Chidiac P, Roy AA. Activity, regulation, and intracellular localization of RGS proteins. Receptors & Channels. 9: 135-47. PMID 12775336 DOI: 10.3109/10606820308244 |
0.501 |
|
2003 |
Chakraborty C, Barbin YP, Chakrabarti S, Chidiac P, Dixon SJ, Lala PK. Endothelin-1 promotes migration and induces elevation of [Ca2+]i and phosphorylation of MAP kinase of a human extravillous trophoblast cell line. Molecular and Cellular Endocrinology. 201: 63-73. PMID 12706295 DOI: 10.1016/S0303-7207(02)00431-8 |
0.318 |
|
2003 |
Chidiac P. Guest Editor's Introduction: G Protein-Mediated Signaling: Some Complex Issues Receptors & Channels. 9: 133-133. DOI: 10.3109/10606820308241 |
0.412 |
|
2002 |
Cladman W, Chidiac P. Characterization and comparison of RGS2 and RGS4 as GTPase-activating proteins for m2 muscarinic receptor-stimulated G(i). Molecular Pharmacology. 62: 654-9. PMID 12181442 DOI: 10.1124/Mol.62.3.654 |
0.508 |
|
2002 |
Chidiac P. Considerations in the evaluation of inverse agonism and protean agonism at G protein-coupled receptors. Methods in Enzymology. 343: 3-16. PMID 11665576 DOI: 10.1016/S0076-6879(02)43124-2 |
0.53 |
|
2001 |
Santhanagopal A, Chidiac P, Horne WC, Baron R, Dixon SJ. Calcitonin (CT) Rapidly Increases Na+/H+ Exchange and Metabolic Acid Production: Effects Mediated Selectively by the C1a CT Receptor Isoform. Endocrinology. 142: 4401-4413. PMID 28201301 DOI: 10.1210/Endo.142.10.8411 |
0.365 |
|
2001 |
McKinnon T, Chakraborty C, Gleeson LM, Chidiac P, Lala PK. Stimulation of human extravillous trophoblast migration by IGF-II is mediated by IGF type 2 receptor involving inhibitory G protein(s) and phosphorylation of MAPK. The Journal of Clinical Endocrinology and Metabolism. 86: 3665-3674. PMID 11502794 DOI: 10.1210/Jcem.86.8.7711 |
0.387 |
|
2000 |
Scheschonka A, Dessauer CW, Sinnarajah S, Chidiac P, Shi CS, Kehrl JH. RGS3 Is a GTPase-Activating Protein for Giα and Gqα and a Potent Inhibitor of Signaling by GTPase-Deficient Forms of Gqα and G11α Molecular Pharmacology. 58: 719-728. PMID 10999941 DOI: 10.1124/Mol.58.4.719 |
0.487 |
|
1999 |
Chidiac P, Markin VS, Ross EM. Kinetic control of guanine nucleotide binding to soluble Galpha(q). Biochemical Pharmacology. 58: 39-48. PMID 10403517 DOI: 10.1016/S0006-2952(99)00080-5 |
0.556 |
|
1999 |
Chidiac P, Ross EM. Phospholipase C-beta1 directly accelerates GTP hydrolysis by Galphaq and acceleration is inhibited by Gbeta gamma subunits. The Journal of Biological Chemistry. 274: 19639-43. PMID 10391901 DOI: 10.1074/Jbc.274.28.19639 |
0.615 |
|
1998 |
Zeng W, Xu X, Popov S, Mukhopadhyay S, Chidiac P, Swistok J, Danho W, Yagaloff KA, Fisher SL, Ross EM, Muallem S, Wilkie TM. The N-terminal domain of RGS4 confers receptor-selective inhibition of G protein signaling. The Journal of Biological Chemistry. 273: 34687-90. PMID 9856989 DOI: 10.1074/Jbc.273.52.34687 |
0.734 |
|
1998 |
Ingi T, Krumins AM, Chidiac P, Brothers GM, Chung S, Snow BE, Barnes CA, Lanahan AA, Siderovski DP, Ross EM, Gilman AG, Worley PF. Dynamic regulation of RGS2 suggests a novel mechanism in G-protein signaling and neuronal plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 7178-88. PMID 9736641 DOI: 10.1523/Jneurosci.18-18-07178.1998 |
0.69 |
|
1998 |
Chidiac P. Rethinking receptor-G protein-effector interactions. Biochemical Pharmacology. 55: 549-556. PMID 9515565 DOI: 10.1016/S0006-2952(97)00361-4 |
0.53 |
|
1997 |
Green MA, Chidiac P, Wells JW. Cardiac muscarinic receptors. Relationship between the G protein and multiple states of affinity Biochemistry. 36: 7380-7394. PMID 9200685 DOI: 10.1021/Bi961940S |
0.522 |
|
1997 |
Chidiac P, Green MA, Pawagi AB, Wells JW. Cardiac muscarinic receptors. Cooperativity as the basis for multiple states of affinity Biochemistry. 36: 7361-7379. PMID 9200684 DOI: 10.1021/Bi961939T |
0.402 |
|
1997 |
Rousseau G, Guilbault N, Da Silva A, Mouillac B, Chidiac P, Bouvier M. Influence of receptor density on the patterns of beta2-adrenocepter desensitization. European Journal of Pharmacology. 326: 75-84. PMID 9178658 DOI: 10.1016/S0014-2999(97)00138-6 |
0.702 |
|
1995 |
Chidiac P. Receptor state and ligand efficacy. Trends in Pharmacological Sciences. 16: 83-84. PMID 7792933 DOI: 10.1016/S0165-6147(00)88986-5 |
0.355 |
|
1995 |
Bouvier M, Moffett S, Loisel TP, Mouillac B, Hebert T, Chidiac P. Palmitoylation of G-protein-coupled receptors: a dynamic modification with functional consequences. Biochemical Society Transactions. 23: 116-20. PMID 7758677 DOI: 10.1042/Bst0230116 |
0.751 |
|
1995 |
Bouvier M, Chidiac P, Hebert TE, Loisel TP, Moffett S, Mouillac B. Dynamic palmitoylation of G-protein-coupled receptors in eukaryotic cells. Methods in Enzymology. 250: 300-14. PMID 7651160 DOI: 10.1016/0076-6879(95)50080-4 |
0.776 |
|
1994 |
St-Onge S, Chidiac P, Brakier-Gingras L, Bouvier M. Beta-adrenergic receptor desensitization in the early stage of hereditary cardiomyopathy in hamsters. Canadian Journal of Physiology and Pharmacology. 72: 875-83. PMID 7834576 DOI: 10.1139/Y94-124 |
0.759 |
|
1992 |
Chidiac P, Wells JW. Effects of adenyl nucleotides and carbachol on cooperative interactions among G proteins Biochemistry. 31: 10908-10921. PMID 1420202 DOI: 10.1021/Bi00159A035 |
0.429 |
|
1991 |
Chidiac P, Nagy A, Sole MJ, Wells JW. Inefficient muscarinic transduction in cardiomyopathic Syrian hamsters. Journal of Molecular and Cellular Cardiology. 23: 1255-69. PMID 1666414 DOI: 10.1016/0022-2828(91)90083-X |
0.346 |
|
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