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Erik Chorell - Publications

Affiliations: 
Department of Chemistry Umeå University, Umeå, Västerbottens län, Sweden 
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Berner A, Das RN, Bhuma N, Golebiewska J, Abrahamsson A, Andréasson M, Chaudhari N, Doimo M, Bose PP, Chand K, Strömberg R, Wanrooij S, Chorell E. G4-Ligand-Conjugated Oligonucleotides Mediate Selective Binding and Stabilization of Individual G4 DNA Structures. Journal of the American Chemical Society. 146: 6926-6935. PMID 38430200 DOI: 10.1021/jacs.3c14408  0.681
2024 Andreasson M, Donzel M, Abrahamsson A, Berner A, Doimo M, Quiroga A, Eriksson A, Chao YK, Overman J, Pemberton N, Wanrooij S, Chorell E. Exploring the Dispersion and Electrostatic Components in Arene-Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands. Journal of Medicinal Chemistry. PMID 38241609 DOI: 10.1021/acs.jmedchem.3c02127  0.475
2023 Doimo M, Chaudhari N, Abrahamsson S, L'Hôte V, Nguyen TVH, Berner A, Ndi M, Abrahamsson A, Das RN, Aasumets K, Goffart S, Pohjoismäki JLO, López MD, Chorell E, Wanrooij S. Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells. Nucleic Acids Research. PMID 37351621 DOI: 10.1093/nar/gkad535  0.624
2023 Deiana M, Chand K, Chorell E, Sabouri N. Parallel G-Quadruplex DNA Structures from Nuclear and Mitochondrial Genomes Trigger Emission Enhancement in a Nonfluorescent Nano-aggregated Fluorine-Boron-Based Dye. The Journal of Physical Chemistry Letters. 14: 1862-1869. PMID 36779779 DOI: 10.1021/acs.jpclett.2c03301  0.414
2023 Bhuma N, Chand K, Andréasson M, Mason J, Das RN, Patel AK, Öhlund D, Chorell E. The effect of side chain variations on quinazoline-pyrimidine G-quadruplex DNA ligands. European Journal of Medicinal Chemistry. 248: 115103. PMID 36645982 DOI: 10.1016/j.ejmech.2023.115103  0.68
2022 Andréasson M, Bhuma N, Pemberton N, Chorell E. Using Macrocyclic G-Quadruplex Ligands to Decipher the Interactions Between Small Molecules and G-Quadruplex DNA. Chemistry (Weinheim An Der Bergstrasse, Germany). e202202020. PMID 35997141 DOI: 10.1002/chem.202202020  0.49
2022 Prasad B, Doimo M, Andréasson M, L'Hôte V, Chorell E, Wanrooij S. A complementary chemical probe approach towards customized studies of G-quadruplex DNA structures in live cells. Chemical Science. 13: 2347-2354. PMID 35310480 DOI: 10.1039/d1sc05816a  0.497
2021 Deiana M, Obi I, Andreasson M, Tamilselvi S, Chand K, Chorell E, Sabouri N. A Minimalistic Coumarin Turn-On Probe for Selective Recognition of Parallel G-Quadruplex DNA Structures. Acs Chemical Biology. PMID 34328300 DOI: 10.1021/acschembio.1c00134  0.54
2020 Das RN, Andréasson M, Kumar R, Chorell E. Macrocyclization of bis-indole quinolines for selective stabilization of G-quadruplex DNA structures. Chemical Science. 11: 10529-10537. PMID 34094311 DOI: 10.1039/d0sc03519j  0.709
2020 Obi I, Rentoft M, Singh V, Jamroskovic J, Chand K, Chorell E, Westerlund F, Sabouri N. Stabilization of G-quadruplex DNA structures in Schizosaccharomyces pombe causes single-strand DNA lesions and impedes DNA replication. Nucleic Acids Research. PMID 33045725 DOI: 10.1093/nar/gkaa820  0.439
2020 Deiana M, Chand K, Jamroskovic J, Das RN, Obi I, Chorell E, Sabouri N. A site-specific self-assembled light-up rotor probe for selective recognition and stabilization of c-MYC G-quadruplex DNA. Nanoscale. PMID 32525170 DOI: 10.1039/D0Nr03404E  0.682
2020 Prasad B, Das RN, Jamroskovic J, Kumar R, Hedenström M, Sabouri N, Chorell E. The Relation Between Position and Chemical Composition of Bis-Indole Substituents Determines their Interactions with G-Quadruplex DNA. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 32187406 DOI: 10.1002/Chem.202000579  0.707
2020 Jamroskovic J, Doimo M, Chand K, Obi I, Kumar R, Brännström K, Hedenström M, Nath Das R, Akhunzianov A, Deiana M, Kasho K, Sulis Sato S, Pourbozorgi PL, Mason JE, Medini P, ... ... Chorell E, et al. Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization. Journal of the American Chemical Society. PMID 31990532 DOI: 10.1021/Jacs.9B11232  0.539
2020 Kumar R, Chand K, Bhowmik S, Das RN, Bhattacharjee S, Hedenström M, Chorell E. Subtle structural alterations in G-quadruplex DNA regulate site specificity of fluorescence light-up probes. Nucleic Acids Research. PMID 31912160 DOI: 10.1093/Nar/Gkz1205  0.706
2020 Deiana M, Chand K, Jamroskovic J, Obi I, Chorell E, Sabouri N. A Light-up Logic Platform for Selective Recognition of Parallel G-Quadruplex Structures via Disaggregation-Induced Emission. Angewandte Chemie (International Ed. in English). 59: 896-902. PMID 31644837 DOI: 10.1002/Anie.201912027  0.55
2020 Das r, Andréasson M, Kumar R, Chorell E. Macrocyclization of Bis-Indole Quinolines for Selective Stabilization of G-quadruplex DNA Structures Chemical Science. DOI: 10.1039/D0Sc03519J  0.719
2019 Jamroskovic J, Obi I, Movahedi A, Chand K, Chorell E, Sabouri N. Identification of putative G-quadruplex DNA structures in S. pombe genome by quantitative PCR stop assay. Dna Repair. 82: 102678. PMID 31473486 DOI: 10.1016/J.Dnarep.2019.102678  0.574
2018 Bhattacharjee S, Chakraborty S, Chorell E, Sengupta PK, Bhowmik S. Importance of the hydroxyl substituents in the B-ring of plant flavonols on their preferential binding interactions with VEGF G-quadruplex DNA: Multi-spectroscopic and molecular modeling studies. International Journal of Biological Macromolecules. PMID 29953891 DOI: 10.1016/J.Ijbiomac.2018.06.115  0.555
2018 Prasad B, Jamroskovic J, Bhowmik S, Kumar R, Romell T, Sabouri N, Chorell E. Flexible versus rigid G-quadruplex DNA ligands - synthesis of two series of bis-indole derivatives and comparison of their interactions with G-quadruplex DNA. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29603472 DOI: 10.1002/Chem.201800078  0.619
2017 Pokrzywa M, Pawełek K, Kucia WE, Sarbak S, Chorell E, Almqvist F, Wittung-Stafshede P. Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease. Plos One. 12: e0184117. PMID 28863169 DOI: 10.1371/Journal.Pone.0184117  0.305
2017 Livendahl M, Jamroskovic J, Hedenström M, Görlich T, Sabouri N, Chorell E. Synthesis of phenanthridine spiropyrans and studies of their effects on G-quadruplex DNA. Organic & Biomolecular Chemistry. PMID 28349141 DOI: 10.1039/C7Ob00300E  0.62
2016 Jamroskovic J, Livendahl M, Eriksson J, Chorell E, Sabouri N. Identification of Compounds that Selectively Stabilize Specific G-Quadruplex Structures by Using a Thioflavin T-Displacement Assay as a Tool. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27862378 DOI: 10.1002/Chem.201603463  0.602
2016 Livendahl M, Jamroskovic J, Ivanova S, Demirel P, Sabouri N, Chorell E. Design and synthesis of 2,2'-diindolylmethanes to selectively target certain G-quadruplex DNA structures. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27431593 DOI: 10.1002/Chem.201602416  0.594
2016 Good JA, Andersson C, Hansen S, Wall J, Krishnan KS, Begum A, Grundström C, Niemiec MS, Vaitkevicius K, Chorell E, Wittung-Stafshede P, Sauer UH, Sauer-Eriksson AE, Almqvist F, Johansson J. Attenuating Listeria monocytogenes Virulence by Targeting the Regulatory Protein PrfA. Cell Chemical Biology. 23: 404-14. PMID 26991105 DOI: 10.1016/J.Chembiol.2016.02.013  0.384
2015 Chorell E, Andersson E, Evans ML, Jain N, Götheson A, Åden J, Chapman MR, Almqvist F, Wittung-Stafshede P. Bacterial Chaperones CsgE and CsgC Differentially Modulate Human α-Synuclein Amyloid Formation via Transient Contacts. Plos One. 10: e0140194. PMID 26465894 DOI: 10.1371/Journal.Pone.0140194  0.316
2015 Evans ML, Chorell E, Taylor JD, Ã…den J, Götheson A, Li F, Koch M, Sefer L, Matthews SJ, Wittung-Stafshede P, Almqvist F, Chapman MR. The bacterial curli system possesses a potent and selective inhibitor of amyloid formation. Molecular Cell. 57: 445-55. PMID 25620560 DOI: 10.1016/J.Molcel.2014.12.025  0.327
2015 Engström P, Krishnan KS, Ngyuen BD, Chorell E, Normark J, Silver J, Bastidas RJ, Welch MD, Hultgren SJ, Wolf-Watz H, Valdivia RH, Almqvist F, Bergström S. A 2-pyridone-amide inhibitor targets the glucose metabolism pathway of Chlamydia trachomatis. Mbio. 6: e02304-14. PMID 25550323 DOI: 10.1128/Mbio.02304-14  0.365
2014 Kindahl T, Chorell E. Efficient one-step synthesis of 4-amino substituted phthalimides and evaluation of their potential as fluorescent probes. Organic & Biomolecular Chemistry. 12: 4461-70. PMID 24849574 DOI: 10.1039/C4Ob00342J  0.365
2014 Dang HT, Chorell E, Uvell H, Pinkner JS, Hultgren SJ, Almqvist F. Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity. Organic & Biomolecular Chemistry. 12: 1942-56. PMID 24531242 DOI: 10.1039/C3Ob42478B  0.427
2014 Kindahl T, Chorell E, Chorell E. Development and optimization of simple one-step methods for the synthesis of 4-amino-substituted 1,8-naphthalimides European Journal of Organic Chemistry. 2014: 6175-6182. DOI: 10.1002/Ejoc.201402684  0.326
2013 Krishnan KS, Bengtsson C, Good JA, Mirkhanov S, Chorell E, Johansson LB, Almqvist F. Synthesis of fluorescent ring-fused 2-pyridone peptidomimetics. The Journal of Organic Chemistry. 78: 12207-13. PMID 24161000 DOI: 10.1021/Jo401844Y  0.338
2013 Andersson EK, Bengtsson C, Evans ML, Chorell E, Sellstedt M, Lindgren AE, Hufnagel DA, Bhattacharya M, Tessier PM, Wittung-Stafshede P, Almqvist F, Chapman MR. Modulation of curli assembly and pellicle biofilm formation by chemical and protein chaperones. Chemistry & Biology. 20: 1245-54. PMID 24035282 DOI: 10.1016/J.Chembiol.2013.07.017  0.352
2012 Chorell E, Pinkner JS, Bengtsson C, Banchelin TS, Edvinsson S, Linusson A, Hultgren SJ, Almqvist F. Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study. Bioorganic & Medicinal Chemistry. 20: 3128-42. PMID 22464688 DOI: 10.1016/J.Bmc.2012.01.048  0.368
2012 Han Z, Pinkner JS, Ford B, Chorell E, Crowley JM, Cusumano CK, Campbell S, Henderson JP, Hultgren SJ, Janetka JW. Lead optimization studies on FimH antagonists: discovery of potent and orally bioavailable ortho-substituted biphenyl mannosides. Journal of Medicinal Chemistry. 55: 3945-59. PMID 22449031 DOI: 10.1021/Jm300165M  0.36
2012 Chorell E, Pinkner JS, Bengtsson C, Edvinsson S, Cusumano CK, Rosenbaum E, Johansson LB, Hultgren SJ, Almqvist F. Design and synthesis of fluorescent pilicides and curlicides: bioactive tools to study bacterial virulence mechanisms. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 4522-32. PMID 22431310 DOI: 10.1002/Chem.201103936  0.369
2012 Horvath I, Weise CF, Andersson EK, Chorell E, Sellstedt M, Bengtsson C, Olofsson A, Hultgren SJ, Chapman M, Wolf-Watz M, Almqvist F, Wittung-Stafshede P. Mechanisms of protein oligomerization: inhibitor of functional amyloids templates α-synuclein fibrillation. Journal of the American Chemical Society. 134: 3439-44. PMID 22260746 DOI: 10.1021/Ja209829M  0.31
2011 Chorell E, Bengtsson C, Sainte-Luce Banchelin T, Das P, Uvell H, Sinha AK, Pinkner JS, Hultgren SJ, Almqvist F. Synthesis and application of a bromomethyl substituted scaffold to be used for efficient optimization of anti-virulence activity. European Journal of Medicinal Chemistry. 46: 1103-16. PMID 21316127 DOI: 10.1016/J.Ejmech.2011.01.025  0.383
2010 Chorell E, Pinkner JS, Phan G, Edvinsson S, Buelens F, Remaut H, Waksman G, Hultgren SJ, Almqvist F. Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: pilicides with increased antivirulence activity. Journal of Medicinal Chemistry. 53: 5690-5. PMID 20586493 DOI: 10.1021/Jm100470T  0.383
2009 Cegelski L, Pinkner JS, Hammer ND, Cusumano CK, Hung CS, Chorell E, Aberg V, Walker JN, Seed PC, Almqvist F, Chapman MR, Hultgren SJ. Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nature Chemical Biology. 5: 913-9. PMID 19915538 DOI: 10.1038/Nchembio.242  0.328
2008 Berg V, Das P, Chorell E, Hedenström M, Pinkner JS, Hultgren SJ, Almqvist F. Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli. Bioorganic & Medicinal Chemistry Letters. 18: 3536-40. PMID 18499455 DOI: 10.1016/J.Bmcl.2008.05.020  0.305
2007 Chorell E, Das P, Almqvist F. Diverse functionalization of thiazolo ring-fused 2-pyridones. The Journal of Organic Chemistry. 72: 4917-24. PMID 17539684 DOI: 10.1021/Jo0704053  0.325
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