| Year |
Citation |
Score |
| 2021 |
Besada P, Viña D, Costas T, Costas-Lago MC, Vila N, Torres-Terán I, Sturlese M, Moro S, Terán C. Pyridazinones containing dithiocarbamoyl moieties as a new class of selective MAO-B inhibitors. Bioorganic Chemistry. 115: 105203. PMID 34371375 DOI: 10.1016/j.bioorg.2021.105203 |
0.521 |
|
| 2020 |
Rodríguez-Enríquez F, Costas-Lago MC, Besada P, Alonso-Pena M, Torres-Terán I, Viña D, Fontenla JÁ, Sturlese M, Moro S, Quezada E, Terán C. Novel coumarin-pyridazine hybrids as selective MAO-B inhibitors for the Parkinson's disease therapy. Bioorganic Chemistry. 104: 104203. PMID 32932120 DOI: 10.1016/J.Bioorg.2020.104203 |
0.497 |
|
| 2016 |
Saíz-Urra L, Teijeira M, Rivero-Buceta V, Helguera AM, Celeiro M, Terán MC, Besada P, Borges F. Topological sub-structural molecular design (TOPS-MODE): a useful tool to explore key fragments of human A3 adenosine receptor ligands. Molecular Diversity. 20: 55-76. PMID 26205409 DOI: 10.1007/s11030-015-9617-z |
0.416 |
|
| 2016 |
Vila N, Besada P, Viña D, Sturlese M, Moro S, Terán C. Synthesis, biological evaluation and molecular modeling studies of phthalazin-1(2: H)-one derivatives as novel cholinesterase inhibitors Rsc Advances. 6: 46170-46185. DOI: 10.1039/C6Ra03841G |
0.507 |
|
| 2010 |
Costas T, Besada P, Piras A, Acevedo L, Yañez M, Orallo F, Laguna R, Terán C. New pyridazinone derivatives with vasorelaxant and platelet antiaggregatory activities. Bioorganic & Medicinal Chemistry Letters. 20: 6624-7. PMID 20880705 DOI: 10.1016/J.Bmcl.2010.09.031 |
0.367 |
|
| 2010 |
Wang Z, Do CW, Avila MY, Peterson-Yantorno K, Stone RA, Gao ZG, Joshi B, Besada P, Jeong LS, Jacobson KA, Civan MM. Nucleoside-derived antagonists to A3 adenosine receptors lower mouse intraocular pressure and act across species. Experimental Eye Research. 90: 146-54. PMID 19878673 DOI: 10.1016/J.Exer.2009.10.001 |
0.637 |
|
| 2010 |
Estévez L, Besada P, Fall Y, Teijeira M, Terán C. Stereoselective Synthesis ofNovel Isonucleoside Analogues of Purine with a Tetrahydropyran Ring Synthesis. 2010: 425-430. DOI: 10.1055/S-0029-1217142 |
0.309 |
|
| 2008 |
Mamedova LK, Wang R, Besada P, Liang BT, Jacobson KA. Attenuation of apoptosis in vitro and ischemia/reperfusion injury in vivo in mouse skeletal muscle by P2Y6 receptor activation. Pharmacological Research : the Official Journal of the Italian Pharmacological Society. 58: 232-9. PMID 18805489 DOI: 10.1016/J.Phrs.2008.08.004 |
0.777 |
|
| 2008 |
Ko H, Carter RL, Cosyn L, Petrelli R, de Castro S, Besada P, Zhou Y, Cappellacci L, Franchetti P, Grifantini M, Van Calenbergh S, Harden TK, Jacobson KA. Synthesis and potency of novel uracil nucleotides and derivatives as P2Y2 and P2Y6 receptor agonists. Bioorganic & Medicinal Chemistry. 16: 6319-32. PMID 18514530 DOI: 10.1016/J.Bmc.2008.05.013 |
0.845 |
|
| 2008 |
Gao ZG, Hechler B, Besada P, Gachet C, Jacobson KA. Caged agonist of P2Y1 and P2Y12 receptors for light-directed facilitation of platelet aggregation. Biochemical Pharmacology. 75: 1341-7. PMID 18199424 DOI: 10.1016/J.Bcp.2007.10.037 |
0.676 |
|
| 2008 |
González MP, Besada P, González Moa MJ, Teijeira M, Terán C. New QSAR combined strategy for the design of A1 adenosine receptor agonists. Bioorganic & Medicinal Chemistry. 16: 1658-75. PMID 18068994 DOI: 10.1016/J.Bmc.2007.11.026 |
0.512 |
|
| 2008 |
Besada P, Moa MJG, Terán C. An Efficient Synthesis of PhosphonateDerivatives of 1,2-Disubstituted Carbocyclic Purine Nucleosideswith a Cyclopentane Ring Synthesis. 2008: 2363-2368. DOI: 10.1055/S-2008-1067166 |
0.315 |
|
| 2007 |
Palaniappan KK, Gao ZG, Ivanov AA, Greaves R, Adachi H, Besada P, Kim HO, Kim AY, Choe SA, Jeong LS, Jacobson KA. Probing the binding site of the A1 adenosine receptor reengineered for orthogonal recognition by tailored nucleosides. Biochemistry. 46: 7437-48. PMID 17542617 DOI: 10.1021/Bi7001828 |
0.792 |
|
| 2007 |
Ivanov AA, Ko H, Cosyn L, Maddileti S, Besada P, Fricks I, Costanzi S, Harden TK, Calenbergh SV, Jacobson KA. Molecular modeling of the human P2Y2 receptor and design of a selective agonist, 2'-amino-2'-deoxy-2-thiouridine 5'-triphosphate. Journal of Medicinal Chemistry. 50: 1166-76. PMID 17302398 DOI: 10.1021/Jm060903O |
0.817 |
|
| 2006 |
Besada P, Mamedova LK, Palaniappan KK, Gao ZG, Joshi BV, Jeong LS, Civan MM, Jacobson KA. NUCLEOSIDE PRODRUGS OF A ADENOSINE RECEPTOR AGONISTS AND ANTAGONISTS. Collection of Czechoslovak Chemical Communications. 71: 912-928. PMID 34815583 DOI: 10.1135/cccc20060912 |
0.795 |
|
| 2006 |
Besada P, Shin DH, Costanzi S, Ko H, Mathé C, Gagneron J, Gosselin G, Maddileti S, Harden TK, Jacobson KA. Structure-activity relationships of uridine 5'-diphosphate analogues at the human P2Y6 receptor. Journal of Medicinal Chemistry. 49: 5532-43. PMID 16942026 DOI: 10.1021/Jm060485N |
0.832 |
|
| 2006 |
Jacobson KA, Costanzi S, Joshi BV, Besada P, Shin DH, Ko H, Ivanov AA, Mamedova L. Agonists and antagonists for P2 receptors. Novartis Foundation Symposium. 276: 58-68; discussion 68. PMID 16805423 DOI: 10.1002/9780470032244.Ch6 |
0.784 |
|
| 2006 |
Jacobson KA, Costanzi S, Ivanov AA, Tchilibon S, Besada P, Gao ZG, Maddileti S, Harden TK. Structure activity and molecular modeling analyses of ribose- and base-modified uridine 5'-triphosphate analogues at the human P2Y2 and P2Y4 receptors. Biochemical Pharmacology. 71: 540-9. PMID 16359641 DOI: 10.1016/J.Bcp.2005.11.010 |
0.847 |
|
| 2006 |
Besada P, Mamedova LK, Palaniappan KK, Gao ZG, Joshi BV, Jeong LS, Civan MM, Jacobson KA. Nucleoside prodrugs of A3 adenosine receptor agonists and antagonists Collection of Czechoslovak Chemical Communications. 71: 912-928. DOI: 10.1135/Cccc20060912 |
0.788 |
|
| 2005 |
González MP, Terán C, Teijeira M, Besada P, González-Moa MJ. BCUT descriptors to predicting affinity toward A3 adenosine receptors. Bioorganic & Medicinal Chemistry Letters. 15: 3491-5. PMID 15990306 DOI: 10.1016/J.Bmcl.2005.05.122 |
0.56 |
|
| 2005 |
Besada P, Mamedova L, Thomas CJ, Costanzi S, Jacobson KA. Design and synthesis of new bicyclic diketopiperazines as scaffolds for receptor probes of structurally diverse functionality. Organic & Biomolecular Chemistry. 3: 2016-25. PMID 15889186 DOI: 10.1039/B416349D |
0.824 |
|
| 2005 |
González MP, Terán C, Teijeira M, Besada P. Geometry, topology, and atom-weights assembly descriptors to predicting A1 adenosine receptors agonists. Bioorganic & Medicinal Chemistry Letters. 15: 2641-5. PMID 15863334 DOI: 10.1016/J.Bmcl.2005.03.028 |
0.514 |
|
| 2005 |
Jacobson KA, Mamedova L, Joshi BV, Besada P, Costanzi S. Molecular recognition at adenine nucleotide (P2) receptors in platelets. Seminars in Thrombosis and Hemostasis. 31: 205-16. PMID 15852224 DOI: 10.1055/S-2005-869526 |
0.837 |
|
| 2005 |
González MP, Terán C, Fall Y, Teijeira M, Besada P. A radial distribution function approach to predict A(2B) agonist effect of adenosine analogues. Bioorganic & Medicinal Chemistry. 13: 601-8. PMID 15653328 DOI: 10.1016/J.Bmc.2004.10.063 |
0.374 |
|
| 2004 |
Cattaneo M, Lecchi A, Ohno M, Joshi BV, Besada P, Tchilibon S, Lombardi R, Bischofberger N, Harden TK, Jacobson KA. Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor. Biochemical Pharmacology. 68: 1995-2002. PMID 15476670 DOI: 10.1016/J.Bcp.2004.06.026 |
0.71 |
|
| 2004 |
Jacobson KA, Costanzi S, Ohno M, Joshi BV, Besada P, Xu B, Tchilibon S. Molecular recognition at purine and pyrimidine nucleotide (P2) receptors. Current Topics in Medicinal Chemistry. 4: 805-19. PMID 15078212 DOI: 10.2174/1568026043450961 |
0.827 |
|
| 2003 |
Besada P, González-Moa MJ, Terán C, Teijeira M, Santana L. Synthesis of Carbocyclic Analogues of MECA and NECA 1,2-Disubstituted as Potential Adenosine Receptor Agonists Nucleosides, Nucleotides & Nucleic Acids. 22: 759-761. PMID 14565272 DOI: 10.1081/Ncn-120022628 |
0.545 |
|
| 1999 |
Besada P, Terán C, Santana L, Teijeira M, Uriarte E. Nucleoside Analogues of Purine with a 1,2-Disubstituted Cyclopentene Ring Nucleosides, Nucleotides & Nucleic Acids. 18: 725-726. DOI: 10.1080/15257779908041554 |
0.33 |
|
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